ライフサイエンスコーパス: breakpoint

1 solates with an MIC within 1 dilution of the breakpoint).

2 ticularly for isolates with results near the breakpoint.

3 rtance of reevaluation of the susceptibility breakpoint.

4 inus 1 doubling dilution of the intermediate breakpoint.

5 l turn propensity of the substituents at the breakpoint.

6 uct concentrations remained similar near the breakpoint.

7 equences homologous to those surrounding the breakpoint.

8 , and 16 mE (27.6%) using the 2019 CLSI disk breakpoints.

9 all analyses, with some evidence of multiple breakpoints.

10 Vs per se or adjust the incorrectly assigned breakpoints.

11 rgeted loci and characterized SVs with exact breakpoints.

12 errors (mE) (46.6%) using the 2019 CLSI disk breakpoints.

13 ermined by the weighted average deviation at breakpoints.

14 Clinical and Laboratory Standards Institute breakpoints.

15 obacteriaceae ciprofloxacin and levofloxacin breakpoints.

16 ructures of multiple isoforms with different breakpoints.

17 ce broth microdilution by use of the revised breakpoints.

18 2 structures surrounding and within deletion breakpoints.

19 breakpoints and not susceptible by the 2019 breakpoints.

20 atures of error-prone repair pathways at the breakpoints.

21 using obsolete Enterobacteriaceae carbapenem breakpoints.

22 e been associated with formation of deletion breakpoints.

23 he exception of P. mirabilis, using CLSI/FDA breakpoints.

24 at the laboratory is up to date with current breakpoints.

25 ate homolog affects positioning of crossover breakpoints.

26 Etest and BMD results across CLSI and EUCAST breakpoints.

27 in the same brains and resolve their precise breakpoints.

28 y unrecognized complex rearrangements at the breakpoints.

29 sion transcripts spanning both the 5' and 3' breakpoints.

30 quently maps split reads to identify precise breakpoints.

31 92.3%, and 95.5%, respectively, by the CLSI breakpoints.

32 he latter forming complex tandem duplication breakpoints.

33 d induced structural rearrangements with PSS breakpoints.

34 it more effectively utilized reads spanning breakpoints.

35 egment copy number, and clone specificity of breakpoints.

36 m, called Pegasus, accurately calls deletion breakpoints.

37 breakpoints and 2016 CLSI M100S 26th edition breakpoints.

38 ttee on Antimicrobial Susceptibility Testing breakpoints.

39 are interpreted using CLSI, FDA, and EUCAST breakpoints.

40 d stress the need for P. aeruginosa-specific breakpoints.

41 tigational status has been removed from CLSI breakpoints.

42 th ceftazidime-avibactam MIC values near the breakpoints.

43 g United States Food and Drug Administration breakpoints.

44 pdate process; 16 (47%) successfully updated breakpoints, 12 (35%) received isolates from the CDC in

45 According to CLSI/FDA breakpoints, 13 Enterobacterales isolates (12 clinical a

46 sumed that their instruments applied current breakpoints, 17 (50%) were uncertain how to change break

47 s having early tears if they tore before the breakpoint (38/55 eyes [69%]), and as late tears if they

48 olyticus had unacceptable VMEs with this new breakpoint (6.4%), as did S. hominis (4.0%).

49 Octreotide did not alter the breakpoint among ES or control subjects when tested in a

50 determine why laboratories failed to update breakpoints and (ii) to provide support for breakpoint u

51 comparable to that of BMD using both Vitek 2 breakpoints and 2016 CLSI M100S 26th edition breakpoints

52 ine chromothripsis events involving up to 65 breakpoints and 60.6 Mb across four chromosomes, further

53 em resistance was defined by the most recent breakpoints and applied across the study period.

54 e been shown to frequently harbor additional breakpoints and copy-number imbalances, a complexity pre

55 e phase blocks to determine haplotypes of SV breakpoints and delineate complex breakpoint configurati

56 ntimicrobial Susceptibility Testing (EUCAST) breakpoints and investigational (research-use-only) CLSI

57 ltaneously, preserving uncertainty as to the breakpoints and magnitude of CNVs present in an individu

58 These MICs are susceptible by the 2018 breakpoints and not susceptible by the 2019 breakpoints.

59 ort to summarize filtered fusions, visualize breakpoints and protein domains by transcript, and plot

60 that are significantly affected by recurrent breakpoints and recurrent somatic juxtapositions.

61 BD5-specific signal (PSS) sequences at their breakpoints and recurrently inactivated tumor-suppressor

62 Key management variables such as infection breakpoints and required durations of drug interventions

63 SViCT can detect breakpoints and sequences of various structural variatio

64 The position of the chromosome breakpoints and the mechanisms driving those atypical de

65 vide data to support the reevaluation of CPT breakpoints and to improve agreement across methodologie

66 d amino acid sequences according to multiple breakpoints and transcript isoforms.

67 remove previously established, differing AZI breakpoints and use the ECV as guidance for testing.

68 o kataegis in close proximity to the genomic breakpoints and with the activation of specific signalin

69 producibility of provisional bedaquiline MIC breakpoints and World Health Organization interim critic

70 in turn has led to the creation of clinical breakpoints and, more recently, epidemiological cutoff v

71 ased motivation (decreased progressive ratio breakpoint) and require a longer stimulus length to comp

72 oints, 17 (50%) were uncertain how to change breakpoints, and 10 (29%) lacked resources to perform a

73 ricultural cover associated with DOC and TDN breakpoints, and 15% wetland and 9.5% urban land associa

74 .7%, and 95.5%, respectively, by the Vitek 2 breakpoints, and 93.4%, 92.3%, and 95.5%, respectively,

75 OP2B and XRCC4 are enriched in translocation breakpoints, and map at topologically associating domain

76 to the investigational CLSI, FDA, and EUCAST breakpoints, and results were compared.

77 However, fusions often occur with intergenic breakpoints, and the role of such fusions has not been c

78 Although gene breakpoints, and thus the total number of gene pieces (

79 ymes that remain "carbapenem susceptible" at breakpoint; and (4) Pseudomonas aeruginosa that merely l

80 , we established that avian interchromosomal breakpoints appear in the regions of low density of cons

81 The breakpoint appears to be fairly stable in the future, su

82 These breakpoints are based on pharmacokinetic, pharmacodynami

83 cterales and P. aeruginosa, respectively (no breakpoints are currently available for the A. baumannii

84 While these breakpoints are likely specific to our study area, our s

85 We observed breakpoints are more likely to occur in regions enriched

86 niques, complex rearrangements with multiple breakpoints are often difficult to resolve, and predicti

87 ervations suggest that detected mosaic event breakpoints are preferentially recovered in genomic regi

88 Breakpoints are used to predict whether an antifungal ag

89 clinical outcome data to define clinical Mtb breakpoints, are warranted.

90 -ALL have similar expression profile and IGH breakpoints as Nalm6, suggesting a common mechanism to a

91 However, they decreased motivation in a breakpoint assay and did not promote reversal learning i

92 ple (n = 21,256 total) and were subjected to breakpoint assays for ten antibiotics.

93 or which the presence within 100 kb of an SV breakpoint associates with altered expression.

94 Genome-wide CNV breakpoint association showed not only significant loci

95 align on a hydrological relationship with a breakpoint at 2000 mm annual precipitation, where the sy

96 aled the existence of a single recombination breakpoint at the boundary of the non-structural and the

97 cided to set a susceptible-only interpretive breakpoint at the minimum inhibitory concentration of <=

98 mosomal translocations within Hi-C data with breakpoints at single base-pair resolution.

99 We observed enrichment of evolutionary breakpoints at topologically associating domain boundari

100 ong with strong physical interaction of NAHR breakpoints belonging to the same deletion suggests that

101 We used the genomic breakpoint between BCR and ABL1 genes for the DNA-based

102 Among the diverse location of the breakpoints (BPs) of structural variants (SVs), the brea

103 20 update), EUCAST, and investigational CLSI breakpoints (BPs).

104 Applying EUCAST breakpoints, CA was 94.8% and 95.8% for Enterobacterales

105 Having a breakpoint can improve patient care and surveillance and

106 ated calling are commonly high, and reported breakpoints can be inaccurate.

107 Applying CLSI-FDA breakpoints, categorical agreement (CA) reached 93.0%, 9

108 Here we show that the Rac1 GAP breakpoint cluster region (BCR) associates with NMDA rec

109 topoietic stem cell (HSC) transformed by the breakpoint cluster region (BCR)-abelson (ABL) oncogene a

110 Breakpoint Cluster Region-Abelson kinase (BCR-Abl) is a

111 ical domain borders, and frequently occur at breakpoint clusters commonly translocated in cancer.

112 The breakpoint coincides with a European Committee on AST de

113 octreotide was associated with an increased breakpoint compared with placebo among ES subjects (322

114 have FDA clearance for the revised (current) breakpoints, compounded by the need for laboratories to

115 ypes of SV breakpoints and delineate complex breakpoint configurations at the resolution of single DN

116 The results revealed that most of the breakpoints converged in gp41 (62%) and C1 (25.3%) domai

117 By using chromosome breakpoint data, we established that avian interchromoso

118 Infection with both viruses resulted in breakpoint-dependent expression of EGFP-tk and ganciclov

119 targeted hospitals continued to use obsolete breakpoints despite 1 year of effort.

120 R2 amplified rats' motivation, raising their breakpoint effort price for cocaine by 10-fold.

121 pins were predicted to form near five shared breakpoints, establishing that the initiating event coul

122 ntimicrobial Susceptibility Testing (EUCAST) breakpoints, Etest MEV performance with clinical (16 MEV

123 ses rather than decreases with corresponding breakpoint events.

124 and investigational (research-use-only) CLSI breakpoints exist for interpreting cefiderocol susceptib

125 e over whether the daptomycin susceptibility breakpoint for enterococci (ie, minimum inhibitory conce

126 ed by Gram-negative pathogens, no resistance breakpoint for Escherichia coli exists.

127 ates had MICs </= 16 mg/L (proposed clinical breakpoint for temocillin).

128 ata generated in this study support a single breakpoint for testing trimethoprim-sulfamethoxazole and

129 The segmented regression estimated a breakpoint for the time to tear at 182 days.

130 ndards Institute (CLSI) has set interpretive breakpoints for AZI susceptibility.

131 inolone antimicrobial susceptibility testing breakpoints for both Enterobacteriaceae and Pseudomonas

132 obial Susceptibility Testing established new breakpoints for daptomycin and enterococci.

133 al Laboratory and Standards Institute (CLSI) breakpoints for E. coli were applied for interpretation.

134 y Standards Institute revised the daptomycin breakpoints for Enterococcus spp. twice in rapid success

135 aceae and Pseudomonas aeruginosa, daptomycin breakpoints for Enterococcus spp., and ceftaroline break

136 The breakpoints for PHI and PRHI were 2012.6 (95% confidence

137 boratory Standards Institute (CLSI) M100-S28 breakpoints for S. pseudintermedius/S. schleiferi accura

138 t oxacillin DD tests using the CLSI M100-S28 breakpoints for S. pseudintermedius/S. schleiferi and ox

139 s study led CLSI to adjust the oxacillin MIC breakpoints for SOSA.

140 oints for Enterococcus spp., and ceftaroline breakpoints for Staphylococcus aureus Implementation of

141 hanges to the ciprofloxacin and levofloxacin breakpoints for the Enterobacteriaceae and Pseudomonas a

142 r of these regions show unexpectedly high SV breakpoint frequencies given their predicted susceptibil

143 cer cell fraction of structural variant (SV) breakpoints from whole-genome sequencing data.

144 involving gene transcription and nearby SSV breakpoints, global alterations in DNA methylation in th

145 AR uses an NGS-derived breakpoint graph alongside OM scaffolds to produce high-

146 Current disk diffusion breakpoints (>=21/<=20 mm for susceptible/resistant) pro

147 ith different 5' gene partners and BRAF exon breakpoints have been described, but the effects of diff

148 g-resistant Gram-negative bacteria; however, breakpoints have been established only for Escherichia c

149 iation, the presence of large repeats at the breakpoints hinders the analysis of many structural vari

150 ences of oligonucleotides from a chromosomal breakpoint hotspot in the human c-MYC oncogene containin

151 ng H-DNA-forming sequence from a chromosomal breakpoint hotspot in the human c-MYC oncogene.

152 DNA molecule, and can improve detection and breakpoint identification for structural variants (SVs).

153 clusters of integration sites with multiple breakpoints, implying clonal selection.

154 ear regression crossover model to identify a breakpoint in 13CO2 production (representing the mean re

155 g primers spanning the typical linearization breakpoint in the HBV genome allowed for quantification

156 gate previously reported CNVs, we identified breakpoints in 35 parasite clones with near single base-

157 olution to accurately identify the crossover breakpoints in a typical trio family.

158 Remarkably, BCA breakpoints in eight subjects altered a single TAD encom

159 quences are highly enriched at translocation breakpoints in human cancer genomes, representing an end

160 Both DAAO and IAAO methods provided similar breakpoints in late pregnancy, showing that the DAAO met

161 rs to updating Enterobacteriaceae carbapenem breakpoints in Los Angeles hospitals.

162 estigated the occurrence of nonlinearity and breakpoints in relationships between total dissolved nit

163 mains challenging because many variants have breakpoints in repetitive regions of the genome and thus

164 g in structure variant detection by locating breakpoints in repetitive regions.

165 of the prevalence and location of ecological breakpoints in streams, providing watershed managers pot

166 Our analyses reveal putative breakpoints in the manual reconstruction of the human X

167 02R)) in order to allocate the recombination breakpoints in these immunologically important proteins

168 ltiple genomic read signals for potential SV breakpoints in whole genome sequencing data and proposes

169 rs somatic and germline structural variation breakpoints in whole-genome sequencing data.

170 ere provided to aid laboratories in updating breakpoints, including support from technical representa

171 Microhomology (TAA and AGCT) at the breakpoints indicated that microhomology-mediated FoSTeS

172 Analysis of deletion breakpoints indicates that preferred recombinations occu

173 ROS1 fusion oncogene with identical genomic breakpoints, indicating that the nevi arose from a singl

174 iewer gets the input of fusion gene symbols, breakpoint information, or structural variants from whol

175 TERT-associated breakpoints involve ~3% of cases, most frequently in liv

176 At least 11 validated clustered breakpoints involving intrachromosomal and interchromoso

177 the United States, and an AZI-susceptibility breakpoint is needed.

178 The CLSI breakpoint is now the recognized standard that defines A

179 esence of a somatic structural variant (SSV) breakpoint is recurrently associated with altered expres

180 se of obsolete Enterobacteriaceae carbapenem breakpoints is common in clinical laboratories.

181 that the kataegis observed at chromothriptic breakpoints is the consequence of cytosine deamination b

182 susceptibility testing results using current breakpoints, is crucial for clinical care and infection

183 rks, along with the lack of homology between breakpoint joins and the randomness of the order and ori

184 andem duplications or complex gains, exhibit breakpoint junction features reminiscent of replicative

185 Analysis of the breakpoint junction fragment indicated that these 67 kb

186 eference assembly and the analysis of unique breakpoint junction sequences revealed 63% (57/90) of th

187 PCR) is a traditional approach to obtain CNV breakpoint junction, but this method is inefficient when

188 enous loci followed by the identification of breakpoint junctions within a population, which typicall

189 of 17p11.2, occur up to ~1 Mb away from the breakpoint junctions, and favor C > G transversion subst

190 quency of microhomologies at larger deletion breakpoint junctions, suggesting the involvement of micr

191 nly similar partner genes but also identical breakpoints leading to oncogene overexpression.

192 d Laboratory Standards Institute (CLSI) SOSA breakpoints led to 2.1% very major errors (VMEs) and 7.1

193 A lack of additional organism breakpoints limits clinical use of this agent and has pr

194 es in trends in PHI and PRHI, we used single breakpoint linear segmented regression analysis.

195 s circulating in Hipposideros bats, with the breakpoint located near 5' and 3' ends of the spike (S)

196 t carrying a heterozygous inversion with one breakpoint located within a topologically associating do

197 Seeksv develops a rescue model for SV with breakpoints located in sequence homology regions.

198 airpins within close proximity to all future breakpoint locations.

199 are difficult to characterize because their breakpoints map to large repeats.

200 In four of them, the distal breakpoints mapped within one of the LCR22s and we found

201 The piperacillin/tazobactam non-susceptible breakpoint (MIC > 16 mg/L) best predicted 30-day mortali

202 The SimPlot analysis showed recombination breakpoints near the ORF1/2 junction for all six recombi

203 In many well-known cases, breakpoints occur at two intragenic positions, leading t

204 Standards Institute (CLSI) susceptible-only breakpoint of <=4 mug/mL for daptomycin and enterococci

205 faecium, a susceptible dose-dependent (SDD) breakpoint of <=4 mug/mL was established based on an inc

206 t extinction risk changes around a body mass breakpoint of 0.035 kg, indicating that the lightest and

207 cificity of a bedaquiline MIC susceptibility breakpoint of 0.12 mug/ml for the BMD method and WHO int

208 tion becomes increasingly important when the breakpoint of transmission is approached, and is vital w

209 alis and other enterococcal species, revised breakpoints of <=2 mug/mL-susceptible, 4 mug/mL-intermed

210 The breakpoints of each segment and the gaps in genome cover

211 ints (BPs) of structural variants (SVs), the breakpoints of fusion genes (FGs) are located in the gen

212 ferentially expressed primate genes near the breakpoints of large (>100 kilobases (kb)) inversions bu

213 Long monomeric A/T tracks are found at the breakpoints of many Plasmodium resistance-conferring CNV

214 alysis and genomic sequencing, we mapped the breakpoints of mitotic recombination events and other ch

215 Sequences at the breakpoints of these rearrangements had microhomologies,

216 Specifically, we targeted the breakpoints of TMEM135-CCDC67 and MAN2A1-FER fusions in

217 d, but the effects of different partners and breakpoints on cancer phenotypes and treatment responses

218 CSReport identifies junction segment breakpoints on reference sequences and junction structur

219 d isolates from the CDC in order to validate breakpoints on their systems, and 6 (18%) were planning

220 a validation study for off-label use of the breakpoints on their systems.

221 for complex SVs and SVs that had inaccurate breakpoints or size predictions.

222 In the absence of a specific resistance breakpoint our results suggest a MIC of 32 mg/L to be co

223 parative genomic hybridization (aCGH) and/or breakpoint PCR and 64 were confirmed.

224 SH, 10x Genomics Linked-Read sequencing, and breakpoint PCR sequencing to characterize the structural

225 shape, and a gene adjacent to the inversion breakpoint, PpOFP1, regulates flat shape formation.

226 performed two existing algorithms on precise breakpoint prediction, which is clinically important.

227 better hearing outcomes at 12 months, but VL breakpoints predictive of hearing loss were not identifi

228 This breakpoint presumes that AZI (1-g single dose) is used i

229 fied in new susceptible dose-dependent (SDD) breakpoints promulgated by the Clinical and Laboratory S

230 MEs were acceptable by this new breakpoint, ranging from 0 to 1.2%.

231 rithm, to detect and quantify mtDNA deletion breakpoints rather than mRNA splices.

232 he cat genome, is located in an evolutionary breakpoint region of the giant panda, suggesting that in

233 ative enhancers in the ruminant evolutionary breakpoint regions are highly enriched for DNA sequences

234 genomes, some genes located in evolutionary breakpoint regions are significantly enriched in pathway

235 sion data, we found that genes near ruminant breakpoint regions exhibit more divergent expression pro

236 istent with the phylogenetic origin of these breakpoint regions.

237 s and located near bovidae-to-cattle lineage breakpoint regions.

238 synteny alignments and identify evolutionary breakpoint regions.

239 in BMD and cefoxitin DD tests using the CoNS breakpoints reliably identified mecA-mediated beta-lacta

240 V-diversifies through both recombination and breakpoint repair, while concerted evolution of IR1 is d

241 t reinforcer; the final completed increment (breakpoint) represents reinforcer reward value.

242 sequences in the human reference genome with breakpoint resolution.

243 ng linked-read sequencing, we discover 1,643 breakpoint-resolved unique insertions, in aggregate acco

244 urban land associated with DOC and nutrient breakpoints, respectively.

245 Susceptibility Testing (EUCAST) interpretive breakpoints, respectively.

246 ticolor FISH analysis identified an array of breakpoints responsible for locus- and region-specific t

247 However, the breakpoints responsible for these structural chromosomal

248 bacteriaceae and Pseudomonas aeruginosa This breakpoint revision was deemed necessary on the basis of

249 well as the potential challenges that these breakpoint revisions are likely to pose for clinical lab

250 This minireview describes the breakpoint revisions in the M100 supplement since 2010 a

251 0.5 mug/ml, 4-fold below the susceptibility breakpoint (S </= 2 mug/ml).

252 l seven lines the exact integration site and breakpoint sequences were identified.

253 kase Cas9(D10A) and guide RNAs targeting the breakpoint sequences, and another to deliver an EGFP-HSV

254 approaches (especially ALN-walking) for CNV breakpoint sequencing and highlights their importance in

255 ed nested PCR walking' (ALN-walking) for CNV breakpoint sequencing in 49 subjects with PMD-associated

256 resolved by aCGH, were revealed by efficient breakpoint sequencing.

257 n a proto-HCN background, the replacement of breakpoint serine with a bulky hydrophobic amino acid is

258 FDA or EUCAST breakpoints should be applied to interpret results for E

259 o performs sequence assembly across multiple breakpoints simultaneously, enabling the reconstruction

260 andards Institute (CLSI) has revised several breakpoints since 2010 for bacteria that grow aerobicall

261 pitals were targeted, 7 of which had updated breakpoints since the prior survey.

262 ignatures presented by variants containing 3 breakpoints, such as those generated by various copy-pas

263 is encountered with increasing frequency: a breakpoint supported by pharmacokinetic/pharmacodynamic

264 BreakPoint Surveyor (BPS) is a computational pipeline fo

265 or two-bottle-choice test, progressive ratio breakpoint test, immunohistochemistry, RNAscope, quantit

266 sed the ceftazidime-avibactam disk diffusion breakpoints that provide the lowest discrepancy error ra

267 s interpreted using S. aureus/S. lugdunensis breakpoints, the CA was 97.6% and 96.2%, respectively.

268 egions in the proximity of sequence assembly breakpoints, the majority of which contained complex arr

269 on to developing and updating susceptibility breakpoints, the SC develops and validates new testing m

270 For any combination of gene pairs/breakpoints to be involved in fusion genes, the users ca

271 les, with the potential to define chromosome breakpoints to bp resolution.

272 in addition to the inability of the previous breakpoints to detect low-level resistance to this antib

273 Adjusting this breakpoint up by a dilution (susceptible, <=0.5 mug/ml;

274 All hospitals launched a breakpoint update process; 16 (47%) successfully updated

275 breakpoints and (ii) to provide support for breakpoint updates.

276 We calculated breakpoints using piecewise regression, two dimensional

277 The mean drug breakpoint value was also significantly lower in the act

278 ygen; and the change in QY at the Kok effect breakpoint was unaffected by oxygen.

279 a, independent replicates and both inversion breakpoints, we demonstrate that the technique is highly

280 The recombination breakpoints were detected at positions varying from nucl

281 tted using a LOWESS smoother, and structural breakpoints were determined by Chow test.

282 Genes disrupted by SV breakpoints were enriched in neuronal lineages and assoc

283 ulase-negative Staphylococcus species (CoNS) breakpoints were highly reliable for detecting mecA-medi

284 Viral DNA breakpoints were nonrandom and tended to assemble in lar

285 Breakpoints were related to land use gradients, with 34-

286 ynamic analyses suggesting that the previous breakpoints were too high, in addition to the inability

287 Nonlinear relationships can contain breakpoints where there is an unexpected change in an ec

288 of mean values of two adjacent segments at a breakpoint, where the significant degree of change-point

289 e promoter is often increased with nearby SV breakpoint, which may involve inactivation of repressor

290 dentified novel haplotypes and recombination breakpoints, which could be exploited for further improv

291 ents identified random patterns of clustered breakpoints with copy-number alterations resulting in in

292 med best when interpreted with the CLSI SOSA breakpoint, with 1.0% VMEs and 2.9% MEs.

293 s were interpreted according to CLSI E. coli breakpoints, with 49.0 to 85.8% considered susceptible,

294 entified 861 genes mapping at 156 inversions breakpoints, with some showing evidence of differential

295 er enhancer located distally to the deletion breakpoints, with subsequent allele-specific upregulatio

296 ions are observed with at least one deletion breakpoint within unique sequence between the LCR22s.

297 All RP17 SVs had breakpoints within a genomic region spanning YPEL2 to LI

298 lyzed, identifying depletions of gene fusion breakpoints within coding regions of fused genes as well

299 genes as well as an N-terminal enrichment of breakpoints within fused genes.

300 with BRCT domain mutations harbor BRCA1 gene breakpoints within or adjacent to Alu elements in intron

301 Oxacillin BMD using S. aureus/S. lugdunensis breakpoints yielded the highest VMEs at 17.4% and 90% CA