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1 RPLP1/2 in multi-pass transmembrane protein biogenesis.
2 s a key role in outer membrane protein (OMP) biogenesis.
3 of bacteria recently implicated in ribosome biogenesis.
4 ecruitment to the nucleolus and 60S ribosome biogenesis.
5 in mitochondrial iron-sulfur (Fe-S) cluster biogenesis.
6 nship between TORC1 inactivation and vacuole biogenesis.
7 levance of each of these steps of telomerase biogenesis.
8 es of previously unknown function in surface biogenesis.
9 a broader role in polytopic membrane protein biogenesis.
10 s pattern primarily associated with ribosome biogenesis.
11 otein ESCRT complex participating in exosome biogenesis.
12 during the autocatalytic process of cofactor biogenesis.
13 n part, through inhibition of let-7 microRNA biogenesis.
14 related compounds, and based on their common biogenesis.
15 c mechanisms that regulate membrane flux and biogenesis.
16 RNA is preserved due to its role in ribosome biogenesis.
17 l platform for the completion of overall MRC biogenesis.
18 rwood as a new model for the study of lignin biogenesis.
19 te transitions between these two modes of PG biogenesis.
20 nges seen across indicators of mitochondrial biogenesis.
21 ike AC9, ERK7 is required for apical complex biogenesis.
22 ur results lead to a mechanistic model of LB biogenesis.
23 iption, which is a critical step in ribosome biogenesis.
24 ols nicotinic acetylcholine receptor (nAChR) biogenesis.
25 ates TFEB, the master regulator of lysosomal biogenesis.
26 ed role of staphylococcal lipoproteins in EV biogenesis.
27 cket collar (FPC), which is essential for FP biogenesis.
28 h is generally linked to defects in ribosome biogenesis.
29 stent with a phenotype of perturbed ribosome biogenesis.
30 on allowing for stringent control of peptide biogenesis.
31 vide a source of lipids during autophagosome biogenesis.
32 ing an unexpected RILP role in autophagosome biogenesis.
33 ic activity that is essential for apicoplast biogenesis.
34 ts precursor and is thus required for signal biogenesis.
35 irst dual inhibitor of AChE and microRNA-15b biogenesis.
36 was required to abrogate its function in 60S biogenesis.
37 oporin essential for interphase nuclear pore biogenesis.
38 R-18a, and miR-20a, thereby inhibiting their biogenesis.
39 n of ribosomal DNA (rDNA) genes and ribosome biogenesis.
40 fission-fusion, mitophagy, and mitochondrial biogenesis.
41 of its target genes, and impaired complex I biogenesis.
42 f genes involved in translation and ribosome biogenesis.
43 ption is generated by aberrant cell envelope biogenesis.
44 y PHY-mediated signalling and proper plastid biogenesis.
45 round centriolar MTs and promoting centriole biogenesis.
46 oter-proximal RNA polymerase II during piRNA biogenesis.
47 ane fusion during nuclear pore complex (NPC) biogenesis.
48 known about the regulation of apical complex biogenesis.
49 f platelet size in flow-accelerated platelet biogenesis.
50 bile heme in the regulation of mitochondrial biogenesis.
51 e, suggesting GPI7 is required for cell wall biogenesis.
52 I (Pol I) is the first key step of ribosome biogenesis.
53 le assembly, primarily dedicated to ribosome biogenesis.
54 that colocalizes genes involved in ribosome biogenesis.
55 oss of HSCB results in impaired Fe-S cluster biogenesis, a defect in RBC hemoglobinization, and the d
56 nt of new antibiotics that disrupt cell wall biogenesis, a process essential to the survival of bacte
57 hanolamine (PE), a critical step in membrane biogenesis and a potential target for development of ant
59 r EB (TFEB), a master regulator of lysosomal biogenesis and autophagy(4,5), is phosphorylated by mTOR
60 aster transcriptional regulator of lysosomal biogenesis and autophagy-is activated during the lysosom
68 aveolin-1 (Cav1) centrally regulates exosome biogenesis and exosomal protein cargo sorting through th
70 unctions as a master controller of lysosomal biogenesis and function during lysosomal stress, control
72 ranscription, nucleotide synthesis, ribosome biogenesis and function, as well as lipid metabolism.
73 tional regulators of postnatal mitochondrial biogenesis and function, serve a role in the broader car
74 Here, we review the latest findings on the biogenesis and functions of EVs from Gram-positive bacte
75 he fundamental mechanisms underpinning cilia biogenesis and functions remain only partly understood.
76 s; in turn, the nucleus fine-tunes lysosomal biogenesis and functions through transcriptional control
77 ed by mutations in the mitochondrial cristae biogenesis and fusion protein optic atrophy 1 (Opa1), re
80 alyses revealed an increase of mitochondrial biogenesis and global translational rate in Lmna (LCS/LC
82 ered, to what extent ABS involves in circRNA biogenesis and how it is regulated in different human ti
83 the spationumerical regulation of flagellar biogenesis and implies that flagellar assembly transcrip
85 opose that SEIP-1 may maternally regulate LD biogenesis and lipid homeostasis to orchestrate the form
89 show that shear stress favours mitochondrial biogenesis and metabolic reprogramming to ensure energy
90 Mitochondria undergo dynamic fusion/fission, biogenesis and mitophagy in response to stimuli or stres
93 layers and mechanisms involved in peroxisome biogenesis and peroxisome degradation, very few studies
94 anscriptional programs that promote ribosome biogenesis and protein synthesis in cells stimulated to
97 eceptor from ILC precursors interrupted ILC3 biogenesis and rendered newborn mice susceptible to pneu
99 LP integrates the processes of autophagosome biogenesis and retrograde transport to control autophagi
101 es have described mechanisms responsible for biogenesis and secretion of SGs, but how SGs mature rema
102 (1)/S(2) subunits, which is processed during biogenesis and sets this virus apart from SARS-CoV and S
103 he EGRESS complex as key players in lysosome biogenesis and shed light on the molecular etiology of B
104 smRNAs play a central role in modulating JA biogenesis and signaling during hemibiotrophic fungal in
105 dolysosomal trafficking is essential for WPB biogenesis and sought to identify BLOC-2-interacting pro
106 recently that the mechanisms underlying the biogenesis and specificity of m(6)A modification in cell
107 subcomponents and proteins implicated in the biogenesis and stability of the apical complex and, in t
110 ing that vitamin B12 regulates mitochondrial biogenesis and then affects mitochondrial fission via ch
111 or 5' tRNA fragment control of noncoding RNA biogenesis and, consequently, global chromatin organizat
117 l catabolic genes, impairment of chloroplast biogenesis, and reduction of carotenoid synthesis in lea
118 ER localization signal during active protein biogenesis, and that alpha(1D)-AR N-terminal glycosylati
119 r RP-mRNAs, enhancing RP synthesis, ribosome biogenesis, and the overall protein synthesis in migrato
121 e biosynthesis and iron-sulfur cluster (ISC) biogenesis are two major mammalian metabolic pathways th
122 iesterase 5 inhibitor, induced mitochondrial biogenesis as measured by increased uncoupled oxygen con
123 light-responsive miR-211 controls lysosomal biogenesis at the beginning of light-dark transitions in
124 lay a role with select SEIPIN isoforms in LD biogenesis at the ER, and additional experimental eviden
125 logical course of autophagy in neurons, from biogenesis at the synapse to degradation in the soma.
127 clear protein that is not required for piRNA biogenesis but is essential for piRNA-directed TE de nov
129 the absence of complex III blocks complex I biogenesis by preventing the incorporation of the NADH m
130 r degradation and thereby controls centriole biogenesis by restraining HsSAS-6 recruitment to the mot
131 gosomal pathway and the control of lysosomal biogenesis by TFEB, thus ensuring coordinated activation
132 f essential genes involved in outer membrane biogenesis can also trigger T6SS activation in P. aerugi
133 t with a role in multi-pass membrane protein biogenesis, cells lacking different accessory components
134 ile proteins that play critical roles in the biogenesis, cellular localization and transport of RNA.
135 lational programs, and the impaired ribosome biogenesis checkpoint (IRBC) provide a foundation for th
141 the same RP gene can drive similar ribosome biogenesis defects yet still have markedly different dow
142 RNA helicases play various roles in ribosome biogenesis depending on the ribosome assembly pathway an
144 nance (dyskeratosis congenita), and ribosome biogenesis (Diamond-Blackfan anemia, Shwachman-Diamond s
145 d to change at the RNA level (e.g., ribosome biogenesis) did not do so at the protein level, and vice
146 stages of protein biosynthesis and ribosome biogenesis during both stages of hibernation that sugges
147 localization as a key regulator of ribosome biogenesis during cell migration and demonstrate a role
150 nds have been reported, the details of their biogenesis, especially the mechanisms for assembly of di
151 At night retinas undergo a mitochondrial biogenesis event, corresponding to an increase in the nu
153 fy apum23-4, a mutant allele of the ribosome biogenesis factor (RBF) gene ARABIDOPSIS PUMILIO23 (APUM
155 , where multiple ribosome-associated protein biogenesis factors (RPBs) direct nascent proteins to dis
157 proteins with demonstrated roles as ribosome biogenesis factors; knockdown of GLTSCR2 impairs maturat
158 e regulatory components that control lipid A biogenesis, focusing on the rate-limiting step performed
159 ires the induction of autophagy and lysosome biogenesis for the efficient recycling of macromolecules
160 of the mechanisms involved in autophagosome biogenesis has increased substantially during the last 2
161 external cues by stimulating beige adipocyte biogenesis; however, the developmental origin and pathwa
162 echanisms of rcDNA deproteination and cccDNA biogenesis.IMPORTANCE The covalently closed circular DNA
163 we recast mechanisms controlling peroxisome biogenesis in a framework that integrates inference from
166 sembly intermediates (AIs) of complex I (CI) biogenesis in Drosophila will enable the characterizatio
167 rther affirm the involvement of Fe-S cluster biogenesis in erythropoiesis and hematopoiesis and defin
168 r contributions toward understanding betaOMP biogenesis in Gram-negative bacteria and in mitochondria
170 with epigenetic regulation of mitochondrial biogenesis in human placenta in a fetal sex-dependent ma
173 us Bccip loss was insufficient to impair 60S biogenesis in mouse embryo fibroblasts, but a profound r
174 s draw new parallels between snRNA and piRNA biogenesis in nematodes and provide evidence of a role f
177 that it has an essential role in basal body biogenesis in T. brucei Further investigation of the fun
178 during folding in vivo Current models of OMP biogenesis in the cellular environment are still in flux
181 We report that 10 uM DOX blocks apicoplast biogenesis in the first cycle and is rescued by isopente
182 explains the strong acceleration of platelet biogenesis in the presence of an external flow, which we
183 show differences in hybrid and WT RsRubisco biogenesis in tobacco correlated with assembly in Escher
185 ulating muscle stem cells involved in muscle biogenesis, in addition to affecting signalling pathways
186 enomic feature annotation related to circRNA biogenesis, including length of introns flanking circula
189 for biological processes such as amino acid biogenesis, iron-sulfur cluster formation, and redox hom
194 sised that successful initiation of phasiRNA biogenesis is conservatively maintained, while phasiRNA
204 identified to participate in outer-membrane biogenesis: LPS transport via the Lpt machine, and phosp
205 ipts encoding protein synthesis and ribosome biogenesis machinery and regulated by the mTOR pathway.
206 n, an essential component of the iron-sulfur biogenesis machinery, in mitochondria from TAZ-KO mouse
210 that has been suggested to regulate collagen biogenesis, muscle development, ciliogenesis, and variou
211 ensitivity and protein synthesis to the tRNA biogenesis mutants, but not to the mutant reducing amino
213 eal a key role of DSTYK in notochord vacuole biogenesis, notochord morphogenesis and spine developmen
214 cs drives a significant increase in ribosome biogenesis, nucleolar expansion and cell growth in a man
219 hosphoryl lipid A, MPLA) displayed increased biogenesis of bacterial outer membrane vesicles (OMVs).
220 ucial role of EphB1/Cav-1 interaction in the biogenesis of caveolae and in coordinating the signaling
223 Here, we review recent insights into the biogenesis of eRNAs and the mechanisms underlying their
227 bation of cellular machinery involved in the biogenesis of intralumenal vesicles at endosomes (the so
228 ells ensure this asymmetry by regulating the biogenesis of lipid A, the conserved and essential ancho
230 he Drosophila CLP1 orthologue, cbc, promotes biogenesis of mature tRNAs and circularized tRNA introns
233 Genetic deletion of XPO5 compromises the biogenesis of most miRNAs and leads to severe defects du
234 al skeleton segmentation due to dysregulated biogenesis of notochord vacuoles and notochord function.
235 of the first two steps are also required for biogenesis of numerous essential cytosolic and nuclear F
236 ther subunit of the PAT complex show reduced biogenesis of numerous multi-spanning membrane proteins.
237 Notably, factors in the ER required for the biogenesis of peroxisomes also impact the formation of l
239 elated organelle-2 (BLOC-2) functions in the biogenesis of platelet dense granules and melanosomes, w
240 a subset of nuclear genes with roles in the biogenesis of respiratory complex I and the mitoribosome
244 ct the spatiotemporal events involved in the biogenesis of the LBs at the genetic, molecular, biochem
246 s expression and provides a platform for the biogenesis of the nascent transcripts emanating from the
249 ained a substantial amount of attention, the biogenesis of these extracellular RNA fragments remains
252 n induced by gene inactivations of lysosomal biogenesis or acidification factors causes vitamin B12 d
254 infertility but does not affect either piRNA biogenesis or the localization of MIWI2 to the nucleus.
256 Fe-2S clusters from the chloroplastic 2Fe-2S biogenesis pathway to different cytosolic and chloroplas
257 ly of SGs and the canonical dsRNA-induced SG biogenesis pathway, because RLBs did not require protein
258 r EB (TFEB), a master regulator of lysosomal biogenesis, plays an essential role in the lysosomal exo
259 y to tRF-GG, and are required for Cajal body biogenesis, positioning these proteins as strong candida
260 -small size and intricate post-translational biogenesis preclude the use of simple genetic tagging in
261 but essential role in the regulation of LPS biogenesis, presents a new structural basis for the sele
263 e training period, suggesting that ribosomal biogenesis regulates the dose-response relationship betw
268 n, our current understanding of tetrapyrrole biogenesis represents a remarkable biochemical milestone
273 gnificant functions associated with ribosome biogenesis, rRNA processing, ribosome binding, GTP bindi
274 Exercise training-mediated mitochondrial biogenesis, running endurance, and beneficial glycemic e
276 chemotherapy or radiation therapy, ribosome biogenesis stress, and possibly inflammation may increas
277 to DRE2, a key protein of the cytosolic Fe-S biogenesis system, and propose that the availability of
278 S proteins, as well as to the cytosolic Fe-S biogenesis system, and that uncoupling this process trig
280 uncover various genes involved in EV subtype biogenesis that play a regulatory role in RNA transfer.
281 entifies mechanisms of V-ATPase assembly and biogenesis that rely on the integrated roles of ATP6AP1,
282 cNHEJ-independent functions during ribosome biogenesis that require the kinase activity of DNA-PKcs
283 onse (UPR(mt)), autophagy, and mitochondrial biogenesis, thereby rescuing the mitochondrial phenotype
284 Pharmacological restoration of lysosomal biogenesis through Ezrin inhibition rescued the miR-211(
285 down inhibits notochord vacuole and lysosome biogenesis through mTORC1-dependent repression of TFEB n
286 wing centriole initiates and times centriole biogenesis to ensure that centrioles grow at the right t
288 le of this therapeutic target, including its biogenesis, trafficking to and from the plasma membrane,
290 lation, mRNA processing and export, ribosome biogenesis, translation initiation, and protein processi
292 rons, Leu negatively regulates autophagosome biogenesis via its metabolite, acetyl-coenzyme A (AcCoA)
293 alpha, the master regulator of mitochondrial biogenesis, we searched for compounds that induce this p
294 n central and energy metabolism and ribosome biogenesis were dysregulated more in physiologically rel
297 of genes involved in autophagy and lysosomal biogenesis, were examined in the context of C. burnetii
298 ular processes, such as splicing or ribosome biogenesis, where they remodel large RNA-protein complex
300 olecular mechanisms underlying autophagosome biogenesis, with a specific emphasis on membrane modelin