ライフサイエンスコーパス: blood vessel

1 responses (e.g. when platelets interact with blood vessels).

2 ation do not necessarily occur together in a blood vessel.

3 le-cell atlas of gene expression in a normal blood vessel.

4 m thrombus and thus the sealing of a damaged blood vessel.

5 areas, tumor stroma, and tumor-infiltrating blood vessels.

6 ork for measuring flow rates from individual blood vessels.

7 ing positions of epipapillary and epiretinal blood vessels.

8 ctivity reporter and an anatomical marker of blood vessels.

9 well as the frequency of Tie2-positive tumor blood vessels.

10 in angiogenesis, the process of forming new blood vessels.

11 is required for anastomosis of DPSC-derived blood vessels.

12 s can be regenerated from small fragments of blood vessels.

13 and are supported by an aberrant network of blood vessels.

14 gical processes and diseases involving human blood vessels.

15 the forces applied to various segments along blood vessels.

16 ombinations of trafficking signals in nearby blood vessels.

17 helial and smooth muscle cells cultured from blood vessels.

18 of PDGF receptor beta-positive pericytes to blood vessels.

19 age to the host if they over-activate within blood vessels.

20 ancing the barrier properties of spinal cord blood vessels.

21 suppressing the formation of larger-diameter blood vessels.

22 keletal reorganization, and formation of new blood vessels.

23 lial cells, the cells lining the interior of blood vessels.

24 ells, usually located surrounding airways or blood vessels.

25 ey drivers of diabetic vasculopathy in human blood vessels.

26 tablished corneal lymphatic vessels, but not blood vessels.

27 tosis, leading to massive pruning of nascent blood vessels.

28 on solid tumor interactions with functional blood vessels.

29 which types of lymphocytes reside closest to blood vessels; (3) Identify multiple subsets of T and B

30 eurons, astrocytes and cell processes around blood vessels(8,9).

31 crease their energy supply by dilating local blood vessels, a mechanism termed neurovascular coupling

32 metabolism, has a strong impact on cerebral blood vessels, a phenomenon known as cerebrovascular rea

33 l studies suggest that Abeta and tau lead to blood vessel abnormalities and blood-brain barrier (BBB)

34 The formation of new blood vessels after myocardial infarction (MI) is essent

35 and fluid homeostasis of maintaining healthy blood vessels, an increasingly pertinent issue in an agi

36 lection of cellular phenotypes, branching of blood vessels, anastomosis (fusion of blood vessels) and

37 of this study was to examine the efficacy of blood vessel and bone formation following transfection w

38 ell (HUVEC)-lined, perfusable, bioengineered blood vessel and tumor spheroids embedded in an extracel

39 scular endothelium forms the inner lining of blood vessels and actively regulates vascular permeabili

40 cells, which infiltrate the spleen and major blood vessels and are accompanied by aberrant systemic i

41 pitulate the structure and function of human blood vessels and are amenable systems for modelling and

42 d could be identified in close apposition to blood vessels and at sites distant from them.

43 loped here permits targeted gene delivery to blood vessels and could be used to promote angiogenesis,

44 that can selectively disrupt immature tumor blood vessels and exacerbate the tumor hypoxia state.

45 leton, a majority of which adjoin sinusoidal blood vessels and express C-X-C motif chemokine ligand 1

46 sted after removing contributions from large blood vessels and gravitational gradients (all P < 0.05)

47 sted after removing contributions from large blood vessels and gravitational gradients.

48 ssion of alpha-smooth muscle actin in dermal blood vessels and improve the impaired neovascularizatio

49 shion on astroglia, surrounding all types of blood vessels and in continuous string-like structures a

50 important in maintaining retinal neurons and blood vessels and is a factor contributing to the risk f

51 genic factors, resulting in the retention of blood vessels and macrophages.

52 l to the stability and function of capillary blood vessels and microvessels.

53 y betaA-Akt1WT/flx embryos had fewer visible blood vessels and more hemorrhages than their wild-type

54 Blood vessels and nerves travel together to supply most

55 lectively affected cardiomyocytes but spared blood vessels and nervous tissue.

56 The proper interactions between blood vessels and neurons are critical for maintaining t

57 ural cells in the brain parenchyma including blood vessels and neurons, and in particular NPY and POM

58 e of [(18)F]fluoro-PEG-folate from heart and blood vessels and no dose limiting uptake in organs.

59 Lung blood vessels and NOS3 expression decreased and the exte

60 phase resolution is delayed, with persistent blood vessels and reduced dermal collagen at 10 days.

61 Mast cells (MCs), which line blood vessels and regulate vascular function, are able t

62 ophages, they uniquely interact closely with blood vessels and release an extensive set of mediators

63 positive cells) because they reside close to blood vessels and require a small diffusion distance to

64 D7c is required for the normal growth of CNS blood vessels and that ablation of this gene results in

65 ation of cell atlases of mammalian heart and blood vessels and the elucidation of mechanisms involved

66 of LT-HSCs resides close to both sinusoidal blood vessels and the endosteal surface.

67 Molecular crosstalk between intra-tumor blood vessels and tumor cells plays many critical roles

68 ing of blood vessels, anastomosis (fusion of blood vessels) and angiogenesis velocity.

69 for the identification of the primary tumor, blood vessel, and lymphatic metastasis.

70 ll types, including neurons, glial cells and blood vessels, and are involved or implicated in brain d

71 mRNA and protein, a nonspecific claudin for blood vessels, and downregulation in claudin-5 expressio

72 eatures include immune cells, stromal cells, blood vessels, and extracellular matrix.

73 coupling, reduces amyloid deposition around blood vessels, and improves cognition in a mouse model o

74 To form new blood vessels (angiogenesis), endothelial cells (ECs) mu

75 In solid tumors, blood vessels are abnormal and dysfunctional and, thus,

76 Tumor blood vessels are chaotic and abundantly distributed, ow

77 Blood vessels are comprised of endothelial and smooth mu

78 Blood vessels are covered with endothelial cells on thei

79 Blood vessels are lined by endothelial cells engaged in

80 gical neovascular tufts while sparing normal blood vessels are needed.

81 s in the lower extremities of the body where blood vessels are often poorly oxygenated.

82 elanoma we show that when 50% or more tumour blood vessels are pericyte-FAK negative, melanoma patien

83 nulus area after subtraction of noncapillary blood vessel areas.

84 acement in z was calculated using dye-filled blood vessels as an anatomical marker, providing high co

85 s results in significant disruption of these blood vessels as observed in pathological conditions, in

86 ovarian tissue has larger and more tortuous blood vessels as well as smaller vessels of different si

87 and exhibit vascular anomalies within major blood vessels as well.

88 on within the meniscus appeared to have less blood vessels associated with them in the vascular regio

89 njection of the PGCs into the extraembryonic blood vessel at the early embryonic stages when endogeno

90 neutrophils to favor homeostatic egress from blood vessels at night, resulting in boosted anti-microb

91 e achieved reliably, although shadowing from blood vessels at the neuroretinal rim remains an issue.

92 eat promise for medical diagnosis related to blood vessels because it possesses deep penetration and

93 er in the structure and function of cerebral blood vessels, but how these cerebrovascular effects lea

94 Enhanced blood vessel (BV) formation is thought to drive tumor gr

95 Blood vessels (BV) in LN are highly specialized, featuri

96 Blood vessels (BVs) are considered an integral component

97 AuNPs, which enables detection of individual blood vessels by both imaging modalities.

98 ly, disrupting the orientation of angiogenic blood vessels by misdirecting them results in contorted

99 n in ECs leading to AVM formation, increased blood vessel calibers, and changes in EC morphology in t

100 e function of annular spaces around cerebral blood vessels, called perivascular spaces (PVS), through

101 t also nondiseased organs (e.g., kidney) and blood vessels can express high levels of certain GSLs, n

102 orpus callosum of a monkey brain reveal that blood vessels, cells, and vacuoles affect axonal diamete

103 and lacked the cylindrical morphology around blood vessels characteristic of sympathetic innervation.

104 uggesting dense tanycyte/neuron and tanycyte/blood vessel communications.

105 Blood vessels composed of endothelial cells (ECs) contac

106 Central nervous system (CNS) blood vessels contain a functional blood-brain barrier (

107 inherently disorganised collection of leaky blood vessels contribute significantly to suboptimal tre

108 ors from mice treated with 5E1 had decreased blood vessel density and increased DNA damage suggestive

109 o those with increased tumour size, enhanced blood vessel density and metastasis.

110 Decreased EGR1 expression led to reduced blood vessel density in brain and bone metastases as wel

111 gene encoding prion protein 2 (Prnd) in CNS blood vessel development and physiology.

112 ment analysis found that DEGs contributed to blood vessel development, extracellular structure organi

113 ed that MAP is inversely related to cerebral blood vessel diameters (p-value < 0.05) globally (over t

114 t and quantify cerebrovascular changes (i.e. blood vessel diameters and tortuosity changes) using mag

115 en mean arterial pressure (MAP) and cerebral blood vessels' diameters and tortuosity alterations.

116 r system to quantify alterations in cerebral blood vessels' diameters; 3) Calculation of mean and Gau

117 Tumor-associated blood vessels differ from normal vessels and play key ro

118 eased by exposure to dynamic visual stimuli, blood vessels dilate and the flow of blood within vessel

119 rintensity - morphological findings of small blood vessel disease of the brain.

120 adipose tissue (eWAT) tightly associate with blood vessels, displaying very high endocytic capacity.

121 at in lung tissue the fluid derived from the blood vessels drains through the interstitium into the l

122 400-nm photoexcitation light in superficial blood vessels during circulation, and turned on by FUS t

123 Upregulated MMP14 levels correlated with blood vessel dysfunction and a lack of cytotoxic T cells

124 pheral T cells, including T-cell adhesion to blood vessel endothelium, endothelial activation, and T-

125 , characterized by EC hyperproliferation and blood vessel enlargement.

126 Blood vessels exhibit regional defects in endothelial co

127 Human blood vessels, exposed in vivo to a diabetic milieu in m

128 ther point of care testing or insertion into blood vessels for continuous sepsis monitoring.

129 s to intentionally block diseased or injured blood vessels for therapeutic purposes.

130 ogenic and support recipient-derived de novo blood vessel formation across the entire graft thickness

131 new insights into fundamental principles of blood vessel formation and Apelin signaling, enabling a

132 al role for RhoJ in matrix remodeling during blood vessel formation and demonstrate a functional inte

133 dhesion kinase differentially regulate tumor blood vessel formation and remodeling.

134 n, suggesting that HE4 may cause deregulated blood vessel formation and suppress proper T cell traffi

135 overage, suggesting that pericytes influence blood vessel formation in an Olfml3-dependent manner.

136 these vasculogenic foci were a source of new blood vessel formation in the developing brain.

137 cell death signaling molecules contribute to blood vessel formation is still not well understood.

138 Blood vessel formation requires endothelial cell (EC) mi

139 ulate CNS endothelial cell proliferation and blood vessel formation through hypoxia inducible factor

140 his axis could play an important role during blood vessel formation, tissue perfusion, and oxygen res

141 s accompanied by an extensive network of new blood vessel formation.

142 ardiac hypertrophy, Hirschsprung disease and blood vessel formation.

143 ty to promote fibrin degradation and inhibit blood vessel formation.

144 sis, invasion, and of factors that stimulate blood vessels formation.

145 onstruction of the lesion and its associated blood vessels from a uCT scan.

146 ry arterial ECs from diabetic donors, and on blood vessels from diabetic critical limb ischemia patie

147 Angiogenesis, the formation of new blood vessels from pre-existing ones, occurs in pathophy

148 Angiogenesis involves the formation of new blood vessels from preexisting ones, and it is an essent

149 me difference (AVVD) in delineating cerebral blood vessels from surrounding tissues compared to the g

150 ysiological process for the formation of new blood vessels from the pre-existing vessels and it has a

151 mediated regulation of claudin-5 was lost in blood vessels from tissue biopsies from patients with gl

152 the anastomosis of the host vasculature with blood vessels generated by DPSCs (a model for mesenchyma

153 clude increased ventilation, cardiac output, blood vessel growth and circulating red blood cell numbe

154 Aberrant, neovascular retinal blood vessel growth is a vision-threatening complication

155 factor (VEGF) is a key regulator of abnormal blood vessel growth.

156 he paravascular spaces (PVS) around cerebral blood vessels has been controversial.

157 ucture located on the luminal surface of all blood vessels, has been found to be integral to regulati

158 ion (OEF), or thickness after the ophthalmic blood vessels have been closed for a substantial interva

159 20th century, the repair and replacement of blood vessels have been key to treating acute injuries,

160 paired stability of intestinal microvascular blood vessels, hemorrhage, and death.

161 unodeficient mice generated fewer functional blood vessels (i.e., anastomosed with the host vasculatu

162 results from the effects of adjacent mutant blood vessels (i.e., cell-non autonomous).

163 The number of blood vessels identified with PVC on pCLE was significan

164 rrounding a tumor, including the surrounding blood vessels, immune cells, fibroblasts, signaling mole

165 roadly expressed on the luminal face of most blood vessels in adult vertebrates, yet its function on

166 ugh there was a significant proliferation of blood vessels in areas of vasoconstriction (angiogenesis

167 tance in severe asthma, and in remodeling of blood vessels in cancer and atherosclerotic vascular dis

168 omated segmentation pipeline of pathological blood vessels in CT images acquired with or without the

169 high-contrast and high-resolution images of blood vessels in deep tissues.

170 a viable approach to protect the vulnerable blood vessels in diabetes mellitus.

171 Despite many reports about pulmonary blood vessels in lung fibrosis, the contribution of lymp

172 vation and the subsequent aberrant growth of blood vessels in mice with ischemic retinopathy.

173 e infarcts, reactive astrocytes, and damaged blood vessels in multi-infarct dementia when compared to

174 eferentially localized in close proximity to blood vessels in physiological human dental pulps.

175 become adipocytes controls the formation of blood vessels in the bone marrow, and also regulates the

176 helial cells are distributed adjacent to the blood vessels in the brain dura mater of rats.

177 We found that the angiogenic growth of CNS blood vessels in the brain of Mfsd7c-KO embryos was inhi

178 Blood vessels in the central nervous system (CNS) develo

179 The blood vessels in the central nervous system (CNS) have a

180 ught to form via angiogenesis from preformed blood vessels in the cephalic mesenchyme.

181 n the construction of functional human-mouse blood vessels in the grafts that promoted cell survival

182 ision loss, is caused by damage to the small blood vessels in the retina.

183 PE) and on oxygen and nutrients delivered by blood vessels in the underlying choroid.

184 SC is relevant and eventually can reach the blood vessels in the vascularized dermis.

185 othelium supported the formation of perfused blood vessels in vivo.

186 dothelial cells and induced mispatterning of blood vessels in zebrafish.

187 mice, virus dissemination to major maternal blood vessels, including the aorta, resulted in a periph

188 LinTT1-NWs homed to CD31-positive tumor blood vessels, including to transdifferentiated endothel

189 rosis, alleviates solid stress, decompresses blood vessels, increases CTL infiltration, and decreases

190 ctions and in the cytosol, supporting normal blood vessel integrity and development.

191 munofluorescence showed albumin leakage from blood vessels into the neural retina, and electron micro

192 Leakage from blood vessels into tissues is governed by mechanisms tha

193 vated serum creatine kinase, heart dilation, blood vessel irregularity and respiratory failure with c

194 Edema stemming from leaky blood vessels is common in eye diseases such as age-rela

195 ng contractile nature; similarly, ECM lining blood vessels is highly elastic in order to sustain the

196 mechanisms that regulate the permeability of blood vessels is of critical importance for developing t

197 eta-amyloid (Abeta) deposits around cerebral blood vessels, is a major contributor of vascular dysfun

198 In rodent blood and isolated blood vessels, it has been reported that inhibition of C

199 their dysfunction causes pathologies due to blood vessel leakage.

200 Detection of the pathologic placental blood vessel lesion decidual vasculopathy (DV) has been

201 Also, 4f disrupted the blood-vessel-like assembly formed by human umbilical-vei

202 pancreatic adenocarcinoma, poorly-permeable blood vessels limit the intratumoral permeation and pene

203 lgorithm to delineate large as well as small blood vessels locally using 3-D spatial information and

204 ly, and incorporates spatially heterogeneous blood vessel lumen and interstitial permeabilities to ge

205 nts of all mammalian elastic tissues such as blood vessels, lung and skin, and are critically importa

206 nges and imply that therapeutic targeting of blood vessels may restore aged endocrine tissue function

207 We also discuss the potential role of blood vessel metabolism in regulating immune cell traffi

208 etically null for Prnd revealed impaired CNS blood vessel morphogenesis and associated endothelial ce

209 Abnormal control of blood vessel morphogenesis and maturation is linked to t

210 The CNS-specific genes that regulate blood vessel morphogenesis in development and disease re

211 associated with vasculature development and blood vessel morphogenesis signaling pathways were ident

212 n vascular homeostasis that directly affects blood vessel morphogenesis, angiogenesis, and tissue per

213 erentially expressed genes (DEGs) related to blood vessel morphogenesis.

214 s linked to developmental processes, such as blood vessel morphogenesis.

215 erein extensive proangiogenic alterations in blood vessel morphology and metabolic alterations underl

216 oncomitant decrease in the area of the fetal blood vessel network in the labyrinthine zone, suggestin

217 ic lethality due to the atrophy of the fetal blood vessel network in the placenta.

218 ructural similarity of the lymphatics to the blood vessel network, the lack of lymphatic-specific bio

219 cell proliferation and turnover and modulate blood vessel networks in xenograft mouse models in vivo.

220 characterizing intercellular colocation with blood vessel networks.

221 tholog in zebrafish, and we observed reduced blood vessel numbers and integrity in the eye and increa

222 Lztr1 deletion in blood vessels of adult mice leads to abnormal vascular l

223 Spinal cord blood vessels of CMH-treated mice showed reduced express

224 The blood vessels of the brain are lined with endothelial ce

225 s can grow instead by hijacking pre-existing blood vessels of the surrounding nonmalignant tissue.

226 yloid known in humans, as it can be found in blood vessels of the upper body in virtually everybody o

227 the luminal endothelial cells of the tumour blood vessels or extravasates into the tumour interstiti

228 s, between tightly packed cells, and between blood vessels or nerve bundles and their associated base

229 t of self-organizing three-dimensional human blood vessel organoids from pluripotent stem cells.

230 Use of these blood vessel organoids to model diabetic vasculopathy le

231 Human blood vessel organoids transplanted into mice form a sta

232 taneous fat was cultured in vitro to promote blood vessel outgrowth prior to implantation into immuno

233 or infiltration (P = .0044) and hyperplastic blood vessels (P = .0005).

234 gered transient vascular leak in spinal cord blood vessels, particularly in white matter, which was a

235 e demands dynamic navigation through complex blood vessel pathways and accurate placement of an inter

236 The endothelial glycocalyx regulates blood vessel permeability and homeostasis.

237 Aberrant formation of blood vessels precedes a broad spectrum of vascular comp

238 However, their formation in inflamed blood vessels produces a scaffold that supports thrombos

239 Retinal blood vessels provide information on the risk of cardiov

240 egrity of endothelial cells (ECs) lining the blood vessels regulates the inflammatory response.

241 Instead, Abeta deposits in cortical blood vessels reminiscent of cerebral amyloid angiopathy

242 el roles for the ANGPT2 N-terminal domain in blood vessel remodeling, tumor growth, metastasis, integ

243 r endothelial cells, which line the lumen of blood vessels, represent a critical barrier for a bacter

244 rates sensory information from the heart and blood vessels, respond to incoming afferent inputs with

245 iency induces pruning of immature-like tumor blood vessels resulting in delayed tumor growth and meta

246 (AVMs) have an inherent capacity to form new blood vessels, resulting in excessive lesion growth, and

247 ound in humans, where disruption of maternal blood vessels results in maternal blood bathing the sync

248 diabetic retinopathy, overgrowth of retinal blood vessels results in the formation of pathological n

249 glucose transporter type 1-positive cerebral blood vessels, reverted cerebral vasoreactivity, and HFD

250 During angiogenesis, new blood vessels sprout and grow from existing ones.

251 aortic arch development, hyperactive ectopic blood vessel sprouting, and aberrant patterning of the b

252 get of YAP in endothelial cells (ECs) of new blood vessel sprouts and that YAP deficiency in mice dow

253 tal model, permitting exposure of developing blood vessel sprouts to multiple combinations of diverse

254 rse pathways in LGCs, promoting survival and blood vessel stabilization while suppressing cell death

255 gy of whole mouse brain and kidney including blood vessel structure is reconstructed by deep tissue o

256 These are often caused by changes in blood vessels, such as the expansion of the basement mem

257 Blood vessels support tumours by providing nutrients and

258 nt mice revealed a decrease in the number of blood vessels surrounded by ALDH1(high) or Bmi-1(high) c

259 ayer arteriole-scale human tissue-engineered blood vessels (TEBVs) by plastic compression.

260 ells (ECs) are fundamental components of the blood vessels that comprise the vascular system; facilit

261 t is characterized by enlarged and irregular blood vessels that often lead to cerebral hemorrhage.

262 pericytes) are integral components of brain blood vessels that play important roles in vascular form

263 s system (CNS) contains a complex network of blood vessels that promote normal tissue development and

264 atopoietic stem-cell niche form a network of blood vessels that regulates blood-cell traffic as well

265 re, we discuss the unique characteristics of blood vessels, the heart, and the kidney of giraffes and

266 of the review discusses models for mimicking blood vessels, the respiratory tract, the gastrointestin

267 reshape, destroy, or integrate into existing blood vessels, thereby affecting oxygenation, perfusion,

268 of scales between advection and diffusion in blood vessels, this method becomes practically numerical

269 /-) mutants prominently show vasodilation of blood vessels through increased vascular thickness in th

270 shown that two cells that commonly home from blood vessel to tissue-T cells and hematopoietic stem an

271 rentially in human bladder cancer-associated blood vessels to find novel biomarkers and mechanisms in

272 Recruitment of leukocytes from blood vessels to inflamed zones is guided by biochemical

273 ay that enables the generation of functional blood vessels upon vasculogenic differentiation of DPSCs

274 The blood vessels vascularizing the central nervous system e

275 ide that we exploit for in vitro and in vivo blood vessel vasodilation.

276 V volume (RV(EV)), distal pulmonary arterial blood vessel volume (arterial BV5: vessels <5 mm(2) in c

277 tic agent to be effective, it must cross the blood vessel wall to reach cancer cells in adequate quan

278 The adventitia, the outer layer of the blood vessel wall, may be the most complex layer of the

279 Abnormal HA accumulation within blood vessel walls is associated with tissue inflammatio

280 yloid deposition in the brain parenchyma and blood vessel walls, potentially resulting in cerebral am

281 , which are known to damage the integrity of blood vessel walls.

282 Mural cell coverage of the blood vessels was also reduced in betaA-Akt1WT/flx skin

283 Microglial repair of leaky blood vessels was blocked by a peptide that inhibits the

284 Because cartilage does not have blood vessels, we studied ear AVMs to determine if overg

285 in the perivascular niche close to remaining blood vessels were enriched.

286 Blood vessels were imaged in mice and pigs.

287 Nonetheless, CNS blood vessels were intact, without hemorrhage.

288 reases in the intensity of CD31, a marker of blood vessels, whereas the intensity of gamma-H2AX, a ma

289 interstitial pressure and decompressed tumor blood vessels, which are both associated with increased

290 t, perivascular invasiveness along remaining blood vessels, which co-opts vessels in a VEGF-independe

291 microenvironment relies on the formation of blood vessels, which go beyond the regulation of metabol

292 Leakage of retinal blood vessels, which is an essential element of diabetic

293 the pharyngeal arches form a plexus of small blood vessels, which remodels into the PAAs by 35 somite

294 iogenic drugs targeting specifically nascent blood vessels with a mode-of-action complementary to VEG

295 a model showing accelerated formation of new blood vessels with a reduced inflammatory response imped

296 Blood vessels with high B55alpha counter cell stress con

297 They promote formation of functional blood vessels, with a density as high as ~220 vessels mm

298 To quantify blood vessels within bone, an innovative approach was de

299 otein expression to the tunica adventitia of blood vessels within the tumor.

300 icated by tumor-associated or normal stromal blood vessels yet its significance may differ from the o