ライフサイエンスコーパス: carbon-13

1 f heavy, natural abundance isotopes, such as carbon-13.

2 Hyperpolarized (HP) carbon 13 ((13)C) MRI is an emerging molecular imaging m

3 oma (GBM) metabolism by using hyperpolarized carbon 13 ((13)C) MRI to monitor the exchange of the hyp

4 tal muscle after the onset of exercise using carbon 13 ((13)C) MRI with hyperpolarized (HP) [1-(13)C]

5 ect on lactate flux with hyperpolarized (HP) carbon 13 ((13)C) MRI.

6 In this study, we used hyperpolarized carbon 13 ((13)C)-labeled pyruvate magnetic resonance sp

7 emission tomography (PET) and hyperpolarized carbon 13 ((13)C)-pyruvate magnetic resonance (MR) spect

8 ptor agonist, Acipimox, using hyperpolarized Carbon-13 ((13) C) magnetic resonance spectroscopy.

9 ies measured at 1 s include methane, ethane, carbon-13 ((13)C) and deuterium (D) isotopes of methane,

10 ation of the non-radioactive stable isotopes carbon-13 ((13)C) and nitrogen-15 ((15)N) into polar met

11 young and old men by using uniformly labeled carbon-13 ((13)C) fatty acids.Six young ( approximately

12 As hyperpolarized (HP) carbon-13 ((13)C) metabolic imaging is clinically transl

13 Using hyperpolarized carbon-13 ((13)C)-magnetic resonance spectroscopy, in vi

14 Hyperpolarized (HP) carbon-13 [(13)C] enables the specific investigation of

15 3)C MRI after injection of hyperpolarized [1-carbon 13 {(13)C}]-pyruvate and DCE MRI at 3 T at baseli

16 feasibility of the use of hyperpolarized [1-carbon 13 {(13)C}]-pyruvate for real-time measurement of

17 onate production from hyperpolarized (HP) [1-carbon 13 {(13)C}]-pyruvate in skeletal muscle rapidly r

18 Carbon-13 (13C) solid-state nuclear magnetic resonance (

19 8.1 containing a bicyclo[1.1.0]butyl ring on carbons 13-16, and the minor product as 9R,10R-epoxy-11t

20 ically useful isotopes, including carbon-14, carbon-13 and deuterium.

21 s are labeled by modulating their content of carbon-13 and labeled fragments identified from the dist

22 ched by about 20% in the NMR-active isotopes carbon-13 and nitrogen-15.

23 six brazzein proteins labeled uniformly with carbon-13 and nitrogen-15.

24 r glucose concentrations were measured using carbon-13 and phosphorous-31 nuclear magnetic resonance

25 e-6-phosphate concentration were measured by carbon-13 and phosphorus-31 nuclear magnetic resonance s

26 vel nuclear magnetic resonance approach with carbon-13 and phosphorus-31 to measure intramuscular glu

27 actors, circular dichroism measurements, and carbon-13 and proton chemical shift index values.

28 ith either natural isotopes or enriched with carbon-13, and mass spectrometry analysis.

29 zed reactions of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) at pD 7.

30 the reaction of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) catalyze

31 arcinomas to study uptake of glucose derived carbon ((13)C) and glutamine derived nitrogen ((15)N) by

32 Carbon ((13)C) and oxygen ((18)O) isotopes in carbonates

33 Stable carbon ((13)C) and radiocarbon ((14)C) isotopic data dem

34 todissociation and sputtering enriches heavy carbon ((13)C) in the Martian atmosphere, partially comp

35 We measured carbon ((13)C/(12)C) and nitrogen ((15)N/(14)N) isotope

36 (NMR) tool for determining position-specific carbon ((13)C/(12)C) isotope ratios within complex organ

37 Isotopes of heavier gases including carbon ((13)C/(14)C), nitrogen ((13)N), and oxygen ((18)

38 The shallow-water organic-carbon (13)C content has a 29 per thousand range in valu

39 imentally supported by measurements of alpha-carbon (13)C-NMR chemical shifts for eGFP mRNA LNPs of b

40 Carbon (13)C/(12)C isotope amount ratios have been measu

41 Organic carbon (13)C/(12)C isotope ratios are commonly obtained

42 position onto minerals, characterizing total carbon, (13)C enrichment, and SOM chemistry over three g

43 lated hearts were perfused with either the 4 carbon, (13)C-labeled ketone (D3-hydroxybutyrate) or the

44 labeled ketone (D3-hydroxybutyrate) or the 4 carbon, (13)C-labeled SCFA butyrate in the presence of g

45 Because carbonyl carbons ((13)C') suffer from serious relaxation enhancem

46 3)C NMR shieldings of all the imidazole ring carbons ((13)C(gamma), , and ) for each of the two tauto

47 orts using the AA isotopologue deuterated at carbon 13 (C13).

48 PO2-, (CD3CH2O)2PO2- and (CD3CD2O)2PO2-] and carbon-13 [(CH3 13CH2O)2PO2-] derivatives in the stable

49 Carbon-13 chemical shift anisotropy (CSA) tensors for va

50 contemporary carbon-14 samples with varying carbon-13 concentrations were used to assess the method

51 ophy also explain an enigmatic offset in the carbon-13 content of microbial methane from coals and co

52 be distinguishable from fragments of natural carbon-13-content proteins.

53 The higher value of carbon-13 delta(iso) in alkylidene complexes relative to

54 we show how to overcome this hurdle by using carbon-13-detected NMR.

55 Carbon-13 discrimination (Delta), corrected for backgrou

56 data obtained from laboratory experiments on carbon-13 discrimination by vascular land plants and mar

57 uits and leaves but also large quantities of carbon-13-enriched foods such as grasses and sedges or a

58 onstrated for identification of fragments of carbon-13-enriched glutathione transferase within a comp

59 We show that carbon-13 enrichment to just 2.3% of total carbon (about

60 o[2.2.2]diazaoctane structural unit) through carbon-13 feeding studies, support the existence of a co

61 nuclear magnetic resonance spectroscopy, and carbon-13 feeding studies.

62 elayed fluorescence of isotopically enriched carbon-13 fullerene C(70) ((13)C(70)).

63 mum(2) spatial resolution and hyperpolarized carbon-13 images with 250 x 250 mum(2) in-plane spatial

64 We measured carbon 13 incorporation into brain glutamate and glutami

65 eta-oxidation to carbon dioxide labeled with carbon-13 increased from 0.085% of dose/h at baseline to

66 o-IRMS) was used to simultaneously determine carbon 13 isotope ratio (delta(13)C) of organic acids, g

67 Carbon-13 isotope effects have been determined for all f

68 logy, as it does not recur to nitrogen-15 or carbon-13 isotope enrichment.

69 The efficient incorporation of two carbon-13 isotopes into phenethylamines was accomplished

70 use the natural variations in 13C:12C ratio (carbon-13 isotopic abundance [delta13C]) of n-3 PUFA sup

71 entification is facilitated by resolution of carbon-13 isotopic distributions.

72 Carbon-13 isotopic labeling studies show that both carbo

73 labeled version generated the corresponding carbon-13 labeled benzophenones.

74 complex ([(N(2)N)Ni-Cl]) in combination with carbon-13 labeled CO, alkyl iodide, sodium methoxide, ph

75 ursor, in the CO-producing chamber, with its carbon-13 labeled version generated the corresponding ca

76 ed in an older population by using uniformly carbon-13-labeled DHA ((13)C-DHA).

77 Experimentally, 2,3-carbon-13-labeled diacetyl has a disconnected eigenstate

78 The uniformly carbon-13-labeled EPA concentration was 2.6 times as hig

79 Carbon-13-labeled graphite can be used to prepare chemic

80 In amorphous carbon-13-labeled PET, the statistics of the O-13CH2-13C

81 Carbon-13--labeled glucose and glycogen were detected in

82 or 24 hr in LPD solution with the following carbon-13--labeled substrates: 5 mM glucose (Perfadex gr

83 h product stereoselectivity is quantified by carbon-13 labeling and shown to depend on external force

84 results from deuterium exchange experiments, carbon-13 labeling experiments, (1)H NMR monitoring stud

85 Carbon-13 labeling of the aromatic ring positions of tyr

86 ally, the method was applied to the specific carbon-13 labeling of the beta-amyloid binding compound,

87 Carbon-13 labeling of the Phe residue of penetratin was

88 Carbon-13 labeling studies showed that the (13)C NMR che

89 eutically active compounds, whereby complete carbon-13 labeling was successfully accomplished.

90 experiments, and other methods that rely on carbon-13 labeling.

91 A fully carbon-13-labelled internal standard was used to compens

92 ith endoscopy at 1, 3, and 6 months and with carbon-13-labelled urea breath test at 3 months.

93 H. pylori status was assessed by the carbon-13-labelled urea breath test.

94 emonstrates the power of combining selective carbon-13 labelling with NMR spectroscopy as a sensitive

95 Hyperpolarized carbon-13 magnetic resonance imaging is a promising tech

96 probe of real-time metabolism in vivo, using carbon-13 magnetic resonance imaging.

97 Hyperpolarized carbon-13 magnetic resonance is a new metabolic imaging

98 arized fumarate is a promising biosensor for carbon-13 magnetic resonance metabolic imaging.

99 re removed and frozen in liquid nitrogen for carbon-13 magnetic resonance spectroscopic (MRS) analysi

100 Positron emission tomography and carbon-13 magnetic resonance spectroscopic imaging (MRSI

101 Carbon-13 magnetic resonance spectroscopy at ultra-high-

102 pectively, P = .84).ConclusionHyperpolarized carbon 13 measurements of pyruvate metabolism can provid

103 Carbon-13 metabolite tracing indicated heightened glutat

104 Nitrogen-15 backbone and carbon-13 methyl NMR relaxation was measured to investig

105 Hyperpolarized carbon 13 MRI ((13)C MRI) is a novel imaging approach th

106 including deuterium imaging, hyperpolarized carbon 13 MRI and MRS, chemical exchange saturation tran

107 clinical methods (fluorodeoxyglucose PET and carbon 13 MRI and spectroscopy) do not allow quantitativ

108 Keywords: Hyperpolarized Carbon 13 MRI, Molecular Imaging, Cancer, Tissue Metabol

109 Hyperpolarized carbon-13 MRI allows response assessment in patients wit

110 ular imaging using hyperpolarized proton and carbon-13 MRI contrast media and low-field (47.5 mT) pre

111 core 1 chains, a value in agreement with the carbon-13 NMR analysis of the native mucin.

112 Carbon-13 NMR analysis shows that all four compounds are

113 e in CDCl3 to afford high-quality proton and carbon-13 NMR data.

114 Carbon-13 NMR line shape changes are attributed to inver

115 Carbon-13 NMR line shape changes indicate that the syste

116 Carbon-13 NMR shows that all of the above compounds are

117 erate valence tautomers, was investigated by carbon-13 NMR spectroscopy at a range of temperatures in

118 irmed by [(11/13)C]colabeling and subsequent carbon-13 NMR spectroscopy.

119 Alternatively, carbon-13 nuclear magnetic resonance ((13)C NMR) is a fa

120 transform infrared spectroscopy (FT-IR) and carbon-13 nuclear magnetic resonance ((13)C NMR).

121 traditional theory, an interpretation of new carbon-13 nuclear magnetic resonance measurements of the

122 We have obtained the carbon-13 nuclear magnetic resonance spectra of a series

123 platform based on individually controllable carbon-13 nuclear spins in diamond.

124 nascent parahydrogen-derived protons to the carbon-13 nucleus via magnetic field cycling yielding C-

125 ar spin polarization (%PH ) of ca. 3.3 % and carbon-13 polarization (%P13C ) of ca. 1.8 % were achiev

126 lated to the presence of a side chain at the carbon 13-position, to the addition of a xylosyl group a

127 d over a range of 30 percent for the various carbon-13 positions.

128 olenic acid (C18:3) and regioselectivity for carbon 13, producing 13-Hydroperoxyoctadeca-9,11,15-trie

129 We employed a carbon-13 pulse-chase experiment to investigate how a te

130 The feasibility of Carbon-13 Radiofrequency (RF) Amplification by Stimulate

131 In this article, we show that carbon-13 RASERs can be controlled by changes to the mag

132 Combining carbon-14 with carbon-13 reveals the impact of African savanna burning,

133 n was labeled uniformly with nitrogen-15 and carbon-13 so that its conformation could be determined i

134 neighboring spins in both phosphorus-31 and carbon-13 spectra.

135 Carbon-13 spectroscopy promises to be a useful method fo

136 selectively initialize, control and read out carbon-13 spins in the surrounding spin bath and constru

137 d to multiple isotopes, including deuterium, carbon-13, sulfur-34, and radioactive carbon-14.

138 istic of archaea are so strongly depleted in carbon-13 that methane must be the carbon source, rather

139 droxyacetone (DHA) to deliver hyperpolarized carbon-13 to the perfused mouse liver.

140 Amplex glucose assay, fluorescence and carbon-13 tracing studies demonstrate that FAK promotes

141 aining molecules, including those containing carbon-13 using platinum and boron-doped diamond (BDD) e