ライフサイエンスコーパス: carboxylic acid

1 es (mero166, azide; mero167, alkyne; mero76, carboxylic acid).

2 amine group ( N-acylation with aldehydes and carboxylic acids).

3 azole moiety as a bioisostere for the distal carboxylic acid.

4 ediated by phenylsilane in the presence of a carboxylic acid.

5 ilable reagents without preactivation of the carboxylic acid.

6 e phenazine derivatives, such as phenazine-1-carboxylic acid.

7 it with (1S,3R,4S)-3,4-dihydroxycyclohexane carboxylic acid.

8 ns bearing a xanthene backbone and a pendant carboxylic acid.

9 the presence of a primary ammonium salt or a carboxylic acid.

10 l azoliums for the formation of ketones from carboxylic acids.

11 ding aldehydes, ketones, esters, amides, and carboxylic acids.

12 es used for amide bond synthesis: amines and carboxylic acids.

13 H substrates, such as unactivated esters and carboxylic acids.

14 lity of Kochi's oxidative decarboxylation of carboxylic acids.

15 which further undergoes amide coupling with carboxylic acids.

16 iberate high-energy carbocations from simple carboxylic acids.

17 naerobically digested to produce short-chain carboxylic acids.

18 ons and conjugate additions with unsaturated carboxylic acids.

19 used as coupling partners to provide chiral carboxylic acids.

20 d and 2d did not give the corresponding C(3)-carboxylic acids.

21 ate as an oxidizing agent for perfluoroalkyl carboxylic acids.

22 mary alcohols in lignin to the corresponding carboxylic acids.

23 and selective synthesis of hydrocarbons from carboxylic acids.

24 e NAD(+)-dependent oxidation of aldehydes to carboxylic acids.

25 rides can be generated in situ directly from carboxylic acids.

26 chment of aliphatic groups unassociated with carboxylic acids.

27 parent acid, thus providing a route to many carboxylic acids.

28 xidation of aldehydes to their corresponding carboxylic acids.

29 phile classes, including azoles, amines, and carboxylic acids.

30 ytic processes for producing biomass-derived carboxylic acids.

31 H olefination of ketone derivatives and free carboxylic acids.

32 r (1R,3S,4S)-3-amino-4-fluoro cyclopentane-1-carboxylic acid (1), in this work, we rationally designe

33 inhibitor, 1,4-dihydrophenonthrolin-4-one-3-carboxylic acid (1,4-DPCA/hydrogel), to promote regenera

34 mino-3-fluoro-4-(fluoro-(18)F)cyclopentane-1-carboxylic acid ([(18)F]28) have been prepared in 10 and

35 mino-3-fluoro-4-(fluoro-(18)F)cyclopentane-1-carboxylic acid ([(18)F]9) and (1S,3S,4R)-1-amino-3-fluo

36 his deterrence is based on the feces-emitted carboxylic acids 3-methylpentanoic acid and hexanoic aci

37 oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid (43d), showing promising antitumor activ

38 cluding pyocyanin (PYO), 5-methylphenazine-1-carboxylic acid (5-MCA), and 1-hydroxyphenazine (OHPHZ),

39 rfluorononanoic acid), and 6:2 fluorotelomer carboxylic acid (6:2 FTCA).

40 hree US samples, where the 7:3 fluorotelomer carboxylic acid (7:3 FTCA) was prevalent.

41 he beta-lactam antibiotic, 1-carbapen-2-em-3-carboxylic acid (a carbapenem).

42 deprotection for a substrate that contains a carboxylic acid, a known QD-binding group, is accelerate

43 iated stabilization of 1-aminocyclopropane-1-carboxylic acid (ACC) synthases (ACSs), the rate-limitin

44 the ethylene precursor 1-aminocyclopropane-1-carboxylic acid (ACC) was found to promote the emergence

45 s immediate precursor, 1-aminocyclopropane-1-carboxylic acid (ACC), is a non-proteinogenic amino acid

46 lear ethylene precursor (aminocyclopropane-1-carboxylic acid, ACC) peak before veraison.

47 -N formation that proceeds through a cascade carboxylic acid activation, acyl azide formation, Curtiu

48 cts with CO(2) to generate the corresponding carboxylic acid after protonation.

49 ylic acid (tACBC)(n) with N-aminoazetidine-2-carboxylic acid, an 8-helical topology is shown to domin

50 Several 3,4-dihydroxycyclohexane carboxylic acid analogues can be employed for chain rele

51 ,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid analogues with up to a 1000-fold increas

52 d for the conductance of TPA bridged through carboxylic acid anchoring groups (3.8 x 10(-4)-3.2 x 10(

53 catalyze the hydrolysis of esters to form a carboxylic acid and alcohol.

54 esign due to not only their bioisosterism to carboxylic acid and amide moieties but also to their met

55 A Ugi four-component reaction with indole-2-carboxylic acid and an aniline followed by a Pd-catalyze

56 size a series of enantiopure, pinene-derived carboxylic acid and dimer ester homologues.

57 hed beta-thio-alpha-hydroxy and alpha-chloro carboxylic acid and ester building blocks by diazotizati

58 not impair its ability to act as an ordinary carboxylic acid and to efficiently protonate physiologic

59 oxidants for the construction of esters from carboxylic acids and alcohols in the presence of stoichi

60 NMVOCs were largely dominated by small carboxylic acids and alcohols, and furans.

61 In these films, residual carboxylic acids and amines influence permeability and s

62 cross-coupling of vinyl boronic esters with carboxylic acids and aryl iodides is described.

63 tereoisomers of tetrasubstituted azetidine-2-carboxylic acids and derivatives that possess three chir

64 d NSSM, respectively, which mainly belong to carboxylic acids and derivatives, polyketides and fatty

65 sing the measured (-)ESI efficiencies of the carboxylic acids and dimer esters as more representative

66 ity of the reaction in the presence of other carboxylic acids and its utility in the functionalizatio

67 ncluded amino acids, fatty acid derivatives, carboxylic acids and phenolic compounds.

68 ranges attributable to the deprotonation of carboxylic acids and phenols.

69 crease in absorption due to deprotonation of carboxylic acids and phenols.

70 tural sources and consumer products, such as carboxylic acids and plasticizers.

71 xidation of residual carbon atoms first into carboxylic acids and then volatile carbon species, while

72 d variants often require a pre-activation of carboxylic acids and/or employment of costly transition-

73 -arginine, S-palmitoyl-cysteine, pyrrolidone-carboxylic-acid and SUMOylation sites.

74 ecane-1-(methane phosphonic acid)-8-(methane carboxylic acid) and a polyethylene glycol 4 linker, at

75 s relies upon one high-availability reagent (carboxylic acids) and one low-availability reagent (orga

76 e present in HULIS, oxygen-containing (i.e., carboxylic acids) and reduced-nitrogen-containing organi

77 ) values of phenols, aliphatic, and aromatic carboxylic acids, and ketoacids.

78 s revealed methyl ketones, alcohols, esters, carboxylic acids, and nitrogen- and sulfur-containing co

79 ulation between aryl iodides and unsaturated carboxylic acid anhydrides.

80 Aromatic carboxylic acids are found to undergo reactions with iso

81 Ethers derived from C(2) and C(4) carboxylic acids are identified as advantaged fuel candi

82 These renewable carboxylic acids are involved in the synthesis of releva

83 carbonyl derivatives, such amides, ester and carboxylic acids, are presented in a systematic manner.

84 alyzed conjunctive cross-coupling of alkenyl carboxylic acids, aryl iodides, and aryl/alkenyl boronic

85 king isatoic anhydride-8-amide from isatin-7-carboxylic acid as a tool to easily produce a range of q

86 tified a methyl substitution adjacent to the carboxylic acid as an appropriate means to accomplish fa

87 ent obtained from the oxidation of ferrocene carboxylic acid as the electrochemical probe.

88 he developed methodology rendered the use of carboxylic acids as a direct surrogate of primary amines

89 The reaction uses naturally abundant organic carboxylic acids as carbon sources, readily prepared azi

90 An alternative approach is to use ubiquitous carboxylic acids as starting materials and perform a dec

91 commodates a large variety of heteroaromatic carboxylic acids as well as olefins, and facilitates a d

92 turated aliphatic hydrocarbons, esters, free carboxylic acids, as well as minor amounts of amides and

93 rating the required functional groups (e.g., carboxylic acid, azide, or alkyne) were synthesized and

94 containing compounds, starting from a single carboxylic acid, based on the selection of the nucleophi

95 ibe the design, synthesis, and evaluation of carboxylic acid-based ACC inhibitors with organic anion

96 Besides alkyl carboxylic acids, benzylic C(sp(3) )-H bonds also could

97 our betalains, named indicaxanthin, indoline carboxylic acid-betacyanin, phenylalanine-betaxanthin, a

98 classes, including phenols, diols, silanols, carboxylic acids, boronic acids, and phosphoric acids, w

99 DFT studies, aided by crystal structures of carboxylic acids bound by the catalyst, point to a plaus

100 Starting from simple carboxylic acid building blocks, this modular sequence e

101 roach enables conversion of a broad range of carboxylic acids by filling up the vacant substrate acce

102 chromones, 3-formylchromones, and chromone-3-carboxylic acids by means of visible-light photoredox ca

103 cyclic and heterocyclic amines directly with carboxylic acids, by-passing their preactivation as redo

104 simultaneously transformed to perfluoroalkyl carboxylic acids (C2-C7 PFCAs) of different chain length

105 nyl complexes, a chelator was selected whose carboxylic acids can easily be converted into various de

106 hat a Mn-catalyzed C-H oxidation directed by carboxylic acids can overcome these challenges to yield

107 degrees alcohol/alcohol oxidase (AO) or (ii) carboxylic acid/carboxylic acid reductase (CAR) to affec

108 We report that a readily accessible chiral carboxylic acid catalyst exerts control over asymmetric

109 The flexibility of the hydroxyl carboxylic acid catalyst leads to significant difference

110 The high acidity of the carboxylic acid catalyst, which exceeds that of the well

111 ism of the asymmetric BINOL-derived hydroxyl carboxylic acid catalyzed allylboration of benzaldehyde

112 dansyl aniline (DA), and 7-hydroxycoumarin-3-carboxylic acid (CC)-are mixed to produce almost pure wh

113 ion in the number of glomeruli responding to carboxylic acids-chemicals associated with microbial act

114 ve of all-cis-2-amino-3-hydroxycyclobutane-1-carboxylic acid, cis-trans stereoisomers are obtained fo

115 Herein we report that pendant carboxylic acids, combined with bulky monophospine ligan

116 The construction of carboxylic acid compounds in a selective fashion from lo

117 cage is capable of co-encapsulating multiple carboxylic acid containing guests in its cavity, and the

118 utility of the E-RANSY method by extracting carboxylic acid containing metabolites from human urine,

119 ce of two alpha-methyl groups; (2) aliphatic carboxylic acids containing alpha-hydrogens are compatib

120 this procedure will facilitate the access to carboxylic acids containing drugs and accelerate early (

121 s for enantiodiscrimination of alpha-racemic carboxylic acids containing tertiary or quaternary stere

122 strategy can be generalized to a variety of carboxylic acid-containing drug structures that satisfy

123 s system (CNS) therapeutics, especially with carboxylic acid-containing drugs.

124 re widely used to decrease volatilization of carboxylic acid-containing herbicides including dicamba.

125 -based complex, treatment of a hydroxy- or a carboxylic-acid-containing olefin with commercially avai

126 dihydro-5-(2-methoxyethoxy)-4-oxocinnoline-3-carboxylic acid; Croisor 100) to 27 genotypes in replica

127 lites generated from energy expenditure, tri-carboxylic acid cycle, tocopherol, polyamine metabolism,

128 Such flipping was absent when the carboxylic acid derivative of the sensitizer was utilize

129 such, the invention of new reactions between carboxylic acid derivatives and amines that strategicall

130 ubstituted piperidines with aryl, alkyl, and carboxylic acid derivatives at multiple different sites.

131 The first synthesis of isoxazole-4-carboxylic acid derivatives by domino isoxazole-isoxazol

132 sformations that allow for the conversion of carboxylic acid derivatives to functional groups bearing

133 The reaction of carboxylic acid derivatives with amines to form amide bo

134 Carboxylic acid derivatization produces a broad range of

135 ide esters (primary, secondary, and tertiary carboxylic acid derived), several saturated and unsatura

136 method allows unprecedented direct access to carboxylic acids derived from beta,beta-trisubstituted a

137 droxyphenyl)propanoic and 5-oxopyrrolidine-2-carboxylic acids, diacetyl, acetoin, and an unidentified

138 Protein backbones and pyridine-carboxylic acids dominated this discrimination and might

139 and epsilon-lactonization reactions of free carboxylic acids enabled by a novel cyclopentane-based m

140 Our results show that carboxylic acids enhance the OP(AA) and OP(*OH) by TMs w

141 ts in the synthetic sequence relative to the carboxylic acid ester.

142 the intermolecular radical C-H amination of carboxylic acid esters with organic azides via Co(II)-ba

143 ketone synthesis that couples two different carboxylic acid esters, N-hydroxyphthalimide esters and

144 provide the transport steps for amino acids, carboxylic acids, fatty acids, cofactors, inorganic ions

145 oved applicable to a variety of (hetero)aryl carboxylic acid fluorides as well as diverse diboron rea

146 N-alkyl pyridinium salts with in situ formed carboxylic acid fluorides or 2-pyridyl esters under redu

147 nickel-catalyzed decarbonylative coupling of carboxylic acid fluorides with diboron reagents to selec

148 scent bis-styryl-benzothiadiazole (BTD) with carboxylic acid functional groups (X-34/Congo red analog

149 Metabolites are enriched in carboxylic acid functional groups and depleted of ketone

150 -COOH monomer, the nanofibrous structure and carboxylic acid functionalisation of Nano-PEDOT-COOH wer

151 All the materials, except the carboxylic acid functionalised one, offer high PPO loadi

152 ur new VoltageFluor derivatives that possess carboxylic acid functionality for simple conjugation to

153 etraethylene glycol groups terminated with a carboxylic acid functionality were introduced to the CD'

154 The need for an ester versus carboxylic acid-functionalized coupling partner is also

155 have been developed through the addition of carboxylic acid-functionalized polycarbonate block copol

156 Taken together, carboxylic acid-functionalized polycarbonates represent

157 s, consisting of poly(ethylene oxide) (PEO), carboxylic acid-functionalized polyphosphoester (PPE), a

158 bearing three phenol groups and three other carboxylic acid functions, each of these groups on the a

159 and simultaneous emission involving coumarin carboxylic acid, furocoumarin and dansyl aniline played

160 nge of 15.6 +/- 3.7 to 70.0 +/- 9.5 nm and a carboxylic acid group density from 0.03 to 0.18 mumol cm

161 It is proposed that the carboxylic acid group directs the isocyanate electrophil

162 was synthesized via an amide linkage between carboxylic acid group of HA and amine group of dopamine.

163 The designed linker molecule has a carboxylic acid group to bind with a metal surface, and

164 Coordination of the carboxylic acid group to the bulky Mn complex ensures th

165 methyl-substituted alkenes with a hydroxy or carboxylic acid group were thus prepared in 51-97 % yiel

166 ransformation of the isoxazole moiety into a carboxylic acid group, thus opening access to dicarboxyl

167 ter was observed with a surfactant bearing a carboxylic acid group, which anchored amine monomers ver

168 cular orientation via dehydrogenation of the carboxylic acid group, which we confirmed using polariza

169 nity, piperidine-based chemical tags to each carboxylic acid group.

170 ce with a tunable 3D nanofibrous network and carboxylic acid groups (i.e. Nano-PEDOT-COOH) via contro

171 ysis can be explained by the presence of two carboxylic acid groups and a tetracyclic structure.

172 udies show that Cu(2+) is coordinated by two carboxylic acid groups and the single amine group on an

173 ling with multi-biorecognition molecules via carboxylic acid groups for the development of a range of

174 Furthermore, the carboxylic acid groups provide an anchoring site for the

175 e functionalities, e.g., hydroxy, amino, and carboxylic acid groups, glucuronidation can occur at any

176 e isomeric metabolites each containing three carboxylic acid groups.

177 th excellent tolerance for amide, ester, and carboxylic acid groups.

178 anic compounds by exploiting their pH-active carboxylic acid groups.

179 se-catalyzed chemoselective hydroboration of carboxylic acids has been developed with a high turnover

180 Different types of carboxylic acids have been included in this review: mono

181 ylate a wide range of aromatic and aliphatic carboxylic acids, have multiple reusability, and are a r

182 ng 3a-hydroxyhexahydropyrrolo[2,3-b]indole-2-carboxylic acid (HPIC) in a single, scalable step with e

183 -4-(perfluoropropan-2-ylidene)cyclopentane-1-carboxylic acid hydrochloride (1) was found to be a sele

184 azole moiety as a bioisostere for the distal carboxylic acid in glutamate receptor agonists.

185 balance between two opposing effects of the carboxylic acid in the reaction mixture: generation of m

186 d use of "dry ozonolysis" to reveal a masked carboxylic acid in the total synthesis of a natural prod

187 of endocyclic enol lactones from unsaturated carboxylic acids in an one-pot procedure.

188 and NRPS-like enzymes activate and transform carboxylic acids in both primary and secondary metabolis

189 h cis- and trans-1,3-disubstituted housane-1-carboxylic acids in diastereoselective manner on up to 8

190 carbons) and functional groups (sulfonic and carboxylic acid) in zebrafish ( Danio rerio) embryo.

191 s and enantioselectivities, affording chiral carboxylic acids including Naproxen, (S)-Flurbiprofen, a

192 is accepting of a broad scope of alkene and carboxylic acids, including challenging ones that produc

193 is displayed, and application of a range of carboxylic acids, including secondary alpha-amino acids,

194 trated for the ligand 4'-hydroxyazobenzene-2-carboxylic acid interacting with avidin protein immobili

195 n was further demonstrated by converting the carboxylic acid into cyclopropyl amine without loss of o

196 ,5-tetrahydro-5-oxo-imidazo[1,2-a]pyridine-7-carboxylic acid (IPCA).

197 hyl-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-carboxylic acid is a natural product found in Dodonaea v

198 alcohols to their corresponding aldehyde or carboxylic acid is one of the most important classes of

199 synthesis of COO-BODIPYs from F-BODIPYs and carboxylic acids is established.

200 oach to the carbon-14 radiolabeling of alkyl carboxylic acids is presented.

201 and hydroalkenylation of unactivated alkenyl carboxylic acids is reported, whereby the ligand environ

202 with diverse functional groups (i.e. amine, carboxylic acid, isocyanate, alkane and pyridine).

203 al group tolerance (phenols, amides, ethers, carboxylic acids, ketones, and acrylic esters).

204 s (furfural and 5-hydroxymethylfurfural) and carboxylic acids (lactic acid, succinic acid, fumaric ac

205 catalysis (BAC), electrophilic activation of carboxylic acids leads to the formation of amides from a

206 nd used for classification of wines based on carboxylic acids levels, which were indirectly related t

207 Medium-chain carboxylic acids (MCCAs) are valuable platform chemicals

208 talysis by an S-adenosylmethionine-dependent carboxylic acid methyltransferase.

209 Pyrene carboxylic acid-modified single-walled carbon nanotubes

210 ar and charged anchor point residues for the carboxylic acid moiety of the agonist in the interhelica

211 Preservation of the terminal carboxylic acid moiety on ODDA-PTX enables binding to HS

212 zation of substrates bearing an alcohol or a carboxylic acid moiety, is highlighted in the context of

213 to the (1S,2R)-2-(aminomethyl)cyclopentane-1-carboxylic acid monomer precursor, which has a cis-confi

214 ear receptor modulators, which often feature carboxylic acid motifs for target engagement, have emerg

215 Naphthenic acids (NAs) are carboxylic acids naturally occurring in crude oils and b

216 6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid o-tolylamide (TM(inh)-23) with 30 nM hal

217 ones and beta-ketoesters (C-H reagents) with carboxylic acids (O-H reagents) was developed.

218 an ester, as the functional precursor to the carboxylic acid of illudinine.

219 terized by a salt bridge between R41 and the carboxylic acid of the inhibitor.

220 Starting with a mixture of activated carboxylic acids of different lengths, iterative cycling

221 Thus, carboxylic acids, once converted to redox-active esters

222 reased over time, and >=C(11) perfluorinated carboxylic acids only seem to level off during the last

223 p (Z) and at the C-terminus carried either a carboxylic acid or an isophthalic acid (Ipa) anchor grou

224 by free radical processes provide access to carboxylic acid or ketone products.

225 PhFOH/BF(3).OEt(2) even in the presence of a carboxylic acid or primary ammonium group.

226 have shown that introducing large amounts of carboxylic acids or ammonium hydroxide to LC eluents pos

227 ed into an aldehyde or ketone (for instance, carboxylic acids or organic carbonate or nitriles) or in

228 lationship (SAR) of antischistosomal ozonide carboxylic acids OZ418 (2) and OZ165 (3).

229 hydration of Hyp to (S)-Delta(1)-pyrroline-5-carboxylic acid (P5C).

230 e metabolites including Delta1-piperideine-6-carboxylic acid (P6C), alpha-aminoadipic semialdehyde (a

231 Phenazine-1-carboxylic acid (PCA) is a broad-spectrum antibiotic pro

232 e synthesized a water-based ink using pyrene carboxylic acid (PCA) through non-covalent pai-pai stack

233 oss; low urocanic acid (UCA) and pyrrolidone carboxylic acid (PCA), both of which are filaggrin break

234 Perfluoroalkyl carboxylic acids (PFCA) in snowpacks display odd-even co

235 Several linear chain perfluoroalkyl carboxylic acids (PFCAs) (C4 to C7) were identified as b

236 ride and sulfate, short-chain perfluorinated carboxylic acids (PFCAs) were identified and quantified

237 yl sulfonic acids (PFSAs) and perfluoroalkyl carboxylic acids (PFCAs) were readily degraded, other st

238 redictor of the enrichment of perfluoroalkyl carboxylic acids (PFCAs) with >=7 perfluorinated carbons

239 s = C(plankton)/C(water)) for perfluorinated carboxylic acids (PFCAs) with five and six carbons (log

240 oefficients, K(mem/w), of six perfluoroalkyl carboxylic acids (PFCAs), three perfluoroalkanesulfonic

241 lfonates (PFSAs, C(4-12)), 10 perfluoroalkyl carboxylic acids (PFCAs, C(4-13)), and perfluorooctane s

242 degradation of emerging perfluoroalkyl ether carboxylic acid (PFECA) pollutants with ultraviolet-gene

243 , trade name GenX) is a perfluoroalkyl ether carboxylic acid (PFECA) that has been detected in waters

244 ge: 1-110 ng/g) and two perfluorinated ether carboxylic acids (PFO(4)DA and PFO(5)DoDA; PFO(5)DoDA ra

245 Protonation to form phosphine carboxylic acid (PH(2) COOH) and functionalization to fo

246 n of reactive intermediates, including mixed carboxylic acid-phosphoric acid anhydrides, for the synt

247 Enzymes that cleave ATP to activate carboxylic acids play essential roles in primary and sec

248 alt hydride occurred in the presence of free carboxylic acid, producing the same alkane enantiomer as

249 the substrate, leading to the corresponding carboxylic acid product for the latter, while the former

250 MNPs) coated with poly (pyrrole-co-pyrrole-2-carboxylic acid) (Py/Py-COOH/MNPs) cross-linked with Ab-

251 of amino acids, as well as into alcohols and carboxylic acids, rapidly and in excellent yields, using

252 we show the unexplored role of the hydroxyl carboxylic acid receptor type 2 (HCAR2) in 2 models of n

253 eimides, M(p) and M(m), each equipped with a carboxylic acid recognition site, results in the formati

254 nonribosomal peptide synthetase (NRPS)-like carboxylic acid reductase (Fub8) in making an aliphatic

255 ated by expanding the substrate scope of the carboxylic acid reductase toward noncognate omega-hydrox

256 ion/transformation of AA to 6-ACA and HMD by carboxylic acid reductases (CARs) and transaminases (TAs

257 alkylation of amines with either alcohols or carboxylic acids represents a mild and safe alternative

258 They bind with proteins where carboxylic acid residues are dominant ligands.

259 drogenation reactions involving chlorine and carboxylic acids, respectively, thus amplifying these at

260 vel cyclodextrin (CD)-based amphiphilic poly(carboxylic acid)s that self-assemble into highly ordered

261 increase of a contribution of aromatic poly(carboxylic acid)s with high conjugation lengths.

262 actions are highly charged and often rich in carboxylic acid side chains(1-5), but the structures of

263 PFAA congeners, summation of perfluoroalkyl carboxylic acids (SigmaPFCAs), and SigmaPFAAs correlated

264 ral imidazoles, we extended our ligands with carboxylic acid substituents toward a polar, water-rich

265 2) [II,III] complexes, featuring unprotected carboxylic acid substituents, with Cu(OAc)(2) .

266 of the same 4-substituted Delta1-pyrroline-2-carboxylic acid substrate, making LmbY and GriH unusual,

267 remote C-H activation reactions of alcohols, carboxylic acids, sulfonates, phosphonates, and amines.

268 In combination with the presence of a carboxylic acid, the electronic features of these compou

269 ophiles in one pot to afford alpha-silylated carboxylic acids, their derivatives, or TBS-substituted

270 fic chemical moieties, namely, allyl, amine, carboxylic acid, thiol, aldehyde, and catechol, were pre

271 Aliphatic alcohols, phenols, carboxylic acids, thiols and sulfonamides were found to

272 nessed to activate nucleoside phosphates and carboxylic acids through catalysis by acid and 4,5-dicya

273 The coupling of an amine with a carboxylic acid to form an amide bond is the most popula

274 Catalytic reduction of carboxylic acid to the corresponding alcohol is a challe

275 The addition of carboxylic acids to allenes was performed with copper ca

276 ed the gamma-C(sp(3) )-H olefination of free carboxylic acids to form diverse six-membered lactones.

277 A method for the annulation of amines and carboxylic acids to form pharmaceutically relevant azahe

278 ght in the presence of acetic acid and other carboxylic acids to generate methyl and alkyl radicals,

279 The method is based on conversion of carboxylic acids to the corresponding organic halides vi

280 production of short-chain alkanes from waste carboxylic acids under mild reaction conditions.

281 e N-acylation of glycosamine with a range of carboxylic acids under physiological reaction conditions

282 cert to decarboxylate alpha-beta unsaturated carboxylic acids using a highly modified flavin cofactor

283 carboxylative functionalization of aliphatic carboxylic acids using N-xanthylamides.

284 tric hydrogenation of alpha,beta-unsaturated carboxylic acids using readily prepared bis(phosphine) c

285 ides using the deoxofluorination reaction of carboxylic acids using XtalFluor-E is described.

286 Phenanthrene carboxylic acid was detected in the phenanthrene-degradi

287 tween an aryl methyl ether and a neighboring carboxylic acid was developed for creating the chromenon

288 of N-hydroxyimides with ketones, esters, and carboxylic acids was achieved employing the di-tert-buty

289 s and (alpha,beta-unsaturated) nitriles from carboxylic acids was realized through oxidative decarbox

290 initial formation of the Castagnoli-Cushman carboxylic acids was shown to be the case, and their dec

291 lation of ortho-iodoallenamides with alkynyl carboxylic acids was studied.

292 fully synthesized, and no over-oxidations to carboxylic acids were detected.

293 2) and VOCs (mainly aldehydes, ketones and a carboxylic acid) were detected as the gaseous products r

294 ess, probably owing to differences in target carboxylic acids (which can bind to the aniline (AN) m-a

295 sm, caused by internal catalysis of the free carboxylic acid, which reversibly forms an activated pht

296 The oxidative coupling of carboxylic acids with liquid ketones and cyclic ethers h

297 one single step, the desired carbon tag into carboxylic acids with no need of structural modification

298 selective C(sp(3) )-H cross-coupling of free carboxylic acids with organoborons has been realized usi

299 luorination of cinnamic and (hetero)aromatic carboxylic acids with sulfur tetrafluoride.

300 , catalyzing the transvinylation reaction of carboxylic acids without losing their original metatheti