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1 However, this view has also been called into question.
2 ss act of violence, and all assumptions were called into question.
3 effectiveness and harms of rhBMP-2 has been called into question.
4 ypass graft (CABG) surgery has recently been called into question.
5 action coordinate, yet its validity has been called into question.
6 weaning onto solid foods, have recently been called into question.
7 rm morbidity and mortality has recently been called into question.
8 rearrangement on the second allele) has been called into question.
9 gical reliability of such evaluations may be called into question.
10 e ability to autolytically activate has been called into question.
11 e hydrogen breath testing is yet again being called into question.
12 their widespread role in combination therapy called into question.
13 main olfactory epithelium, has recently been called into question.
14 ion of liquid water, which has recently been called into question.
15 ively downstaged and later resected has been called into question.
16 c species, this assumption has recently been called into question.
17 ed spurious, the underlying binding model is called into question.
18 the entire discipline of psychology has been called into question.
19 ils of extreme age have been unsuccessful or called into question.
20 to mediate these effects have recently been called into question.
21 f some scientific findings has recently been called into question.
22 ssical nucleation theory has been repeatedly called into question.
23 fort to ameliorate diet-induced obesity, but call into question a dominant role of SHIP2 in modulatin
25 of entorhinal and neocortical degeneration, calling into question a prevailing view of Alzheimer's d
31 ts involvement in mtDNA homeostasis has been called into question and has necessitated detailed analy
32 ransparency in biomedical sciences have been called into question, and scientists have been found wan
33 pecially in breast cancer patients, has been called into question, as recent clinical trials reveal o
37 , the safety of drug-eluting stents has been called into question because of an apparent increase in
38 e validity of most existing studies has been called into question because of methodological deficienc
40 ly disparate splice sites in U2 can be used, calling into question both the fate of its pairing to th
41 ter of plant domestication has recently been called into question by a number of genetic and archaeol
42 tents in diabetic patients has recently been called into question by a published meta-analysis of ran
44 I explore why research on mismatch might be called into question by changing views of what constitut
46 onitoring by the anterior cingulate has been called into question by monkey single-cell neurophysiolo
47 ence of a universal molecular clock has been called into question by observations that substitution r
48 causal nature of this relationship has been called into question by patient data suggesting that dec
49 for describing AP site replication has been called into question by recent investigations in E. coli
50 The safety of drug-eluting stents has been called into question by recent reports of increased sten
51 arker of adult beta cell neogenesis has been called into question by reports of Ngn3 expression in fu
52 the interpretation of such effects has been called into question by suggestions that neural activati
55 amics to plant-pathogen coevolution has been called into question by the presence of balanced polymor
56 e inactive slow form structures, however, is called into question by the presence of packing interact
57 alaeomagnetic stratigraphy has recently been called into question by the recognition that dated flows
59 s of a lymphatic network that drains the CNS calls into question classic models for the drainage of m
60 ure differences predicted across its surface call into question composition determinations, adding un
61 intimately coupled these two senses are, and call into question conventional views about the 'unisens
62 isting empirical findings, some of which may call into question current clinical pharmacotherapy prac
63 swelling or brain edema in the acute phase, calling into question current concepts regarding the neu
64 t low concentration (below 10 ppm) is rarely called into question, even if literature reports are not
68 ra trials reflect stage migration over time, calling into question historical data related to the ben
70 events are growing more severe and frequent, calling into question how prepared our infrastructure is
71 gulation, and intensifying social cognition, calling into question how sleep may impact these develop
72 ts present within eukaryotic cells, and also calls into question how the 'gene' should be defined.
73 of singleton variants in global surveys and call into question inferences of population expansion ba
74 e value of 'non-default', foraging behavior, calling into question its role in choice difficulty.
75 us and Halkieria, but not with Wiwaxia - and calls into question its purported relationship with moll
77 "metabolically healthy obesity" concept and calls into question its usefulness as a public health me
81 opted "biosignal" approach has recently been called into question on the grounds that subjective expe
82 ed inhibitors with selectivity that has been called into question or conventional knock-out animal mo
83 uency scales on the order of 0.01 to 0.1 Hz, call into question our basic understanding of the elasti
85 iscovery, the Chauvet cave elaborate artwork called into question our understanding of Palaeolithic a
86 y perception, however, fluctuates over time, calling into question our proposed perceptual readout of
87 ging models of circulation in the corona and calling into question our understanding of how stars los
88 rmines a key assumption in phylogenetics and calls into question our ability to disentangle ancient r
90 se of hallucinogens at a rock art site while calling into question previous assumptions concerning tr
91 ol, which will require further revision, and calls into question previously published unvalidated com
92 farms where noncrop vegetation was removed, calling into question reforms that promote vegetation re
94 ess the internal validity of their analysis, call into question some assumptions of their approach, a
100 hermore, the structure of C. hominis DHFR-TS calls into question surface electrostatic channeling as
104 ctivity categories may be converging and may call into question the assumptions around sexual mixing
106 ee glutamate in infant intake regulation and call into question the claim that formula feeding impair
107 d add to a growing list of observations that call into question the classical categorical distinction
108 lain the flexibility of leatherwood and also call into question the classical model of lignification,
111 c markers of oxidative stress, these results call into question the commonly held hypothesis that end
116 KRAS inhibitors.Significance: These results call into question the degree to which pancreatic cancer
117 for viability in vitro Overall, our results call into question the degree to which PDAC cells are ad
123 ltiple statistical and methodological issues call into question the evidence for dinosaur mesothermy.
124 y ERP category effects in the visual domain, call into question the face selectivity of the N170 and
130 when used as first-line treatment, certainly call into question the likelihood that clozapine would b
133 y but cannot alter long-term latency further call into question the possibility of achieving steriliz
136 ction of EpoR on nonhematopoietic cells, and call into question the preclinical basis for clinical st
139 d interblobs project to the thin stripes and call into question the proposition that different CO com
142 a role for lipofuscin-related cell death and call into question the rationale of treatments targeting
145 d LC8/Swa and the tighter binding of Swallow call into question the role for LC8 as a cargo adaptor p
147 vance for clinical practice and research and call into question the role of LB as a gold standard for
149 is involved in monogenic CAKUT in humans and call into question the role of some gene variants recent
150 Nase-based genomic footprinting approach and call into question the scope of detectable protein occup
151 mantle is nearly degassed of 40Ar, and they call into question the suitability of 40Ar as a monitor
153 epartures from the secondary cloverleaf form call into question the universality of the tertiary (L-s
156 or of "browning" in white adipose tissue and call into question the use of this protein as a function
159 uced survival for the older ESRD population, call into question the utility of most carotid and aorti
160 s dysregulated after dopamine depletion, but call into question the utility of pERK as a biomarker of
162 lade-specific antiviral activity of CTLs and call into question the validity of standard methods for
166 ith defined AI-2 QS systems, and in doing so call into question the widely accepted use of fimbrolide
168 e view that COP1 regulates p53 stability and call into question the wisdom of developing COP1 inhibit
169 and electrophysiological phenotype which has called into question the applicability of hiPSC-CM findi
171 concentrations (</=1 mum) in vascular tissue called into question the biological significance of NO f
172 recent genome-wide association studies have called into question the causal relationship between hig
173 n neurology, neuroimaging, and genetics have called into question the existing conceptually based psy
175 ed the role of LPG in oxidant resistance but called into question the importance of transient inhibit
177 randomized trials totaling >47 000 patients called into question the net clinical benefits of aspiri
179 ndings(10-15), and recent meta-analyses have called into question the reliability of the original emp
183 advantage conferred by the oxazolidinone and called into question the use of glycopeptides as first-l
184 ecent anatomical and functional evidence has called into question the validity of this hypothesis.
185 imple reflexes, recent in vitro studies have called into question the widely held view that synaptic
187 he 5' ends of footprints are found in yeast, calling into question the anti-Shine-Dalgarno effect's r
188 nt are realized at different spatial scales, calling into question the appropriate jurisdictional lev
189 aque had remarkable low cardiovascular risk, calling into question the appropriateness of a treat-all
190 riable responses to moonlight among species, calling into question the assumption that moonlight incr
191 stent with the uniform values expected, thus calling into question the assumptions that were used to
192 occipital versus posterior parietal cortex, calling into question the broader assumption that the al
193 arrier to the formation of large ice sheets, calling into question the common assumption that the pol
194 hown to give ambiguous or erroneous results, calling into question the composition and/or purity of n
196 official development aid targeting the goal, calling into question the distribution and efficacy of a
197 genetic CRISPR/Cas9-mediated MELK deletion, calling into question the essentiality of this kinase in
198 contribute less than 4% to fish production, calling into question the extent to which they contribut
199 er or the onset of a large thermal gradient, calling into question the fundamental structure of this
200 y effects driven by species complementarity, calling into question the generality of earlier findings
201 can and East Asian village dogs, potentially calling into question the hypothesis of an East Asian or
202 ath, Rel-deficient cells remained resistant, calling into question the importance of NF-kappaB as the
203 d with invasive disease are often conserved, calling into question the interaction of specific PorB l
204 ndent of baseline arteriographic appearance, calling into question the legitimacy of arteriography as
205 predictability of low-latitude environments, calling into question the life history strategy approach
206 of antibiotic-resistant organisms can occur, calling into question the long-term safety of azithromyc
208 f AT proteins may require accessory factors, calling into question the moniker "autotransporter."
209 train and one velogenic strain of the virus, calling into question the potential of this antibody as
210 fferences between these duplicated genes and calling into question the practice of examining the effe
211 s of the most selectively constrained genes, calling into question the prevailing view that CpG islan
213 een these epizootic versus enzootic strains, calling into question the reliability of interferon sens
214 , zebrafish lesions contain few lymphocytes, calling into question the role of adaptive immunity in f
215 cases are caused by agr-defective isolates, calling into question the role of Agr in invasive staphy
216 th increased diversification rates in ferns, calling into question the role of the canopy habitat in
218 lammatory and chronic disease settings while calling into question the significance of nitration by p
219 o-occur, similar trade-offs will be evident, calling into question the ubiquity of resistance managem
220 duce extracellular enzymes that degrade SOM, calling into question the ubiquity of the proposed mecha
221 CBs but also in histone locus bodies (HLBs), calling into question the use of coilin as an exclusive
222 conditions under which they are carried out, calling into question the use of conventional kinetic me
223 cant differences in physiology and behavior, calling into question the use of these mice in studies o
224 isproportionate lethal effects on civilians, calling into question the use of wide-area explosive wea
225 in Mycobacterium abscessus subsp. abscessus, calling into question the usefulness of macrolides for t
226 interacting animals are available, however, calling into question the utility of this behavior in th
227 commercial sea fishing goes back centuries, calling into question the validity of management conclus
228 outcomes, either with or without incentives, calling into question the value of these devices for hea
231 says used to measure 25(OH)D, however, which calls into question the ability of 25(OH)D assays to ref
233 ding of the underlying genetics increasingly calls into question the assumption that unisexuality in
235 f ID domains in regulatory proteins, it also calls into question the classical mechanical view of ene
236 ts presented with CD as their first episode, calls into question the current practice of elective res
237 en transplant access equity and outcomes and calls into question the deemphasis on HLA matching in pD
239 ate that this bias has been pervasive, which calls into question the emerging paradigm that intraspec
240 not changed as being "drug-like" but instead calls into question the entire hypothesis that "drug-lik
242 ient-level and center-level characteristics, calls into question the generalizability and validity of
244 ng rhombic distortion of the heme macrocycle calls into question the hypothesis that the axial iron o
245 and the incidence of bloodstream infections calls into question the importance of fever during the d
246 Reevaluation of the biological activity calls into question the initial exuberance surrounding t
247 d conduct of the relevant meta-analyses, and calls into question the interpretation of the evidence.
248 s finding, not reported in previous studies, calls into question the long-held hypothesis that kerati
250 me environments on land, and their discovery calls into question the possible pigment status of the f
251 Batterham et al. cannot easily be replicated calls into question the potential value of an anti-obesi
254 ute strongly to human gene expression, which calls into question the relevance of cis-regulatory inte
256 margin was predictive of DSS, multifocality calls into question the reliability of negative margin a
257 veloping and industrialized countries, which calls into question the role of energy expenditure in th
259 ontradicts the findings of other reports and calls into question the significance of this compound in
261 diagnostic test characteristics, this study calls into question the use of commercially available st
262 ges yields testable biochemical predictions, calls into question the use of nonsynonymous-to-synonymo
264 and aerial locomotion are substantial, which calls into question the value of conventional movement m
265 , Sittig et al. (2016) present research that calls into question the way laboratory mice are used to
266 rmers practiced fire-free savanna management calls into question the widely held assumption that pre-
267 t activate these same brain regions and thus call into question their specificity for processing biol
270 ariations comparable to those observed, thus calling into question their ability to predict future cl
272 ) anomalies were generally weak during 2014, calling into question their role in the USWC warming.
275 in the lunar interior have recently emerged, calling into question this long-standing lunar dogma.
277 Latino children cannot be reliably compared, calling into question traditional research strategies as
278 ata collection by businesses and governments calls into question traditional methods for protecting p
279 hould serve as diagnostic of autism, and all call into question unwarranted assumptions about autisti
280 H Stage 10, when a tubular heart has formed, calling into question when cardiac fate is specified and
283 the mechanics of retromer-based sorting and call into question whether retromer indeed functions as
285 h these associations may not be causal, they call into question whether specific subgroups of dialysi
287 These stark differences in synaptic transfer call into question whether type II neurons contribute to
288 ory nature of gambling-related problems have called into question whether this is an accurate charact
289 (K) and then to KH2, and recent studies have called into question whether VKORC1 reduces K to KH2.
290 s are born with endocrine pancreas function, calling into question whether NEUROG3 is required for hu
291 have yet to replicate predator hunting mode, calling into question whether predator impacts can be at
293 f iron supplementation in improving sFer and calls into question whether conventional measures of iro
294 lly viewed as distinct lineages, recent work calls into question whether helper CD4+ T cell subsets a
296 rphological and functional properties, which calls into question whether these are in fact distinct R
298 erlap between acute stress disorder and PTSD calls into question whether, as presently formulated, th
300 lution of avian plumage coloration have been called into question with the discoveries that most bird