ライフサイエンスコーパス: brain metabolism

1 a show that a calorie-restricted KD enhances brain metabolism.

2 functions, including neural integration and brain metabolism.

3 closely to the magnitude of the reduction in brain metabolism.

4 nts with insomnia is associated with greater brain metabolism.

5 ave long been held to play a special role in brain metabolism.

6 influences on alcohol-associated changes in brain metabolism.

7 cant and should be considered when assessing brain metabolism.

8 ciated with alterations in the regulation of brain metabolism.

9 ing peptide produced at low levels by normal brain metabolism.

10 an anabolic, insulin-like role in developing brain metabolism.

11 due to apoE isoform-specific differences in brain metabolism.

12 brain metabolism found no sex differences in brain metabolism.

13 brain and hippocampal volume in addition to brain metabolism.

14 cin-related changes in WM microstructure and brain metabolism.

15 ow that this metric correlates strongly with brain metabolism.

16 bisphosphate or other sugar bisphosphates in brain metabolism.

17 ranslation of the proposed approach to probe brain metabolism.

18 ut bacteria-derived metabolites in serum and brain metabolism.

19 thways, opening a broad avenue to explore in brain metabolism.

20 l conditions to precisely quantify and model brain metabolism.

21 ated with progressive impairment in PbO2 and brain metabolism.

22 g and may reflect abnormalities in pH and/or brain metabolism.

23 these mRNA levels and both AT expression and brain metabolism.

24 he microvascular network adaptation to local brain metabolism.

25 he interaction between neuronal dynamics and brain metabolism.

26 ood-brain barrier and inadequate glucose for brain metabolism.

27 years and can be associated with changes in brain metabolism.

28 not typically thought to be associated with brain metabolism.

29 of HIV-1 infection and IDU on (18)F-FDG PET brain metabolism.

30 or accurate prediction of regional pediatric brain metabolism.

31 to the relative roles of neurons and glia in brain metabolism.

32 lly guided assessment of relative changes in brain metabolism [4].

33 We studied brain metabolism, a direct index of synaptic function an

34 Brain metabolism across anatomic regions and cellular co

35 lysis, we predict the behavioural diagnosis, brain metabolism and 1-year clinical outcome of individu

36 we demonstrate that the relationship between brain metabolism and aggression is causal, conserved ove

37 edication use and neuroimaging biomarkers of brain metabolism and atrophy as a proxy for understandin

38 The direct correlation between brain metabolism and behavior further suggests that DOCs

39 s a major impact on the relationship between brain metabolism and behavior.

40 nds peak during childhood, and evidence that brain metabolism and body growth rate covary inversely a

41 We performed a cross-sectional study of brain metabolism and cognitive function in 82 healthy ad

42 , allowing a more timely response to adverse brain metabolism and consequently improving patient outc

43 tate characterized by distinctive changes in brain metabolism and cortical function.

44 mprove brain health by restoring homeostatic brain metabolism and CSF dynamics.

45 portant as that of essential amino acids for brain metabolism and development.

46 mplicates global and regional disruptions in brain metabolism and energetics in the pathogenesis of c

47 rch indicates that the relationships between brain metabolism and epileptic seizures are complex and

48 brospinal fluid (CSF) flow adversely affects brain metabolism and fluid balance in the aging populati

49 iomarker panels linked to synaptic function, brain metabolism and glial immunity, and increased brain

50 administration on quantitative indicators of brain metabolism and gliosis.

51 Our results suggest that MB can enhance brain metabolism and hemodynamics, and multimetric neuro

52 vivo approaches to determine how MB affects brain metabolism and hemodynamics.

53 en resting state functional connectivity and brain metabolism and how this results in a distinctive p

54 was associated with less decline in regional brain metabolism and improvement in language abilities,

55 The roles of Cu in brain metabolism and in cell functional speciation and a

56 imaging (MRSI) allows in vivo assessment of brain metabolism and is of special interest in multiple

57 We characterized brain metabolism and microstructure, as measures of brai

58 Sleep deprivation induces changes in brain metabolism and neural activation that involve dist

59 ychological distress promotes alterations in brain metabolism and neurochemistry in wild-type (WT) ra

60 changes in the activity of afferent inputs, brain metabolism and neurotransmitter uptake that are ty

61 racranial pressure, brain electrophysiology, brain metabolism and oxygenation, and cerebral blood flo

62 Also, investigations of the relationship of brain metabolism and specific neurotransmitter systems a

63 Brain metabolism and the activity of the alpha-ketogluta

64 cantly and consistently decreased both whole-brain metabolism and the magnitude.

65 differences in baseline measures of regional brain metabolism and to assess their reproducibility.

66 e extracellular concentration increases with brain metabolism and which, in vitro, inhibits basal for

67 ces existed in the effect of age on regional brain metabolism, and asymmetry of metabolism, in the te

68 stained improvement in arterial ammonia, its brain metabolism, and brain water in cirrhotic rats.

69 highlights the importance of glial cells in brain metabolism, and introduces a systematic and unbias

70 s were associated with decreases in regional brain metabolism, and the correlations were strongest in

71 with lean body mass gain; liver, muscle, and brain metabolism; and bone morphology.

72 of cannabis use whereby global and regional brain metabolism are altered in those with prolonged can

73 Changes in synaptic excitability and reduced brain metabolism are among the earliest detectable alter

74 cur and subsequent developmental declines in brain metabolism are matched by proportionate increases

75 Disorders of brain metabolism are multiform in their mechanisms and m

76 Reference databases of pediatric brain metabolism are uncommon, because local brain metab

77 These findings indicate that brain metabolism as assessed by FDG PET during mental re

78 effects by separated but also differences in brain metabolism as depicted by proton magnetic resonanc

79 Total HDRS score correlates with brain metabolism as measured by fludeoxyglucose F 18 ([(

80 mer's disease, brain amyloid deposition, and brain metabolism as well as progressive cognitive impair

81 was to examine associations between regional brain metabolism, as measured by (18)F-FDG PET, and neur

82 associated with reductions in resting-state brain metabolism, as measured by PET, progressing with d

83 Brain metabolism, as studied by magnetic resonance spect

84 To identify specific regional patterns of brain metabolism associated with abnormal cognitive and

85 s (CVRFs) and subclinical atherosclerosis on brain metabolism at earlier stages remains unexplored.

86 nd immune pathways, in the form of the heart-brain-metabolism axis.

87 -derived (atrophy) or (18)F-FDG PET-derived (brain metabolism) BAG with cognitive performance, neurop

88 flected the consciousness diagnosis based on brain metabolism better than the consciousness diagnosis

89 Brain metabolism between ALS and primary lateral scleros

90 Differences in regional brain metabolism between congenitally helpless and non-h

91 There were no differences in whole brain metabolism between the women and the men.

92 In line with an age-dependent decline in brain metabolism, both ROI and SPM-based methods reveale

93 LC6A8 and their effectiveness in normalizing brain metabolism but also in enhancing our understanding

94 Methylphenidate induced variable changes in brain metabolism, but it consistently increased cerebell

95 his study was to characterize the changes in brain metabolism caused by antecedent recurrent hypoglyc

96 on in arterial ammonia concentration and its brain metabolism, cerebral blood flow, brain cytokine pr

97 t malignant cells integrate into or "hijack" brain metabolism, co-opting neurons and glia for the sup

98 Our data-driven brain metabolism decomposition approach effectively pred

99 pp(NL-G-F) mice exhibited spatial memory and brain metabolism deficits, which were prevented by the h

100 Anesthetic-related manipulation of baseline brain metabolism demonstrates the significant contributi

101 Whole-brain metabolism did not change significantly following

102 Whole-brain metabolism did not differ between on and off condi

103 The adaptive mechanisms that protect brain metabolism during and after hypoxia, for instance,

104 ose as the main energy substrate for resting brain metabolism during intoxication (presumably shiftin

105 brain metabolism are uncommon, because local brain metabolism evolves significantly with age througho

106 etabolite in male rats, the present study of brain metabolism found no sex differences in brain metab

107 ior studies of brain metabolism which viewed brain metabolism from a unitary perspective that equated

108 lation of its overall energy contribution to brain metabolism: glucose (predominantly unlabeled) and

109 ity of anesthetics to change global baseline brain metabolism has created the opportunity to examine

110 of nonalcoholic steatohepatitis (NASH), yet brain metabolism has not been studied in this model.

111 C) paradigm (30-min); and 2) WM and regional brain metabolism imaging metrics, including diffusion te

112 Such reshuffling of brain metabolism implicates key mediation by mitochondri

113 f two sequential doses of methylphenidate on brain metabolism in 15 healthy subjects.

114 y 11 of the 18 patients and led to decreased brain metabolism in a number of cortical areas, with the

115 he interrelationships between microbiota and brain metabolism in childhood undernutrition could provi

116 ell-established cross-sectional biomarker of brain metabolism in dementia with Lewy bodies (DLB), the

117 pathophysiological and therapeutic roles for brain metabolism in epilepsy.

118 s the latest insights into the regulation of brain metabolism in health and disease.

119 The authors measured resting brain metabolism in healthy volunteers with positron emi

120 uld provide objective evidence for disrupted brain metabolism in myalgic encephalomyelitis/chronic fa

121 Abnormalities of brain metabolism in our population of young HIVMSM mainl

122 xyglucose PET to detect abnormal patterns of brain metabolism in patients with neurodegenerative diso

123 adaptive function to transiently upregulate brain metabolism in response to acute energy demand.

124 a marked improvement in behavior and frontal brain metabolism in response to zolpidem.

125 Methylphenidate increased brain metabolism in six subjects, decreased it in two, a

126 er support for the hypothesis of an abnormal brain metabolism in the hippocampal and parahippocampal

127 ter integrity, cerebral blood perfusion, and brain metabolism in the infarcted tissue.

128 Whole brain metabolism in the methamphetamine abusers was 14%

129 yptophan depletion resulted in a decrease in brain metabolism in the middle frontal gyrus (dorsolater

130 in the offspring, but its impact on gut and brain metabolism in the offspring (F1) are unknown.

131 orrelation between clinical motor scores and brain metabolism in the supplementary motor area.

132 However, brain metabolism in these disorders is poorly characteri

133 Decreased brain metabolism in these regions correlated with increa

134 der and also suggest other areas of aberrant brain metabolism in this disorder.

135 mography and fludeoxyglucose F 18 to measure brain metabolism in Vietnam combat veterans with PTSD (n

136 e morphology, and altered liver, muscle, and brain metabolism in ways indicative of a greater ability

137 sed "relative" (region relative to the whole brain) metabolism in the cerebellum and decreased it in

138 llular lactate fractions opens a window into brain metabolism, including in Alzheimer's disease.

139 otid plaque burden is also linked to reduced brain metabolism independently of CVRFs.

140 The alterations in regional brain metabolism induced by the subanesthetic dose may b

141 potential contribution of plasma lactate to brain metabolism is 10% under basal plasma lactate condi

142 Pediatric brain metabolism is a complex function of age and sex.

143 Since brain metabolism is accompanied by heat production, meas

144 Reduced brain metabolism is an invariant feature of Alzheimer Di

145 Altered brain metabolism is associated with progression of Alzhe

146 We suggest that brain metabolism is optimized to minimize the ATP mainte

147 Brain metabolism is thought to be maintained by neuronal

148 An ongoing controversy in brain metabolism is whether increases in neural activity

149 act as a dynamic energy store that supports brain metabolism; its consumption and replenishment is a

150 theory of visual attention, were related to brain metabolism, measured by (18)F-fluorodeoxyglucose p

151 imagery paradigms (26 patients) and resting brain metabolism measurement using (18) fluorodeoxygluco

152 After normalization for whole brain metabolism, methamphetamine abusers exhibited sign

153 e investigated another mechanism critical to brain metabolism, mitochondrial morphology, in BTICs.

154 Outcome measures of brain metabolism, neuroinflammation, and amyloid-beta pa

155 mmation, brain vascular dysfunction, altered brain metabolism, neurotransmitter imbalance and impaire

156 ume is highly heritable early in life, it is brain metabolism-not brain structure-that is the critica

157 though transient, changes in blood flow and brain metabolism occur with IA mannitol infusion.

158 y be associated with modulations in regional brain metabolism occurring remote from the lesion site.

159 ith alcohol use disorder (AUD) show elevated brain metabolism of acetate at the expense of glucose.

160 Previous studies have reported that brain metabolism of acetate is increased more than twofo

161 f so whether this is associated with altered brain metabolism of ammonia or anatomical disturbance of

162 Cellular and brain metabolism of dopamine can be correlated with a nu

163 These data indicate brain metabolism of PCP is significant, but unlike the l

164 These studies examined the microsomal brain metabolism of phencyclidine (PCP) in male and fema

165 Dysfunctional insulin signaling may affect brain metabolism or amyloid deposition.

166 tracers that provide information on regional brain metabolism or blood flow as well as neurochemicall

167 asure of neural activity that is not tied to brain metabolism or hemodynamic responses.

168 tical seizure-associated increases in global brain metabolism, partial brain tissue oxygenation, and

169 Brain metabolism perturbation can contribute to traits a

170 Resting brain metabolism predicted neuronal reactivity and skin

171 l elderly that predicts future cognitive and brain metabolism reductions.

172 n barrier (BBB) and its potential to monitor brain metabolism remained unknown.

173 cits in AD by combining measures of regional brain metabolism (resting state fluorodeoxyglucose posit

174 AT, regional brain metabolism, resting functional magnetic resonance

175 Copper is essential for brain metabolism, serving as a cofactor to superoxide di

176 entire cohort, EEG organization and overall brain metabolism showed no significant association with

177 These turnover rates can provide measures of brain metabolism similar to radioisotope techniques.

178 current hypoglycemia leads to adaptations of brain metabolism so that modest increments in circulatin

179 sought to determine the association between brain metabolism, subclinical atherosclerosis, and CVRFs

180 Methylphenidate induced variable changes in brain metabolism: subjects with the higher D2 measures t

181 et its depletion triggers a reprogramming of brain metabolism sufficient to sustain energy requiremen

182 This pattern of brain metabolism suggests that helplessness vulnerabilit

183 larger proportion of their energy budget on brain metabolism than other primates.

184 ry (TBI) results in persistent disruption of brain metabolism that has yet to be mechanistically defi

185 to identify significant changes in regional brain metabolism that occurred with this intervention.

186 ntify and validate alternative ways to image brain metabolism, through which the efficacy of new ther

187 Change in brain metabolism tracks with blood lactate, suggesting i

188 ed a doubling of the glucose contribution to brain metabolism under hypoglycemic conditions that rest

189 Monitoring of brain metabolism using a cerebral microdialysis continue

190 velop mathematic models of regional relative brain metabolism using pediatric (18)F-FDG PET with CT d

191 ith cognitive symptoms of dementia, regional brain metabolism was a sensitive indicator of AD and of

192 Regional brain metabolism was assessed with (18)F-labeled fluoro-

193 Brain metabolism was compared in patients with (n = 7) a

194 Brain metabolism was evaluated twice during activation (

195 Brain metabolism was first compared between education-ma

196 Brain metabolism was measured with positron emission tom

197 A multivariate analysis of baseline brain metabolism was used to investigate the relationshi

198 In response to potential threat, AT and brain metabolism were assessed in 46 young rhesus monkey

199 of age, optimal models of regional relative brain metabolism were linear for 9 regions, quadratic fo

200 The effects of age on regional relative brain metabolism were modeled using multiple linear and

201 jects, lorazepam-induced decrements in whole brain metabolism were significantly greater in cocaine-a

202 In contrast to prior studies of brain metabolism which viewed brain metabolism from a un

203 ron emission tomography (PET) measurement of brain metabolism with 18fluorodeoxyglucose to show that

204 RI correlate islands of relatively preserved brain metabolism with isolated fragments of behaviour.

205 ssing techniques to measure changes in mouse brain metabolism with preclinical (18)F-FDG PET/CT.