ライフサイエンスコーパス: blood meal

1 roxy) and resistance to starvation without a blood meal.

2 enetration into the tick body or through the blood meal.

3 hemoglobin, were preserved in the fossilized blood meal.

4 sweat to select humans as their source for a blood meal.

5 h were subsequently fed with Leishmania in a blood meal.

6 ferent immune evasion strategies to obtain a blood meal.

7 t in human sweat to locate their hosts for a blood meal.

8 emperature stress incurred by drinking a hot blood meal.

9 mit the Plasmodium sporozoite stage during a blood meal.

10 complete their first ovarian cycle without a blood meal.

11 port oogenesis without the requirement for a blood meal.

12 of miR-x2 level was observed 72 hrs after a blood meal.

13 increases in the midgut and fat body after a blood meal.

14 uent spirochete transmission during a second blood meal.

15 d with that of the virus administered in the blood meal.

16 es prior to ingestion by a mosquito during a blood meal.

17 or the activation of egg development after a blood meal.

18 es were ingested by the parasites with their blood meal.

19 nsects seem unaffected by the iron load in a blood meal.

20 preventing activation of this gene before a blood meal.

21 and the target YPP gene Vg, in response to a blood meal.

22 genous mosquitoes, egg maturation requires a blood meal.

23 tive cycle and is activated in response to a blood meal.

24 transgenic mosquitoes from 8 to 24 h after a blood meal.

25 trate the peritrophic matrix surrounding the blood meal.

26 burgdorferi vlsE locus before and during the blood meal.

27 ody tissues of female mosquitoes following a blood meal.

28 cted the host at time points >53 hr into the blood meal.

29 ch presumably assists the fly in obtaining a blood meal.

30 ese antisera were ingested with the infected blood meal.

31 the key event in egg maturation, requires a blood meal.

32 was strongly activated in the fat body by a blood meal.

33 in the fly during excretion of the digested blood meal.

34 nother mammalian host during the tick's next blood meal.

35 ining envelope that completely surrounds the blood meal.

36 is likely primed by bacterial growth in the blood meal.

37 same Vmp present in the previous infectious blood meal.

38 e as well as a lipopolysaccharide-containing blood meal.

39 inogen activators were derived from the host blood meal.

40 throcytes of the vertebrate and the mosquito blood meal.

41 after infection with a LAC virus-containing blood meal.

42 ntibodies in the host as well as in the tick blood meal.

43 response to the increased 20E titer after a blood meal.

44 ined in the mosquito bodies for 7 days after blood meal.

45 ytes by female Anopheles mosquitoes during a blood meal.

46 imic which they bite to obtain an artificial blood meal.

47 dgut tissue after ingestion of an infectious blood meal.

48 quitoes, increases dramatically soon after a blood meal.

49 npredictable moment, when a mosquito takes a blood meal.

50 competing with the tick for nutrients in the blood meal.

51 tor Aedes aegypti, which acquires ZIKV via a blood meal.

52 sion rates in vivo when administered via the blood meal.

53 native microbiota proliferates, following a blood meal.

54 forms into the host's skin while acquiring a blood meal.

55 chetes against threats engendered during the blood meal.

56 ing either component is destroyed during the blood meal.

57 amino acids between mosquito tissues after a blood meal.

58 ding Anopheline mosquito midguts following a blood meal.

59 onally reared Ae. aegypti before and after a blood meal.

60 l site of viral infection after an infective blood meal.

61 acted to human body heat during pursuit of a blood meal.

62 ompensate by taking larger and more frequent blood meals.

63 was reduced, and those feeding took smaller blood meals.

64 mosquitoes to adapt in order to obtain human blood meals.

65 for survival during both larval and nymphal blood meals.

66 ound on clothing that travel to the skin for blood meals.

67 diseases, shows strong preference for human blood meals.

68 hours over the course of their up to 96 hour blood meals.

69 when ingested by Anopheles mosquitoes during blood meals.

70 nfection when fed on patient-derived viremic blood meals.

71 in generalist feeders adventitiously taking blood meals [3, 4], but those cimicid taxa currently con

72 varies of mosquitoes that took an additional blood meal 30 days p.i. and was continuous in mosquitoes

73 Identified blood meals (30%) were from 20 vertebrate species includ

74 cript abundances at five time points after a blood meal, a key event in both reproduction and disease

75 mouthparts and associated structures during blood meal acquisition and salivation.

76 ion to facilitating long-term attachment and blood meal acquisition, gene expression studies of Droso

77 liva is injected into the skin to facilitate blood meal acquisition.

78 athogenicity to vertebrate hosts during tick blood meal acquisition; however, the quantitative nature

79 associated inflammation, allowing successful blood-meal acquisition from hosts.

80 , five of which are possibly associated with blood-meal acquisition, each having cDNA similarity to:

81 tical importance of microRNAs in controlling blood-meal-activated physiological events required for c

82 we uncovered another essential regulator of blood-meal-activated processes, the microRNA miR-275.

83 Consumption of a blood meal activates the vitellogenic phase, which produ

84 s transcribed at a very high level following blood meal activation.

85 s of mosquitoes that did not receive further blood meals after their original oral infection.

86 After an infectious blood meal, AgTreT1 RNA silencing reduces the number of

87 s, carbohydrates, and fatty acids during the blood meal among the three groups of nymphal ticks sugge

88 es the activation of egg development after a blood meal, an adaptation to the unique life style of mo

89 Blood meal analyses from field-captured specimens have s

90 Feeding patterns are assessed via blood meal analyses, reflecting mosquito-host associatio

91 eened for host DNA using DNA barcoding-based blood meal analysis.

92 factor (AaGATAa) that is synthesized after a blood meal and acts as a transcriptional activator of Vg

93 is robust against random degradation of the blood meal and can identify unknown blood remnants month

94 lly synthesize in the tick vector during the blood meal and down-regulate after transmission to the m

95 c activities that promote acquisition of the blood meal and enhance infection with pathogens.

96 Adult females aged 3 days old were given a blood meal and kept separately for individual egg-laying

97 may be occurring during the digestion of the blood meal and not afterwards.

98 heir role in intracellular processing of the blood meal and response to microbial infections.

99 ne evasion when ingested with the infectious blood meal and significantly reduce the prevalence and i

100 are released from the brain in response to a blood meal and stimulate the ovaries to secrete ecdyster

101 rically by offering mosquitoes an infectious blood meal and temporally sampling mosquitoes to determi

102 lting cycle of 4(th) instar nymph, between a blood meal and the ecdysis to 5(th) instar.

103 tes and their critical interactions with the blood meal and the mosquito vector.

104 ear how Plasmodium or other pathogens in the blood meal and their invasion of the midgut epithelium w

105 n occur after adult female mosquitoes take a blood meal and use the nutrients for egg maturation.

106 0) exclusively during the larval and nymphal blood meals and (ii) that transcription of bba74 is brac

107 on the female mosquitoes' ability to obtain blood meals and find water-filled containers in which to

108 parison of mosquito infection via infectious blood meals and intrathoracic injections showed that sfR

109 based on the ecological context of mosquito blood meals and the fine-scale movements of individual m

110 g both ookinete development (day 1 after the blood meal) and oocyst maturation (day 7 after the blood

111 nsu lato), 88.3% were fed, 51.9% had a human blood meal, and 9.2% were sporozoite infected.

112 ed to incorporate components from the flea's blood meal, and bacteria released from the biofilm were

113 reased mRNA abundance in females following a blood meal, and those accumulating transcription product

114 hermsii strains through ingestion during the blood meal, and thus more closely recapitulates pathogen

115 in powder, including six peptides for bovine blood meal; and one peptide for porcine blood.

116 Female mosquitoes that home in on people for blood meals are exquisitely effective at finding us.

117 The model takes a mosquito's blood meal as input and computes the salivary gland spor

118 tic disease, is transmitted during a sandfly blood meal as the parasite is delivered into the dermis.

119 ellow fever mosquito, Aedes aegypti, seeking blood-meals as well as oviposition sites.

120 ene was induced on day 2 after an infectious blood meal, at the time of ookinete to oocyst differenti

121 In response to a blood meal baited with heat and human odorants, pdf muta

122 activation and replication during the tick's blood meal before it is able to infect a host.

123 Of these, 90% had taken a blood meal before their migration, which implies that pa

124 OspD continues during tick digestion of the blood meal but is low or undetectable after the tick has

125 ession of rpoS is induced during the nymphal blood meal but not within unfed nymphs or engorged larva

126 meal) and oocyst maturation (day 7 after the blood meal) but not during sporozoite invasion of the sa

127 raerythrocytic gametocytes are taken up in a blood meal by a mosquito they emerge as gametes and, onc

128 ot exit the RBC until they are taken up in a blood meal by a mosquito.

129 n to humans is suppressed for days after the blood meal by an unknown mechanism.

130 y where blood and microbes ingested with the blood meal come in contact with the tick's internal tiss

131 cretion has been shown as important for both blood-meal completion and pathogen transmission.

132 ting', prolonged feeding, cuticle synthesis, blood meal concentration, novel methods of haemoglobin d

133 to-borne parasite faces when ingested with a blood meal; consequently, understanding the biology of P

134 fects Aedes aegypti mosquitoes that ingest a blood meal containing 8 to 9 log(10) PFU of virus/ml.

135 of the duration of human infectiousness, and blood meals containing high concentrations of DENV were

136 he number of eggs oviposited after the first blood meal decreases with age in all strains; however, t

137 esent work elucidates the molecular basis of blood meal-dependent expression of this mosquito gene, l

138 Tissue-specific expression and blood meal-dependent regulation of Slif are consistent w

139 Host complement in the tick's blood meal did not contribute to protection because the

140 in midgut transcripts in the sand fly during blood meal digestion and that this modulation may be rel

141 r digestive serine proteases, a reduction of blood meal digestion in the midgut, and a decrease in vi

142 that D. variabilis KPI may be important for blood meal digestion in the midgut.

143 aegypti females, the ammonia released during blood meal digestion is partially metabolized to facilit

144 s have to survive the hostile environment of blood meal digestion, escape the blood bolus and attach

145 as proteins putatively directly involved in blood meal digestion, including enzymes involved in oxid

146 ver mosquito Aedes aegypti to interfere with blood meal digestion.

147 ts relevant to the processes associated with blood-meal digestion were analysed and involvement of se

148 investigating the role of the tick midgut in blood-meal digestion, antimicrobial activity or the tran

149 mission as well as pathogen acquisition from blood meal during the tick feeding process.

150 lease of detectable virus particles into the blood meals during feeding events.

151 s in the skin, in addition to affecting tick blood meal engorgement and molting.

152 Our study reveals that blood meals enhance arbovirus replication in mosquitoes

153 mixed population was exposed to an infected blood meal every generation, allele frequencies at the Q

154 Adult females of the genus Ixodes imbibe blood meals exceeding about 100 times their own weight w

155 promastigotes to persist in the midgut after blood meal excretion was completely lost, and this defec

156 cell membrane integrity, stimulate premature blood meal excretion, and block induced expression of se

157 atrix formed inside the midgut lumen after a blood meal feeding.

158 A blood-meal following mating induced a greater transcript

159 man diseases because they require vertebrate blood meal for egg development.

160 modalities to hunt human hosts and obtain a blood meal for egg production.

161 bolic capacity, spirochetes rely on the tick blood meal for nutrients and metabolic intermediates whi

162 Female mosquitoes require a blood meal for reproduction, and this blood meal provide

163 their obligatory requirement of a vertebrate blood meal for reproduction, these mosquitoes need a lot

164 o Anopheles spp. mosquitoes when they take a blood meal from a host that has recently received one of

165 ature increases dramatically when it takes a blood meal from a warm-blooded, vertebrate host.

166 hen B. burgdorferi-infected ticks take their blood meal from an immunized host.

167 When the tsetse takes a blood meal from an infected human, it ingests bloodstrea

168 etitive PCR, we found that ticks ingesting a blood meal from B-cell-deficient mice, which lack all im

169 e ten-fold more likely to have sourced their blood meal from humans; and a halving in odds of being h

170 Most of ovaries 24 h post second blood meal from iHR3 females in the second cycle were sm

171 cks are responsive to IFNgamma acquired in a blood meal from mice infected with the Lyme disease-caus

172 rvive within Ixodes scapularis ticks after a blood meal from naive mice; however, ticks infected with

173 s is its selection of which host to secure a blood meal from.

174 The ability of C. quinquefasciatus to take blood meals from birds, livestock, and humans contribute

175 Here, we investigated whether blood meals from hematophagous flies could be used to id

176 transmission by killing mosquitoes that take blood meals from IVM-treated humans.

177 Only females are attracted to and obtain a blood-meal from humans, which they use to stimulate egg

178 g sugar feeding, blood feeding and after the blood meal has been processed and excreted, both in the

179 range of environmental sources, most notably blood meal hosts and oviposition sites.

180 as also enhanced when MyD88-/- mice were the blood meal hosts, with the mean pathogen burden at the s

181 ived chemical kairomones in their search for blood meal hosts.

182 biodiversity research, and identification of blood-meal hosts of hematophagous invertebrates.

183 ough many species of mosquitoes never take a blood meal, identifying genes that distinguish blood fee

184 ogens by mosquitoes relies on their taking a blood meal; if there is no bite, there is no disease tra

185 AeHO expression increases after a blood meal in the midgut, and its maximal transcription

186 gametocytes within a newly ingested infected blood meal in the mosquito midgut emerge from erythrocyt

187 ic matrix (PM), which surrounds the infected blood meal in the mosquito midgut.

188 ontaining peritrophic matrix surrounding the blood meal in the mosquito midgut.

189 changes that spirochetes undergo following a blood meal in the tick.

190 effectively disrupts egg development after a blood meal in vivo.

191 ly increases in fat body and ovaries after a blood meal in vivo.

192 o the tsetse fly vector and those exposed to blood meals in the tsetse gut.

193 icited mRNA changes in the spermathecae by a blood-meal in mated females.

194 Additional blood meals increase the sporozoite infection prevalence

195 Similarly, a second blood meal increases the competence of this species for

196 lbachia strain in A. gambiae, and alleviated blood meal-induced mortality in A. stephensi enabling pr

197 phensi, Wolbachia infection elicited massive blood meal-induced mortality, preventing development of

198 achia transmission and partly contributed to blood meal-induced mortality.

199 Blood-meal-induced microperforations in the virus-impene

200 in sub-Saharan Africa, were fed with either blood meal infected with R. felis or infected cellular m

201 Blood meal ingestion leads to midgut tissue distention t

202 MUC1 RNA abundance decreased with time after blood meal ingestion.

203 to activate vitellogenesis in response to a blood-meal-initiated, elevated titer of 20-hydroxyecdyso

204 Blood meal intake resulted in proliferation of pathogeni

205 peritrophic matrix (PM) that forms around a blood meal is a potential barrier of Plasmodium developm

206 lacking OspA is increased when the infecting blood meal is derived from mice that do not produce anti

207 indicating that the oxidative stress after a blood meal is exacerbated by Plasmodium infection.

208 xpression of hsp70, protein digestion of the blood meal is impaired, leading to production of fewer e

209 In hematophagous insects, the blood meal is important for regulating egg maturation.

210 Whether mosquitoes can successfully take a blood meal is not known; however, an arbovirus-infected

211 In anautogenous mosquitoes, a blood meal is required for activation of genes encoding

212 A vertebrate blood meal is required for egg production, and multiple

213 A blood meal is the primary route through which mosquitoes

214 bed, its counterpart during the transmission blood meal is unknown.

215 ls, similar to the increase observed after a blood meal, is critical for 20E stimulation of YPP gene

216 rotein C (OspC), which is induced during the blood meal, is critical for transmission of Lyme disease

217 response, elicited by the temperature of the blood meal, is most robust in the mosquito's midgut.

218 l, additional resources provided by multiple blood meals lead to selection for parasites with slow or

219 Based on 25 blood-meals, mammalian feeding suggests a potential brid

220 t of rapamycin (TOR) pathways in controlling blood-meal-mediated egg maturation in mosquitoes.

221 rbon dioxide enabled females to engorge on a blood meal mimic offered up to 14 min after the initial

222 Eleven days after a Plasmodium-infected blood meal, mosquitoes were treated with M. anisopliae e

223 that reducing the gametocyte density in the blood meal most significantly lowers sporozoite load in

224 During the blood meal, multiple vlsE alleles were observed in the t

225 ication of the species from which a previous blood meal of a hematophagous arthropod was taken is ach

226 the human bloodstream are taken up with the blood meal of the mosquitoes and inactivate parasite dev

227 and further development when taken up in the blood meal of tsetse flies, the vector for trypanosomias

228 technique designed to identify the source of blood meals of haematophagous arthropods.

229 bers, as well as a proportional shift in the blood meals of ticks away from deer.

230 The blood-meal of the tick Rhipicephalus pulchellus lasts fo

231 ly acquired Dps-deficient spirochaetes via a blood meal on mice.

232 e the impact of an additional non-infectious blood meal on parasite development.

233 either by membrane feeding on a virus-spiked blood meal or by feeding on lambs that developed viremia

234 no acids, fatty acids and nucleosides from a blood meal or various host tissues.

235 into mechanisms by which ookinetes exit the blood meal, penetrate and transverse the peritrophic mat

236 ase inhibitor, allosamidin, in an infectious blood meal prevents oocyst development.

237 of allosamidin, a chitinase inhibitor, in a blood meal prevents the parasite from invading the midgu

238 the molecular mechanisms linked to mosquito blood meal processes and reproductive events is of parti

239 e that this boost in temperature following a blood meal prompts the synthesis of heat shock protein 7

240 uire a blood meal for reproduction, and this blood meal provides the underlying mechanism for the spr

241 ngal entomopathogens following an infectious blood meal reduced the number of mosquitoes able to tran

242 ) complex in the apical membrane at 3 h post blood meal, representing a time point after the late pha

243 From a sample of 2,051 identified blood meals, representing 21 mosquito species, mosquitoe

244 ting mosquitoes after oral feeding of spiked-blood meals, representing an additional safety feature.

245 ted salivary glands 14 and 18 days after the blood meal, respectively.

246 h activates ERK in the mosquito gut during a blood meal, restricts viral infection in Drosophila cell

247 by spirochete populations during the nymphal blood meal results from the intricate sequence of transc

248 that acquisition of a second non-infectious blood meal significantly shortens the EIP of ZIKV-infect

249 e addition of MAbs 1A6 and 2B5 to infectious blood meals significantly inhibited oocyst development i

250 owever, no differences in feeding success or blood meal size were found in membrane feeding experimen

251 y, including novel viruses, as well as their blood meal sources.

252 x O (FOXO) and p70 S6 kinase in a tissue and blood meal-specific manner.

253 nced by the axenic state, while in contrast, blood meal status influenced 809 genes.

254 To that end, we have developed a blood meal substitute specifically for mosquitoes infect

255 One example is the lack of a blood meal substitute, which accounts for the Wolbachia-

256 eeding ticks that were infected prior to the blood meal suggests that this surface protein is involve

257 Mosquitoes were fed a blood meal supplemented with [1,2-(13)C2]glucose, and do

258 We next exposed females to blood meals supplemented with allopurinol, a well-charac

259 f Borrelia burgdorferi sensu lato to survive blood meals taken by ticks feeding on birds were analyze

260 th An. arabiensis reducing the proportion of blood meals taken from humans in favour of cattle.

261 n nymph tick survival following the insect's blood meal than before.

262 approximately fivefold more eggs following a blood meal than through autogeny, we suggest that the ma

263 costs, including high mortality following a blood meal, that curtail their propensity for malaria tr

264 oreover, when incorporated into an infective blood meal, the antitrypsin antibodies blocked infectivi

265 hen a mosquito ingests an arbovirus during a blood meal, the arbovirus must escape from the midgut of

266 Before the blood meal, the bacteria in the tick were a homogeneous

267 Within hours after the ingestion of a blood meal, the mosquito midgut epithelium synthesizes a

268 During the blood meal, the population became more heterogeneous; ma

269 After a blood meal, the subcellular localization of TOR shifts f

270 ue to active dispersal by mosquitoes seeking blood meals, there was no statistical basis for choosing

271 During a blood meal, these spirochetes are inoculated into the sk

272 activity of JNJ-A07 when administered in the blood meal to Aedes aegypti mosquitoes.

273 on nectar for metabolic energy but require a blood meal to develop eggs.

274 merous viral diseases, because it requires a blood meal to facilitate egg development.

275 strategy, termed anautogeny, that requires a blood meal to initiate egg maturation.

276 Female mosquitoes need a blood meal to reproduce, and in obtaining this essential

277 The majority of mosquito species require a blood meal to stimulate vitellogenesis and subsequent ov

278 sone is a key regulatory factor, controlling blood-meal triggered egg maturation in mosquitoes.

279 mic immunity, which is activated through the blood meal-triggered cascade rather than by infection.

280 at genes encoding enzymes needed to digest a blood meal (trypsin and a chymotrypsin-like protease) ar

281 e expressed as the female prepares to take a blood meal upon the termination of diapause.

282 itical antibody-shielding role during vector blood meal uptake from immune hosts and is not required

283 s been paid to the mechanism underlining the blood meal uptake into the pharynx through the mouth and

284 smodium developmental stages in the mosquito blood meal using the rodent malaria parasite Plasmodium

285 Comparison of infection via the blood meal versus intrathoracic injection, which bypasse

286 lase captures plasminogen from the mammalian blood meal via its lysine motif (DKSLVK) and that this i

287 ing the source of the remnants of a previous blood meal via shotgun proteomics and spectral matching.

288 Although fecundity after a single blood meal was unaffected by long or short residence and

289 hly expressed in midguts and up-regulated by blood meals were chosen for analysis.

290 Midguts, dissected 48 hr after an infected blood meal, were used to prepare two RNA bulks, each rep

291 a narrow window time at the beginning of the blood meal when antibodies bind to OspA-expressing spiro

292 y in the midgut within the first 48 h of the blood meal, when ticks acquire infection.

293 Among them are blood products and blood meal, which are used as high-quality material for

294 d by an insect vector during the taking of a blood meal, which directly links nutrient acquisition an

295 ars to have perished immediately following a blood meal, which may have been from coexisting mammals,

296 Consumption of a blood meal, which primarily consists of protein by dry w

297 s contributes to arboviral infection after a blood meal, which suppresses antiviral innate immunity b

298 ambiae gut leading to the utilization of the blood meal will result in a deeper understanding of the

299 vo phospholipids by supplementing infectious blood meals with a de novo phospholipid precursor.

300 nsmission by Ae. aegypti after an infectious blood meal, with 5% saliva-positive mosquitoes for ZIKVD