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3 tive agent-it will be essential to depend on careful analysis of safety in humans as immune intervent
4 istal mutations can be a priori predicted by careful analysis of the conformational ensemble of the T
6 itial characterisation of bone tumours, with careful analysis of their matrix mineralisation, locatio
8 Patients with TAO in the course of HT need a careful and continued interdisciplinary approach both op
9 These results emphasize the importance of careful and critical analysis during interpretation of c
13 ed for years, and treatment regimens require careful and regular adjustments to avoid undertreatment
21 ent in current scHi-C protocols necessitates careful assessment of data quality before biological con
22 xceeding 60 min or 3 attempts should trigger careful assessment of futility and risks of continuing t
27 e-specific characteristics and management, a careful assessment of the regional climate is needed to
29 nverse odds of sampling weights, which under careful assumptions can transport effect estimates from
30 isting methods for sensitivity analyses with careful assumptions; systematic assessments of whether a
33 As illustrated by concrete example cases, careful attention to analysis details is needed in order
34 f glycemic control, medication regimens, and careful attention to comorbid conditions can help mitiga
37 lized by all high-risk groups, there must be careful attention to ensuring equitable access to this l
38 the mammalian radiation, which suggests that careful attention to interspecies divergence is needed w
40 ocol requires skills for culturing hPSCs and careful attention to morphological changes indicative of
42 rs can require algorithmic optimizations and careful attention to Spark's configuration parameters.
43 idemiology in coming years, although we need careful attention to the appropriate uses of prediction
45 selection of species for study; 2) use (with careful attention to welfare) animals that minimize the
48 upported by complex redox mixtures require a careful balance between kinetic limitations and spectral
49 arge-scale neural activity imaging entails a careful balance between recording fidelity and perturbat
51 fast reconstructions with real data require careful calibration, adequate data redundancy from a 2D
53 the study of rare variants, often chosen by careful candidate assessment, and 2) the careful choice
55 tients are actually unrepresented, including careful capacity assessments and diligent searches for p
56 pth analysis of this process determined that careful catalyst and solvent pairing is critical for opt
58 These studies highlight the importance of careful characterization and optimization of protocols f
59 ng genetic events and highlight the need for careful characterization of each line to assure interpre
60 ent and validation conditions should require careful characterization of the performance data prior t
62 it is demonstrated that through a simple yet careful choice of cluster size and organic ligands, stab
63 understanding of absence seizures and demand careful choice of initial monotherapy and continuous neu
64 by careful candidate assessment, and 2) the careful choice of phenotypes, often extremes of a quanti
65 and stability can be primarily ascribed to a careful choice of the interfacial layout in the layer st
70 arterial events after MPN diagnosis deserve careful clinical surveillance for early detection of car
74 etal-organic frameworks (MOFs), in which the careful combination of organic ligands with metal-ion no
78 ged with mechanical support may require more careful consideration for transplant eligibility after L
79 lvic pain and sexual function which requires careful consideration in counselling patients for this p
80 is likely to continue to be widespread, and careful consideration is required by rheumatologists to
84 ted for purposes other than research require careful consideration of data quality as well as the gen
85 ng global efforts, longitudinal designs, and careful consideration of developmental stages, and sex a
87 include forensic applications, necessitating careful consideration of ethical and legal implications
89 nergy homeostasis and highlight the need for careful consideration of its development as a safe antio
91 gement of MM in the era of COVID-19 requires careful consideration of patient- and disease-related fa
93 immunodeficiency viruses (HCV; HIV) requires careful consideration of potential drug-drug interaction
94 with a history of a major bleeding warrants careful consideration of such therapy in these patients.
95 panel test for clinical diagnostics requires careful consideration of the inclusion of appropriate di
97 nes may be missed, highlighting the need for careful consideration of the specific approach used to m
100 es; however, before clinical implementation, careful consideration should be given to case selection
101 impart significant infectivity differences, careful consideration should be given to drawing conclus
105 will be highlighted in this review, through careful considerations of potential sample and conformat
106 tors, although the resulting output requires careful contextual interpretation beyond generating epid
107 ) crystals has previously been performed via careful control of oriented MOF growth on substrates, as
111 nagement of multi-year droughts will require careful coordination if risks of harmful impacts are to
112 fluenza virus particle assembly involves the careful coordination of various viral and host factors t
113 arious disease processes can be evaluated by careful CT technique and proper attention to the duodenu
114 ng dialysis availability and supplies; thus, careful daily assessment of available resources is neede
119 extraordinary optical properties through the careful design and arrangement of subwavelength structur
121 rimary specimen type used for pulmonary TB), careful design and reporting of the specimen flow is ess
128 eillance to detect IFD relapse post-HSCT and careful drug selection for antifungal prophylaxis are of
130 ng-term greening efforts in drylands require careful ecohydrologic evaluation so that green and blue
131 n chemically "noisy" bioenvironments require careful engineering of nanoscale components that are hig
132 genetic variants is challenging and requires careful evaluation in the context of a patient's phenoty
136 metabolism and point out the need for a more careful evaluation of the entire purinome in emerging ca
137 nclude with an in-depth error analysis and a careful evaluation of the pros and cons of the two appro
140 llowing routine exam, suggesting the need of careful evaluation of zonular integrity on pseudopahkic
143 Our discovery underscores the importance of careful examination of regions of the genome that are ty
145 Those experimental results, supported by a careful examination of the involved orbitals, provide a
148 econd-timescale MD simulations, will allow a careful examination of the regulation of pLGICs at a mol
150 ice are viable, body weight trends lower and careful examination of tissue, cell, and brush border mo
152 ion of serrated polyps indicate the need for careful examination, with adequate bowel preparation and
153 Many cases could have been avoided with careful examinations, thorough documentation in the pati
154 tive detection of (14)C-labeled products and careful experimental set-ups enabled discrimination betw
158 ctive, these drugs require venous access and careful fetal monitoring and might not be feasible in bu
159 d implantable monitoring technology requires careful fixation for accurate detection and needs to be
170 ts should use evidence-based practices and a careful informed consent process when choosing intravitr
171 -definition white-light endoscopy, including careful inspection of the neosquamous mucosal and retrof
172 ral features, highlighting the importance of careful integration of structural features in any analys
175 rdiovascular trials, suggesting the need for careful interpretation of results, particularly when num
176 iven ion may be inferred experimentally from careful interpretation of the potentiometric selectiviti
179 been studied using time course analyses and careful isolation of photolabile intermediates with supp
181 challenging for first responders, requiring careful management of exposed persons following decontam
184 ional materials, such as semiconductors, via careful manipulation of defects has led to extraordinary
185 o health care systems worldwide but requires careful matching of blood types to avoid serious adverse
186 mingly contradictory observations requires a careful measurement of the public's perceptions of mobil
189 ntal lactate highlights the general need for careful metabolite measurements in the tumor extracellul
191 hat photosignaling of phytochromes relies on careful modulation of structural heterogeneity of the PH
196 ductive age and during pregnancy, as well as careful monitoring of infant growth to detect early exce
198 rd of OLE patients experienced DR worsening, careful monitoring should be part of the long-term manag
204 of language have differing dynamics and that careful, nuanced models of language change will be neede
205 ediate prescription of glasses compared with careful observation (with glasses only if deteriorated).
206 generations of scientific inquiry guided by careful observation and occasional serendipity, and the
207 for most symptomatic dengue patients remains careful observation and prompt but judicious use of intr
210 lighted, as is the importance of obtaining a careful occupational history in the patient presenting w
211 ve as reservoirs of the virus, necessitating careful ongoing animal management and surveillance.
213 vement in detectability was realized through careful optimization of the mirror lengths and locations
217 of the mammalian cerebral cortex depends on careful orchestration of proliferation, maturation, and
218 ntial morbidity and mortality, necessitating careful patient evaluation before operative intervention
220 Although safety data indicate the need for careful patient selection and monitoring, our preliminar
222 ng-term outcomes, and should be prevented by careful patient selection, awareness of surgeons' learni
223 pands to include a wider patient population, careful patient selection, pre-treatment cardiac evaluat
224 d we outline how future studies will require careful phenotype harmonization to properly capture the
225 ise genome editing in P patens Additionally, careful phylogenetic studies with increased resolution h
228 gful data using confocal microscopy requires careful planning and a thorough understanding of the tec
236 high levels of functional disability warrant careful prognostication of intracerebral hemorrhage outc
237 nfounders may however have persisted despite careful propensity-weighted analysis and the study might
239 taining a homogeneous fibril sample required careful purification of the protein and removal of any p
240 sis of large RNA-Seq data sets requires both careful quality control and the need to account for spar
245 very low ion concentrations or else require careful recalibration for different sample conditions.
247 and low-risk survivors is needed, including careful reconsideration of discontinuing asymptomatic le
248 et on stem cell regulation and call for more careful reporting on dietary conditions used in mouse st
252 trongly associated with outcome and warrants careful risk assessment and well-designed clinical trial
253 ) of 2% or less may be achieved by combining careful sample preparation with improved instrumentation
260 escued paralog dependency, underscoring that careful selection criteria must be employed to identify
264 urements, the premise of qHNMR relies on the careful selection of integrals, for both the analyte and
270 irectional motion in myosin V is examined by careful simulations that include two complementary direc
271 effective interventions, and should involve careful statistical approaches and multidisciplinary col
272 portance of accurate electrode placement and careful stimulation titration in the prevention of neuro
273 e-consuming, and to facilitate this process, careful structural analysis beyond the antibody binding
278 sing survival is compelling and necessitates careful study and the analysis of well-designed clinical
279 not without their limitations; however, with careful study design and sample handling, these methods
280 ant targets and mechanisms of action through careful study of biological changes resulting from these
282 driven by changes in antimicrobial use, but careful study of this association requires the use of ti
284 e orders, there remains a continued need for careful surgical scheduling because we must face the rea
292 at maxillary anterior teeth and necessitate careful treatment planning to prevent future complicatio
293 or strain around the sphere, which requires careful tuning of the viscous boundary layer on the movi
294 se, their use must be considered alongside a careful understanding of the behaviors and populations t
296 affects lipid metabolism in macrophages, 3) careful validation of experimental conditions and result
298 low frequencies, so their analysis requires careful variant annotation and very large sample sizes(1
299 ypes of manipulations can be detected with a careful visual examination, our visual system seems unab