ライフサイエンスコーパス: budding

1 cation, and two inhibit virion formation and budding.

2 on, endosomal vesicle trafficking, and viral budding.

3 r1-dependent internal polarity cues used for budding.

4 hich is sufficient to demarcate sites for LD budding.

5 ulted in defects in ascospore morphology and budding.

6 in 1 (XPO1), is crucial for RSV assembly and budding.

7 cytokinesis, receptor degradation, and virus budding.

8 binding of host cell proteins and facilitate budding.

9 rgo selection and intralumenal vesicle (ILV) budding.

10 termine the prognostic significance of tumor budding.

11 ikely because of stalling of insulin-granule budding.

12 ene expression, as well as morphogenesis and budding.

13 in an unusual process, described as internal budding.

14 1R in actin-mediated clathrin-coated vesicle budding.

15 virus receptor binding, endosomal fusion, or budding.

16 and translation, as well as deficient viral budding.

17 onal selective phenotype of nuclear membrane budding.

18 forming in-depth analysis of plasma membrane budding, a cellular process that has previously been dis

19 nflammatory infiltrate, stromal content, and budding activity [BA] [potentially indicating epithelial

20 Ps for the evaluation of mechanisms of viral budding and entry as well as assessment of drug inhibito

21 Fat4(-/-) kidneys revealed abnormal ureteric budding and excessive RET signaling.

22 Ribonucleotide maps from both the budding and fission yeast reveal conservation of these p

23 Here we demonstrate, in both budding and fission yeast, that kinetochores and KNL1(Sp

24 erived from mitochondrial and nuclear DNA of budding and fission yeast.

25 Cell cycle mutants in the budding and fission yeasts have played critical roles in

26 mportant biological functions, such as viral budding and lipid-protein interactions.

27 In Saccharomyces cerevisiae, budding and mating projection (MP) formation use an over

28 e E2 juxtamembrane D-loop in mediating virus budding and particle production.

29 ESCRT machinery plays pivotal role in HIV-1 budding and release.

30 e first time the relationship between tumour budding and survival evaluated in patients with muscle i

31 during late stages of Gag assembly and HIV-1 budding and templates ESCRT-III assembly for membrane sc

32 tacks likely affects dynamic control of COPI budding and vesicle fusion at the rims.

33 Hantavirus assembly and budding are governed by the surface glycoproteins Gn and

34 nes required for immature rotavirus particle budding are not an extension of the ER but are COPII-der

35 ed cells stimulated with PMA, and upon viral budding, ASP becomes a structural protein of the HIV-1 e

36 les at the plasma membrane and drives virion budding, assisted by the cellular endosomal complex requ

37 molecular heterogeneity, and are created by budding at both plasma and endosome membranes.

38 that normally prevents repolarization and re-budding at CRMs.

39 erized in yeast, where they regulate vesicle budding at the trans-Golgi network.

40 We hypothesize that during nuclear budding, binding of UL25 situated at the pentagonal caps

41 MAT2) does not sort directly onto SGs during budding, but rather exit the TGN into nonregulated vesic

42 mic vs. viral nucleocapsids demonstrate that budding causes discrete changes in Cp-gRNA interactions.

43 regions of interest, micro tumor structure, budding, cell proliferation and tumor lymph vessels were

44 For example, small budding cells use very different strategies to dissemina

45 c master regulator), the absence of membrane budding correlates with failure of in vivo platelet prod

46 ilitate ILV formation: Upstream ESCRT-driven budding does not require ATP consumption as only a small

47 ge-scale viral processes including assembly, budding, egress, entry, and fusion.

48 ry mesenchyme that immediately surrounds the budding epithelium.

49 In this primer, we review the budding field of motion capture with deep learning.

50 We then discuss the budding field of precision fMRI and findings garnered fr

51 Vesicle budding for Golgi-to-plasma membrane trafficking is a ke

52 The TGN is disrupted and vesicle budding from Golgi cisternae is reduced in the tno1 muta

53 only viral component required for retroviral budding from infected cells.

54 dicted to be required, by analogy to vesicle budding from other membranes.

55 m producer cell plasma membranes, suggesting budding from specialized membrane microdomains.

56 -1 dissemination in BM: (i) semi-synchronous budding from T-cell and macrophage membranes, (ii) matur

57 ly acting endosomal factor involved in HIV-1 budding from the cells.

58 1 (HIV-1) acquires its lipid envelope during budding from the plasma membrane of the host cell.

59 localization of SG cargoes immediately after budding from the TGN revealed that, surprisingly, the bu

60 Previous work reported Gag budding from yeast spheroplasts, but Gag release was ESC

61 ned by varying the relative rates of vesicle budding, fusion and biochemical conversion.

62 rimers are confined to subviral regions of a budding Gag lattice, supporting a model where direct int

63 Tumour budding has been described as an independent prognostic

64 n cellular protein that is incorporated into budding HIV-1 particles and reduces HIV-1 infectivity by

65 ntivirus-host interactions involved in virus budding.IMPORTANCE FIV is a nonprimate lentivirus that i

66 With the discovery of lateral budding in 'Kolteria novifilia' and the capability of th

67 imulates proliferation in crypts and induces budding in organoids, in part through elevated and susta

68 Here, we deepen our understanding of prazole budding inhibition by studying a range of viruses in the

69 Viral budding is essential in the HIV-1 life cycle and mainly

70 and how curved coats are generated to enable budding is yet unclear.

71 racts with the immature particles to trigger budding, is synthesized as an ER transmembrane protein.

72 (neuro-)endocrine cells, we now quantify TGN budding kinetics of constitutive and regulated secretory

73 ic membrane-derived cholesterol, we observed budding lipid membranes elongating into the cytosol and/

74 cells poorly engages the virus packaging and budding machinery and do not effectively produce viral p

75 tural maps, supporting that ciliary vesicles budding may serve as ectosomes for cell-cell communicati

76 provide compelling support for the proposed budding mechanism, where each nascent betaOMP forms a hy

77 cle coat and progress on understanding COPII budding mechanisms are considered.

78 reduce the virus's ability to accumulate at budding microdomains and the VS.

79 cellular machinery that coats the inside of budding necks to perform membrane-modeling events necess

80 ce that the rotavirus maturation process of "budding" occurs through autophagy-hijacked COPII vesicle

81 ompared with the Brownian simulations of the budding of enveloped viruses.

82 P egress and that Amot co-expression rescues budding of eVP40 VLPs in a dose-dependent and PPxY-depen

83 When expressed alone, VP40 induces budding of filamentous virus-like particles, suggesting

84 lar protein Alix is sufficient to rescue the budding of FIV mutants devoid of canonical L-domains.

85 l-free assay to recapitulate COPII-dependent budding of large lipoprotein cargoes from the ER.

86 The budding of LDs requires extensive ER-LD crosstalk, but h

87 We found that FABP5 promotes the budding of particles ~150 nm in diameter and modulates t

88 al RNA with C protein into nucleocapsid, and budding of prM and E proteins into virions.

89 Calculations demonstrate that the budding of reverse micelles formed from interfacial Sr(I

90 s to have direct biological relevance during budding of the nascent influenza virus, which does not u

91 Vs), a main type of EVs generated by outward budding of the plasma membrane.

92 In the secretory pathway, budding of vesicular transport carriers from the trans-G

93 that is activated during, or shortly after, budding of viral particles from the surface of infected

94 ix protein (eVP40) orchestrates assembly and budding of virions in part by hijacking select WW-domain

95 owth by impairing late steps in the assembly/budding of virus particles at the plasma membrane.

96 inform our understanding of the morphology, budding order, and colony organization in the mature spe

97 physalis larvae, especially descriptions of budding order, were often framed with the mature colony

98 bud-site selection protein 13) regulates the budding pattern and pre-mRNA splicing in yeast cells; ho

99 -1 release, but how ESCRTs contribute to the budding process and how their activity is coordinated wi

100 stically divergent ESCRT-mediated lentivirus budding process in general, and to the role of Alix in p

101 In many cases, the budding process stalls prior to the release of the virus

102 talling is to be found in the physics of the budding process.

103 Our findings demonstrate that tumour budding, quantified using automated image analysis provi

104 Accordingly, we propose that membrane budding, rather than proplatelet formation, supplies the

105 Our studies demonstrate that membrane budding results in the sustained release of platelets di

106 The HBV budding site has been reported to be the ER or MVB, but

107 from their site of synthesis, the ER, to the budding site remain poorly understood.

108 (CG) simulations of ESCRT assembly at HIV-1 budding sites suggest that formation of a 12-membered ri

109 membrane and recruiting nucleocapsids to the budding sites.

110 ed yeast-like cells, with single or multiple budding, sometimes proliferating to form short, branchin

111 ispensable for Alix-mediated rescue of virus budding, suggesting the involvement of other regions of

112 potential energy barrier develops during the budding that must be overcome by capsid proteins diffusi

113 as well as their ability to undergo amitotic budding to escape dormancy.

114 d body plan, primarily multiplying through a budding type of asexual reproduction.

115 BUB-related 1 (BubR1) encoded by Budding Uninhibited by Benzimidazole 1B (BUB1B) is a cru

116 containing filopodial protrusions possessing budding viral particles.

117 role in assembling the different vRNPs into budding virions(1-8) and in directing reassortment betwe

118 ses HIV-1 infectivity when incorporated into budding virions.

119 ight become incorporated in the membranes of budding virions.

120 early-acting ESCRT-I within the head of the budding virus.

121 Furthermore, tumour budding was found to be correlated to TNM (p = 0.00089)

122 our decision tree model reported that tumour budding was the most significant feature (HR = 2.59, p =

123 clade to divide by binary fission as well as budding, we identified previously unknown modes of bacte

124 he intracellular membranes used for particle budding were thought to be endoplasmic reticulum (ER) be

125 ling of the basement membrane promote tumour budding, while stiffening of the basement membrane promo

126 Here, we show that 'axis core proteins' from budding yeast (Red1), mammals (SYCP2/SYCP3), and plants

127 CCS1, the budding yeast (S. cerevisiae) Cu chaperone for Cu-zinc (

128 -dimensional structure of pericentromeres in budding yeast (Saccharomyces cerevisiae) and establish t

129 n TMEM165 by heterologously expressing it in budding yeast (Saccharomyces cerevisiae) and in the bact

130 The lysosomal vacuole of budding yeast (Saccharomyces cerevisiae) has served as a

131 The Mag1 and Tpa1 proteins from budding yeast (Saccharomyces cerevisiae) have both been

132 active subunit Rrp44/Dis3 of the exosome in budding yeast (Saccharomyces cerevisiae) is considered a

133 The yeast vacuolar H(+)-ATPase (V-ATPase) of budding yeast (Saccharomyces cerevisiae) is regulated by

134 gated the selectivity and sensitivity of the budding yeast (Saccharomyces cerevisiae) multidrug respo

135 Budding yeast (Saccharomyces cerevisiae) responds to low

136 Here, we used budding yeast (Saccharomyces cerevisiae) to explore how

137 In budding yeast (Saccharomyces cerevisiae), EVs function a

138 K-PPn was originally discovered in budding yeast (Saccharomyces cerevisiae), in which polyP

139 of pantothenic acid for CoA biosynthesis in budding yeast (Saccharomyces cerevisiae), significantly

140 In budding yeast (Saccharomyces cerevisiae), the essential

141 Here, using budding yeast (Saccharomyces cerevisiae), we established

142 otein complex replication protein A (RPA) in budding yeast (Saccharomyces cerevisiae).

143 oduced dUTP/5-FdUTP-mediated DNA toxicity in budding yeast (Saccharomyces cerevisiae).

144 tages, we developed a method for scRNAseq in budding yeast (Saccharomyces cerevisiae).

145 rated analogous R402C and R402H mutations in budding yeast alpha-tubulin, which exhibit a simplified

146 chanism for dosage compensation in aneuploid budding yeast and human cell lines.

147 Both budding yeast and human tumor cells utilize members of a

148 g kinases, delineating the key substrates in budding yeast and humans.

149 ncreased genomic instability during aging in budding yeast and identify striking age-associated genom

150 e modeled pathogenic EXOSC5 variants in both budding yeast and mammalian cells.

151 and exchange during meiotic recombination in budding yeast and many other organisms including humans.

152 ible DNA at almost all genomic AluI sites in budding yeast and mouse liver nuclei.

153 Here we show that growing budding yeast and primary mammalian cells beyond a certa

154 tional signature of redox stress in ssDNA of budding yeast and the signature of aging in human mitoch

155 Using the budding yeast Ase1, we identify unique contributions for

156 pr) inserted into the silenced chromosome in budding yeast can overcome Sir2-dependent silencing upon

157 Budding yeast can produce ATP from carbon sources by mec

158 a gradient in tension over multiple isogenic budding yeast cell lines by genetically altering the mag

159 EMBO Journal, Stahl et al (2019) reveal that budding yeast cells confer a growth advantage to their d

160 increased cell death caused by DNA damage in budding yeast cells lacking the Rad53 checkpoint protein

161 We conclude that aneuploid budding yeast cells mount the ESR, rather than the CAGE

162 e fluorescence microscopy techniques in live budding yeast cells to investigate how Mex67 facilitates

163 The gene that allows budding yeast cells to switch their mating type evolved

164 Budding yeast centromeres comprise three sequential "cen

165 Recent breakthroughs with synthetic budding yeast chromosomes expedite the creation of synth

166 The mating of budding yeast depends on chemotropism, a fundamental cel

167 hesin loader, whose presence on chromatin in budding yeast depends on the RSC chromatin remodeling co

168 The localization of Ipl1 to kinetochores in budding yeast depends upon multiple pathways, including

169 ior requires the microtubule regulator Stu2 (budding yeast Dis1/XMAP215 ortholog), which we demonstra

170 Budding yeast divide asymmetrically and HO is expressed

171 Using the reconstituted budding yeast DNA replication system, we find that the f

172 Our findings indicate that size control in budding yeast does not fundamentally originate from the

173 In this work, we show that budding yeast executes meiotically programmed mitochondr

174 A newly characterized group of budding yeast found in fermented milk drinks in West and

175 Here, we have reconstituted budding yeast Hsf1-Hsp70 activation complexes and find t

176 Here, we find that involvement of the budding yeast Hsp70 chaperones Ssa1 and Ssa2 in nuclear

177 our assay robustly detects small changes in budding yeast initiation kinetics, which could not be re

178 nto the first gap phase of the cell cycle in budding yeast is controlled by the Mitotic Exit Network

179 Here, we show that key functions of budding yeast Kinesin-14 Cik1-Kar3 are accomplished in a

180 ored the potential for autophagy to regulate budding yeast meiosis.

181 tial partitioning of nucleolar components in budding yeast mitosis.

182 examine the DDC, induced by DNA DSBs, in the budding yeast model system and in mammals.

183 Here, we uncover a mechanism by which budding yeast modulate viscosity in response to temperat

184 Fission yeast Mso1 shares homology with budding yeast Mso1 and human Mint1, proteins that intera

185 ears ago, the first isolation of conditional budding yeast mutants that were defective in cell divisi

186 tly image and quantitate these dynamics in a budding yeast nuclear extract that reconstitutes activat

187 he consequences to the size and shape of the budding yeast nucleus when cell expansion is inhibited b

188 Here we show the existence in budding yeast of a common aneuploidy gene-expression sig

189 Here, we show that Mph1, the budding yeast ortholog of Fanconi anemia helicase FANCM,

190 fission yeast or a single ring of NPFs as in budding yeast produce enough force to elongate the invag

191 reconstituting these processes with purified budding yeast proteins, we show that ubiquitylation is t

192 The Mitotic Exit Network (MEN), a budding yeast Ras-like signal transduction cascade, tran

193 cative DNA helicase, CMG, demonstrating that budding yeast replisomes lack intrinsic mechanisms that

194 Using reconstituted budding yeast replisomes, we show that mutational inacti

195 Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin

196 Modeling the dysregulation in budding yeast resulted in disrupted structural integrity

197 protein that is structurally related to the budding yeast Rtt107 and human PTIP DNA damage response

198 start sites (TSSs) has been identified in a budding yeast Saccharomyces cerevisiae ("scanning model"

199 utational effects for gene expression in the budding yeast Saccharomyces cerevisiae by measuring the

200 The budding yeast Saccharomyces cerevisiae divides asymmetri

201 ry mechanisms in model organisms such as the budding yeast Saccharomyces cerevisiae Gpa2 is a yeast G

202 Genetic screening in the budding yeast Saccharomyces cerevisiae has isolated seve

203 Features of this regulatory circuit in the budding yeast Saccharomyces cerevisiae have been recentl

204 c view of the eukaryal cell cycle, using the budding yeast Saccharomyces cerevisiae Protein synthesis

205 alyzed separation of function mutants in the budding yeast Saccharomyces cerevisiae that allow global

206 -wide fluorescence microscopy studies in the budding yeast Saccharomyces cerevisiae to identify a pro

207 genetic instability in diploid cells of the budding yeast Saccharomyces cerevisiae, and have isolate

208 analyses, we show that DDR activation in the budding yeast Saccharomyces cerevisiae, either by geneti

209 In the budding yeast Saccharomyces cerevisiae, nearly all H2A i

210 In the budding yeast Saccharomyces cerevisiae, the five mitotic

211 In the budding yeast Saccharomyces cerevisiae, we demonstrate t

212 Here, using the budding yeast Saccharomyces cerevisiae, we report the di

213 -driven reaction cycle of condensin from the budding yeast Saccharomyces cerevisiae.

214 tructed by cloning the centromere DNA of the budding yeast Saccharomyces cerevisiae.

215 on in G1/S transcriptional regulation in the budding yeast Saccharomyces cerevisiae.

216 d53 to distinct replication complexes in the budding yeast Saccharomyces cerevisiae.

217 sm on the variabilities in cell cycle of the budding yeast Saccharomyces cerevisiae.

218 The budding yeast SCF(Met30) complex is an essential cullin-

219 Budding yeast SER3 is repressed under serine-replete con

220 that a Rad51 paralog-containing complex, the budding yeast Shu complex, directly recognizes and enabl

221 Here we purified the budding yeast Smc5/6 holocomplex and characterized its c

222 rred the mating compatibility systems of 332 budding yeast species from their genome sequences.

223 n (iHyPr) to combine the genomes of multiple budding yeast species, generating Saccharomyces allopoly

224 f multiple kinases by the meiosis-I-specific budding yeast Spo13 protein.

225 elatives of Escherichia coli into a group of budding yeast taxa.

226 A strain of budding yeast that contains one large chromosome reveals

227 Here, using proteomics-based approaches in budding yeast to analyze the effects of Nop53 on the exo

228 Using budding yeast to gain temporal and genetic traction on c

229 Budding yeast treated with hydroxyurea (HU) activate the

230 We show that budding yeast Ty3/Gypsy co-opts binding sites of the ess

231 and the scope of RNA-based regulation in the budding yeast UPR and have implications for the control

232 During the budding yeast UPR, Ire1 excises an intron from the HAC1

233 The budding yeast v-SNARE, Snc1, mediates fusion of exocytic

234 rom IMR90 (human lung fibroblast), and (iii) budding yeast whole-genome Hi-C data at a single restric

235 nced toolbox of cell cycle tag constructs in budding yeast with defined and compatible peak expressio

236 In budding yeast, a conserved signaling network surrounding

237 In budding yeast, a specific growth site is selected in the

238 We investigated these questions in budding yeast, an organism found in diverse environments

239 to show that autoinhibition is conserved in budding yeast, and plays a key role in coordinating in v

240 h defined positions throughout the genome of budding yeast, as seen in mammalian cells.

241 In budding yeast, CDK substrates with Leu/Pro-rich (LP) doc

242 In budding yeast, cortical and cytoplasmic ER-phagy require

243 In budding yeast, cytokinetic actomyosin ring contraction a

244 Mammals, unlike budding yeast, depend on the histone H3 variant, CENP-A,

245 In budding yeast, end processing requires the helicase Sgs1

246 nal modeling of the full genome during G1 in budding yeast, exploring four decades of timescales for

247 ether the main histone acetyltransferases in budding yeast, Gcn5 and Esa1, possess crotonyltransferas

248 In budding yeast, histone H3 threonine 11 phosphorylation (

249 We addressed this question in budding yeast, in which cells enter meiosis when starved

250 In budding yeast, meiotic kinetochore remodeling is mediate

251 In budding yeast, mitochondria drive the assembly of the mi

252 In budding yeast, Saccharomyces cerevisiae, CR is commonly

253 We used the budding yeast, Saccharomyces cerevisiae, to investigate

254 We forced the budding yeast, Saccharomyces cerevisiae, to use the meio

255 g the hourglass-to-double-ring transition in budding yeast, septins acquire a "zonal architecture" in

256 he environment drive cell fate decisions. In budding yeast, the decision to enter meiosis is controll

257 In budding yeast, the myosin-V Myo2 is aided by the kinesin

258 In budding yeast, the retention of kinetochores on dynamic

259 Prior to anaphase of budding yeast, the ribosomal DNA (RDN) condenses to a th

260 In budding yeast, the transcription factors SBF and MBF act

261 In budding yeast, transcription within 20 kb of telomeres i

262 In aneuploid budding yeast, two opposing gene-expression patterns hav

263 In contrast to budding yeast, WASp-mediated actin nucleation plays an e

264 ion of two plant AMTs (AtAMT1;2 and AMT2) in budding yeast, we found that systematic replacements in

265 Here, using budding yeast, we identify a proteolytic pathway that co

266 To overcome these hurdles for budding yeast, we recently optimized an artificial fluor

267 Performing experiments in budding yeast, we show that our estimates of numbers agr

268 l dynamics during meiotic differentiation in budding yeast, we sought to understand how organelle mor

269 tion systems by using extracts prepared from budding yeast, wheat germ, and rabbit reticulocyte lysat

270 focus on recent systematic studies, many in budding yeast, which have revealed that large numbers of

271 Here we use budding yeast, which lack Torsins, to interrogate TorA f

272 In budding yeast, which possesses simple point centromeres,

273 s the centromeric base of the kinetochore in budding yeast.

274 at centromeric (CEN) chromatin in wild-type budding yeast.

275 biquitin chain required for damage bypass in budding yeast.

276 litates MutLgamma-dependent crossing over in budding yeast.

277 e first cell division cycle (CDC) mutants in budding yeast.

278 unction for MRX in limiting transcription in budding yeast.

279 p40, an essential RNA-splicing factor in the budding yeast.

280 nfluences both of these replication steps in budding yeast.

281 is orchestrated by the Atg1-Atg13 complex in budding yeast.

282 ents suggest that bet hedging has evolved in budding yeast.

283 to achieve proper timing of cell division in budding yeast.

284 hase axis length and S-phase progression, in budding yeast.

285 me bi-orientation, independently of Bir1, in budding yeast.

286 ry dynamics at high resolution in laboratory budding yeast.

287 tion initiation in the compact genome of the budding yeast.

288 he NPC and the mobile transport machinery in budding yeast.

289 emerging coding sequences impact fitness in budding yeast.

290 3' exoribonuclease, as a cofactor of RNAi in budding yeast.

291 ding intermediates prior to DNA insertion in budding yeast.

292 or the asymmetric cell shape and division of budding yeast.

293 To identify other factors that act in the budding-yeast pathway, we performed an unbiased genetic

294 romyces cerevisiae, RNAi is present in other budding-yeast species, including Naumovozyma castellii,

295 variation to uncover a novel means by which budding yeasts can overcome highly successful genetic pa

296 Compared to other budding yeasts in the subphylum Saccharomycotina, we not

297 s in Saccharomyces cerevisiae and some other budding yeasts, but most eukaryotes lack sequence-specif

298 revisiae had a single evolutionary origin in budding yeasts, simpler "flip/flop" mechanisms of switch

299 e split of Yarrowia lipolytica and the other budding yeasts.

300 nuclear parasites that have co-evolved with budding yeasts.