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1 els may be involved in the generation of the calcium spark.
2 ac myocyte in response to a small artificial calcium spark.
3 ation, calcium transients, and intracellular calcium sparks.
4 s that correspond to experimentally observed calcium sparks.
5 s diastolic depolarization and an absence of calcium sparks.
6 um, leading to contraction, often results in calcium sparks.
8 with CAL-520 and confocal imaging to capture calcium sparks after iPSC-CMs were electrically paced.
10 ly, SK channels are transiently activated by calcium sparks and calcium influx during action potentia
13 currents, whereas local calcium transients ("calcium sparks") and voltage-dependent potassium current
15 'all-or-none' behaviour which suggests that calcium sparks are indeed elementary events underlying c
17 urse of calcium spark production showed that calcium sparks are more likely to occur during the initi
19 s graded release by making the rate at which calcium sparks are recruited proportional to the whole c
20 , subcellular local calcium release signals, calcium sparks, are recruited to form each cellular calc
23 e show, on general theoretical grounds, that calcium sparks, as observed in confocal line scan images
25 en fixed sites within the cell are examined, calcium sparks have relatively constant amplitude but th
26 s among 23 exhibited measurable reduction of calcium sparks in a functional assay of RyR2 activity.
31 y of spontaneous calcium release events, or "calcium sparks," in smooth muscle, suggests an unanticip
32 um-coupled recruitment of multiple channels, calcium sparks might be abolished by a modest depletion
35 the action potential and the time course of calcium spark production showed that calcium sparks are
36 further used to highlight the criticality in calcium spark propagation in relation to inter-dyad dist
37 es in cells with sparse t-tubules or enhance calcium spark recruitment in cells with dense t-tubules;
41 The low variability of the amplitude of the calcium sparks suggests that more than one sarcoplasmic
42 lease can occur after ryanoid suppression of calcium sparks suggests the possibility of a new strateg
43 mic reticulum (SR), which was visualized as "calcium sparks." The ability of ICa to trigger calcium r
44 nnels, a reduction in functional coupling of calcium sparks to BK channel activation, and increases i
45 eveloped a method to interrogate recovery of calcium spark trigger probabilities and their amplitude
50 tivated by local transient calcium releases (calcium sparks), were present in Slo+/+ CCSM cells, but