ライフサイエンスコーパス: calcium flux

1 or functional traits (increased polarity and calcium flux).

2 which signal via protein kinase C (PKC) and calcium flux.

3 when a calcium channel does open and allows calcium flux.

4 L-4F, however, fails to induce a calcium flux.

5 nal membrane complexes and regulate neuronal calcium flux.

6 unctions that are dependent on intracellular calcium flux.

7 to protect cardiomyocytes from pathological calcium flux.

8 nking receptor activation with intracellular calcium flux.

9 d phospholipase C-gamma1 phosphorylation and calcium flux.

10 in tyrosine phosphorylation but a decreased calcium flux.

11 AT)-dependent signaling without induction of calcium flux.

12 nts, including a defect in anti-IgM-mediated calcium flux.

13 te monophosphate and therefore intracellular calcium flux.

14 ing neuronal damage through NMDA-R-dependent calcium flux.

15 ell surface expression, and ligand-dependent calcium flux.

16 sity of LAT phosphorylation and the speed of calcium flux.

17 eutrophil respiratory burst, chemotaxis, and calcium flux.

18 ntaining a mutation in the pore that reduces calcium flux.

19 of calcium, which prevented an intracellular calcium flux.

20 f piconewton integrin tension coincides with calcium flux.

21 affinity and receptor activation measured by calcium flux.

22 ns lead to decreased alpha7 nAChR-associated calcium flux.

23 down altered SR phospholipid composition and calcium flux.

24 rve, independent of alterations in cytosolic calcium flux.

25 n inactive state ready for the next cellular calcium flux.

26 T cells respond forcefully to antigen after calcium flux.

27 more promiscuous ligand specificity trigger calcium flux.

28 CD3zeta, SLP76, Erk1/2, AKT, or S6 and lower calcium flux.

29 assessed by inhibition of chemokine-induced calcium flux.

30 d second, it boosts spike-evoked presynaptic calcium flux.

31 l blood mononuclear cells, and CCL2-mediated calcium flux.

32 ng phosphotyrosine signals and intracellular calcium fluxes.

33 als in endothelial cells, including Rac1 and calcium fluxes.

34 s correlated with sIgM-induced intracellular calcium fluxes.

35 737, were necessary for VCAM-1 activation of calcium fluxes.

36 ng in enhanced recruitment of Syk kinase and calcium fluxes.

37 entrate proteins that regulate transmembrane calcium fluxes.

38 transmitter-gated cation channels that show calcium fluxes.

39 This role is independent of calcium fluxes.

40 response and those that release oscillatory calcium fluxes.

41 urrents or by instabilities in intracellular calcium fluxes.

42 phosphorylation of phospholipase Cgamma2 and calcium fluxes.

43 moted activation of kinases Erk and Akt, and calcium fluxes.

44 5,6-EET potently induced a calcium flux (100 nm) in cultured DRG neurons that was c

45 Vav1 is required for TCR-induced calcium flux, activation of the ERK MAP kinase pathway,

46 respiratory burst, chemotaxis response, and calcium flux activities and exhibit neutropenia.

47 Dimeric CXCL12 activated G-protein-dependent calcium flux, adenylyl cyclase inhibition, and the rapid

48 in GCB-DLBCL lines but did not affect their calcium flux after BCR cross-linking or the proliferatio

49 served transient, oscillatory, and sustained calcium flux after contact with APC, but these behaviors

50 However, the dynamics of calcium flux after stimulation with an APC in vivo remai

51 However, SCH-C inhibited CCL2-induced calcium flux against a CCR5/CCR2b chimera consisting of

52 Galectin-9-induced intracellular calcium flux, aggregation and death of T(H)1 cells were

53 Blocking voltage and calcium flux altered mechanically induced changes in pro

54 of CYP4F18 resulted in a marked increase in calcium flux and a 220% increase in the chemotactic resp

55 Bacteria induce calcium flux and action potentials in nociceptor neurons

56 that papain-induced IL-4 production requires calcium flux and activation of PI3K and nuclear factor o

57 els of surface BCR associated with decreased calcium flux and activation-induced markers, compared wi

58 ptor signaling, but mediated by an increased calcium flux and calcineurin-mediated dephosphorylation

59 400 nM for both human and mouse F2L in both calcium flux and cAMP inhibition assays).

60 es, PKC inhibition augmented LTD4-stimulated calcium flux and cell migration assessed in transwell ch

61 imulation and is important for BCR-dependent calcium flux and cell proliferation.

62 itor, C3 toxin, inhibited both BCR-dependent calcium flux and cell proliferation.

63 approximately 2-fold increased signaling in calcium flux and chemotaxis assays relative to wild-type

64 r2, responded to human and mouse F2L in both calcium flux and chemotaxis assays with EC(50) values si

65 pite the two ligands having equal potency in calcium flux and chemotaxis assays, CCL22 showed dominan

66 all but one agonist activated intracellular calcium flux and chemotaxis in human neutrophils, irresp

67 38, and ERK activation as well as defects in calcium flux and cytokine production in vitro and expans

68 n and channel activity, leading to increased calcium flux and cytokine production.

69 put, and impaired T-cell survival but normal calcium flux and cytotoxicity, demonstrating the importa

70 ntly antagonized DAMGO-induced intracellular calcium flux and displayed varying degrees of inhibition

71 sponse by miR-17-92 resulted in the enhanced calcium flux and elevated levels of Myc itself.

72 a1 binding site of LAT (Y136F) have impaired calcium flux and Erk activation.

73 he ability to signal through PTH1R to induce calcium flux and ERK phosphorylation but not cyclic AMP

74 TAT-4BB) affected LPS-induced intracellular calcium flux and excitation in sensory neurons, and beha

75 ncluded normalization of intra-cardiomyocyte calcium flux and expression of calcium channel genes Atp

76 s erythematosus as demonstrated by increased calcium flux and global B cell hyperactivity.

77 P-YF(292)) experienced greater intracellular calcium flux and had greater increases in the levels of

78 monocytes and iDCs measured by intracellular calcium flux and immediate-early gene expression (FBJ mu

79 ta from the activity assays by intracellular calcium flux and inhibition of CCR5-mediated HIV-1 entry

80 e TCR signal cascade including inhibition of calcium flux and inhibition of multiple MAPK.

81 gh activating NK cell receptors by enhancing calcium flux and LFA-1 integrin activation.

82 ar activation as documented by the inhibited calcium flux and mast cell degranulation.

83 ns, an effect that translates into transient calcium flux and membrane depolarization ( approximately

84 gnate peptide-MHC complexes results in rapid calcium flux and migratory arrest in auto-reactive thymo

85 phorylation of InsP(3) R, thereby inhibiting calcium flux and mPT-dependent necrosis.

86 HuASM increased agonist-evoked intracellular calcium flux and myosin light chain (MLC) phosphorylatio

87 Further, ACK1 promoted calcium flux and NFAT-AP1 promoter activity and decrease

88 d integrin alphaIIbbeta3-dependent cytosolic calcium flux and phosphatidylinositol(3,4)P2 accumulatio

89 esensitization compared to serotonin in both calcium flux and phosphoinositide (PI) hydrolysis assays

90 served in LAT-deficient CTLs due to residual calcium flux and phospholipase C (PLC) activity.

91 pre-TCR) signaling further revealed impaired calcium flux and phospholipase C-gamma1-extracellular si

92 y interacts with sumoylation enzymes, blocks calcium flux and phosphorylation of Btk and TFII-I and i

93 erestingly, proximal TCR signaling including calcium flux and phosphorylation of Vav were not disrupt

94 Stretch of urothelial cells activated calcium flux and PKC translocation to membrane and nucle

95 es, and to a lesser extent, FcgammaR-induced calcium flux and reactive oxygen intermediate production

96 polarization and docking phases and required calcium flux and signaling through both the T cell recep

97 he genetic determinants of bone turnover and calcium flux and the impact of the gut microbiome on who

98 orylation for the induction of intracellular calcium flux and the subsequent activation of master reg

99 ) and CCL23-(26-99) are stronger agonists in calcium flux and Transwell CC receptor transfectant and

100 ng at the MAM to regulate ER to mitochondria calcium flux and triggering of the mPT.

101 rticipates in lytic replication by enhancing calcium flux and viral glycoprotein expression, but also

102 f TRPV1, TRPA1 and TRPM8 and the response of calcium flux and whole-cell currents evoked by their res

103 c Golgi protein that regulates intracellular calcium fluxes and apoptosis.

104 nd that during phase I, T cells exhibit weak calcium fluxes and detectable changes in cell motility.

105 ugh the repression of TCR ligation-triggered calcium fluxes and IL-2 production.

106 ge, we found that PACAP evoked intracellular calcium fluxes and increased phospho-PKC levels, as well

107 l sites that coordinate VCAM-1 activation of calcium fluxes and Rac1 during leukocyte transendothelia

108 3 receptor phosphorylation and intracellular calcium flux, and activating calcium-dependent calpain p

109 nk between Tbx5 dose, sarcoplasmic reticulum calcium flux, and AF propensity.

110 ress CCR9-mediated chemotaxis, intracellular calcium flux, and alpha4beta7-mediated cell adhesion in

111 acid, we measured chemotaxis, intracellular calcium flux, and alpha4beta7-mediated cell adhesion to

112 by causing a reduction in TCR/CD28-mediated calcium flux, and blocked activation of two regulatory e

113 t cell protease release, cytokine secretion, calcium flux, and changes in cell number and FcepsilonRI

114 bation decreased the production of H(2)O(2), calcium flux, and ERK1/2 phosphorylation.

115 ated inositol 1,4,5-triphosphate production, calcium flux, and extracellular signal-regulated kinase

116 C-gamma1 and the kinase Erk, more-persistent calcium flux, and increased production of cytokines and

117 cells with PU-H71 attenuated BCR signaling, calcium flux, and NF-kappaB signaling, ultimately leadin

118 cell linker protein (BLNK) phosphorylation, calcium flux, and nuclear factor kappaB (NFkappaB), c-ju

119 ents in their respiratory burst, chemotaxis, calcium flux, and phagocytic activities.

120 th diminished phospholipase Cgamma activity, calcium flux, and protein kinase C-betaII membrane recru

121 el 6 (TRPC6) reduced platelet activation and calcium flux, and reduced lung injury in CF mice after i

122 roterenol on histamine-induced intracellular calcium flux, and significantly attenuates histamine-sti

123 ctivities including protein quality control, calcium flux, and sterol homeostasis.

124 BCR cross-linking in terms of proliferation, calcium flux, and survival.

125 +) sequestration, enhanced trans-sarcolemmal calcium fluxes, and AF, establishing a mechanism underly

126 AM family receptors to phospholipase Cgamma, calcium fluxes, and Erk kinase.

127 eutrophil respiratory burst, chemotaxis, and calcium flux; and increased susceptibility to bacterial

128 Further testing of these lead compounds in a calcium flux assay in U937 cells yielded similar results

129 ls are selectively responsive to CysLTs in a calcium flux assay when compared with T(H)1 cells with a

130 15a, which displayed an EC50 of 23 nM in the calcium flux assay while showing no beta-arrestin recrui

131 5-HT2A, 5-HT2B, and 5-HT2C receptors in the calcium flux assay with the ultimate goal to generate se

132 -of-concept study) we have used a functional calcium-flux assay in human neuroblastoma SH-SY5Y cells

133 ements in cells expressing transporters, and calcium flux assays in cells coexpressing transporters a

134 We used high-throughput calcium-flux assays and patch clamp recordings of transi

135 All vCXCL-1s were able to induce calcium flux at a concentration of 100 nM and integrin e

136 se T-cell sensitivity for triggering initial calcium flux at fixed total pMHC density.

137 Thus, interference with the calcium flux attenuates spontaneous adhesion of CD28(nul

138 of S100A4 to CD16A, promoted by the initial calcium flux, attenuates the phosphorylation of CY, and,

139 ddition, these B cells were unable to induce calcium flux, become activated, or proliferate in respon

140 orter for intracellular calcium and examined calcium flux both in vitro and in situ.

141 ective T-cell antigen receptor (TCR)-induced calcium flux but enhanced mitogen-activated protein kina

142 lls in these mice show defective TCR-induced calcium flux but enhanced Ras/ERK activation, which is c

143 isease activity, normalizes CD3/CD28-induced calcium fluxing but fails to influence MHP, suggesting t

144 based membrane allows one to establish a net calcium flux by applying a potential step function (i.e.

145 athways that converge to enhance NMDA-evoked calcium flux by clustering NMDA receptors in modified me

146 e calcium channel facilitator that increases calcium flux by generating a larger window current and s

147 D(4) is more potent than LTE(4) for inducing calcium flux by the human MC sarcoma line LAD2, LTE(4) i

148 stimulated by calcium, and ethanol modulates calcium flux by the NMDA receptor, we hypothesized that

149 ntial vanilloid type 1 (TRPV1), and enhanced calcium flux by TRPV1-expressing DRGNs.

150 both the LPA(2) and LPA(3) receptors induce calcium fluxes by hMCs, only the LPA(2) receptor-selecti

151 h was balanced by enhanced trans-sarcolemmal calcium fluxes (calcium current and sodium/calcium excha

152 cid was critical for ERK1/2 phosphorylation, calcium flux, cell growth, and proliferation of naive CD

153 xin-1 (CCL11)-mediated eosinophil migration, calcium flux, cell polarization, and ERK1/2 activation,

154 organization, and exhibition of spontaneous calcium flux characteristic of a cardiomyocyte-like phen

155 ceptor 1 protein (CysLT(1)) expression using calcium flux, cyclic AMP, and chemotaxis assays.

156 ce and noted rescue of neurodegeneration and calcium flux defects.

157 ived mast cells inhibits FcepsilonRI-induced calcium flux, degranulation, and cytokine secretion.

158 (SLP-76) is critical for FcepsilonRI-induced calcium flux, degranulation, and cytokine secretion.

159 ling downstream of Src kinases and increased calcium flux, degranulation, and further enhanced cytoki

160 integrin activation while maintaining normal calcium flux, degranulation, and ROS generation.

161 n generation involves synergistic actions of calcium flux-dependent NFAT transcription factors and ER

162 These delays are regulated by intracellular calcium flux downstream of T cell activation.

163 see text] is primarily activated by neuronal calcium fluxes driven by synaptic mechanisms.

164 evolution of intracellular and extracellular calcium fluxes during a single beat which is away from h

165 internalization of CXCR4 yet does not induce calcium flux, ERK (ERK-1/2) phosphorylation, or chemotax

166 or cellular binding and blocks SDF-1-induced calcium flux, ERK-1/2 phosphorylation, and chemotaxis, w

167 njugates demonstrated that a single effector calcium flux event was sufficient for the degranulation

168 ulation: whereas mouse NKs required a single calcium flux event, CD8(+) T cells typically required se

169 t, CD8(+) T cells typically required several calcium flux events before perforin delivery.

170 At GluA2(Q) expressed in HEK293 cells (calcium flux experiment), the most potent compound was 1

171 affinity LFA-1 did not exhibit intracellular calcium flux, F-actin polymerization, cell polarization,

172 Surprisingly, calcium flux following engagement of CD3 was significant

173 tro, yet STAT1 and STAT3 phosphorylation and calcium flux following T cell activation are unaffected.

174 c version, which is unable to support normal calcium flux following T cell activation.

175 induced higher ERK activation and increased calcium flux following TCR stimulation compared with tha

176 of c-Jun led to increase in intracytoplasmic calcium flux following TCR stimulation.

177 Inhibiting calcium fluxes from endoplasmic reticulum stores and fro

178 y a major role in mineral weathering driving calcium fluxes from the continents to the oceans that ul

179 ysis of SCA7 mice revealed downregulation of calcium flux genes accompanied by abnormal calcium-depen

180 Calcium fluxes have been implicated in the specification

181 ing, mature immunological synapse formation, calcium flux, IL-2 production, and proliferation.

182 Simultaneous calcium-flux imaging and single-channel recording in a d

183 Inhibition of intracellular calcium flux impaired CXCL12-mediated migration of IEC-6

184 ast to the TRPA-1 activation and the ensuing calcium flux implicated in cold sensation in C. elegans,

185 CD4(+) T cells increased activation-induced calcium flux, implying that the increased miR-181a level

186 ein by FACS analysis and the LTD(4)-elicited calcium flux in a dose-dependent manner as compared with

187 esented on albumin, were shown to signal for calcium flux in a self- and cross-desensitizing manner,

188 ounds were evaluated for activity to inhibit calcium flux in both human and rat recombinant P2X(7) ce

189 nd increased phosphoinositide hydrolysis and calcium flux in both murine and human airway smooth musc

190 containing immune complexes and induction of calcium flux in CD21-deficient B cells were analyzed by

191 ated Akt phosphorylation, but down-modulated calcium flux in CD34(+) CB cells.

192 agonists ADP and 2-MeS-ADP induced specific calcium flux in cells expressing P2Y12+ Galpha16.

193 enous PtdIns-4,5-P(2) restores BCR-dependent calcium flux in cells lacking functional RhoA.

194 The role of SLC8A1 polymorphisms in altering calcium flux in cells that mediate coronary artery damag

195 ratiometric determination of agonist-induced calcium flux in fluor-loaded human platelets, was optimi

196 cribes the first use of a FLIPR to study the calcium flux in human platelets.

197 In vitro thymol directly triggered calcium flux in mast cells through transient receptor po

198 CRAMP-induced calcium flux in monocytes was desensitized by MMK-1, an

199 CCR1, CCR2b, and CCR3, and produced a normal calcium flux in mononuclear leukocytes.

200 miR-181a, which enhances activation-induced calcium flux in murine thymocytes, was expressed at sign

201 ceptor/Galphai/phospholipase C signaling for calcium flux in neutrophils.

202 P2Y and cys-LT receptors, failed to mediate calcium flux in response to leukotriene (LT) D(4) with s

203 1 on monocyte-derived DCs and diminish their calcium flux in response to stimulation by a CCR1 ligand

204 main, was necessary to enhance intracellular calcium flux in response to treatment with anti-mu.

205 Calcium flux in resting NK cells was induced with antibo

206 a role for decreased sarcoplasmic reticulum calcium flux in Tbx5-dependent AF susceptibility.

207 tion and was shown to have stimulated potent calcium flux in the human monocytic cell line.

208 and data analysis, for improved tracking of calcium flux in the Xenopus laevis embryo, lowering the

209 B ligand-induced activation of intracellular calcium flux in vitro.

210 777-treated T. b. gambiense failed to elicit calcium fluxes in BMECs, suggesting that generation of a

211 lls and THP-1 clone 15 cells, but it induced calcium fluxes in DCs.

212 Our results elucidate the role of calcium fluxes in early neural development and uncover a

213 rs, we assessed their contribution to muscle calcium fluxes in mice and tested whether they influence

214 eceptors that generate signals manifested as calcium fluxes in response to binding of the appropriate

215 e calcium reporter cameleon to track in vivo calcium fluxes in the axotomized neuron.

216 ndria accumulate that cannot properly buffer calcium fluxes in the cell.

217 erentiation events and are needed for normal calcium fluxes in the embryo.

218 ant aminophospholipids, we have now examined calcium fluxes in this subpopulation by measuring fluore

219 silonRIgamma and Syk, which mediate enhanced calcium fluxing in lupus T cells, were reversed in patie

220 tributes to anagen re-entry but does so in a calcium flux-independent fashion.

221 ) T cells have enhanced activation-dependent calcium flux, indicative of the retention of a thymocyte

222 Surprisingly, chloroquine inhibits calcium flux induced by RNA-containing ICs, suggesting t

223 evaluated functional activity by monitoring calcium flux inhibition in cell lines expressing recombi

224 limbing fiber stimulus evoking extracellular calcium flux into the cell and parallel fiber stimulus e

225 We find that intra-axonal calcium flux is accompanied by actin-Rho dependent growt

226 This calcium flux is accompanied by p75 neurotrophic factor r

227 Calcium flux is essential for entry in apicomplexan para

228 ons, this decrease in alpha7 nAChR-dependent calcium flux is expected due to haploinsufficiency of CH

229 The resulting calcium flux is released into a microliter scale thin la

230 l experiments demonstrate that NMDA-mediated calcium flux is significantly diminished by MMP-7 pretre

231 ls to influence MHP, suggesting that altered calcium fluxing is downstream or independent of mitochon

232 Although NKp46 did not enhance CD16-mediated calcium flux, it synergized with all other receptors.

233 resonance energy transfer (BRET) techniques, calcium flux measurements, and microscopy to study recep

234 ) channel polycystin-2 (PC2), resulting in a calcium flux-mediated cell cycle arrest.

235 In addition to calcium fluxes, microinjected dye tracers can be transfe

236 ignaling were abrogated, including increased calcium flux, microtubule organizing center (MTOC) polar

237 the inhibition of LLO-dependent induction of calcium flux, mitochondrial damage, and apoptosis.

238 the interplay of three important parameters (calcium fluxes, Na pumps, mitochondrial motility) at nod

239 CCL18 induced chemotaxis and calcium flux of human activated highly polarized Th2 cel

240 CCL18 induced chemotaxis and calcium flux of human CCR8-transfected cells.

241 te chemoattractant protein-1 (CCL2)-mediated calcium flux on CCR2b.

242 cell expressed and secreted) (CCL5)-mediated calcium flux on CCR5 with an IC50 of 22.8 nM but was ina

243 and that even if channels open the resulting calcium flux only rarely triggers vesicle fusion.

244 Measuring action potential, calcium flux or contraction individually misses critical

245 Despite FceRI-internalization, little calcium flux or mast cell degranulation occurred.

246 a consequence of altered signals regulating calcium flux or protein kinase C, but of ineffective cyt

247 IK3CD exhibited reduced AKT signaling, while calcium flux, RAS-MAPK activation, and proliferation wer

248 trailing edge of melanoma cells and mediates calcium flux, rear detachment, and motility.

249 f Nrxn-CTF decreases presynaptic release and calcium flux, recapitulating the deficits due to loss of

250 ges in protein concentration, while inducing calcium flux reproduced these changes.

251 ortant role that is likely downstream of the calcium flux required for microneme secretion, parasite

252 oskeletal dynamics impairs TCR/CD28-mediated calcium flux required for NFAT1-mediated c-rel transcrip

253 ay significantly greater PTH suppression and calcium flux response to elevated calcium.

254 We show that mitochondrial calcium-flux sensing might be important for regulating a

255 bronchiolar cell junctions, which triggers a calcium flux signaled through calcineurin within club ce

256 nditioned media but not for the intra-axonal calcium flux, spheroid formation, or rupture that occur

257 The resulting calcium flux stabilized dense arrays of ILPs (each enric

258 tif) receptor 2 (CCR2), induce intracellular calcium flux, stimulate TNF and CCL2 production, and inh

259 together with PAR4 potentiated PAR4-mediated calcium flux, suggested that PAR4 act as homodimers to s

260 s the geometry of the Q/R site that controls calcium flux, suggests association of TARP-stabilized li

261 ese receptors and activates a dose-dependent calcium flux that is abrogated by lactose.

262 es SHP-1 or SHP-2 but, unexpectedly, induced calcium flux that led to activation of the kinases MEK-E

263 ion with VacA did not alter the magnitude of calcium flux that occurred upon stimulation of CD4(+) T

264 a fraction of T cells to release oscillatory calcium fluxes that increase with increasing koff rates.

265 of PLN at Ser-16 and/or Thr-17 reestablishes calcium flux, the regulatory mechanism of SLN remains el

266 7pA signaling and induces chemotaxis but not calcium flux through an unidentified receptor.

267 Purkinje neurons by increasing intracellular calcium flux through calcium permeable AMPA receptors, a

268 DARC-CCR5 interaction impairs chemotaxis and calcium flux through CCR5, whereas internalization of CC

269 due to its inability to induce intracellular calcium flux through L-type calcium channels.

270 Similarly, mutagenic disruption of calcium flux through Orai1 caused PDGF to evoke redistri

271 along a uropod-pseudopod axis that required calcium flux through Orai1.

272 Calcium flux through store-operated calcium entry is a c

273 d PDGF to evoke redistribution, showing that calcium flux through the wild-type channels had been fil

274 ed in cells exposed to Abeta is initiated by calcium fluxes through Abeta channels.

275 hemotaxis that links chemoattractant-induced calcium flux to exocytosis and uropod release.

276 d calcium indicator, and used the changes in calcium flux to monitor the activity of many neurons sim

277 This calcium flux triggered the activation of Ca(2+)-calmodul

278 BMMCs has no effect on FcepsilonRI-triggered calcium flux, tyrosine phosphorylation of MAPKs or in ac

279 Phosphorylated CD16A mediates a more robust calcium flux, tyrosine phosphorylation of Syk, and proin

280 hanosensitive (as demonstrated by changes in calcium flux under applied luminal flow).

281 ondrial hyperpolarization (MHP) and enhanced calcium fluxing underlie aberrant T cell activation and

282 actant synthesis is triggered by a sustained calcium flux upon contact with necrotic tissue that requ

283 ts2 in SLE T cells resulted in a decrease in calcium flux upon TCR stimulation.

284 which we were able to detect agonist-induced calcium flux using a microfluidics-based screening platf

285 Enhanced calcium flux was also observed in adult CD4(+) recent th

286 Ang II-induced calcium flux was decreased upon inhibition of TRPC chann

287 ed in 4 s, and diacylglycerol production and calcium flux was observed in 6-7 s.

288 tuning of sarcomeric tension generation and calcium fluxing, we identify a significant relationship

289 Interestingly, physiological nonapoptotic calcium fluxes were capable of activating mu-calpain, im

290 p38MAPK, activation of phospholipase D, and calcium fluxes were equivalent in wild-type and RhoG(-/-

291 dium, which correlated with ability to evoke calcium fluxes, were canceled by K11777, but not by the

292 PAR4SFT failed to induce a calcium flux when expressed independently; however, coex

293 RNA-containing ICs induce calcium flux, whereas TLR7/8 ligand R848 do not.

294 signal-regulated kinase phosphorylation and calcium flux, which are all required for initiation of p

295 GLP-1-induced beta-arrestin recruitment and calcium flux, which suggests a form of allosteric regula

296 ox-mediated H2O2 generation was dependent on calcium flux, which was required for dissociation of the

297 TLR7 in CD4(+) T cells induced intracellular calcium flux with activation of an anergic gene-expressi

298 ha-thrombin induces wild-type PAR4 (PAR4-wt) calcium flux with an EC(50) of 110 nM, whereas mutation

299 Binding analysis and calcium flux with anti-Env-specific B cells confirmed th

300 In assays for metastin receptor binding and calcium flux with receptor-transfected HEK-293 cells, we