ライフサイエンスコーパス: both

1 y synchronous, asynchronous, or a mixture of both.

2 ir variance, whereas high-dose AMPH expanded both.

3 ng personal or family history of cancers, or both.

4 dies to eliminate neutrophils, monocytes, or both.

5 ed in Type 2 Hi asthma, where high levels of both 15LO1-PEBP1 and LC3-II are seen in HAECs, in associ

6 We demonstrate that this method is suited to both 3D structure determination and correlative light/el

7 selectivity of the reaction is attributed to both a pai-pai stacking effect and the steric hindrance

8 severe disease after virus infection include both a paucity of protective vaccines as well as the ear

9 s suggest swine influenza viruses containing both a stabilized HA and alpha-2,6 receptor binding in t

10 value = 0.0028), which has been reported as both a tumor suppressor and an oncogene.

11 Patients exercised at both absolute (0, 5, 10, 15 W) and relative (40, 60, 80%

12 transformations and have been widely used in both academic and industrial settings.

13 Therefore, both activation and inactivation of PVCV occurred in age

14 diversity of HIV-1 is a major challenge for both active and passive immunization.

15 ndrome corona virus 2 pneumonia is linked to both acute respiratory distress syndrome and systemic hy

16 s-reactive warhead-were designed to leverage both affinity and reactivity.

17 rmore, FICZ-induced MMP1 expression required both AHR and ARNT, demonstrating that the AHR-ARNT trans

18 e relationship between handgun ownership and both all-cause mortality and suicide (by firearm and by

19 ld not metabolize either glycogen or starch (both alpha-glucans) or other polysaccharides tested.

20 Both amoeboid and ramified cells from mesial temporal lo

21 We examined both an optimal observer model and an approximate Bayesi

22 ecies that are key invertebrate predators in both aquatic (as larvae) and terrestrial ecosystems (as

23 d particularly the NAWH requires considering both atmospheric and oceanic mechanisms.

24 ism for phenomena observed in experiments on both atrial and ventricular cardiac cells.

25 tabaga/+;octbeta1r/+ flies perform poorly in both aversive and appetitive conditioning, while individ

26 The duration of VEGF exposure influenced both barrier relaxation and anti-VEGF-mediated closure.

27 .5% at 26 weeks in the CGM group and 8.9% at both baseline and 26 weeks in the BGM group (adjusted be

28 For nonantioxidants, vitamin B12 use both before and during chemotherapy was significantly as

29 We observed variability both between and within examiners in the diagnosis of pl

30 Both BPV-1 and HPV-31 Y102E are similar in that neither

31 In both C. elegans and human cancer cells, ether-lipid synt

32 hic study (12 crystal structures), involving both CA II and a soluble CA IX mimetic (CA IX-mimic), re

33 ew prospective hallmarks that might apply to both cancer and wound healing and discuss how wounding,

34 rface has the least area and free energy, in both capsids.

35 e survival across treatments, expecting that both carbon stability and survival probability would inc

36 d and selected mutant forms of uPlm that are both catalytically active and insensitive to alpha2-AP i

37 Ccl17(E/+) reporter mice; it also exploited both CCL17-dependent and unique CCL17-driven inflammator

38 apable of antigen processing and priming for both CD4(+) and CD8(+) T cells and of the direct orchest

39 Perforin contributed to both CD8+ and CD4+ CAR T cell cytotoxicity but was not r

40 In both cell types, promoters with high basal H3K4me2/3 act

41 Both CFS and PAC networks coupled theta and alpha oscill

42 ification and to assess genetic diversity of both Chilean and Spanish germplasm collections.

43 Ventralization in Ankmy2 knockout requires both cilia and Gli2 activation.

44 and PI therapy, which significantly reduced both class I and II HLA antibodies and increased the lik

45 -rim radiomic features were most relevant to both classifications (p <= 0.044).

46 The HLA system plays a pivotal role in both clinical applications and immunology research.

47 which combines the synergistic properties of both CNTs and AuNPs, represents a promising signal ampli

48 of CO(2) to chemical feedstocks, which uses both CO(2) and renewable energy(3-8).

49 Site-directed mutagenesis of both cofilin and actin revealed residues critical for su

50 of several essential neural nodes engaged in both cognitive and motor processing.

51 Both complications and preoperative patient risk have be

52 ution studies in healthy rats confirmed that both compounds are BBB permeable and that bladder accumu

53 With both conceptual and empirical support, we argue that thr

54 C9orf72 and SMCR8 both contain longin and DENN (differentially expressed i

55 Despite both control and ACC2 iKO mice exhibiting a similar obes

56 uced substantial T-cell depletion, impacting both conventional T cells (T(conv)) and T(regs), subsequ

57 e that VDR(-/-) and VDD significantly reduce both corneal epithelial wound healing and nerve density

58 ends and spatial structures in SOC and TN in both croplands, and the fertilization effect appeared mo

59 PFHxS lowered thyroid hormone levels in both dams and offspring in a dose-dependent manner, but

60 of darT(Mtb) , but simultaneous deletion of both darT(Mtb) -darG(Mtb) does not alter viability of Mt

61 Venous thromboembolism (VTE), which includes both deep venous thrombosis and pulmonary embolism, is a

62 ep heights are displayed and shown to define both deformed and recovered structures.

63 Both depletion of Pyk2 and treatment with a Pyk2 kinase

64 es, we studied the formation and exchange of both dialdehydes and triamines of two different [2 + 3]

65 FtsK translocates double-stranded DNA until both dif recombination sites are placed at mid cell for

66 The optimal concentration of both drugs for BAT was determined as 5 mg/mL.

67 ffected by species richness and lake size in both ecoregions and alkalinity and total phosphorus in n

68 -experienced participants with resistance to both efavirenz and lamivudine, 32 (35.6%) of whom were s

69 g cardiac pressure overload, contributing to both electrical and structural remodeling.

70 The evolutions for both emission spectra and hardness of molten zone were r

71 e digestion affects the compounds content in both encapsulated and unencapsulated extracts.

72 or (P < .001) to piperacillin/tazobactam for both endpoints: day 28 all-cause mortality was 15.9% wit

73 he promoter activation rate is influenced by both enhancer and promoter sequences, whereas Pol II loa

74 Both epiboly and microtubule defects were partially rest

75 echanism conferring tamoxifen resistance via both ERalpha dependent and independent pathways.

76 Model discrimination and calibration were both evaluated.

77 d scaling relations in the delay suffered by both event participants and other citizens doing their u

78 2 is a remarkably mature galaxy cluster with both evolved stellar populations in the member galaxies

79 Approximately 40% of patients in both exercise dosing regimens were classified as VO(2)pe

80 Mice that lack TLR9 are deficient in both exercise-induced activation of AMPK and plasma memb

81 IG provides consensus recommendations to aid both expert and non-expert clinicians in the diagnostic

82 tant class of plant signalling molecule with both external rhizospheric and internal hormonal functio

83 .5) in Delhi, highlighting the importance of both external transport and local emissions to PM(2.5) p

84 of 12 subjects with manifest keratoconus in both eyes (KCE cohort), 9 subjects with very asymmetric

85 ce of chronic PAMM lesions was evaluated for both eyes by the revision of cross-sectional OCT images

86 The combination of both factors had no additional effect on the bioactive p

87 10 healthy participants (each group included both females and males).

88 t confers the capability of interacting with both filament types onto melanophilin.

89 Our results, both for all CIDP and typical CIDP presentations, suppor

90 al lymphangiectasia in transplanted kidneys, both from pediatric donors.

91 onomies and biodiversity, yet stands to lose both from present exposure to natural hazards, and futur

92 Both full-length TDP-43 and its CTD are also known to fo

93 ed by the HOTAIR regulatory element and that both function in regulating glioma cell sensitivity to T

94 The study evaluates both functional and anatomical outcomes of retinal detac

95 gle SOD5-like SOD rather than a pair, and in both fungi, this SOD was induced by Fe starvation.

96 cancer cells, proved to be able to stabilize both G-quadruplexes and R loops and showed a potent cell

97 well understood, it is believed to comprise both genetic and environmental factors.

98 Both genetic programs arising from oncogenic events and

99 tricine does not affect the murine b-wave in both genotypes, most likely because of chelating amino a

100 We have previously demonstrated that both GLP-1 and CCK are produced in the endocrine pancrea

101 nhibitors of glucose transporters, targeting both GLUT1 and GLUT3.

102 Measurements were collected in both greenhouse and field environments, with plants expo

103 it progressively improved up to month 18 in both groups (Cit-B12, p < 0.0001; controls, < 0.0001-0.0

104 e index (API) were significantly improved in both groups 3 and 6 months after SRP.

105 1-42 was equally effective in discriminating both groups from frontotemporal lobar degeneration.

106 Both groups showed similar levels of insulin sensitivity

107 ne, whereas visual outcomes were similar for both groups.

108 tance visual acuity (CDVA) was calculated in both groups.

109 the two carbon atoms of the L->C(2) complex both have carbene character.

110 In conclusion, both HBsAg production and HDV replication are effectivel

111 ights are relevant to CD81's varied roles in both health and disease.

112 ed by the CPSF30-hFip1 complex in vitro, and both hFip1 binding sites in CPSF30 can support polyadeny

113 -symmetry striped phase that is disrupted at both high and low extremes of chemical potential.

114 plete suppression of spontaneous seizures in both hippocampi.

115 y State Type IV-B, was the most prevalent in both HIV-negative (38% at baseline, 30% at the follow-up

116 of tens of nanoamperes, which flowed through both homogeneous and non-homogeneous base-pair sequences

117 improvements than non-teaching hospitals for both hospital-level (safe patient handling programs and

118 April 1, 2020, 1150 adults were admitted to both hospitals with laboratory-confirmed COVID-19, of wh

119 ic proline-rich domain to be dispensable for both HSP90 interaction and PDE6 activity.

120 Chronic stress in both humans and rodents induces a robust downregulation

121 Interleukin 22 (IL-22) signals via both IL-22 receptor alpha1 (IL-22Ralpha1) and the common

122 were separated and independently analyzed by both imaging and flow velocity analyses.

123 , accounting for a high proportion of EYS-RD both in autosomal recessive RP (23.4%) and autosomal rec

124 semialdehyde (alpha-AASA) and pipecolic acid both in brain and liver tissues, similar to the biochemi

125 50) in the ER, and measured its fluorescence both in dissociated ommatidia and in vivo from intact fl

126 ciated with increased incidence of diabetes, both in humans and in animal models.

127 and WLN5-6 were detected by NMR spectroscopy both in the presence and absence of Cu at a common inter

128 bosomal integrity following oxidative stress both in vitro and in cells to elucidate details of the i

129 s its aggregation, and inhibits its toxicity both in vitro and in vivo In this study, we investigate

130 rus-encoded VP3 antagonizes RNase L activity both in vitro and in vivo These studies highlight an eve

131 st, for short-stopping we found evidence for both individual plasticity (individuals decrease their m

132 at cell hyperpolarization and depolarization both induce persistent static elevation of cytoplasmic c

133 Brain structure in later life reflects both influences of intrinsic aging and those of lifestyl

134 s of white matter and clinical decline using both internal and external datasets.

135 omplete its life cycle, Chlamydia must evade both intracellular innate immune responses and adaptive

136 Two major mechanism hypotheses, both involving ESAA relief, were explored through quantu

137 in binding-impaired subunits, as we show for both kainate and GluA2 AMPA receptors.

138 -driven solid-density plasma-sources deliver both kinds of radiation, but mostly single modalities ha

139 t in field-selected larvae from India and in both lab-selected strains.

140 Both LF and NF groups had similar demographics, valve ar

141 or structure and sequence elements shared by both lineages.

142 otoxicity of melatonin was carried out using both live/dead and MTT assays.

143 4 variants are identified that contribute to both LOAD risk and age at onset of LOAD.

144 elationship between institutionalization and both lower intelligence quotient (IQ) and higher levels

145 s well as generic defences effective against both Ma549 and E. muscae.

146 For the diagnosis of early glaucoma, both macular and optic disc scans should be used.

147 rticogenesis during prenatal development, in both males and females.

148 lved in the production of specific sfRNAs in both mammalian and mosquito cells.

149 es Score per nurse ratio greater than 61 for both mean Nursing Activities Score per nurse ratio as we

150 information and in the underlying models of both measurements (bilinear for 3D images and trilinear

151 In somatic cells, these functions are both mediated by Scc1-cohesin, which in mitosis is relea

152 confidence gRNA cleavage sites identified by both methods.

153 -dose EPO triggered robust RBC production in both models.

154 ange of flowering land plant families and in both monocots and dicots.

155 l clones were detected in the circulation by both mRNA-based and genomic DNA-based sequencing.

156 In both murine and human tumor cells, HOTAIR-sbid impaired

157 69% were BRCA1+, 30% were BRCA2+, and 2% had both mutations.

158 nanohaloarchaeon-haloarchaeon association is both mutualistic and symbiotic; in this case, each micro

159 ic devices was associated significantly with both myopia and high myopia (OR, 2.43 and 2.31).

160 ntly localized in a punctate distribution in both N. benthamiana and maize (Zea mays) protoplasts.

161 clonal origin, as well as instances in which both NAT tissue and tumor tissue harbor a gain of the sa

162 t that (1) S-nitrosothiols covalently modify both NBT and TNBT, but only change the reduction potenti

163 Lack of precision in both neuroanatomical and clinical boundaries have likely

164 We identified and profiled both neuronal (glutamatergic and GABAergic) and nonneuro

165 er burden of premenopausal breast cancer for both new cases and deaths compared with higher income co

166 asses of brain endothelial cells (ECs) under both normal conditions and after deletion of Pdcd10 (Ccm

167 al regions, from 20 degrees to 40 degrees of both northern and southern latitudes, mostly in areas wi

168 rtation resources to underserved populations both now and in the future.

169 ly correlated with fasting plasma glucose in both obese mice and humans.

170 and at the flanking eRNA initiation regions, both of which are associated with mRNA expression QTLs.

171 igin of enantio- and diastereoselectivities, both of which are central to the burgeoning domain of st

172 ools (upper boundary of the 98.75% CI, 0.8), both of which were below the noninferiority margin (2 st

173 Intriguingly, both optogenetic excitation and inhibition of cerebellar

174 of ex vivo normothermic perfusion (EVNP) in both organ viability assessment and reconditioning is in

175 ynamics simulation approaches, we found that both OTUB1 and OTUB2 display a catalytic triad character

176 lant site were significantly associated with both outcomes (increased probing depth and bone loss).

177 ations were found for HDL and triglycerides (both p > 0.05).

178 unusual because it carries all the genes for both pathways.

179 nt protein kinase CPK3 is a key regulator of both pattern-triggered immunity and effector-triggered i

180 male brain, we map all inputs and outputs to both pC1d and pC1e.

181 First, we demonstrated through both PCR and immunostaining that mouse lymphatic muscle

182 e events, although mild, were more common in both peppermint oil groups (P < .005).

183 aluable for a first response assessment with both PET- and CT-based criteria.

184 gely in the phases in crystallography but in both phases and amplitudes in cryo-EM, and that half-map

185 Strains lacking both pilins are resistant to a broad panel of SSVs as we

186 The imaging readouts can be obtained in both preclinical models of diabetes mellitus and patient

187 mediated murine model of cardiac fibrosis in both preventive and therapeutic settings, as well as in

188 ectivity, even when the two substituents are both primary alkyl groups.

189 Image analysis of motile cell populations, both primary and cultured, typically reveals an intercel

190 and AR-V7 transcription activation required both PRMT5 and pICln but not MEP50.

191 Protein factors that mediate both processes, including the 5'-3' exonuclease Xrn1, ar

192 cantly enhances RIG-I mediated production of both proinflammatory cytokines and interferons.

193 s a pathogenic role for PAD enzymes in RA as both promoters and targets of the autoimmune response, a

194 G central conserved domain are protective in both prophylactic and postinfection animal models.

195 In mice, both prophylactic and therapeutic RDV improve pulmonary

196 te additional immune functions that may have both protective and pathological consequences.

197 We showed that lncRNAs are distinct from both protein-coding transcripts and genomic background n

198 atrix import for cPMP biosynthesis involving both proteins.

199 olving power depends on the uncertainties in both quantities.

200 year period, July 2007-April 2013, a time of both rapid ocean warming throughout the Gulf of Maine an

201 Both raw CPS and TPS were reported, as well as positivit

202 These cells, which express both RB and S18-2 at high levels, exhibited the potentia

203 The dual activation of both reaction partners, chiral Lewis-base activation of

204 ) chromosomes in high-fitness individuals of both reciprocal crosses, whereas maternal biases were la

205 overy of NPQ under equivalent intensities of both red and blue light.

206 ion of TRPC1 induced by store depletion were both reduced by pharmacological inhibition and PKCdelta

207 these assumptions are often violated due to both redundancies in functional descriptions and biologi

208 differentiation, a potential consequence of both regions having served as refugia during glacial adv

209 trials have reported significant benefits in both relapse-free survival (RFS) and overall survival (O

210 strains can cause death in individuals from both risk and non-risk groups, including young adults.

211 such as The Cancer Genome Atlas (TCGA), with both RNA-Seq and array-based platforms available.

212 ressing mice and reduced hyperinsulinemia in both S350L and D734A INSR-expressing animals.

213 te collagen destruction and Hyp release into both saliva and plasma.

214 Higher-order many-body errors are small in both SCAN and self-interaction-corrected SCAN.

215 Both scenarios facilitate range expansion, contraction o

216 e a distinct representational signature from both scene and object views in visual cortex.

217 reptococcus pyogenes Cas9 (SpyCas9), we used both self-targeting CRISPR screening and guilt-by-associ

218 isted of mobile colocation measurements with both sets of the UFP and BC monitors deployed in one of

219 We find that, in NF1 mice of both sexes, inhibition increases strongly during the dev

220 learning in 20 young healthy participants of both sexes.

221 d ommatidia and in vivo from intact flies of both sexes.

222 parity-frailty relationship was similar for both sexes.

223 pigment and pigmented human cartilage tissue both showed hydroquinone-resembling NMR signals.

224 nase, gamma-H2AX spreads as far as ~50 kb on both sides of the lesion within 1 h; but the kinetics an

225 Systems biology analyses highlight both similarities and differences between the mood disor

226 dies revealed maize and mixed-food refuse at both sites, but this study documents actual food consump

227 of these QTL in each environment and across both sites, three main QTL hotspots were found in chromo

228 (SOMO) of this hydrocarbon radical resembles both SOMOs of triangulene, but the spin density is distr

229 In both species, predicted gene targets of differentially e

230 Thus, TH signaling coordinately regulates both spectral sensitivity and sensory plasticity.

231 ith prominent roles in T cell development in both strains.

232 tive double-duty intervention that addresses both stunting and overweight in children aged 4 years an

233 ci of these neural patterns differed between both subjects, suggesting individual variability in the

234 f transpeptidation, and (d) demonstrate that both substrates have to be bound before transpeptidation

235 ltransferases by binding to the same site as both substrates in EmbB and EmbC.

236 osophila pioneer-like factor, functions with both SWI/SNF and ISWI family chromatin remodelers to all

237 lium, using 22,150 urogenital specimens from both symptomatic and asymptomatic men and women collecte

238 In CA1, both synaptic input to single neurons and population act

239 t attack and was observed after injection of both syngeneic and xenogeneic cells.

240 the approach using a birth-death model with both synthetic and experimental data, and show that we c

241 Using both synthetic and experimental datasets for comparison,

242 Both TACTs were well tolerated, although early vomiting

243 Both target-site resistance (TSR) and nontarget-site res

244 nificantly between the treatment groups, and both techniques induced a minimal hyperopic shift.

245 of apoptotic cellular events as evidenced by both terminal deoxynucleotidyl transferase dUTP nick-end

246 production of a range of mini-spidroins with both terminal domains, and characterize their response t

247 in myofibers diminishes, which accounts for both the absolute reliance developing myofibers have on

248 st SMs remains obscure, but understanding of both the activation of silent gene clusters and the ecol

249 l comparisons identify essential elements of both the allosteric ligands and receptor binding sites i

250 It was determined that both the bromine atom and the phosphate group were succe

251 th the chemical composition and structure of both the cell walls and the phytolith structures.

252 However, the optimal models revealed that both the density of eels and the number of other diadrom

253 Both the electronic and steric nature of the sulfonyl mo

254 Lean mass was positively associated with both the energy intake from the ad libitum meal (beta: 1

255 type of ASD with shared dysregulation across both the epigenome and transcriptome.

256 tributions, we show that the H2A.B status of both the father and mother, but not of the zygote, affec

257 r target genes, with a method able to handle both the high number of interacting variables and the no

258 S cm(-1) for a 214 nm thick film, which are both the highest values compared to previously reported

259 indicated that PLA2 required calcium ion for both the hydrolyzing activity and the antioxidant effect

260 feat stress, a mouse model of depression, at both the level of synaptic function and protein expressi

261 al Bayesian models to these data to describe both the mean trip number and duration.

262 Thus, both the molecular function of STEAP1 and its role in ca

263 ng this control is crucial for understanding both the nature of computations needed to successfully t

264 phot2 or chup1 and analyzed the kinetics of both the onset and recovery of NPQ under equivalent inte

265 OFC.SIGNIFICANCE STATEMENT Considering that both the orbitofrontal cortex (OFC) and the opioid syste

266 aks are observed for CA and its fragments in both the positive and negative modes.

267 roach it is necessary to better characterize both the primary metabolism and metabolic regulation of

268 d in real ecological systems and can dictate both the rates of ecological interactions and long-run d

269 ade ago, providing an important resource for both the research and the clinical communities.

270 s set up capable to provide an assessment of both the response reproducibility, by enabling measureme

271 ells in the disease has been demonstrated by both the robust clinical responsiveness of IgG4-RD to B

272 the evolution of 2D TMD research, discussing both the synthetic methods that have enabled the prepara

273 ned this question by separately manipulating both the value-driven and physical salience of targets i

274 nd their potential evolutionary implications-both their opportunities for and potential consequence t

275 and its partner insulin are dually linked in both their secretion from islet cells and their action i

276 apeutics beyond anticoagulants and to target both thrombocytopathy and endotheliopathy.

277 This was superior to both topical mupirocin (1.96-log(10) reduction) and oral

278 Overall, this mechanism allows access to both traditional C-N adducts at room temperature as well

279 s was maintained despite the survivorship in both treatments declining in continued exposure to OA.

280 ovided inferior IPA compared with tirofiban; both treatments yielded greater IPA compared with chewed

281 lar anti-addition mechanisms are postulated, both triggered by HBr, which is evidenced also to take p

282 However, we did identify 2 MZ pairs in which both twins harbored identical rare somatic mutations, su

283 Results show that both unbound linker histones adopt a single compact conf

284 assess the splicing activity of 34 inteins (both uncharacterized and known) using a rapid split fluo

285 tended to be involved in co-infection among both unvaccinated and vaccinated girls.

286 Vaccination with both vaccines prevented fever and protected against abor

287 Rates of both vascular complications and bleeding events decrease

288 eneration of "renovascular units" comprising both vessels and tubules with potential interaction.

289 verlapping ecology, they deviate strongly in both visual and olfactory investment.

290 The reduction in An and gs after anthesis in both water conditions was mainly due a decline in the ch

291 = 3.15; 95% CI: 1.75, 5.67; P-trend <0.001) both were positively associated with risk of diabetes, w

292 hange and provide a framework for predicting both when and where these events may occur.

293 en at day 5 postinfection (d p.i.), although both wild-type and DUBmut virus infections resulted in s

294 ated in coastal lowlands that are exposed to both wind and storm surge hazards.

295 nalyses of cortical thickness were conducted both with and without normalization by ICV.

296 to the working memory subnetwork relates to both working memory and reasoning performance whereas di

297 no significant between-group differences in both worst and average numerical rating scale (NRS) pain

298 duced a similar early metabolic response for both WT-ER and Y537S-ER tumors.

299 itored for 20 of those hives for 6 weeks for both years, during commercial pollination.

300 nce homology but high structural homology to both yeast Get2 and mammalian CAML.