ライフサイエンスコーパス: carbon skeleton

1 anone moieties, kallosin A is based on a new carbon skeleton.

2 favors the formation of the final hopanoids carbon skeleton.

3 tene ring-opening has a distinctly nonplanar carbon skeleton.

4 tions onto an unsaturated, nonfunctionalized carbon skeleton.

5 e a convergent elaboration of the 17-isoLGE4 carbon skeleton.

6 unprecedented tetracylic anvilane terpenoid carbon skeleton.

7 atalyze key steps in establishing the sterol carbon skeleton.

8 natural products featuring a 6-7-5 tricyclic carbon skeleton.

9 an unprecedented 6/6/5/6/7-fused pentacyclic carbon skeleton.

10 another marine alkaloid bearing a different carbon skeleton.

11 o a reversible electrocyclic reaction of its carbon skeleton.

12 in, which catalyzed cleavage of the flavonol carbon skeleton.

13 mn and separates FAMEs based solely on their carbon skeleton.

14 the degraded "secoansellane" sesterterpenoid carbon skeleton.

15 ighly convergent single-step assembly of the carbon skeleton.

16 cleaving mechanism with rearrangement of its carbon skeleton.

17 ation prior to the formation of the bicyclic carbon skeleton.

18 structures, DPT shows a curved pi-conjugated carbon skeleton.

19 mplex with polycyclic, stereochemically rich carbon skeletons.

20 molecules of interest are based primarily on carbon skeletons.

21 omiscuity allows access to new sesquiterpene carbon skeletons.

22 ss to distinct 1,2,3 triheterofunctionalized carbon skeletons.

23 ed support for a proposed genesis of the new carbon skeletons.

24 e, and 23,24-dinorisodhilirane meroterpenoid carbon skeletons.

25 imilation with the anaplerotic production of carbon skeletons.

26 and entail notable changes in the molecule's carbon skeleton(8-12).

27 e a cluster of compounds composed of a C(18) carbon skeleton, a known but heretofore unnamed type, wh

28 lex dimeric compounds representing two novel carbon skeletons, along with an additional eight new com

29 ) involves an extensive rearrangement of the carbon skeleton and a NADPH-dependent reduction.

30 leads to rapid construction of the tricyclic carbon skeleton and establishes the trans-dimethyl geome

31 give species with electron deficiency in the carbon skeleton and negative charge at the oxygen end th

32 duct possessing a unique 6/4/5/5 tetracyclic carbon skeleton and seven contiguous stereocenters, incl

33 ad to, respectively, the 6,6,6,5-tetracyclic carbon skeleton and the 6,6,6,6,5-pentacyclic hopanoids.

34 pene-benzoate macrolides represent two novel carbon skeletons and add to the 10 previously reported b

35 eeds rely on storage oil breakdown to supply carbon skeletons and energy for early seedling growth, a

36 redicted in the former, primarily to provide carbon skeletons and energy for protein synthesis.

37 e life cycle of many plants by providing the carbon skeletons and energy that drive postgerminative g

38 ose to supply non-photosynthetic organs with carbon skeletons and energy.

39 adipose tissue and skeletal muscle supplies carbon skeletons and enthalpy for inflammatory and immun

40 Fluorocarbons, organic molecules with carbon skeletons and fluorine "skins", differ fundamenta

41 metabolism including supply of biosynthetic carbon skeletons and reducing power.

42 yclo[4.1.0]heptatrienyl-1-carbenes 54 and to carbon-skeleton and hydrogen rearrangements of anthryldi

43 of dehydration/carbonization of citric acid (carbon skeleton) and urea (nitrogen dopant) as source ma

44 tonide alkylations were used to assemble the carbon skeleton, and a simple modification of the strate

45 Amines containing bridged bicyclic carbon skeletons are desirable building blocks for medic

46 rely on efficient distribution of energy and carbon skeletons between organs in the form of sugars.

47 r group leading to a change in the degree of carbon skeleton branching.

48 aration plane, while the FAMEs with the same carbon skeleton but differing in the number, geometric c

49 Terpenoid synthases create diverse carbon skeletons by catalyzing complex carbocation rearr

50 Carbon atoms in the graphitic carbon skeleton can be replaced by heteroatoms with diff

51 trates to generate the enormous diversity of carbon skeletons characteristic of the terpenoid family

52 an unprecedented 7/10/6-tricyclic dilactone carbon skeleton composed of dimethylcyclodecatriene flan

53 ion pattern at the radical center but not in carbon skeleton confirm that X = H is indeed the better

54 well as the construction of complex bicyclic carbon skeletons containing up to four contiguous stereo

55 rodimers with a unique 5/6/6/6/5 pentacyclic carbon skeleton, designated as bipentaromycins A-F.

56 pathway to generate reducing equivalents and carbon skeletons during preferential excitation of photo

57 formation of ampelopsin F and pallidol-type carbon skeletons (e.g., 4,3',4'-trimethoxystilbene).

58 es for encapsulating iodine while the porous carbon skeleton facilitates redox reactions of iodine an

59 gulator of sulfur assimilation and forms the carbon skeleton for Cys biosynthesis.

60 eamination in plants, is conscription of its carbon skeleton for lignin, suberin, flavonoid, and rela

61 Malonyl CoA provides the carbon skeleton for lipogenesis and also inhibits fat ox

62 central role in generating ATP and providing carbon skeletons for a range of biosynthetic processes i

63 rogen metabolism and a key role in providing carbon skeletons for amino acid biosynthesis.

64 he night as a precursor for the provision of carbon skeletons for amino acid synthesis during the day

65 ymes were increased for providing energy and carbon skeletons for cellular metabolism.

66 Photosynthetically derived sugar provides carbon skeletons for lipid biosynthesis.

67 oin isoprenoid units for construction of the carbon skeletons for over 55,000 naturally occurring iso

68 hat simple alkanes with more highly branched carbon skeletons, for example, isobutane and neopentane,

69 eaction to rapidly construct the tetracyclic carbon skeleton from (R)-carvone and the late-stage appl

70 and efficient entry to a variety of bicyclic carbon skeletons from simple precursors.

71 rboxylic acid (TCA) cycle flux and efflux of carbon skeletons from the cycle (cataplerosis) were both

72 n situ in the transition zone and gain their carbon-skeletons from Suc and triglycerides.

73 nzymes involved in construction of the basic carbon skeleton, have been identified in insects to date

74 roperties, combined with their unprecedented carbon skeletons, have drawn wide attention to phytochem

75 Preservation of the 13C-13C-12C carbon skeleton in labeled alanine and alanine-containin

76 e and find, surprisingly, that extending the carbon skeleton in propynal analogs slows down decoheren

77 cNAc provides an entry into branching of the carbon skeleton in this compound.

78 t for the synthesis of more complex aromatic carbon skeletons in deep space.

79 ilding blocks for construction of isoprenoid carbon skeletons in nature.

80 range of cyclic monoterpenes bearing diverse carbon skeletons, including members of the p-menthane (1

81 Its carbon skeleton is constructed from ferulic acid, veratr

82 the position of the nitrogen atom within the carbon skeleton is crucial for reducing strain energy an

83 apple are biphenyls and dibenzofurans, whose carbon skeleton is formed by biphenyl synthase (BIS), a

84 e decades ago, how their nitrogen-containing carbon skeleton is synthesized by microbial producers re

85 tic pathway for the neomangicol and mangicol carbon skeletons is proposed on the basis of the incorpo

86 rpenoid featuring an unprecedented 5-5-6-6-3 carbon skeleton, is reported.

87 lass of adenosylcobalamin (AdoCbl)-dependent carbon skeleton isomerases and catalyzes the rearrangeme

88 by decarboxylation and re-arrangement of the carbon skeleton, leading to ring contraction and branch

89 on their outer shell C atoms, rendering the carbon skeletons less susceptible to corrosion by oxygen

90 utamine, glucose via glycolysis provides the carbon skeletons, NADPH, and ATP to build new cancer cel

91 A (1) and B (2), having a novel tetracyclic carbon skeleton named cumbiane, have been isolated.

92 regions that allowed identification of their carbon skeleton number, number of double bonds, and doub

93 The high natural abundance and novel carbon skeleton of 1 suggests a rare terpene cyclase mac

94 hat the unpaired electron was located on the carbon skeleton of 4,5-trans-4,5-dehydrolysine.

95 atropodiastereoselectivity), completing the carbon skeleton of 5.

96 gy could be used for the construction of the carbon skeleton of a wide variety of alkyl or arylterpen

97 The carbon skeleton of any organic molecule serves as the fo

98 ic acid and a successful construction of the carbon skeleton of axinellamine.

99 Biosynthesis of the polyketide-derived carbon skeleton of daunorubicin (DNR) begins with propio

100 The synthesis of the carbon skeleton of filipin III, a polyenic macrolactone

101 The tetracyclic carbon skeleton of hainanolidol and harringtonolide was

102 However, attempts to complete the carbon skeleton of hirsutellone B via transannular carbo

103 ence was developed to construct the complete carbon skeleton of HMP-Y1 and atrop-HMP-Y1 via a symmetr

104 iodide 23 led to diene 42, with the complete carbon skeleton of leptofuranin D.

105 formation-fragmentation gave the macrocyclic carbon skeleton of obtusallene VII with a bromine atom a

106 One group involves scission of the 6-carbon skeleton of SQ into two fragments with metabolic

107 tracycle 5 (57% overall), which contains the carbon skeleton of the aglycon of 3.

108 ive site and then principally rebinds to the carbon skeleton of the cinnamate intermediate to complet

109 ic synthesis of a dimer bearing the complete carbon skeleton of the dimeric pyranonaphthoquinone natu

110 The tetracyclic carbon skeleton of the elisapterosins is undescribed and

111 cific extension cycle in the assembly of the carbon skeleton of the FK506 macrolactone ring.

112 e boron-aldol reaction to afford the acyclic carbon skeleton of the methylenecylopentane moiety; (ii)

113 ective iodolactonization that form the basic carbon skeleton of the modified ribose.

114 the main coupling processes to assemble the carbon skeleton of the molecule.

115 e 4 and aldehyde 5 to establish the complete carbon skeleton of the natural product in the form of al

116 ow that the radical is centered on C1 of the carbon skeleton of the substrate in agreement with an ea

117 oupling between the radical, centered on the carbon skeleton of the substrate, and the low-spin Co(2+

118 sulfite and enable utilization of the entire carbon skeleton of the sugar to support the growth of th

119 functionality that is used to establish the carbon skeleton of the target; type 2, which is used to

120 This approach installed much of the complex carbon skeleton of tubingensin A in one step from fragme

121 to quantify key substructures assembling the carbon skeletons of DOM from four main Amazon rivers and

122 cific demands for energy, reducing power and carbon skeletons of expanding cells.

123 n include late-stage nitrogen insertion into carbon skeletons of natural products with previously una

124 The carbon skeletons of over 55,000 naturally occurring isop

125 leading to incorporation of oxygen into the carbon skeletons of PAHs.

126 ly complete chemical space for the potential carbon skeletons of products from monoterpenoid synthase

127 Terpenoid synthases construct the carbon skeletons of tens of thousands of natural product

128 The carbon skeletons of terpenoids are generated through car

129 In all eukaryotes, the carbon skeletons of these compounds are generated by oxi

130 ment of terpene synthases that construct the carbon skeletons of these compounds.

131 The carbon skeletons of these two groups of taxanes differ s

132 ectroscopic analyses and represent two novel carbon skeletons, one with an unusual proposed biosynthe

133 to constrain aromaticity accounting for the carbon skeleton only.

134 atterns: complete preservation of the intact carbon skeleton or extensive degradation and resynthesis

135 es in multicellular organisms: as sources of carbon skeletons, osmolytes, signals, and transient ener

136 imonene oxidation favors the scission of the carbon skeleton, producing more volatile products.

137 With the carbon skeleton provided by 2-oxoglutarate, ammonia/ammo

138 These natural products represent four novel carbon skeletons, providing the first examples of diterp

139 nclude scarless C-C bond cleavage as well as carbon skeleton rearrangement (NIH shift) occurring on a

140 (AdoCbl)-dependent enzyme that catalyzes the carbon skeleton rearrangement of isobutyryl-CoA to butyr

141 endent glutamate mutase catalyzes an unusual carbon skeleton rearrangement that proceeds through the

142 cterized B12-dependent mutases that catalyze carbon skeleton rearrangement, for which methylmalonyl-c

143 to the migrating carbon in facilitating the carbon skeleton rearrangement.

144 ncluding substrate activation, CoA ligation, carbon-skeleton rearrangement and decarboxylation.

145 es are radical enzymes catalyzing reversible carbon skeleton rearrangements in carboxylic acids.

146 ent radical enzymes that perform challenging carbon skeleton rearrangements in primary and secondary

147 nosylcobalamin-dependent isomerases catalyze carbon skeleton rearrangements using radical chemistry.

148 lamin (AdoCbl)-dependent isomerases catalyze carbon skeleton rearrangements using radical chemistry.

149 ole-derivatives involved in enzyme-catalyzed carbon skeleton rearrangements, methyl-group transfers,

150 ghly similar radical enzymes, which catalyze carbon skeleton rearrangements, methylmalonyl-CoA mutase

151 ontrast to the enzymes catalyzing reversible carbon skeleton rearrangements, the dimethylbenzimidazol

152 , including reduction of ribonucleotides and carbon skeleton rearrangements.

153 uting one of the shortest routes to the full carbon skeleton reported to date.

154 eet10a,b embryos reduced the availability of carbon skeletons required for oil synthesis and was asso

155 ernative sources of amino acids, energy, and carbon skeletons, respectively.

156 succinic anhydride and one had a rearranged carbon skeleton resulting from ring-contraction to give

157 The naked carbon skeleton strategy is based on the production of a

158 otosynthesis and is essential for energy and carbon skeleton supply of the entire organism.

159 wn plants had a higher demand for energy and carbon skeletons than ambient CO(2)-grown plants in ligh

160 new family of natural products with a unique carbon skeleton that cause endoplasmic reticulum stress.

161 Streptomyces maritimus" has an unprecedented carbon skeleton that is derived from an aromatic polyket

162 reducing power, in the form of NADH, and one-carbon skeletons that are oxidized to carbon dioxide for

163 Metabolites 1 and 2 contain unusual carbon skeletons that are previously undescribed and the

164 capture numerous compounds including two new carbon skeletons that were characterized using NMR and c

165 f a molecule based on the isoneoamphilectane carbon skeleton, the absolute configuration of compound

166 lated another series of compounds with a new carbon skeleton, the sequoiamonascins.

167 e first izidine having a branch point in its carbon skeleton to be identified from ants, and detectio

168 uorination, followed by rearrangement of the carbon skeleton to generate a key tertiary carbocation i

169 whether this veinal photosynthesis supplies carbon skeletons to particular metabolic pathways.

170 [1,6-13C2]glucose, a novel tracer of glucose carbon skeleton turnover, and [U-13C]propionate, a trace

171 Glucose carbon skeleton turnover, as reported by the dilution of

172 The chain lengths of isoprenoid carbon skeletons vary widely from neryl pyrophosphate (C

173 s is controlled by the relative abundance of carbon skeletons versus amino acids.

174 An alternative route to this carbon skeleton was also achieved that provides the lact

175 The unique double bridged carbon skeleton was assembled by synthesis of the bicycl

176 complexes and numerous compounds with novel carbon skeletons were obtained.

177 The requisite five-carbon skeletons were prepared using 4 + 1, 3 + 2, 2 + 2

178 substitution numbers, functional groups, and carbon skeletons were three important factors controllin

179 the tetrameric COTCNR3 possesses a flexible carbon skeleton which undergoes conformational changes u

180 chain elongation have head-to-tail (regular) carbon skeletons, while those from cyclopropanation, bra

181 ows rapid, stereocontrolled formation of the carbon skeleton with a desirable protecting group scheme

182 ar unidentified class of tricyclic diterpene carbon skeletons with an unusual tricyclic spiro-hydrind

183 e the potential to afford complex polycyclic carbon skeletons with impressive efficiency, which are o