ライフサイエンスコーパス: bristle

1 the caterpillar, namely the tegument and the bristle.

2 lusters of cells at the sites of each future bristle.

3 ses N phenotypes in the adult mechanosensory bristle.

4 of a pupal-like abdomen with few or no short bristles.

5 repattern that allows precise positioning of bristles.

6 also rescuing dPsn-induced malformations in bristles.

7 ized cuticular structures, such as hairs and bristles.

8 ptors in hair cells as well as in Drosophila bristles.

9 ement in shaping mosquito scales compared to bristles.

10 veins, increased bristle density, and tufted bristles.

11 of achaete allows formation of the remaining bristles.

12 described; it causes a loss of some sensory bristles.

13 te expression that results in the additional bristles.

14 variation in the number of ventral abdominal bristles.

15 ocation of the longitudinal actin bundles in bristles.

16 filaments are prominent features of growing bristles.

17 ty to induce the formation of mechanosensory bristles.

18 gth of the scutum, through secondary loss of bristles.

19 of the rows of acrostichal and dorsocentral bristles.

20 hereas its overexpression results in loss of bristles.

21 rotation is blocked by a neighboring row of bristles.

22 tial for Dyl plasma membrane localization in bristles.

23 for male-specific morphogenesis of sex comb bristles.

24 for the morphogenesis of both denticles and bristles.

25 yl is also required for cuticle formation in bristles.

26 morphological structure composed of modified bristles.

27 velopment, poor fertility, and short slender bristles.

28 For the apical bristle, a precursor is singled out and undergoes a firs

29 Our experiments suggest that recurved bristles allow the fly to sense the presence of objects

30 Thus, bristle and hair cells use microvilli and cross-bridges

31 g adult development of Drosophila suppressed bristle and hair formation when induced early or redirec

32 markers in 20E-free cultures showed that the bristle and joint cells had not undergone any further mo

33 and prickle, function to regulate wing hair, bristle and ommatidial polarity.

34 log Rheb each resulted in duplication of the bristle and socket cells, progeny of the pIIa cell, and

35 that profilin promotes actin assembly in the bristle and that a balance between capping protein and p

36 to further define Ubx function in patterning bristle and trichome patterns in the legs.

37 mation of branched arista laterals, branched bristles and a strong multiple hair cell phenotype that

38 ignaling controls the orientation of sensory bristles and cellular hairs (trichomes) along the antero

39 cause the classic Minute phenotypes of small bristles and delayed development.

40 ther feather types such as contour feathers, bristles and down feathers.

41 to be the main contributor while both nylon bristles and elastomers could act as absorptive sinks fo

42 ore, that Ed is required to suppress sensory bristles and for proper wing vein specification during a

43 tity of the major actin-bundling proteins in bristles and hairs are known, this information on scales

44 croscopy shows that escapers have defects in bristles and hairs, indicating that this motor protein p

45 present around the periphery of other insect bristles and hairs, longitudinal ridges in lepidopteran

46 The pattern of bristles and intervening epithelial cells (ECs) becomes

47 ve opposite effects on the number of sensory bristles and on wing venation phenotypes induced by modi

48 and nonvolatile pheromones through gustatory bristles and pegs distributed on multiple body parts inc

49 esults in an increased production of sensory bristles and sensory organ precursor (SOP) cells on the

50 entation and the number of ventral abdominal bristles and sex comb teeth) in a natural population of

51 odule coordinates polarity among and between bristles and surrounding cells to direct this rotation.

52 oduce epidermal hairs, the shafts of sensory bristles and the lateral extensions of the arista are at

53 terminate in either a spikelet or a sterile bristle, and these structures appear to be paired.

54 Joints, bristles, and claws were dependent on 20E for differenti

55 tion of chitin, a major cuticle component in bristles, and disrupting Rab11 function leads to phenoty

56 s governing the parallel alignment of hairs, bristles, and ommatidia in Drosophila have all served as

57 r than 400 ng 20 E/ml) than pretarsal claws, bristles, and other joints (greater than 40 ng 20E/ml).

58 ncluding dark deposits on the eye, truncated bristles, and semilethality.

59 er adult leg, the six distalmost joints, the bristles, and the pretarsal claws, were examined to inve

60 nchung-expressing neuron under each recurved bristle are essential for its mechanosensitivity and the

61 , our results reveal that although scale and bristle are thought to be homologous structures, actin b

62 arized outgrowths including epidermal hairs, bristles, arista laterals, and dendrites.

63 Macrochaetes, large sensory bristles arranged into species-specific stereotypical pa

64 Su(Raf) Hsp83 mutants can extend to thoracic bristles as well as previously reported effects on viabi

65 us and ectopic Ubx expression are limited to bristles at specific locations.

66 However, the mechanosensory bristles at the Drosophila wing margin have been reporte

67 curvature is planar and far greater near the bristle base.

68 rneal epithelium was removed with a rotating bristle brush and stromal thickness monitored for 1 hour

69 ments to further mitigate biofouling such as bristle brushes and UV lamps.

70 ved in lateral inhibition of interommatidial bristles but is not required for induction of the cone c

71 mir-9a induces a subtle increase in sensory bristles, but a substantial loss of wing tissue.

72 Large bristles called macrochaetes are arranged into species-s

73 The nanotube bristles can also be chemically functionalized for selec

74 In contrast, the long bristle cell extension is supported by equally long (up

75 thway inhibitor, and H heterozygotes exhibit bristle cell fate phenotypes reflecting gain-of-Notch si

76 effector for mediating the attachment of the bristle cell membrane to chitin to establish a stable cu

77 the reader, into applying your skills to the bristle cell.

78 Drosophila bristle cells are shaped during growth by longitudinal b

79 on, loss of lilli in adult photoreceptor and bristle cells results in a significant decrease in cell

80 In other species, bristle cells that make up the sex combs arise in their

81 oneural activity that can rescue the loss of bristles characteristic of wg mutants.

82 unction leads to phenotypes that result from bristle collapse rather than a failure to elongate.

83 ayer that encloses the pupa) leading to less bristle curvature along the shaft.

84 Thus, the pattern of bristle curvature is a product of both extrinsic factors

85 We have identified an essential role for the bristle cuticle in the maintenance of bristle structure

86 in addition to senseless, contributes to the bristle defects of the mir-9a mutant.

87 that give rise to Drosophila mechanosensory bristles, Delta (Dl) ligand in the sensory organ precurs

88 wing margin, thickened wing veins, increased bristle density, and tufted bristles.

89 tly evolved, male-specific array of modified bristles derived from transverse bristle rows found on t

90 The effects of Ubx on bristle development are highly dependent on the context

91 bchs function restores viability and normal bristle development in animals with reduced rab11 functi

92 lates the assembly of actin filaments during bristle development in Drosophila and filopodia formatio

93 ases Ubx function is required shortly before bristle development is blocked.

94 Drosophila melanogaster bristle development is dependent on actin assembly, and

95 QTL mapped to the same location as candidate bristle development loci, several QTL regions did not en

96 Suppression of bristle development or changes in bristle morphology in

97 sophila melanogaster wing vein and scutellar bristle development to screen Rab proteins predicted to

98 ntennal growth, joint formation, and sensory bristle development).

99 s in metamorphosis including leg elongation, bristle development, and pigmentation.

100 Here, we describe a new gene involved in bristle development, identified through the use of natur

101 During Drosophila sensory bristle development, precursor cells segregate Numb asym

102 x act antagonistically to one another during bristle development.

103 ristle structure and shape at late stages of bristle development.

104 For the posterior sternopleural bristle, development on T3 ceases after proneural cluste

105 Drosophila bristles display a precise orientation and curvature.

106 ty and patterning defects in eye and sensory bristles due to cis-regulatory lesions in the cell cycle

107 wings with ectopic sensilla and chemosensory bristle duplications.

108 The actin bundles essential for Drosophila bristle elongation are hundreds of microns long and comp

109 ng bristle rudiment to provide direction for bristle elongation, a process thought to be orchestrated

110 actin bundles and Ae-Forked are required for bristle elongation, but not for that of scales.

111 actin bundle structure and found that during bristle elongation, snarls of uncross-linked actin filam

112 en its function is reduced in the Drosophila bristle, F-actin levels increase and the actin cytoskele

113 e genes (amos and ato) must suppress sensory bristle fate as well as promote alternative sense organ

114 Surface appendages such as bristles, feathers and hairs exhibit both long- and shor

115 s the ability of ectopic wingless to inhibit bristle formation and furrow progression.

116 al gene expression (and thus interommatidial bristle formation) and positions the morphogenetic furro

117 ughterless to promote furrow progression and bristle formation, respectively, can block ectopic wingl

118 compartment boundaries - in consequence, the bristles from each segment send their nerves to the CNS

119 nal, conductive brushes with carbon nanotube bristles grafted on fibre handles, and demonstrate their

120 caused by loss of Jagunal affects oocyte and bristle growth.

121 that actin bundles are required for shaping bristle, hair, and scale morphology.

122 al cells contain cellular extensions such as bristles, hairs, and scales.

123 rding to the head size (normal or short) and bristle hardness (medium or soft) of the TB used.

124 The performance of these bristles has been limited by the oxidation and degradati

125 ting-rotating powered toothbrush with a soft-bristle head resulted in higher GM stability after root

126 ormones brassinosteroids (BRs) in specifying bristle identity and maintaining spikelet meristem deter

127 -of-function bsl1 mutants fail to initiate a bristle identity program, resulting in homeotic conversi

128 unction is the appearance of ectopic sensory bristles in addition to loss of olfactory sensilla, owin

129 yet to be properly examined: tactile facial bristles in birds.

130 ss to specify the precursors of most sensory bristles in Drosophila.

131 iated with an increase of 0.35 sternopleural bristles in laboratory strains in two large samples of w

132 neurons of about 20 male-specific gustatory bristles in the forelegs.

133 e of 300+ species that share the presence of bristles in the inflorescence.

134 As is the case in bristles, in hairs dyl mutants display a dramatic phenot

135 Typical materials for constructing brush bristles include animal hairs, synthetic polymer fibres

136 ion of R8 photoreceptors and interommatidial bristles (IOBs).

137 Because the bristle is curved, the actin bundles on the superior sid

138 The morphogenesis of Drosophila sensory bristles is dependent on the function of their actin and

139 In the leg, a group of small mechanosensory bristles is organized into a series of longitudinal rows

140 e elongating cell membrane, giving the adult bristle its characteristic grooved pattern.

141 w a specific defect (supernumerary scutellar bristles) known to be caused by Hh overexpression.

142 the normal morphogenesis of epidermal hairs, bristles, laterals, and dendrites.

143 rs) for the tegument library and 368 for the bristle library.

144 The hair of FAHN/SPG35 patients shows a bristle-like appearance; scanning electron microscopy of

145 Awns, bristle-like structures extending from grass lemmas, pro

146 scription in the pIIa and pIIIb cells of the bristle lineage.

147 differentiation of post-mitotic cells in the bristle lineage.

148 In the Drosophila melanogaster sensory bristle lineages, Numb inhibits the recycling of Notch a

149 For example, taste bristles located in the male forelegs and the labial pal

150 nd ventral cibarial organs, as well as taste bristles located on the wings and tarsi.

151 (Mex67p) as the protein encoded by the small bristles locus.

152 >90% power to detect effects as low as 0.27 bristles (<1% of the total variation in bristle number)

153 length ~200 microm) are homologous to insect bristles (macrochaetes), and their colors create the pat

154 llectively formed brush-like structures with bristles made of bundles of 2-27 nups, however, the bund

155 Soft-bristle manual and powered toothbrushes were given to pa

156 rican Dental Association (ADA)-accepted soft-bristle manual brush in a non-flossing gingivitis popula

157 1 ion channel has a role in both hearing and bristle mechanosensation in fruit flies and in proprioce

158 tion of actin bundles located throughout the bristle membrane to an asymmetrical organization.

159 primordia of a group of small mechanosensory bristles (microchaetae), which on the legs of the Drosop

160 rthermore, overexpression of profilin in the bristle mimics many features of the cpb loss-of-function

161 r, expression of the CAPZA2 variants affects bristle morphogenesis, a process that requires extensive

162 able data set for future studies on hair and bristle morphogenesis, cuticle synthesis, and planar pol

163 am of cut and tramtrack to implement correct bristle morphogenesis.

164 bft locus is required for (interommatidial) bristle morphogenesis.

165 kle protein determines right- or left-handed bristle morphogenesis.

166 ression of bristle development or changes in bristle morphology in response to endogenous and ectopic

167 result in female sterility, aberrant sensory bristle morphology, loss or degeneration of tissues, and

168 leton becomes disorganized, causing abnormal bristle morphology.

169 Unlike other ectopic bristle mutants, Tufted is epistatic to achaete and scut

170 to transient activation of mechanosensitive bristle neurons and sweet-sensing chemoreceptor neurons.

171 beams independently activate mechanosensory bristle neurons on different body parts.

172 ould detect dust, we focus on mechanosensory bristle neurons, whose optogenetic activation induces a

173 led make the epidermal cells inhospitable to bristle neurons; sensory axons that are too near these c

174 for high or low, sternopleural or abdominal bristle number and an isogenic wild-type chromosome.

175 visible in the adult fly: increased sensory bristle number and the formation of a rough eye produced

176 cted genotype/phenotype associations between bristle number and variants in the introns of Delta cann

177 ncing selection or assume variants affecting bristle number are neutral, than mutation-selection equi

178 icantly associated with natural variation in bristle number as assessed by a permutation test.

179 we show that divergence in clasper size and bristle number between Drosophila mauritiana and Drosoph

180 uantitative effects of P elements on sensory bristle number can identify genes affecting neural devel

181 n interval that does not include any classic bristle number candidate genes.

182 cting Drosophila abdominal and sternopleural bristle number have occurred in 11 replicate lines durin

183 variation in sternopleural and/or abdominal bristle number in Drosophila melanogaster, for both a la

184 ariation in male abdominal and sternopleural bristle number in nature.

185 ait loci (QTL) for Drosophila mechanosensory bristle number in six recombinant isogenic line (RIL) ma

186 n polymorphisms associated with variation in bristle number is more parsimoniously explained by model

187 ween spontaneous mutations and QTL affecting bristle number on the deficiency-bearing chromosomes, wh

188 e complex (ASC) polymorphisms and Drosophila bristle number phenotypes in several new population samp

189 We confirm previous observations of bristle number QTL distal to 4A at the tip of the chromo

190 ophila and test the influence of E(spl)-C on bristle number variation in a natural cohort.

191 ly shown to be associated with sternopleural bristle number variation in both sexes in a set of isoge

192 r harboring alleles having subtle effects on bristle number variation.

193 QTL for bristle number were mapped separately for each chromosom

194 Five X-linked QTL influencing bristle number were resolved to intervals of approximate

195 0.27 bristles (<1% of the total variation in bristle number) we did not replicate the association in

196 detected, of which 33 affected sternopleural bristle number, 31 affected abdominal bristle number, an

197 leural bristle number, 31 affected abdominal bristle number, and 11 affected both traits.

198 as little as 2% of segregating variation for bristle number, and saturating the region with single-nu

199 ments as a class contributes to variation in bristle number, apparently in a sex- or trait-limited fa

200 he proneural cluster increases adult sensory bristle number, whereas its overexpression results in lo

201 s influenced the normally invariant thoracic bristle number, while none affected invariant scutellar

202 n longevity, locomotor behavior, and sensory bristle number.

203 ber, while none affected invariant scutellar bristle number.

204 dence for epistasis between loci for clasper bristle number.

205 body weight, and abdominal and sternopleural bristle numbers) were measured in outbred heterozygous F

206 uronal cells associated with diverse sensory bristles of both the chemo- and mechanosensory systems.

207 rmation of a majority of the interommatidial bristles of the eye and cause defects in other external

208 ng terminal organ and in adults on the taste bristles of the labelum, the legs, and the wing margins.

209 complementation groups: broad (br), reduced bristles on palpus (rbp), and 2Bc.

210 Ubx blocks the development of two particular bristles on T3 at different points in sensory organ deve

211 major gustatory organs, including the taste bristles on the anterior wing margin.

212 by a large number of ectopic mechanosensory bristles on the dorsal mesothorax.

213 d a previously unknown function for recurved bristles on the Drosophila melanogaster wing.

214 The organization of bristles on the Drosophila notum has long served as a po

215 phila the stereotyped arrangement of sensory bristles on the notum is determined by the tightly regul

216 the wing, ommatidia in the eye, and sensory bristles on the notum.

217 ra vicina displays a pattern of four rows of bristles on the scutum resembling the postulated ancestr

218 omote the development and migration of other bristles on the third femur and to repress trichomes.

219 The distribution of sensory bristles on the thorax of Diptera (true flies) provides

220 The stereotyped, two-dimensional pattern of bristles on the thorax of Drosophila has been intensivel

221 The polarity of sensory bristles on the thorax of Drosophila is linked to the or

222 xifen (a JHM) had little effect on abdominal bristle or cuticle formation, but disrupted the developm

223 The sex comb is an array of modified bristles or 'teeth' present on the male forelegs of seve

224 Bristle pattern in the first leg also differs between ma

225 The thoracic bristle pattern of Drosophila results from the spatially

226 a variety of functional elements controlling bristle patterning and on the basis of prior work is a s

227 enotype strongly resembles the wing-hair and bristle patterning defects observed in Drosophila frizzl

228 uggest that interactions between Ubx and the bristle patterning hierarchy have evolved independently

229 Here, we use bristle patterning in the fly notum as a model system to

230 e their fate, ensuring efficient and orderly bristle patterning.

231 To investigate evolutionary changes in bristle patterns and ac-sc regulation by pnr, we have is

232 Other species of flies have different bristle patterns and so comparisons between them provide

233 Stereotyped bristle patterns are common among species of acalyptrate

234 ply innovative analysis to an old problem of bristle patterns in Drosophila, reducing the nonlinear i

235 x) controls specific differences between the bristle patterns of the second and third thoracic segmen

236 joints connecting the legs to the thorax, in bristle patterns, and in the positioning of some sensory

237 s in Drosophila have clearly distinguishable bristle patterns.

238 role in specifying segment- and sex-specific bristle patterns.

239 era, allowing the development of stereotyped bristle patterns.

240 t artificial selection changes the number of bristles per comb without a proportional change in the s

241 chickadee mutations suppress the abnormal bristle phenotype and associated abnormalities of the ac

242 nt suppressor of the ectopic interommatidial bristle phenotype.

243 of the bft gene is the cause of the observed bristle phenotype.

244 gulatory elements, allows the development of bristles positioned at wild-type locations.

245 op through either sex-specific patterning of bristle precursor cells or male-specific morphogenesis o

246 by transcriptional activation at sites where bristle precursors develop and by repression outside of

247 an essential function for the segregation of bristle precursors.

248 and skin mechanoreceptors in vertebrates, to bristle receptors in flies and touch receptors in worms,

249 Loss of yellow expression in these modified bristles reduces their melanization, which changes their

250 ated that the mechanosensitivity of recurved bristles requires Nanchung and Nanchung-expressing neuro

251 Poor actin cross-bridging in mutant bristles results in altered curvature.

252 pression are sufficient to repress an eighth bristle row on the posterior second and third femurs, wh

253 of modified bristles derived from transverse bristle rows found on the first thoracic legs in both se

254 combs originate as one or several transverse bristle rows that subsequently rotate 90 degrees and ali

255 defines the positions of the mechanosensory bristle rows.

256 the socket cell overlies the newly emerging bristle rudiment to provide direction for bristle elonga

257 We found that mutations in small bristles (sbr) affect several tissues during the develop

258 s phenotypically resemble mutations in small bristles (sbr), the Drosophila homolog of the human mRNA

259 By using a conditional mutation in small bristles (sbr), which encodes an mRNA nuclear export fac

260 f external sensory organs, which secrete the bristle shaft and socket.

261 el actin bundles in nurse cell cytoplasm and bristle shaft cells.

262 process and that Rab11 trafficking along the bristle shaft is mediated by microtubules.

263 Actin filaments are important for bristle shape and elongation, while microtubules are tho

264 fabricated SH surfaces had the appearance of bristled shark skin and were robust with respect to mech

265 electron microscopic analysis of individual bristles showed that curvature is planar and far greater

266 Examination of bundle disassembly in mutant bristles shows that plasma membrane association and cros

267 of Delta-Notch signaling cannot account for bristle spacing or the gradual refinement of this patter

268 system development, as well as adult sensory bristle specification and shows that Ed interacts synerg

269 nch number and density, spikelet number, and bristle (sterile branchlet) number; these differences al

270 or the bristle cuticle in the maintenance of bristle structure and shape at late stages of bristle de

271 of the most abundant proteins present in the bristle, tegument, hemolymph, and "cryosecretion".

272 uritiana specifies larger claspers with more bristles than the allele of D. simulans Therefore, we ha

273 nchung-expressing neuron under each recurved bristle that forms an array along the wing margin as bei

274 The cuticular hairs and sensory bristles that decorate the adult Drosophila epidermis an

275 phila adult abdomen bears oriented hairs and bristles that indicate the planar polarity of the epider

276 cells survive loss of borr and develop giant bristles that may reflect their high degree of ploidy.

277 t of the cuticle is decorated with hairs and bristles that point posteriorly, indicating the planar p

278 yed during the development of all Drosophila bristles, they play fundamentally different roles in dif

279 that the inner pupal case induces elongating bristles to bend when they contact this barrier.

280 program, resulting in homeotic conversion of bristles to spikelets.

281 dures compared with the use of a manual soft-bristled toothbrush.

282 that >2% of the genome could affect just one bristle trait and that there must be extensive pleiotrop

283 ions lead to more severe effects on variable bristle trait means than do single Hsp83 mutations.

284 mplementary effects on thoracic and variable bristle trait numbers, depending on the allelic combinat

285 the phenotypic or environmental variance of bristle traits and that complementation of E(sev) and Su

286 ith diploid per-character mutation rates for bristle traits of 0.03.

287 ev) alleles consistently influenced variable bristle traits while there were fewer effects of the Su(

288 variance, or developmental stability of the bristle traits.

289 enotypic variances of invariant and variable bristle traits.

290 ication of the correct identity of external (bristle-type) sensory organs in Drosophila.

291 PD axis, such as the positioning of specific bristle types and leg joints.

292 osophila anterior wing margin mechanosensory bristles undergo PCP-directed apical rotation, inducing

293 we studied the sex comb, a group of modified bristles used in courtship that shows marked morphologic

294 involves only the modification of individual bristles, while other species have more complex "rotated

295 s adults, sbr flies have smaller and thinner bristles with a reduced diameter, suggesting a defective

296 men of adult Drosophila bears mechanosensory bristles with axons that connect directly to the CNS, ea

297 chnin A (1) is an antifungal polyketide that bristles with ethyl groups mounted onto a caged heterotr

298 es can be stabilized by culturing elongating bristles with jasplakinolide, a membrane-permeant inhibi

299 Here we describe a new fossil polychaete (bristle worm) from the early Cambrian Canglangpu formati

300 reproduce in an all-or-nothing mode, such as bristle worms: females committed to reproduction spend r