ライフサイエンスコーパス: by inhibiting

1 rphyrins through substrate reduction therapy by inhibiting 5-aminolevulinate synthase 2 (ALAS2), the

2 ound that miR-671-5p reduces LUSC metastasis by inhibiting a circular RNA (circRNA), CDR1as.

3 , i.e., the suppression of cancer metastasis by inhibiting a crucial protein-protein interaction invo

4 s to drive the differentiation of PC12 cells by inhibiting a nuclease that promotes RNA-induced silen

5 Fir1 protects cytokinesis in part by inhibiting a separation-specific exocytosis function

6 e conclusion that SPT-enol acts on nematodes by inhibiting ACC.

7 ins that stabilize actin filaments (F-actin) by inhibiting actin polymerization and depolymerization.

8 HIV-1 exerts broad immunosuppressive effects by inhibiting activation of the transcription factor NF-

9 forces, and this relationship can be shifted by inhibiting actomyosin contractility.

10 ne-induced toxicity, which could be mimicked by inhibiting adenosine deaminase in control lines.

11 erties of immune resistance that are reduced by inhibiting Akt-activated beta-catenin.

12 ing circulating IGF1, insulin and leptin and by inhibiting AKT-mTOR signalling via upregulation of EG

13 Subsequent reshaping of the glycome by inhibiting alpha-mannosidase I resulted in significan

14 ells may regulate periodontitis pathogenesis by inhibiting alveolar bone loss through directly blocki

15 cupoints following MO treatment were reduced by inhibiting AMPA and NMDA receptors in the spinal cord

16 t and synaptic depotentiation were disrupted by inhibiting AMPAR internalization via intra-NAc shell

17 By inhibiting and activating the de novo phospholipid bi

18 ownstream sequences into an ectopic S region by inhibiting and promoting their dynamic alignment with

19 L-18 production favors bacterial persistence by inhibiting antimicrobial peptide production and, at t

20 is mechanism also protects cancerous tissues by inhibiting antitumor immune cells in hypoxic and extr

21 where it represses effector-gene expression by inhibiting AP-1 function.

22 regulating latency and reactivation, in part by inhibiting apoptosis.

23 nergy when the proton-motive force collapses by inhibiting ATP hydrolysis.

24 d to be a potential target of cancer therapy by inhibiting Aurora B or survivin in different types of

25 helial cells, inhibits degradation of Kif19a by inhibiting autophagy, a cellular recycling mechanism

26 Stretch-induced apoptosis was attenuated by inhibiting autophagy.

27 events ISO-induced apoptosis of kidney cells by inhibiting Bax protein upregulation and caspase-3 act

28 roved chemotherapy and radiotherapy response by inhibiting BCSC self-renewal and associated pluripote

29 te that BBR antagonizes beta-catenin pathway by inhibiting beta-catenin translation and mTOR activity

30 ading suppresses tumor growth and osteolysis by inhibiting bone resorption and enhancing bone formati

31 presents a "two-pronged" anticancer strategy by inhibiting both critical growth-promoting cell signal

32 mpaired HCC progression in vitro and in vivo by inhibiting both tumor cell proliferation and migratio

33 regulates MYC levels directly and indirectly by inhibiting BRD4 kinase activity.

34 The protein, by inhibiting buffer crystallization, prevented the pH s

35 ow that C5aR2 is protective in intestinal IR by inhibiting C5aR1-mediated neutrophil recruitment to t

36 ) stores with cyclopiazonic acid and reduced by inhibiting Ca(2+) influx via Orai channels.

37 ICC-IM responses to EFS were ablated by inhibiting Ca(2+) stores with cyclopiazonic acid and

38 in acetylation and tumour cell proliferation by inhibiting calcineurin and NFATc3 activation in mouse

39 how MIPs themselves can act as therapeutics by inhibiting cancer growth.

40 ling IL-1alpha/beta release from neutrophils by inhibiting caspase-8-dependent apoptosis and Ripk1-Ri

41 orrelated with neuronal activity and blocked by inhibiting caspases in presynaptic neurons, implicati

42 t losartan can exert antimetastatic activity by inhibiting CCR2 signaling and suppressing monocyte re

43 ripotency, and this can be achieved in vitro by inhibiting CDK8/19 kinase activity.

44 Pom1 controls the timing of mitotic entry by inhibiting Cdr2, which forms stable membrane-associat

45 rs in mice were regressed after VP treatment by inhibiting cell cycle pathway proteins.

46 cytotoxic to human cholangiocarcinoma cells by inhibiting cell division and inducing apoptosis.

47 inhibited new nephron formation after injury by inhibiting cell proliferation, and resulted in loss o

48 reticulata blocks signaled active avoidance by inhibiting cells in the pedunculopontine tegmental nu

49 edunculopontine tegmental nucleus (PPT), not by inhibiting cells in the superior colliculus or thalam

50 ting that R-DPRs cause neurotoxicity in part by inhibiting cellular RNA surveillance.

51 In conclusion, increasing HDL-C levels by inhibiting CETP activity is associated with inhibitio

52 S256, and induces AQP2 membrane accumulation by inhibiting clathrin-mediated endocytosis and increasi

53 ediated degradation of the bonding interface by inhibiting collagenolytic activity.

54 such multisensory conflicts can be minimized by inhibiting core cortical areas of the subordinate sen

55 ibuprofen, and naproxen) block PG synthesis by inhibiting COX-1 and COX-2.

56 rategies to control Cr(VI) in drinking water by inhibiting Cr(0) reactivity.

57 f radiation, and blocks growth of HNSCC PDXs by inhibiting CSCs.

58 tor of cell proliferation and acts primarily by inhibiting cyclin-dependent kinases (CDKs).

59 , which can be prevented by applying Bmp2 or by inhibiting D cyclin activity.

60 own in MCF10A H-RAS(V12) breast cancer cells by inhibiting de novo proline biosynthesis and impairing

61 d interference with menaquinone biosynthesis by inhibiting demethylmenaquinone methyltransferase and

62 In contrast, netrin-1 promotes survival by inhibiting dependence receptors, including UNC5B, and

63 distinct viper venom bioactivities in vitro by inhibiting different enzymatic toxin families.

64 Potentiating radiotherapy and chemotherapy by inhibiting DNA damage repair is proposed as a therape

65 athway should further sensitize cancer cells by inhibiting DNA repair, thereby increasing the respons

66 spironolactone blocks EBV virion production by inhibiting EBV SM function.

67 bacterium Shigella flexneri stalls apoptosis by inhibiting effector caspase activity.

68 ommencing gene transcription that is reduced by inhibiting EGFR, down-regulating FUS, or expressing F

69 icate that the specific reduction of H3K9me2 by inhibiting EHMT1/2 during nuclear reprogramming impac

70 Glutamate secretion could be blocked by inhibiting either glutaminase or KV1.3 channels, whic

71 E decreases mitochondrial oxygen consumption by inhibiting electron transport chain complexes.

72 chiral nanowire structures can be suppressed by inhibiting electron transport in a helical way to dim

73 ation of NuMA1 stabilizes the developing AIS by inhibiting endocytosis and removal of AIS proteins.

74 uggests that TBC1D8B plays a regulatory role by inhibiting endogenous RAB11.

75 sine nucleotides, denoted as (p)ppGpp, which by inhibiting energy requiring molecular pathways help b

76 gatekeeper that responds to decreases in ATP by inhibiting energy-consuming anabolic processes and pr

77 e dichotomous functions of the two receptors by inhibiting ET(A)R with macitentan, an ET(A)R antagoni

78 s modulate neurotransmission presynaptically by inhibiting exocytosis.

79 3 blocked plasmid replication, respectively, by inhibiting expression or function of the plasmid repl

80 dation or synaptic reentry reinforcement, or by inhibiting extinction-memory consolidation.

81 cells and cellular migration were attenuated by inhibiting F. nucleatum host-cell binding and entry u

82 is to potentiate endocannabinoid signalling by inhibiting fatty acid amide hydrolase (FAAH), the enz

83 may be able to prevent anaphylaxis in humans by inhibiting FcepsilonRI-mediated signaling.

84 repare" pathways processing-predicted inputs by inhibiting feedforward gamma rhythms and associated s

85 tion of Cd under reducing condition possibly by inhibiting ferrihydrite transformation and recapturin

86 numbers are driving this decline, presumably by inhibiting fire spread.

87 and that GSK3beta suppresses tubular repair by inhibiting FoxM1.

88 venting virus membrane fusion with cells and by inhibiting fusion of infected cells (syncytialization

89 inal mTOR alone lowers plasma glucose levels by inhibiting glucose production in rodents with diabete

90 By inhibiting glucose reabsorption in the proximal tubul

91 were developed to lower blood glucose levels by inhibiting glucose reabsorption in the proximal tubul

92 g SLC2A1 (GLUT1) mRNA and protein levels and by inhibiting glucose transport.

93 esses and were mimicked in wild-type animals by inhibiting glutamate clearance.

94 and genetic landscape, and can be exploited by inhibiting glutathione peroxidase 4 (GPX4) with small

95 -induced ferroptosis but not in that induced by inhibiting glutathione peroxidase-4 (GPX4), the most

96 through the synthetic pathways was maximized by inhibiting glycolate export from the chloroplast.

97 ducing unfolded protein response rather than by inhibiting glycolysis.

98 nts dissemination of a gut-resident pathogen by inhibiting goblet cell-mediated bacterial translocati

99 Mechanistically, betaOHB acts by inhibiting HDACs to reinforce Notch signaling, instru

100 in C displays intriguing biological activity by inhibiting hepatitis C viral entry.

101 pendent and ligand-independent Met signaling by inhibiting HGF binding to Met and inducing receptor d

102 bility and lethality in BRCA1-deficient mice by inhibiting homologous recombination (HR).

103 modify animal host physiology, for example, by inhibiting host protein synthesis.

104 HSV-1 infection in an ICP0-dependent manner by inhibiting ICP0 E3 ligase activity.

105 uggest that IFN-gamma blocks VZV replication by inhibiting IE62 function in a cell line-dependent man

106 uggest that IFN-gamma blocks VZV replication by inhibiting IE62 function in a cell line-dependent man

107 b was exerting its beneficial effects in HLH by inhibiting IFN-gamma signaling or by targeting signal

108 spider Atrax robustus, induces pain in mice by inhibiting inactivation of voltage-gated sodium (Na(V

109 ig-I or Mda5 deficiency reduced HSPC numbers by inhibiting inflammatory signals that were in turn enh

110 the CD47-SIRPA axis suppresses phagocytosis by inhibiting inside-out activation of integrin signalin

111 bacteria, H-NS promotes the cellular fitness by inhibiting intragenic transcription from AT-rich targ

112 optosis during cold storage is best achieved by inhibiting intrinsic pathways.

113 ty of pathogen associated molecular patterns by inhibiting IRF3 and NF-kappaB nuclear transport.

114 ssory protein MRAP2 altered GHSR1a signaling by inhibiting its constitutive activity, as well as by e

115 target of anticancer and anti-obesity drugs by inhibiting its DNA-binding activities.

116 SUMOylation stabilizes BZR1 in the nucleus by inhibiting its interaction with BIN2 kinase.

117 Blockade of Ras activity by inhibiting its post-translational methylation catalyz

118 sion through regulation of its promoters and by inhibiting its presentation through interaction with

119 Ethylene acts as an inverse agonist by inhibiting its receptors, resulting in lower CTR1 act

120 OCS3 enhances the anti-inflammatory response by inhibiting JAK/STAT-signaling activation.

121 f PTPN22 at Ser(751) prolonged its half-life by inhibiting K48-linked ubiquitination and impairing re

122 TRADD modulates cellular homeostasis by inhibiting K63-linked ubiquitination of beclin 1 medi

123 sition of proteins proximal to KRAS, notably by inhibiting KRAS proximity to the SNARE vesicular tran

124 te Wnt targets including c-Myc and Cyclin D1 by inhibiting LEF transcriptional activity in GC cells.

125 TA exhibited dual effects by inhibiting lipogenic signaling and suppression of lip

126 ng activity of Delta(9)-tetrahydrocannabinol by inhibiting local autophagy.

127 ion of atherosclerosis induced periodontitis by inhibiting local, systemic and vascular inflammation,

128 We experimentally tested the model by inhibiting low dose infection with the drug tenofovir

129 l ligation and puncture (CLP)-induced sepsis by inhibiting lung inflammation, leukocyte apoptosis, an

130 way dysregulates degradation of Cx43, either by inhibiting lysosomal activity or suppressing the leve

131 that GRK2 can function as a tumor suppressor by inhibiting MALT1 and provide a roadmap for developing

132 HPV16E7 protein promotes MAP4 stability by inhibiting MAP4 phosphorylation- mediated degradation

133 yer that minimizes the generation of bubbles by inhibiting mass transport along a vertical direction.

134 reased omental metastasis at least partially by inhibiting MCP-1 secretion from adipocytes independen

135 ythrocyte hemolysis and antioxidant activity by inhibiting membrane lipid peroxidation.

136 EBV-miR-BART6-3p, acts as a tumor suppressor by inhibiting metastasis and invasion.

137 role in plant defense against phytopathogens by inhibiting microbial polygalacturonases (PGs).

138 t Rik-203 facilitates neural differentiation by inhibiting miR-101a-3p's ability to reduce GSK-3beta

139 lung tumor development and brain metastasis by inhibiting mitochondrial bioenergetics, stimulating t

140 causes toxicity by binding to hemoglobin and by inhibiting mitochondrial cytochrome c oxidase (CcO),

141 lestatic liver promotes BA-induced pathology by inhibiting MLL4 expression.

142 consistent with AimB promoting MreB dynamics by inhibiting monomer-monomer assembly interactions, rep

143 activity suppresses myoblast differentiation by inhibiting MyoD and MEF2c expression.

144 y depolymerizing actin with latrunculin A or by inhibiting myosin II with blebbistatin).

145 er, impaired the maturation of NLGN4 protein by inhibiting N-linked glycosylation at an adjacent resi

146 e that is polymorphic in humans, is reversed by inhibiting necroptosis.

147 aired synaptic plasticity, which was blocked by inhibiting neural lactate uptake.

148 ildren affected by Dravet syndrome, possibly by inhibiting neuronal lactate dehydrogenase 5 isoenzyme

149 Its primary role is to protect lung tissue by inhibiting neutrophil elastase.

150 therapeutic benefits of LCD NP are achieved by inhibiting neutrophil-mediated inflammatory macrophag

151 So A49 promotes virulence by inhibiting NF-kappaB activation and by another mechan

152 LPS activated murine macrophages (RAW 264.7) by inhibiting NF-kappaB activation and its nuclear trans

153 ecific adhesion properties to hSFs, reversed by inhibiting NF-kB translocation to the nucleus.

154 the balance of short and long 3'UTR isoforms by inhibiting NMD, in addition to its previously describ

155 ing that ethanol suppresses their activation by inhibiting norepinephrine release.

156 that C-B and C-I inhibit colon cancer growth by inhibiting Notch signaling pathway.

157 t not neurons, and this ability was reversed by inhibiting NQO1.

158 s to suppress dendritic microtubule dynamics by inhibiting nucleation.

159 Blocking adenosine production by inhibiting nucleotide-metabolizing enzymes, such as e

160 UDCA may protect the fetus in ICP by inhibiting OATP4A1-mediated bile acid transfer and TC

161 s to the OB impede early olfactory signaling by inhibiting OB output neurons, thereby dynamically gat

162 ocytotic pathway of SGLT1 at the trans-Golgi by inhibiting ODC.

163 n induced by prolonged calcifying conditions by inhibiting osteogenic differentiation and increases i

164 ypothesis that SOD3 preserves HA homeostasis by inhibiting oxidative and enzymatic hyaluronidase-medi

165 ting in Ach resistance that could be rescued by inhibiting p38 MAPK.

166 2 promotes breast cancer early dissemination by inhibiting p38, but the downstream pathway in this pr

167 new strategy to restore anti-tumor immunity by inhibiting pathways of force-generation.

168 f statins as tuberculosis preventive therapy by inhibiting PDIM spread.

169 table secreted proteins can also be affected by inhibiting PERK.

170 Citrate is known to suppress glycolysis by inhibiting phosphofructokinase-1 and activate glucone

171 activate the unfolded protein response (UPR) by inhibiting phosphoglucomutase activity and causing th

172 The 5-HT(2A) -induced Q pathway was restored by inhibiting PKA activity (Rp-8-Br-cAMPS).

173 Aspirin prevents thrombosis by inhibiting platelet cyclooxygenase (COX)-1 activity a

174 gger oligodendrogenesis from precursor cells by inhibiting platelet-derived growth factor receptor-al

175 It does so by inhibiting primary root extension and stimulating lat

176 alignant transformation of predisposed cells by inhibiting pro-apoptotic signals and activating tumor

177 st that S100A8 and S100A9 regulate psoriasis by inhibiting production of IL-17A and -F, thereby, to o

178 ls (Tregs) facilitate TB disease progression by inhibiting protective Th1 and Th17 responses.

179 lasts expressing progerin, but were restored by inhibiting protein farnesylation.

180 While most drugs act by inhibiting protein function upon target binding, we f

181 d drives aerobic glycolysis and tumor growth by inhibiting pyruvate kinase M2 (PKM2).

182 ownstream target of WNT5B, which was blocked by inhibiting RAC1, a prominent regulator of C-JUN activ

183 TRAF3 limits bone destruction by inhibiting RANKL-induced NF-kappaB signaling in osteo

184 s by counteracting MYC-induced apoptosis and by inhibiting RB1 function, thereby promoting cell-cycle

185 ogen-induced spine elimination was prevented by inhibiting reactive oxygen species (ROS) generation o

186 AMPK's ability to maintain redox homeostasis by inhibiting reactive oxygen species production and mai

187 cells reduced the level of MMP-1 expression by inhibiting recruitment of NF-kappaB to the MMP-1 prom

188 s negative feedback over apoptotic signaling by inhibiting recruitment of the key proapoptotic protei

189 trolyte balance and blood pressure, in part, by inhibiting renal sodium transport.

190 , our data revealed that SPARC promoted GSIS by inhibiting RGS4 in pancreatic beta cells.

191 PS1/gamma-secretase mediates axon growth by inhibiting RhoA signaling and cleaving EphA3 independ

192 Parkin axis negatively regulates necroptosis by inhibiting RIPK1-RIPK3 complex formation; this regula

193 es to improve axonal regeneration, including by inhibiting ROCK, should be further explored.

194 ular levels of reactive oxygen species (ROS) by inhibiting ROS scavenging.

195 mito-TEMPO blocked the induction of IL-1beta by inhibiting ROS with SAA treatment.

196 utic to block pathological axon degeneration by inhibiting SARM1, an approach that may be applied cli

197 sponse and induction of immunological memory by inhibiting secondary tumor growth upon re-challenge w

198 By inhibiting seed germination and post-germinative grow

199 not monomeric, beta-arrestin2 increases tau by inhibiting self-interaction of the autophagy cargo re

200 e de novo synthesis pathway of sphingolipids by inhibiting serine palmitoyl transferase in response t

201 ants target the serotonin transporter (SERT) by inhibiting serotonin reuptake.

202 kinase-c-Jun signaling and drives senescence by inhibiting sirtuin-1.

203 ytocin may modulate MSMC electrical activity by inhibiting SLO2.1 potassium channels.

204 Shh, we found that CBs reduced Shh signaling by inhibiting Smoothened (Smo), while Shh mRNA or a CB1

205 nent [Ca(2+)]cyt spikes that were attenuated by inhibiting SOCE, underlining the relevance of these [

206 re to MIS during the first six days of life, by inhibiting specification of the stroma, dysregulates

207 a signaling, also blocked IFN-beta responses by inhibiting STAT1/STAT2-mediated transcription in infe

208 aled that BMP10 suppressed tumor cell growth by inhibiting STAT3 signaling.

209 protrusions could be effectively suppressed by inhibiting subcellular mitochondrial trafficking.

210 to possess blood glucose lowering properties by inhibiting sugar transporters in the small intestine

211 of RAGE blocks the effects of IL-13 and IL-4 by inhibiting sustained STAT6 activation and downstream

212 in sensory nerves to regulate bone formation by inhibiting sympathetic activity through the central n

213 BHB exerts its anxiolytic effects, possibly by inhibiting systemic TNF-alpha.

214 at filgotinib suppresses HIV-1 transcription by inhibiting T cell activation and by modulating RNA sp

215 ell subset that controls antibody production by inhibiting T follicular helper (Tfh)-mediated help to

216 -2 prevents retrograde trafficking of toxins by inhibiting TA-protein targeting, describes a general

217 e primarily affects urinary bladder function by inhibiting TC generation and afferent nerve activity,

218 riment to downregulate the osteoclast number by inhibiting Th1 and Th17 cells, which governed the new

219 ptor on T cells mitigates renal fibrogenesis by inhibiting Th1 differentiation and renal accumulation

220 sruption by direct actin depolymerization or by inhibiting the actin driver nonmuscle myosin II (NMII

221 They function by inhibiting the activity of the Ca(2+)/calmodulin-depe

222 ins repress the expression of their own gene by inhibiting the activity of the CLOCK (CLK) and CYCLE

223 its cell motility and promotes S-phase entry by inhibiting the activity of the master regulator, CtrA

224 ng the pore-forming proteins Bax and Bak and by inhibiting the anti-apoptotic proteins Bcl-XL, Bcl-2

225 s, the Martinotti cells, gate top down input by inhibiting the apical dendrites of pyramidal cells in

226 GABAergic VTA neurons may limit wakefulness by inhibiting the arousal-promoting VTA glutamatergic an

227 and this phenotype can be partially rescued by inhibiting the Arp2/3 complex.

228 ungal effect on susceptible Fusarium species by inhibiting the ATPase activity of their myosin class

229 es by MAP65-1 confers resistance to severing by inhibiting the binding of KTN1 and identifies the str

230 demyelinating disease, which can be rescued by inhibiting the complement component C3.

231 em cells (EPSCs) from individual blastomeres by inhibiting the critical molecular pathways that predi

232 erminus indicated that light stabilizes ACS5 by inhibiting the degradation mechanism that acts throug

233 by which plants fine-tune defense responses by inhibiting the degradation of a positive player in pl

234 Wnt signaling operates by inhibiting the destruction complex and thereby reduci

235 so reduced thrombin-mediated EC permeability by inhibiting the disassembly of VE-cadherin at adherens

236 As an attractive alternative by inhibiting the DNA binding, we selected a series of h

237 romatin needed for viral gene expression and by inhibiting the DNA damage response, makes the genome

238 damaging DNA, and (c) sustaining the damage by inhibiting the DNA repair protein poly(ADP-ribose) po

239 r JH action arrested vitellogenesis, in part by inhibiting the expression of doublesex (Dsx), a key t

240 n spheno-occipital synchondrosis development by inhibiting the expression of genes involved in chondr

241 aquiline (Sirturo), which kills mycobacteria by inhibiting the F(1)F(0) ATP synthase.

242 ct on the profiles of the oxidation products by inhibiting the formation of dimeric products.

243 mportant role in reducing aldehyde formation by inhibiting the formation of o-quinone.

244 ubiquitin at Thr12 (pUbT12) controls the DDR by inhibiting the function of 53BP1, a key factor for DN

245 h rate is thought to favor species exclusion by inhibiting the growth of less competitive species.

246 ose that Nrf2 activates a metastatic program by inhibiting the heme- and Fbxo22-mediated degradation

247 idence that this "oncohistone" mutation acts by inhibiting the histone methyltransferase PRC2, the de

248 Moreover, we demonstrate that by inhibiting the interaction between CD44 and its ligan

249 ne, TNF-alpha, regulates skeletal myogenesis by inhibiting the interaction of SP1 with the Fbxl2 core

250 nuclear accumulation of PER-TIM heterodimers by inhibiting the interaction of TIM and nuclear export

251 so decreases the non-radiative rate constant by inhibiting the intramolecular motions of the incorpor

252 and pharmacological suppression of the ISR, by inhibiting the ISR-inducing double-stranded RNA-activ

253 is known to downregulate cytokine signaling by inhibiting the JAK-STAT pathway.

254 st commonly used antihypertensives, function by inhibiting the L-type voltage-gated Ca(2+) (Ca(v) ) c

255 spindle by clathrin stabilizes microtubules by inhibiting the microtubule depolymerase MCAK.

256 indlin-2 maintains alpha-tubulin acetylation by inhibiting the microtubule-associated deacetylase his

257 opose lowering neuronal mitochondrial Ca(2+) by inhibiting the mitochondrial Ca(2+) uniporter as a no

258 We find that by inhibiting the myosin phosphatase, ERK and RSK promot

259 and that they prevent expression of the tic by inhibiting the nascent excitation released by the tic

260 Similarly, we filter out unintended noise by inhibiting the native SoxRS-mediated oxidative stress

261 s G6PD, the rate-limiting enzyme of the PPP, by inhibiting the newly identified E3 ligase TIRM21 and

262 to viral infection and inflammatory stimuli by inhibiting the NF-kappaB and type I interferon (IFN-I

263 rowth of tRXRalpha-mediated colorectal tumor by inhibiting the NF-kappaB-IL-6-STAT3 signaling cascade

264 splicing pathway restricts axon regeneration by inhibiting the nonconventional splicing of Xbp1 mRNA

265 motes the photosensitizing effect of porSMNs by inhibiting the pai-pai stacking interactions of the p

266 attenuation of NF-kB/AP-1 activity upstream by inhibiting the phosphorylation of MAPKs.

267 ochondrial respiration during erythropoiesis by inhibiting the production of Cox10.

268 une system responses to infection and injury by inhibiting the production of tumor necrosis factor (T

269 RNAPII was reduced, which could be reverted by inhibiting the proteasome, indicating proteasomal deg

270 duce transcriptional changes in target cells by inhibiting the proteolytic processing of full-length

271 ults suggest that danazol exerts a CS effect by inhibiting the STAT3 pathway in MDR cancer cells and

272 wth and metastasis by inducing apoptosis and by inhibiting the STAT3 signaling pathway in cancer cell

273 from ER calcium release and were attenuated by inhibiting the store-operated calcium entry (SOCE) ch

274 ity improves myoblast differentiation partly by inhibiting the synthesis, not the degradation, of ID1

275 human neuroblastoma with TERT overexpression by inhibiting the TERT-associated gene expression networ

276 entinostat, disrupts the premetastatic niche by inhibiting the trafficking of MDSCs through the downr

277 cRel expression blocked ASC differentiation by inhibiting the transcription factor Blimp1, and in wi

278 containing miR-26a prevented muscle atrophy by inhibiting the transcription factor forkhead box O1.

279 tic function, enforces glycolytic metabolism by inhibiting the transport of pyruvate into the mitocho

280 Functionally, inactivation of STAT3 by inhibiting the upstream Janus kinase (JAK) 1 or JAK2

281 imitation is to sensitize BCBMs to radiation by inhibiting their ability to repair DNA damage.

282 e resulting oligomers to neuroblastoma cells by inhibiting their binding to the cellular membranes.

283 te transformation of LMP1-expressing B cells by inhibiting their differentiation to plasma cells.

284 omoters to induce their gene expression, and by inhibiting their interaction with phyB in the light.

285 maintained CAV1 and integrin protein amounts by inhibiting their lysosomal degradation through its en

286 transcription factors promote pinealogenesis by inhibiting this FGF activity.

287 ortalin decreased mitochondrial permeability by inhibiting this interaction.

288 ase and other enzymes, enhance VacA toxicity by inhibiting toxin degradation.

289 es FcepsilonRI expression on dendritic cells by inhibiting transcription factor binding to its promot

290 into cells and exert bacteriostatic effects by inhibiting translation.

291 ex-follicular helper T cells promotes asthma by inhibiting Treg cells.

292 y of cholinergic nerves, which was prevented by inhibiting TrkB.

293 e of these correlated networks was disrupted by inhibiting vCA1 shock responses during memory encodin

294 ism attenuates EMCV-mediated beta-cell lysis by inhibiting viral replication.

295 2-AG directly modulates pathogen function by inhibiting virulence programs essential for successfu

296 IV-1 particles and reduces HIV-1 infectivity by inhibiting virus-cell fusion.

297 t proliferation of support cells in parallel by inhibiting Wnt signaling.

298 olorectal cancer tumor organoids (tumoroids) by inhibiting Wnt/beta-catenin signaling via induction o

299 tumorigenesis in the Apc(Min/+) mouse model by inhibiting Wnt/beta-catenin signaling.

300 stricts cell proliferation in animal tissues by inhibiting Yes-associated protein (YAP or YAP1) and T