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1 4 of 5 patients reacted with sulfatide-bound beta2-glycoprotein I.
2 is reduction is dependent on the presence of beta2-glycoprotein I.
3 with anionic phospholipids in the absence of beta2-glycoprotein I.
4 attern with preferential reactivity to mouse beta2-glycoprotein I.
5                                              beta2-glycoprotein I, a plasma protein implicated in var
6 up 1 patients who were positive for IgA anti-beta2-glycoprotein I (aB2GP1) and B2A-CIC (n=125); group
7 ne origin, which are known to bind to plasma beta2-glycoprotein I (aka apolipoprotein H), correlates
8                               The binding of beta2-glycoprotein I also depends on the coating density
9 /-) mouse required the infusion of both anti-beta2-glycoprotein I and anti-phospholipid Ab.
10                    Two mAbs are specific for beta2-glycoprotein I and display a species-dependent pat
11 holipid antibodies, bound to sulfatide-bound beta2-glycoprotein I and previous absorption on cardioli
12 lly: 3 in serum (anticardiolipin antibodies, beta2-glycoprotein I, and anti-phosphatidyl-serine) and
13 ents and procoagulation factors such as anti-beta2-glycoprotein I (anti-beta2GPI) or anticardiolipin
14  antiphospholipid antibodies, including anti-beta2-glycoprotein-I (anti-beta2GPI), that are considere
15 , anticardiolipin antibodies (aCL), and anti-beta2-glycoprotein I antibodies (anti-beta2GPI) were als
16                   The prevalence of IgA anti-beta2-glycoprotein I antibodies (IgA-aB2GPI-ab) in patie
17 hase I trial of a tolerogen directed at anti-beta2-glycoprotein I antibodies demonstrated a decrease
18 , or positivity for anticardiolipin- or anti-beta2-glycoprotein I antibodies were not associated with
19 al anticardiolipin antibodies (aCL) (as anti-beta2-glycoprotein I antibodies) by semiquantitative 32P
20 body, IgA anticardiolipin antibody, and anti-beta2-glycoprotein I antibody.
21  investigated the role of the serum protein, beta2-glycoprotein I as an initiating Ag for Ab recognit
22 circulating immune complexes of IgA bound to beta2-glycoprotein I (B2A-CIC) has been associated with
23  anionic phospholipid and the plasma protein beta2-glycoprotein I (beta 2GPI) or the protein beta 2GP
24                                              beta2-Glycoprotein I (beta2-GPI) is an abundant plasma g
25 I as an initiating Ag for Ab recognition and beta2-glycoprotein I (beta2-GPI) peptides as a therapeut
26 ther anionic phospholipids in the absence of beta2-glycoprotein I (beta2-GPI).
27 ns that are recognized by the serum protein, beta2-glycoprotein I (beta2-GPI).
28 ibodies are directed against prothrombin and beta2-glycoprotein I beta2GPI), a phospholipid-binding p
29 n of the phospholipid binding plasma protein beta2 glycoprotein I (beta2GPI) for antibody binding and
30 antiphospholipid antibodies (aPL) binding to beta2 glycoprotein I (beta2GPI) induce endothelial cell-
31 PLAs associated with these events react with beta2 glycoprotein I (beta2GPI), and endothelial cell re
32 hospholipid-binding proteins (aPLs), such as beta2 glycoprotein I (beta2GPI).
33        Antiphospholipid antibodies targeting beta2-glycoprotein I (beta2GPI) are a hallmark of antiph
34                               Recognition of beta2-glycoprotein I (beta2GPI) by aPL antibodies appear
35                                Antibodies to beta2-glycoprotein I (beta2GPI) cause thrombosis in anti
36                                              beta2-glycoprotein I (beta2GPI) is the major antigen for
37                            Here we show that beta2-glycoprotein I (beta2GPI), a 50-kDa serum glycopro
38                              The function of beta2-glycoprotein I (beta2GPI), a 50-kDa serum glycopro
39                                              beta2-Glycoprotein I (beta2GPI), a phospholipid-binding
40   Most pathogenic APLAs are directed against beta2-glycoprotein I (beta2GPI), a plasma phospholipid b
41                                        Human beta2-glycoprotein I (beta2GPI), also known as apolipopr
42                                              beta2-glycoprotein I (beta2GPI)-dependent anticardiolipi
43 ted antibody, we treated mice immunized with beta2-glycoprotein I (beta2GPI).
44 recognize a conformational epitope shared by beta2-glycoprotein I (beta2GPI; the major autoantigen fo
45 nclude discovery of the crystal structure of beta2-glycoprotein I, (beta2GPI), genetic studies of bet
46                                      Soluble beta2-glycoprotein I binds to solid-phase ACA (immobiliz
47                                              Beta2-glycoprotein I binds to surface-bound sulfatides b
48 reased the immunoreactivity toward sulfatide-beta2-glycoprotein I complex by >50% in 12 of 14 patient
49                                At a constant beta2-glycoprotein I concentration of 5 microg/mL, maxim
50 riodontal disease status for serum levels of beta2-glycoprotein I-dependent anti-cardiolipin autoanti
51 4, which binds to anionic phospholipids in a beta2-glycoprotein I-dependent manner.
52  periodontitis have elevated serum levels of beta2-glycoprotein-I-dependent anti-cardiolipin (anti-CL
53                                    Thus, the beta2-glycoprotein I-derived peptides attenuate injury a
54           In this study, we examined whether beta2-glycoprotein I forms a complex with sulfatides and
55                                              Beta2-glycoprotein I is an anionic phospholipid-binding
56 entration of 5 microg/mL, maximal binding of beta2-glycoprotein I is observed at a coating density of
57 icroM, but if the reactants are reversed and beta2-glycoprotein I is on the solid-phase support, then
58  mice of anti-phospholipid Abs reacting with beta2-glycoprotein I may contribute to the pathogenesis
59 Ib or anionic phospholipid-binding proteins (beta2-glycoprotein I or annexin V) had no effect in thes
60 nionic phospholipid binding proteins such as beta2-glycoprotein I or annexin V.
61  sulfatide coating density of 1 microg/well, beta2-glycoprotein I reaches half-maximal binding at 2.5
62                     In addition, Abs against beta2 glycoprotein I restore local and remote tissue dam
63 indicated that binding of the serum protein, beta2-glycoprotein I, to the endothelium initiates a cas
64 lement system and is structurally related to beta2-glycoprotein I, which itself is known to bind to l
65 erived from the binding domain (domain V) of beta2-glycoprotein I would attenuate ischemia/reperfusio