ライフサイエンスコーパス: beta-lactam resistance

1 ence of C. diphtheriae BQ11 and mechanism of beta-lactam resistance.

2 ction, detoxification and aminoglycoside and beta-lactam resistance.

3 pGpp from antibiotic tolerance to high-level beta-lactam resistance.

4 idase activity of PBPs and to broad-spectrum beta-lactam resistance.

5 acterial activity and mediation of bacterial beta-lactam resistance.

6 vitro and exhibits altered pigmentation and beta-lactam resistance.

7 , consistent with a first step in developing beta-lactam resistance.

8 ides the major mechanism of plasmid-mediated beta-lactam resistance.

9 , consistent with a first-step in developing beta-lactam resistance.

10 ry, including strains that possess intrinsic beta-lactam resistance.

11 actamases and outer membrane porins affected beta-lactam resistance.

12 beta-lactam antibiotic turnover, facilitates beta-lactam resistance.

13 es isolates with characterized mechanisms of beta-lactam resistance, 180 clinical isolates from the M

14 we observed a rapid and stable evolution of beta-lactam resistance (20-fold MIC increase within 8 hr

15 The incidence of beta-lactam resistance among clinical isolates is a majo

16 AmpC beta-lactamase is a common mechanism of beta-lactam resistance among clinical isolates.

17 of transcription factors, also controls non-beta-lactam resistance and multiple virulence mechanisms

18 Tn4555 is an MTn that encodes beta-lactam resistance, and it is efficiently mobilized

19 ts of combination treatment on selection for beta-lactam resistance are not well understood.

20 In such organisms, beta-lactam resistance arises principally from beta-lact

21 eus strain did not precipitate a decrease in beta-lactam resistance as observed for fem (factor essen

22 resistance gene mecA caused complete loss of beta-lactam resistance but had no effect on the expressi

23 other enterobacteria, E. coli cells acquire beta-lactam resistance by ampD mutation.

24 YcbB did mediate beta-lactam resistance by insertion of multiple strands

25 lead to antibiotic resistance; for example, beta-lactam resistance by L,D-transpeptidase activities.

26 minantly belonging to the aminoglycoside and beta-lactam resistance classes.

27 of PBP2 of S. aureus prevents expression of beta-lactam resistance, despite the presence of the low-

28 in-binding protein 2a (PBP2a) is the primary beta-lactam resistance determinant of methicillin-resist

29 peptidoglycan transpeptidases, including the beta-lactam resistance determinant PBP2a, from MRSA.

30 ic distances between isolates with different beta-lactam resistance determinants suggests that the pr

31 ophilia, is a significant contributor to the beta-lactam resistance displayed by this opportunistic p

32 nal linkage between specific determinants of beta-lactam resistance (e.g. beta-lactamase) and redox p

33 s reaction regulates gene expression for the beta-lactam resistance enzyme, beta-lactamase.

34 Transposon inactivation of the beta-lactam resistance gene mecA caused complete loss of

35 Similarly, beta-lactams resistance gene ampC was more prevalent in

36 Among these, beta-lactam resistance genes -encoding beta-lactamases-

37 We assume that these novel beta-lactam resistance genes have evolved in concert wit

38 worldwide and rapid spread of large spectrum beta-lactam resistance genes such as carbapenemases is d

39 m minimum inhibitory concentration (MIC) and beta-lactam resistance genes with mortality in the MERIN

40 Functional metagenomics identified beta-lactam-resistance genes in treated and untreated so

41 nd the PBP5 synthesis repressor (Psr) to the beta-lactam resistance, growth, and cell autolysis of wi

42 ) methods for the detection of mecA-mediated beta-lactam resistance in 100 human isolates of S. epide

43 xpensive method for detecting PBP2a-mediated beta-lactam resistance in clinically relevant non-SASS f

44 Importantly, this protein is essential for beta-lactam resistance in community-acquired, methicilli

45 ttention to carbapenem and expanded-spectrum beta-lactam resistance in Escherichia coli, Klebsiella p

46 aluated for identification of PBP2a-mediated beta-lactam resistance in human and animal clinical isol

47 UgtP is required for beta-lactam resistance in methicillin-resistant S. aureu

48 ves was screened for the ability to suppress beta-lactam resistance in Mycobacterium smegmatis.

49 The development of beta-lactam resistance in non-SASS through acquisition a

50 ession of ospR alters pigment production and beta-lactam resistance in P. aeruginosa via a PA2826-ind

51 Overcoming beta-lactam resistance in pathogens such as Pseudomonas

52 llently despite the complexity of predicting beta-lactam resistance in pneumococci.

53 highly reliable for detecting mecA-mediated beta-lactam resistance in S. epidermidis isolates.

54 reakpoints reliably identified mecA-mediated beta-lactam resistance in S. epidermidis Using mecA PCR

55 f phenotypic methods to detect mecA-mediated beta-lactam resistance in staphylococci is becoming more

56 f laboratory testing to detect mecC-mediated beta-lactam resistance in Staphylococcus aureus Kriegesk

57 e of mecA, the determinant of broad-spectrum beta-lactam resistance in Staphylococcus aureus was rece

58 spore formation, and their specific links to beta-lactam resistance in this pathogen are underexplore

59 istance to erythromycin has been recognised, beta-lactam resistance in toxigenic diphtheria has not b

60 idate a prediction model for the presence of beta-lactam resistance in VGS causing bloodstream infect

61 strate viability, the PAD was used to detect beta-lactam resistance in wastewater and sewage and iden

62 Methicillin (beta-lactam) resistance in Staphylococcus epidermidis is

63 The results were then compared to the beta-lactam resistance mechanism determined by biochemic

64 This article reviews beta-lactam resistance mechanisms in staphylococci, curr

65 n of BLs is costly yet crucial to understand beta-lactam resistance mechanisms.

66 s linkage suggested to us that selection for beta-lactam resistance might coselect for capsular trans

67 starvation and stress responses provoke ampD beta-lactam resistance mutagenesis.

68 used in mutagenesis studies accumulate ampD beta-lactam resistance mutations independent of Lac reve

69 an assay system for studying enterobacterial beta-lactam resistance mutations using the well-develope

70 lation of PBP5 synthesis and consequently in beta-lactam resistance or in the regulation of cell auto

71 ovel genes involved with other mechanisms of beta-lactam resistance, peptidoglycan assembly, and cell

72 genes in the dacB-defective background, the beta-lactam resistance phenotype was abolished, disablin

73 Two hundred clinical isolates with varied beta-lactam resistance profiles were enrolled, with 196

74 ne mecA gene, the genetic determinant of the beta-lactam resistance protein PBP2A, had the opposite e

75 T software to search specific databases, the beta-lactam-resistance protein database of A. baumannii

76 ession of poxB in Escherichia coli conferred beta-lactam resistance to the host.

77 -lactamase-expression system does not confer beta-lactam resistance to the producer cell, and is enco

78 Some beta-lactam resistance was dependent on the expression o

79 To better define the role of sigma(M) in beta-lactam resistance, we characterized suppressor muta

80 ons in genes that are known to contribute to beta-lactam resistance were identified.

81 the pbp2m and blaOXA-2 genes (which code for beta-lactam resistance) were detected in a subgroup of i

82 to pConj acquisition, is spread of pbla and beta-lactam resistance, which we demonstrate here in vit

83 e that sigma(M) is responsible for intrinsic beta-lactam resistance, with sigma(X) playing a secondar