ライフサイエンスコーパス: broad spectrum

1 for inappropriate use included unnecessarily broad spectrum (29%), no infection or nonbacterial syndr

2 iable, narrow-spectrum inhibitors, while the broad-spectrum AcrIIA1 stimulates Cas9 degradation for p

3 NCI-5-dose screening revealed broad-spectrum activities (GI(50): 1.43-2.09 muM) and 17

4 fluoroacetate activating group and exhibits broad spectrum activity against class A, C, and D serine

5 Some derivatives displayed broad spectrum activity, encompassing Escherichia coli,

6 l polymerase activity that possesses unusual broad-spectrum activity against diverse paramyxoviruses

7 lectin, H84T banana lectin (H84T), to retain broad-spectrum activity against multiple influenza strai

8 haride binding lectin that has shown in vivo broad-spectrum activity against viruses, including sever

9 AMPs have been classically assumed to have broad-spectrum activity and simple kinetics, but recent

10 uare-planar gold(I) complexes with excellent broad-spectrum activity display potent antifungal effect

11 to overcome tetracycline resistance and has broad-spectrum activity that includes gram-positive bact

12 results suggest orlistat has potential as a broad-spectrum agent against multiple mosquito transmitt

13 e antibiotics have found enormous success as broad spectrum agents that exert their activity through

14 antibiotic prescription rates, especially of broad-spectrum agents, have decreased in recent years.

15 ly conserved, limiting the identification of broad-spectrum agents.

16 resistance patterns and avoid the overuse of broad-spectrum agents.

17 AIV outbreaks, and design more efficient and broad-spectrum agricultural and human prepandemic vaccin

18 s proof of the feasibility of a well-behaved broad-spectrum allosteric antiviral and describes a chem

19 sulfide stress and sheds light on a role for broad-spectrum amino acid exporters.

20 Gentamicin is a potent broad-spectrum aminoglycoside antibiotic whose use is ha

21 Our results indicate that AM1710 is not a broad-spectrum analgesic agent in mice and suggest the n

22 elopment and in vivo validation testing of a broad-spectrum and high-absorbance near-infrared optoaco

23 anged from 0.8 to 1.4, and the ratio between broad-spectrum and narrow-spectrum prescriptions ranged

24 -based compounds as antivirals that are both broad-spectrum and selective in nature.

25 hod relies on measurements of the width of a broad spectrum, and does not require any information abo

26 wledge and demonstrate that the FDA-approved broad-spectrum anti-infective drug nitazoxanide (NTZ) bl

27 Glucocorticoids are powerful, broad-spectrum anti-inflammatory agents, but their use i

28 aliphatic heterocycle provide a new class of broad-spectrum antibacterial agents with activity agains

29 nitially identified in pig leukocytes with a broad-spectrum antibacterial and antiviral activity, and

30 Secondary analysis demonstrated wide use of broad-spectrum antibacterials, despite a paucity of evid

31 sed by the gut microbiota, as confirmed by a broad-spectrum antibiotic model.

32 %-41.6%), and among those prescriptions, the broad-spectrum antibiotic prescription rate was 52.1% (r

33 Ciprofloxacin is a broad-spectrum antibiotic that is recognized as one of t

34 mindful of the potential risks of long-term broad-spectrum antibiotic therapy.

35 Furthermore, while broad-spectrum antibiotic treatment (to deplete the inte

36 ding of the detrimental effects conferred by broad-spectrum antibiotic use on the health of the benef

37 Broad-spectrum antibiotic use was reported.

38 LRIs and might contribute to a reduction in broad-spectrum antibiotic use.

39 Compared to the baseline period, broad-spectrum antibiotic utilization decreased by 24.4%

40 a(-/-)PI2(-/-) NOD mice with enrofloxacin, a broad-spectrum antibiotic.

41 We conclude that prolonged exposure to broad spectrum antibiotics in the neonatal period is ass

42 ing the microbial burden in mutant mice with broad spectrum antibiotics-as well as transplanting gut

43 econd or third-generation cephalosporin, and broad-spectrum antibiotics (Broad-abx).

44 allergies (BLAs) are more likely to receive broad-spectrum antibiotics and experience adverse outcom

45 ID) physicians remotely reviewed patients on broad-spectrum antibiotics and those admitted with lower

46 We show that patients exposed to broad-spectrum antibiotics during previous hospitalizati

47 of antibiotics are rare, structurally novel broad-spectrum antibiotics exceptionally so.

48 C57BL/6 male mice were treated with broad-spectrum antibiotics for 4 weeks to deplete their

49 Neonatal mice were transiently exposed to broad-spectrum antibiotics from birth for either 3- (SE)

50 ystem exploits the toxicity of commonly used broad-spectrum antibiotics geneticin and puromycin to ki

51 dies on vaccination in subjects treated with broad-spectrum antibiotics have provided causal evidence

52 3rd generation cephalosporins (1st-3rdCE) to broad-spectrum antibiotics in decreasing surgical site i

53 pean EDs in prescriptions of antibiotics and broad-spectrum antibiotics in febrile children.

54 hus, MscL activators have potential as novel broad-spectrum antibiotics or adjuvants that work with a

55 Treatment with broad-spectrum antibiotics substantially reduced colonic

56 ift the strategy for UTI treatment away from broad-spectrum antibiotics targeting conserved aspects o

57 Here, we administered broad-spectrum antibiotics to healthy adults prior and s

58 Broad-spectrum antibiotics were not effective.

59 a new chemical scaffold for developing novel broad-spectrum antibiotics which can help replenish the

60 Aminoglycosides are broad-spectrum antibiotics whose mechanism of action is

61 Of patients initially treated with broad-spectrum antibiotics, most were still receiving br

62 hydroxychloroquine, lopinavir/ritonavir, and broad-spectrum antibiotics, she ultimately died from mul

63 es, cancer, use of antibiotics, particularly broad-spectrum antibiotics, were associated with prolong

64 The development of novel broad-spectrum antibiotics, with efficacy against both g

65 se with high BSI risk (> 40%) be admitted on broad-spectrum antibiotics.

66 patients with septic shock warrant emergent broad-spectrum antibiotics.

67 version of Gram-positive-only compounds into broad-spectrum antibiotics.

68 ty testing often results in prolonged use of broad-spectrum antibiotics.

69 (2) the proportion of antibiotics that were broad-spectrum antibiotics; (3) the proportion of antibi

70 t the first inactive precursor of the potent broad-spectrum anticancer drug paclitaxel (a.k.a. Taxol)

71 nvestigational antiepileptic drug, has shown broad-spectrum anticonvulsant activity in preclinical st

72 entified as a suitable target for developing broad-spectrum anticytokine therapeutics for controlling

73 Importantly, compound 30 displayed a broad-spectrum antifilovirus activity against Bundibugyo

74 d in semisynthetic sordarin derivatives with broad spectrum antifungal activity.

75 lts justify future exploration of Cdc14 as a broad spectrum antifungal target for plant protection.

76 duced immunosuppressive activity and retains broad-spectrum antifungal activity and efficacy in a mur

77 erscoring the potential utility of H84T as a broad-spectrum antiinfluenza agent.

78 There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination

79 Due to their broad-spectrum antimicrobial activity, some bacteriocins

80 ainst gram-positive pathogens, verine showed broad-spectrum antimicrobial activity.

81 Broad-spectrum antimicrobial agents also increase the ri

82 The use of nontherapeutic broad-spectrum antimicrobial agents triclosan (TCS) and

83 Bovine lysozyme (BvLz) is a potent broad-spectrum antimicrobial enzyme used in the food, co

84 Broad-spectrum antimicrobial use is likely to be widespr

85 pital setting via telehealth, led to reduced broad-spectrum antimicrobial utilization, increased ID c

86 Ivermectin is an FDA-approved broad-spectrum antiparasitic agent with demonstrated ant

87 Ivermectin is an FDA-approved broad-spectrum antiparasitic drug that also exhibits ant

88 UV-4B has broad-spectrum antiviral activity against diverse viruse

89 RDV shows broad-spectrum antiviral activity against RNA viruses, a

90 other human pathogenic viruses, we observed broad-spectrum antiviral activity of these compounds bey

91 such interfacial activity is a correlate of broad-spectrum antiviral activity.

92 ay contribute to efforts aimed at developing broad-spectrum antiviral agents and help provide a more

93 thways, providing the possibility to develop broad-spectrum antiviral agents targeting host factors.

94 ace that govern recognition specificity by a broad-spectrum antiviral aptamer, and they open new poss

95 work defines the mammalian SKI complex as a broad-spectrum antiviral drug target and identifies lead

96 CoV-2) main protease (Mpro) is an attractive broad-spectrum antiviral drug target.

97 celerate the development of orally available broad-spectrum antiviral drugs to stop the current pande

98 nducible genes GBP2 and GBP5 that encode for broad-spectrum antiviral factors.

99 strategy in developing highly selective and broad-spectrum antiviral molecules active against emergi

100 Remdesivir is a broad-spectrum antiviral nucleotide prodrug that has bee

101 We have suggested that such broad-spectrum antiviral peptides share a property calle

102 uation of HSD17B12 inhibition as a promising broad-spectrum antiviral strategy for the treatment of F

103 ptimization, or molecular evolution of novel broad-spectrum antiviral therapeutics.IMPORTANCE New cla

104 Broad-spectrum antivirals are powerful weapons against d

105 ezers and establish a new class of potential broad-spectrum antivirals with enhanced activity.

106 ition for the development of ISG15-targeting broad-spectrum antivirals.

107 abolism, and pharmacokinetic properties, and broad-spectrum AR antagonist properties, including poten

108 The role of other broad-spectrum beta-lactams and the likelihood of ampC i

109 and approximately 32-minute time savings to broad-spectrum (beta = -0.32; 95% CI, -0.62 to -0.02) an

110 Few broad-spectrum BLs inhibitors were identified; among the

111 ay adverse renal outcomes than other empiric broad-spectrum combinations.

112 precipitation analyses pinpoint the UPR as a broad-spectrum compensatory response wherein LBS and pro

113 ole in horizontal gene transfer bolstered by broad-spectrum CRISPR-Cas9 inhibition.

114 e results demonstrate that the gRNAs possess broad-spectrum cutting activity and could contribute to

115 Disease onset, symptoms and mortality span a broad spectrum depending on the nature of the mutation a

116 opyridine-3,5-bis(thiocyanate) (PR-619) is a broad-spectrum deubiquitinating enzyme (DUB) inhibitor t

117 We hypothesised that broad-spectrum disease resistance alleles also affect co

118 an endogenous stress metabolite that induces broad-spectrum disease resistance in plants.

119 The durable, broad-spectrum disease resistance is caused by a loss-of

120 ow that introgressed QTL can greatly improve broad-spectrum disease resistance while having only limi

121 ce and yield, and how to generate crops with broad-spectrum disease resistance.

122 immunity, and advanced our understanding of broad-spectrum disease resistance.

123 -associated genes could contribute to SCA6's broad-spectrum disease resistance.

124 Overall, brief exposure to broad-spectrum disinfectants and direct steam could be u

125 ne the effectiveness of three commonly used, broad-spectrum disinfectants to cause mortality of D. vi

126 Despite frequent prescription of broad-spectrum empirical antimicrobials in patients with

127 Four compounds showed broad-spectrum EV and RV activity and inhibited contempo

128 In the event that a broad spectrum exercise mimetic might ever be developed,

129 e ranked into 4 categories: narrow spectrum, broad spectrum, extended spectrum, and agents targeted f

130 rice blast disease, but also show effective, broad-spectrum fungicidal activity against a wide range

131 s conjugated with Dexamethasone (mAv-Dex), a broad-spectrum glucocorticoid, using a combination of hy

132 e unit, 61% were treated empirically without broad-spectrum Gram-negative coverage, with clinical cur

133 HAP onset) identified patients not requiring broad-spectrum Gram-negative coverage.

134 different concentrations of JNJ-26481585, a broad-spectrum HDAC inhibitor.

135 ent work that the mammalian SKI complex is a broad-spectrum, host-directed, antiviral drug target.

136 ially important targets for the discovery of broad-spectrum human STN drugs.

137 ased design led to AA139, an antibiotic with broad-spectrum in vitro activity against multidrug-resis

138 FLU-v is a broad-spectrum influenza vaccine that induces antibodies

139 nd AcrIIA17 provide robust and highly potent broad-spectrum inhibition of distinct Cas9 proteins in h

140 m only a few viral clades, while others show broad-spectrum inhibition.

141 To develop a broad-spectrum inhibitor of influenza to combat the prob

142 ere, we tested the molecular tweezer CLR01-a broad-spectrum inhibitor of the self-assembly and toxici

143 hor of prions to create a membrane-tethered, broad-spectrum inhibitor, named T1(Pr alphaTACE), that c

144 g, and microbiological profiling to identify broad-spectrum inhibitors of both serine- and metallo-be

145 oronaviruses fostering the identification of broad-spectrum inhibitors.

146 ke CD27(-)CD28(-)CD8(+) T cells to acquire a broad-spectrum, innate-like killing activity.

147 VICE 3: When infected necrosis is suspected, broad-spectrum intravenous antibiotics with ability to p

148 structural framework for understanding how a broad-spectrum irritant receptor is controlled by endoge

149 ble and effective against diverse pathogens (broad-spectrum) is essential to stabilize crop productio

150 s using recombinant PKA, the response to the broad-spectrum kinase inhibitor H89 (N-[2-p-bromocinnamy

151 ted for the determination of azithromycin, a broad-spectrum macrolide antibiotic, from various biolog

152 Furthermore, treatment with the broad-spectrum matrix metalloproteinase inhibitor batima

153 Due to their broad-spectrum mechanism of action and enormous potentia

154 Our results provide the first report of a broad-spectrum mechanism regulating translation initiati

155 ic step in the production of staphylopine, a broad-spectrum metallophore, through the reductive conde

156 article (NP) that functions as an effective, broad-spectrum metalloproteinase inhibitor.

157 Our results suggest that current broad-spectrum molecular testing algorithms identify mos

158 potential as the basis for a novel class of broad-spectrum mycobacterial drugs.

159 Importantly, remdesivir, a broad-spectrum nucleoside analog that is effective again

160 s, thermophotovoltaic cells must utilize the broad spectrum of a radiative thermal source.

161 modulation of p75(NTR) signaling inhibits a broad spectrum of Abeta-triggered, tau-related molecular

162 Depending on the packaged cargo, EVs have a broad spectrum of action and are involved in pathogenesi

163 impeded proliferation of tumors harboring a broad spectrum of activated RTKs as the oncogenic driver

164 ce time, absorption and bioavailability of a broad spectrum of active compounds upon mucosal administ

165 Their broad spectrum of activity is attributed to their abilit

166 Sleep loss disrupts a broad spectrum of affective processes, from basic emotio

167 art failure and improved symptoms across the broad spectrum of age studied in DAPA-HF.

168 oot uptake and root to shoot allocation of a broad spectrum of amino acids in rice.

169 in yeast, OsLHT1 supported cell growth on a broad spectrum of amino acids, and effectively transport

170 A broad spectrum of analytical methods has become availabl

171 In turn, phages have evolved a broad spectrum of anti-CRISPRs that suppress these immun

172 patients, and the strains are resistant to a broad spectrum of antibiotics.

173 anes are a family of natural products with a broad spectrum of anticancer activity.

174 (RDV) is an investigational compound with a broad spectrum of antiviral activities against RNA virus

175 led to great advances in gene editing for a broad spectrum of applications.

176 placebo groups could be attributable to the broad spectrum of azithromycin activity and the study se

177 Metallo-beta-lactamases (MBLs) degrade a broad spectrum of beta-lactam antibiotics, and are a maj

178 lly disordered proteins (IDPs) can display a broad spectrum of binding modes and highly variable bind

179 Nuclear receptors have a broad spectrum of biological functions in normal physiol

180 prompt synapse pathology, contributing to a broad spectrum of brain disorders.

181 A broad spectrum of bridged dinitrogen heterocycles were o

182 ration, migration and invasion in vitro in a broad spectrum of cancer types and has therapeutic effic

183 esponses to more than 200 drugs inhibiting a broad spectrum of cancer-relevant targets.

184 Success across a broad spectrum of cancers has led to a paradigm shift in

185 Cancer therapies can lead to a broad spectrum of cardiovascular complications.

186 e viral immunomodulatory protein targeting a broad spectrum of cell surface molecules involved in the

187 s interaction rewiring across a surprisingly broad spectrum of cellular pathways in the antiviral res

188 an cytomegalovirus (HCMV) infection causes a broad spectrum of central and peripheral nervous system

189 erstanding of these processes by detecting a broad spectrum of chemicals.

190 RAG1 and RAG2 represent the prototype of the broad spectrum of clinical and immunological phenotypes

191 rdiovascular (CV) diseases is divided into a broad spectrum of clinical entities.

192 ; increased chromosome missegregation; and a broad spectrum of clinical features, including various c

193 infection typically results in meningitis, a broad spectrum of CNS involvement and severity is emergi

194 ography provides important insights into the broad spectrum of disease which comprise the inflammator

195 rial dysfunction underlies the etiology of a broad spectrum of diseases including heart disease, canc

196 These 'dyneinopathies' define a broad spectrum of diseases with no known correlation bet

197 inally differentiated cells contributes to a broad spectrum of disorders.

198 ndividual consideration, thereby revealing a broad spectrum of diversity as well as identifying extre

199 ropose that Pseudomonas jumbo phages evade a broad spectrum of DNA-targeting nucleases through the as

200 y a leading INSTI retains efficacy against a broad spectrum of drug-resistant variants.

201 can be optimized by directed evolution for a broad spectrum of enantioselective C(sp(3))-H amination

202 imited to specific infections, and affects a broad spectrum of enteric pathogens.

203 tituent conveys excellent activity against a broad spectrum of ESKAPE pathogens and other Gram-negati

204 nd provides a series of 'snapshots' across a broad spectrum of eukaryotic organisms.

205 lfonylated indazole derivatives containing a broad spectrum of functional groups were synthesized in

206 adipocyte-derived hormone adiponectin has a broad spectrum of functions beyond metabolic control.

207 le, reproducible, and readily adaptable to a broad spectrum of fundamental questions in biology.

208 ere support the view that CDC belongs to the broad spectrum of fungal-associated immune reconstitutio

209 We show a broad spectrum of fusion inhibition by GA of all three c

210 onism of Fzd5 and/or Fzd8 receptors, while a broad spectrum of Fzd receptors can induce liver zonatio

211 ic landscape of glioma in the CSF included a broad spectrum of genetic alterations and closely resemb

212 alleles and demonstrate the coexistence of a broad spectrum of genome configurations in a cell popula

213 Antibiotics with a broad spectrum of gram-negative activity accounted for 3

214 Antibiotics with a broad spectrum of gram-negative activity accounted for a

215 mit the intramolecular cyclopropanation of a broad spectrum of homoallylic diazoacetate substrates in

216 rum, causes white mold disease and infects a broad spectrum of host plants (> 500), including soybean

217 phylococcus aureus is capable of infecting a broad spectrum of host tissues, in part due to flexibili

218 h the microevolution and macroevolution of a broad spectrum of hues.

219 cian awareness, which is necessary given the broad spectrum of ICI toxicities often experienced by pa

220 polymorphic AIPL1 gene are associated with a broad spectrum of inherited retinal diseases ranging fro

221 This compound displays a remarkably broad spectrum of inhibition, including class B and clas

222 wever, TSLP, IL-33, and IL-25 all regulate a broad spectrum of innate immune cell populations and are

223 l tyrosine kinase inhibitor active against a broad spectrum of KIT and PDGFRA mutations, with placebo

224 compete with (18)F-FDG for evaluation of the broad spectrum of malignancies.

225 50) enzymes on the magnetic beads provided a broad spectrum of metabolic enzymes.

226 Samples of all colors were analyzed with a broad spectrum of methods to assess their physico-chemic

227 y in a consecutive series of patients with a broad spectrum of neurodegenerative conditions.

228 red to as STXBP1 encephalopathy, encompass a broad spectrum of neurologic and psychiatric features, b

229 us, opening up the possibility of studying a broad spectrum of neurological conditions in vivo.

230 een linked to suicide, but the risk across a broad spectrum of neurological disorders remains to be a

231 ne (DA) signaling has been associated with a broad spectrum of neuropsychiatric disorders, prompting

232 gulated microRNAs (miRNAs) are involved in a broad spectrum of NSDs.

233 nificantly shorten the synthetic period of a broad spectrum of open organic materials presents an ent

234 s, suggesting that similar events occur in a broad spectrum of pathologies.

235 of commercial products worldwide due to its broad spectrum of physical properties and low production

236 ane proteins involved in the regulation of a broad spectrum of physiological processes and are a majo

237 showed significant changes in the level of a broad spectrum of plasma proteins including serine prote

238 ion closely matched manual analysis across a broad spectrum of populations.

239 s would require studies that both evaluate a broad spectrum of posttraumatic sequelae (to overcome fr

240 WCNT species are calculated, which reveals a broad spectrum of potentially achievable colors of SWCNT

241 Fibers are the building blocks of a broad spectrum of products from textiles to composites,

242 resistance gene and confers resistance to a broad spectrum of Pst races.

243 Risks for a broad spectrum of psychiatric diagnoses are significantl

244 not a unitary disease entity, encompassing a broad spectrum of psychopathology arising from distinct

245 in many eukaryotic lineages, resulting in a broad spectrum of reduced and modified mitochondrion-rel

246 ed in various experimental contexts across a broad spectrum of research areas.

247 GATA2 deficiency is associated with a broad spectrum of rheumatological disease manifestations

248 many studies in kidney transplantation and a broad spectrum of risk factors has been identified, the

249 d polymorphism of F-box genes well support a broad spectrum of SCF functions, experimental evidence i

250 e approach to fabricate nanographenes with a broad spectrum of semiconducting properties and high cha

251 nded this analysis to 679 diseases to test a broad spectrum of side effects associated with hypotheti

252 Here, we review a broad spectrum of single-molecule tools and techniques s

253 global sustainability challenges, there is a broad spectrum of societal needs where the development o

254 induce antitumor immune responses against a broad spectrum of solid tumors.

255 microearthquakes and geochemical data over a broad spectrum of spreading rates, but such data have no

256 Given the broad spectrum of Strand-seq applications we expect brea

257 Across a broad spectrum of subjects with cardiometabolic disease,

258 ing and acid-catalysed reactions, spanning a broad spectrum of substrates including sugars and platfo

259 Matrix metalloproteinases have a broad spectrum of substrates ranging from extracellular

260 Organisms can adapt to a broad spectrum of sudden and dramatic changes in their e

261 Due to the broad spectrum of targeted organisms, FA-M/E testing may

262 d II and reveal how teixobactins recognize a broad spectrum of targets.

263 thracyclines in the United States due to its broad spectrum of therapeutic efficacy.

264 review articles have extensively examined a broad spectrum of these SSEs using evaluation factors su

265 bnormally high extracellular Pi results in a broad spectrum of toxicity by rewiring complicated signa

266 BC200 is a noncoding RNA elevated in a broad spectrum of tumor cells that is critical for cell

267 BAP1 is mutated in a broad spectrum of tumors.

268 ith IC(100) as low as 0.04 mug/mL, showing a broad spectrum of variable (V) genes and low levels of s

269 These are very heterogeneous, resulting in a broad spectrum of vesicular release probabilities within

270 nstrated potent antiviral activity against a broad spectrum of viruses in multiple in vivo disease mo

271 eloped using a large VF dataset containing a broad spectrum of visual deficit types, has the potentia

272 een shown to be important for virulence in a broad-spectrum of pathogenic bacteria.

273 a simple-to-use aptasensor to rapidly detect broad-spectrum OPs with high sensitivity.

274 limited sequence space, and can be tuned for broad-spectrum or specific activity against microorganis

275 from clinical samples, has proved useful for broad-spectrum pathogen detection and the genomic survei

276 orizing them into pan-HIF-alpha hydroxylase (broad spectrum), PHD-selective, and FIH-selective inhibi

277 ned variation of antibiotic prescription and broad-spectrum prescription by calculating standardised

278 to narrow-spectrum prescriptions by dividing broad-spectrum prescription rates by narrow-spectrum pre

279 ean EDs covering diversity in antibiotic and broad-spectrum prescriptions in all febrile children are

280 2008, Victoria lineage), demonstrating their broad-spectrum prophylactic and therapeutic activity aga

281 Our results suggest that Fpn is a broad-spectrum protease that not only catalyzes the prot

282 D614G variant, indicating the potential for broad spectrum protection.

283 Trained immunity confers broad-spectrum protection against lethal bacterial infec

284 0 min) and to administration of the complete broad-spectrum regimen was 108 minutes (66-144 min) vers

285 sion of multidrug efflux pumps often creates broad-spectrum resistance in cancers and pathogens.

286 rom wild relatives could be used to engineer broad-spectrum resistance in domesticated crops.

287 Broad-spectrum resistance is highly preferred in crop br

288 ce (Oryza sativa) NLR receptor Piz-t confers broad-spectrum resistance to the fungal pathogen Magnapo

289 underlying a QTL conferring quantitative and broad-spectrum resistance to X campestris RKS1-dependent

290 , we have reported the identification of the broad-spectrum resistance-Digu 1 (bsr-d1) allele from ri

291 )O USNPs) with multiple enzyme-mimicking and broad-spectrum ROS scavenging ability for the treatment

292 th high solubility, low cytotoxicity, potent broad-spectrum sterilizing activity against a panel of g

293 ana benthamiana, suggesting that it may be a broad-spectrum suppressor of plant immunity.

294 its combination with itraconazole displayed broad-spectrum synergistic interactions against Candida

295 Pitavastatin displayed broad-spectrum synergistic interactions with both flucon

296 sed small molecule-based toxin inhibitors as broad-spectrum therapeutics for snakebite.

297 ctrum antibiotics, most were still receiving broad-spectrum therapy 3 days later, but UAT-positive pa

298 type and presents an opportunity to identify broad-spectrum treatments to mitigate the most severe ma

299 tigated the interface between HIV-1 RT and a broad-spectrum UCAA-family aptamer.

300 g "translocon unclogger" and (non-enyzmatic) broad-spectrum viral restriction factor, presents far di