ライフサイエンスコーパス: carboxymethyl

1 vatives, with the (64)Cu complex of 4,10-bis(carboxymethyl)-1,4,7,10-tetraazabicyclo[5.5.2]tetradecan

2 , CREKA-Tris(Gd-DOTA)3 (Gd-DOTA (4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecyl gadolinium)

3 carboxylic acid) (CB-TE1A1P) and 2-(4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl)pentanedioic acid (N

4 gh-affinity PET probe, (64)Cu-labeled 11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2] hexadecan

5 cular LLP2A format using (64)Cu-LLP2A-11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

6 synthesis and evaluation of 64Cu-CB-4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

7 CBTE2A (CBTE2A is 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

8 bes the radiolabeling procedure for 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

9 o, whereas 64Cu-CB-TE2A (CB-TE2A is 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

10 cross-bridged macrocyclic chelator 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

11 revealed that the (64)Cu complex of 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

12 ee 4,11-di-pendant arm derivatives: 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

13 -deoxy-3-pyridyldimethylglyoximatocobalt-5-O-carboxymethyl-1,2-O-isop ropylidene-alpha-D-xylofuranose

14 s is based on the presence of 2-amino-3-{[2-(carboxymethyl)-2,5-dihydroxy-1-cyclohex-3-enyl]sulfanyl}

15 , 4-oxalocrotonate tautomerase (4-OT) and 5-(carboxymethyl)-2-hydroxymuconate isomerase (CHMI), and c

16 d by 4-oxalocrotonate tautomerase (4-OT), 5-(carboxymethyl)-2-hydroxymuconate isomerase (CHMI), and m

17 The 2-indolamide (52) and N-(carboxymethyl)-2-indolamide (54) derivatives had improve

18 me, the chemical syntheses of authentic N(6)-carboxymethyl-2'-deoxyadenosine (N(6)-CMdA) and N(4)-car

19 thyl-2'-deoxyguanosine (O(6)-MedG), and N(6)-carboxymethyl-2'-deoxyadenosine (N(6)-CMdA).

20 ethyl-2'-deoxyadenosine (N(6)-CMdA) and N(4)-carboxymethyl-2'-deoxycytidine (N(4)-CMdC), liquid chrom

21 thyl)-2'-deoxyguanosine (N(2)-CEdG) and N(2)-carboxymethyl-2'-deoxyguanosine (N(2)-CMdG) sites.

22 for the simultaneous quantification of O(6)-carboxymethyl-2'-deoxyguanosine (O(6)-CMdG), O(6)-methyl

23 The O(6)-carboxymethyl-2'-deoxyguanosine was previously detected

24 semialdehyde (CHMS) dehydrogenase (CHMSD), 5-carboxymethyl-2-hydroxymuconate (CHM) isomerase (CHMI),

25 es 4-oxalocrotonate tautomerase (4-OT) and 5-carboxymethyl-2-hydroxymuconate isomerase (CHMI).

26 enzymes (4-oxalocrotonate tautomerase and 5-carboxymethyl-2-hydroxymuconate isomerase) that otherwis

27 those of 4-oxalocrotonate tautomerase and 5-carboxymethyl-2-hydroxymuconate isomerase.

28 sociated with individual enzymes including 5-carboxymethyl-2-hydroxymuconate-semialdehyde (CHMS) dehy

29 reference of the enzyme for cyclocreatine (1-carboxymethyl-2-iminoimidazolidine).

30 N-(alpha-methyl-2-nitrobenzyl)urea, N-(alpha-carboxymethyl-2-nitrobenzyl)urea, and N-(alpha-carboxy-2

31 or 5'-O-(dimethoxytrityl) derivatives of 3'-(carboxymethyl)-3'-deoxyribonucleosides that are effectiv

32 The synthesis of 1-(carboxymethyl)-3-(mercaptododecyl)-imidazoliumbromide, a

33 lting alkene gave stereodefined access to 3-(carboxymethyl)-3-deoxy-D-ribofuranose derivatives.

34 A guanylylpyridinol derivative, 6-carboxymethyl-3,5-dimethyl-4-guanylyl-2-pyridinol (3), i

35 18S,21S,24S,27S,30S)-27-(2-carboxyethyl)-21-(carboxymethyl)-30-((2S,3R,4R,5R,6S) -6-((2-(4-(3-F18-flu

36 he iron-guanylylpyridinol (FeGP) cofactor, 6-carboxymethyl-5-methyl-4-hydroxy-2-pyridinol (1) is 3-me

37 ometry of quiescent cells and by 2'-7'-bis[2-carboxymethyl]-5(6)-carboxyfluorescein fluorescence meas

38 Gly-His-Sta-Leu-NH2], and NODA-MPAA is 2-[4-(carboxymethyl)-7-{[4-(carboxymethyl)phenyl]methyl}-1,4,7

39 STING agonists, both 10-carboxymethyl-9-acridanone (CMA) and 5,6-dimethylxanthen

40 -N'-(2-ethyloxyethyl)-N,N'-bis[N' ',N' '-bis(carboxymethyl)acetamido]-1,2-ethanediamine (ABE-DTTA), h

41 S-(Carboxymethyl)-alpha-lactalbumin, a disordered form of t

42 g on fibrillation of four proteins, bovine S-carboxymethyl-alpha-lactalbumin (a disordered form of th

43 orescence probe 6-dodecanoyl-2-[ N-methyl-N-(carboxymethyl)amino] naphthalene, a sensor for the lipid

44 e development of LDTPA (N,N-bis[2-[N',N'-bis(carboxymethyl)amino]- ethyl]-4-amino-L-phenyl-alanine).

45 d ureA DNA fragments by tethering (S)-1{[bis(carboxymethyl)amino]methyl}-2-{4-[(2-bromoacetyl)amino]p

46 eases with (2- inverted question markC2-bis-(carboxymethyl)-amino-5 methylphenoxy]methyl inverted que

47 , 1-{2-[2-[(2-(biscarboxymethyl-amino)ethyl)-carboxymethyl-amino]ethyl]-carb oxymethyl-amino}-acetyla

48 hylamino)-octyl ester (TMB-8) and 2-[(2-bis-[carboxymethyl]amino-5-methylphenoxy)-methyl]-6-methoxy-8

49 thyl inverted question mark-6-methoxy-8-bis-(carboxymethyl)-aminoquinoline tetra-(acetoxymethyl)ester

50 no-5-methylphenoxy)-methyl]-6-methoxy-8-bis [carboxymethyl]aminoquinoline (Quin-2).

51 gregation of Cyanine-1dye in the presence of carboxymethyl amylose (CMA) is described.

52 erformed single-molecule AFM measurements on carboxymethyl amylose, and we found that, in contrast to

53 he gold WEs through functionalization with 4-carboxymethyl aryl diazonium (CMA).

54 lted in excellent yields of anilines; even 2-carboxymethyl aryl nonaflate is effectively coupled with

55 The synthetic derivative of ascochlorin, 4-O-carboxymethyl ascochlorin (AS-6) is an agonist of the nu

56 With an alternative nucleotide, 1-carboxymethyl-ATP, coupled with a mutation that introduc

57 f cationic liposomes prepared from DOTAP and carboxymethyl-beta-cyclodextrin (CD).

58 The distribution coefficients for carboxymethyl-beta-cyclodextrin (CM-beta-CD), degree of

59 The addition of carboxymethyl-beta-cyclodextrin in the running buffer as

60 Overall, the results of this study show that carboxymethyl-beta-cyclodextrin increased lipoplexes' en

61 The addition of carboxymethyl-beta-cyclodextrin to cationic liposomes re

62 The anionic carboxymethyl-beta-cyclodextrin, used to chromatographic

63 e negatively charged pseudostationary phase, carboxymethyl-beta-cyclodextrin.

64 imetic compound, 2-(trimethylsilyl)ethyl 3-O-carboxymethyl-beta-D-galactopyranosyl-(1-->4)-[alpha-L-f

65 The nitrosated carboxymethyl-bovine serum albumin exhibited similar vas

66 with acidified NaNO2 was compared to that of carboxymethyl-bovine serum albumin in which the thiol gr

67 indicated that a non-cysteine residue(s) in carboxymethyl-bovine serum albumin was nitrosated.

68 NaHCO3, and the (63)Zn was then trapped on a carboxymethyl cartridge, washed with water, and eluted w

69 racellular protein and a 20-fold increase in carboxymethyl cellulase activity relative to a wild-type

70 A clone encoding carboxymethyl cellulase activity was isolated during fun

71 lZ represents approximately 95% of the total carboxymethyl cellulase activity.

72 to bind to cellulose and an apparent loss of carboxymethyl cellulase and mannanase activities.

73 e largest, with known activities comprising (carboxymethyl)cellulases, mixed-linkage endo-glucanases,

74 , R237, K259 and E263) increased activity on carboxymethyl cellulose (CM-cellulose), with K259H (in g

75 e divalent cations for monovalent ions, 0.2% carboxymethyl cellulose (CMC) 700 kg mol(-1) as the disp

76 l animals were treated daily with 1 ml of 2% carboxymethyl cellulose (CMC) alone or containing one of

77 ne and of combinations of both enzymes using carboxymethyl cellulose (CMC) and amorphous cellulose (a

78 (MC), hydroxypropyl methylcellulose (HPMC), carboxymethyl cellulose (CMC) and chitosan (CH) coatings

79 ors by blending polyvinyl alcohol (PVA) with carboxymethyl cellulose (CMC) and combining alizarin and

80 Interaction effects between xanthan (X), carboxymethyl cellulose (CMC) and kappa-carrageenan (kap

81 FeS) nanoparticles were prepared with sodium carboxymethyl cellulose (CMC) as a stabilizer, and teste

82 Microcrystalline cellulose (MCC) or carboxymethyl cellulose (CMC) can be used as fat replace

83 Nano-ZnO in combination with carboxymethyl cellulose (CMC) coating was used on pomegr

84 The effects of dithionite and nZVI loadings, carboxymethyl cellulose (CMC) coating, addition of palla

85 a low adhesion to MB-thermally cross-linked carboxymethyl cellulose (CMC) film.

86 a letrozole-induced PCOS group (n = 30) or a carboxymethyl cellulose (CMC) group (n = 6).

87 dium caseinate (NaCAS) and a polysaccharide, carboxymethyl cellulose (CMC) or gum Arabic (GA), to ret

88 MCs, doped with prebiotic growth supporting carboxymethyl cellulose (CMC) polymers, could impact mic

89 al were prepared and embedded in chitosan or carboxymethyl cellulose (CMC) polysaccharides to form ac

90 aterial consisting of commercially available carboxymethyl cellulose (CMC) was evaluated as sampling

91 scale zerovalent iron (nZVI) stabilized with carboxymethyl cellulose (CMC) was performed at an active

92 e polysaccharides (carrageenan, alginate and carboxymethyl cellulose (CMC)) as flocculants was invest

93 les employed were either bare or coated with carboxymethyl cellulose (CMC), a polymer utilized to sta

94 d polymers such as (Chitosan, potato starch, carboxymethyl cellulose (CMC), corn starch and Arabic gu

95 LPI) and a range of anionic polysaccharides [carboxymethyl cellulose (CMC), gum Arabic (GA), alginate

96 zymes were assayed for catalytic activity on carboxymethyl cellulose (CMC), swollen cellulose (SC), f

97 horoughly characterized solutions containing carboxymethyl cellulose (CMC)-stabilized nZVI, bare nZVI

98 h either microfibrillated cellulose (MFC) or carboxymethyl cellulose (CMC).

99 1, crystalline cellulose, and xylan, but not carboxymethyl cellulose (CMC).

100 ic-polycytidylic acid with poly-L-lysine and carboxymethyl cellulose (Hiltonol), a potent TLR3 agonis

101 lowing the injection of nZVI stabilized with carboxymethyl cellulose (nZVI-CMC).

102 ice were p.o. fed with vehicle control (0.5% carboxymethyl cellulose and 0.025% Tween 20 in distilled

103 Kefiran-carboxymethyl cellulose biocomposite films incorporated

104 EngO was highly active toward carboxymethyl cellulose but showed no activity towards x

105 te well with analysis of the same samples by carboxymethyl cellulose chromatography.

106 scale bonding of MXEne platelets with sodium carboxymethyl cellulose combined with covalent bridging

107 2, ethanol and (NH4)2SO4 precipitations, and carboxymethyl cellulose complexation.

108 Therefore, MP 1:9 incorporated with blended carboxymethyl cellulose film increased the water barrier

109 cid, fulvic acid, alginate, citric acid, and carboxymethyl cellulose greatly enhanced the stability a

110 The immobilized cellulase (tested by carboxymethyl cellulose hydrolysis at 1% concentration)

111 lanted with HT29 cells and fed with vehicle (carboxymethyl cellulose or phosphatidylcholine) or 200 m

112 The Dex-NW was fabricated using carboxymethyl cellulose polymer and contains arrays of 5

113 (BMCC), filter paper, swollen cellulose, and carboxymethyl cellulose were measured.

114 te, 5 wt % of acetylene black, and 3 wt % of carboxymethyl cellulose with an areal loading higher tha

115 dy shows that the mucoadhesive properties of carboxymethyl cellulose, a commonly used polysaccharide

116 low catalytic activity on swollen cellulose, carboxymethyl cellulose, bacterial microcrystalline cell

117 n appropriate electrode formulation based on carboxymethyl cellulose, carbon black, and vapor ground

118 A Fe(3+)-ion cross-linked carboxymethyl cellulose, Fe(3+)-CMC, redox-active gel ex

119 es which contain only beta-1,4 bonds such as carboxymethyl cellulose, microcrystalline cellulose, Wha

120 ound that inclusion of a viscosity enhancer, carboxymethyl cellulose, overcame this effect and retain

121 nt enhanced transport of Pd-NZVI coated with carboxymethyl cellulose, rhamnolipid biosurfactants, and

122 natural and nontoxic organic macromolecules (carboxymethyl cellulose, rhamnolipid biosurfactants, and

123 croparticles containing biodegradable sodium carboxymethyl cellulose, sodium alginate, and sodium hya

124 h Man5B in the hydrolysis of beta-mannan and carboxymethyl cellulose.

125 y active toward xylan, but not active toward carboxymethyl cellulose.

126 nding affinity for crystalline cellulose and carboxymethyl cellulose.

127 uar gum, gellan gum, xanthan gum, and sodium carboxymethyl cellulose.

128 t does not bind to xylan, galactomannan, and carboxymethyl cellulose.

129 nzymes were assayed for their activities on (carboxymethyl)cellulose, phosphoric acid-swollen cellulo

130 ,4-glucans in in vitro cellulase assays with carboxymethyl-cellulose as substrate.

131 Oxygen encapsulated nanosize carboxymethyl cellulosic nanobubbles were developed for

132 he dissociation constants of complexes with (carboxymethyl)chitin complexes, suggesting that ground s

133 D52A ChEWL- and GoEWL-catalyzed cleavage of (carboxymethyl)chitin may be partially fulfilled by an ap

134 y, complex nanoparticles were developed from carboxymethyl chitosan (CMCS) and soy protein isolate (S

135 In this study, zein and zein/carboxymethyl chitosan (CMCS) nanoparticles were prepare

136 ent cation salts CaCl(2), MnCl(2) as well as carboxymethyl chitosan (CMCS) on inhibition of acylation

137 NP) containing a poly(N-isopropylacrylamide)-carboxymethyl chitosan shell and poly lactic-co-glycolic

138 er and magnetite nanoparticles are joined by carboxymethyl chitosan, useful in biological environment

139 oxygen from O2 to form alpha-hydroxy- delta-carboxymethyl cis-muconic semialdehyde.

140 Of the incorporated carboxymethyl (CM) group, 1.1 per subunit, >90% was in C

141 yst-free synthesis of 6-hydroxy indoles from carboxymethyl cyclohexadienones and primary amines has b

142 The cyclohexane derivative cis-2-(carboxymethyl)cyclohexane-1-carboxylic acid [(1R,2R)-/(1

143 exane-1-carboxylic acid [(1R,2R)-/(1S,2S)-2-(carboxymethyl)cyclohexane-1-carboxylic acid] has previou

144 ntaining a longer peptide part modified with carboxymethyl-cytosine instead of adenosine was describe

145 Esters of 5-O-acetyl- or 5-azido-5-deoxy-3-(carboxymethyl)-D-ribofuranose were coupled with nucleoba

146 -deoxyguanosine (M(1)dG) adduct and the O(6)-carboxymethyl-deoxyguanosine (O(6)CMdG) adduct to demons

147 Occurrence of the Se-carboxymethyl derivative of radioactive selenocysteine i

148 ree thiols with iodoacetic acid, forming the carboxymethyl derivative of the cysteine residues, is pr

149 A carboxymethyl derivative of yeast beta-glucan enhanced t

150 (I)-O-, 3(I)-O-, and 6(I)-O-formylmethyl or -carboxymethyl derivatives.

151 In order to immobilize BSA, carboxymethyl dextran hydrogel (CMD) Au chip was used.

152 methods described in this paper) and in the carboxymethyl dextran matrix of commercially available s

153 gG as the detecting molecule, coupled onto a carboxymethyl dextran-coated gold crystal.

154 ific interactions of the HMG proteins with a carboxymethyl-dextran matrix, a novel method using a cho

155 oride) with either adenosine triphosphate or carboxymethyl-dextran using a microfluidic flow-focusing

156 chain onto the reducing end of CMD, forming carboxymethyl-dextran-block-poly(ethylene glycol) (CMD-b

157 A novel radioactive thiol reagent, 1-S-[3H]carboxymethyl-dithiothreitol (DTT-S-C[3H(2)]CO(2)H, [3H]

158 by reacting with azide-PEG(2k) succinimidyl carboxymethyl ester (NHS-PEG(2k)-N(3)) cross-linkers.

159 .e., primary amines) or electrophilic (i.e., carboxymethyl esters) functional groups have been covale

160 arboxyl, the first derivative (5) contains a carboxymethyl ether at the 6-position and a secondary am

161 The use of a masked carboxymethyl function off the lactam nitrogen provided

162 2,4,6-trimethylphenyl)-amino]-2-oxoethyl]-N-(carboxymethyl )-glycine ((99m)Tc-mebrofenin) and its ana

163 -one (CP-93,129), sumatriptan, serotonin-5-O-carboxymethyl-glycyl -tyrosinamide (GTI), 5-methylaminos

164 stable analogs that result from replacing a carboxymethyl group at the 4-position with a fluoroalkyl

165 eir modification with the negatively charged carboxymethyl group in monomeric Abeta also destabilized

166 modification with a farnesyl isoprenoid and carboxymethyl group is required for full biological acti

167 modification with a farnesyl isoprenoid and carboxymethyl group is required for full biological acti

168 enzyme activity that demethylates the C13(2)-carboxymethyl group present at the isocyclic ring of Chl

169 arget aspartyl-tRNA synthetase, and that the carboxymethyl group prevents resistance that can occur d

170 mass spectrometry, these FCCs had an intact carboxymethyl group, which slowed down their isomerizati

171 carboxy-SAM, which serves as a donor of the carboxymethyl group.

172 methylene groups from the macrocycle and the carboxymethyl groups occupy the rear and sides of the mo

173 n, N-(p-cyanophenyl)-N'-(diphenylmethyl)-N"-(carboxymethyl)guan idine (NC174), has been determined to

174 e that is selectively inserted opposite O(6)-carboxymethyl-guanine DNA by an engineered polymerase an

175 linear relationship with the amount of O(6)-carboxymethyl-guanine in the target sequence.

176 presence and location in the genome of O(6)-carboxymethyl-guanine.

177 The hydrogel was made of amphipathic carboxymethyl-hexanoyl chitosan (CHC), beta-glycerol pho

178 showed that inhibition of CBS activity by O-(Carboxymethyl) hydroxylamine hemihydrochloride (AOAA) si

179 oxy]octanoyl]-sn-glycero-3-N-[11- [N',N'-bis[carboxymethyl]imino]-3,6,9-trioxaundecanoyl] phosphatidy

180 The substrate analog N(2)-(carboxymethyl)-l-arginine (CMA) was adenylated by ATP in

181 ding, the truncated substrate analogue N(2)-(carboxymethyl)-L-arginine was synthesized and demonstrat

182 Target compound 5, the N tau-(carboxymethyl)-L-histidine derivative of 4, was also pre

183 inobutryic acid (GABA) and Nalpha,Nalpha-bis(carboxymethyl)-L-lysine (BCML) as competitive inhibitors

184 determination of free and total Nepsilon-(1-Carboxymethyl)-L-Lysine (CML) and free Nepsilon-(1-Carbo

185 ormation of Amadori products (AP), Nepsilon-(Carboxymethyl)-L-lysine (CML), Nepsilon-(Carboxyethyl)-L

186 using pyrenebutyric acid Nalpha',Nalpha-bis(carboxymethyl)-L-lysine amide (NTA-pyrene) and [tris-(2,

187 IL-COOH was further modified with N,N'-bis (carboxymethyl)-l-lysine hydrate to bind copper ions and

188 rotein glycation (formation of furosine, Ne-(carboxymethyl)-l-lysine, Ne-(carboxyethyl)-l-lysine, and

189 glycation (formation of furosine, Nepsilon-(carboxymethyl)-l-lysine, Nepsilon-(carboxyethyl)-l-lysin

190 f the Maillard reaction (furosine, Nepsilon-(carboxymethyl)-l-lysine, Nepsilon-(carboxyethyl)-l-lysin

191 ion domain of the A/PCP fragment activated S-carboxymethyl-L-cysteine (kcat/Km = 840 mM-1 min-1) at 1

192 One of these compounds, S-carboxymethyl-l-cysteine (SCMC), is currently used for t

193 covalently aminoacylated itself with [35S]S-carboxymethyl-L-cysteine.

194 lation product in the human lens, N(epsilon)-carboxymethyl-L-lysine (CML), has an EDTA-like structure

195 jor advanced glycation end product, Nepsilon-carboxymethyl-L-lysine, ruling out effects of cellular a

196 sphorylation with a nonnatural amino acid, p-carboxymethyl-l-phenylalanine (pCMF), we demonstrated th

197 hemically stable phosphotyrosine analogue (p-Carboxymethyl-L-phenylalanine, pCMF).

198 The higher aromatics are found to yield carboxymethyl lactones derived from the initially formed

199 elle-forming material, folic acid-conjugated carboxymethyl lauryl chitosan (FA-CLC), and superparamag

200 We hypothesized that carboxymethyl lipids such as (carboxymethyl)phosphatidyl

201 resentative glycation structures: N(epsilon)-carboxymethyl lysine (CM-OVA), N(epsilon)-carboxyethyl l

202 on end products (AGEs), including N(epsilon)-carboxymethyl lysine (CML), which have been implicated i

203 r weight, pentosidine content, and N-epsilon-carboxymethyl lysine content.

204 Carboxyethyl lysine, carboxymethyl lysine, and methylglyoxal hydroimidazolone

205 Carboxymethyl lysine, another oxidative modification, wa

206 fasting plasma glucose (FPG), serum N(euro)-(carboxymethyl) lysine (CML), and periodontal parameters

207 ed glycation end product in skin, N-epsilon-(carboxymethyl) lysine (CML)-collagen, could induce fibro

208 n had QW, as detected by an anti-N(epsilon)-(carboxymethyl)lysine (anti-CML) antibody.

209 h as diabetes and renal failure, N(epsilon)-(carboxymethyl)lysine (CML) adducts, are ligands of RAGE.

210 N()-(carboxymethyl)lysine (CML) AGE is one of the major biolo

211 ith regards to the inhibition of N(epsilon)-(carboxymethyl)lysine (CML) formation.

212 the main precursors of AGEs and N(epsilon)-(carboxymethyl)lysine (CML) found to be predominantly hig

213 Of all AGEs, Nepsilon-(carboxymethyl)lysine (CML) is a major glycoxidation prod

214 Nepsilon-(Carboxymethyl)lysine (CML) is a stable chemical modifica

215 Nepsilon-(Carboxymethyl)lysine (CML) is an advanced glycation end

216 on, reacts with proteins to form N(epsilon)-(carboxymethyl)lysine (CML), a chemically well-characteri

217 Furthermore, Nepsilon-(carboxymethyl)lysine (CML), a chemically well-characteri

218 uman serum albumin modified with N(epsilon)-(carboxymethyl)lysine (CML), a major AGE adduct that prog

219 t these effects were mediated by N(epsilon)-(carboxymethyl)lysine (CML), an important AGE found in vi

220 N(epsilon)-(carboxymethyl)lysine (CML), N(epsilon)-(1-carboxyethyl)l

221 Dietary, plasma and urinary AGEs N(euro)-(carboxymethyl)lysine (CML), N(euro)-(carboxyethyl)lysin

222 GO, GO, and 3-DG and protein-bound Nepsilon-(carboxymethyl)lysine (CML), Nepsilon-(1-carboxyethyl)lys

223 r the presence of the major AGEs N(epsilon)-(carboxymethyl)lysine (CML), VCAM-1, neutrophilic granulo

224 of a known RAGE protein ligand, N(epsilon)-(carboxymethyl)lysine (CML)-mouse serum albumin (MSA), on

225 of the immunoreactive AGE/ALE N( epsilon )-(carboxymethyl)lysine (CML).

226 Ga(III) or Fe(III) and N(alpha),N(alpha)-bis(carboxymethyl)lysine (LysNTA) in solution and electrospr

227 emistry and Western analysis for N(epsilon)-(carboxymethyl)lysine [CML]) was assessed.

228 n and lipoxidation end products, N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine

229 Like the N-carboxy-alkyllysines Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine,

230 lfoxide are formed in concert with Nepsilon-(carboxymethyl)lysine and pentosidine during glycoxidatio

231 The glycoxidation products Nepsilon-(carboxymethyl)lysine and pentosidine increase in skin co

232 two most commonly measured AGEs, N(epsilon)-(carboxymethyl)lysine and pentosidine, are glycoxidation

233 ased in diabetes, in contrast to N(epsilon)-(carboxymethyl)lysine and pentosidine.

234 hibited formation of the AGE/ALE N(epsilon)-(carboxymethyl)lysine during reaction of GO and GLA with

235 nidine inhibited glucose-induced N(epsilon)-(carboxymethyl)lysine formation on beta2M.

236 ein cross-linking and formation of Nepsilon-(carboxymethyl)lysine, an AGE product.

237 acilitated increased formation of AGEs (N-E-(carboxymethyl)lysine, methylglyoxal- and glyoxal-derived

238 advanced glycation endproducts (N(epsilon)-(carboxymethyl)lysine, N(epsilon)-(carboxyethyl)-lysine,

239 lipoxidation end products (ALEs) N(epsilon)-(carboxymethyl)lysine, N(epsilon)-(carboxyethyl)lysine, m

240 dy, plasma levels of protein-bound Nepsilon-(carboxymethyl)lysine, Nepsilon-(carboxyethyl)lysine, and

241 and two subclasses of AGE, i.e., N(epsilon)-(carboxymethyl)-lysine (CML) and pentosidine (PENT).

242 agnostic serum concentrations of sRAGE or N-(carboxymethyl)-lysine (CML)-AGE and hepatocellular carci

243 ons of prediagnostic measures of N(epsilon)-(carboxymethyl)-lysine (CML)-AGE and sRAGE with pancreati

244 etical RyR2 peptides with single N(epsilon)-(carboxymethyl)-lysine, imidazolone A, imidazone B, pyrra

245 vels were determined by ELISA for N(epsilon)-carboxymethyl-lysine (CML) and methylglyoxal-derivatives

246 ease of LDH and lower glycoxidation products carboxymethyl-lysine (CML) and pentosidine, improved fun

247 d with serum concentrations of the major AGE carboxymethyl-lysine (CML) and the soluble receptor for

248 o far been thought to have a high N(epsilon)-carboxymethyl-lysine (CML) content.

249 N(epsilon)-carboxymethyl-lysine (CML) is measured in food, but ther

250 e immunity, while increased serum N(epsilon)-carboxymethyl-lysine (CML), an advanced glycation end pr

251 In 2515 participants, intake of 3 dAGEs [carboxymethyl-lysine (CML), N-(5-hydro-5-methyl-4-imidaz

252 d skin samples were monitored for N(epsilon)-carboxymethyl-lysine and methylglyoxal derivatives by en

253 coccus aureus biofilm formation and Nepsilon-carboxymethyl-lysine generation ability under food heat

254 Nepsilon-carboxymethyl-lysine level in S. aureus biofilm possesse

255 Besides, free and bound Nepsilon-carboxymethyl-lysine level in weak, moderate and strong

256 Neither carboxymethyl-lysine nor glyoxal hydroimidazolone, two m

257 ard reaction markers (hydroxymethylfurfural, carboxymethyl-lysine, absorbance at 420nm and total fluo

258 mocitrulline accumulates more intensely than carboxymethyl-lysine, one of the major advanced glycatio

259 This derivative, N,N-bis[carboxymethyl]lysine (BCML), was easily coupled to a mal

260 gressive increase in RAGE ligands (S100B, N-[carboxymethyl]lysine, HSP70, and HMGB1).

261 , glycoxidation (pentosidine and N(epsilon)-[carboxymethyl]-lysine [CML]), and crosslinking (acid and

262 ogs, the migrastatin core ether (ME) and the carboxymethyl-ME (CME), which exhibit high efficacy in b

263 vestigated using NO photolyzed from N,N'-bis(carboxymethyl)-N,N'-dinitroso-p-phenylenediamine using a

264 To this end, the N1-carboxymethyl-NAD+ species were covalently attached to p

265 Carboxymethyl-ornithine and furornithine increased with

266 The proteins were assayed for carboxymethyl-ornithine and glycated ornithine ("furorni

267 R agonists E-6-BSA-FITC [beta-estradiol-6-(O-carboxymethyl)oxime-bovine serum albumin conjugated with

268 Various amide derivatives of 8-[4-[[carboxymethyl]oxy]phenyl]-1,3-di-(n-propyl)xanthine, 4a,

269 usly shown to recognize CML, suggesting that carboxymethyl-PE may be a component of AGE lipids detect

270 as (carboxymethyl)phosphatidylethanolamine (carboxymethyl-PE) would also be formed in these reaction

271 render larger rotational flexibility of the carboxymethyl pharmacophore.

272 and NODA-MPAA is 2-[4-(carboxymethyl)-7-{[4-(carboxymethyl)phenyl]methyl}-1,4,7-triazacyclononan-1 -y

273 n inhibitor containing the singly charged p-(carboxymethyl)phenylalanine residue (cmF) as a phosphoty

274 information presented here suggests that the carboxymethyl-phenylalanine residue may be a viable Tyr(

275 othesized that carboxymethyl lipids such as (carboxymethyl)phosphatidylethanolamine (carboxymethyl-PE

276 la-Val-Gly-His-Sta-Leu-NH(2) (Pip, 4-amino-1-carboxymethyl-piperidine), was conjugated to 1,4,7-triaz

277 ]-BN(6-14)NH2 (DOTA-AR), and DOTA-(4-amino-1-carboxymethyl-piperidine)-[D-Phe(6), Sta(13)]-BN(6-14)NH

278 (68)Ga-labeled DOTA-4-amino-1-carboxymethyl-piperidine-d-Phe-Gln-Trp-Ala-Val-Gly-His-S

279 (68)Ga-labeled DOTA-4-amino-1-carboxymethyl-piperidine-D-Phe-Gln-Trp-Ala-Val-Gly-His-S

280 irst substrate to bind followed by (2S,5S)-5-carboxymethyl proline and PPi is the last product releas

281 -carbapenam-3-carboxylic acid from (2S,5S)-5-carboxymethyl proline based on characterization of the p

282 proposed a role for each moiety of (2S,5S)-5-carboxymethyl proline for binding to the active site of

283 -carbapenam-3-carboxylic acid from (2S,5S)-5-carboxymethyl proline.

284 The substituted-5-carboxymethyl-prolines were converted into the correspon

285 ursors in syntheses of the neuroexcitants 3-(carboxymethyl)pyrrolidine-2,4-dicarboxylic acid 43, alph

286 Cross-linked carboxymethyl rice starches (CL-CMRSs) were prepared fro

287 the novel tyrosine phosphate bioisostere, O-carboxymethyl salicylic acid; demonstration that the tyr

288 y Edman degradation identified residue 16 as carboxymethyl selenocysteine, which corresponded to the

289 iodoacetate or 3-bromopropionate yielded Se-carboxymethyl-selenocysteine or Se-carboxyethyl-selenocy

290 by recurrent mutations, and through loss of carboxymethyl-sensitive heterotrimeric complexes.

291 te matter by a series of chromatographies on carboxymethyl-Sephadex and silica gel in chloroform and

292 tion of N-(glucitol)ethanolamine (GE) and N-(carboxymethyl)serine (CMS), two products of nonenzymatic

293 e Mukaiyama hydration that orients a pendant carboxymethyl side chain cis to the bulky octahydronapth

294 1-O-Alkyl-2-carboxymethyl-sn-glycero-3-phosphocholine (Edelfosine) l

295 For the subsequent migration of the carboxymethyl substituent, two possible directions were

296 The degree of carboxymethyl substitution was between 0.24 and 0.28, wh

297 plex coacervates obtained from gelatin A and carboxymethyl tara gum (CMTG) were used as wall material

298 nosine-L-methionine (Cx-SAM) and catalyzes a carboxymethyl transfer reaction resulting in formation o

299 decylphosphonium bromide (1P14CONH(2)Br) and carboxymethyl-tri-n-tetradecylphosphonium bromide (1P14C

300 amine, generated through the condensation of carboxymethyl unit of the substrates with an external am