ライフサイエンスコーパス: blood spot

1 r and the time since deposition (TSD) of the blood spot.

2 the age of the originator and the TSD of the blood spot.

3 ta9-tetrahydrocannabinol (THC) from a single blood spot.

4 s occasionally observed with FFPET and dried blood spot.

5 h higher LINE1 methylation levels in newborn blood spots.

6 more sensitive for CMV detection than dried blood spots.

7 roscope) and another one consisting of dried blood spots.

8 currently used PCR methods from filter paper blood spots.

9 immune function, measured in neonatal dried blood spots.

10 c DNA obtained from Guthrie cards with dried blood spots.

11 riptyline, lidocaine, and sunitinib in dried blood spots.

12 s of HIV infection in infants by using dried blood spots.

13 trophy by the creatine kinase level on dried blood spots.

14 od to detect HIV type 1 (HIV-1) DNA in dried blood spots.

15 rom children with available neonatal Guthrie blood spots.

16 entrations of tenofovir diphosphate in dried blood spots.

17 hors measured EDA in serum, saliva and dried blood spots.

18 enofovir diphosphate concentrations in dried blood spots.

19 correlated with CMV viral load in the dried blood spots.

20 sed to spot the blood, or the temperature of blood spotted.

21 ive metabolite, in cervical tissue and dried blood spots 1 month after each ring insertion.

22 rson-years if drug was not detected in dried blood spots, 2.3 infections per 100 person-years if drug

23 L (3.47 pmol/L), total testosterone in dried blood spots (8-10 muL) with a LLOQ of 40 pg/mL, and free

24 ning materials originally designed for dried blood spot analysis with stable isotope dilution analysi

25 l in Kampala, Uganda, and obtained for dried blood spot analysis.

26 ction of expanded CGG alleles using a single blood spot and in principle is suitable for large scale

27 nevirapine exposure was developed from dried blood spot and plasma nevirapine concentrations at study

28 e at room temperature, the punched out dried blood spot and the foam was dissolved in 300 muL of 1 mM

29 We obtained archived residual dried blood spots and data for nearly all IEM cases from the 4

30 y (ELISA) for quantifying insulin from dried blood spots and demonstrate its application in a large t

31 ex assay of 10 enzymatic activities in dried blood spots and fibroblast lysates that allow newborn sc

32 elf to samples such as tumor biopsies, dried blood spots and fluids including urine and CSF to develo

33 twin pairs using DNA isolated from neonatal blood spots and identified genes affected by extremely r

34 ples enriched for proviral DNA such as dried blood spots and increased use of next-generation sequenc

35 ith activity data determined from both dried blood spots and serum samples, giving an informative dia

36 TFV-DP in dried blood spots and sex hormones in serum were measured at w

37 cent improvements for accurately using dried blood spots and the imminent appearance to the market of

38 inflammatory marker levels in neonatal dried blood spots and their association with later risk of sch

39 LISA) for quantifying adiponectin from dried blood spots and then demonstrate its application in a la

40 es from biological substrates, such as dried blood spots and thin tissue sections, by use of native-l

41 onication) of the paper containing the dried blood spots, and acidification of extraction solvents.

42 red levels of tenofovir diphosphate in dried blood spots; and (3) examine patterns of risk behavior w

43 Cotinine levels in dried blood spots are an accurate biomarker of maternal smokin

44 The archived dried blood spots are an important and precious resource for g

45 Drug concentrations in dried blood spots are strongly correlated with protective bene

46 lical cord blood to assess cotinine in dried blood spots as a biomarker of maternal smoking close to

47 th: (i) C-reactive protein, assayed in whole-blood spots as an indicator of immunostimulation; (ii) s

48 y their performance in reactions using dried blood spots as the enzyme source.

49 Bio-sampling was randomised to blood spot, buccal cell or no request.

50 istance genes in respiratory fluid and dried blood spots, but FLASH-NGS is applicable to all areas th

51 protein) were analyzed in eluates from dried blood spots by enzyme-linked immunosorbent assay.

52 variants by direct surface sampling of dried blood spots by use of an Advion Triversa Nanomate automa

53 Dried blood spots can be used for comprehensive, untargeted li

54 tion-mass spectrometry in conjunction with a blood spot cartridge that we can determine the relative

55 in 61% (125/201) of randomly selected dried blood spots collected at the first follow-up visit.

56 cts from human whole blood samples and dried blood spots collected on chromatography paper.

57 d validation of a at-home finger-prick dried blood spot collection kit and an analysis method.

58 -HRMS) in archived DBS samples (in total, 51 blood spot composites from 1224 newborns) collected from

59 Blood volume in dried blood spot (DBS) analysis is assumed to be constant for

60 A fixed area punch in dried blood spot (DBS) analysis is assumed to contain a fixed

61 The use of dried blood spot (DBS) and dried urine spot (DUS) samples repr

62 omparison of Aptima results for paired dried blood spot (DBS) and plasma specimens archived from part

63 As a part of data collection, dried blood spot (DBS) and urine samples are being collected t

64 his study were to develop and validate dried blood spot (DBS) assays for the quantification of ambris

65 Since March 2004, we obtained 2135 dried blood spot (DBS) citrulline samples from 57 intestinal t

66 ly sequence 100 targets and applied to dried blood spot (DBS) controls and field isolates from Mozamb

67 A dried blood spot (DBS) is a well-accepted means for the collec

68 -concept study combining water-soluble dried blood spot (DBS) material in liquid chromatography-tande

69 The dried blood spot (DBS) matrix has significant utility for appl

70 Monitoring by dried blood spot (DBS) provides patients the opportunity to sa

71 ith the bioanalytical methods used for dried blood spot (DBS) sample analysis.

72 ty issues associated with conventional dried blood spot (DBS) sample when a subpunch is taken.

73 )D3] concentrations in stored neonatal dried blood spot (DBS) samples are associated with pediatric f

74 To improve EID services in Ukraine, dried blood spot (DBS) samples obtained from 237 HIV-exposed c

75 Dried blood spot (DBS) samples on filter paper are surging in

76 sing paired reconstituted dried filter paper blood spot (DBS) samples to assess the feasibility of us

77 of detection (LLOD) for Aptima HCV on dried blood spot (DBS) samples was calculated to be 2.43 log(1

78 ts and modified species extracted from dried blood spot (DBS) samples with virtually no sample prepar

79 olution Melting (MS-HRM) approach from dried blood spot (DBS) samples, assessing the different DNA is

80 quantitative bioanalysis of drugs from dried blood spot (DBS) samples, using an MS detector, with or

81 lin can be measured in either serum or dried blood spot (DBS) samples.

82 ul for online cleanup of extracts from dried blood spot (DBS) samples.

83 in physiological solutions, urine, and dried blood spot (DBS) samples.

84 s an increasing interest in the use of dried blood spot (DBS) sampling and multiple reaction monitori

85 The potential of dried blood spot (DBS) sampling as an alternative for classica

86 Dried blood spot (DBS) sampling is a promising method for coll

87 Dried blood spot (DBS) sampling is recognized as a valuable al

88 We instituted dried blood spot (DBS) specimen monitoring of citrulline to si

89 Blood samples were collected as dried blood spot (DBS) specimens from all participants for qua

90 Dried blood spot (DBS) specimens were tested for neutralizing

91 gained substantial experience with the dried blood spot (DBS) technique as an alternative.

92 The dried blood spot (DBS) technique can be used to collect, store

93 , and simplified shipping and storage, dried blood spot (DBS) techniques have faced adoption resistan

94 Dried blood spot (DBS) technology is believed to be a viable s

95 reement between CRP values obtained by dried blood spot (DBS) versus conventional venepuncture sampli

96 Dried blood spot (DBS), dried plasma spot (DPS), and plasma sp

97 umbilical cord (UC) tissue and newborn dried blood spot (DBS)-extracted genomic DNA (gDNA) as an alte

98 of Nf-L in blood fractions obtained from dry blood spots (DBS) and dry plasma spots (DPS), two filter

99 and black carbon (BC), and collecting dried blood spots (DBS) and urinary samples for biomarker anal

100 Dried blood spots (DBS) are an alternative specimen type for H

101 Dried blood spots (DBS) are often used as a less invasive alte

102 Since dried blood spots (DBS) are routinely collected for metabolic

103 Dried blood spots (DBS) are simpler to prepare, store, and tra

104 Drug concentrations in hair and dried blood spots (DBS) are used to assess long-term-exposure;

105 Dried blood spots (DBS) are useful for molecular assays but ar

106 nder the development and acceptance of dried blood spots (DBS) as a widely used quantitative bioanaly

107 ral therapy (ART) guidelines recommend dried blood spots (DBS) as an alternative specimen type for vi

108 S assay to determine subtype B DRMs in dried blood spots (DBS) collected from patients on antiretrovi

109 Dried blood spots (DBS) collected onto filter paper have eased

110 The use of dried blood spots (DBS) could ameliorate many problems of vita

111 s (CMV) load in finger-stick-collected dried blood spots (DBS) could potentially be useful for field

112 cytes isolated by magnetic sorting and dried blood spots (DBS) derived from 50 mul of peripheral bloo

113 bust LC-MS/MS-based enzyme assay using dried blood spots (DBS) for the diagnosis of pyridox(am)ine 5'

114 for online extraction and analysis of dried blood spots (DBS) from DBS paper cards to a multidimensi

115 We tested 617 dried blood spots (DBS) from human immunodeficiency virus-expo

116 Dried blood spots (DBS) have been used as alternative specimen

117 HIV Early Infant Diagnosis (EID) from dried blood spots (DBS) in low- to middle-income countries sin

118 ough tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is a predictor of adherence and pre-ex

119 Tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is associated with viral suppression i

120 ate (TFV-DP) concentration measured in dried blood spots (DBS) is used to monitor cumulative adherenc

121 ethod for analyzing perchlorate in the dried blood spots (DBS) of newborns.

122 ncentrations in clinical studies using dried blood spots (DBS) on paper, rather than conventional pla

123 PoC-EID testing, using fresh blood and dried blood spots (DBS) samples at obstetric health facilities

124 examined the stability of HIV-1 DNA in dried blood spots (DBS) stored in humid heat and at -20 degree

125 cury (THg) and methylmercury (MeHg) in dried blood spots (DBS) though more research is required to ev

126 se A (ARSA) activity in leukocytes and dried blood spots (DBS) using deuterated natural sulfatide sub

127 on (LOD) of the new test in plasma and dried blood spots (DBS) was determined with the 2nd Internatio

128 In total, dried blood spots (DBS) were collected from 276 individuals.

129 HIV genotyping from dried blood spots (DBS) with noncommercial (in-house) assays m

130 inborn errors of metabolism (IEM) from dried blood spots (DBS) with quality assurance.

131 um samples and 40-10,000 pg/mL for the dried blood spots (DBS) with R(2) >0.998.

132 stick placed on filter paper (known as dried blood spots (DBS)) is more advantageous.

133 re IFX in 100-fold diluted extracts of dried blood spots (DBS), and LOD achieved was below 2 ng/mL.

134 pic acid (alpha-AAA) in plasma, serum, dried blood spots (DBS), urine and dried urine spots (DUS).

135 for early infant diagnosis of HIV from dried blood spots (DBS), viral load monitoring with this syste

136 Dried blood spots (DBS)-based drug resistance testing, widely

137 ould facilitate more widespread use of dried blood spots (DBS).

138 tion of methotrexate polyglutamates in dried blood spots (DBS).

139 e the analysis of therapeutic drugs in dried blood spots (DBS).

140 d yield of DNA extracted from neonatal dried blood spots (DBS).

141 0), cerebrospinal fluid (CSF; n = 36), dried blood spots (DBS; n = 104), and dried plasma spots (DPS;

142 eloped and applied a broadly sensitive dried-blood-spot (DBS)-based genotyping assay for surveillance

143 s of targeted drugs and metabolites in dried blood spots (DBSs) and whole mouse thin tissue sections

144 fornia, 3,252,156 infants had DNA from dried blood spots (DBSs) assayed for T-cell receptor excision

145 s spectrometry (tandem-MS) analysis of dried blood spots (DBSs) collected at birth can identify newbo

146 Dried blood spots (DBSs) could circumvent many logistical chal

147 In 1 of 4 provinces, we also collected dried blood spots (DBSs) for plasma HIV RNA testing.

148 n identify metabolite abnormalities in dried blood spots (DBSs) from affected patients, with the fina

149 ervational cohort study using data and dried blood spots (DBSs) from the Breastfeeding, Antiretrovira

150 The importance of dried blood spots (DBSs) has increased in medical care.

151 Dried blood spots (DBSs) have gained increasing attention rece

152 Dried blood spots (DBSs) have had a long history in disease sc

153 e in resource-limited settings, use of dried blood spots (DBSs) is being adopted.

154 Ten dried blood spots (DBSs) were assembled that contained P. falc

155 Dried blood spots (DBSs) were collected to estimate seroprotec

156 Dried blood spots (DBSs), collected for the newborn screening

157 Blood spot DNA from this subject displayed chimerism in

158 Whole genome amplification of dried blood spot DNA has been used to provide DNA for genome-w

159 A set of 384 SNPs were genotyped in blood spot DNA samples from 447 P. falciparum infected s

160 tion method to amplify parasite genomes from blood spot DNA samples.

161 more robust than genotyping amplified dried blood spot DNA, is comparable in cost, and can be done w

162 re robust, high-accuracy genotyping of dried blood spot DNA.

163 f the coating was then used for an extracted blood spot (EBS) sampling approach, a new sampling metho

164 erythronate in stable isotope-assisted dried blood spot experiments.

165 quires a simple extraction step from a dried blood spot followed by the quantification of product by

166 is used genomic DNA extracted from the dried blood spot followed by whole genome amplification with a

167 ning by creatine kinase (CK) levels in dried blood spots followed by mutation detection in those with

168 However, homogenization of the dried blood spots, followed by a 24 h exposure to solvents, an

169 ces provided anonymous survey data and dried blood spots for HIV serostatus assessment.

170 ences, and 1,220 (70.2%) also provided dried blood spots for HIV testing.

171 ) based assays of lysosomal enzymes in dried blood spots for the early detection of Pompe, Fabry, and

172 sed elevated creatine kinase levels in dried blood spots for the initial screening, with the diagnosi

173 for the Determine and Vikia tests and dried blood spots for the reference standard test (AxSYM HBsAg

174 tested for malarial parasitemia using dried blood spots from 12, 24, and 36 weeks of age.

175 Paediatricians collected a median of 8 blood spots from 13,487 (97%) children.

176 plication) in which paediatricians collected blood spots from 13,879 children aged 11.5 years from 31

177 ative household survey which collected dried blood spots from 15,125 asymptomatic individuals ages 15

178 , prediagnosis samples in 4 of 16), neonatal blood spots from 21 DS children without clinically evide

179 We examined neonatal blood spots from 214 children with ASD (141 severe, 73 m

180 tic Disease Screening Program provided dried blood spots from 428 newborns delivered in 2001-2003 wit

181 hen compared with microscopy using 891 dried blood spots from a cohort of 77 Ugandan children followe

182 were measured in eluates from neonatal dried blood spots from cases, controls, and siblings using a b

183 We analyzed 911 dried blood spots from Ghana (n = 165), Tanzania (n = 176), an

184 1) and tripeptidyl peptidase (TPP1) in dried blood spots from newborns using tandem mass spectrometry

185 We collected blood spots from patients with microscopy or rapid test

186 ally identified TEL-AML1 fusion sequences in blood spots from the identical twins, diagnosed with con

187 exity are high, DNA was extracted from dried blood spots, genes of interest were amplified, amplicons

188 found that measurements of cotinine in dried blood spots had high sensitivity (92.3%) and specificity

189 The use of dried blood spots has increased in research and clinical setti

190 e acyl-specific lipidomic profiling of dried blood spots has yet to be examined.

191 and transportation of samples, such as dried blood spots, has improved test accessibility, the result

192 Studies in monozygotic twins and archived blood spots have provided compelling evidence of a singl

193 sm, this patient had a persistently elevated blood spot hydroxybutyrylcarnitine concentration when fe

194 sequencing of FFPET, whole blood, and dried blood spot in the evaluation of inherited CV disorders.

195 ly quantified fasting adiponectin from dried blood spots in 13,329 of 13,879 (96%) children.

196 Paediatricians collected dried blood spots in a follow-up of 13,879 fasted children age

197 ne kinase (CK) levels are increased on dried blood spots in newborns related to the birthing process.

198 ucocerebrosidase enzymatic activity in dried blood spots in patients with Parkinson's disease (n = 51

199 ured drug concentrations in plasma and dried blood spots in seroconverters and a random sample of ser

200 19%-47%) by increasing DNA input from dried blood spots into polymerase chain reaction.

201 n real time (DART)-MS/MS, where, for a 5 muL blood spot, LOQs of 0.2 and 1 mug/mL, respectively, were

202 ood specimens from newborns, stored as dried blood spots, may provide a low-cost method to objectivel

203 us levels were assessed by a validated dried blood spot method for sampling and measurement.

204 d by the patients themselves using the dried blood spot method.

205 men type (FFPET versus whole blood and dried blood spot; n=12).

206 Measured dried blood spot nevirapine concentrations were higher than th

207 l receptor excision circles (TRECs) in dried blood spots obtained at birth permits population-based n

208 The authors analyzed archival dried blood spots obtained from newborns to assess whether lev

209 mately 3 microL of blood) punched from dried blood spots obtained from: i) whole blood standards (val

210 1 methylation in DNA isolated from the dried blood spots of 36,124 deidentified newborn males.

211 rs of T and B cell numbers in neonatal dried blood spots of 99 children with cCMV and 54 children wit

212 c gene fusion sequences in archived neonatal blood spots of individuals who subsequently developed le

213 kemia and retrospective scrutiny of neonatal blood spots of patients with leukemia indicate that chro

214 ave been developed for the analysis in dried blood spots of steroids and lysosomal enzymes.

215 r detection of malaria parasites using dried blood spots offers a sensitive and efficient approach fo

216 Sample preparation of blood spots on commercial cards was also performed (What

217 blood films for microscopic examination and blood spots on filter paper.

218 ative analysis of enzyme activities in dried blood spots on newborn screening cards has emerged as a

219 in Western Kenya, in the form of both dried blood spots on Whatman filter paper, and the blood spot

220 We used dried blood spots once every 6 months provided by participants

221 lonotypic E2A-PBX1 translocation in neonatal blood spots, or Guthrie cards, obtained from the childre

222 hod allows for repeated analysis of a single blood spot over a prolonged time period and is tolerant

223 tients and 619 endemic controls and on dried blood spots prepared with plasma of 95 gHAT and 37 endem

224 ion of enzyme-specific substrates with dried blood spot punches or fibroblast lysate followed by quan

225 ne, phenylalanine, and methionine on a dried blood spot requiring a 2 min run.

226 We obtained punch samples from dried blood spots routinely collected from HIV-exposed infants

227 aviours, and service use and to give a dried blood spot sample that was tested anonymously for the pr

228 At the final study visit, a dried blood spot sample was obtained for viral load and genoty

229 infection status, as determined by the dried blood spot sample.

230 t efficacy with other sample matrices, dried blood spot samples (n = 63) were obtained and evaluated

231 he first to sequence BPD exomes from newborn blood spot samples and identify with high confidence gen

232 l load in many countries is to collect dried blood spot samples for testing in regional laboratories;

233 Dried blood spot samples from mothers and their offspring atte

234 Using dried blood spot samples from patients with suspected malaria

235 DNA was extracted from the neonatal dried blood spot samples obtained from the Danish Neonatal Scr

236 targeted profiles can be obtained from dried blood spot samples that are comparable with whole blood

237 Dried blood spot samples were collected from HIV-exposed child

238 April 5, 2007, and Oct 1, 2014, 16 046 dried blood spot samples were sent from 8859 children in 364 h

239 iquid extraction surface analysis from dried blood spot samples, where hemoglobin is highly abundant.

240 m DNA methylation of neonatal cord blood and blood spot samples.

241 been reported for tissue sections and dried blood spot samples.

242 ns using 30,547 deidentified anonymous dried blood spot samples.

243 inst COVID-19 in human blood serum and dried blood spot samples.

244 troduced to address the limitations of dried blood spot sampling.

245 indicates that current approaches to newborn blood spot screening (NBS) education are ineffective.

246 first recognised, the performance of newborn blood spot screening (NBS) has been continually assessed

247 With dried blood spots, sensitivity was 92.6% (95% CI 85.4 - 97.0),

248 will facilitate the quality control of dried blood spot sequencing.

249 ty of our method for drug screening on dried blood spots showing excellent linearity (R(2) of 0.998)

250 is of IdS-S by IdS found within a 3 mm dried blood spot specifically produces a nonsulfated product (

251 tes the correlation between plasma and dried blood spot specimen citrulline concentrations after inte

252 Serum and dried blood spot specimens collected for yaws surveillance pro

253 col to assess resistance using remnant dried blood spot specimens from a representative sample of chi

254 FPET (heart) and blood (whole blood or dried blood spot) specimens underwent targeted next-generation

255 r a prolonged time period and is tolerant of blood spot storage conditions.

256 Diet and dried blood spot TC and omega-3 (n-3) index were determined at

257 ood specimens were collected using the dried blood spot technique from 9629 residents (87.6%), and sa

258 6-59 months in each neighborhood, the dried blood spot technique was used to evaluate immunoglobulin

259 le volume restrictions associated with dried-blood-spot technology.

260 Median age at first dried blood spot test was 2.1 (IQR 1.8-2.5) months.

261 67%) individuals with a first negative dried blood spot test, 14 223 (80%) had subsequent dried blood

262 adherence, assessed by drug levels in dried blood spots tested monthly for the first 3 months.

263 Early infant diagnosis with dried blood spot testing had high uptake in primary care setti

264 Early infant diagnosis with dried blood spot testing was provided by the National AIDS Pro

265 deficiency-which can be diagnosed using dry blood spot testing-is often misdiagnosed as non-alcoholi

266 ion antibody and antigen technologies, dried-blood-spot testing, and self-testing.

267 8 DNA methylation levels measured in newborn blood spot tests, and carotid intima-media thickness (CI

268 spot test, 14 223 (80%) had subsequent dried blood spot tests, of whom 503 seroconverted after follow

269 omole quantities of enzymatic products per a blood spot that are quantified by tandem mass spectromet

270 blood spots on Whatman filter paper, and the blood spot that is dropped into rapid diagnostic tests d

271 ure to extract DNA from a portion of a dried blood spot that provides sufficient unamplified genomic

272 d-smear microscopy and PCR analysis of dried blood spots that had been collected every 2 weeks for 7

273 Dried blood spots that had been stored ambiently for 3 to 6 ye

274 Blood spots that were classified as negative were uninfo

275 and in DBS samples; effect of the volume of blood spotted, the device used to spot the blood, or the

276 the input sample volume is much smaller in a blood spot, there is a risk of false negatives with DBS.

277 we introduce a 2-tier system using the dried blood spot to first assess CK with follow-up DMD gene te

278 and uses predetermined levels of CK on dried blood spots to predict DMD gene mutations.

279 The use of dried blood spots to stabilise and ship samples from clinics t

280 is article compares cotinine levels in dried blood spots to those in umbilical cord blood to assess c

281 markers were measured in eluates from dried blood spots using a bead-based multiplex assay.

282 RNA viral load measurements taken from dried blood spots using a reference panel and field-collected

283 A dried blood spot was collected from each child and tested for

284 R assay with DNA isolated from routine dried blood spots was developed.

285 ucocerebrosidase enzymatic activity in dried blood spots was measured by a mass spectrometry-based as

286 Cotinine in dried blood spots was measured in 6.35--mm punches by using li

287 ebruary, 2014, and March, 2015, 99,243 dried blood spots were analysed and results were available for

288 For genetic testing, dried blood spots were collected and nine variants in four gen

289 Blood spots were collected at each observation and assay

290 Dried blood spots were collected from a pilot subset of infant

291 Cord and heel prick blood spots were collected in Bangladesh and analyzed at

292 dial infection using GeneXpert platform, and blood spots were collected on filter paper and dried to

293 bs were tested for chlamydial infection, and blood spots were collected on filter paper to test for a

294 globin density was measured and filter paper blood spots were collected to determine age-specific ser

295 Dried blood spots were extracted using a methanolic solution o

296 Repeated measures of cotinine in dried blood spots were highly correlated (R(2) = 0.99, P < 0.0

297 ssion revealed that cotinine levels in dried blood spots were slightly lower than those in umbilical

298 enofovir diphosphate concentrations in dried blood spots were stable and high.

299 nk was used to chromatographically elute the blood spot with 0.9% NaCl buffer for 10 min by capillary

300 ted (R(2) = 0.99, P < 0.001) among 100 dried blood spots with cotinine quantitated in 2 separate punc