ライフサイエンスコーパス: carbonylation

1 eactions (Sonogashira, Suzuki, and reductive carbonylation).

2 o a Bronsted acid site in the 8MR to undergo carbonylation.

3 spersed ReO(4) on inert supports for alcohol carbonylation.

4 cies present in the MOR side pockets undergo carbonylation.

5 th annelation, while the reverse is true for carbonylation.

6 tissue lipid aldehyde production and protein carbonylation.

7 philicity increases upon both annelation and carbonylation.

8 be more influential on the extent of protein carbonylation.

9 omplex attenuated ouabain-stimulated protein carbonylation.

10 eptibility to mitochondrial membrane protein carbonylation.

11 col involves Michael addition and subsequent carbonylation.

12 se secondary structure, oligomerization, and carbonylation.

13 ein amino acids in a reaction termed protein carbonylation.

14 implications for catalytic reactions beyond carbonylation.

15 metathesis followed by trans-hydrostannation/carbonylation.

16 examined and applied in palladium-catalyzed carbonylation.

17 resent alternative reactants to enable (11)C-carbonylation.

18 uction yields (100 t/y) compared to methanol carbonylation (0.26 pound/kg, 261 pound/t) and ethane di

19 ts activation), malonyl-CoA content, protein carbonylation (a marker of oxidative stress), plasma adi

20 e protocol was set up using Paraquat-induced carbonylation, a model that induces protein aggregation

21 Protein carbonylation, a sensitive marker of hemoglobin neurotox

22 proceeds via carbonylation-carbocyclization-carbonylation-alkynylation involving sequential insertio

23 days, and protein oxidation was evaluated as carbonylation (alpha-amino adipic and gamma-glutamic sem

24 oxidation, total carbonylation, and specific carbonylation (alpha-amino adipic and gamma-glutamic sem

25 d cysteine residues, referred to as "protein carbonylation." Although not widely appreciated, reactiv

26 ines via a sequential one-pot multicomponent carbonylation/amination reaction has been developed.

27 Levels of protein carbonylation, amount of glutathione stores, and lipid p

28 t synthesize CL, exhibited increased protein carbonylation, an indicator of reactive oxygen species (

29 uropathies, we predicted that an increase in carbonylation and aggregation of PMP22 may be associated

30 rkers of proteostasis stress such as protein carbonylation and aggregation.

31 s exhibited significant elevation in protein carbonylation and alterations in protein conformation.

32 tes, complex I protein and activity, protein carbonylation and ATP levels were all fully protected in

33 ied catalytic system for tandem Pd-catalyzed carbonylation and C-C cross-coupling via C-H activation

34 We confirmed the carbonylation and degradation of MyBPC using HL-1 cardio

35 The carbonylation and degradation of MyBPC were time- and dr

36 We confirmed carbonylation and degradation of this protein under oxid

37 m to industrial chemical processes: methanol carbonylation and ethane direct oxidation.

38 n the generation of reactive oxygen species, carbonylation and glutathionylation of cellular proteins

39 plants, as evidenced from decreased protein carbonylation and hydrogen peroxide accumulation.

40 The use of compatible epoxide carbonylation and lactone polymerization catalysts allow

41 sed with OA treatment as measured by protein carbonylation and lipid peroxidation.

42 ptophan and thiols depletion, higher protein carbonylation and more intense formation of protein cros

43 n p38K are associated with increased protein carbonylation and Nrf2-dependent transcription, while ad

44 l ether moiety to direct gamma- or delta-C-H carbonylation and olefination of alcohols.

45 tions, and (iv) one-flask palladium-mediated carbonylation and ring closure to form the imide.

46 es (UF) for the extent of protein oxidation (carbonylation and Schiff base formation) and their senso

47 ical examples, such as alcohol oxidation and carbonylation and the asymmetric reduction of ketones.

48 s contaminated with chlorpyrifos to evaluate carbonylation and the effect of simulated gastrointestin

49 lucose) for their ability to promote protein carbonylation and tryptophan depletion in myofibrillar p

50 and exhibit decreased mitochondrial protein carbonylation and UCP2-dependent reduction in intracellu

51 ding lysine, arginine, proline and threonine carbonylation, and cysteine oxidation.

52 ocyclization, ring cleavage, hydrogen shift, carbonylation, and decarbonylation contributed to CBZ tr

53 higher levels of lipid peroxidation, protein carbonylation, and DNA oxidative damage even at a young

54 ctive aldehyde 4-hydroxynonenal (HNE) caused carbonylation, and HNE-glutathione adducts were detected

55 gnals related to lipid peroxidation, protein carbonylation, and nitration in WAT and liver.

56 range of products through (hetero)arylation, carbonylation, and olefination reactions.

57 dinitrogen loss became competitive with N(2) carbonylation, and significant quantities of the zircono

58 tion was evaluated as thiol oxidation, total carbonylation, and specific carbonylation (alpha-amino a

59 f these results, we propose that autoinduced carbonylation, and thus removal of a positive charge in

60 -induced oxidative damage to DNA and protein carbonylation are involved in the observed toxicity of H

61 This process and further carbonylation are slow compared to isomerizing methoxyca

62 These data identify carbonylation as a novel mechanism that contributes to S

63 In the biotechnology industry, oxidative carbonylation as a post-translational modification of pr

64 We focused on protein carbonylation as an indicator of severe oxidative damage

65 This was achieved by bis-carbonylation at C-3 of the magnesium salt of 6-bromoind

66 on of lipid peroxidation, which led to STING carbonylation at C88 and inhibited its trafficking from

67 Carbonylation at the alpha-position with respect to the

68 tic studies indicate a radical atom transfer carbonylation (ATC) mechanism to form acyl halide interm

69 rphyrins, and lipid peroxidation and protein carbonylation blockers/inhibitors (edaravone and lazaroi

70 of vemurafenib and UVA caused little protein carbonylation but were nevertheless inhibitory to nucleo

71 e SPI did not increase substantially protein carbonylation, but increased surface-exposed hydrophobic

72 2) C-H activation (i.e., ortho acylation) or carbonylation by activation of the carbonyl group (i.e.,

73 Deleterious effects of protein carbonylation by reactive oxygen species (ROS) make unde

74 The insertion cascade proceeds via carbonylation-carbocyclization-carbonylation-alkynylatio

75 rsed the effects of IPC on postischemic Rpt5 carbonylation, cardiac function, morphology and morphome

76 step by PdI(2)/KI-catalyzed direct oxidative carbonylation, carried out in alcoholic media under rela

77 ted by effective activation to a homogeneous carbonylation catalyst [(dtbpx)PdH(L)](+) by addition of

78 rs also demonstrated the practicality of the carbonylation catalyst for complex molecule synthesis as

79 Furthermore, carbonylation, CoA binding, and methyl transfer can all

80 owed to react under PdI2-catalyzed oxidative carbonylation conditions, depending on the nature of the

81 Carbonylation converts [H1H](0) into [1(CO)](0).

82 s of 8-oxo-dG-modified DNA and total protein carbonylation corresponded to cardioprotective activity.

83 ted 2-aminoquinazolin-4(1H)-ones by a domino carbonylation/cyclization process.

84 A Pd-catalyzed and ligand-free carbonylation/cycloaddition/decarboxylation cascade synt

85 er forms contained higher degrees of damage (carbonylation, deamidation) and far less IE.

86 allmarks of oxidative stress such as protein carbonylation, decreased aconitase activity, and lower l

87 ns that are susceptible to substoichiometric carbonylation during oxidative stress.

88 alkylation, halogenation, carboxylation, and carbonylation), each representing a distinct handle for

89 duct release, as evidenced by direct carbide carbonylation experiments.

90 ibited severe lipid peroxidation and protein carbonylation, for oxidative stress damage at the cellul

91 Both annelation and carbonylation have been found to decrease the stability

92 Increased (P<0.05) carbonylation in a 53-kDa band following I/R was diminis

93 pression of GSTA4 and the role(s) of protein carbonylation in adipocyte function.

94 th increased DJ-1 oxidative modification and carbonylation in FECDi as compared with HCECi.

95 was employed to identify specific targets of carbonylation in GSTA4-silenced or overexpressing 3T3-L1

96 dot blot method for quantitation of protein carbonylation in homogenates or purified proteins.

97 f sensitivity allowed measurement of protein carbonylation in individual Drosophila.

98 novel DNPH-based method to quantify protein carbonylation in muscle and meat.

99 cies formation and a higher level of protein carbonylation in response to RSV infection.

100 istinct advantage over traditional reductive carbonylation in that no carbon monoxide, pressurized ga

101 To address the role of protein carbonylation in the pathogenesis of mitochondrial dysfu

102 Ethanol sensitivity and increased protein carbonylation in the taz1Delta mutant but not in crd1Del

103 be utilized for the detection of biomolecule carbonylation in various cancer cell lines.

104 show significantly lower protein oxidation (carbonylation) in Mexican free-tailed bats (Tadarida bra

105 Cu-MOR and Cu-ZSM-5 are oxidation active but carbonylation inactive.

106 red adipocytes resulted in increased protein carbonylation, increased mitochondrial ROS, dysfunctiona

107 superoxide presence, and detectable protein carbonylation. Inhibition of Complexes I and IV of the e

108 earlier reported transition-metal-catalyzed carbonylations involved either toxic carbon monoxide (CO

109 These results suggest that protein carbonylation is a post-translational modification invol

110 Elevated protein carbonylation is accompanied by diminished complex I act

111 e development in the field of photocatalytic carbonylation is described by compiling the literature o

112 from aryl chlorides via palladium-catalyzed carbonylation is described using atmospheric pressure of

113 The effect of carbonylation is more pronounced than annelation toward

114 However, the effect of carbonylation is more pronounced than annelation toward

115 Ouabain-stimulated protein carbonylation is reversed after removal of ouabain, and

116 Carbonylation is the covalent, non-reversible modificati

117 Protein carbonylation is the most commonly used measure of oxida

118 probes that can be utilized in site-specific carbonylation labeling to enhance new diagnostic approac

119 s a target for oxidant-induced PTMs, such as carbonylation, leading to impaired function during epile

120 ich significantly correlated with fibrinogen carbonylation level (r(2)=0.33, P<0.0001), residual beta

121 new procedure reflected an increased protein carbonylation level measuring overall two to fourfold mo

122 Our results showed that carbonylation level that differs in response to exogenou

123 ring striatal aconitase activity and protein carbonylation levels.

124 chanisms by which alpha-dicarbonyls-mediated carbonylation likely influenced the impairment of such p

125 on step corresponds to subsequent side chain carbonylation, likely at Lys72/73.

126 further broadens the application of this new carbonylation method.

127 ylis-Hillman reactions, conjugate additions, carbonylations, methylations, silylations, and brominati

128 Taken together, the data indicate that carbonylation modification of the Na/K-ATPase alpha1 sub

129 ular enolate alkylation, an effective Stille carbonylation/Nazarov cyclization sequence, and a high-r

130 We report the regioselective carbonylation of 2,2-disubstituted epoxides to beta,beta

131 Palladium-catalyzed carbonylation of 2,4-enyne carbonates in an alcohol and

132 The palladium-catalyzed carbonylation of 2-(propynylthio)benzimidazoles bearing

133 were selectively obtained when the oxidative carbonylation of 2-alkynylbenzamides, bearing a terminal

134 Thus, oxidative carbonylation of 2-ethynylbenzamides, bearing a terminal

135 licon-tethered acrylate; an efficient Stille carbonylation of a sterically encumbered vinyl triflate;

136 Monoselective gamma-C-H olefination and carbonylation of aliphatic acids has been accomplished b

137 nent reaction based on a palladium-catalyzed carbonylation of alpha-chloroketones in the presence of

138 yzed protocol for the oxidative cross double carbonylation of amines and alcohols.

139 On the other hand, the oxidative carbonylation of amines occurs with alpha-bromomethyl su

140 They promote the catalytic carbonylation of amines under relatively mild conditions

141 Palladium-catalyzed chemoselective carbonylation of aminophenols with iodoarenes was realiz

142 ed that 4-HNE treatment of cells resulted in carbonylation of AMPKalpha/beta, which was not observed

143 The cascade process involves carbonylation of an aryl iodide/Michael acceptor to give

144 (-) catalyst for a late-stage regioselective carbonylation of an enantiomerically pure cis-epoxide to

145 activates CO and catalytically promotes the carbonylation of an o-quinone into a cyclic carbonate.

146 in posterior eyecups of mutant mice, whereas carbonylation of an RPE-specific protein was observed in

147 Carbonylation of annexin A1 by endothelin-1 was followed

148 The direct carbonylation of aromatic sp(2) and unactivated sp(3) C-

149 A method for the Pd-catalyzed carbonylation of aryl bromides has been developed using

150 In detail, the carbonylation of aryl dibromides with indoles and C-H ac

151 In addition, a flow Pd-catalyzed carbonylation of aryl halides is successfully reported.

152 conducting the palladium-catalyzed reductive carbonylation of aryl iodides and bromides using 9-methy

153 ation has been found to facilitate the rapid carbonylation of aryl iodides into acid chlorides via re

154 omplished using a palladium-catalyzed double carbonylation of aryl iodides with near stoichiometric c

155 loride synthesis via the palladium-catalyzed carbonylation of aryl iodides.

156 general protocol for the palladium-catalyzed carbonylation of aryl tosylates and mesylates to form es

157 tially useful alternative to metal-catalyzed carbonylation of aryl triflates.

158 Pd(0)-mediated (11)C-carbonylation of aryl(mesityl)iodonium salts followed by

159 herein two catalysts for the regioselective carbonylation of cis-disubstituted epoxides.

160 t of oxidative modification, we assessed the carbonylation of cytosolic proteins in phagocytic neutro

161 Unprecedented insight into the carbonylation of dimethyl ether over Mordenite is provid

162 Altogether, carbonylation of disubstituted epoxides is established a

163 The carbonylation of each particular protein was quantified

164 bstrate scope has been demonstrated allowing carbonylation of electron-rich, electron-poor, and heter

165 e derived from beta-lactones prepared by the carbonylation of epoxides.

166 e stress markers (P<0.001) and with a marked carbonylation of fibrinogen (P<0.001), whose secondary s

167 owever, an effective catalyst for the direct carbonylation of methane to acetic acid, which might ena

168 vehicle for the low-temperature vapor-phase carbonylation of methanol by insertion of CO into the O-

169 ive site in supported gold catalysts for the carbonylation of methanol has been identified as dimers/

170 port (SiO(2)) for the halide-free, gas phase carbonylation of methanol to AA.

171 istic study of the electrochemical oxidative carbonylation of methanol with CO for the synthesis of d

172 rocesses, such as the Cativa process for the carbonylation of methanol.

173 Several examples on Pd-catalysed carbonylation of methyl C(sp(3))-H bonds with gaseous CO

174 Carbonylation of MyBPC showed significant functional imp

175 myosin light chain-2 slow and troponin T and carbonylation of myosin heavy chains.

176 and PP2, which correlated with a decline in carbonylation of PP2.

177 Catechin (200ppm) reduced significantly carbonylation of protein spots identified as glycogen ph

178 d evoked Ca(2+) release from the SR, reduced carbonylation of RyR2s, and increased binding of [(3)H]r

179 GSTA4-silenced adipocytes displayed elevated carbonylation of several key mitochondrial proteins incl

180 Hip to be square: Direct carbonylation of solutions of the heptaphosphide trianio

181 igand-controlled regioselective Pd-catalyzed carbonylation of styrenes with aminophenols was realized

182 r) catalyzed alkynylations, carbon monoxide (carbonylation of terminal alkynes and alkenes), and othe

183 This work reports oxidative N-dealkylation/carbonylation of tertiary amines to tertiary amides by u

184 Carbonylation of the hafnocene dinitrogen complex, [Me(2

185 HepG2 cells with 4-HNE resulted in increased carbonylation of the lipid phosphatase known as "phospha

186 close proximity to the active site of CI and carbonylation of the residue is predicted to induce subs

187 ysis of target proteins revealed significant carbonylation of the S100A9 subunit of calprotectin, a t

188 N-C bond formation was also accomplished by carbonylation of the silylated product, yielding an unpr

189 Two-electron reductive carbonylation of the uranium(VI) nitride [U(Tren(TIPS))(

190 by hydrogenation and C-H bond activation, as carbonylation of the zirconocene and hafnocene dinitroge

191 and selectivity of Rh(III) in the oxidative carbonylation of toluene to toluic acid.

192 atalysts are reported for the regioselective carbonylation of trans-disubstituted epoxides to cis-bet

193 Furthermore, ouabain stimulated direct carbonylation of two amino acid residues in the actuator

194 The palladium-catalyzed carbonylation of urea derivatives with aryl iodides and

195 tive Pd/C-catalyzed oxidative N-dealkylation/carbonylation of various aliphatic as well as cyclic ter

196 substrates and represent the first catalytic carbonylations of alkyl bromides with carbon monoxide.

197 Catalytic carbonylations of organohalides are important C-C bond f

198 Carbonylations of unactivated alkyl halides remain a cha

199 s to identify the site and extent of protein carbonylation on a proteome-wide scale has expanded our

200 methanol synthesis, and subsequent methanol carbonylation on homogeneous catalysts.

201 iples, understanding the impact of oxidative carbonylation on product quality of protein pharmaceutic

202 tates extended characterization of oxidative carbonylation on recombinant monoclonal antibodies and p

203 to investigate the effect of annelation and carbonylation on the electronic and ligand properties of

204 The effect of annulation and carbonylation on the electronic and ligating properties

205 The effect of annelation and carbonylation on the electronic and ligating properties

206 both species, the dose-response for protein carbonylation parallels that for fecundity reduction, ma

207 The first amine carbonylation part is catalyzed by K(3)PO(4).

208 ant activity towards lipid oxidation and the carbonylation pathway at different concentrations under

209 The carbonylation pathway involves the oxidative deamination

210 n, quercetin and gallic acid) on the protein carbonylation pathway occurred during the oxidation of m

211 This reaction contrasts sharply to the carbonylation pathway well known for homogeneously catal

212 single electron transfer to enable a radical carbonylation pathway.

213 These results suggest that protein carbonylation plays a major instigating role in cytokine

214 de, among others, Friedel-Crafts alkylation, carbonylation, polymerization, cyclization, olefin metat

215 The generality of the C-H carbonylation process is aided by the action of xantphos

216 st state, participating as a reactant in the carbonylation process, and accelerating the final reduct

217 through the development of C-H amination and carbonylation processes, leading to the synthesis of azi

218 ish the exogenous and endogenous ROS induced carbonylation profile in human dermal fibroblasts along

219 fonyl azides employing a palladium-catalyzed carbonylation protocol has been developed.

220 An efficient Pd-catalyzed carbonylation protocol is described for the coupling of

221 DME carbonylation rates are proportional to the number of O-

222 This elementary step controls catalytic carbonylation rates of dimethyl ether (DME) to methyl ac

223 s 3, bearing alkyl or aryl substituents, the carbonylation reaction led to a mixture of Boc-protected

224 An oxidative carbonylation reaction that generates acid chloride func

225 This work discloses a continuous flow carbonylation reaction using iron pentacarbonyl as sourc

226 A Pd-catalyzed oxidative ortho-carbonylation reaction using ketone directing groups to

227 Remarkably, the aforementioned carbonylation reaction was found to be thermally reversi

228 The carbonylation reaction, known to occur predominantly in

229 hen D2O is introduced in the feed during the carbonylation reaction.

230 Carbonylation reactions constitute important methodologi

231 mackerel (Scomber scombrus) mince to undergo carbonylation reactions during chilled storage, and the

232 Carbonylation reactions have been widely used in organic

233 In particular, palladium-catalyzed carbonylation reactions have found broad application in

234 sformation proceeds via two tandem catalytic carbonylation reactions mediated by Pd(P(t)Bu3)2 and pro

235 Pd-catalyzed carbonylation reactions of 1d and 2d did not give the co

236 Carbonylation reactions of amines and phenols are carrie

237 derstanding enables the development of other carbonylation reactions of high importance to chemical i

238 Palladium(II)-catalyzed C-H carbonylation reactions of methylene C-H bonds in second

239 Among the known methodologies, carbonylation reactions represent an atom-efficient tool

240 tion complexes as stoichiometric reagents in carbonylation reactions with (11)CO to produce structura

241 -catalyzed oxidative dehydrogenative C-H/X-H carbonylation reactions with CO constitute one of the mo

242 thway well known for homogeneously catalyzed carbonylation reactions, such as the synthesis of acetic

243 Motivated by stereoinvertive epoxide carbonylation reactions, we developed a two-step epoxida

244 ated using Cu-MOR by coupling oxidation with carbonylation reactions.

245 ay for the discovery of metal-free catalyzed carbonylation reactions.

246 cules via various transition-metal-catalyzed carbonylation reactions.

247 ter sense of spontaneity of these photoredox carbonylation reactions.

248 ive CO detection based on palladium-mediated carbonylation reactivity.

249 mulated Na/K-ATPase.c-Src signaling, protein carbonylation, redistribution of Na/K-ATPase and sodium/

250 However, methylene C(sp(3))-H carbonylation remains a great challenge, largely due to

251 Carbonylation results in thioester formation via a reduc

252 re epoxides were demonstrated to undergo the carbonylation/ring-opening process with retention of ste

253 in adipose tissue leads to increased protein carbonylation, ROS production, and mitochondrial dysfunc

254 Hence, reductive carbonylations run with (13)COgen provide a facile acces

255 Overall, our findings indicate that MyBPC carbonylation serves as a critical determinant of cardio

256 cipitation studies indicated that the 53-kDa carbonylation signal was of proteasomal origin.

257 thoxy species from the oxidation site to the carbonylation site.

258 However, comprehensive identification of carbonylation sites has so far remained a very difficult

259 Here we mapped protein carbonylation sites in raw milk and different brands of

260 The number of carbonylation sites increased with the harsher processin

261 roach were demonstrated by identification of carbonylation sites on both unstressed and oxidized anti

262 he first time the identification of specific carbonylation sites on recombinant monoclonal antibodies

263 demonstrated by identification of 14 common carbonylation sites on three highly similar IgG1s.

264 oach, which enabled direct identification of carbonylation sites without any fractionation or affinit

265 Overall, 53 unique carbonylated peptides (37 carbonylation sites, 15 proteins) were identified.

266 ntally benign process, [Pd]-catalyzed direct carbonylation starting from simple and commercially avai

267 tions of sea buckthorn fruits also inhibited carbonylation stimulated by H2O2/Fe.

268 the last few decades, photocatalytic radical carbonylation strategies have received considerable atte

269 These carbonylation strategies involve the incorporation of a

270 We applied a gas-phase carbonylation technique previously tested on short-lived

271 is far more resistant to IR-induced protein carbonylation than is the much more radiosensitive nemat

272 ium Deinococcus radiodurans accumulates less carbonylation than sensitive organisms, making it a key

273 imal-source were more susceptible to protein carbonylation than soy proteins and globular were more s

274 and suffer more DNA damage and more protein carbonylation than the parent.

275 tential functions of protein adducts such as carbonylation that accumulate in stressed cells have bee

276 r at 140 degrees C further increased protein carbonylation to a high extent.

277 Methanol carbonylation to acetic acid (AA) is a large-scale commo

278 also be transformed through direct oxidative carbonylation to acetic acid, which is commercially obta

279 tured CI identified specific metal catalyzed carbonylation to Arg76 within the 75 kDa subunit concomi

280 reaction occurs in tandem through an initial carbonylation to generate an aroyl halide, which undergo

281 ile synthetic intermediates that can undergo carbonylation to yield acyl anion equivalents.

282 alyzed dehydrogenative C-H/X-H (X = C, N, O) carbonylation transformations under oxidative conditions

283 rotein that showed a significant increase in carbonylation under Dox-induced cardiotoxic conditions i

284 Compared to higher olefins, ethylene carbonylation under identical conditions is much faster,

285 g amino amides employing oxidative catalytic carbonylation using W(CO)(6) as the catalyst, I(2) as th

286 Protein carbonylation was 65% higher in hearts of hypoxic rats c

287 Carbonylation was dependent on NADPH oxidase and myelope

288 Mitochondrial-specific carbonylation was increased acutely (48 h) and chronical

289 cts in the primary olfactory system, protein carbonylation was increased in the olfactory bulb of age

290 A 4-fold increase in protein carbonylation was measured within 15 min of initiating p

291 ctedly, the oxidative DNA damage and protein carbonylation was more severe in the DeltatrxC mutant th

292 Considerable carbonylation was observed in the digestive tract, espec

293 ce an increase in protein post-translational carbonylation was observed.

294 Protein carbonylation was significantly increased in T24 cells t

295 Because aldehydes are important mediators of carbonylation, we explored the immunomodulatory properti

296 tochondrial density, ATP content and protein carbonylation were measured in cardiac muscle.

297 d loss of CcO activity and increased protein carbonylation, which was accompanied by a decline in the

298 clopride, for the dopamine D2/D3 receptor by carbonylation with excellent radiochemical purity and yi

299 N-(o-bromoaryl)amides by palladium-catalyzed carbonylation with paraformaldehyde as the carbonyl sour

300 es to delineate the physiochemical impact of carbonylation yielded channels with enhanced or reduced