ライフサイエンスコーパス: bilayer

1 g in a more natural and detergent-free lipid bilayer.

2 ent, hydrophobic interactions with the lipid bilayer.

3 ermine the ability of actin to adsorb to the bilayer.

4 hat the C-edge of betaarr1 engages the lipid bilayer.

5 -glycero-3-phosphocholine (DC(18:1)PC) lipid bilayer.

6 OF transporter and partition into the lipid bilayer.

7 -42) fragments that were closer to the lipid bilayer.

8 des are unaffected by dehydration within the bilayer.

9 the mechanical properties of the surrounding bilayer.

10 ecause of difficulties in modeling the lipid bilayer.

11 tate, each embedded in a phosphatidylcholine bilayer.

12 g mechanical force transmitted via the lipid bilayer.

13 eptides that interact with a supported lipid bilayer.

14 the exofacial and cytofacial aspects of the bilayer.

15 monomers, crosslinkers, and CTAs within the bilayer.

16 depends on their interactions with the lipid bilayer.

17 ee acyl coenzyme A (acyl-CoA) from the lipid bilayer.

18 an Na(V)1.7 and their affinity for the lipid bilayer.

19 mol % PS induces extensive reordering of the bilayer.

20 remarkable; it is a highly asymmetric lipid bilayer.

21 and their proximity with the supported lipid bilayer.

22 reas gamma-aminobutyric is excluded from the bilayer.

23 the bulky transport domain through the lipid bilayer.

24 he structural properties of the phospholipid bilayer.

25 the presence of cholesterol to pierce lipid bilayers.

26 s a MoN(2) layer sandwiched between two Si-N bilayers.

27 their in vivo orientation within fluid lipid bilayers.

28 in the vicinity of differently charged lipid bilayers.

29 cholesterol complexation with gp41 in lipid bilayers.

30 -angle x-ray scattering (WAXS) from oriented bilayers.

31 ns contribute to lateral clustering on lipid bilayers.

32 elated to a peptide-induced cross-linking of bilayers.

33 ane channels in cholesterol-containing lipid bilayers.

34 o potency at Na(V)1.7 and affinity for lipid bilayers.

35 cording of RyR2 activity in artificial lipid bilayers.

36 MAG are not presented as part of fluid lipid bilayers.

37 resembling the morphology of supported lipid bilayers.

38 ent conformational dynamics of MdfA in lipid bilayers.

39 of alphaS and modulates the binding to lipid bilayers.

40 ipids, especially near the midplane of lipid bilayers.

41 ted for membrane proteins in supported lipid bilayers.

42 unilamellar vesicles (SUVs) and planar lipid bilayers.

43 th or alter the physical properties of lipid bilayers.

44 ouplings between CDWs in neighbouring CuO(2) bilayers.

45 cal phenomena like phase separation in lipid bilayers.

46 from the conformation of the channel in POPC bilayers.

47 r that forms single channels in phospholipid bilayers.

48 had previously been shown to fuse with lipid bilayers.

49 tive pressures in liquids that contain lipid bilayers.

50 ctively transport anions across phospholipid bilayers.

51 complex Rabex5/Rabaptin5 on supported lipid bilayers.

52 nnel formation and pH gating in planar lipid bilayers.

53 ptical effects(8) in antiferromagnetic (AFM) bilayers.

54 ls but perturb the local properties of lipid bilayers.

55 that can otherwise pass through phospholipid bilayers.

56 s' association with zwitterionic and anionic bilayers.

57 he driving force of the reaction, large mono/bilayer (1.1 mm/200 mum) flakes or full-coverage films (

58 e domains (TMDs) are inserted into the lipid bilayer(3).

59 For twisted 3R bilayers, a tessellated pattern of mirror-reflected tria

60 odifier toxins have affinity for model lipid bilayers, a tripartite relationship among gating modifie

61 nspecific neurotransmitter adsorption to the bilayer-a process not considered in the established mode

62 face profile, which displays increased lipid bilayer affinity and in vitro activity at the voltage-ga

63 f diglycerides and free fatty acids into gum bilayers after PLC and 3G ED.

64 ide mimics of mucins and added them to lipid bilayers, allowing chemical control of length, glycosyla

65 he ratio of negatively charged lipids in the bilayer altered membrane bending and binding properties

66 No piezoelectricity is found in bilayer and bulk hBN, where the center of symmetry is re

67 omic distribution normal to the plane of the bilayer and imaging parameters.

68 orm low order oligomers on a supported lipid bilayer and that neither membrane association nor access

69 to maximise protein integration into a lipid bilayer and the oligomerisation of the protein into func

70 namics (MD) simulations in an explicit lipid bilayer and water environment (1.6 million atoms in tota

71 f cross-dismutation operates in phospholipid bilayers and cell culture.

72 ne protein W have been investigated in lipid bilayers and detergent micelles by solution NMR relaxati

73 determined that PlsX binds directly to lipid bilayers and identified its membrane anchoring moiety, c

74 the lipid-lipid interactions in model lipid bilayers and improve our understanding of the lateral or

75 onge phase contains a dense network of lipid bilayers and nanometric aqueous channels, which allows d

76 es to quantify protein-lipid interactions in bilayers and understand how membrane proteins remodel th

77 onsist of a protein belt surrounding a lipid bilayer, and are broadly used for characterization of me

78 ded hydrophilic side chains within the lipid bilayer, and it disengages concomitant with substrate fo

79 e de novo NMR structure in near-native lipid bilayers, and by accessing structural dynamics relevant

80 nel conductance measurements in planar lipid bilayers, and in vivo fluorescence imaging, we demonstra

81 rm water-filled nanoscale pores within lipid bilayers, and their properties are dependent on the comp

82 preserve the biophysical properties of lipid bilayers, and therefore, questions on binding specificit

83 teractions between actin filaments and lipid bilayers are possible and that the net charge of the bil

84 are possible and that the net charge of the bilayer as well as the presence of divalent ions in the

85 ) tetramers and octamers inserted into lipid bilayers as well-defined pores.

86 ned to evaluate the drug's affinity for DMPC bilayers, as well as to assess the drug's effects on the

87 ibit selective proton transport across lipid bilayers at a rate similar to those of natural proton ch

88 recombinant APOL1 inserts into planar lipid bilayers at acidic pH to form pH-gated nonselective cati

89 c simulations to be highly flexible in lipid bilayers at ambient temperature, with large rocking moti

90 These results with bilayers at physiological temperatures indicate that the

91 Our results suggest that bilayer-based cavitation is what generally limits the ma

92 ains to intercalated assemblies with polymer bilayers between sheets.

93 rrelated system based on small-angle twisted bilayer-bilayer graphene (TBBG), consisting of two rotat

94 ed membrane proteins depends on phospholipid bilayer biophysical properties.

95 e molecular orientations in the phospholipid bilayer but cannot resolve the actual distribution of mo

96 apsed conformation at the level of the lipid bilayer, but we observed a large, hydrophilic and fully

97 Composition of the lipid bilayer can be varied to bind and orient specific protei

98 e van der Waals interface of the TMDC hetero-bilayer can efficiently separate electrons and holes in

99 del membrane surface area and eventual lipid bilayer collapse.

100 on membrane molecules propagate to the lipid bilayer components to generate specific nanomechanical r

101 eight, flexible, transparent, and conductive bilayer composite of polyetherimide and single-layer gra

102 ations of the protein in a complex mammalian bilayer containing more than 60 different lipid types to

103 with both the receptor and the phospholipid bilayer contribute to its functional versatility.

104 rtion of hydrophobic moieties into the lipid bilayer core.

105 eimer's disease that the disruption of lipid bilayers correlates linearly with the time course of the

106 ng prediction of protein orientations in the bilayer, DeltaDeltaG calculations, native structure disc

107 channels embedded in planar suspended lipid bilayers demonstrate that anionic gold nanoparticles (Au

108 -soluble fluorophores to interact with lipid bilayers, detailed fluorophore-lipid interactions and, m

109 r a wide range of conditions and exhibit the bilayered-disc morphology of ideal bicelles even at low

110 opy indicates that AuNP interaction with the bilayer does not perturb the conformation of membrane-em

111 force alters the physical state of the lipid bilayer, driving mechanosensors to assume conformations

112 rporated into encapsulated droplet interface bilayers (eDIBs), or artificial cells, and the biolumine

113 sting that physical deformation of the lipid bilayer, either by mechanical force or curvature, can in

114 spike pore follows from predictions of lipid bilayer elasticity and offers an explanation for previou

115 e molecule approaches, nanodisc-based planar bilayer electrophysiology and single-molecule FRET, to a

116 Exosomes are lipid bilayer-enclosed EVs of 30-150 nm in diameter, which can

117 sphatase CD45 is more strongly excluded from bilayer-engaged BRCs than a transmembrane peptide, indic

118 l docking complex Pex14p/Pex17p, in a native bilayer environment, and reveal its subunit organization

119 membrane proteins in a detergent-free lipid-bilayer environment.

120 The fluidity of the lipid bilayer expressed as fluorescence anisotropy of the prob

121 o protrude through the enzyme into the lipid bilayer, facilitating the desaturation of very-long-chai

122 e signaling and reporter lipids, and control bilayer fluidity.

123 than the second-stage rate, associated with bilayer formation, indicating that the first-stage react

124 study demonstrates the role of phospholipid bilayer fragment as the key intermediate in the mechanis

125 isualize the fine structure of liposomes and bilayer fragments by CryoTEM.

126 ARS-CoV-2) virions are surrounded by a lipid bilayer from which spike (S) protein trimers protrude(1)

127 lm to study SLED's fundamental behavior in a bilayer geometry.

128 We thus establish twisted bilayer GeSe as an intriguing inroad into the strongly c

129 ons of lipid bilayer physical properties and bilayer-gramicidin interactions.

130 topological character in magic-angle twisted bilayer graphene (MATBG) has created a unique opportunit

131 uperconducting phases in magic-angle twisted bilayer graphene (MATBG)(1,2) crucially depend on the in

132 Magic-angle twisted bilayer graphene (TBG), with rotational misalignment clo

133 der Waals heterostructures of twisted double bilayer graphene (TDBG), we demonstrate a flat electron

134 t the observation of a QAH effect in twisted bilayer graphene aligned to hexagonal boron nitride.

135 cting states observed in magic-angle twisted-bilayer graphene and ABC trilayer graphene/boron nitride

136 ctroscopic properties of magic-angle twisted bilayer graphene as a function of electron filling, dete

137 e relative oscillator strength by tuning the bilayer graphene bandgap.

138 inter-LL optical transitions of high-quality bilayer graphene by photocurrent spectroscopy measuremen

139 Magic-angle twisted bilayer graphene exhibits a variety of electronic states

140 eation of weakly dispersive, 'flat' bands in bilayer graphene for certain 'magic' angles of twist bet

141 Recent experiments on twisted bilayer graphene have shown a high-temperature parent st

142 Twisted bilayer graphene is a key material in this regard becaus

143 Twisted bilayer graphene near the magic angle(1-4) exhibits rich

144 on the electronic band structure of twisted bilayer graphene using a back-gated device architecture

145 a moire superlattice potential (via aligning bilayer graphene with the top and/or bottom boron nitrid

146 and superconductivity in magic-angle twisted bilayer graphene(1,2) has enabled the experimental inves

147 ted insulating states in magic-angle twisted bilayer graphene(1-11) prompts fascinating questions abo

148 fect in the flat band of magic-angle twisted bilayer graphene(4-8) has sparked the exploration of cor

149 he inherent polarizability of Bernal-stacked bilayer graphene(7,8).

150 als, ranging from cuprate superconductors to bilayer graphene, and may arise from physics beyond the

151 ting of two rotated sheets of Bernal-stacked bilayer graphene.

152 es, in stark contrast to magic-angle twisted bilayer graphene.

153 e at low temperatures in magic-angle twisted bilayer graphene.

154 t for imaging moire superlattices of twisted bilayers graphene encapsulated by hexagonal boron nitrid

155 While twist angle between the bilayer has been shown to be a critical parameter in eng

156 n biophysical properties of the phospholipid bilayer have received little study.

157 Images of micrometer-scale domains in lipid bilayers have provided the gold standard of model-free e

158 l-space imaging of the edge structures of 2D bilayer hexagonal ice grown on a Au(111) surface.

159 h conventional views regarding the growth of bilayer hexagonal ices and 2D hexagonal matter in genera

160 r-type phosphatases was observed on the soft bilayers, however, even though it is yet to be demonstra

161 ell membranes and reconstituted phospholipid bilayers; however, the mechanisms by which these changes

162 y linked to the location of insertion in the bilayer (i.e., midplane or interface).

163 iochemical properties, nucleosides are lipid bilayer impermeable and thus rely on dedicated transport

164 ntercalation of sodium dodecyl sulfate (SDS) bilayers in a PEM comprising poly(diallyldimethylammoniu

165 e Sec translocon moves proteins across lipid bilayers in all cells.

166 -transfer agents (CTA) within self-assembled bilayers in an aqueous suspension enabled the successful

167 Because cells keep most of their lipid bilayers in an asymmetric nonequilibrium steady state, o

168 channel electrical recording in planar lipid bilayers in conjunction with protein engineering, we exp

169 re-gel droplets were connected through lipid bilayers in predetermined architectures and photopolymer

170 to form treadmilling filaments on supported bilayers in vitro(1), as well as in live cells, in which

171 PSFL1 can transfer PIP into PA-rich membrane bilayers in vitro, suggesting that CPSFL1 potentially fa

172 vivo, and can be reconstituted on supported bilayers in vitro.

173 We find that lipid bilayers, in contrast to small solutes, increase the rat

174 collective physical properties of the lipid bilayer influence 4E10 dynamics therein.

175 teristic of the solvation environment in the bilayer interfacial region.

176 s lateral movement of proteins in this lipid bilayer is possible, it is rather limited in turgid and

177 tJ (or TMBIM6) structure embedded in a lipid bilayer is uncharacterized, let alone the molecular mech

178 trates and catalyzes hydrolysis in the lipid bilayer is unclear.

179 , emulated by the PEG molecules at the lipid bilayer, is enough to promote the polymerization of the

180 ropic behavior, available free volume of the bilayer, its excess surface area, and bending elasticity

181 rthermore, we observe MBP to insert into its bilayer leaflet side in case of the diseased lipid mixtu

182 bles into a ring-shaped complex on the outer-bilayer leaflet.

183 verapamil dynamically flip flops between the bilayer leaflets, possibly rendering its net transport f

184 icial membranes, so-called sparsely tethered bilayer lipid membranes, reveal the structural aspects o

185 Non-bilayer lipids stimulate transport activity, but differe

186 phosphocholine (PGPC), and each of the three bilayer lipids, 1,2-dipalmitoyl-sn-glycero-3-phosphochol

187 herichia coli gene mreB inside vesicles with bilayers made of lipid-polyethylene glycol (PEG).

188 Twisted two-dimensional bilayer materials exhibit many exotic electronic phenome

189 ted actin network interacting with the lipid bilayer membrane have been assumed to control RBC shape,

190 der reconstitution process by increasing the bilayer membrane rigidity against the dehydration tensio

191 The bilayer membrane's combined properties of electrical con

192 r greigite (Fe(3)S(4)), enveloped by a lipid bilayer membrane, produced by magnetotactic bacteria.

193 o-myosin network linked to a supported lipid bilayer membrane.

194 hat control molecular transport across lipid bilayer membranes.

195 n nanopores and biological channels in lipid bilayer membranes.

196 Furthermore, this study expands the lipid-bilayer model by suggesting that the force-induced topol

197 explanations for mechanosensitivity, a lipid-bilayer model, suggests that a stretch of the membrane i

198 silico and in vitro assays to measure drugs' bilayer-modifying potency.

199 Lipid bilayer nanodiscs are an attractive tool to study membra

200 in 1 m Cl(-) solutions, comparable to lipid bilayers of a cell membrane.

201 o closed (elliptical) dispersion contours in bilayers of alpha-phase molybdenum trioxide (alpha-MoO(3

202 tains exclusively the outer leaflet of lipid bilayers of liposomes, as evidenced by leaflet-specific

203 In particular, we analyze in detail twisted bilayers of Neel antiferromagnets on the honeycomb latti

204 , and here we activate B-cells via supported bilayers of phosphatidylcholine lipids, a natural ligand

205 Here, we review regulation of the lipid bilayers of the NE and suggest ways to generate lipid as

206 omparing coexisting domains with homogeneous bilayers of the same composition, we demonstrate how dom

207 by atomic manipulation on a sodium chloride bilayer on Cu(111) at 5 K, and imaged by high-resolution

208 nding atomistic structure, and the potential bilayer orientation determined by TMDET algorithm of a g

209 The bilayer perovskite Sr(3)Ru(2)O(7) has been widely studie

210 becomes important to be able to predict the bilayer-perturbing potency of hydrophobic/amphiphilic dr

211 nergy by drug-induced perturbations of lipid bilayer physical properties and bilayer-gramicidin inter

212 teins at the interface, and/or modulation of bilayer physical properties.

213 at the CNTPs undergo diffusive motion in the bilayer plane.

214 MBP-mediated assembling of lipid bilayers proceeds in two steps, with a slow second step

215 hilic [Co(L3)](2+) complex into the liposome bilayer produces a more highly shifted CEST peak at -13

216 ts the nonexistence of the m-terminated TMDs bilayer products.

217 In this context, supported lipid bilayers provide a suitable platform to investigate memb

218 ire lattices formed in twisted van der Waals bilayers provide a unique, tunable platform to realize c

219 avity, which opens laterally to the membrane bilayer, providing lipid access to the active site.

220 33 and 49 cm(2) V(-1) s(-1) for the mono and bilayer regions) and on/off ratio (1 ~ 5 x 10(8)) across

221 n and controlled orientation relative to the bilayer remains challenging.

222 tubes capable of self-inserting into a lipid bilayer, represent a simplified model of biological memb

223 rane-embedded components within phospholipid bilayers represents a distinct class of phase transforma

224 ing a liquid-ordered phase is changed into a bilayer resembling a fluid-liquid-disordered phase surro

225 complexes induce a transformation in which a bilayer, resembling a liquid-ordered phase is changed in

226 ar dynamics (MD) simulations of phospholipid bilayers responding to electric fields.

227 binding via His-tag insertion into the CoPoP bilayer results in a serum-stable and conformationally i

228 ncured polydimethylsiloxane (PDMS) and fixed bilayer rings made of silicone grease and steel.

229 patterning nucleation sites on monolayer or bilayer s-TMDs, we precisely control the nucleation and

230 ar to saturated membranes, by increasing the bilayer's packing density.

231 ar vesicles (EVs) are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells.

232 teral membrane pressure profile in the lipid bilayer sensed by LHCII-bound peripheral pigments.

233 pid membrane of liposomes was characterized (bilayer size, chain conformational order, lateral packin

234 orm ITIR-FCS measurements on supported lipid bilayers (SLBs) of various lipid compositions to charact

235 hatidylserine (PS) lipids in supported lipid bilayers (SLBs), forming a PS-Zn(2+) complex with an equ

236 on than most other lipids in supported lipid bilayers (SLBs).

237 ion analysis, we find that BRCs engaged with bilayers sort minimal peptide markers of liquid-ordered

238 The dependence of the bilayer spacings (as observed by SANS and SAXS) on the r

239 It also results in bilayer-spanning segments containing polar monomers that

240 For twisted 2H bilayers, stable 2H domains dominate, with nuclei of a s

241 membrane homeostasis, we identified a lipid bilayer stress (LBS) sensor in the UPR transducer protei

242 fect originates from a looser swelling lipid bilayer structure due to the adsorption and electrostati

243 A hallmark feature of biological lipid bilayer structure is a depth-dependent polarity gradient

244 led that individual nanohelices consist of a bilayer structure with the outer and inner layers derive

245 he structural properties of the phospholipid bilayer, suggesting that both ionized and neutral states

246 Therefore, in the present work, a lipid-bilayer-supported printing technique is developed to 3D

247 groups stably anchored P2 on the myelin-like bilayer surface.

248 indicate that the presence of MGDG in lipid bilayers switches LHCII from a light-harvesting to a mor

249 SpA was attached to BioPE-DOTAP binary lipid bilayer tethered on alkane thiol molecular cushions.

250 nct alterations in the structure of the DMPC bilayer than the deprotonated/ionized form, considering

251 clofenac displayed greater affinity for DMPC bilayers than anionic diclofenac.

252 ram-negative bacteria is an asymmetric lipid bilayer that consists of inner leaflet phospholipids and

253 s of transient pores on a patch of the lipid bilayer that is strengthened by an elastic meshwork repr

254 In lipid bilayers that mimic the endoplasmic reticulum-Golgi inte

255 ICG interaction with the cell membrane lipid bilayer, the pharmacology and toxicology in vitro and in

256 Like in lipid bilayers, the hydrophobic shielding in the aggregates of

257 of liposome systems to DMSO in terms of the bilayer thermotropic behavior, available free volume of

258 we demonstrate that cryo-EM can distinguish bilayer thickness differences as small as 0.5 angstrom,

259 chains, hydrophobic lengths compatible with bilayer thickness, and polar pores.

260 drives membrane tubulation, constriction and bilayer thinning.

261 n a constitutively active state in POPC:POPG bilayers through the use of real-time fluorescence quenc

262 e extramembrane domain to be oriented in the bilayer, thus mimicking the in vivo situation.

263 gth hemagglutinin proteoliposome and a lipid bilayer to analyze these mechanisms.

264 n is ion specific, inducible by exposing the bilayer to muM concentrations of Zn(2+) but not Mg(2+),

265 ylethanol was incorporated into the liposome bilayer to provide the nanovesicles with fluorescence wi

266 easing the area per lipid on the side of the bilayer to which the salt was exposed.

267 esting complex II (LHCII) in thylakoid lipid bilayers to detect LHCII conformational dynamics in its

268 We developed a method for attaching lipid bilayers to polydimethylsiloxane polymer supports, produ

269 Using unstable supported lipid bilayers-transiently assembled via surface-mediated fusi

270 pathways of peptide insertion into the lipid bilayer (triggered by a pH drop) and peptide exit from t

271 ered by a pH drop) and peptide exit from the bilayer (triggered by a rise in pH).

272 the dyads assemble to create an alternating bilayer type structure, with horizontal alternating alky

273 oups with linear p-alkoxyphenyl units led to bilayer-type smectic mesophases, wedge-shaped units resu

274 rane proteins embedded in their native lipid bilayer, typically by retracting the cantilever at a con

275 To explore this, a bilayer unzipping technique was designed to uncouple the

276 bedded in synthetic liquid crystalline lipid bilayers using two-dimensional J-resolved NMR spectrosco

277 tably inserted into the outer leaflet of the bilayer, verapamil dynamically flip flops between the bi

278 ionally well-defined large unilamellar lipid bilayer vesicles to study the impact of MGDG on light ha

279 PIP(2) immobilization also occurred when the bilayer was supported on a protein surface rather than g

280 ng status of reconstituted hairpins in lipid bilayers, we found that the E217G hairpin exhibits an al

281 Simulations of phase-separated bilayers were used to predict two sources of contrast be

282 cellular domains tethered to supported lipid bilayers, were studied using a combination of dynamic si

283 is hampered by Peierls instability, or other bilayers, where doping by applied voltage is required, r

284 r with that occurring in the edge state of a bilayer, which is terminated by ferromagnetic iron clust

285 distinct alterations in phosphatidylcholine bilayers, which are used in this work as models for the

286 model by studying angle-aligned WSe(2)/WS(2) bilayers, which form moire superlattices(6) because of t

287 For instance, asymmetric flat bilayers, whose specific areas in each leaflet are match

288 is functionalized by embedding an imprinted bilayer wire-grid polarizer within the CQDs.

289 ial of this technique, diffraction gratings, bilayer wire-grid polarizers, and resonant metal mesh lo

290 This leaves a lipid bilayer with a relatively high density of membrane prote

291 ring in the edge state of a pristine bismuth bilayer with that occurring in the edge state of a bilay

292 Cell membranes mainly consist of lipid bilayers with an actively regulated composition.

293 partitioning of the fluorophores into lipid bilayers with different lipid compositions.

294 near-0 degrees -twist-angle MoSe(2)/MoSe(2) bilayers with large rhombohedral AB/BA domains(15) to di

295 e disc mediated formation of supported lipid bilayers with membrane proteins represents an attractive

296 incorporation of membrane proteins in lipid bilayers with sufficiently high concentration and contro

297 iate the formation of supported phospholipid bilayers with two different types of membrane proteins,

298 ylsiloxane polymer supports, producing "soft bilayers" with physiological levels of mechanical resist

299 st that lipids can favorably assemble into a bilayer within the larger CALHM2 pore, but not within CA

300 ily can successfully insert into a synthetic bilayer without the need for translocon insertase appara