ライフサイエンスコーパス: bronchial epithelium

1 enotypes and with IL33 expression in lung or bronchial epithelium.

2 n lungs and of interferon-sensitive genes in bronchial epithelium.

3 motility and colonization of differentiated bronchial epithelium.

4 ic inclusion bodies in the acute KD ciliated bronchial epithelium.

5 converting enzyme-2 (ACE2) expression within bronchial epithelium.

6 tive spheroidal antigen in acute KD ciliated bronchial epithelium.

7 ic inclusion bodies in the acute KD ciliated bronchial epithelium.

8 ation of the RASSFIA was not detected in the bronchial epithelium.

9 lial site, or unmethylated in both tumor and bronchial epithelium.

10 fibroblasts, and primary cultures of normal bronchial epithelium.

11 alveolar type II cells, and in tracheal and bronchial epithelium.

12 ons that have been examined in preneoplastic bronchial epithelium.

13 an brain tissue, non-SCLC tumors, and normal bronchial epithelium.

14 d found that IP-10 mRNA was expressed in the bronchial epithelium.

15 or establishment of the endodermally derived bronchial epithelium.

16 th the exception of the endodermally derived bronchial epithelium.

17 re also deficient in populating the layer of bronchial epithelium.

18 ction against severe RSV infection in infant bronchial epithelium.

19 xtensive apoptotic cell death only in infant bronchial epithelium.

20 based on the gene expression profile in the bronchial epithelium.

21 cytoskeleton and disturb homeostasis of the bronchial epithelium.

22 ) based on their localization underneath the bronchial epithelium.

23 ly involved in protection and maintenance of bronchial epithelium.

24 ch GSDMB induces 5-LO to induce TGF-beta1 in bronchial epithelium.

25 tory syndrome coronavirus 2 receptor ACE2 in bronchial epithelium.

26 DSB marker gamma Histone 2AX (H2AX) foci in bronchial epithelium.

27 issue samples and quantified in alveolar and bronchial epithelium.

28 dysfunction and pro-inflammatory activity of bronchial epithelium.

29 levant cell line, Calu-3, derived from human bronchial epithelium.

30 ion of genes inducible by T(H)2 cytokines in bronchial epithelium.

31 ssed primarily in tumor cells along with the bronchial epithelium.

32 s only observed in ciliated cells, not basal bronchial epithelium.

33 vailable experimental data of cultured human bronchial epithelium.

34 ICAM-2, but not ICAM-3, is expressed on the bronchial epithelium.

35 lls but not in normal mucous NHTBE or normal bronchial epithelium.

36 ormal human stem cells from blood, liver and bronchial epithelium(5-12).

37 lesions, 47%) than in histologically normal bronchial epithelium (63 of 323 specimens, 20%; P < 0.00

38 of cells staining for mucus was seen in the bronchial epithelium, a feature more commonly associated

39 ew HIF2alpha-dependent mechanism involved in bronchial epithelium adaptation to oxygen fluctuations.

40 ted into human airway epithelial cells [both bronchial epithelium + adenovirus 12 - SV40 hybrid (BEAS

41 n with Mycobacterium paratuberculosis and in bronchial epithelium after acute infection with Pasteure

42 striking induction in pIgR expression by the bronchial epithelium and a subsequent increase in airway

43 ed DNA damage and cytokine production in the bronchial epithelium and apoptosis in the allergic airwa

44 edly increases in hypertrophic, hyperplastic bronchial epithelium and appears in type II alveolar pne

45 GS2 was highly expressed in human and murine bronchial epithelium and ASM and was markedly downregula

46 Bronchial epithelium and ASM expressed IL-33 with the la

47 mmasome sensor in both healthy and asthmatic bronchial epithelium and can be activated by RV-A16.

48 selectively targets ciliated cells in human bronchial epithelium and can cause bronchiolitis and pne

49 ociation seen between p16 methylation in the bronchial epithelium and corresponding primary tumor sub

50 ation to be deranged in the severe asthmatic bronchial epithelium and fibroblasts compared to their h

51 d RRM2) were upregulated in severe asthmatic bronchial epithelium and fibroblasts, (SFN, ABCA1, TOP2A

52 n present in acute Kawasaki disease ciliated bronchial epithelium and in a subset of macrophages in a

53 ene protein, is uniformly found in the human bronchial epithelium and in non-small cell lung carcinom

54 enzymes were significantly increased in the bronchial epithelium and inflammatory immune cells infil

55 rom the interstitium of the lung, across the bronchial epithelium and into the airway lumen, is known

56 e a proinflammatory response in the non-COPD bronchial epithelium and phosphate does not cause endoge

57 We found that SOCS1 was increased in vivo in bronchial epithelium and related to asthma severity.

58 Increased numbers of eosinophils in the bronchial epithelium and subepithelium were confirmed hi

59 The numbers of cells within the bronchial epithelium and submucosa expressing mRNA for T

60 heterozygosity, at 9p and p16 methylation in bronchial epithelium and the prevalence for methylation

61 ons, immunomodulatory cross-talk between the bronchial epithelium and tissue-resident immune cells co

62 be expressed by lung Clara-like cells in the bronchial epithelium and to be up-regulated in cystic fi

63 demonstrate that ICAM-2 is expressed on the bronchial epithelium and, together with ICAM-1, has an e

64 en tissue samples: 25 normal lung, 29 normal bronchial epithelium, and 20 preinvasive and 36 invasive

65 -alpha (GRO-alpha) protein expression in the bronchial epithelium, and an accompanying trend toward a

66 DP2 is expressed by the bronchial epithelium, and its activation drives epitheli

67 o Sonic hedgehog-expressing (Shh-expressing) bronchial epithelium, and mesenchymal expression of Foxf

68 rferon-stimulated genes were detected in the bronchial epithelium, and significant modulation of the

69 ene is expressed in the normal thyroid, lung bronchial epithelium, and specific areas of the forebrai

70 n and motogen for both normal and neoplastic bronchial epithelium, and that expression of the HGF rec

71 sia of goblet cell, eosinophilic invasion to bronchial epithelium, and thickened basal membrane were

72 Bronchospasm compresses the bronchial epithelium, and this compressive stress has be

73 t overexpress PGI(2) synthase selectively in bronchial epithelium are protected against RSV-induced w

74 We conclude that CF and non-CF nasal and bronchial epithelium are transcriptionally distinct and

75 nergic receptor agonist (LABA) on GCM in the bronchial epithelium are unknown.

76 ked increases in PSSG reactivity both in the bronchial epithelium as well as in parenchymal regions.

77 B (a noncancer cell line derived from normal bronchial epithelium), as well as PC3 (prostate cancer)

78 We observed IFN-alpha/beta deficiency in the bronchial epithelium at 3 time points in asthmatic patie

79 he lungs that was primarily localized to the bronchial epithelium at 4 h, but was present in a variet

80 d how age regulates RSV interaction with the bronchial epithelium barrier.

81 eased type III collagen deposition below the bronchial epithelium basement membrane, reminiscent of b

82 Rhinovirus (RV) infection of the bronchial epithelium (BE) is the main trigger of asthma

83 Treatment of human bronchial epithelium (BEAS-2B cells) with PGA1 induced n

84 or trigger of asthma exacerbations, with the bronchial epithelium being the major site of HRV infecti

85 However, deletion of GR in the bronchial epithelium blocked rhythmic CXCL5 production,

86 fferentially expressed between CF and non-CF bronchial epithelium but only 15 were differentially exp

87 Cyclin D1 was not expressed in normal bronchial epithelium but was detected in 7% of SMs, 15%

88 that T cells can migrate across a disrupted bronchial epithelium, but we provide evidence that egres

89 of allergen-induced NF-kappaB activation in bronchial epithelium by GSTM1 in human atopic asthmatics

90 The antigen detected in acute KD ciliated bronchial epithelium by IHC with synthetic KD antibodies

91 inetics of the novel H5Nx viruses in a human bronchial epithelium cell line, Calu-3.

92 eatment was detected in primary normal human bronchial epithelium cells.

93 l data and experimental studies suggest that bronchial epithelium could serve as a portal of entry fo

94 Surgical lung tissue and primary bronchial epithelium (cultured in air-liquid interface,

95 -CoV-2 infected differentiated primary human bronchial epithelium cultures for up to 12 days.

96 elevance of air-liquid interface cultures of bronchial epithelium derived from endobronchial biopsy s

97 evels of inflammatory mediator production in bronchial epithelium during the pathogenesis of inflamma

98 er, mir-218 expression is reduced in primary bronchial epithelium exposed to cigarette smoke condensa

99 The bronchial epithelium expressed DP2, but its expression w

100 The bronchial epithelium facilitates this remodeling process

101 arker gene expression did not persist in the bronchial epithelium following adeno-associated virus (A

102 e show that early induction of IL17 from the bronchial epithelium, following pathogenic encounter is

103 (up to 1.4 microns in diameter) in ciliated bronchial epithelium from 4 patients with acute KD exami

104 transversion in codon 245 was identified in bronchial epithelium from 7 of 10 sites in both lungs.

105 subjects with asthma and healthy controls in bronchial epithelium from biopsies (n = 27 versus n = 9)

106 p16 and DAP kinase was seen as frequently in bronchial epithelium from current smokers as from former

107 Ex vivo cultures of fully differentiated bronchial epithelium from endobronchial biopsy specimens

108 , but quitting promotes replenishment of the bronchial epithelium from mitotically quiescent cells th

109 r methylation of these genes was detected in bronchial epithelium from never-smokers.

110 on bodies in acute Kawasaki disease ciliated bronchial epithelium has provided direction for future K

111 a number of genes that are expressed in the bronchial epithelium have been linked to asthma suscepti

112 yocardiocytes, vascular smooth muscle cells, bronchial epithelium, hepatocytes, thymocytes, plasma ce

113 ays containing 323 samples, including normal bronchial epithelium, hyperplasia, squamous metaplasia,

114 that GSTM1 modulates NF-kappaB activation in bronchial epithelium in atopic asthmatics.

115 ons are expressed similarly in the nasal and bronchial epithelium in CF, the consequences are differe

116 , the anti-viral and repair responses of the bronchial epithelium in children with severe therapy-res

117 We also compared nasal and bronchial epithelium in each group and identified differ

118 We conclude that denudation of bronchial epithelium in endobronchial biopsies from asth

119 racterizing the molecular alterations in the bronchial epithelium in high-risk smokers.

120 ified that GSDMB is highly expressed in lung bronchial epithelium in human asthma.

121 e myeloid cells and positivity for Ly6C/G on bronchial epithelium in influenza virus-infected mice.

122 To determine the effects of WS-23 on human bronchial epithelium in isolation of other chemicals, we

123 nduces a 127-fold increase in ORMDL3 mRNA in bronchial epithelium in WT mice, with lesser 15-fold inc

124 horcic (buccal and nasal) and intrathoracic (bronchial) epithelium in healthy current and never smoke

125 Overexpression of GSDMB in primary human bronchial epithelium increased expression of genes impor

126 city, whereas enforced SNORA42 expression in bronchial epitheliums increases cell growth and colony f

127 e antigen in acute Kawasaki disease ciliated bronchial epithelium indicate that the Kawasaki disease-

128 of cyclin D1 expression in the normal human bronchial epithelium, indicating an inverse relationship

129 The overexpression of SPRR1B in bronchial epithelium is a marker for early metaplastic c

130 w that egression of human T cells across the bronchial epithelium is a multistep process, driven in p

131 These results show that activated bronchial epithelium is an important source of IP-10, Mi

132 Bronchial epithelium is considered a key player in coord

133 The bronchial epithelium is continuously exposed to a multit

134 pIgR immunostaining in the bronchial epithelium is decreased in severe COPD.

135 abnormalities in both NSCLC and premalignant bronchial epithelium is increase in chromosomal copy num

136 kin (IL)-33 genes in asthma, but its role in bronchial epithelium is unclear.

137 l expressed in alveolar, tracheal, and upper bronchial epithelium, is significantly down-regulated du

138 Normal cells including bronchial epithelium, lung, and trachea expressed wild-t

139 mall amounts of TGF-beta were present in the bronchial epithelium, macrophages, bronchial and vascula

140 ry cells sparsely distributed throughout the bronchial epithelium, many in innervated clusters of 20-

141 These results suggest that the bronchial epithelium may serve as an additional site of

142 ohistochemical expression patterns in normal bronchial epithelium (n = 36), squamous metaplasia (SM;

143 cells derived from human adenoids, and human bronchial epithelium (NHBE cells).

144 ir-liquid interface cultures of normal human bronchial epithelium (NHBE) exhibiting mucociliary activ

145 To determine whether the denudation of the bronchial epithelium observed in endobronchial biopsies

146 The correlation between p16 status in the bronchial epithelium obtained from lung lobes that did n

147 In addition, we analyzed brushes from the bronchial epithelium of 35 heavy smokers without cancer.

148 able to safely and effectively transfect the bronchial epithelium of foals using naked mRNA (i.e., mR

149 of miR-145, miR-223, and miR-494 in vivo in bronchial epithelium of individuals carrying the DeltaF5

150 odies (ICI) have been identified in ciliated bronchial epithelium of Kawasaki disease (KD) patients u

151 extent, DAP kinase, occurs frequently in the bronchial epithelium of lung cancer cases and cancer-fre

152 Conditional Map2k4 inactivation in the bronchial epithelium of mice had no discernible effect a

153 a genetic approach to inactivate Pten in the bronchial epithelium of mice.

154 tify and investigate the role of PSCs in the bronchial epithelium of neonatal mice, we developed an e

155 viously characterized gene expression in the bronchial epithelium of never smokers and identified the

156 cantly increased in both alveolar tissue and bronchial epithelium of patients with diabetes compared

157 nt protein-3 was found to be elevated in the bronchial epithelium of these mice, which may have impor

158 Inclusion bodies were not present in control bronchial epithelium or in nonciliated cells.

159 reinvasive lesion sites and elsewhere in the bronchial epithelium or lung parenchyma.

160 However, during transformation of the bronchial epithelium, overexpression of these species oc

161 In asthma, bronchial epithelium protein expression of ST2 is decrea

162 PD correlates with disease severity, and the bronchial epithelium reconstituted in vitro from these p

163 Ormdl3 transcript levels specifically in the bronchial epithelium resulted in reinstatement of suscep

164 Concurrent activation of TLR2 and IL17R in bronchial epithelium results in the sequestration of MyD

165 and RSV coinfection in primary cells of the bronchial epithelium results in viral proteins from both

166 neuroendocrine/neurosensory cells within the bronchial epithelium, revealing a targeted mode of cell

167 uired to form a morphologically recognizable bronchial epithelium, revealing an in vivo, cell type-sp

168 other inflammasome sensors tested in brushed bronchial epithelium samples from asthma patients and co

169 d gene expression in CF and non-CF nasal and bronchial epithelium samples using Illumina HumanRef-8 E

170 In contrast, adult bronchial epithelium showed no barrier damage and limite

171 opsy samples and promotes oncogenesis in the bronchial epithelium, suggesting that strategies to inhi

172 rotein expressed in airway smooth muscle and bronchial epithelium that regulates the activity of G-pr

173 imensional primary cell cultures from infant bronchial epithelium that reproduce several hallmarks of

174 The ability of the bronchial epithelium to control the balance of inhibitor

175 cular density as well as the contribution of bronchial epithelium to produce vascular endothelial gro

176 ould be important for early responses of the bronchial epithelium to Th2-stimuli.

177 unction and the pro-inflammatory response of bronchial epithelium upon HDM exposure and may thus have

178 nchi, we examined paraffin-embedded ciliated bronchial epithelium using light microscopy (LM) and tra

179 rylation-induced degradation and targeted to bronchial epithelium using the CC10 promoter.

180 Squamous metaplasia of the bronchial epithelium was increased in asthmatic patients

181 dition, PCNA immunostaining of the primitive bronchial epithelium was increased in the presence of TG

182 The most enriched pathway in CF bronchial epithelium was inflammatory response, whereas

183 iency of transduction in the balloon-treated bronchial epithelium was low but reached 20% in some are

184 binding to a cytoplasmic antigen in proximal bronchial epithelium was observed in 10 of 13 patients w

185 Loss of CS transcriptional responses within bronchial epithelium was related to impaired lung functi

186 Allergen-provoked NF-kappaB induction in bronchial epithelium was significantly greater in GSTM1+

187 Acute KD bronchial epithelium was subjected to immunofluorescence

188 Although the bronchial epithelium was well preserved throughout culti

189 and increased localization to the asthmatic bronchial epithelium, we investigated whether HRV infect

190 xpression of miR-629-3p was localized in the bronchial epithelium, whereas miR-223-3p and miR-142-3p

191 e development of precancerous lesions in the bronchial epithelium, which are precursors of lung squam

192 r absence of a three-gene "Th2 signature" in bronchial epithelium, which differ in terms of eosinophi

193 The specific tissue modeled is the human bronchial epithelium, which is of particular interest, a

194 tion to TGF-beta-driven reprogramming of the bronchial epithelium, which results in impaired lung IgA

195 I67, and NEK2) were upregulated in asthmatic bronchial epithelium while (GPRC5A and KRT8) were upregu

196 hma where their numbers are increased in the bronchial epithelium with increasing disease severity.

197 way contributing to IL-8 secretion in the CF bronchial epithelium with KL functioning as an endocrine