ライフサイエンスコーパス: carbogen

1 (sO2) levels and BOLD signal in response to carbogen.

2 inued with air (for controls) or switched to carbogen.

3 ugh the vascular central retinal response to carbogen, 0 to 1 mm from the optic nerve, was greater th

4 e vascular midperipheral retinal reaction to carbogen, 1 to 2 mm from the optic nerve, was as low as

5 ous delta PO2 during the breathing of either carbogen (130 +/- 9 mm Hg, mean +/- SEM; n = 5) or 100%

6 retinal vitreous delta PO2 were found during carbogen (164 +/- 23 mm Hg; n = 3) and oxygen breathing

7 ent three episodes of air and 100% oxygen or carbogen (5% CO(2) and 95% O(2)) breathing.

8 shifts in brain pH through the breathing of carbogen (5% CO(2)/95% O(2)) reduces seizure susceptibil

9 paring paired images acquired during air and Carbogen (7% CO2 and 93% oxygen) breathing.

10 ht fasting, animals, breathing either air or carbogen (95% O(2) + 5% CO(2)), were intravenously admin

11 Using EPRI and an air/carbogen (95% O(2) plus 5% CO(2)) breathing cycle, we vi

12 Alternating breathing cycles with air or carbogen (95% O(2) plus 5% CO(2)) distinguished higher a

13 d while the host first breathed air and then carbogen (95% O(2), 5% CO(2); n = 16).

14 Oxygenation of tumors was enhanced on carbogen (95% O(2)/5% CO(2)) inhalation.

15 g were performed to assess tumor response to carbogen (95% O2, 5% CO2) in mice with head and neck tum

16 MRI and a 2-minute carbogen (95% O2/5% CO2) inhalation challenge (see ref.

17 oxygenation response (deltaPO2, mm Hg) to a carbogen (95% O2/5% CO2) inhalation challenge.

18 ra serrata to inferior ora serrata) during a carbogen (95% O2/5% CO2) inhalation challenge.

19 creased when the tumor-bearing mice breathed carbogen (95% O2:5% CO2).

20 tic resonance imaging (fMRI) technique and a carbogen (a gas mixture of 5% carbon dioxide and 95% oxy

21 Carbogen alone provided minimal sensitization.

22 DDFP plus carbogen appears to completely reverse the hypoxic cell

23 nstrate that male and female mice exposed to carbogen are fully protected from thermogenic-triggered

24 duction in the tumor hemodynamic response to carbogen at PAI (P = .030).

25 Carbogen-based functional imaging with PAI and BOLD MR i

26 Additionally, mild hyperthermia followed by carbogen breathing further increased the tumor pO2 and i

27 The hyaloidal perfusion response to carbogen breathing in the newborn rats decreased as foll

28 BOLD retinal responses to oxygen and carbogen breathing in unanesthetized humans can be relia

29 d that mild hyperthermia in combination with carbogen breathing is potentially useful to reoxygenate

30 Retinal deltaPO(2) during carbogen breathing of the 40/15 animals that did not hav

31 hat in the normal adult and newborn rat eye, carbogen breathing oxygenates the inner retina better th

32 sing the oxygen tension in the brain through carbogen breathing reversed the neuroprotective effects

33 Carbogen breathing significantly decreased (18)F-FDG acc

34 deltaPO(2) was 61% greater (P < 0.05) during carbogen breathing than during oxygen breathing.

35 Retinal DeltaPO(2) during carbogen breathing was also measured in PKCbeta knockout

36 In C mice, retinal DeltaPO(2) during carbogen breathing was significantly greater (P < 0.05)

37 In D mice, DeltaPO(2) during carbogen breathing was significantly lower than normal i

38 Functional hyaloidal volumes during carbogen breathing were not significantly different (P >

39 no longer had NV, retinal deltaPO(2)s during carbogen breathing were significantly (P < 0.05) lower t

40 This enhanced uptake was abrogated by carbogen breathing, indicating that in the absence of ph

41 icroscopic peritoneal tumors were reduced by carbogen breathing.

42 als with enhanced pre-PDT oxygenation due to carbogen breathing.

43 room air combined with either 100% oxygen or carbogen breathing.

44 DDFP plus carbogen caused dramatic radiosensitization, and the rad

45 ent of the retinal oxygenation response to a carbogen challenge appears to be a powerful new and noni

46 ssel density and vascular reactivity (VR) to carbogen challenge of HD mice were monitored by 3D Delta

47 lation (that is, its ability to respond to a carbogen challenge) and quantitatively comparing the fun

48 The present data show the applicability of carbogen-challenge functional MRI to the study of retina

49 Carbogen-challenge MRI seems to be a useful tool for ass

50 t significantly different between oxygen and carbogen challenges (P > 0.05).

51 ower sensitivity regions, which responded to carbogen, corresponding to cycling hypoxia and chronic h

52 Carbogen-enhanced MRI appears to be a powerful new and n

53 It employs the carbogen gas bubbles to drive the flow circulation in a

54 Breathing carbogen gas significantly decreased the hypoxia level m

55 Carbogen gas-challenge BOLD MR imaging can depict hepati

56 mic response to a systemic perturbation with carbogen gas; and (v) frequency domain analysis of hemod

57 d FAIR MRI revealed gradually impaired VR to carbogen in HD mice.

58 not reveal any difference in baseline R2* or carbogen-induced change in R2*.

59 dies exhibited excellent correlation between carbogen-induced changes in SO(2) and pO(2) of radiation

60 baseline tumor R2* (r = -0.54, P = .03) and carbogen-induced DeltaR2* (r = 0.56, P = .02), demonstra

61 del of breast cancer, baseline tumor R2* and carbogen-induced DeltaR2* are predictive imaging biomark

62 bited wide heterogeneity in the magnitude of carbogen-induced reduction in R2*, an emerging imaging b

63 Carbogen inhalation and oral corticosteroids were also g

64 before (room air [ra]) and during a 4-minute carbogen inhalation challenge in five groups: control Sp

65 icacy, was measured by MRI during a 2-minute carbogen inhalation challenge in four groups: control ra

66 that magnetic resonance imaging (MRI) and a carbogen inhalation challenge provides important diagnos

67 l response of the hyaloidal circulation to a carbogen inhalation challenge was noninvasively evaluate

68 ional magnetic resonance imaging (MRI) and a carbogen inhalation challenge was used to measure retina

69 rior correlation in the temporal response to carbogen inhalation for the experimental animals than in

70 Carbogen inhalation showed significantly higher signal i

71 Percent changes due to oxygen or carbogen inhalation versus air were tabulated for whole-

72 Carbogen inhalation-enhanced MR microangiography signal

73 asurements were made during air, oxygen, and carbogen inhalation.

74 1.3% (N = 11 trials from five subjects) for carbogen inhalation.

75 etinal oxygen tension (Delta PO(2)) during a carbogen-inhalation challenge.

76 ikely basis of seizure suppression caused by carbogen-mediated acidification.SIGNIFICANCE STATEMENT B

77 Both carbogen-mediated seizure protection and the reduction i

78 ucleotides reduced the protective effects of carbogen on seizure susceptibility.

79 Systemic levels of hyperoxia during carbogen or 100% oxygen breathing were not significantly

80 magnetic resonance imaging (MRI) and either carbogen or 100% oxygen inhalation challenge in C57BL/6J

81 ne anesthesia with the animals breathing O2, carbogen, or air, median PO2 values increased significan

82 genation change (measured using ra and first carbogen periods [t1 - ra]) and the next 2-minute change

83 inute change (assessed with first and second carbogen periods [t2-t1]) for superior and inferior hemi

84 % oxygen breathing (n = 5) before a 2-minute carbogen provocation.

85 on intravenously and retinal DeltaPo2 during carbogen provocation.

86 hyaloidal circulation perfusion response to carbogen, the functional spatial extent of the hyaloidal

87 In vivo hemodynamic response to carbogen was characterized by a significant increase in

88 In the ROP group, the response to carbogen was lower (P < 0.05) at every distance from the