ライフサイエンスコーパス: carbene

1 )(CH(3))P, where NHC(R) is an N-heterocyclic carbene).

2 a highly sterically hindered N-heterocyclic carbene.

3 penes give dimerizations of the intermediate carbene.

4 rdination sites and the first true dianionic carbene.

5 cult functional groups to be appended to the carbene.

6 y means of C-H insertion with donor/acceptor carbenes.

7 lylation reaction and migratory insertion of carbenes.

8 lts in nitrogen elimination and formation of carbenes.

9 tures that influence the stability of siloxy carbenes.

10 val those of ylide-stabilized N-heterocyclic carbenes.

11 IM) with two representative isolable singlet carbenes.

12 of a large variety of pyridinium salts with carbenes.

13 fragments, such as carbodiphosphoranes and -carbenes.

14 and a vacant orbital, reminiscent of singlet carbenes.

15 es are consistent with those of nucleophilic carbenes.

16 tion chemistry of oxidatively generated gold carbenes.

17 metric redox-active Au(I) bis-N-heterocyclic carbenes.

18 l for scaling the pai-accepting character of carbenes.

19 thus genuinely making it isoelectronic with carbenes.

20 Specifically, N-heterocyclic carbene 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene

21 Carbene 1cc converts quickly to 1ct via quantum-mechanic

22 zol-2-ylidene (IPr) and cyclic (alkyl)(amino)carbene (2,6-diisopropylphenyl)-4,4-diethyl-2,2-dimethyl

23 n we report that a stable singlet ambiphilic carbene activates CO and catalytically promotes the carb

24 Here we demonstrate that carbene active centers localized on carbon atoms at the

25 ively and covers the usage of N-heterocyclic carbene adducts of the p-block elements as ligands in tr

26 possible modifications that could improve Au-carbene affinity and specificity for G-quadruplex bindin

27 e order Ag < Au < Cu, with the lifetimes of (carbene)Ag(Cz) roughly a factor of 10 shorter than for (

28 In contrast, the deuterated (OD) carbene analogue showed much reduced 1,2-D-shift reactiv

29 carbazolyl) (M(MAC)) complexes show coplanar carbene and carbzole ligands and C-M-N bond angles of ~1

30 ed to show competitive production of singlet carbene and ketene intermediates from the photoexcitatio

31 ecifically the physical organic chemistry of carbenes and carbocations.

32 labile and can reversibly dissociate to free carbenes and fluorophores to varying extents.

33 tor ligands in homogeneous catalysis such as carbenes and phosphines.

34 lopment of this chemistry are donor/acceptor carbenes and the chiral dirhodium tetracarboxylate catal

35 arate sections including generation of vinyl carbenes and their reactions, metathesis processes, hete

36 red, through proper choice of the acceptor (carbene) and donor (carbazolyl) groups.

37 l-enones were reacted with an N-heterocyclic carbene, and an intramolecular Stetter reaction proceede

38 Carbenes are important intermediates in organic chemistr

39 Donor/donor carbenes are relatively new in the field of carbene chem

40 and reduced pnictonium-stabilisation of the carbene as group 15 is descended, which is supported by

41 The emergence of N-heterocyclic carbenes as ligands across the Periodic Table had an imp

42 p = 2,6-iPr(2)C(6)H(3); NHC = N-heterocyclic carbene] as red crystalline solids containing a pai-dono

43 A series of (carbene)Au((I))(aryl) complexes are reported.

44 ement for these classes of anionic mesoionic carbene-based ligands.

45 synthesis of storable bicyclic (alkyl)(amino)carbenes (BICAACs), which feature enhanced sigma-donatin

46 tional mobility was observed for a single Au-carbene binding at the second G-quadruplex surface.

47 ter understand the molecular mechanism of Au-carbene binding to G-quadruplexes, we employed molecular

48 tegy capitalizes on the formation of a metal-carbene bond which induces an axis of chirality.

49 l ligands including thiols and amines, metal-carbene bonds that are stable under reductive potentials

50 molysis in the presence of an N-heterocyclic carbene borane (NHC-borane) and di-tert-butyl peroxide.

51 undec-3-ene-1,5-diyne with an N-heterocyclic carbene borane.

52 Reactions of N-heterocyclic carbene boranes (NHC-boranes) with electron-poor aromati

53 Since the postulation of carbenes by Buchner (1903) and Staudinger (1912) as elec

54 d illustrate the scope of the donor/acceptor carbene C-H functionalization.

55 ecular alkylation of sp(3) C-H bonds through carbene C-H insertion.

56 lso partly delocalized over the CAAC ligand (carbene) C and N atoms.

57 s productivity of leading cyclic alkyl amino carbene (CAAC) catalysts relative to their important N-h

58 )Br(4) coordinated by a cyclic (alkyl)(amino)carbene (cAAC) in a 3:1 ratio affords a neutral tetrabor

59 e 2 was converted to a cyclic (alkyl) (amino)carbene (cAAC) via 1,2-hydrogen migration triggered by b

60 able boraphosphaketene, cyclic(alkyl)(amino) carbene (CAAC)-borafluorene-P=C=O (2), is described.

61 clic carbene (NHC)- and cyclic (alkyl)(amino)carbene (CAAC)-stabilized borafluorene radicals have bee

62 zed by a state-of-the-art cyclic alkyl amino carbene (CAAC, C1) and a bridging chloride donor: the la

63 cyclic (amino)(alkyl), monoamido, or diamido carbenes (CAAC, MAC, or DAC, respectively) as chromophor

64 Cyclic (alkyl)- and (aryl)-(amino)carbenes (CAACs and CAArCs) are stronger sigma-donors an

65 arbene carbon centre in cyclic (alkyl)(amino)carbenes (CAACs) is known to exhibit transition-metal-li

66 perties compared to monocyclic (alkyl)(amino)carbenes (CAACs).

67 r(I) complexes bearing a cyclic (amino)(aryl)carbene (CAArC) ligand with various complex geometries h

68 The carbenes can be generated in both their triplet and sing

69 monstrated that stable singlet electrophilic carbenes can behave as metal surrogates in the activatio

70 choice: the resulting piano-stool ruthenium carbenes can engage a tethered alkene into either cyclop

71 Ligands, especially phosphines and carbenes, can play a key role in modifying and controlli

72 or ylide formation by singlet alpha-carbonyl carbene capture in aprotic nucleophilic solvents (with y

73 strategy, one of the hallmarks of alpha-oxo carbene/carbenoid chemistry, that is, the Wolff rearrang

74 one-electron oxidation of an N-heterocyclic carbene-carbodiimide (NHC-CDI) zwitterionic adduct.

75 fords a transfer of nucleophilicity from the carbene carbon atom to the attached exocyclic moiety, an

76 The divalent carbene carbon centre in cyclic (alkyl)(amino)carbenes (

77 g interest in reactive intermediates such as carbenes, carbon radicals, carbanions, and carbocations.

78 is developed using oxidative N-heterocyclic carbene catalysis.

79 The synthesis of a macrocyclic Ru carbene catalyst for selective cross alkene metathesis i

80 thenium 2,2':6',2"-terpyridine (tpy) pyridyl-carbene catalysts reveals the importance of stereochemic

81 ability to access both enantiomers from the carbene-catalyzed reaction is a powerful strategy that c

82 d 1,4-diketones has been developed through a carbene-catalyzed Stetter reaction of vinylphosphonates

83 lations reveal that this gives unprecedented carbene character to the P-C-O unit, which engages in a

84 arbon atoms of the L->C(2) complex both have carbene character.

85 This approach opens a new horizon for the carbene chemistry to modify silver nanoparticles with va

86 carbenes are relatively new in the field of carbene chemistry; although applications in C-H and X-H

87 as well as to the stability of the secondary carbene complex formed, if metathesis were to take place

88 Here, we report that treatment of a uranium-carbene complex with an organoazide produces a uranium(V

89 er position transforms into a discrete metal carbene complex.

90 cedented structurally characterised arsonium-carbene complex.

91 Copper N-heterocyclic carbene complexes serve as mediators for this transforma

92 ght or oxygen, which is unusual for tungsten carbene complexes.

93 hat leads to the formation of discrete metal carbene complexes.

94 ent herein anionic borate-based bi-mesoionic carbene compounds of the 1,2,3-triazol-4-ylidene type th

95 n as a strategy for the synthesis of Fischer carbene-containing polymers.

96 ne moieties can allow access to unusual free carbene coordination geometries given the proper stabili

97 Cz) roughly a factor of 10 shorter than for (carbene)Cu(Cz) complexes.

98 r modest activation barriers, and the latter carbenes cyclize very easily to 2 H- and 3 H-indazoles,

99 entally demonstrate that the smallest cyclic carbene, cyclopropenylidene, binds even more strongly th

100 .g. as accomplished for cyclopentadienyl and carbene derivatives) and a rewarding collaboration betwe

101 , whereas Rh(2) (S-TPPTTL)(4) works best for carbenes derived from aryldiazoacetates.

102 arboxylates catalyze an Si-H insertion using carbenes derived from diazo compounds where selective fo

103 silyl ethers was achieved using rhodium(II) carbenes derived from N-sulfonyltriazoles and aryldiazoa

104 anometallic complexes since the 1960s, these carbenes did not attract considerable attention until Ar

105 is similar to that of the superelectrophilic carbene difluorovinylidene.

106 esses involving the iron(III) N-heterocyclic carbene (FeNHC) photosensitizer [Fe(phtmeimb)(2)](+) (ph

107 carbenoids leads to the formation of singlet carbenes followed by their trapping via an intramolecula

108 ue-level resolution enabled by IM-MS-coupled carbene footprinting can bridge the gap between structur

109 Carbene footprinting efficiently labels proteinaceous re

110 The established workflow combines carbene footprinting, extended liquid chromatographic se

111 Tricyclo[2.1.0.0(2,5)]pent-3-ylidene is a carbene foreseen to rearrange to pyramidane (c-C(4)H(4))

112 e deprotonated by hydroxide ions, leading to carbenes formation that self-assembled on the electrode'

113 Siloxy carbenes, formed thermally or photochemically from acyl

114 sive mechanism of photochemical formation of carbenes from diazoalkanes has not been proposed.

115 volution toward more challenging heterocycle carbene functionalizations, including C(2)/ C(3) regiose

116 In this transformation, the carbene generated from the triazolium salt using Na(2)CO

117 apping platform that exploits photocatalytic carbene generation to selectively identify protein-prote

118 yst-antibody conjugate to spatially localize carbene generation, we demonstrate selective labeling of

119 ns of the C-H insertion chemistry of rhodium carbenes has become a powerful synthetic method.

120 ursor, but procedures using diazo-free metal carbenes have been developed with significant success.

121 ent species carrying a divalent carbon atom, carbenes have emerged as key reactive intermediates in o

122 d by taking advantage of NHC (N-heterocyclic carbene, here IDipp) coordination to the low-valent phos

123 e the exotic chemistry of novel higher-order carbenes in the gas phase.

124 ending on the involved catalytic system, the carbene insertion can efficiently be driven towards a sp

125 selectively catalyze cyclopropene formation, carbene insertion into a propargylic C-H bond or [3 + 2]

126 on from the T(1) state of acylsilane and the carbene insertion into the B-H bond occurred in a concer

127 Carbene insertion reactions with B-H bonds are a challen

128 Palladium-catalyzed carbene insertion was utilized in a formal synthesis of

129 cleavage of one Fe-C bond, generates an iron-carbene intermediate capable of coordinating N(2).

130 Mechanistic studies reveal that a metal carbene intermediate is not part of the catalytic cycle.

131 c reaction of styrene with the alkenyl-Au(I) carbene intermediate to afford the cis-disubstituted cyc

132 , this transformation does not proceed via a carbene intermediate, nor does it require the presence o

133 ial precursors to generate alpha-imino metal-carbene intermediates and applied in direct C-H function

134 fer direct access to reactive alpha-oxo gold carbene intermediates from benign and readily available

135 ansfer reactions of diazo compounds via free carbene intermediates have emerged as a practical, mild

136 red heme enzymes that can insert fluoroalkyl carbene intermediates into alpha-amino C( sp(3))-H bonds

137 stepwise mechanism proceeds through singlet carbene intermediates which can also participate in bimo

138 generated systems catalyze the insertion of carbenes into the C-H bonds of a range of phthalan deriv

139 al approach that now allows the insertion of carbenes into the Si-H bond of silanes under metal-free

140 on, including whether the singlet or triplet carbene is formed, are probed.

141 e intensified nucleophilicity of the singlet carbene is manifested in quantifiable ways.

142 The alpha-carbonyl carbene is monitored by using a band with solvent-depend

143 ained 4-membered metallacycle bearing a free carbene, is described.

144 Li enolates to a roughly sp(2) type in their carbene keto tautomers, is recognized in one of these pa

145 rinting strategy based on the discovery that carbene labeling produces subresidue peptide isomers and

146 The bulky rhodium carbenes led to highly site-selective functionalization

147 catalyzed by Ni/AlMe(3) and a N-heterocyclic carbene ligand has recently been established.

148 locate the strongly donating N-heterocyclic carbene ligand trans to the site of CO(2) activation.

149 ere synthesized with the tris-N-heterocyclic carbene ligand tris[2-(3-mesitylimidazol-2-ylidene)ethyl

150 lex that contains a sulfonate N-heterocyclic carbene ligand was first reported 15 years ago.

151 nally, pairing the strongly donating pyridyl-carbene ligand with the redox-active tpy ligand proves t

152 e H, Me, and Ph groups from germanium to the carbene ligand.

153 on of the fluorinated pyridine moiety to the carbene ligand.

154 m dyes were used as precursors for mesoionic carbene ligands (Azo-MICs).

155 ommon amide (N-carbazolyl) and two different carbene ligands (i.e., CAAC = (5 R,6 S)-2-(2,6-diisoprop

156 chelating pyridylidene remote N-heterocyclic carbene ligands (rNHCs).

157 ulations on duplex DNA in the presence of Au-carbene ligands indicates a preference for the minor gro

158 ical copper(I) complexes supported by chiral carbene ligands is described.

159 ntaining C(1)-symmetric cyclic (alkyl)(amino)carbene ligands is reported.

160 Two N-heterocyclic carbene ligands provide orthogonal chemoselectivity duri

161 Whereas very restricted mobility of two Au-carbene ligands was found upon binding as a doublet to o

162 of gold complexes containing N-heterocyclic carbene ligands with biological properties.

163 gated bearing nonconventional N-heterocyclic carbene ligands, monoamido-aminocarbene (MAC*) and diami

164 ccess to key precursors of pyridyl-mesoionic carbene ligands.

165 An N-heterocyclic-carbene-ligated 3-benzoborepin with a bridged structure

166 tiple bond to give, after rearrangement, the carbene-ligated Al(III) amide, NacNac'Al(NHTol)(SIMe) (6

167 Reactivity studies of 3 corroborate its carbene-like nature: protonation with [LutH]I results in

168 The crystal structures of the (carbene)M((I))(N-carbazolyl) (M(CAAC)) and (MAC)M((I))(N

169 All six of the (carbene)M(Cz) complexes examined here display high photo

170 ovel, redox-active bipyridyl- N-heterocyclic carbene macrocyclic ligand complexed with nickel, CO(2)

171 B appeared to be possible for the postulated carbene mechanism.

172 on, the first examples of the gold mesoionic carbene mediated [2+2+2] cycloaddition of these enynes w

173 zed Conia ene reaction and an N-heterocyclic carbene-mediated acyloin addition to rapidly fashion its

174 design of the next generation of stable blue carbene-metal-amide emitters.

175 Here we synthesise carbene-metal-amide photoemitters with CF(3)-substituted

176 Carbene-metal-amides are soluble and thermally stable ma

177 Transfers of carbene moieties to heterocycles or cyclic alkenes to ob

178 of gold(i) complexes bearing N-heterocyclic carbene (NHC) and phosphine (PR(3)) ligands.

179 ing was made possible merging N-heterocyclic carbene (NHC) and photoredox catalysis.

180 l molybdenum imido alkylidene N-heterocyclic carbene (NHC) bistriflate and monotriflate monoalkoxide

181 inone methides (aza-o-QMs) by N-heterocyclic carbene (NHC) catalysis has been discovered and explored

182 ediated metalation (AMMM) and N-heterocyclic carbene (NHC) chemistry, a novel C-N bond activation and

183 Iron N-heterocyclic carbene (NHC) complexes have received a great deal of at

184 tom abstraction from a set of N-heterocyclic carbene (NHC) complexes of alkenylboranes bearing two te

185 A series of palladium N-heterocyclic carbene (NHC) complexes of type trans-{(NHC)PdCl(2)L} (L

186 The remarkable resilience of N-heterocyclic carbene (NHC) gold bonds has quickly made NHCs the ligan

187 Although N-heterocyclic carbene (NHC) iridium complexes are promising molecular

188 red, where :C^N is a helicene-N-heterocyclic carbene (NHC) ligand and X=Cl or I.

189 The use of an electron-rich N-heterocycilc carbene (NHC) ligand is effective to inhibit undesired b

190 omplex bearing an unsaturated N-heterocyclic carbene (NHC) ligand, for the first time, products deriv

191 s with varying sterics of the N-heterocyclic carbene (NHC) ligand.

192 ring C(1)- and C(2)-symmetric N-heterocyclic carbene (NHC) ligands were prepared from prochiral NHC p

193 uthenium catalysts with bulky N-heterocyclic carbene (NHC) ligands.

194 c molybdenum imido alkylidene N-heterocyclic carbene (NHC) monotriflate complex with 2-methoxystyrene

195 turated 2,6-diisopropylphenyl N-heterocyclic carbene (NHC) precursors with excellent selectivity (up

196 s relative to their important N-heterocyclic carbene (NHC) predecessors, as recently demonstrated in

197 the reaction proceeds via an N-heterocyclic carbene (NHC) siloxygermylene [(NHC)RGe(OSiHPh(2))].

198 lting from the addition of an N-heterocyclic carbene (NHC) to benzaldehyde triggers a fast deprotonat

199 ans effect of picoline vs the N-heterocyclic carbene (NHC) was quantified through a kinetic analysis

200 N-Heterocyclic carbene (NHC)- and cyclic (alkyl)(amino)carbene (CAAC)-s

201 radicals derived from alkenyl N-heterocyclic carbene (NHC)-boranes bearing ester substituents were re

202 ilable alkenyl triflates with N-heterocyclic carbene (NHC)-boranes in the presence of diisopropyl eth

203 The N-heterocycle carbene (NHC)-catalyzed dual Stetter cascade reaction is

204 An N-heterocyclic carbene (NHC)-catalyzed intramolecular Stetter reaction

205 The reductive coupling of a N-heterocyclic carbene (NHC)-stabilized aryldibromoborane yields a mixt

206 port the use of two polymeric N-heterocyclic carbenes (NHC) (polydentate and monodentate) to stabiliz

207 N-Heterocyclic carbenes (NHC) are nowadays ubiquitous and indispensable

208 from readily available chiral N-heterocyclic carbenes (NHCs) and chiral diamines is disclosed for the

209 The use of N-heterocyclic carbenes (NHCs) as ancillary ligands has made substantia

210 N-Heterocyclic carbenes (NHCs) catalyzing aza-Claisen rearrangement of

211 s such as bulky phosphines or N-heterocyclic carbenes (NHCs) has enabled reactions of unactivated alk

212 unctional theory computations.N-heterocyclic carbenes (NHCs) have been applied as ancillary ligands i

213 Although N-heterocyclic carbenes (NHCs) have been known as ligands for organomet

214 N-heterocyclic carbenes (NHCs) have been widely utilized for the format

215 Although N-heterocyclic carbenes (NHCs) have demonstrated outstanding potential

216 dinating dianionic carboranyl N-heterocyclic carbenes (NHCs) to create organometallic -ate complexes

217 N-Heterocyclic carbenes (NHCs) were recently shown to form self-assembl

218 nt in functionalizing gold by N-heterocyclic carbenes (NHCs), a promising alternative ligand class re

219 disubstituted imidazolylidene N-heterocyclic carbenes (NHCs), where the 4,5-substituents are Me, H, o

220 in-2-ylidenes, the well-known N-heterocyclic carbenes (NHCs).

221 resulting in diffusion of a highly reactive carbene nucleophile away from the POI.

222 ly, it drives further exploration of various carbenes on metal surfaces.

223 -diisopropylphenyl (Dip); D = N-heterocyclic carbene or 4-dimethylaminopyridine, DMAP), which X-ray c

224 leads to the formation of either MCH(2) (+) carbene or HMCH(+) carbyne hydride structures, the obser

225 ration of surface modification with a stable carbene other than NHC; more broadly, it drives further

226 nt can be readily realized by alpha-oxo gold carbenes oxidatively generated from TBS-terminated alkyn

227 e research efforts, the synthesis of iron PC(carbene)P pincer complexes has so far remained elusive.

228 Many fundamental properties of carbenes, particularly basicity, remain poorly understoo

229 fin monomers; however, controlled and living carbene polymerization has been a long-standing challeng

230 Carbene polymerization provides polyolefins that cannot

231 mers, which polymerize ethyl diazoacetate, a carbene precursor in a controlled and quasi-living manne

232 is enables the use of [1.1.1]propellane as a carbene precursor in cyclopropanations of a range of fun

233 mechanophore built around an N-heterocyclic carbene precursor proceeds with the rupture of a C-C bon

234 cally involve the formation of a diazo-based carbene precursor, but procedures using diazo-free metal

235 Although diazoalkanes are important carbene precursors in organic synthesis, a comprehensive

236 N-sulfonyltriazoles and aryldiazoacetates as carbene precursors.

237 Here, the imidazolium-carbenes preferentially react with the disulfide bond, b

238 )(2)Be](+*) (2) [CAAC = cyclic (alkyl)(amino)carbene], prepared by oxidation of a zero-valent berylli

239 sertion reactions with donor/donor and donor carbenes, providing context for future developments in t

240 two N-(2-pyridyl)-substituted N-heterocyclic carbene (PyNHC) ligands in a bidentate fashion in additi

241 1-Substituted derivatives of the carbene (R != H) are sensitive to sigma inductive effect

242 -mediated pathway for singlet alpha-carbonyl carbene reaction with alcohols (ethanol or tert-butanol)

243 Finally, carbene rearrangements via 1,2-C atom shift or enyne fra

244 The index described previously (carbene relative energy of formation) has been extended

245 es and their tendency for dimerization, free carbenes represent one of the foremost obscured classes

246 between catalysts containing large and small carbenes results more from stabilizing intramolecular no

247 The carbene's most striking feature is its :CH-group.

248 jugation, can play a significant role in the carbene-selenium (77) Se NMR chemical shift, thus trigge

249 (i.e., stereodivergence) of a new-to-nature carbene Si-H insertion reaction.

250 t = benzene dithiolate, NHC = N-heterocyclic carbene) sites.

251 ought to proceed via the formation of Rh(II) carbene species followed by interaction with the Lewis b

252 The new gamma-keto carbene species under study belong to a subclass of acyc

253 ment, one which involves the intermediacy of carbene species.

254 Carbene stabilization enthalpy (CSE) values were also de

255 double bond, was achieved by reduction of a carbene-stabilized 1,1'-bis(dihaloboryl)ferrocene.

256 represents the unprecedented utilization of carbene-stabilized disilicon (1) as a silicon-transfer a

257 Reaction of carbene-stabilized disilicon (1) with the lithium-based

258 The tungsten carbene subunits were readily incorporated into block co

259 r level and expanded to higher-order homolog carbenes such as butadiynylcyclopropenylidene and triple

260 sion that other phosphine and N-heterocyclic carbene, such as P (n)BuAd(2) and IMes, can be used as a

261 s-Block metal carbenoids are carbene synthons and applied in a myriad of organic tran

262 signed redox-active Au(I) bis-N-heterocyclic carbene that induces ICD both in vitro and in vivo.

263 Hence, drug molecules such as gold (Au)-carbene that stabilize G-quadruplexes may also interfere

264 insight into the properties of this class of carbenes, the thermodynamic stabilities of a series of k

265 alized on the surface by a furyl-substituted carbene through an insertion reaction.

266 ient rhodium-catalyzed insertion of azavinyl carbenes to C3-H bond of indole followed by base-mediate

267 bicyclic aziridines and rhodium-bound vinyl carbenes to form complex dehydropiperidines in a highly

268 ts of intra/intermolecular azo coupling, and carbenes to give pyrrole-containing insertion products i

269 d stereoselective intermolecular transfer of carbenes to olefins, heterocycles, aldehydes, and amines

270 highlight the ability of these Fischer-type carbenes to participate in cascade alternating ring-open

271 ring expansion of aromatic heterocycles via carbene transfer by any enzyme.

272 The carbene transfer from an optically pure Cu complex to a

273 ed from sperm whale myoglobin that exploit a carbene transfer mechanism for the asymmetric synthesis

274 reactions of onium ylides via gold catalyzed carbene transfer reactions are relatively unexplored.

275 Only recently, visible light-promoted carbene transfer reactions of diazo compounds via free c

276 Transition-metal-catalyzed carbene transfer reactions, involving diazo compounds an

277 rogress has been achieved in metal-catalyzed carbene transfer reactions.

278 ment of metalloprotein catalysts for abiotic carbene transfer reactions.

279 lving a cytochrome P450 for highly efficient carbene transfer to indoles, pyrroles, and cyclic alkene

280 rry out efficient cyclopropene synthesis via carbene transfer to internal alkynes.

281 Not only is this a report of carbene transferase activity in a completely de novo pro

282 However, carbene transferases accepting heterocyclic substrates a

283 tunable active-site geometries, hemoprotein "carbene transferases" could provide an alternative to tr

284 fective chiral catalyst for triazole-derived carbene transformations, whereas Rh(2) (S-TPPTTL)(4) wor

285 Modeling of the carbene, using the (U)MPWB1K/cc-pVTZ//(U)MPWB1K/6-311G(d

286 nglet ethynylcyclopropenylidene (c-C(5)H(2)) carbene-via the elementary reaction of the simplest orga

287 The charge-tagged carbene was generated in situ in a tandem mass spectrome

288 The reactivity of 2 with stable carbenes was also explored.

289 dimNHCGe (5, dimNHC = diimino N-heterocyclic carbene) was successfully prepared via the reduction of

290 he enhanced stability imparted by ambiphilic carbenes, we report and rationalize the absolute templat

291 amic stabilities of a series of known siloxy carbenes were explored on the basis of hydrogenation ent

292 rates were then exposed to an N-heterocyclic carbene, whereupon intramolecular Stetter reaction proce

293 ohols, as it requires the interaction of the carbene with a protic solvent molecule being part of a h

294 r the reaction of the singlet alpha-carbonyl carbene with methanol shows that the enol forms without

295 The reaction of N-heterocyclic carbene with N-tBu-substituted pyrrolinium triflate affo

296 indicate that 3 is best described as a free carbene with partial Ti-C(beta) bonding that results fro

297 tathesis catalyst bearing two N-heterocyclic carbenes with an oxidizing pyrylium photocatalyst afford

298 s-phase chemistry of preparing two prototype carbenes with distinct multiplicities-triplet pentadiyny

299 ands, 23 bidentate P,P-donor ligands, and 30 carbenes, with a view to providing a useful resource for

300 l (using dispersion-corrected DFT) on siloxy carbenes (X-C-OSiR(3), singlet and triplet state), oxoca