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1 LMP-1's critical effector domains (i.e. the carboxy-terminus).
2 rypsin digestion sites of both the amino and carboxy terminus.
3 a functionally important RING domain at its carboxy terminus.
4 oteins and proteins tagged at their amino or carboxy terminus.
5 bstitutions for the aromatic residues in the carboxy terminus.
6 repeat (TR) region of the genome through its carboxy terminus.
7 in and four Kruppel-like zinc fingers at the carboxy terminus.
8 e of the amino terminus of EpoB and the EpoA carboxy terminus.
9 parS that contact the ParB protein near the carboxy terminus.
10 ts amino terminus and a kinase domain in its carboxy terminus.
11 d established a Golgi targeting motif at the carboxy terminus.
12 binding pocket in helices 2 and 3 of Pab1p's carboxy terminus.
13 product that deletes 50 amino acids near the carboxy terminus.
14 n the HMG-like DNA binding domain and at the carboxy terminus.
15 s, and a predicted coiled-coil domain at the carboxy terminus.
16 the sole cysteine residue located within the carboxy terminus.
17 lting in the loss of 17 amino acids from the carboxy terminus.
18 wl', has been located to the large cytosolic carboxy terminus.
19 was present between residue 75 and the pilin carboxy terminus.
20 sing an apparently innocuous change near its carboxy terminus.
21 a CCT (CO, CO-Like, TOC1) domain near their carboxy terminus.
22 sphopeptide sequence in the highly conserved carboxy terminus.
23 of an alpha-chiral, aromatic residue on the carboxy terminus.
24 pendent on phosphorylation of the receptor's carboxy terminus.
25 its leucine-rich repeat (LRR) domain and its carboxy terminus.
26 IK (AAP2BR5), from the amino terminus to the carboxy terminus.
27 coding region at C329, Q330, or Y331 in the carboxy terminus.
28 lexed alone with an IQ domain on the channel carboxy terminus.
29 el of the predicted structured region of the carboxy terminus.
30 ion of three serine residues in the receptor carboxy terminus.
31 nB substitutions in four regions of the TonB carboxy terminus.
32 ls between the ExbD transmembrane domain and carboxy terminus.
33 ucture is disordered in the highly conserved carboxy-terminus.
34 d atypically near the amino- rather than the carboxy-terminus.
35 ronectin type-III domains, and a hydrophobic carboxy-terminus.
36 represented by the crystal structure of the carboxy-terminus.
37 ly specific to SspH2 and was mediated by its carboxy-terminus.
38 hanism for all domains except for the distal carboxy-terminus.
39 f nucleotide, Hsp90 is dimerized only at the carboxy-terminus.
40 l nonamer core region at both the amino- and carboxy-terminus.
41 e 75-kd SirT1 fragment was found to lack the carboxy-terminus.
42 r Mad is activated by phosphorylation at its carboxy-terminus.
43 terozygous frameshift mutation affecting the carboxy-terminus (439fs) of perilipin 1 in two unrelated
44 ed amphiphilic repression (EAR) motif at the carboxy terminus abolishes BZR1's abilities to regulate
45 t its amino terminus and a SET domain at the carboxy terminus, abolishes H3 Lys-4 methylation in fiss
46 an ubiquitin-association (Uba) domain at the carboxy terminus, ACK1 binds to both poly- and mono-ubiq
47 el CLH-3b is reduced by phosphorylation of a carboxy-terminus "activation domain," which disrupts its
48 II (hCA II) nor fusing hCA II to the NBCe1-A carboxy terminus affects background-subtracted NBCe1 slo
50 green fluorescent protein (EGFP) tags at the carboxy terminus, all transcript variants can be correct
51 ons between the functionally critical distal carboxy terminus alpha-helix (H6) and the proximal struc
54 al of 6 residues beginning with L-Glu at the carboxy terminus and alternating Neu2en and L-Glu residu
55 domain to a conserved sequence at the VP1/2 carboxy terminus and demonstrated that this domain suffi
56 , cysteines 754 and 759, is located near the carboxy terminus and is thought to reduce the cystine in
57 al changes that result in an exposure of the carboxy terminus and its insertion into the lipid phase.
58 sults in the loss of 17 amino acids from the carboxy terminus and renders the envelope protein fusion
59 ber protein on ligands incorporated into its carboxy terminus and thus limited the range of potential
60 not the Delta102-139 protein, binds the p53 carboxy-terminus and diminishes its ubiquitination and n
63 one near the amino terminus and one near the carboxy terminus, and a large intervening loop that is p
64 nnel have focused on the large intracellular carboxy terminus, and much evidence supports the hypothe
65 leucine-glutamine (IQ) domain on the channel carboxy terminus, and subsequent Ca(2+) binding to this
66 Together, the data show that P, M, and the F carboxy terminus are sufficient for robust viral protein
69 ining this sequence that carry biotin on the carboxy terminus, as well as a photoactivated cross-link
70 imarily at two sites on the enzyme, with its carboxy terminus at the active site and with its amino-t
72 s a bipartite mediator nuclear export as the carboxy terminus binds HDA and the amino terminus itself
73 Rad1 is independent of Claspin and the Rad9 carboxy terminus, both of which are required for Chk1 ph
74 rylation of S477 and T479 at the Akt extreme carboxy terminus by cyclin-dependent kinase 2 (Cdk2)/cyc
75 and the TonB transmembrane domain, the TonB carboxy-terminus can form a meta-stable high-energy conf
76 located in the amino terminus and one in the carboxy terminus, can independently alter both the level
77 ing of the kinase-interacting regions of the carboxy terminus combined with structural modeling provi
78 -turn-helix (HTH) DNA-binding domain and the carboxy terminus consists of a dimerization domain with
79 elices designated "A-R" and an intracellular carboxy-terminus containing two cystathionine-beta-synth
80 0 throughout its first 551 residues, but its carboxy terminus contains a glycine/arginine-rich domain
84 tified based on ability to interact with the carboxy terminus (CT) of PABP in yeast two-hybrid and in
86 tins, hybrid compounds composed of 3 and the carboxy terminus dipeptides of dolastatin 10, or the dol
87 elongs to the Nedd4-like homologous to E6-AP carboxy terminus domain family of E3 ubiquitin ligases,
89 on between its HECT (homologous to the E6-AP carboxy terminus domain) and two central WW domains.
90 pecific loss of the HECT (homologous to E6AP carboxy terminus) domain E3 ubiquitin ligase Ube3a/E6AP.
91 show a role for the HECT (homologous to E6AP carboxy terminus) E3 ubiquitin ligase WWP-1 as a positiv
92 ll region rich in acidic residues within the carboxy terminus eliminated both the cleavage and nuclea
94 cdc34) ubiquitin-conjugating enzyme, and its carboxy terminus expresses a ubiquitin ligase activity d
97 n of a splice variant of REST that lacks the carboxy terminus has been associated with neuronal tumou
100 sesses a distinctive amino acid motif at its carboxy terminus, including a terminal phenylalanine, wh
101 uclein molecules, and a close amino terminus-carboxy terminus interaction within single alpha-synucle
102 ith the cryptic Polo box of Plk4 whereas the carboxy terminus interacts with the centriolar protein S
103 tional crosstalk between the pore region and carboxy terminus, involved in Ca(2+)-calmodulin-mediated
105 erminus, but a second function involving the carboxy terminus is also required for countering host ce
106 s PKC-dependent phosphorylation of the Kv7.5 carboxy terminus is associated with a reduction in PIP(2
109 fferentiating osteoblasts and that the Runx2 carboxy terminus is necessary for maximal repression of
110 lation on tyrosines 421, 466, and 482 in the carboxy terminus is required for cell movement and metas
111 est that the essential function of the VP1/2 carboxy terminus is to anchor the VP1/2 tegument protein
112 apsids via their amino terminus, whereas the carboxy terminus is unstructured and therefore may bette
113 r provide evidence that the CSF-1 receptor's carboxy-terminus is a substrate for autophosphorylation.
114 n, there is evidence that the CSF-1 receptor carboxy-terminus is involved in down regulation of the r
117 analog (TP3982) was synthesized to harbor a carboxy-terminus lysine (Lys) residue separated from VIP
119 gh the all-Ala Ser(16) His(20) TMD, the TonB carboxy terminus might fold so rapidly that disulfide-li
120 ese data together with the existing Na(V)1.5 carboxy terminus nuclear magnetic resonance structure, w
121 t fusion of domain 3 of the N protein to the carboxy terminus of a heterologous protein caused it to
122 dentify clusters of basic amino acids in the carboxy terminus of AAP from AAV serotype 2 (AAV2) that
124 Here we show that the soluble cytosolic carboxy terminus of an oligomeric ammonium transporter f
127 ontaining the amino terminus of CETP and the carboxy terminus of BPI did not retain any observable CE
129 chimaeras, we demonstrate that the conserved carboxy terminus of CENP-A is necessary and sufficient f
131 ity of a stretch of basic amino acids in the carboxy terminus of Chp and that the basic amino acids w
133 script stability and by restoring the native carboxy terminus of Cre, resulting in a five- to tenfold
135 ce has been mapped to the well-characterized carboxy terminus of E3L, which contains a conserved doub
136 e proteasome, and an interaction between the carboxy terminus of E6 and the PDZ domain of PTPN3.
137 e PDZ domain-binding motif (-X-T-X-V) at the carboxy terminus of E6 is essential for targeting PDZ pr
138 ed by engineering cysteine residues into the carboxy terminus of each STAT molecule, allowing a hypot
139 in recruiting cyclin A complexes, while the carboxy terminus of EBNA3C is necessary for the function
140 this report we demonstrate that although the carboxy terminus of EBNA3C predominantly regulates cycli
142 Cyclin A interacted with a region of the carboxy terminus of EBNA3C, shown to be important both f
143 leting a single amino acid from the amino or carboxy terminus of either peptide markedly reduced IFN-
145 Removal of three lysine residues from the carboxy terminus of ErpP significantly reduced binding o
149 a Gbetagamma inhibitor peptide derived from carboxy terminus of G protein-coupled receptor kinase 2
152 and carboxy-terminal halves of gp120 and the carboxy terminus of gp41 contributed to the neutralizati
153 Vpx binding domain of SAMHD1 is fused to the carboxy terminus of green fluorescent protein (GFP) and
155 Removal of a PDZ domain-binding motif at the carboxy terminus of hH1 did not alter the PKA response.
157 asing the stability of Smad3 in an E3 ligase carboxy terminus of Hsc70-interacting protein-dependent
160 A critical mediator of this mechanism was carboxy terminus of Hsp70-interacting protein (CHIP), a
163 e chimera containing the TD of KCNQ1 and the carboxy terminus of KCNQ4 yielded current density 10- or
164 ntrast to previous models, we found that the carboxy terminus of Ku80 is not absolutely required for
166 ed fluorescent protein fused in frame at the carboxy terminus of M [MmRFP]) at the G-L gene junction,
167 dence that mapped interactions with N to the carboxy terminus of M, it was not possible to define a s
169 terminus of NA from the PR8 strain with the carboxy terminus of NA from VN1203, the surface epitopes
170 analysis suggests that large portions of the carboxy terminus of NS5A are in an unfolded and disorder
172 mutagenesis experiments determined that the carboxy terminus of p28 is not required for its interact
175 re mediated by a conserved region within the carboxy terminus of perilipin 1 that binds and stabilize
176 Chimeric proteins generated by fusing the carboxy terminus of perilipin 1 to the amino terminus of
179 omplex reveals the complete unfolding of the carboxy terminus of Prx, and its unexpected packing onto
181 gnaling complex exists in the absence of the carboxy terminus of Rad9 and that this carboxy-terminal
182 s is consistent with the hypothesis that the carboxy terminus of Rex-2 contains a novel domain that i
188 no terminus and a shorter alpha-helix at the carboxy terminus of Scm3(CBD) wraps around the Cse4-H4 d
190 acts with Sgt1p and, in combination with the carboxy terminus of Sgt1p, regulates the interaction bet
191 the Tyr208Asn amino acid substitution in the carboxy terminus of SHP-1 (referred to as Ptpn6(spin) mi
192 t, co-expression of GFP-tagged Orai with the carboxy terminus of Stim as a cytosolic protein to activ
195 d seven sites in the proline-rich region and carboxy terminus of tau by amino acid substitution.
197 ave inserted the IgG-binding Z domain at the carboxy terminus of the coat protein and coexpressed thi
198 uded an unusual series of amino acids at the carboxy terminus of the core protein unlike that seen in
199 iciently cleaves Stp1 even when fused to the carboxy terminus of the endoplasmic reticulum (ER) membr
200 hat harbored a 1.2-kb insertion spanning the carboxy terminus of the envelope glycoprotein 1 (E1), th
201 04305) was homologous to the non-DNA-binding carboxy terminus of the Escherichia coli Rob transcripti
202 ioning of the NC peptide is conserved at the carboxy terminus of the Gag protein among most long term
204 -helical coiled-coil rod region--towards the carboxy terminus of the heavy chain--has unusual structu
205 ch as PMS1, MLH3 and MBD4, we identified the carboxy terminus of the human c-MYC proto-oncogene as an
206 A conserved amphipathic alpha-helix in the carboxy terminus of the myogenic bHLH proteins has disti
207 vector containing a six-histidine tag on the carboxy terminus of the NqrF subunit, the last subunit i
208 tion is enhanced by a positive charge at the carboxy terminus of the peptide, which triggers an inwar
212 of interactions, one with the phosphorylated carboxy terminus of the receptor and the other with its
216 and E3 three-enzyme cascade, which links the carboxy terminus of ubiquitin to the epsilon-amino group
217 s study is the first to demonstrate that the carboxy terminus of US28 controls US28 signaling in the
218 s to a conformational region centered on the carboxy terminus of V4, and the epitope(s) of CG-III ant
220 sequences on the progressive deletion of the carboxy-terminus of alpha-syn in regulating fibril forma
224 rylated (hp) Tau and to E3 ubiquitin ligase, carboxy-terminus of heat shock-70 interacting protein.
225 gnaling of the nucleotide-bound state to the carboxy-terminus of Hsp82, or regulating Hsp82-Cpr6 inte
226 ions have suggested instead that in vivo the carboxy-terminus of intact TonB is dynamic and flexible.
227 ine based signal (330YSKF333) located in the carboxy-terminus of Kir6.2 and that SUR1 has no direct r
228 hat phosphorylation of kNBC1-Ser(982) in the carboxy-terminus of kNBC1 (kNBC1-Ct), by cAMP-protein ki
229 roteins bind to an acidic LXXLL motif at the carboxy-terminus of MAML1 and repress transactivation by
230 c fragment, a 10 amino acid peptide from the carboxy-terminus of proSP-B (SPTGEWLPR), from the circul
231 ns Ser119, Ser130, Thr132, and Ser138 in the carboxy-terminus of PTHrP and are associated with the ph
234 nd on the binding of calmodulin (CaM) to the carboxy-terminus of the A(2A) receptor in the A(2A)-D(2)
236 These tandem domains are attached to the carboxy-terminus of the cytolytic domain and contain a b
237 of the CAAX box from the git11 Ggamma to the carboxy-terminus of the git5 Gbeta partially suppresses
238 n binding (Fab) (scFab) format, in which the carboxy-terminus of the light chain is linked to the ami
239 ropose that alteration and elongation of the carboxy-terminus of the protein has a dominant-negative
240 le pool is signaled by an element within the carboxy-terminus of the protein, and is a cell-specific
242 opes (neoepitope from cleavage of CII [C2C], carboxy-terminus of three-quarter peptide from cleavage
243 The phenotypic results suggested that the carboxy-terminus of TonB was a flexible and dynamic doma
249 ein domain to either the amino terminus, the carboxy terminus, or to both termini of two small knotte
252 The site of CaM action within the channel carboxy terminus overlaps with that of the KCNQ opener N
255 eas deletion of the S. Typhimurium flagellin carboxy-terminus prevented caspase-1 maturation only.
256 cated RHA peptide that can bind to the BRCA1 carboxy-terminus prevents normal BRCA1 function, such as
259 lation of cortactin tyrosine residues in the carboxy terminus requires the aminoterminal domain and R
260 These frameshifts often create cationic carboxy-terminus residues that replace hydrophobic amino
261 Here, the importance of the cytoplasmic ExbB carboxy terminus (residues 195 to 244) was evaluated by
262 1C and some of the substitutions nearest the carboxy terminus spontaneously formed disulfide cross-li
263 When the crystal structure of a dimeric TonB carboxy-terminus subsequently became available, we obser
264 otein interaction domain of gp32 (the acidic carboxy-terminus), suggesting that a specific interactio
266 the HAND-SANT-SLIDE (HSS) domain at the ISWI carboxy terminus that binds linker DNA, needed for ISWI
267 ave been identified within the intracellular carboxy terminus that can activate NF-kappaB, C-terminus
269 A peptide corresponding to a region of the carboxy terminus that is conserved in Cx36 and its two t
270 (EGFR) upon EGF stimulation via a region at carboxy terminus that is highly homologous to Gene-33/Mi
271 ins a tethered cluster-binding domain at its carboxy terminus that moves in and out of the active sit
272 , we focus on a 57-residue domain within the carboxy-terminus that is a possible PIP(2) binding site.
273 hen combined with W213C or F202C in the TonB carboxy terminus, the TonBDelta7 deletion did not preven
274 -regulate conformational changes at the TonB carboxy terminus through the all-Ala Ser(16) His(20) TMD
276 f amino acids 136 to 290 and is fused at the carboxy terminus to enhanced green fluorescent protein (
277 ioactive peptides require amidation of their carboxy terminus to exhibit full biological activity.
279 n integral membrane protein that exposes its carboxy-terminus to the intermembrane space and exists i
281 G contains a glycine and arginine-rich (RGG) carboxy terminus typically found in vertebrate nucleolin
285 ma-tubulin was specific, and function of the carboxy terminus was necessary for this reaction; trunca
287 or both beta(1)- and beta(2)AR, the receptor carboxy-terminus was uniquely responsible for scaffold i
289 n a yeast two-hybrid screen with the InsP3R1 carboxy terminus, we isolated Htt-associated protein-1A
291 nteractions between that region and the TonB carboxy terminus were identified by examining 270 combin
292 harged residues 104, 105 and 114, 115 in the carboxy-terminus were implicated in this reduced aggrega
293 us to vertebrate Nopp140 particularly in its carboxy terminus, whereas Nopp140-RGG contains a glycine
294 ometer distances after 1) truncations of the carboxy terminus, which contains a C-terminal PDZ (PSD95
295 TtsA depends on a discrete domain within its carboxy terminus, which targets the enzyme to the bacter
296 mia virus (Mo-MuLV) Gag protein has a unique carboxy terminus with a highly charged arginine-rich seq
297 the data suggest that the interaction of Cbl carboxy terminus with CIN85 has a minor and a redundant
298 ar magnetic resonance structures of the TonB carboxy terminus with conformational changes and mutant
299 nt roles in cocrystal structures of the TonB carboxy terminus with OM transporters BtuB and FhuA.
300 h a nuclear localization signal fused to the carboxy terminus (XAP2-NLS) was utilized to test whether