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1 g that LvgA recognizes more than one type of binding motif.
2 sphorylatable residues within a reported SH3-binding motif.
3 ed design starting from a known kinase hinge binding motif.
4 ing to position E23 serve as the core of the binding motif.
5 angement of the nucleosomal array around the binding motif.
6 mplification via an intracellular calmodulin-binding motif.
7 rrelated with the NR4A3 transcription factor binding motif.
8 tructural adjustment of the periplasmic TonB-binding motif.
9 of KRAS4b, which might represent a novel CaM-binding motif.
10 arvesting complexes, including a chlorophyll-binding motif.
11 ecognition cap and hydroxamic acid as a zinc-binding motif.
12 eraction was mediated by an N-terminal UAP56-binding motif.
13 in in Sgo1 in close proximity to the cohesin-binding motif.
14 ctivation of a reporter with a FOXP2-derived binding motif.
15 encode proteins with a helix-turn-helix DNA-binding motif.
16 evealing a new role for this protein-protein binding motif.
17 e MSL complex by de novo acquisition of this binding motif.
18 died using short peptides recapitulating the binding motif.
19 reporter gene due to the absence of a Keap1-binding motif.
20 a a nonclassical, potentially catalytic zinc-binding motif.
21 ient for binding and defines the minimal CaM-binding motif.
22 protein/transcriptional coactivator with PDZ-binding motif.
23 nserved K-segment, proposed to be a membrane-binding motif.
24 ordered state and lacks any recognizable RNA-binding motif.
25 f A, which we previously identified as a CDK-binding motif.
26 nsight into this less-well-understood 14-3-3 binding motif.
27 ors due to biases in CpG enrichment in their binding motif.
28 e Walker A sequence, a well-known nucleotide-binding motif.
29 n CpG enrichment of the transcription factor binding motif.
30 s 2 to 8 of the N-proximal arginine-rich RNA binding motif.
31 2, which contains a conserved Y(X)4LPhi IF4E-binding-motif.
32 er modulated by affinity and position of B56 binding motifs.
33 based on their size, polarity, and specific binding motifs.
34 as is enrichment for several splicing factor binding motifs.
35 n and subclass-enriched transcription factor binding motifs.
36 t DNA repair proteins that contain ubiquitin-binding motifs.
37 inding of SMAD1/5 and a requirement for SMAD binding motifs.
38 inder threshold followed by a list of glycan-binding motifs.
39 ignificantly with other transcription factor binding motifs.
40 eins featured, length distributions, and HLA-binding motifs.
41 ed by adding either dimerization or membrane-binding motifs.
42 many TGF-beta1-responsive genes possess p53 binding motifs.
43 clin F via their conserved N-terminal cyclin binding motifs.
44 within coding regions near known amoxicillin binding motifs.
45 the binding of suramin to the "AT-hook" DNA-binding motifs.
46 exes and transcription factors competing for binding motifs.
47 enriched for hypoxia-inducible factor family binding motifs.
49 in their overall architecture and phosphate binding motif, a lack of sequence identity and some fund
50 s all possess two spatially separated nickel-binding motifs: a variable C-terminal histidine tail and
51 periment, viz., the recoverability of the TF binding motif, accuracy of TF-DNA binding detection, the
53 protein/transcriptional coactivator with PDZ-binding motif activation/expression, dedifferentiation,
54 bstantially following injury to reveal STAT3 binding motifs adjacent to genes that regulate essential
55 and physiological studies identify a lipid A-binding motif along the periplasmic leaflet of the inner
56 n each species to evolve hundreds of de novo binding motifs along the neo-X, including expansions of
57 ively charged residues adjacent to the lipid binding motif also resulted in autophagy inhibition, sug
58 host protein Keap1, MLAV VP24 lacks a Keap1-binding motif and fails to activate this cytoprotective
59 n of the E3 ligase complex, such as the zinc-binding motif and N- and C-terminal regions of the prote
60 ncluding expression quantitative trait loci, binding motif and transcriptome analyses, and biological
61 explain the immunodominance of the receptor-binding motif and will guide the design of COVID-19 vacc
62 d mixture model for monomeric and dimeric TF-binding motifs and an expectation maximization algorithm
63 h to model nonlinear interactions between TF binding motifs and chromatin accessibility information u
64 n improved technology for discovering HLA-II binding motifs and conducted a comprehensive analysis of
65 in accessibility surrounding IRF4 and BLIMP1 binding motifs and epigenetic remodeling of IL21R and PR
67 NA sequences containing their respective DNA-binding motifs and identify preferential motif arrangeme
68 vestigate the effect of transcription factor binding motifs and local sequence context on p53-bound C
69 t contain at least one of the 25 specific TF binding motifs and located near bovidae-to-cattle lineag
70 , such as combinatorial transcription factor binding motifs and long non-coding RNAs, that potentiall
71 phosphorylation in cells suggest that kinase binding motifs and phosphorylation sites line up to maxi
72 ched in PHYTOCHROME-INTERACTING FACTOR (PIF)-binding motifs and the transcriptome of pp7l-1 resembled
73 through suramin binding to the "AT-hook" DNA-binding motifs and therefore preventing HMGA2 from bindi
75 splicing factor, zinc finger CCCH-type, RNA binding motif, and Ser/Arg rich 2/Rough endosperm 3 (RGH
76 ociates with Flamingo via its C-terminal PDZ binding motif, and we show that Snx27 is essential for n
77 nome-wide, at predicted transcription factor binding motifs, and across human epigenomic domains.
78 modynamic basis for different linker histone binding motifs, and details their physical and chemical
79 R, pS118-ER sites were enriched in GRHL2 DNA binding motifs, and estrogen treatment increased GRHL2 r
80 ionally essential activator protein 1 (AP-1)-binding motifs, and responds to injury, but it cannot re
81 H1 and EZH2 restricted accessibility to AP-1-binding motifs, and their absence promoted a regulatory
83 type cytochromes with a contracted CXCH heme-binding motif are present throughout the bacterial and a
84 ndom copolymers containing dipicolylamine as binding motifs are designed to coordinate type-3 Cu site
85 ngaged in none, and the intracellular GTPase-binding motifs are essential for trajectory choice and s
86 genome-wide analyses showing that their DNA-binding motifs are highly overrepresented in regions tha
91 fic classes of CTCF and transcription factor binding motifs are similarly correlated with ASM in canc
93 nd TAZ (transcriptional coactivator with PDZ-binding motif) are regulators of single-cell volume.
94 gically inspired hydroxamate groups and zinc-binding motifs assembles through concurrent Fe(3+) and Z
96 , zonula occludens-1 protein (PDZ) consensus binding motif at its C-terminus and binds to PDZ domain
97 on, CRISPRi/dCas9-mediated blocking of Ash2l-binding motifs at these super-enhancers also prevents OS
98 ch repair protein MutL has an internal clamp-binding motif, but its interaction with the beta-clamp h
100 t the ligands still bind at the noncanonical binding motif, but with fewer hydrogen-bonding interacti
102 he absence of any sequence similarity to the binding motif, can DNA shape still increase binding prob
103 signal, conferred by low affinity pMad/Medea binding motifs, can contribute to the specification of B
104 l-induced" pocket and possess bicyclic hinge-binding motifs capable of forming more than one hydrogen
105 on to the genome-wide accessibility of their binding motifs classifies them as predominantly openers
106 ome analysis revealed a distinct DQ6 peptide-binding motif compared with the susceptible DQ2/8 molecu
107 l of these proteins contain the typical heme-binding motif CXXCH and require the Ccm proteins for mat
108 peptide mimetic derived from the Na(V)1.8 WW binding motif decreased sodium currents, reduced Na(V)1.
110 lyMDB provides data visualization and glycan-binding motif discovery for 5203 glycan microarray sampl
111 tivated transcriptional coactivator with PDZ-binding motif-driven GBM mouse model, neutrophils coinci
113 but cannot describe how proteins with clamp-binding motifs embedded in structured domains are recogn
114 (ROK) family, but many lack the canonical Zn-binding motif expected for this function, and the sugar-
115 o PSD-95 was very weak, and deleting the PDZ-binding motif failed to alter synaptic trafficking.
117 intracellular N terminus, which contains the binding motif for endogenous Src tyrosine kinase that co
118 confirmed by the identification of a YYIYVI-binding motif for HSC70 that spans residues 83-88 of the
119 ession and identified a transcription factor binding motif for LRF near these modifications in both c
121 demonstrate that E2F1 acetylation creates a binding motif for the bromodomains of the p300/KAT3B and
123 te assembly uncovered a transcription factor-binding motif for ZNF263, a C2H2 zinc finger protein.
124 t the associated genetic loci resided within binding motifs for adipogenic transcription factors (e.g
125 tes are significantly enriched for predicted binding motifs for critical epidermal transcription fact
126 ncluding a mouse-specific gene set, and bear binding motifs for critical regulators of spermatogenesi
127 aries, we identified and refined the peptide binding motifs for each of the four molecules and found
128 associated with chromatin sites that harbor binding motifs for IKAROS and EBF1 and physically associ
129 TAC") does so by rediscovering ab initio the binding motifs for known regulators and some unknown one
130 ytes compared to wild type were enriched for binding motifs for NF-kappaB and AP-1, transcription fac
136 LOP against other MEA methods in identifying binding motifs found enriched in differentially active r
137 oves the ability to call enrichment of ISGF3 binding motifs from differential acetylation ChIP-seq da
140 lytic motif (DPP(Y/F)) as well as the AdoMet-binding motif (FXGXG) by site-directed mutagenesis aboli
141 N-(4-(p-methoxyphenyl)butanoyl)-Gly albumin-binding motifs generated HTK03121 and HTK03123, respecti
145 an SAC, since the relevant PLK1 and PP2A-B56 binding motifs have coevolved in the same region on MADB
146 MD1 requires Fe(II) and the integrity of its binding motif His-X-Asp, which is conserved in Fe-depend
147 thermore, two important transcription factor-binding motifs, hypoxia-inducible factor 2alpha (HIF2alp
148 predict that a few residues on the receptor-binding motif, i.e., 452, 489, 500, 501, and 505, have h
149 most frequently mutated ETS, AP-1, and NF-kB binding motifs, implicating these motifs as governors of
150 coviruses detected to date, and its receptor-binding motif, important for specificity to human ACE2 r
151 2 interacts with HP1 through a conserved HP1-binding motif in its N-terminus, which in turn leads to
152 o investigate the contribution of this STAT1-binding motif in NiV-mediated disease, we produced rNiVs
153 otif C, which has been indicated as a cyclin binding motif in other contexts, appears to be relativel
155 we identified a putative EF-hand-like Ca(2+) binding motif in the carboxyl terminal region of BTV non
156 We identified a consensus glycosphingolipid-binding motif in the extracellular juxtamembrane domain
158 tations to the S-adenosyl-l-methionine (SAM) binding motif in the nsp14 abolished the G-N-7 MTase act
159 niques to confirm the predicted Walker-B ATP-binding motif in the phage lambda motor and to investiga
160 through YAP association with the TEA domain-binding motif in the promoter region of inflammatory cyt
162 g a conserved cysteine within a 3His/1Cys Zn-binding motif in TlpD that inactivates the chemotransduc
163 MEA method that determines enrichment of TF binding motifs in a list of scored regulatory regions, w
166 lf4; reflecting a genome-wide paucity in ETS-binding motifs in Etv6 genomic targets, Klf4 then recrui
168 tool to analyze paired transcription factor binding motifs in the promoters of cell type-specific ge
169 egulated genes preferentially contained NF-Y-binding motifs in their proximal promoters, and notably
171 tructure by NMR identified a linear c-di-GMP-binding motif, in which a self-intercalated c-di-GMP dim
172 ighly concordant set of transcription factor binding motifs, including motifs for the GC receptor cof
173 the presence of several transcription factor binding motifs, including RBPJ1, EGR1, and SOX4, suggest
174 n or disruption of TF (transcription factor)-binding motifs, inferred from alternative alleles at the
175 ucture revealed an EF domain with two Ca(2+)-binding motifs inserted within the catalytic domain.
176 revealed that thyroid hormone receptor 1beta-binding motif insertions have evolved in several genera
177 halamic T(3), driven in part by the receptor-binding motif insertions in some cricetid genomes, contr
178 within the regulatory domain, only the clamp binding motif is required for the interaction between th
180 along with the presence of a catalytic zinc-binding motif, it is possible that the identified protei
181 onstrate that the XLF tail along with the Ku-binding motif (KBM) at the extreme C-terminus are requir
183 howed that mutation of one of its 2 putative binding motifs markedly diminished T cell activation aft
184 le two classes of extra-terminal (ET)-domain binding motifs mediate acetylation-independent interacti
185 ated SF1 sites and potentially rescuing GATA binding motifs might play a role in the development of P
186 s were identified that interact with the PDZ-binding motif of Claudin-2 in liver metastatic breast ca
190 utively inhibits I(Kv1.5) Disrupting the Src-binding motif of Kv1.5 through N-terminal truncation or
192 conformation of the minimal pseudo-dipeptide binding motif of pepstatin A, a microbial oligopeptide i
193 n of tyrosine-1229 (L1-Y1229) at the ankyrin binding motif of the L1 cytoplasmic domain, leading to t
194 ous mutations to the common N-terminal STAT1-binding motif of the NiV P, V, and W proteins affected t
196 understand ANT1 functions, we determined the binding motif of ZmANT1 and then showed that ZmANT1 bind
199 hat O-glycans positioned within the receptor binding motifs of members of the neuropeptide Y and gluc
201 hromatin remodeling in regions enriched with binding motifs of the pioneer transcription factor PU.1.
202 Finally, we demonstrate that the nucleotide-binding motifs of the predicted atypical kinase Mcp2 are
204 rmore, tissue-specific NFR were enriched for binding motifs of transcription factors related to tissu
207 or 6 (GATA-6) and NF-kappaB to their cognate binding motifs on CAV1, CAV2, and CAV3 promoters in obst
208 oacervate to deliver IL-12, in which heparin-binding motifs on IL-12 allow for its effective encapsul
210 ed rNiVs with complete deletion of the STAT1-binding motif or the Y116E mutation for ferret challenge
211 may introduce aberrant transcription factor binding motifs or enhancer hijacking by structural varia
212 ive alleles altered the transcription factor binding motifs or histone modifications, indicating the
214 ng the flexibility of the linker between two binding motifs, our results suggest that the conformatio
215 information about transcription factor (TF) binding motifs, patterns of covalent histone modificatio
218 d PDZ domain and a highly conserved aPKC PDZ-binding motif (PBM) that is required in the context of t
221 Replacement of the imidazopyridine hinge binding motif present in the initial compounds of this s
222 ays showed that NKX2.1 binds in vitro to NKX binding motifs present in the neuronal Pomc enhancers nP
226 how that following genotoxic stress, the RNA-binding motif protein 7 (RBM7) stimulates RNA polymerase
227 unprecedented finding that the conserved RNA-binding motif protein, RBM24, positively controls Sox2 m
228 ng the pathogenic R636S variant of human RNA-binding motif protein-20 (RBM20), we discovered that RNP
229 e that overlaps with the human ACE2 receptor binding motif providing a structural basis for its neutr
230 he nSH3/cSH3 domains have distinct preferred binding motifs: PxxPxR for nSH3 and PxxxRxxKP for cSH3 (
231 nce of 2019-nCoV RBD, including its receptor-binding motif (RBM) that directly contacts ACE2, is simi
233 48, adjacent to the canonical phiX(D/E) Cul3-binding motif, reduced affinity of A55BB for Cul3-NTD by
234 tide (SBP), contains two potential sulfatide-binding motifs represented by two consecutive polybasic
235 of the light-harvesting complex chlorophyll-binding motif required for chlorophyll binding were muta
236 scription Factors (TFs) to their cognate DNA binding motifs requires a precise control over nucleosom
238 serine proteases, its carboxy-terminal CARD-binding motif restrained the activation of pro-caspase-1
239 cs (iTRAQ) and an in silico analysis of SigF binding motifs revealed possible targets/pathways under
242 hat CoV-2 RBD does not bind to ACE2 with the binding motif shown in experiments, but it rotates becau
244 ompete identifies a GC-rich region as SERBP1-binding motif; subsequent genomic and functional analyse
245 f GPCRs contain at least one putative 14-3-3 binding motif, suggesting GPCR/14-3-3 association could
247 egions were enriched in transcription factor binding motifs, suggesting a potential gene regulatory r
248 1 proteins also carry multiple "AT-hook" DNA-binding motifs, suramin is expected to inhibit HMGA1-DNA
250 P) and transcriptional co-activator with PDZ-binding motif (TAZ) are increased in many human cancers,
251 homolog transcriptional coactivator with PDZ-binding motif (TAZ) are key effectors of the Hippo pathw
252 AP) and transcriptional coactivator with PDZ-binding motif (TAZ) are the key mediators of the Hippo s
253 AP) and transcriptional coactivator with PDZ-binding motif (TAZ) in hepatocytes to facilitate cell-ce
254 sociated protein (YAP) and its paralogue PDZ-binding motif (TAZ) with associated decline in activatio
255 AP) and transcriptional coactivator with PDZ-binding motif (TAZ), the key downstream transcriptional
256 ap) and transcriptional coactivator with PDZ-binding motif (Taz), two transcriptional coactivators kn
257 (YAP1)/transcriptional coactivator with PDZ binding motif (TAZ)-dependent, irreversible fibrosis and
261 AP) and transcriptional coactivator with PDZ-binding motif (TAZ, also called WWTR1), the main downstr
263 , Frizzled4, which contains a C-terminal PDZ-binding motif that can bind to Dlg1 PDZ domains, appears
264 that the WD40 domain of FBXW7 is a novel PAR-binding motif that facilitates early recruitment of FBXW
265 d C-terminal tail of NHERF1 has a type 1 PDZ-binding motif that interacts weakly with the proximal, s
266 with the beta-clamp harbor a conserved clamp-binding motif that is often found in extended regions.
267 cysteine and histidine residues form a zinc-binding motif that is required for HBx function.IMPORTAN
268 Mutational analyses identified a FxxxLxxxK binding motif that is shared by VpdB and SidH, but not b
269 trafficking and signaling, and provide a WDD-binding motif that might be used to identify additional
270 ortantly, we show that the CArG-box-like DNA-binding motifs that are bound by PHE1 have been distribu
271 e three molecules in the system contains two binding motifs that can interact with each other and are
274 affect RNA-protein interactions from outside binding motifs through altered RNA secondary structure.
276 ikely interacts with Aer2 via conserved CheD-binding motifs to make Aer2 a better methylation substra
277 tions of A20's zinc finger 7 (ZF7) ubiquitin-binding motif uniformly developed digit arthritis with f
278 o steric immobilization of the proximal heme-binding motifs upon complex formation, a finding that ma
279 protein/transcriptional coactivator with PDZ-binding motif via rho kinase, which were shown to increa
281 n-regulated by ethylene in shoots, and a DNA binding motif was identified that is important for this
282 eCh CAB domain with a functional chlorophyll-binding motif was retained in all currently known cyanob
283 as enriched in multiple transcription factor binding motifs, was bound by an important transcription
285 -binding domain nor the clathrin heavy chain-binding motif were needed for virus infection, whereas t
286 FrtR protein was purified, and conserved DNA binding motifs were determined using electrophoretic mob
287 profiled >40 HLA-II alleles and showed that binding motifs were highly sensitive to HLA-DM, a peptid
288 ription factor (TF) binding by mutating a TF binding motif, which in turn may affect the activity of
289 minal domain (CT) of GluD1 has a classic PDZ-binding motif, which is critical for the synaptic traffi
290 rring contracted Cys-Lys-Cys-His (CKCH) heme-binding motif, which is encoded in the hydrazine synthas
291 n, we also identified differences in peptide binding motifs, which could explain the observed variati
292 While it is clear that changing a protein binding motif will alter protein binding, it has been sh
293 The cocrystal structure of the W C-terminal binding motif with 14-3-3 provides only the second struc
295 ized in DPC-2 shared certain similar peptide-binding motifs with DPC-1 or DPC-3 alleles, but signific
296 at can act as a template to display multiple binding motifs with precise spatial pattern-recognition
297 Structural analyses revealed an EB-like +TIP-binding motif within the capsid major homology region (M
300 near motif known as the zDHHC ankyrin repeat-binding motif (zDABM) in SNAP25 ((112)VVASQP(117)), whic