ライフサイエンスコーパス: cardiolipin

1 phosphoinositides or sulfatide, but not with cardiolipin.

2 of the DPPC acyl chain response from that of cardiolipin.

3 iae develop lung injury with accumulation of cardiolipin.

4 t of the mitochondrial membrane phospholipid cardiolipin.

5 of the mitochondrial-specific phospholipid, cardiolipin.

6 on anionic phospholipids and in particular, cardiolipin.

7 e for the mitochondria-specific phospholipid cardiolipin.

8 ment on the interaction of cytochrome c with cardiolipin.

9 een defined as phosphatidylglycerol (PG) and cardiolipin.

10 cts directly with membrane lipids, including cardiolipin.

11 mitochondrial ADP/ATP carrier, does not bind cardiolipin.

12 eurodegenerative disorders are inactive with cardiolipin.

13 ic molecular form of the mitochondrial lipid cardiolipin.

14 alf as many as observed on membranes without cardiolipin.

15 only partially dependent on the presence of cardiolipin.

16 tafazzin is the mitochondria-specific lipid cardiolipin.

17 uffer a structural transformation induced by cardiolipin.

18 on EMRE and also on the mitochondrial lipid cardiolipin.

19 ble for the interaction of this protein with cardiolipin.

20 RP1 can also bind phosphatidic acid (PA) and cardiolipin.

21 allowed the identification of brain-specific cardiolipins.

22 ncharacterized adducts, including ammoniated cardiolipins.

23 Cardiolipin (70:5) emerged as a potential point-of-care

24 using perhexiline resulted in a depletion of cardiolipin, a key component of mitochondrial membranes,

25 These findings support links among cardiolipin abnormalities, respiratory supercomplex inst

26 The osmolyte trehalose and membrane lipid cardiolipin accumulate in E. coli cells cultivated at hi

27 Brain-specific cardiolipins accumulate in plasma early after return of

28 als tested for lupus anticoagulant(LA), anti-cardiolipin (aCL), and anti-beta2-glycoprotein1(aGP1).

29 ding, where the unfolded form interacts with cardiolipin acyl chains within the bilayer to induce per

30 levels of sphingomyelin and lower levels of cardiolipin, among other phospholipids in the apical pla

31 the "wall-less" oxidation reactions of 18:1 cardiolipin and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosph

32 erfering with the mitochondrial phospholipid cardiolipin and causing inefficient electron transfer re

33 2), which also binds the mitochondrial lipid cardiolipin and functions in the assembly of respiratory

34 ant microdomains via direct interaction with cardiolipin and inhibits MAVS protein-mediated apoptosis

35 Lateral segregation of cardiolipin and membrane hemifusion would be critical fo

36 The non-bilayer-forming phospholipids cardiolipin and phosphatidylethanolamine are required fo

37 er reports that the abundances of endogenous cardiolipin and phosphatidylethanolamine halve during el

38 n vivo, oxidize the 2'-OH glycerol moiety on cardiolipin and phosphatidylglycerol to produce diacylgl

39 the interaction of 3',6-dinonyl neamine with cardiolipin and phosphatidylglycerol, two negatively cha

40 inds acidic phospholipids in vitro, notably, cardiolipin and phosphatidylserine, and interacts with l

41 For both cardiolipin and POPG, every unsaturated oleyl chain is o

42 f mitochondrion-targeted agents that deplete cardiolipin and promote cancer cell death.

43 sis, leading to increased bacterial membrane cardiolipin and reduced phosphatidylglycerol.

44 mitochondrial-targeted peptide that binds to cardiolipin and stabilizes mitochondrial function.

45 tafazzin cause abnormal molecular species of cardiolipin and the clinical phenotype of Barth syndrome

46 hment with typical mitochondrial lipids like cardiolipins and demonstrated the presence of several ub

47 igand cBID, the mitochondrion-specific lipid cardiolipin, and membrane geometrical curvature) all pro

48 ratory complexes and the mitochondrial lipid cardiolipin, and Mic60/Mic19, which assembles independen

49 onic (phosphatidylserine, phosphatidic acid, cardiolipin, and phosphatidylinositol 4,5-bisphosphate (

50 n binding domain changes its ability to bind cardiolipin, and tumor cells expressing this mutant have

51 phosphates on polar phospholipids, like for cardiolipins, and are necessary for salmonella OM integr

52 elease OMVs that contain phospholipids, like cardiolipins, and components of LPS molecules, like lipi

53 such as ceramides, glycerophosphoglycerols, cardiolipins, and glycerophosphocholines.

54 increased levels of lipid A-core molecules, cardiolipins, and phosphatidylethanolamines and decrease

55 Labile compounds such as gangliosides and cardiolipins are detected in the negative ion mode direc

56 Since brain cardiolipins are not present in plasma normally, we hypo

57 counterparts where cone-shaped lipids, like cardiolipin, are involved.

58 With the addition of the lipid cardiolipin, assembly of these proteins into nanodiscs w

59 reactive oxygen species by removing damaged cardiolipin before it induces apoptosis.

60 The SS-31-interacting proteins, all known cardiolipin binders, fall into two groups, those involve

61 Alteration to maspin's cardiolipin binding domain changes its ability to bind c

62 ended lipid anchorage model for cytochrome c/cardiolipin binding.

63 These phenotypes were mediated by enhanced cardiolipin biosynthesis, leading to increased bacterial

64 erestingly, among yeast mutants deficient in cardiolipin biosynthesis, only the crd1-null mutant, whi

65 cally, inhibition of TAZ decreased levels of cardiolipin but also altered global levels of intracellu

66 omparable efficiency to generate triacylated cardiolipin by acyltransferase/acyl-acyl carrier protein

67 nd that tafazzin catalyzes the remodeling of cardiolipin by combinations of forward and reverse trans

68 The resulting oxygenation of cardiolipin by cytochrome c provides an early signal for

69 o-damage-associated molecular pattern (DAMP) cardiolipin can be detected in the lungs.

70 s Tim23 membrane attachment, suggesting that cardiolipin can influence preprotein import.

71 tion involving its interaction with membrane cardiolipin (CDL), its peroxidase activity, and the init

72 e, ganglioside GM3, GM2, GM1, GD3 and GD1a), cardiolipin, cholesterol and cholesteryl esters are elev

73 dering along with decreased intensity of the cardiolipin cis-double-bond stretching modes.

74 Cardiolipin (CL) analysis demands high specificity, due

75 IMS in imaging high-mass signals from intact cardiolipin (CL) and gangliosides in normal brain and th

76 Of these, cardiolipin (CL) and phosphatidylethanolamine (PE) parti

77 ecules including phospholipids, particularly cardiolipin (CL) and phosphatidylethanolamine (PE).

78 A binds tightly to the anionic phospholipids cardiolipin (CL) and phosphatidylglycerol (PG).

79 choline (PC), phosphatidylethanolamine (PE), cardiolipin (CL) and sphingomyelin contents were higher

80 spholipids phosphatidylethanolamine (PE) and cardiolipin (CL) are required for the biogenesis of beta

81 ylation and as a peroxidase that reacts with cardiolipin (CL) during apoptosis.

82 noanionic phosphatidylglycerol and dianionic cardiolipin (CL) in this essential membrane-related proc

83 Cardiolipin (CL) is a dimeric phospholipid with critical

84 Cardiolipin (CL) is a key phospholipid in mitochondrial

85 Cardiolipin (CL) is a mitochondrial phospholipid with a

86 Cardiolipin (CL) is an anionic phospholipid with a chara

87 Cardiolipin (CL) is an atypical, dimeric phospholipid es

88 The unique tetra-acyl phospholipid cardiolipin (CL) is located in the inner mitochondrial m

89 Cardiolipin (CL) is the signature phospholipid of mitoch

90 Cardiolipin (CL) is the signature phospholipid of mitoch

91 In recent years, cardiolipin (CL) oxidation products were recognized as p

92 that the prokaryotic-enriched anionic lipid Cardiolipin (CL) plays a key-role in the TFDs delivery t

93 Cardiolipin (CL) plays an important role in OM biogenesi

94 described in humans with genetic defects in cardiolipin (CL) synthesis (Barth syndrome).

95 Cardiolipin (CL) that is synthesized de novo is deacylat

96 1-palmitoyl 2-oleoyl-diphosphatidylglycerol/cardiolipin (CL) to mimic the lipid composition of the b

97 Cardiolipin (CL), a membrane phospholipid in bacteria an

98 palmitate levels and increases the levels of cardiolipin (CL), a mitochondrial inner membrane-specifi

99 For example, the loss of cardiolipin (CL), a signature non-bilayer-forming phosph

100 Mitochondria contain cardiolipin (CL), an organelle-specific phospholipid tha

101 s a peroxidase activated by interaction with cardiolipin (CL), and resulting in selective CL peroxida

102 mitochondrial signature glycerophospholipid, cardiolipin (CL), binds to transporters of the inner mit

103 f oxidized mitochondrial phospholipids, e.g. cardiolipin (CL), by excising oxidized polyunsaturated f

104 d from a mitochondria-specific phospholipid, cardiolipin (CL), is oxidized by the intermembrane-space

105 with the mitochondrion-specific phospholipid cardiolipin (CL), leading to a gain of peroxidase activi

106 DHA extensively remodeled the acyl chains of cardiolipin (CL), mono-lyso CL, phosphatidylcholine, and

107 Defective cardiolipin (CL), phosphatidylethanolamine, and phosphat

108 Cardiolipin (CL), the signature phospholipid of mitochon

109 Cardiolipin (CL), the signature phospholipid of mitochon

110 les and septa of Escherichia coli cells in a cardiolipin (CL)-dependent manner.

111 Lysocardiolipin acyltransferase (LYCAT), a cardiolipin (CL)-remodeling enzyme, is crucial for maint

112 hey are enriched in the anionic phospholipid cardiolipin (CL).

113 ms are dependent on the mitochondrial lipid, cardiolipin (CL).

114 s close to the conserved binding location of cardiolipin (CL).

115 ical modification of the mitochondrial lipid cardiolipin (CL).

116 hatidylethanolamine, phosphatidylcholine, or cardiolipin (CL).

117 ipids with greater activity upon addition of cardiolipin (CL).

118 in glycerophospholipid metabolism [including cardiolipin (CL)], lipogenesis, and gluconeogenesis.

119 Cardiolipins (CL) represent unique phospholipids of bact

120 haracterization are expanded for analysis of cardiolipins (CL), a class of phospholipids that exhibit

121 selected for transmission of doubly charged cardiolipins (CL), for example, detection of 71 differen

122 lly high abundance and chemical diversity of cardiolipins (CL), including many oxidized species.

123 Observations are consistent with variants of cardiolipins (CL), phosphatidylglycerols (PG), phosphati

124 vo We propose that binding of sphingosine to cardiolipin clusters cardiolipin molecules in the plasma

125 n phosphatidylethanolamines and depletion in cardiolipins compared to the bulk membrane lipid.

126 r receptor kinase 1/2 activation; normalized cardiolipin composition in mitochondria; reduced circula

127 signaling events, raise questions about how cardiolipin concentration affects mitochondrial membrane

128 much-needed insights to help understand how cardiolipin concentration modulates the biophysical prop

129 We found that changes to cardiolipin concentration only resulted in minor changes

130 S Typhimurium bacteria increase their OM cardiolipin concentrations during activation of the PhoP

131 In this study, we compare the case of cardiolipin-containing giant unilamellar vesicles with t

132 id micro-injection near the external side of cardiolipin-containing giant unilamellar vesicles, leads

133 at cytochrome c can induce pore formation in cardiolipin-containing phospholipid membranes, leading t

134 s work, the interaction of cytochrome c with cardiolipin-containing phospholipid vesicles, serving as

135 For binding to the convex outer surface of cardiolipin-containing vesicles, a two-step structural r

136 On the concave inner surface of cardiolipin-containing vesicles, the structural transiti

137 rome-correlated leakage was observed only in cardiolipin-containing vesicles.

138 Here we report binding to concave, cardiolipin-containing, membrane surfaces and compare fi

139 preserved mitochondrial structure including cardiolipin content after reperfusion compared with IR o

140 with cBID in a manner adjustable by membrane cardiolipin content and curvature degree.

141 However, differences in cardiolipin content between the two mitochondrial membra

142 We postulate that the reduced cardiolipin content in ftsh4 mitochondria leads to pertu

143 embranes, as well as dynamic fluctuations in cardiolipin content in response to stimuli and cellular

144 ver, markers of mitochondrial biogenesis and cardiolipin content were strongly reduced only in males.

145 an intact mitochondrial structure including cardiolipin content, preserved activity of the electron

146 rest, a significant reduction in hippocampal cardiolipins corresponded to their release from the brai

147 that bind to negatively charged lipids like cardiolipin could be promising antibacterial compounds.

148 tidylglycerol, or the tetra-acylated form of cardiolipin could not serve as a competitive inhibitor i

149 ted protein, providing the first view of the cardiolipin/cytochrome c interaction interface at atomic

150 ion of respiration was neither diminished by cardiolipin deficiency nor conferred by trehalose overpr

151 x that may bridge the envelope for regulated cardiolipin delivery.

152 ular dynamics simulations to investigate the cardiolipin-dependent properties of ternary lipid bilaye

153 Cardiolipin depletion-induced changes in the Trypanosoma

154 These two distinct cardiolipin derivatives were both translocated with comp

155 ers and negative intrinsic curvature lipids (cardiolipin, diacylglycerol) facilitating fusion.

156 eter and selected curvature-inducing lipids (cardiolipin, diacylglycerol, and lyso-phosphatidylcholin

157 we used a liposome model to demonstrate that cardiolipin directly inhibits membrane permeabilization

158 model of apoptosis in which maspin binds to cardiolipin, displaces cytochrome c from the membrane, a

159 ned changes in the acyl chain composition of cardiolipin do not alter either mitochondrial morphology

160 parameters, we followed the accumulation of cardiolipin during the reaction from the initial state t

161 xamined the interaction of cytochrome c with cardiolipin embedded in a variety of model phospholipid

162 Cardiolipin enhances Tim23 membrane attachment, suggesti

163 (apparent K(d) of ~1.31 muM) for binding to cardiolipin-enriched membranes.

164 IRF-1 targeting to mDRM possibly by inducing cardiolipin exposure on the outer membrane of mitochondr

165 elongation, cyclopropanation, and increased cardiolipin formation.

166 -terminal domain binds phosphoinositides and cardiolipin, forms membrane-disrupting pores, and execut

167 Cardiolipin, free fatty acids, and branched lipids can a

168 thesis that the mitochondrion-specific lipid cardiolipin functions as a first contact site for Bax du

169 Depletion of cardiolipin further affects the stability of the TIM23 c

170 Tightly bound lipids (including cardiolipins) further stabilize interactions between the

171 ontaining transmembrane protein, which binds cardiolipin glycerophospholipids near the inner membrane

172 n between cytochrome c and the anionic lipid cardiolipin has been proposed as a primary event in the

173 arities between different molecular forms of cardiolipin have never been established.

174 leaflet, that is promoted by protonation of cardiolipin headgroups.

175 We also found a novel cardiolipin hydrolysis reaction by phospholipase A2 to f

176 rebral score was derived from brain-specific cardiolipins identified in plasma of patients with varyi

177 significantly correlated with elevated anti-Cardiolipin IgA (sdCOVID and scCOVID, p-value<0.001), an

178 A (sdCOVID and scCOVID, p-value<0.001), anti-Cardiolipin IgM (sdCOVID, P=0.003; scCOVID, P<0.001), an

179 AqpZ is also stabilized by many lipids, with cardiolipin imparting the most significant resistance to

180 a foundational understanding of the role of cardiolipin in altering the properties in ternary lipid

181 binds to the highly negatively-charged lipid cardiolipin in bacterial plasma membranes.

182 Depletion of cardiolipin in cells significantly prevents maspin bindi

183 phospholipids, the biophysical properties of cardiolipin in higher number lipid mixtures are still no

184 Maspin binds to cardiolipin in mitochondria and triggers apoptosis.

185 acquire peroxidase activity when it binds to cardiolipin in mitochondrial membranes.

186 ing are consistent with functional roles for cardiolipin in stabilizing and lubricating the rotor, an

187 have indicated that an increased content of cardiolipin in the bacterial membrane may contribute to

188 ot significantly disturbed by the binding of cardiolipin in the context of the reverse micelle.

189 correlated tightly with the concentration of cardiolipin in the equilibrium state (lipid-dependent pa

190 31 primarily interacts with the phospholipid cardiolipin in the inner mitochondrial membrane.

191 rom the cytosol to mitochondria and binds to cardiolipin in the inner mitochondrial membrane.

192 y of cyt c gained upon its complexation with cardiolipin in the presence of reactive oxygen species.

193 ndance of the mitochondrial-specific lipids, cardiolipins, in normoxic conditions.

194 similar way, which can also be prevented by cardiolipin, indicating that they interact like transpor

195 Cardiolipin induces PPARgamma SUMOylation, which causes

196 Cardiolipin inhibits resolution of inflammation by suppr

197 transacylase that remodels the mitochondrial cardiolipin into its mature form.

198 Incorporation of cardiolipin into the reverse micelle surfactant shell ca

199 n and/or remodeling of lipids, in particular cardiolipin, into complex IV and.

200 tracts in negative ion mode can give rise to cardiolipins ionized as both singly and doubly deprotona

201 Cardiolipin is a mitochondrial lipid overexpressed in ma

202 Cardiolipin is a phospholipid of the inner mitochondrial

203 We show that the mitochondria-specific lipid cardiolipin is a potent stimulator of Drp1 GTPase activi

204 When cardiolipin is added at molar fractions of 10 or 20% to

205 Cardiolipin is an anionic lipid found in the mitochondri

206 The anionic lipid cardiolipin is an essential component of active ATP synt

207 s drastically reduced and the composition of cardiolipin is modified like in mutants lacking tafazzin

208 mitochondrial ADP/ATP carrier (yAAC3) toward cardiolipins is preserved in DPC, thereby suggesting tha

209 Overexpression of wild-type SIRT3 increased cardiolipin levels and rescued mitochondrial respiration

210 Measurements of renal cardiolipin levels, citrate synthase activity, rotenone-

211 E. coli ClsB significantly increased PG and cardiolipin levels, with the growth deficiency of pgsA n

212 on studies confirm that MgtA is found in the cardiolipin lipid domains in the membrane.

213 branes but also phosphatidylethanolamine and cardiolipin, lipids with high spontaneous negative curva

214 ate that the mitochondrial failure rescue by cardiolipin manipulation may be a new intriguing target

215 pathy biochemically characterized by reduced cardiolipin mass and increased monolysocardiolipin level

216 r role in activation of MgtA suggesting that cardiolipin may act as a Mg(2+) chaperone for MgtA.

217 ndings suggest a possible mechanism by which cardiolipin may mediate resistance to daptomycin, and th

218 lycero-3-phosphocholine (DPPC) or mixed-DPPC/cardiolipin membrane and containing a membrane-impermeab

219 mulated EHEC, wild-type GrlA associates with cardiolipin membrane domains via a patch of basic C-term

220 deletion of liaR altered the localization of cardiolipin microdomains in the cell membrane.

221 Brain polyunsaturated cardiolipins, mitochondria-unique and functionally essen

222 rall imbalance with most prominent effect on cardiolipin molecular sub-species.

223 wedge are filled by three specifically bound cardiolipin molecules and two other phospholipids.

224 ith c10- and c11-rings, the density of bound cardiolipin molecules at this site increased, but reside

225 terial c10- or c11-rings, the head-groups of cardiolipin molecules became associated selectively with

226 Hence, cardiolipin molecules in different organisms, and even d

227 nding of sphingosine to cardiolipin clusters cardiolipin molecules in the plasma membrane of bacteria

228 Evidence suggests that cardiolipin molecules segregate into such microdomains,

229 However, the residence times of cardiolipin molecules with the ring were brief and suffi

230 s, of the mitochondrial structural component cardiolipin, of the mitochondrial DNA content, and of th

231 Cytochrome c binds cardiolipin on the concave surface of the inner mitochon

232 586), but the biological role of increasing cardiolipins on the surface is not understood.

233 rthermore, phosphomimetic Cytc had decreased cardiolipin peroxidase activity and is more stable in th

234 o-apoptotic conditions, however, cyt c gains cardiolipin peroxidase activity, translocates into the c

235 ons including ROS production and scavenging, cardiolipin peroxidation, and mitochondrial protein impo

236 fied two subnetworks 'triacylglycerols' and 'cardiolipins-phosphatidylethanolamines (CL-PE)' characte

237 nstrated alterations in triacylglycerols and cardiolipins-phosphatidylethanolamines that precede the

238 a unique assemblage of features, including: cardiolipin, phosphonolipid, amino acid, and fatty acid

239 The head group of cardiolipin plays major role in activation of MgtA sugge

240 We also found that cardiolipin position along the bilayer surfaces correlat

241 cted to the cell membrane inner leaflet) and cardiolipin (present in the inner and outer leaflets of

242 gned tetramers in opposite leaflets and that cardiolipin prevents the translocation of tetramers to t

243 drial respiration and enzyme activities, and cardiolipin profile with no change in mitochondrial cont

244 ction by phospholipase A2 to form diacylated cardiolipin progressing to the completely deacylated hea

245 We observe that cardiolipin promotes the formation of periodic protein-f

246 regions that in many cases, are proximal to cardiolipin-protein interacting regions.

247 eta secretion, suggesting that mitochondrial cardiolipin release may trigger abacavir-induced inflamm

248 own (Taz(KD) ) mice, which exhibit defective cardiolipin remodeling and respiratory supercomplex inst

249 thetase, demonstrating the first evidence of cardiolipin remodeling in bacteria.

250 f the lipidomics signature revealed abnormal cardiolipin remodeling in diabetic kidneys, a cardinal s

251 Importantly, preventing cardiolipin remodeling initiation in yeast lacking TAZ1,

252 the renal mitochondrial fatty acid profile, cardiolipin remodeling, and citric acid cycle intermedia

253 s required for fatty acid beta-oxidation and cardiolipin remodeling, essential for functional mitocho

254 enhances mitochondrial respiration, induces cardiolipin remodeling, reduces specific sphingolipids,

255 al superoxide levels, possibly by regulating cardiolipin remodeling.

256 ing a phospholipid transacylase required for cardiolipin remodeling.

257 t, disrupted cristae structure and defective cardiolipin remodeling.

258 h selective interaction of cytochrome c with cardiolipin, resulting in protein unfolding, where the u

259 Cardiolipin reverses destabilizing effects of ADP and bo

260 veal a process by which COQ9 associates with cardiolipin-rich membranes and warps the membrane surfac

261 Although cardiolipin's structural and dynamic roles have been ext

262 cid, the most common fatty acid component of cardiolipin, show that C11 of linoleic acid can sit adja

263 affected by cytochrome c accumulation, while cardiolipin showed major changes in acyl chain structure

264 aphy/mass spectrometry method and determined cardiolipins speciation in human brain, heart, and plasm

265 Finally, pharmacological cardiolipin stabilization reverted the energetic impairm

266 g the associated detergent micelle size, but cardiolipin stabilizes by direct interactions as well.

267 Cardiolipin stabilizes UCP1, as demonstrated by reconsti

268 amine the subcellular distribution of CL and CARDIOLIPIN SYNTHASE (CLS) and analyzed loss-of-function

269 Instead, depletion of cardiolipin synthase 1 abolished abacavir-induced IL-1be

270 t E. coli or P. aeruginosa strains that lack cardiolipin synthase are resistant to sphingosine, both

271 is catalyzed by ClsB, a phospholipase D-type cardiolipin synthase.

272 ospholipid biosynthesis gene, cls2, encoding cardiolipin synthase.

273 dic acid from the ER to the mitochondria for cardiolipin synthesis.

274 (glucosylceramide) and glycerophospholipid (cardiolipin) synthesis.

275 t the levels of phosphatidylethanolamine and cardiolipin, the two key inner membrane phospholipids.

276 selective interactions of cytochrome c with cardiolipin, these experiments were repeated where the D

277 leoyl cardiolipin (TOCL)- and tetralinoleoyl cardiolipin (TLCL)-containing liposomes to evaluate the

278 itochondrial cristae, we estimate the LPR of cardiolipin to cytochrome c is between 50 and 100.

279 nner mitochondrial membrane via affinity for cardiolipin to promote respiratory chain function.

280 tions to investigate the specific binding of cardiolipins to yAAC3.

281 ydrated phospholipids, including tetraoleoyl cardiolipin (TOCL) and several phosphatidylcholine lipid

282 h in the presence and absence of tetraoleoyl cardiolipin (TOCL)- and tetralinoleoyl cardiolipin (TLCL

283 for pathogenesis, suggesting that increased cardiolipin trafficking to the OM is necessary for Salmo

284 In addition, the level of tafazzin, a cardiolipin transacylase, is drastically reduced and the

285 to previous claims that PbgA functions as a cardiolipin transporter(6-9), our structural analyses an

286 Here, SIRT5 was observed to bind to cardiolipin via an amphipathic helix on its N terminus.

287 s lost when the mitochondrial specific lipid cardiolipin was present, as Drp1 directly interacted wit

288 ver, the mitochondria-specific phospholipid, cardiolipin, was significantly reduced in both strains c

289 Increased levels of cardiolipin were associated with tubular mitochondria an

290 Nine of 26 brain-specific cardiolipins were detected in plasma and correlated with

291 Using a rat model of cardiac arrest, cardiolipins were quantified in plasma, brain, and heart

292 to the lipoidal antigen used in RPR testing (cardiolipin) were not detected in the MBA.

293 s, such as reactive oxygen species, DNA, and cardiolipin, which can cause NLRP3 inflammasome activati

294 lipids including glycosylated ceramides and cardiolipins, which have no direct connection to ether l

295 cation of 37 associated lipids, including 25 cardiolipins, which provides insight into protein-lipid

296 assay revealed that recombinant maspin binds cardiolipin with an apparent K(d),of ~15.8 muM and compe

297 HSD10 exhibits a strong preference for cardiolipin with oxidized fatty acids.

298 Drosophila Sniffer and human HSD10, oxidize cardiolipin with similar kinetic parameters.

299 pholipids to monolysocardiolipin to generate cardiolipin with unsaturated fatty acids.

300 y TLC reveal that UCP1 retains tightly bound cardiolipin, with a lipid phosphorus content equating to