ライフサイエンスコーパス: bone metabolism

1 f2 activation by disruption of Keap1 impacts bone metabolism.

2 her irisin lacking affects glucose/lipid and bone metabolism.

3 understanding of the role of this pathway in bone metabolism.

4 re important for coagulation, signaling, and bone metabolism.

5 D], which regulates calcium, phosphorus, and bone metabolism.

6 well as some already known to be relevant to bone metabolism.

7 oduce a wide variety of factors important to bone metabolism.

8 e inducers, are associated with disorders of bone metabolism.

9 esis and lipid metabolism) and indicators of bone metabolism.

10 ted and appears to have an important role in bone metabolism.

11 a basis for further studies on 18F-fluoride bone metabolism.

12 of various cellular interactions, including bone metabolism.

13 protein and potassium to predict markers of bone metabolism.

14 ne mineral density and peripheral markers of bone metabolism.

15 lactinemia did have an impact on the rate of bone metabolism.

16 sine phosphorylation is a major regulator of bone metabolism.

17 metric parameters and biochemical markers of bone metabolism.

18 xial and peripheral bone mass and markers of bone metabolism.

19 nts, which may contribute to disturbances in bone metabolism.

20 ietary protein may have different effects on bone metabolism.

21 d that sex steroids have profound effects on bone metabolism.

22 udy of the effects of estrogen deficiency on bone metabolism.

23 ines (50%) mentioned the need to investigate bone metabolism.

24 (FSH) has an impact on body composition and bone metabolism.

25 progression, immune response activation and bone metabolism.

26 ant modulator of mineral ion homeostasis and bone metabolism.

27 he sympathetic nervous system (SNS) mediates bone metabolism.

28 trate a biological link between selenium and bone metabolism.

29 flammation, wound healing, angiogenesis, and bone metabolism.

30 and dependencies among cells that coordinate bone metabolism.

31 2, an adiposity and diabetic gene, regulates bone metabolism.

32 for LIFRbeta lead to a syndrome with altered bone metabolism.

33 amin D3 are known to play important roles in bone metabolism.

34 ytokines, which indirectly impact energy and bone metabolism.

35 ood coagulation, vascular calcification, and bone metabolism.

36 bout its potential role in breast cancer and bone metabolism.

37 odstream can hence be indicative of abnormal bone metabolism.

38 E4D, and SATB2, which all closely related to bone metabolism.

39 ts and osteoclasts, suggesting a key role in bone metabolism.

40 clear factor kappa B ligand (RANKL) and thus bone metabolism.

41 with low levels of NH4 (+) and no change in bone metabolism.

42 olism have been related to direct effects on bone metabolism.

43 e link between pediatric nephrolithiasis and bone metabolism.

44 ink between phosphatidylserine synthesis and bone metabolism.

45 ious proteins involved in blood clotting and bone metabolism.

46 ontributing to region-specific regulation of bone metabolism.

47 antipsychotic-induced hyperprolactinemia on bone metabolism.

48 that these autoantibodies directly influence bone metabolism.

49 rst report describing a role for XLalphas in bone metabolism.

50 ctive outcomes, neuroendocrine function, and bone metabolism.

51 tein synthesis, carbohydrate homeostasis and bone metabolism.

52 ith calcium to improve calcium retention and bone metabolism.

53 e carefully evaluated as they may impinge on bone metabolism.

54 g the effects of irisin on glucose/lipid and bone metabolism.

55 MD, BMC, T scores, or biochemical markers of bone metabolism.

56 one and may play a role in the regulation of bone metabolism.

57 of interest, termed K(i), reflects regional bone metabolism.

58 signaling network plays an essential role in bone metabolism.

59 one product of the thyroid gland involved in bone metabolism(3), is also produced by atrial cardiomyo

60 TNF on PTHrP-induced changes in calcium and bone metabolism, a murine tumor model of hypercalcemia w

61 athyroid hormone (PTH), a major regulator of bone metabolism, activates the PTHR1 receptor on the ost

62 ed signals have emerged as key regulators of bone metabolism, although their mechanisms of action hav

63 umbar spine bone mineral density (LSBMD) and bone metabolism among Thai adolescents with perinatally

64 molecular chaperones for collagen type I and bone metabolism and a crucial role of HSP47 in the KDELR

65 an important role in calcium homeostasis and bone metabolism and also affects many other cellular reg

66 -4 (DPP-4) have shown pleiotropic effects on bone metabolism and anti-inflammatory properties.

67 a promising noninvasive method for measuring bone metabolism and bone blood flow.

68 than weight gain and obesity alone modulates bone metabolism and can therefore influence alveolar bon

69 rix metallopeptidase 13) plays a key role in bone metabolism and cancer development, but has no known

70 (TCO-BP, 2) that binds to regions of active bone metabolism and captures functionalized tetrazines i

71 ty for investigating the correlation between bone metabolism and clinical outcome during bisphosphona

72 as now been implicated in regulating fat and bone metabolism and cognition.

73 ement based on a blood biomarker measures of bone metabolism and dual-energy X-ray absorptiometry ima

74 ET allows noninvasive evaluation of regional bone metabolism and has the potential to become a useful

75 associated with major changes in calcium and bone metabolism and in bone mineral status before and af

76 that phenytoin is associated with changes in bone metabolism and increased bone turnover.

77 In animal studies, TCDD exposure impairs bone metabolism and increases fragility.

78 ctors may disrupt the physiologic balance in bone metabolism and lead to the pathologic loss of alveo

79 blood and urine and are used to investigate bone metabolism and manage bone diseases.

80 (18)F-fluoride PET quantitatively images bone metabolism and may serve as a pharmacodynamic asses

81 Osteocytes play an important role in bone metabolism and mineral homeostasis, but its role in

82 3, collagenase-3) plays an essential role in bone metabolism and mineral homeostasis.

83 insic mechanism that is important in both MM bone metabolism and normal physiology.

84 elopment centered primarily on its effect on bone metabolism and not on its antineoplastic activity.

85 ion (real-time PCR) assessment of markers of bone metabolism and oxidative stress.

86 of research in which these nutrients affect bone metabolism and skeletal health.

87 ect of inhaled glucocorticosteroids (ICS) on bone metabolism and subsequent osteoporosis is controver

88 ways and also influence insulin sensitivity, bone metabolism and sympathetic outflow; all of these ha

89 R) signaling regulates both inflammation and bone metabolism and that the receptor activator of NF-ka

90 ghts contribute to a better understanding of bone metabolism and the anabolic function of PTH.

91 we tested the effect of anti-DKK1 therapy on bone metabolism and tumor growth in a SCID-rab system.

92 sociated local factors on cross-talk between bone metabolism and tumour biology.

93 d from normal and tumor cells that regulates bone metabolism and vascular tone, is a naturally occurr

94 lterations in behavior, insulin sensitivity, bone metabolism, and acquired immune responses.

95 ctivated receptor gamma (PPARgamma) regulate bone metabolism, and because steroid receptor coactivato

96 turbances of glucose, insulin resistance and bone metabolism, and body weight changes.

97 amines insights into molecular mechanisms of bone metabolism, and discusses the prevention and treatm

98 R - ZNF521 and SEMA3A, which are involved in bone metabolism, and HLA-DRA and CHIRL1, which are impli

99 er understanding of the neural regulation of bone metabolism, and importantly and of clinical relevan

100 tamin K has been suggested to have a role in bone metabolism, and low vitamin K intake has been relat

101 d on the release of markers of inflammation, bone metabolism, and oxidative stress in diabetic rats.

102 -FMS play a key role in the immune response, bone metabolism, and the development of some cancers.

103 one mineral density, biochemical measures of bone metabolism, and the incidence of nonvertebral fract

104 uated cortisol and growth hormone secretion, bone metabolism, and vitamin D-receptor alleles.

105 thereby potentiate altered lipid metabolism, bone metabolism, and weight status of transplant recipie

106 Pathological alterations in the balance of bone metabolism are central to the progression of inflam

107 ation, but roles of specific phosphatases in bone metabolism are largely unknown.

108 However, the effects of CLP on bone metabolism are unknown.

109 al functions, including glycemic control and bone metabolism, are highly influenced by the body's int

110 ) mice showed phenotypes related to impaired bone metabolism as increased carboxy-terminal collagen c

111 bed mechanism may contribute to the abnormal bone metabolism associated with IBD.

112 o-activator of Nox2 is lost, to characterize bone metabolism at 6 weeks and 2 years of age.

113 ess play a key role in switching the mode of bone metabolism between formation and resorption.

114 d hormone (PTH), which is a key regulator of bone metabolism but also of HSC activity.

115 hysiologic testosterone levels may influence bone metabolism, but only subphysiologic levels signific

116 tamins K2 and D3 exhibit anabolic effects on bone metabolism, but their effectiveness in guided bone

117 m studies show no effects of these agents on bone metabolism,but long-term data are not available.

118 Pathophysiological bone metabolism can be induced via exposure to LPS and d

119 Alterations in bone metabolism can result in decreased bone mass (osteo

120 Three genes potentially contributing to bone metabolism, CCR3 (chemokine receptor 3), HDC (histi

121 SOST in the adult bone and had an impact on bone metabolism, consistent with the model that the VB n

122 tonin and glucocorticoids, known to modulate bone metabolism, could have opposite actions on bone cel

123 nsive and rapid point-of-care (POC) tool for bone metabolism detection and prognostics.

124 ric measurements, laboratory measurements of bone metabolism, disease activity, dietary intake, and p

125 advances in our understanding of calcium and bone metabolism during human pregnancy and lactation and

126 participate in the regulation of calcium and bone metabolism during lactation.

127 n increased in response to two modulators of bone metabolism, estradiol and intermittent mechanical l

128 he prevailing theory is that an imbalance in bone metabolism favours microdamage accumulation over it

129 Vitamin D plays crucial roles in bone metabolism, growth, and immune response during crit

130 necrosis factor [TNF]-alpha) that may alter bone metabolism have been previously found to be increas

131 mproved resolution, sensitivity and speed in bone metabolism imaging -- without any of the health ris

132 ormation and resorption were used to measure bone metabolism in 14 Caucasian female patients with sch

133 Correcting acidosis also improves bone metabolism in CKD and hence should be a goal of the

134 urnover markers and other factors related to bone metabolism in CKD.

135 study was to identify genes associated with bone metabolism in GC-treated mice, by performing a micr

136 he effect of resistance exercise training on bone metabolism in heart transplant recipients.

137 curate interpretation of changes in regional bone metabolism in response to treatment.

138 flurbiprofen nitroxybutylester (HCT1026), on bone metabolism in vitro and in vivo.

139 previously that caffeine intake could affect bone metabolism in vivo.

140 mal progenitor cells and used to investigate bone-metabolism in vitro.

141 calcemia and a relatively mild disruption of bone metabolism, in this case complicated by severe auto

142 , and total body; blood and urine markers of bone metabolism; incident falls, clinical fractures, and

143 Serum was analyzed for indices of bone metabolism including calcium, 25-hydroxyvitamin D,

144 , 3-fold decrease of polyphenols involved in bone metabolism, including m-coumaric acid, catechin der

145 tive sleep apnoea syndrome (OSAS) may affect bone metabolism increasing the risk for secondary osteop

146 Furthermore, bone metabolism is altered by a high-protein acidogenic

147 Conventional in vivo imaging of bone metabolism is dominated by gamma-ray bone scintigra

148 But a physiological role of SIRT3 in bone metabolism is not known.

149 e tissues, yet the role of these proteins in bone metabolism is not well known.

150 In bone metabolism, it has been shown that numerous TNF fam

151 Apart from the effects of vitamin D on bone metabolism, it is also known for its immunomodulato

152 To preserve or restore normal bone metabolism, it is crucial to determine the mechanis

153 cally obvious are significant alterations in bone metabolism leading to osteoporosis, which can affec

154 en of calcium and phosphorus due to abnormal bone metabolism; low levels of circulating and locally p

155 In conclusion, CANA affects bone metabolism mainly via the "glucose restriction stat

156 rotein), erythrocyte sedimentation rate, and bone metabolism markers (osteoprotegerin [OPG], osteocal

157 , GIP, GIPR-An, glucagon-like peptide 2, and bone metabolism markers by frequent blood sampling durin

158 Bacterial challenge decreased bone metabolism markers in all groups (P < 0.01).

159 cant improvement in bone mineral density and bone metabolism markers.

160 Lead toxicity and bone metabolism may be involved in ALS pathophysiology.

161 on associations with intermediate markers of bone metabolism may not reflect optimal levels for other

162 in D, in addition to its established role in bone metabolism, may regulate the immune system and affe

163 oride metabolic values as well as changes in bone metabolism measured by SUV and Patlak analysis were

164 The role of C-PC on bone metabolism needs revelation.

165 ), and may be related to increased levels of bone metabolism observed in ace(ti282a)/fgf8 heterozygot

166 expression thus contributing to the abnormal bone metabolism observed in IBD.

167 ntly reduced alveolar bone loss and improved bone metabolism of OVX-periodontitis rats as compared wi

168 signaling pathways play in the regulation of bone metabolism offers great promise for the development

169 a direct impact on inflammatory response and bone metabolism on the development of ONJ-like lesions.

170 Like its role as a regulator of bone metabolism, OPG also influences processes in the im

171 ders has been associated with alterations of bone metabolism, or of bone maturation, as well as with

172 ion (tumor necrosis factor [TNF]-alpha), and bone metabolism (osteocalcin [OC], carboxy-terminal coll

173 In addition to its effects on bone metabolism, osteoprotegerin (OPG), a soluble member

174 n the expression of inflammatory markers and bone metabolism proteins by human periodontal ligament s

175 s were changes in LSBMD, LSBMD z-scores, and bone metabolism-related biomarkers (25-hydroxyvitamin D

176 P) and immunohistochemical staining for five bone metabolism-related markers (osteocalcin [OCN], oste

177 eases in LSBMD, and significant decreases in bone metabolism-related markers were observed among our

178 Calcium and bone metabolism remain key concerns for space travelers,

179 rchitecture, gut microbiota, metabolites and bone metabolism remains poorly understood.

180 We investigated changes in bone metabolism, renal processing of Ca(2+), and express

181 Physiologic bone metabolism requires the coupled activities of bone

182 However, the effect of adiponectin on bone metabolism shows contradictory results according to

183 PTH1R regulates bone metabolism, signaling mainly through G(s) and G(q/1

184 d glycation end products, leading to altered bone metabolism, structure, and strength.

185 ." Secondary outcomes included biomarkers of bone metabolism, such as maternal plasma concentrations

186 veral indirect effects of glucocorticoids on bone metabolism, such as suppression of production of in

187 We also demonstrated changes in markers of bone metabolism suggestive of bone formation, but no cha

188 ticosteroid administration may be better for bone metabolism than continuous use of orally administer

189 favorable changes in biochemical indexes of bone metabolism than does calcium supplementation alone.

190 Renal osteodystrophy (ROD) is a disorder of bone metabolism that affects virtually all patients with

191 corticoid (GC) excess induces alterations in bone metabolism that weaken bone structure and increase

192 lB-p52 heterodimer, plays important roles in bone metabolism through an unknown mechanism.

193 ormone/Insulin-like growth factor 1 axis and bone metabolism to a larger extent and weight gain via e

194 to be critical for hemostasis, immunity, and bone metabolism via its role in integrin activation.

195 ere initially identified as having a role in bone metabolism via the analysis of their phenotype afte

196 released during inflammation plays a role in bone metabolism via the H2 receptor, stimulating bone re

197 of IL-23 in the development of arthritis and bone metabolism was studied using systemic IL-23 exposur

198 To further determine the role of OF45 in bone metabolism, we generated a targeted mouse line defi

199 ased on leptin's recently discovered role in bone metabolism, we hypothesized these glands were the s

200 Changes in serum biochemical markers of bone metabolism were also assessed.

201 Clinical markers of calcium and bone metabolism were measured.

202 Cathepsin-K is an enzyme involved in bone metabolism which may make this feature important fo

203 beneficial effects on plasma cholesterol and bone metabolism while maintaining antiestrogenic activit

204 health, and drug use factors known to affect bone metabolism with incident nonvertebral fractures.

205 es (cytokines, inflammation, oxidant stress, bone metabolism) with osteonecrosis in patients with sic

206 The presence of biomarkers of bone metabolism within saliva and their correlation with