ライフサイエンスコーパス: carbohydrate recognition domain

1 ns (i.e., N-terminal, collagen, and neck and carbohydrate recognition domains).

2 18 highly conserved aa residues known as the carbohydrate recognition domain.

3 mic domain, the transmembrane region and the carbohydrate recognition domain.

4 teine residues required to form the standard carbohydrate recognition domain.

5 linked glucosyl trisaccharides into the SP-D carbohydrate recognition domain.

6 , which, like SP-D, contains a C-type lectin carbohydrate recognition domain.

7 binding through the mannose-binding protein carbohydrate recognition domain.

8 e inhibitors of galectin-3, which target the carbohydrate recognition domain.

9 ntibodies specifically targeting the DC-SIGN carbohydrate recognition domain.

10 bone assignment of its active, calcium-bound carbohydrate recognition domain.

11 get its beta-galactoside-binding site in the carbohydrate recognition domain.

12 C-SIGNR to promote WNV infection maps to its carbohydrate recognition domain.

13 , a collagenous domain, a neck region, and a carbohydrate recognition domain.

14 and involve binding to the trimeric, C-type carbohydrate recognition domain.

15 avage to a highly conserved subregion of the carbohydrate recognition domain.

16 ylation sites as well as a C-terminal C-type carbohydrate-recognition domain.

17 typical features of the C-type animal lectin carbohydrate-recognition domain.

18 the carboxyl-terminal half representing the carbohydrate-recognition domain.

19 nal level by stabilizing p21 protein via the carbohydrate-recognition domain.

20 ck the transmembrane region or have modified carbohydrate recognition domains.

21 for beta-galactosides and by their conserved carbohydrate recognition domains.

22 th immune- or clearance receptors containing carbohydrate recognition domains.

23 -galactoside-binding proteins with conserved carbohydrate recognition domains.

24 ive selection and amino acid replacements in carbohydrate-recognition domains.

25 terial growth through AG-binding property of carbohydrate-recognition domain 2.

26 n protein of the mannose receptor containing carbohydrate recognition domains 4-7 and a full-length s

27 C-type carbohydrate-recognition domain 4 (CRD4) of the receptor

28 domain of mincle, beyond the minimal C-type carbohydrate recognition domain, also constrains the way

29 a-galactoside lectins containing a conserved carbohydrate recognition domain and a separate putative

30 selection has been acting on residues in the carbohydrate recognition domain and dimerization interfa

31 We found that the N-terminal carbohydrate recognition domain and linker peptide contr

32 The crystal structure of the trimeric carbohydrate recognition domain and neck domain of SP-A

33 ivity, indicating the N-terminal domain is a carbohydrate recognition domain and the C-terminal domai

34 n culture supernatant retains the N-terminal carbohydrate recognition domain and the epidermal growth

35 fold distantly related to the C-type lectin carbohydrate recognition domain and the hyaluronan-bindi

36 d simultaneously both polysaccharide via the carbohydrate recognition domains and sulfated oligosacch

37 ed inhibition of HCMV was dependent upon its carbohydrate recognition domains and thus dependent on g

38 lactose, indicating that CL-L1 binds via its carbohydrate-recognition domain and has ligand specifici

39 starting from two crystal structures for its carbohydrate-recognition domain and its triple helical r

40 inding site that is characteristic of C-type carbohydrate recognition domains, and the GlcNAc and gal

41 served mode of galactose binding in a C-type carbohydrate-recognition domain bearing the Glu-Pro-Asn

42 ositions in the amino acid sequence of their carbohydrate recognition domains, binds Siaalpha2,6GalNA

43 apable of binding B. burgdorferi through its carbohydrate recognition domains, but in vitro complemen

44 tion frame changes near the beginning of the carbohydrate recognition domain, causing premature termi

45 hniques, we show that MVL contains two novel carbohydrate recognition domains composed of four non-co

46 tandem-repeat galectin characterized by two carbohydrate recognition domains connected by a linker-p

47 was a tandem repeat galectin containing two carbohydrate recognition domains connected by a unique p

48 nt constructs with galectin-9 and galectin-1 carbohydrate recognition domains connected by different

49 ia a secondary binding pocket within the MGL carbohydrate recognition domain containing the His(259)

50 oside binding protein, contains a C-terminal carbohydrate recognition domain (CRD) and an N-terminal

51 nd beta-galactosides through their conserved carbohydrate recognition domain (CRD) and can induce agg

52 LGALS15 contains a predicted carbohydrate recognition domain (CRD) as well as LDV and

53 The LMAN1 carbohydrate recognition domain (CRD) binds to both glyc

54 -1, are isolated as dimers and have a single carbohydrate recognition domain (CRD) in each monomer, w

55 efine an extended binding site in the C-type carbohydrate recognition domain (CRD) of bovine mincle t

56 The structure of DENV in complex with the carbohydrate recognition domain (CRD) of DC-SIGN was det

57 n the splenic marginal zone, blockade of the carbohydrate recognition domain (CRD) of SIGN-R1, or gen

58 Binding takes place via the carbohydrate recognition domain (CRD) of SP-D.

59 The carbohydrate recognition domain (CRD) of surfactant prot

60 ed Fc (sFc) has been reported to bind to the carbohydrate recognition domain (CRD) of the cell-surfac

61 n characteristic amino acid sequences in the carbohydrate recognition domain (CRD) of the polypeptide

62 is a hexameric transmembrane protein with a carbohydrate recognition domain (CRD) on the ER luminal

63 These interactions involve binding of the carbohydrate recognition domain (CRD) to LPS oligosaccha

64 By expression cloning, the carbohydrate recognition domain (CRD) was identified wit

65 (48% for the whole molecule and 77% for the carbohydrate recognition domain (CRD)) with the bovine s

66 bonds with Cys(29) and with Cys(57) near the carbohydrate recognition domain (CRD), whereas N-ethylma

67 e at 1645 cm(-1) suggested to arise from the carbohydrate recognition domain (CRD).

68 rotein gp140 and whole HIV particles via the carbohydrate recognition domain (CRD).

69 ding of glycoconjugates to the C-type lectin carbohydrate recognition domain (CRD).

70 is mediated by interactions between the SP-D carbohydrate recognition domains (CRD) and glycans displ

71 coupled to the neck recognition domains and carbohydrate recognition domains (CRD) of MBL or conglut

72 ar glycoprotein containing collagen-like and carbohydrate recognition domains (CRD), binds P. carinii

73 he recognition of glycan motifs by its three carbohydrate recognition domains (CRD).

74 in higher animals and both are composed of a carbohydrate-recognition domain (CRD) and a collagenous

75 extracellular region consisting of a C-type carbohydrate-recognition domain (CRD) and a neck region

76 of each receptor contains a membrane-distal carbohydrate-recognition domain (CRD) and forms tetramer

77 The carbohydrate-recognition domain (CRD) in dectin-2 is lin

78 he three-dimensional structure of the C-type carbohydrate-recognition domain (CRD) of MBP-C using x-r

79 release of ligands from the Ca(2+)-dependent carbohydrate-recognition domain (CRD) of the hepatic asi

80 dized lipoproteins it also contains a C-type carbohydrate-recognition domain (CRD) that interacts wit

81 demonstrated that replacement of the DC-SIGN carbohydrate-recognition domain (CRD) with that of L-SIG

82 a hyaluronidase, (iv) a protein containing a carbohydrate-recognition domain (CRD), and (v) a RGD-con

83 drate-recognition events through a conserved carbohydrate-recognition domain (CRD).

84 mbinant fragment of conglutinin's C-terminal carbohydrate-recognition domain (CRD).

85 w density lipoproteins but contains a C-type carbohydrate-recognition domain (CRD).

86 While the carbohydrate-recognition domains (CRD) exist as monomers

87 inal GalNAc-4-SO4, whereas calcium-dependent carbohydrate recognition domains (CRDs) account for bind

88 I/MPR contains 15 repeating domains; the two carbohydrate recognition domains (CRDs) have been locali

89 ectin (MsaFBP32) that consists of two F-type carbohydrate recognition domains (CRDs) in tandem.

90 domains of rat SP-D (rSP-D) and the neck and carbohydrate recognition domains (CRDs) of bovine conglu

91 The carbohydrate recognition domains (CRDs) of human serum m

92 The carbohydrate recognition domains (CRDs) of lung collecti

93 Floating on the surface of DectiSomes, the carbohydrate recognition domains (CRDs) of these CTLs fo

94 , a tandem repeat galectin, has two distinct carbohydrate recognition domains (CRDs) that may cross-l

95 ortion of the receptor includes eight C-type carbohydrate recognition domains (CRDs), of which one, C

96 toside-binding animal lectins with conserved carbohydrate recognition domains (CRDs).

97 fibrillar collagen-like regions and globular carbohydrate recognition domains (CRDs).

98 fibrillar collagen-like regions and globular carbohydrate recognition domains (CRDs).

99 at combine to enhance the affinity of single carbohydrate-recognition domains (CRDs) for glycoprotein

100 nal lectin-like domain that resembles C-type carbohydrate-recognition domains (CRDs) found in many gl

101 Carbohydrate-recognition domains (CRDs) in the glycan-bi

102 ectin array containing all of the cow C-type carbohydrate-recognition domains (CRDs), a human array d

103 te the search for competitive inhibitors for carbohydrate-recognition domains (CRDs).

104 the first information on the dynamics of the carbohydrate recognition domain, demonstrating that it i

105 nant protein consisting of only the neck and carbohydrate recognition domain did not augment metallop

106 a conformational change that repositions the carbohydrate-recognition domains during ligand binding.

107 lectin (BgGal) protein of 32 kDa possessed 2 carbohydrate recognition domains, each displaying 6 of 8

108 nslation is expected to terminate within the carbohydrate recognition domain encompassing exons 4, 5,

109 the N-terminal Gly/Pro repeat domain and the carbohydrate recognition domain (exons 3 and 4).

110 owing putative structural elements: a C-type carbohydrate recognition domain, five EGF-like domains,

111 Trimeric neck plus carbohydrate recognition domains from human SP-D (hNCRD)

112 Carbohydrate recognition domains from the macrophage rec

113 Crystal structures of the carbohydrate-recognition domain from human langerin boun

114 nal (GST-Gal-9N) and C-terminal (GST-Gal-9C) carbohydrate recognition domains greatly improved protei

115 anization clearly established a role for the carbohydrate recognition domain in binding to conidia.

116 The C-type carbohydrate recognition domain in the extracellular por

117 tition and Ca(2+) chelation, implicating the carbohydrate recognition domain in the interaction.

118 pneumoniae lipids, directly implicating the carbohydrate recognition domain in the interaction.

119 galectins, galectins-4 and -6, each with two carbohydrate recognition domains in the same peptide.

120 Aspergillus fumigatus partially through the carbohydrate-recognition domain in a Ca(2+)-independent

121 Crystallographic analysis of this mutant carbohydrate-recognition domain in complex with N-acetyl

122 l in which the different dispositions of the carbohydrate-recognition domains in DC-SIGN and DC-SIGNR

123 racentrifugation experiments showed that the carbohydrate-recognition domains in the MBL dimer, trime

124 ligands enhances the engagement of multiple carbohydrate-recognition domains in the receptor oligome

125 Its carboxyl-terminal carbohydrate-recognition domain is essential for this ef

126 ide of 244 amino acids containing a putative carbohydrate recognition domain motif at the COOH-termin

127 ptide of 209 amino acids containing a single carbohydrate recognition domain motif in the COOH termin

128 Trimeric neck-carbohydrate recognition domains (NCRDs) of rat and huma

129 The interdomain carbohydrate recognition domain-neck angle is significan

130 Within their extracellular carbohydrate recognition domains, NKG2C and NKG2E share

131 bulin, and antibody against a peptide in the carbohydrate recognition domain of ASGP-R but not preimm

132 tion of SM30 proteins is very similar to the carbohydrate recognition domain of C-type lectin protein

133 lonal antibodies (MAbs) directed against the carbohydrate recognition domain of DC-SIGN.

134 interacts with immobilized Gal-3 through the carbohydrate recognition domain of Gal-3 during eosinoph

135 ain that is predicted to position the intact carbohydrate recognition domain of Gal-3TM1 on the exter

136 eted of both galectins; and (v) although the carbohydrate recognition domain of galectin-3 (or galect

137 rlying differences in ligand affinity to the carbohydrate recognition domain of galectin-3, using a c

138 s this critical challenge with the PEGylated carbohydrate recognition domain of human galectin-3 (Gal

139 Herein, we studied the carbohydrate recognition domain of Langerin, a C-type le

140 expression of CD4 (domains 1 and 2) and the carbohydrate recognition domain of mannose binding lecti

141 pdmH1N1 and H9N2/G1 viruses, likely via the carbohydrate recognition domain of MBL.

142 essed by ELISA for their ability to bind the carbohydrate recognition domain of rMBP.

143 pendent complexes of the C-terminal neck and carbohydrate recognition domain of SP-A with d-mannose,

144 ain is dependent on the glycosylation of the carbohydrate recognition domain of SP-A.

145 In addition, the neck + carbohydrate recognition domain of SP-D was necessary an

146 HNPs were found to bind to the neck and/or carbohydrate recognition domain of SP-D.

147 y role in the binding of a glycolipid to the carbohydrate recognition domain of the lectin.

148 for the disaccharide, lactose, bound to the carbohydrate recognition domain of the mammalian lectin,

149 A model of the carbohydrate recognition domain of the serum form of man

150 ular disulfide bonds present in hIntL-1, the carbohydrate recognition domain of XEEL (XEELCRD) forms

151 s, and determined whether PSG1 binds to both carbohydrate recognition domains of GAL-9.

152 Knowledge about carbohydrate recognition domains of galectins, formerly

153 he activities of recombinant trimeric neck + carbohydrate recognition domains of human surfactant pro

154 nfirmed the interaction of ADAMTS13 with the carbohydrate recognition domains of MR.

155 nteracts with the carboxyl-terminal neck and carbohydrate recognition domains of SP-D, inhibited the

156 ng data indicates that lactose binds the two carbohydrate recognition domains of the gal-1 dimer with

157 s of these domains with the sequences of the carbohydrate recognition domains of various vertebrate C

158 amine have been inserted into the homologous carbohydrate-recognition domain of a mannose-binding pro

159 coded the cysteine scaffold that defines the carbohydrate-recognition domain of mammalian CTLs.

160 corresponding serine residue in the modified carbohydrate-recognition domain of mannose-binding prote

161 oined at an N-terminal hub clarified how the carbohydrate-recognition domain of MBL binds to pathogen

162 regions of MBP have been introduced into the carbohydrate-recognition domain of MBP.

163 indicating that Lf bound at or very near the carbohydrate-recognition domain of RHL-1.

164 e invariant residues in the highly conserved carbohydrate-recognition domain of the protein and are p

165 Regions of the carbohydrate-recognition domain of the receptor believed

166 Crystal structures of carbohydrate-recognition domains of DC-SIGN and of DC-SI

167 ce of one or more tryptophan residues in the carbohydrate-recognition domains of each galectin.

168 The structures of the ligand-binding C-type carbohydrate-recognition domains of selectin cell adhesi

169 t 32 A) that they can interact with multiple carbohydrate recognition domains on oligomeric lectins s

170 pendent on correct disposition of the C-type carbohydrate-recognition domains projected at the C-term

171 complexes with the unliganded SP-A neck and carbohydrate recognition domain revealed an unexpected l

172 er fragment containing the trimeric neck and carbohydrate recognition domains (SP-D NCRD).

173 Thus, carbohydrate recognition domain specificity, presentatio

174 mine to compete for binding to this modified carbohydrate-recognition domain suggest that it is a goo

175 ins are a family of lectins with a conserved carbohydrate recognition domain that interacts with beta

176 , which is required for accessibility of the carbohydrate recognition domain to ligands.

177 FGF-mediated angiogenesis by binding via its carbohydrate recognition domain, to the GnTV synthesized

178 However, we found that the C-terminal carbohydrate recognition domain was the primary determin

179 nica), which possesses four tandemly arrayed carbohydrate recognition domains, was previously shown t

180 into a high affinity (K(d) = 0.3 +/- 0.1 nm) carbohydrate-recognition domain whereas the domain 3 alo

181 a homodimer by self-association through its carbohydrate recognition domain, whereas, in the presenc

182 It consists of two carbohydrate recognition domains, which is similar to th

183 r on hepatocytes and that it binds Lf at its carbohydrate-recognition domain yet in a galactose-indep