ライフサイエンスコーパス: broaden

1 xpands and the needs of patients continue to broaden.

2 d dramatically and the term's visibility has broadened.

3 ogies, the potential of NIRFI can be greatly broadened.

4 ncy shifts and the ionisation thresholds are broadened.

5 tion is favored by adduct absorption spectra broadening.

6 n to make considerable contributions to band broadening.

7 ase in delta(15)N and TL, coupled with niche broadening.

8 , exchange-induced shifts, and lifetime line broadening.

9 of the exciton frequencies governs spectral broadening.

10 ructure and displays a ~1 cm(-1) shift and a broadening above ~2 cm(-1), as well as a relative intens

11 ng near-infrared nonfullerene acceptors with broadening absorption that pair with commercialized dono

12 vailable for immediate clinical use, thereby broadening access and applicability.

13 hetic, systems, and evolutionary biology and broadens access to cutting-edge research capabilities.

14 facture, could dramatically reduce costs and broaden accessibility.

15 mpounds with increased antiviral potency and broadened activity.

16 This approach provides a new method to broaden and potentially extend protective immune respons

17 r perturbation conditions, which may greatly broaden and promote the applications of both MOFs and bi

18 on number while the bond angle distributions broaden and shift to smaller angles.

19 identify critical amino acid exchanges that broaden and swap their lipid specificities.

20 ke recommendations for how progress might be broadened and accelerated.

21 Recent advances have significantly broadened and deepened our understanding of how bacteria

22 e of the Rh6 visual pigment is substantially broadened and its peak sensitivity is shifted by 92 nm f

23 particles can both reduce mobile-phase band broadening and increase permeability compared with spher

24 00 M(-1)cm(-1) in free ferrocene) as well as broadening and red-shifting of the ferrocenyl transition

25 ormation as a source of chromatographic band broadening and rupturing as a mode of column failure.

26 However, relaxation-induced line broadening and signal overlap make it challenging to app

27 f-resonance R (1rho) profiles, lifetime line broadening, and exchange-induced shifts) on the CTD of b

28 riant) based on A/New Caledonia/20/99 (H1N1) broadens antibody responses to cross-react with group 2

29 This enhanced protocol should broaden applicability of HSC gene editing and pave its w

30 ctionality will have a substantial impact in broadening application of CAR-T cell therapy, especially

31 phy research toward issues to be resolved to broaden applications is discussed.

32 To broaden applications of origami designs, we introduce an

33 he excited state lifetimes inferred from the broadening are considered in the context of fluctuations

34 to the presence of the reflections and beam broadening arising from the quasi-conformal mapping.

35 ith experiment, revealing a decrease in peak broadening as the salt concentration increases.

36 g, we show that the dominance of homogeneous broadening at the exciton level results from exchange na

37 This broadened bandwidth of Ca(2+) influx is translated by ce

38 rmline CDR1beta- and CDR2beta-MHC binding to broaden beta-chain repertoire diversification before alp

39 ic core collection that can be used for base-broadening breeding aimed at efficient introgression of

40 pattern evoked, or a more pronounced spiked broadening, but correlated with higher dendritic Ca(2+)

41 n and was not accompanied by increased spike broadening, but correlated with higher dendritic Ca(2+)

42 microbial armamentarium could potentially be broadened by DAU, DMDM, SMG and other FARs for antibioti

43 , it is not fundamentally limited and can be broadened by engineering selective optical coupling mech

44 The antibody repertoire is broadened by the extended NA and includes additional ADC

45 Where this strategy is not sufficient, the broadening can be reduced further by rapidly switching t

46 e circular chromosome in live E. coli with a broadened cell shape.

47 erally applied to advance engineering of the broadening class of polymer materials with dynamic cross

48 he vaginal ecosystem during menstruation has broadened current understanding of the disease, and the

49 rk implemented Share 35 on June 18, 2013, to broaden deceased donor liver sharing within regional bou

50 ier hopping and thermalization in a disorder-broadened density of states (DOS).

51 gnments employing major isomer-specific peak broadening due to unresolved isotopomer mixtures.

52 ence of EVALI highlighting the importance of broadening e-cigarette research beyond comparators to sm

53 challenging using conventional probes due to broadening effects from radiation damping.

54 n preventing systematic biases from pressure broadening effects when using these reference materials

55 tron beam parameter and the diffraction peak broadening enables a real-time nondestructive diagnosis

56 er parameters during loading can reduce this broadening, enabling state-selective ionisation in some

57 To broaden evidence for Ars2 as a chromatin regulator in ne

58 ddition, we describe research pipelines that broaden evidence-based approaches and the pathobiology o

59 These "Broadening Experiences in Scientific Training" (BEST) aw

60 We show that broadening fluctuations around naturally male-producing

61 t by junctional complexes between abnormally broadened foot processes.

62 tened arousal, as indexed by pupil diameter, broadens frequency-tuned activity of layer 2/3 (L2/3) py

63 nome tends to increase infection efficiency, broaden host range, and potentially increase attachment

64 pherical core, generating a vaccine that can broaden immune responses against known pathogenic Ebola

65 her in polymer nanoparticles (NP), elicits a broadened immune responses in mouse bone marrow-derived

66 immune protein human calprotectin (hCP) has broadened in recent years, understanding of its Ca(2+)-b

67 ty of surface random walks could reduce peak broadening in full-scale protein separations.

68 density of magnetic centers results in line-broadening in magnetic resonance spectra.

69 de dynamics are detected in the form of line broadening, indicative of mus-to-ms timescale conformati

70 To broaden inference, TBM simulations were run and novel, h

71 e subtle in that the Parisi overlap function broadens instead of completely changing shape.

72 To circumvent spin-spin broadening, iron and nickel atoms were doped into nonmag

73 is possible because magnetic susceptibility broadening is negligible at ultralow magnetic fields.

74 insight into low-voltage electroadhesion and broaden its possible applications.

75 reported to not activate G proteins but can broaden its signaling spectrum upon heteromerization wit

76 heterodimerization with either TLR1 or TLR6, broadening its ligand diversity against pathogens.

77 unctional investigatory approaches that help broaden knowledge of mammals' memorable external appeara

78 function and data treatment using a Doppler-broadened, low-pressure gas sample are discussed.

79 further investigation, with the potential to broaden ML NK cell recognition against a variety of NK c

80 change saturation transfer and lifetime line broadening NMR data.

81 We demonstrate the utility of this broadened notion by using it to identify known phenologs

82 tability, based on a Na(+) channel-dependent broadening of backpropagating action potentials.

83 djacent melt pools, resulting in substantial broadening of grains.

84 ure is likely to increase in tandem with the broadening of legalization and acceptance of the drug. A

85 in obtaining high Mn contents, considerable broadening of QD size dispersion during the doping proce

86 bulk magnetic susceptibility (ABMS) leads to broadening of resonances under magic angle spinning, we

87 ectrode, which gives rise to the diffusional broadening of surface features.

88 number of new trends are noted, for example, broadening of target class coverage and application of F

89 ational tool could support safe planning and broadening of TAVI.

90 R shift of the water resonance) and the line broadening of the (1)H shifts of the quinone resonances

91 Genetic depletion of K(v)beta1 blocked all broadening of the AP(syn) during high-frequency stimulat

92 We also observe a broadening of the diffraction peaks which is greater for

93 ow a material-dependent onset, including the broadening of the glass transition and the homogenizatio

94 in ion traps, we have simulated the expected broadening of the ionisation threshold under various ope

95 e text] and/or enhancement of in-homogeneous broadening of the oscillations in magnetic field B.

96 als, establishing processing guidelines, and broadening of the range of applications.

97 The inhomogeneous broadening of the spectrum was linked to the vibrational

98 nothread crystals that can contribute to the broadening of their diffraction spots, and electron ener

99 that heteroatom doping not only results in a broadened operating voltage, but also successfully promo

100 nes on these growth modes: SHOOTMERISTEMLESS broadens organ-wide growth relative to edge-patterning,

101 Together, the results of this study broaden our appreciation for circRNA repertoires in the

102 To broaden our approach to allosteric inhibition of SHP2, w

103 ly aid in nanomaterial applications but also broaden our knowledge of cell biology.

104 These findings broaden our knowledge on the indigenous Indian herb H. e

105 targeting G(q) protein oncogenes as well as broaden our mechanistic understanding of G(q) protein on

106 s, states, and developmental trajectories to broaden our understanding of cellular heterogeneity in t

107 These findings broaden our understanding of host modulation of the micr

108 These results broaden our understanding of molecular genetic pathology

109 These data help broaden our understanding of the everyday-life impact of

110 nal ancient pathogens, with the potential to broaden our understanding of the infectious disease burd

111 These results broaden our understanding of the microcircuits supportin

112 These findings broaden our understanding of the molecular dysfunctions

113 Our results may broaden our understanding of the response of a microbial

114 These findings will help to broaden our understanding regarding the physiological an

115 g, and gene editing tools have substantially broadened our ability to generate various types of organ

116 at linked intestinal microbiota and CVD have broadened our understanding of how dietary nutrients may

117 Altogether, this study has greatly broadened our understanding of pelagiphages regarding th

118 Super-resolution microscopy is broadening our in-depth understanding of cellular struct

119 h infection in such systems is important for broadening our knowledge of parasite ecology and provide

120 atalytic mechanism of a PL36 alginate lyase, broadening our knowledge on alginate lyases and facilita

121 atmospheres of rocky exoplanets, potentially broadening our knowledge on the diversity of exoplanetar

122 ountries from those of western nations, thus broadening our picture of human-wildlife interactions in

123 Broadening our scope to cytochrome c and lysozyme, we sh

124 s progress has been made in plant pathology, broadening our understanding of how pathogens colonize t

125 zation of minicircles and gRNAs in T. lewisi broadens our knowledge of the structure and expression o

126 It broadens our understanding of biologically-mediated iron

127 Our finding broadens our understanding of the ways in which animal m

128 This viral reservoir profile broadens our understanding of virus persistence in a rel

129 expanded understanding of Tn7-like elements broadens our view of how genetic systems are repurposed

130 We find that activation energy distributions broaden over time in all mineral-containing samples.

131 Biosimilars have the potential to broaden patient access to biologics and provide cost sav

132 ity, and so on tend to lead to significantly broadened peaks.

133 nrecordable in a few subjects or exhibited a broadened profile which precluded peak identification.

134 duction programmes that leverage networks to broaden programmatic effects, there is little evidence t

135 P[6]-based rotavirus vaccines could broaden protection in such settings, particularly in Afr

136 Our findings uncover a broadened PSEN1 role in lysosomal ion homeostasis and no

137 progress in combatting poverty, PSID's scope broadened quickly to a variety of topics and fields of i

138 We anticipate our results to broaden research directions in physics-inspired computin

139 eristics for most organ types have generally broadened, resulting in the need to consider more comple

140 nt but limited; subordinated task-doers; and broadening scope and strengthened identity.

141 ion can also be expected, in addition to the broadening set of cancer therapeutics that can induce pr

142 approach presented here has the potential to broaden significantly the applicability of selective exc

143 erials show poor catalytic activity due to a broadened single resonance derived from the interaction

144 ion occurs from a very wide, inhomogeneously broadened spectral line with time-averaged single ensemb

145 The other extension concerns the broadened spectrum of compositions within the aforementi

146 Fungal infections are being caused by a broadening spectrum of fungi, yet in many cases, identif

147 evealed that rapid spectral energy shift and broadening started within the first 10 fs of the X-ray i

148 ) at or near room temperature, but hyperfine broadening, susceptibility to magnetic field heterogenei

149 and cell manufacturing have the potential to broaden T cell-based therapies and foster new applicatio

150 f many cancers, may offer the potential of a broadened target space.

151 l as future potential targets and methods to broaden the applicability of virus-directed T-cell immun

152 small-sized and ultrathin M-NSs, which will broaden the application of 2D nanomaterials.

153 to optimise efficacy, minimise toxicity, and broaden the application of immunotherapies based on T ce

154 ics beyond the proteomics community and will broaden the application of proteogenomics in personalize

155 This new class of tension sensors will broaden the application of tension sensors in the study

156 s and their derivatives, which would further broaden the application opportunities of metal-organic f

157 structure-property relationship, as well as broaden the application space for MHPs.

158 titative exchanged-label turnover MRS should broaden the applications of routine (1)H MRS.

159 ordered, anisotropic nanomaterials but also broaden the available toolbox for in situ tracking of na

160 A main challenge to broaden the biomedical application of CRISPR/Cas9 (clust

161 Our results significantly broaden the catalytic scope of polymerase activity and s

162 struction of architectures within cells will broaden the community's perspective toward how structure

163 n utilization of sacrificial Mg alloys could broaden the current palette of antibacterial platforms f

164 ion principle of "superelectrophiles" and to broaden the current scope of catalytic carbonyl-olefin m

165 Here, we broaden the definition of BRCAness to include RFP and re

166 The CcCas9 can potentially broaden the existing scope of biotechnological applicati

167 ies (EWAS), to increase sample sizes, and to broaden the focus to include all eating disorder types.

168 range of the misfit spectrum to enhance and broaden the functionality of semiconductor devices for a

169 tribute to the observed muscle pathology and broaden the genetic spectrum of LGMD myopathies.

170 In this report, we sought to broaden the genotype-phenotype spectrum of calmodulinopa

171 briefly introduced and recent advances which broaden the horizons of this technique in novel material

172 To broaden the insight into the organization and regulation

173 acting regions (LIRs) in several SNAREs that broaden the landscape of the mAtg8-SNARE interactions.

174 Moreover, long columns-in theory-just broaden the peaks of large solutes since a great part of

175 nstructively couple many more resonances and broaden the perfect absorption bandwidth.

176 These results should broaden the performance and applications of electrochemi

177 Our observations broaden the polyketide biosynthetic landscape and identi

178 To that end, this work looks to broaden the prevailing view: laying the foundation for t

179 These data both broaden the putative roles for immune cells in the devel

180 l to that of SpCas9 and thus potentially can broaden the range of Cas9 applications in biomedicine an

181 ugh expressing many diverse MHC genes should broaden the range of detectable pathogens, it has been h

182 e BG505 glycan hole epitope in an attempt to broaden the reactivity of a B41-specific nAb, but we rec

183 nces in genomics and proteomics, promises to broaden the responder patient population.

184 In conclusion, our data broaden the role of the RLR family to include a role in

185 ps of patches and thus have the potential to broaden the scope for empirical evaluations of the MVT a

186 Those studies could broaden the scope for the application of the label-free

187 oying MOFs in electrochemistry would notably broaden the scope of electrocatalysis.

188 eling of plants and other systems to further broaden the scope of in silico metabolic investigation.

189 Exchanging Ni(II) for other metal ions could broaden the scope of metalloenzyme target.

190 eting data on the outer skin's structure and broaden the scope of molecular-based methods to improve

191 ly stiffened materials and may significantly broaden the scope of polymer applications.

192 prioritizing nutrients for DRI review and to broaden the scope of the DRIs to better incorporate the

193 d cleavage of C-C bonds has the potential to broaden the scope of this type of skeletal remodeling by

194 In order to broaden the spectra of appropriate bentonites, we invest

195 To broaden the spectrum of applicable PET tracers for exten

196 ; for this reason, it sometimes necessary to broaden the study to include the brain.

197 rates and fish) suggesting there is scope to broaden the taxonomic range of attempted eradication in

198 Preclinical and clinical studies aiming to broaden the therapeutic application of PARPis identified

199 an approach to treat CLN3 Batten disease and broaden the therapeutic landscape for ASOs in the treatm

200 e need to routinely test for NTRK fusions to broaden the therapeutic options available for patients w

201 ery nanocarriers reported so far, and it can broaden the therapeutic promise of mRNA and CRISPR/Cas9

202 the basonuclin 2 (BNC2) gene in EOC risk and broaden the understanding of ovarian cancer biology.See

203 approaches and areas in which they will help broaden the utility and clinical applicability of stem c

204 d identifies MET/FAK as a tractable route to broaden the utility of CDK4/6 inhibitor-based therapies

205 To broaden the utilization of HECD in proteomic studies and

206 metal nanoclusters (NCs) have significantly broadened the accessible sizes and structures.

207 These tools have dramatically broadened the capabilities of EPR dynamics analysis, how

208 transmembrane residues 22-31 that ultimately broadened the drug-binding site of AM2 S31N inhibitor 4,

209 tant of barley (Hordeum vulgare) has greatly broadened the field of chloroplast biology, including th

210 ergence of powerful new molecular tools have broadened the number of avenues to target neurological d

211 Advances in organoid technology have broadened the number of target diseases and conditions i

212 system-based fisheries management (EBFM) has broadened the policy scope of fisheries management by ac

213 onses revealed that co-administration of NEI broadened the profile of cytokine responses, by stimulat

214 ey-paired donation (KPD) clearinghouses have broadened the transplant modalities available to HS cand

215 RhCMV infection of nonhuman primates greatly broadened the understanding of mechanisms by which CMVs

216 d IRMPD on commercial mass spectrometers and broadening the accessibility of these techniques.

217 aits' and means to address the challenges of broadening the applicability of functional traits to mac

218 er ultrathin oxides, opening up an avenue in broadening the applicaitons of ultrathin oxides in many

219 crobial peptide products, are candidates for broadening the available choices of antimicrobials.

220 dneys in normal and pathological conditions, broadening the biomedical applications of engineered nan

221 hat host range expansion could be predicted, broadening the classical definition of antireceptors to

222 ctor receptor (EGFR) therapeutic antibodies, broadening the concept of targeted EGFR therapy to encom

223 Our results contribute to broadening the debate beyond food security from a social

224 eads to more-nested but less-modular webs by broadening the diet of consumers at intermediate trophic

225 bolism of plant tissues and is implicated in broadening the diversity of plants eaten.

226 iotic agents and floral physiological costs, broadening the drivers of floral traits beyond pollinato

227 Broadening the genetic base of crops is crucial for deve

228 Our study contributed significantly to broadening the knowledge about HBV composition and shoul

229 These results are promising in terms of broadening the knowledge of many neurological diseases b

230 safeguarding against biological threats and broadening the pool of bioaerosol knowledge.

231 uestions of relatedness and flock size, thus broadening the potential possible applications of this s

232 y boost the sensitivity while simultaneously broadening the pressure responding range.

233 Here we suggest broadening the range of morphological, physiological and

234 range of possible DNA sequence alterations, broadening the research applications of CRISPR base edit

235 n, SmI(2) transforms into SmCl(2), therefore broadening the scope of accessible reactions.

236 nerating 2-deoxy O-glycosides, significantly broadening the scope of the approach.

237 a critical role in enhancing sensitivity and broadening the spectral range.

238 KDM4B variation leads to a chromatinopathy, broadening the spectrum of this group of Mendelian disor

239 clones that can target new epitopes, thereby broadening the spectrum of vaccine-induced protective an

240 Broadening the substrate scope of this evolutionarily na

241 ntial in improving targeting specificity and broadening the targeting range.

242 This study has implications for broadening the therapeutic utility of known targeted can

243 This largely broadens the absorption spectrum in very reasonable agre

244 We propose a new VBGF framework that broadens the applicability and increases flexibility of

245 Our finding broadens the applicability of d band theory to activity

246 Our work broadens the applicability of kinetic proofreading and s

247 dicinally important scaffolds, which further broadens the application of this new carbonylation metho

248 ion is an innovative targeting approach that broadens the available small molecule toolbox and is pro

249 This observation considerably broadens the class of possible interactions that result

250 omplex for meiotic recombination, this study broadens the conceptual scope of pioneer factors, indica

251 ation method was employed that substantially broadens the coverage of milk oligosaccharides and there

252 n agreement with theory, which significantly broadens the criteria for the search for new electride m

253 This broadens the existing cellular DNA adductome and offers

254 to other building blocks and topologies, and broadens the family and scope of COFs.

255 the oxygen lattice in reversible l-OR, which broadens the horizon for designing high-energy-density L

256 Our study broadens the known target specificity of GNAT toxins bey

257 gth scale two orders of magnitude larger and broadens the methods for nanomaterial fabrication.

258 Our study broadens the mutation spectrum of human tooth agenesis a

259 ype model established for ABCA4 variants and broadens the mutational spectrum of the gene.

260 n severe autosomal-dominant microcephaly and broadens the phenotypic spectrum of the laminopathies.

261 iches the diversities of nanozymes, but also broadens the promising applications of nanozymes in the

262 This broadens the range of materials and properties available

263 trode for optimum throughput performance and broadens the scope of applications for this emerging tec

264 This reactivity paradigm, which broadens the scope of aryl donor partners to homoenolate

265 Overall, this reaction broadens the scope of Cr-mediated carbonyl alkylations a

266 This paradigm broadens the scope of problems that can be investigated

267 ation of VARS in pediatric neurodegeneration broadens the spectrum of human diseases due to mutations

268 A rates-focused framework broadens the strategic menu for managers to include opti

269 chemistry of Li-insertion cathodes but also broadens the understanding of alkali metal alloys and hy

270 G beyond canonical amines thus substantially broadens the versatility of the enzyme, providing a new

271 mposition during the charging process, which broadens the voltage window of aqueous electrolytes even

272 the aquatic environment would significantly broaden their application potential in biomedical device

273 queous environment, which will significantly broaden their applications not only in optoelectronics b

274 with other cancer therapies to increase and broaden their efficacy.

275 enues for improving bioplastic properties to broaden their food packaging applications are critically

276 T(1T') phases in measurable quantities would broaden their prospective applications and practical uti

277 he safety and efficacy of gene therapies and broaden their use.

278 ties and limitations, and major efforts have broadened their editing capabilities, expanded their tar

279 e of both technologies has rapidly improved, broadening their applications.

280 Genes can encode multiple isoforms, broadening their functions and providing a molecular sub

281 cell receptor-mediated signals-substantially broadening their likely impact in health and disease.

282 therapies, increasing potency and safety and broadening their potential for treatment of disease.

283 e need to routinely test for ROS1 fusions to broaden therapeutic options for patients with ROS1 fusio

284 We broaden this idea to discuss potential relationships bet

285 Furthermore, the cardiotoxicity spectrum has broadened to include myocarditis with immune checkpoint

286 t that evaluation of such processes might be broadened to include uniform downscaling on the presynap

287 When the AI's top prediction was broadened to its top three most likely predictions, accu

288 It can be readily broadened to other receptor-cell surface ligand interact

289 te LEDs, the emission spectrum line width is broadened to over 25 nm by the coexistence of multiple r

290 COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of i

291 co-housing experiments, excitatory responses broadened to represent a wider range of ISIs, whereas in

292 but this design often added additional line-broadening to the bulk water signal due to T(2) exchange

293 Band broadening was less significant in the case in which an

294 From the lineshape broadening we determine the diffusion coefficient, the d

295 However, due to magnetic susceptibility broadening, which produces broad lines in one-dimensiona

296 i-solvent drip yields efficient solar cells, broadened with the increasing complexity of cation/halid

297 ance effect exhibits substantially increased broadening with increasing microwave intensity.

298 roscale improvements in chromatographic peak broadening with microscale distributions of surface inte

299 : see text] The bottlebrush correlation peak broadens with decreasing grafting density, similar to in

300 ry and simulation of nu(NH) vibrational band broadening, with the electron transfer efficiencies comp