ライフサイエンスコーパス: carbazole

1 zoles is reduced compared to indolo[3,2,1-jk]carbazole.

2 olecular rearrangements afford phenazine and carbazole.

3 enyl-substituted derivatives of indolo[3,2-b]carbazole.

4 ubstitution, especially by N-substitution of carbazole.

5 ctive antiangiogenic compound in coal tar is carbazole.

6 ents, diphenylnitrenium ion cyclizes to form carbazole.

7 ton transfer that forms the H-4a tautomer of carbazole.

8 njugated p-(ethynylphenylene), surrounded by carbazole.

9 ibenzothiophene approximately dibenzofuran < carbazole.

10 matization sequence to produce the 2,3-fused carbazole.

11 ne-fused benzo[a]carbazoles and indolo[2,3-a]carbazoles.

12 h accepts a broad range of large indoles and carbazoles.

13 showed various patterns among polybrominated carbazoles.

14 -catalyzed N-arylations and N-alkylations of carbazoles.

15 as compared to those observed in substituted carbazoles.

16 pi orbitals is lower as compared to that of carbazoles.

17 es were converted to 5,7-dihydroindolo[2,3-b]carbazoles.

18 c halonium species for the iodination of the carbazoles.

19 alyst-promoted electrophilic halogenation of carbazoles.

20 Synthesis of indolo[6,7-a]pyrrolo[3,4-c]carbazoles 1, a new class of cyclin D1/CDK4 inhibitors,

21 inhibition by 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (Ex-527).

22 4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]- 9H-carbazole-1-carboxamide 6 (BMS-935177) was selected to a

23 (selisistat; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide) can suppress HD pathology cause

24 A series of carbazole/1,3,4-oxadiazole hybrid molecules is described

25 -methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-p ropanenitrile and mitogen-activated prote

26 ,19,21-tetraphenyldiphenanthro[9,10-b:9,10-h]carbazole (15), a very crowded carbazole that exhibits a

27 the expected bianthryl derivative 15 and the carbazole 16, whereas the 9-aminophenanthrene (10), 3-ph

28 roduced almost exclusively the corresponding carbazoles 19, 20, and 21, respectively.

29 ge transfer (ICT) is observed from the donor carbazole/2,7-dimethoxycarbazole to the acceptor phenyl/

30 An array of carbazoles (23 examples) can be synthesized from substit

31 advancing 3,4-dihydro-9a,4a-(iminoethano)-9H-carbazole 27 to (+)-minfiensine.

32 le (terCBz) and N3,N3,N6,N6-tetra-p-tolyl-9H-carbazole-3,6-diamine (TTAC).

33 3-formyl-6-methoxy-carbazole, and 6-methoxy-carbazole-3-methylcarboxylate natural alkaloids.

34 9-Ethyl-N-(3,4,5-trimethoxyphenyl)-carbazole-3-sulfonamide (11a) showed significant antitum

35 A 1,2,3,4-tetrahydro-9a,4a-(iminoethano)-9H-carbazole (4) is a central structural feature of the Str

36 e products or intramolecular ones to furnish carbazole-4-carboxylates in mostly good to excellent yie

37 -(3-hydroxypropyl)indeno[2,1-a]pyrrolo[3,4-c]carbazole-5- ones revealed an optimal R9 substitution wi

38 n of the dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-one R(2) and R(12) positions led to the iden

39 ptimized synthetic route to pyrrolo[3,2,1-jk]carbazole (54% overall yield in two steps from indole).

40 With this approach, highly substituted carbazole (6), benzothiophene (10), and quinoline (14) d

41 y-hetarenes, as demonstrated for the hydroxy-carbazole 7 and the hydroxy-benzothiophene 11.

42 onplanar dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-7-one (8) and corresponding 5,7-dione (7) as p

43 shift, with k(H)/k(D) = 3.4 at 298 K to form carbazole 9 and smaller amounts of two other isocarbazol

44 Azacycloheptatetraene 1f ultimately forms carbazole 9 on the millisecond time scale by the pathway

45 red by cyclomerization reaction of 4,5-bis(6-carbazole-9-yl-hexylsulfanil)phthalonitrile in the prese

46 To this end, carbazole acetamide scaffolds were synthesized and struc

47 or seven-membered heteroaromatics (indoles, carbazoles, acridines, and dibenzazepines).

48 ct of the steric bulk groups and pai-stacked carbazoles affords PHDPF-Cz as an ultrastable property,

49 Mahanine, a carbazole alkaloid is a potent anticancer molecule.

50 In addition, ancorinazole, an indolo[3,2-a]carbazole also possessing sulfamate and sulfate groups,

51 Poly[N-9''-heptadecanyl-2,7-carbazole-alt-5,5-(4',7'-di-2-thienyl-2',1',3'-benzot hi

52 n dissociation within the poly(N-decanyl-2,7-carbazole-alt-9,9-dioctylfluorene) (PCzF)/g-C3 N4 PHJ, a

53 This method has also been used to synthesize carbazoles, although a higher reaction temperature is ne

54 atalyzed C-H bond amination reaction to form carbazoles, an important motif that is prevalent in a ra

55 y, we designed and synthesized a fluorescent carbazole analogue of mahanine (alkaloid from Murraya ko

56 f annulated thiophene, dibenzothiophene, and carbazoles analogues has been achieved involving alkylat

57 e the response of NH-containing fluorophores carbazole and 2-phenylbenzimidazole (Ph-BIM) with two re

58 etal-free N-H functionalization reactions of carbazole and azepine heterocycles (15 examples, up to 8

59 ne-BF(2)bdk triads CDB1 and CDB2, suspending carbazole and BF(2)bdk moieties on both sides of dithien

60 ncipal subunits of carvedilol, including the carbazole and catechol moieties, as well as the linker c

61 Carbazole and derivatives may be useful in the therapy o

62 ee different types of reaction products with carbazole and Ph-BIM.

63 and six-member benzo-fused heterocycles (9H-carbazole and phenanthridine) when an aromatic amide ani

64 an oxygen molecule, prompts the formation of carbazole and phenoxazine in a facile mechanism.

65 novel series of highly potent and selective carbazole and tetrahydrocarbazole based, reversible inhi

66 Carbazole and trityl substrates with two groups show sat

67 electrophilic borylation can be extended to carbazoles and anilines with excellent ortho selectivity

68 general for N-N dimerization of substituted carbazoles and beta-carbolines, providing entry into sel

69 lly extended to the synthesis of substituted carbazoles and dibenzothiophenes.

70 corresponding 3-pyrrolin-2-one-fused benzo[a]carbazoles and indolo[2,3-a]carbazoles.

71 pper catalyst, nitrogen nucleophiles such as carbazoles and primary amides undergo C-N coupling with

72 azole was one of the most active halogenated carbazoles and, like TCDD, contains 4 lateral substituen

73 synthesis of glycozoline, 3-formyl-6-methoxy-carbazole, and 6-methoxy-carbazole-3-methylcarboxylate n

74 pentachlorobiphenyl (PCB-126), indolo[3,2-b]-carbazole, and beta-naphthoflavone.

75 useful precursors of cyanocyclopentadienes, carbazoles, and aza-analogues.

76 uding naphtols, phenols, pyridines, indoles, carbazoles, and thiophenes in combination with amines an

77 f three regioisomeric thienopyrrolo[3,2,1-jk]carbazoles applying a convenient C-H activation approach

78 Differently substituted carbazoles are examined to showcase regioselective discr

79 ctral shift data for 11 relevant halogenated carbazoles are reported, along with their gas chromatogr

80 750 to 950 degrees C gives pyrrolo[3,2,1-jk]carbazole as the major product.

81 The reaction could also be carried out using carbazoles as sensitizers, and quantitative yields could

82 safer and more specific than the traditional carbazole assay.

83 loped to prepare suitably substituted stable carbazoles B1-B3, G1-G3, and R1-R3.

84 Two benzoylpyridine-carbazole based fluorescence materials DCBPy and DTCBPy,

85 A new class of highly fluorescent and stable carbazole-based dendrimers (1-5) that contain the ethyny

86 In the present study, carbazole-based diaza[6]helicenes were synthesized utili

87 ed donor-acceptor materials, using dendritic carbazole-based donors 9'H-9,3':6'9"-tercarbazole (terCB

88 ure the rates of regeneration of six organic carbazole-based dyes by nine ferrocene derivatives whose

89 porous fibers fabricated by self-assembly of carbazole-based macrocyclic molecules.

90 vided higher regioselectivity in the case of carbazole-based substrates.

91 A new carbazole-based tetraimidazole ligand 1,3,6,8-tetra(1H-i

92 5',5',5',4',4'-pentafluoro-1',3'-dioxopentyl)carbazole (bdc), was synthesized to efficiently excite e

93 least 24 isomer groups, including alkylated carbazoles, benzocarbazoles, and indenoquinolines.

94 Multiple donor-acceptor-type carbazole-benzonitrile derivatives that exhibit thermall

95 The 3,6-carbazole binds approximately twice as strongly to the G

96 thermal stability attributable to the rigid carbazole building block.

97 otocol for the preparation of a series of 9H-carbazoles by photostimulated SRN1 substitution reaction

98 xt, the current study focuses on a series of carbazole-(C=C)(n)-2,5-diphenyl-1,3,4-oxadiazoles (n = 1

99 (C18H13Cl11), and a novel mixed chloro/bromo-carbazole (C12H5NCl2Br2) in a number of sediments analyz

100 N-H carbazoles can be produced from 2-chloroanilines and ary

101 The P7C3 class of aminopropyl carbazole chemicals fosters the survival of neurons in a

102 apid cyclization reaction to furnish all new carbazole compounds through installation of a great dive

103 An arylated-carbazole conjugated polymer with a deep HOMO level has

104 gn and syntheses of four novel benzimidazole-carbazole conjugates and demonstrate their high binding

105 les, while the others were mixed halogenated carbazoles containing, in addition to bromine, either ch

106 The carbazole-containing molecule TAM4 after oxidation under

107 environment as a result of the production of carbazole-containing polymers present in a wide variety

108 semiconductors (HTPS), which are based on a carbazole core and the oxiran and thiiran reactive group

109 The indolo[3,2-b]carbazole core has a larger resonance structure that inc

110 -stage functionalizations of a pyrano[3,2- a]carbazole core related to the murrayamine natural produc

111 allel strategies were exploited to forge the carbazole core: 6pi-electrocyclization/aromatization and

112 the 9-position as steric bulk moieties, and carbazole (Cz) units localize at the 4-position as supra

113 pounds (including pharmacologically relevant carbazoles, delta-lactams, and oxindole derivatives).

114 pplied to synthesize the core of a bioactive carbazole derivative in a concise manner.

115 reactions toward a series of polyphenylated carbazole derivatives differing in their N-substitution

116 Specifically, cyclization to form carbazole derivatives occurs negligibly, if at all, with

117 tuents and the core moiety, the indolo[3,2-b]carbazole derivatives studied all have a weaker coupling

118 lysubstituted cyclopentene and cyclopenta[ b]carbazole derivatives through the iodine-promoted electr

119 nishes highly substituted and functionalized carbazole derivatives via a double annulation process th

120 , based on conjugates of aminoadamantane and carbazole derivatives was synthesized and investigated.

121 as coupling partners, whereas cyclopenta[ b]carbazole derivatives were produced via 6pai electrocycl

122 ons of this methodology synthesizing diverse carbazole derivatives, i.e., both electron-rich and elec

123 vel substrates: trityl (triphenylmethyl) and carbazole derivatives.

124 o that of the previously reported dicationic carbazole derivatives.

125 Synthesized carbazole derived with fluorophore compound 12 was disco

126 oach, we tested anti-trypanosomal effects of carbazole-derived compounds called "Curaxins".

127 Ancorinazole is the first indolo[3,2-a]carbazole described as a natural product.

128 Among these was an aminopropyl carbazole, designated P7C3, endowed with favorable pharm

129 nthetic and natural product-based tricyclic (carbazole, dibenzo[b,d]furan, and dibenzo[b,d]thiophene)

130 Introduction of planarized fluorene, carbazole, dibenzo[b,d]thiophene or dibenzo[b,d]thiophen

131 with core units comprising dibenzothiophene, carbazole, dibenzofuran and fluorene.

132 Substituted carbazoles, dibenzofurans, and tricyclic compounds conta

133 cellent separation (by LC and GC methods) of carbazole, dibenzothiophene, fluorenones, xanthones, and

134 sequence-dependent DNA binding properties of carbazole dications.

135 ated indole rings leading to carbazolo[2,3-b]carbazole diimides (CbDIs) with exclusive syn-connectivi

136 (BMVC, 3, 6-bis-(1-methyl-4-vinylpyridinium)-carbazole diiodide) and duplex-binding fluorophores (Hoe

137 In this study, two carbazole-dithienylethene-BF(2)bdk triads CDB1 and CDB2,

138 w electron-accepting units and di(tert-butyl)carbazole (DTC) as the electron-donating units.

139 n (aromatization) of this to give the target carbazole (e.g. 4).

140 methyl-5-oxo-5H-indolo(2,3-a)py rrolo(3,4-c)-carbazole], enhanced basal and agonist-stimulated phosph

141 refore, the developed thienopyrrolo[3,2,1-jk]carbazoles enrich the family of triarylamine donors and

142 oxyphenyl)-6-pentyl-5,11-dihydroindolo[3,2-b]carbazole exceed 10(-3) cm(2)/V.s at high electric field

143 Some halogenated carbazoles exhibit characteristics of persistent organic

144 he high-affinity ligand 6-formylindolo[3,2-b]carbazole (FICZ) determines a boost in degranulation.

145 The AHR ligand, 6-formylindolo[3,2b]carbazole (FICZ) was used to activate the AHR pathway in

146 d scalable synthesis of 6-formylindolo[3,2-b]carbazole (FICZ), a naturally-occurring aryl hydrocarbon

147 Here we report that 6-formylindolo[3,2-b]carbazole (FICZ), a tryptophan photoproduct and endogeno

148 obiphenyl (PCB126), and 6-formylindolo[3,2-b]carbazole (FICZ), also activated the gmAhr proteins, but

149 tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ), an aryl hydrocarbon receptor ligand, h

150 ered systemic levels of 6-formylindolo[3,2-b]carbazole (FICZ), an enigmatic endogenous ligand for the

151 onists including TCDD, 6-formylindolo-[3,2-b]carbazole (FICZ), and 3-3'-diindolylmethane (DIM) and th

152 arbon receptor agonist 6-formylindolo[3,2-b] carbazole (FICZ), is a UVB photoproduct of tryptophan an

153 endogenous AhR ligand, 6-formylindolo(3,2-b)carbazole (FICZ), on the differentiation and functions o

154 ibenzodioxin (TCDD) and 6-formylindolo[3,2-b]carbazole (FICZ).

155 oproduct and AhR ligand 6-formylindolo[3,2-b]carbazole (FICZ).

156 among a series of 6-substituted indolo[3,2-b]carbazoles for activation of AhR in cells.

157 re a palladium-catalyzed construction of the carbazole framework and an annulation of the pyran ring,

158 aped (LXL)Au(I)-pincer complexes, based on a carbazole framework flanked by two mesoionic carbenes (M

159 A highly efficient protocol to access carbazole from donor-acceptor cyclopropane and indonyl a

160 al and efficient synthesis of 4,9-dihydro-1H-carbazoles from 3-allenylmethylindoles is reported.

161 es the mild and stereoselective formation of carbazoles from biaryl azides.

162 The synthesis of a series of substituted carbazoles from the corresponding 2-nitrobiphenyl deriva

163 overning the formation of benzimidazoles and carbazoles from the reaction of N-(biphenyl)pyridin-2-am

164 fonium salt of a carbamato borate based on a carbazole function, its establishment as a PhLAG, and th

165 New thiophene-carbazole functional and cross-linking monomers electrop

166 methyl-5-oxo-5H-indolo(2,3-a)pyr rolo(3,4-c)-carbazole (Go 6976), a specific inhibitor of Ca(2+)-depe

167 methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3, 4-c)-carbazole (Go 6976), an inhibitor of calcium-dependent P

168 methyl-5-oxo-5H-indolo[2,3-a]py rrolo[3,4-c] carbazole], Go6983 [2-[1-(3-dimethylaminopropyl)-5-metho

169 se of strong electron-donating properties of carbazole group.

170 N-Substituted carbazole has also been prepared by following this metho

171 positions octa-substituted with alkyl linked carbazole has been prepared by cyclomerization reaction

172 ctrophilic chloroquinoline and electron-rich carbazole has opened up new opportunities.

173 Pd(II)-catalyzed direct synthesis of benzo[a]carbazoles has been achieved through aminopalladation of

174 ent one-pot protocol for the synthesis of NH-carbazoles has been described.

175 sis of aryl and heteroaryl-annulated cyclo[b]carbazoles has been developed via SnCl4-mediated one-pot

176 A copper-catalyzed iodination of carbazoles has been developed.

177 The carbazoles have been shown to arise directly from the co

178 The first substituted pyrrolo[3,2,1-jk]carbazoles have been synthesized by FVP methods and also

179 ported the discovery of P7C3, an aminopropyl carbazole having proneurogenic and neuroprotective prope

180 ported the discovery of P7C3, an aminopropyl carbazole having proneurogenic and neuroprotective prope

181 noid ring in fused polycyclic heteroaromatic carbazole (i.e., [2,3]-benzoindole) skeletons.

182 ther, administration of 6-formylindolo[3,2-b]carbazole in vivo enhances NK cell control of tumors in

183 ropargyl indoles to afford the corresponding carbazoles in decent yields.

184 icipated highly substituted naphthalenes and carbazoles in good to excellent yields.

185 provides 3,4-dihydro-9a,4a-(iminoethano)-9H-carbazoles in high enantiomeric purity.

186 present strategy to provide di- and triaryl carbazoles in one pot involves benzannulation through di

187 tudy discovering the seven mixed halogenated carbazoles in the environment.

188 resulting in the direct synthesis of benzo[a]carbazoles in which a wide variation of substituents at

189 onding C-N coupled products, N-R-substituted carbazoles, in 82-98% yield.

190 d can be used in the synthesis of a range of carbazoles, including the natural products Clausine P an

191 twisted 89 degrees from the plane of central carbazole, indicating a lack of electron delocalization

192 Substituted carbazoles, indoles, and dibenzofurans are readily prepa

193 In addition to antiangiogenic activity, carbazole inhibited the production of inflammatory IL-15

194 on by the agonist FICZ (6-formylindolo[3,2-b]carbazole) inhibited NMuMG migration, whereas the antago

195 on series of potent and selective reversible carbazole inhibitors of BTK.

196 hand, AHR activation by 6-formylindolo[3,2-b]carbazole interfered with T(reg) cell development, boost

197 he post functionalization of the substituted carbazole into a fully conjugated pai-system exhibiting

198 angiogenic and anti-inflammatory activities, carbazole is likely a major component of the antipsoriat

199 flexible approach to 3-pyrrolin-2-one fused carbazoles is disclosed.

200 s to 6-arylbenzimidazoles and N-pyridinyl-9H-carbazoles is presented.

201 UMO energy gap of the thienopyrrolo[3,2,1-jk]carbazoles is reduced compared to indolo[3,2,1-jk]carbaz

202 new method for the assembly of unsymmetrical carbazoles is reported.

203 yl)-10,15-dihydro-5H-diindolo[3,2-a:3', 2'-c]carbazole (KR131) with compositive perovskite absorber.

204 1,3,6,8-tetra(1H-imidazol-1-yl)-9-methyl-9H-carbazole (L) has been synthesized.

205 lization of the 3,6-bis-styryl derivative of carbazole leading to sterically less demanding aza[7]hel

206 easing heteroaromaticity (dibenzothiophene < carbazole < dibenzofuran).

207 ted here to the possibility that halogenated carbazoles may currently be emitted into the environment

208 conjugated cyclic motifs are presented with carbazole moieties as donors and borane moieties as acce

209 -5 consists of rigid, aromatic porphyrin and carbazole moieties as well as linear ethynylene linkers,

210 The purpose of combining of carbazole moieties with phthalocyanine on the peripheral

211 induced benzannulation sequence to forge the carbazole moiety characteristic of these natural product

212 a carbaldehyde or malononitrile group on the carbazole moiety is found to quench fluorescence severel

213 ction of 2,7-dimethoxy substituents onto the carbazole moiety lowers the value of E(S), although E(T)

214 ible by a self-assembled, methyl-substituted carbazole monolayer as the hole-selective layer in the p

215 We have identified an amino-alcohol carbazole (N-CBZ) as a PfHsp90-selective inhibitor by vi

216 This aminopropyl carbazole, named P7C3, is orally bioavailable, crosses t

217 to diphenylamino substituted derivatives of carbazole, no effect of the position of methoxy groups o

218 on is possible via ligation of a cyano-vinyl carbazole nucleoside with an opposite thymine when irrad

219 t; thus, a change from NH- to N-decyl on the carbazole nucleus was carried out.

220 The effect of carbazole on upstream pathways in human psoriasis was de

221 ate substitution methodologies on the parent carbazole or by palladium-catalyzed cyclization of di-(p

222 The molecular arms are based on a carbazole or oligo(phenylene ethynylene) core with a str

223 Other dietary factors such as carbazoles or tryptophan-enriched proteins have anti-inf

224 phene S,S-dioxide and the donor is fluorene, carbazole, or arylamine.

225 -methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3 ,4-c]carbazole] or PKC-alpha short hairpin RNA.

226 The abundance of mixed halogenated carbazoles peaked at depths of 12-16 cm, remained at rel

227 ures for a total of 15 novel polyhalogenated carbazoles (PHCs) with the general molecular formula C12

228 Polyhalogenated carbazoles (PHCZs) have been increasingly detected in th

229 veral other nitrogen heterocycles, including carbazole, phenothiazines, and tetrahydroquinoline.

230 and the experimental profiles of chlorinated carbazole, phenoxazine, and phenazine suggests the forma

231 the three nitrogenated dioxin-like species, carbazole, phenoxazine, and phenazine via unimolecular r

232 Carbazoles possessing complex molecular architecture can

233 Oxidative C-C coupling of carbazoles possessing various substituents is demonstrat

234 tryptophan derivative, 6-formylindolo[3,2-b]carbazole, potentiates NK cell IFN-gamma production and

235 similar or different) substrates from acetyl carbazole proceeds via a stepwise pathway.

236 The substitution pattern of the carbazole product can be controlled by the design of the

237 under extremely mild conditions and produces carbazole products in good to excellent yields.

238 broad range of functional groups, and yield carbazole products in the absence of unwanted side produ

239 P7C3 aminopropyl carbazoles promote neuronal survival by enhancing nicoti

240 , purine, indazole, benzimidazole, pyridone, carbazole), providing a versatile method for the synthes

241 aining an electroactive polymer, polyvinyl-N-carbazole (PVK) (97 wt %), and single-walled carbon nano

242 n-relay mechanism: the transiently generated carbazole radical cation acts as an oxidant to return th

243 Finally, a mechanism that involves the carbazole radical cation has been traced (evidenced) and

244 C3-substituted indoles and carbazoles react with alpha-aryl-alpha-diazoesters under

245 he position of the two amidine groups on the carbazole ring influences significantly the drug-DNA int

246 lization of di-(p-tolyl)amine to provide the carbazole ring system.

247 are formed by an electron donor moiety, the carbazole ring, and an electron acceptor moiety, the pol

248 mately 90 degrees between the phenyl and the carbazole rings due to steric interactions.

249 comparison to the analogous indolo[3,2,1-jk]carbazole scaffold.

250 ]thiophene > dibenzo[b,d]furan > 9-methyl-9H-carbazole series.

251 upon self-assembly of a monolayer of t-butyl carbazole-substituted phosphonic acid molecules and subs

252 ass of calixpyrrole analogue, containing two carbazole subunits in lieu of two of the four acetone br

253 Carbazole sulfonamides are a novel promising class of an

254 Two series of carbazole sulfonamides related to Combretastatin A4 (1)

255 heterocycles, such as indoles, pyrazole, and carbazole, sulfonamides, as well as electron-deficient a

256 acids, and other oxygen-containing species, carbazoles, sulfones, and thiophenes from small crude oi

257 itutes the first example of a multicomponent carbazole synthesis.

258 nd strong donors in the arms (diarylamine or carbazole), TAM1-TAM3 exhibit large solvatochromic effec

259 Precursor carbazole terminated dendrons and dendrimers up to gener

260 9,10-b:9,10-h]carbazole (15), a very crowded carbazole that exhibits an 81 degree end-to-end twist bu

261 We have found that any carbazole that is not substituted in the 1,3,6,8 positio

262 onstrated by synthesizing highly substituted carbazoles through a simple extension of this method to

263 oduce valuable fused 5,7-dihydroindolo[2,3-b]carbazoles through the functionalization of two indole C

264 .g., N,N-dimethylaniline, diphenylamine, and carbazole) through an initial one-electron transfer.

265 ide array of indoles, as well as pyrrole and carbazole, to afford the corresponding N-alkylation prod

266 Carbazole treatment also reduced activity of inducible n

267 Recognition properties of the novel bis(carbazole) tris-ureidic-based receptors 1 and 2 toward d

268 The redox properties of the carbazole unit can thus be rationally tuned to improve c

269 vealed that copolymerizing electron-donating carbazole unit into the poly(9,9-dioctylfluorene) backbo

270 ation functionalization via substituting the carbazole unit provides a platform for the synthesis of

271 tion rate and the reduction potential of the carbazole unit tethered to the aminocatalyst.

272 chemical structure featuring a disubstituted carbazole unit, five stereogenic centres-three of which

273 The carbazole unit, however, is also involved in another ste

274 hiral amine catalyst, bearing a redox-active carbazole unit, which could rapidly reduce the highly re

275 alized via electrophilic substitution on the carbazole unit.

276 surroundings and the electronics of the core carbazole unit.

277 e (AAA), two (AAB), or three (ABC) different carbazole units, we needed to subvert the synthetic pref

278 rence of electronic coupling between the two carbazole units, which is modulated by their relative di

279 system carrying halogen substituents at the carbazole units.

280 These precatalysts produce N-substituted carbazoles upon activation, which cannot consume startin

281 PHCZs were analyzed along with unsubstituted carbazole using gas chromatography coupled with single-

282 general palladium-catalyzed monoacylation of carbazoles using toluene derivatives playing the dual ro

283 entially converted into a highly substituted carbazole via a retro-4pi/6pi-electrocyclization-N-acyla

284 enes, phenanthrenes, quinolines, and benzo[b]carbazoles via Knoevenagel condensation, C-arylation, an

285 for the synthesis of a series of chlorinated carbazoles via the Cadogan cyclization is also demonstra

286 Carbazole was found to inhibit rac activation as a mecha

287 hways in human psoriasis was determined, and carbazole was shown to inhibit signal transducer and act

288 on responses for the most active halogenated carbazoles was similar to that observed for 2,3,7,8-tetr

289 sive MDA-MB-468 breast cancer cells by these carbazoles was similar to that observed for other dioxin

290 s of three derivatives of 1,8-di(pyrid-2'-yl)carbazole were prepared by Stille-type coupling of 2-(tr

291 The carbazoles were prepared by appropriate substitution met

292 ubstituted pyrazoles, pyrroles, indoles, and carbazoles were screened to identify potential inhibitor

293 A series of thienylphenothiazine decorated carbazoles were synthesized and characterized by optical

294 Substituted 9H-carbazoles were synthesized in low to excellent yields (

295 hs compared to the analogous indolo[3,2,1-jk]carbazole, whereas the emission maxima of the sulfur der

296 ere tentatively identified as polybrominated carbazoles, while the others were mixed halogenated carb

297 e photoinduced, copper-catalyzed coupling of carbazole with alkyl bromides.

298 erization of new derivatives of indolo[3,2-b]carbazole with differently substituted phenyl groups at

299 )-P7C3-S243 is a neuroprotective aminopropyl carbazole with improved druglike properties compared wit

300 this approach is not limited to reactions of carbazoles with iodobenzene and alkyl halides.