ライフサイエンスコーパス: beta-hydroxylase

1 s, due to a disruption the gene for dopamine beta-hydroxylase.

2 nking water of metyrapone, which inhibits 11-beta-hydroxylase.

3 of norepinephrine from dopamine by dopamine beta-hydroxylase.

4 enteric ganglia by the promoter for dopamine beta-hydroxylase.

5 the N-terminal regulatory region of dopamine beta-hydroxylase.

6 , ceruloplasmin, lysyl oxidase, and dopamine beta-hydroxylase.

7 ive genes, tyrosine hydroxylase and dopamine beta-hydroxylase.

8 y for choline acetyltransferase and dopamine beta-hydroxylase.

9 ed against tyrosine hydroxylase and dopamine-beta-hydroxylase.

10 inactivating the gene that encodes dopamine beta-hydroxylase.

11 g enzymes, tyrosine hydroxylase and dopamine-beta-hydroxylase.

12 en as the human form of aspartyl(asparaginyl)beta-hydroxylase.

13 ay enzymes tyrosine hydroxylase and dopamine beta-hydroxylase.

14 munoreactivity for dopamine but not dopamine beta-hydroxylase.

15 99 for aldosterone synthase compared with 11-beta-hydroxylase.

16 es a different mechanism than nonheme diiron beta-hydroxylases.

17 w expression there is enhanced GIBBERELLIN 3 BETA-HYDROXYLASE 1 (GA3ox1) expression, exhumed seeds ha

18 pressed in all Arabidopsis tissues analyzed, beta-hydroxylase 1 mRNA is always present at higher leve

19 ts in vivo that is structurally unrelated to beta-hydroxylase 1 or 2.

20 tical to the previously reported Arabidopsis beta-hydroxylase 1.

21 null mutant allele of LUT1, lut1-3, into the beta-hydroxylase 1/beta-hydroxylase 2 (b1 b2) double-mut

22 ivo, T-DNA knockout mutants corresponding to beta-hydroxylases 1 and 2 (b1 and b2, respectively) were

23 wo genes that encode beta-ring hydroxylases (beta-hydroxylases 1 and 2) have been identified in the A

24 of LUT1, lut1-3, into the beta-hydroxylase 1/beta-hydroxylase 2 (b1 b2) double-mutant background, in

25 nuclear antigen, and aspartyl-(asparaginyl)-beta-hydroxylase, a gene associated with increased cell

26 Aspartyl-(asparagyl)-beta-hydroxylase (AAH) is overexpressed in various malig

27 date compounds were tested for inhibition of beta-hydroxylase activity and selected for their capabil

28 ease in microsomal CYP3A dependent steroid 6 beta-hydroxylase activity but not in 90-day-old rats, po

29 Reduced beta-hydroxylase activity generated by the SMI MO-I-1100

30 AH protein in several tissues, lack aspartyl beta-hydroxylase activity in liver preparations, and exh

31 has been used successfully to assay aspartyl-beta-hydroxylase activity in microtiter plate format.

32 Beta-carotene hydroxylases (beta-hydroxylases) add hydroxyl groups to the beta-rings

33 Analyses of noradrenergic (dopamine-beta-hydroxylase) afferents revealed no differences in a

34 a cofactor to superoxide dismutase, dopamine-beta-hydroxylase, amyloid precursor protein, ceruloplasm

35 quent lipolysis, as do knockouts of dopamine beta-hydroxylase, an enzyme required for catecholamine s

36 he noradrenergic transmitter enzyme dopamine beta-hydroxylase and by using catecholamine histofluores

37 l complex that drives expression of dopamine-beta-hydroxylase and can also up-regulate expression of

38 density of axons immunoreactive for dopamine beta-hydroxylase and for serotonin.

39 coexist at significant levels with dopamine beta-hydroxylase and hence it is likely that this group

40 ubstances as well as for serotonin, dopamine-beta-hydroxylase and met-enkephalin are observed in the

41 ranule membrane proteins, including dopamine beta-hydroxylase and peptidyl glycine alpha-amidating en

42 al immunohistochemical detection of dopamine-beta-hydroxylase and PRV.

43 idence has shown that the genes for dopamine beta-hydroxylase and the dopamine transporter SLC6A3 may

44 ce domain, which is proposed to position the beta-hydroxylase and the NRPS-bound amino acid prior to

45 catecholamine biosynthetic enzymes, dopamine beta-hydroxylase and tyrosine hydroxylase, regulation of

46 copic levels to investigate whether dopamine-beta-hydroxylase and tyrosine hydroxylase-containing axo

47 ect evidence for the termination of dopamine-beta-hydroxylase and tyrosine hydroxylase-positive fiber

48 adrenergic differentiation markers dopamine beta-hydroxylase and tyrosine hydroxylase.

49 -ir) axons in the PF also expressed dopamine-beta-hydroxylase and were therefore noradrenergic or adr

50 egion of homology in catalysis for Asp (Asn) beta-hydroxylase and, by analogy, other alpha-ketoglutar

51 t also sufficient to induce Phox2b+ dopamine-beta-hydroxylase+ and tyrosine hydroxylase+ NA neurons i

52 s most often affected are 21-hydroxylase, 11 beta-hydroxylase, and 3 beta-hydroxysteroid dehydrogenas

53 ile inhibitors of aminopeptidase A, dopamine beta-hydroxylase, and the intestinal Na(+)/H(+) exchange

54 ls expressing tyrosine hydroxylase, dopamine-beta-hydroxylase, and the SA lineage marker SA-1 in near

55 Dopamine-beta-hydroxylase- and tyrosine hydroxylase-positive fibe

56 chieved by intrathecal injection of dopamine beta-hydroxylase antibodies conjugated to the toxin sapo

57 rvation utilizing a targeted-toxin (dopamine beta-hydroxylase antibody conjugated to saporin, DBH-Sap

58 sponse to psychological stress.Anti-dopamine-beta-hydroxylase antibody conjugated to the neurotoxin s

59 (spinal segments T2-T3) of an anti-dopamine-beta-hydroxylase antibody conjugated to the ribosomal to

60 In contrast, the use of an antidopamine beta-hydroxylase antiserum (which labels only adrenergic

61 AMP, protein complexes bound to the dopamine beta-hydroxylase AP1/cAMP response element element chang

62 mutant background, in which both Arabidopsis beta-hydroxylases are disrupted, yielded a genotype (lut

63 e(II)/alpha-ketoglutarate-dependent aspartyl beta-hydroxylases are identified in siderophore biosynth

64 abolizing enzymes and revealed the taxane 10 beta-hydroxylase as a 1494-bp cDNA that encodes a 498-re

65 nce identity to the aforementioned taxane 10 beta-hydroxylase) as a taxane 13 alpha-hydroxylase by ch

66 confirmed by coimmunolabeling with dopamine beta-hydroxylase, as well as by retrograde bone-brain tr

67 ate dependent oxygenase aspartate/asparagine-beta-hydroxylase (AspH) catalyses the hydroxylation of A

68 Human aspartate/asparagine-beta-hydroxylase (AspH) is a 2-oxoglutarate (2OG)-depend

69 Aspartyl-(asparaginyl)-beta-hydroxylase (ASPH) is a cell-surface enzyme that ge

70 Aspartate beta-hydroxylase (ASPH) is an enzyme overexpressed in hu

71 d DC population and load them with aspartate-beta-hydroxylase (ASPH), a highly expressed tumor-associ

72 OG)-dependent oxygenase aspartate/asparagine-beta-hydroxylase (AspH), are associated with Traboulsi s

73 ASPH encodes aspartyl/asparaginyl beta-hydroxylase (ASPH), which has been found to hydroxy

74 -oxoglutarate oxygenase aspartate/asparagine-beta-hydroxylase (AspH).

75 epsilon-ring hydroxylation but unrelated to beta-hydroxylases at the level of amino acid sequence.

76 Carotenoid beta-hydroxylases attach hydroxyl groups to the beta-ion

77 to PHA-L, tyrosine hydroxylase, and dopamine beta-hydroxylase, but not phenylethanolamine-N-methyltra

78 es, one of which was assigned as a taxane 10 beta-hydroxylase by functional expression in yeast.

79 Neither beta-hydroxylase cDNA maps to the LUT1 locus, and the ge

80 3 and PtmO6 represent the first dedicated C7 beta-hydroxylases characterized to date and, together wi

81 analysis of immunocytochemistry for dopamine beta-hydroxylase, choline acetyltransferase, and seroton

82 -injected rats pretreated with anti-dopamine-beta-hydroxylase conjugated to saporin to lesion hindbra

83 We have shown that an antibody to dopamine-beta-hydroxylase conjugated with saporin (anti-DBH-SAP)

84 R2)-mCherry (AAV2) into the RVLM of dopamine-beta-hydroxylase Cre transgenic mice (DbetaH(Cre/0)), mC

85 unilaterally into the brainstem of dopamine-beta-hydroxylase(Cre/0) mice.

86 for cortisol synthesis, including steroid 11 beta-hydroxylase (CYP11B1), and an enzyme that controls

87 Dopamine-beta-hydroxylase (D beta H) catalyzes the conversion of

88 ed to the antibody directed against dopamine beta hydroxylase (DbetaH-saporin), the analgesic and sed

89 out to investigate overlap between dopamine-beta-hydroxylase (DbetaH) -immunopositive projections an

90 rotein (pCREB) expressing nuclei in dopamine-beta-hydroxylase (DbetaH) containing cells in the LC.

91 nergic neurons were demonstrated by dopamine-beta-hydroxylase (DbetaH) immunofluorescence.

92 se in tyrosine-hydroxylase (TH) and dopamine beta-hydroxylase (DbetaH) immunoreactive (IR) axonal ter

93 Dopamine-beta-hydroxylase (DbetaH) is a copper-containing enzyme

94 et(MEN2B)) under the control of the dopamine-beta-hydroxylase (DbetaH) promoter develop profound neur

95 We used the human dopamine-beta-hydroxylase (DbetaH) promoter to direct transgenic

96 P) under the control of a synthetic dopamine-beta-hydroxylase (DbetaH) promoter was used to define ef

97 e catecholamine-synthesizing enzyme dopamine-beta-hydroxylase (DbetaH) was performed using confocal i

98 ral vectors into the brain of adult dopamine-beta-hydroxylase (DbetaH)(Cre/0) mice.

99 tions on tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DbetaH), and the norepinephrine transp

100 in and tyrosine hydroxylase (TH) or dopamine beta-hydroxylase (DbetaH), respectively.

101 An antibody raised against DA-beta-hydroxylase (DbetaH), the mammalian enzyme that con

102 volved in catecholamine metabolism, dopamine beta-hydroxylase (DbetaH), which converts dopamine to no

103 Quantification of dopamine beta-hydroxylase (DbetaH)-immunostained varicosities was

104 er 2 (VMAT2), serotonin (5-HT), and dopamine-beta-hydroxylase (DbetaH; a marker for norepinephrine) i

105 otonin, but did not directly affect dopamine beta hydroxylase (Dbh) expression in the locus coeruleus

106 enous tyrosine hydroxylase (TH) and dopamine-beta hydroxylase (DBH) gene expression in these cells.

107 ar tasks, ATP7A transfers copper to dopamine beta hydroxylase (DBH) within the lumen of the Golgi net

108 dramatically reduces expression of Dopamine Beta Hydroxylase (Dbh), a gene encoding a crucial catech

109 zed by immunoperoxidase labeling of dopamine beta hydroxylase (DbH), and gastric preautonomic PVN neu

110 hat express the NA synthetic enzyme dopamine beta hydroxylase (DbH)] in the caudal NST were lesioned

111 total phenotypic variance in plasma dopamine beta-hydroxylase (DBH) activity in samples from three di

112 Dopamine beta-hydroxylase (DBH) activity was associated with rs16

113 were exposed to antibodies against dopamine beta-hydroxylase (DBH) and 5-HT.

114 esis, tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) are absent.

115 Dopamine beta-hydroxylase (DBH) catalyzes the conversion of dopam

116 Dopamine beta-hydroxylase (DBH) catalyzes the production of norep

117 ly, immunohistochemical staining of dopamine-beta-hydroxylase (DBH) containing cells confirmed that s

118 norepinephrine (NE) deficiency (or dopamine beta-hydroxylase (DBH) deficiency) is a rare congenital

119 ormal tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) expression in sympathetic neurons

120 n was found to be downregulation of dopamine beta-hydroxylase (DBH) gene expression, encoding the enz

121 To examine if Egr1 also regulates dopamine beta-hydroxylase (DBH) gene expression, PC12 cells were

122 The dopamine beta-hydroxylase (DBH) gene is expressed selectively in

123 gated by targeted disruption of the dopamine beta-hydroxylase (Dbh) gene, thereby eliminating these c

124 eated by targeted disruption of the dopamine beta-hydroxylase (DBH) gene.

125 in vitro by retrograde tracing and dopamine beta-hydroxylase (DBH) immunocytochemistry.

126 etic genes tyrosine hydroxylase and dopamine beta-hydroxylase (DBH) is regulated by cell type-specifi

127 Dopamine beta-hydroxylase (DBH) is the biosynthetic enzyme cataly

128 Dopamine-beta-hydroxylase (DBH) is the penultimate enzyme require

129 cy in an AD mouse model, we crossed dopamine beta-hydroxylase (DBH) knockout mice with amyloid precur

130 ously showed that ethanol regulates dopamine beta-hydroxylase (DBH) mRNA and protein levels in human

131 Tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) mRNA expression in postmortem LC

132 pproach also allowed us to identify dopamine beta-hydroxylase (dbh) positive ganglion cells as a prev

133 Inhibition of dopamine beta-hydroxylase (DBH) results in a decrease in norepine

134 ymes, tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) was examined.

135 ses to CSD in mice deficient in NE [dopamine beta-hydroxylase (Dbh)(-/-)] and control male and female

136 targeted gene knockdown of NPY and dopamine-beta-hydroxylase (DBH), a catecholamine biosynthetic enz

137 immunocytochemical distribution of dopamine-beta-hydroxylase (DBH), a noradrenergic marker, in the b

138 In mice lacking dopamine beta-hydroxylase (DBH), an enzyme critical for NE synthe

139 active neurons was also labeled for dopamine-beta-hydroxylase (DBH), an enzyme involved in norepineph

140 e (VIP), tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DBH), and muscarinic and alpha(1)- and

141 urotransmitter synthesizing enzyme, dopamine beta-hydroxylase (DBH), could selectively destroy centra

142 marked by expression of the enzyme dopamine beta-hydroxylase (DBH), in female mice.

143 sses both the genes encoding TH and dopamine beta-hydroxylase (DBH), the key enzymes in norepinephrin

144 urons by inducing the expression of dopamine beta-hydroxylase (DBH), the terminal enzyme for noradren

145 ared the distribution and number of dopamine-beta-hydroxylase (DBH)- and phenylethanolamine-N-methylt

146 receptor population specifically in dopamine beta-hydroxylase (DBH)-expressing cells is both necessar

147 cystokinin (CCK) and noradrenergic, dopamine beta-hydroxylase (DBH)-expressing NTS neurons as two sep

148 the norepinephrine synthetic enzyme dopamine-beta-hydroxylase (DBH).

149 monooxygenase with low homology to dopamine beta-hydroxylase (DBH).

150 ic enzymes tyrosine hydroxylase and dopamine beta-hydroxylase (DBH).

151 the norepinephrine-synthetic enzyme dopamine beta-hydroxylase (DBH).

152 oreactive fibers did not co-contain dopamine beta-hydroxylase (DBH).

153 IP), tyrosine hydroxylase (TH), and dopamine-beta-hydroxylase (DBH).

154 ar sequence homologue of the enzyme dopamine beta-hydroxylase (DBH).

155 ase, tyrosine hydroxylase (TH), and dopamine beta-hydroxylase (DBH).

156 mice lacking NE due to mutation of dopamine beta-hydroxylase (dbh).

157 g the NTS neurons immunoreactive to dopamine beta-hydroxylase (DBH).

158 ic pathway that includes the enzyme dopamine-beta-hydroxylase (DBH).

159 ring the number and distribution of dopamine beta-hydroxylase (DBH)/cholinergic appositions, describe

160 Ethanol treatment elevated dopamine beta-hydroxylase (DBH, EC 1.14.17.1) mRNA and protein le

161 genetically by using mice that lack dopamine beta-hydroxylase (dbh-/- mice).

162 Gene-targeted mice that lack dopamine beta-hydroxylase (dbh-/-), the enzyme needed to convert

163 s the dopamine transporter (DAT) or dopamine beta-hydroxylase (DBH; marker of noradrenergic/adrenergi

164 ucts (tyrosine hydroxylase, Th, and dopamine beta-hydroxylase, Dbh) are markedly altered.

165 tyrosine hydroxylase, Th) and Dbh (dopamine beta-hydroxylase, Dbh) mRNA, whereas several other SNS g

166 g patients with recently documented dopamine beta-hydroxylase deficiency at a single institution.

167 a finding has never been described in an 11 beta-hydroxylase deficient individual.

168 ested this hypothesis in vivo using dopamine beta-hydroxylase-deficient mice (DBH -/-), which are una

169 Dopamine beta-hydroxylase-deficient mice (Dbh-/-), lacking catech

170 in delftibactin arises from the stand-alone beta-hydroxylase DelD.

171 alterobactin arise from hydroxylation by the beta-hydroxylase domain integrated into NRPS AltH, while

172 n conjugated to an antibody against dopamine beta hydroxylase (DSAP) was microinjected bilaterally in

173 ble factor (HIF)-1 (FIH-1) is an asparaginyl beta-hydroxylase enzyme that was initially found to hydr

174 case of a 15-year-old male, deficient in 11 beta-hydroxylase enzyme, presenting with hypertensive ha

175 converted to octopamine by the host tyramine beta-hydroxylase enzyme.

176 he evolutionarily related mammalian dopamine beta-hydroxylase enzyme.

177 b1 b2 double mutant, which lacks both known beta-hydroxylase enzymes, still contains significant lev

178 suggesting that a fourth unknown carotenoid beta-hydroxylase exists in vivo that is structurally unr

179 ied in our laboratory) in intron 8 of the 11-beta hydroxylase gene.

180 The mouse aspartyl beta-hydroxylase gene (Asph, BAH) has been cloned and ch

181 to the role of c-Fos in regulating dopamine beta-hydroxylase gene expression in response to cAMP, a

182 lanking -1012C --> T variant of the dopamine beta-hydroxylase gene was slightly increased and protect

183 e due to targeted disruption of the dopamine beta-hydroxylase gene, Dbh, were used to critically test

184 ne decarboxylase gene, tdc-1, and a tyramine beta-hydroxylase gene, tbh-1.

185 ivation of tyrosine hydroxylase and dopamine beta-hydroxylase genes after repeated episodes of stress

186 enomics-based approaches to isolate a second beta-hydroxylase genomic clone and its corresponding cDN

187 The human aspartyl (asparaginyl) beta-hydroxylase (HAAH) is a highly conserved enzyme tha

188 The S. typhimurium aspartyl/asparaginyl beta-hydroxylase homologue (designated lpxO) was cloned

189 In addition, dopamine-beta-hydroxylase immunohistochemistry, employed to deter

190 Previous studies have demonstrated dopamine-beta-hydroxylase immunoreactive (DBH-ir) fibers in the N

191 15 dorsal group and the very sparse dopamine-beta-hydroxylase immunoreactive fibers and varicosities

192 yrosine hydroxylase fibers, and not dopamine-beta-hydroxylase immunoreactive fibers, were located thr

193 No dopamine-beta-hydroxylase immunoreactive perikarya were observed

194 ty of tyrosine hydroxylase- but not dopamine-beta-hydroxylase-immunoreactive axons in sensory, motor,

195 Both tyrosine hydroxylase- and dopamine-beta-hydroxylase-immunoreactive fibers and punctate vari

196 Dopamine beta-hydroxylase-immunoreactive sympathetic nerves inner

197 sine hydroxylase-immunoreactive and dopamine-beta-hydroxylase-immunoreactive) were also quantified in

198 tyrosine hydroxylase perikarya, but dopamine-beta-hydroxylase immunoreactivity was very sparse within

199 activities of monoamine oxidase and dopamine beta hydroxylase in the hippocampus and prefrontal corte

200 ses to male song and the density of dopamine-beta-hydroxylase in area X and another song nucleus LMAN

201 yocytes expressing Dbhgene encoding dopamine beta-hydroxylase in murine heart.

202 axons immunoreactive for the enzyme dopamine-beta-hydroxylase in representative areas of acutely and

203 adrenaline (NA) and NA-synthesizing dopamine beta-hydroxylase in the peripheral nervous system.

204 similarity to mammalian aspartyl/asparaginyl beta-hydroxylases in bacteria known to make 2-hydroxyacy

205 onsistent with the presence of both types of beta-hydroxylases in the biosynthetic gene cluster.

206 hree homeologs), HYD1 and HYD2, which encode beta-hydroxylases in wheat.

207 nt the entire complement of non-heme di-iron beta-hydroxylases in wheat.

208 ese neurons were immunopositive for dopamine beta-hydroxylase, indicating that they were catecholamin

209 production was blocked by metyrapone, an 11-beta-hydroxylase inhibitor, females exhibited reduced se

210 howed previously that the selective dopamine beta-hydroxylase inhibitor, nepicastat, had no effect on

211 e examined tyrosine hydroxylase and dopamine-beta-hydroxylase innervation in hormonally intact adult

212 NPY knock-out (NPY KO) and dopamine beta-hydroxylase knock-out (DBH KO) mice that lack NE ar

213 Here, we exposed dopamine beta-hydroxylase knock-out (Dbh(-/-)) mice, which lack N

214 telemetrically monitoring the Tb of dopamine beta-hydroxylase knock-out (Dbh-/-) mice, which lack the

215 ethanol-mediated behaviors by using dopamine beta-hydroxylase knockout (Dbh -/-) mice that specifical

216 Additionally, dopamine beta-hydroxylase knockout (Dbh(-)(/)(-)) mice that do no

217 sts and examining motor deficits in dopamine beta-hydroxylase knockout (Dbh-/-) mice that lack NE alt

218 imulant responses by testing LRA in dopamine beta-hydroxylase knockout (Dbh-/-) mice that lack NE.

219 sverse aortic constriction (TAC) in dopamine beta-hydroxylase knockout mice (Dbh(-/-), genetically al

220 reatment with NE inhibitors, and in dopamine beta-hydroxylase knockout mice (which cannot synthesize

221 enomic region harbors monooxygenase dopamine beta-hydroxylase-like 1 gene (MOXD1), implicated in the

222 In a separate study, TH-ir and dopamine-beta-hydroxylase-like immunoreactivity (DBH-ir) were map

223 tro, and cAMP- and Phox2a-dependent dopamine-beta-hydroxylase-luciferase reporter expression.

224 mers to the phylogenetic tree of siderophore beta-hydroxylases, methods to predict beta-OHAsp stereoc

225 Dopamine beta-hydroxylase (-/-) mice are unable to synthesize NA

226 usceptibility was determined in the dopamine beta-hydroxylase null mutant (Dbh -/-) mouse using four

227 nce Raman spectroscopies show that CmlA, the beta-hydroxylase of the chloramphenicol biosynthetic pat

228 in, saporin-conjugated antiserum to dopamine-beta-hydroxylase, on acute restraint stress-induced acti

229 munostain for tyrosine hydroxylase, dopamine beta-hydroxylase, or neuropeptide Y.

230 to investigate the distribution of dopamine-beta-hydroxylase- or tyrosine-hydroxylase-labeled extran

231 hydroxylase, L-dopa decarboxylase, dopamine beta-hydroxylase, phenylethanolamine-N-methyltransferase

232 strate PHA-L, tyrosine hydroxylase, dopamine beta-hydroxylase, phenylethanolamine-N-methyltransferase

233 em sections were stained for c-Fos, dopamine beta-hydroxylase, phenylethanolamine-N-methyltransferase

234 rosine hydroxylase-positive but not dopamine-beta-hydroxylase-positive fibers, suggesting dopaminergi

235 s were in close proximity to single dopamine-beta-hydroxylase-positive varicosities, others, particul

236 ntrol of the noradrenergic-specific dopamine beta-hydroxylase promoter (DBH-hSNCA).

237 verexpress the galanin gene under a dopamine-beta-hydroxylase promoter (GalOE).

238 its cAMP-mediated expression of the dopamine beta-hydroxylase promoter construct in PC12 and CATH.a c

239 egulation of transcription from the dopamine beta-hydroxylase promoter is mediated by the AP1 protein

240 mproved Cre recombinase driven by a dopamine beta-hydroxylase promoter resulted in neuroblastoma deve

241 nsgenic mice were created using the dopamine beta-hydroxylase promoter to direct expression of RET(ME

242 converge on a single element in the dopamine beta-hydroxylase promoter to elicit activation of gene e

243 ss galanin under the control of the dopamine beta-hydroxylase promoter to study the neurochemical and

244 H-Ras in transgenic mice using the dopamine-beta-hydroxylase promoter, which directs expression to t

245 tant under the control of the human dopamine beta-hydroxylase promoter.

246 onatal lethality by expression of a dopamine beta-hydroxylase promoter/ET(B) receptor transgene (Tg/T

247 rescent protein under an artificial dopamine beta-hydroxylase (PRSx8) promoter to trace the spinal pr

248 emporal expression of TH, 5-HT, and dopamine beta hydroxylase reactivity, we determined that these fi

249 The 10 beta-hydroxylase represents the initial cytochrome P450

250 Immunostaining for dopamine beta-hydroxylase revealed fibers within dopamine (DA) ne

251 pecifically lesioning them with antidopamine beta-hydroxylase-saporin (DBH-SAP) injected via the 4th

252 Anti-dopamine beta-hydroxylase-saporin toxin (DbetaH-SAP) was used to

253 roventricularly with saline or anti-dopamine-beta-hydroxylase-saporin, a toxin that destroys noradren

254 Intracerebroventricular anti-dopamine beta-hydroxylase/saporin, a treatment that destroys a ma

255 y endocytosis assessed by measuring dopamine-beta-hydroxylase (secretory granule membrane) internaliz

256 By contrast, GA4, which encodes 3 beta-hydroxylase, showed low expression in stems and its

257 beta-Hydroxylase single mutants do not exhibit obvious g

258 ic enzymes tyrosine hydroxylase and dopamine beta-hydroxylase, suggesting a role for ARIX in expressi

259 r tyrosine hydroxylase, but not for dopamine-beta-hydroxylase, suggesting that these axonal arrays ar

260 We found that levels of tyramine beta-hydroxylase (TbetaH), an essential enzyme for the b

261 la melanogaster gene, which encodes tyramine beta-hydroxylase (TBH), the enzyme that catalyzes the la

262 We further show that the level of tyramine-beta-hydroxylase (TBH), the enzyme that converts tyramin

263 s, tyrosine decarboxylase (TDC) and tyramine beta-hydroxylase (TBH).

264 al residues in bovine aspartyl (asparaginyl) beta-hydroxylase that are located in a region of homolog

265 In contrast to the well studied beta-hydroxylases that have been cloned and characterize

266 ocalization of immunoreactivity for dopamine beta-hydroxylase (the synthetic enzyme for noradrenaline

267 alpha-2(A) adrenergic receptor and dopamine beta-hydroxylase, the enzyme necessary for NE synthesis.

268 ed mice lacking the gene coding for dopamine beta-hydroxylase, the enzyme responsible for synthesis o

269 ipts encoding NET, NET protein, and dopamine beta-hydroxylase; these neurons lack tyrosine hydroxylas

270 convert tyrosine into tyramine and tyramine beta-hydroxylase to convert tyramine into octopamine.

271 pared with tyrosine hydroxylase and dopamine beta-hydroxylase, to reflect the extent of adrenergic co

272 ies indicating direct activation of dopamine beta-hydroxylase transcription by Phox2a/2b, the present

273 ulation of tyrosine hydroxylase and dopamine beta-hydroxylase transcription was confirmed in PC12 cel

274 NE and dopamine beta-hydroxylase were increased by 3.8- and 10.7-fold, r

275 st 5-HT and the NA precursor enzyme dopamine beta-hydroxylase were utilized to examine the density of

276 closely related invertebrate enzyme tyramine-beta-hydroxylase, which converts tyramine to OA, suggest

277 noradrenergic biosynthetic enzyme, dopamine beta-hydroxylase, which is instead regulated by Ascl1.