ライフサイエンスコーパス: cartilaginous

1 littermates and their skeletons were largely cartilaginous.

2 isiform insertion of ligament or muscle with cartilaginous abnormalities of the PTJ was assessed.

3 Infection of human cartilaginous airway epithelium (HAE) and a hamster mode

4 rast, differentiated epithelial cells in non-cartilaginous airways maintain quiescence by activating

5 re, we show that during homeostasis, BSCs in cartilaginous airways maintain their stem cell state by

6 Non-cartilaginous airways neutrophilia was inversely correla

7 d promotes basal cell differentiation in the cartilaginous airways.

8 s (BSCs) in the protected environment of the cartilaginous airways.

9 ) are a prominent structure that lines human cartilaginous airways.

10 tive or chemical material, to impede further cartilaginous and bony deterioration.

11 ty-nine marine vertebrate species, including cartilaginous and bony fish and marine reptiles, from no

12 dine deaminase (AID), an enzyme expressed in cartilaginous and bony fish that is also required for so

13 It is absent in cartilaginous and bony fish, and it is common to all tet

14 hagfish) and gnathostomes (jawed vertebrates-cartilaginous and bony fishes), based on their distinct

15 molecule (BALM) has also been identified in cartilaginous and bony fishes, and we report in this stu

16 d fins are exemplified by extinct and extant cartilaginous and bony fishes.

17 of the two living gnathostome lineages: the cartilaginous and bony vertebrates.

18 in the formation of periodically alternating cartilaginous and non-cartilaginous domains in the ventr

19 of the alpha1(XI) collagen (COL11A1) gene in cartilaginous and non-cartilaginous tissues and in coord

20 of electroreceptors and ampullary organs in cartilaginous and non-teleost bony fishes, and indicate

21 electric fields are used for hunting by both cartilaginous and non-teleost bony fishes.

22 ted two stratified layers of histogenesis of cartilaginous and osseous phenotypes.

23 Developing cartilaginous and ossified skeletal anlagen is encapsula

24 have focused on marine animals (cnidarians, cartilaginous and ray-finned fishes) but we know compara

25 imals, including cnidarians, arthropods, and cartilaginous and ray-finned fishes.

26 ite 2HG were measured in a series of central cartilaginous and vascular tumors, including samples fro

27 and interpretation of meniscal, ligamentous, cartilaginous, and synovial disorders within the knee th

28 formation and more strikingly, boosted digit cartilaginous anlaga elongation, synovial joint formatio

29 re required for the vascular invasion of the cartilaginous anlage and the ossification of long bones.

30 We describe new evidence for a notochord, cartilaginous arcualia, gill pouches, articulations with

31 st accuracy for the detection of osseous and cartilaginous bodies combined (92%) and was significantl

32 allus formation, and could be used to induce cartilaginous callus formation.

33 (VNO) is a chemoreceptor organ enclosed in a cartilaginous capsule and separated from the main olfact

34 Development of the cartilaginous capsule of the inner ear is dependent on i

35 information gleaned mostly from both modern cartilaginous (chondrichthyan) and bony (osteichthyan) f

36 oliferation of limb bud mesenchyme and small cartilaginous condensations, and syndactyly is associate

37 attern and formation of additional postaxial cartilaginous condensations.

38 on of dense nodules reminiscent of embryonic cartilaginous condensations.

39 Cartilaginous constructs were engineered by using bovine

40 Both environments yielded cartilaginous constructs, each weighing between 0.3 and

41 ow a range of joint abnormalities, including cartilaginous continuities between juxtaposed skeletal e

42 Because it is expressed primarily in the cartilaginous cores of developing long bones during embr

43 al flexor tendons passed through cartilages, cartilaginous cristae and ridges on the plantar side of

44 centuries these have been overlooked as mere cartilaginous curiosities.

45 in a hydrogel and injected into the embedded cartilaginous cylinders following removal of the silicon

46 CFTR(-/-) mice exhibited similar congenital cartilaginous defects that may reflect a common Cl(-) se

47 B-8 interface, linking EIIIB to skeletal and cartilaginous development, wound healing, and tumorigene

48 Bone elongation originates from cartilaginous discs (growth plates) at both ends of a gr

49 riodically alternating cartilaginous and non-cartilaginous domains in the ventral mesenchyme.

50 silon-caprolactone) scaffold, induced robust cartilaginous ECM formation by hMSCs.

51 for the stylopod initiates normally but the cartilaginous element subsequently fails in growth, chon

52 node grafts often contain elongated, jointed cartilaginous elements arranged in three distinct proxim

53 How do cartilaginous elements attain their characteristic size

54 Bioassays revealed that cartilaginous elements in Day 5.5, 8.5, and 10 chick emb

55 lood vessel reduction in the vicinity of the cartilaginous elements in the Vegfa CKO mice raise the p

56 tion of Ihh, normal expression of Ihh in the cartilaginous elements is retained.

57 dynamic and distinct expression patterns in cartilaginous elements of developing chicken limbs.

58 The cartilaginous elements of each arch are formed from sepa

59 EGF are not detected in the differentiating cartilaginous elements or muscle primordia of the limb,

60 se to the condensations and subsequently the cartilaginous elements that serve as the templates of th

61 nal inactivation of murine VHL (Vhlh) in all cartilaginous elements to investigate its role in endoch

62 Interestingly, the transgenic cartilaginous elements were ill defined, intermingled wi

63 Bmpr1b in cartilage are able to form intact cartilaginous elements, double mutants develop a severe

64 mice display ectopic mineralization in many cartilaginous elements.

65 the failure of fusion or the elimination of cartilaginous elements.

66 and found reduced cranial size and abnormal cartilaginous elements.

67 Sequence comparison between human and the cartilaginous elephant shark (Callorhinchus milii) revea

68 vasive estimation of the degeneration of the cartilaginous end plate; however, the accuracy of T2*-ba

69 ied at ages 51, 57, and 66 years) containing cartilaginous end plates and subchondral bone were prepa

70 ciently marked that the mice are born with a cartilaginous endochondral skeleton.

71 d limbs in Xenopus adult frogs, which have a cartilaginous endoskeleton surrounded by connective tiss

72 er group of osteichthyans and have primarily cartilaginous endoskeletons, long considered the ancestr

73 f LCM to the gene expression analysis of the cartilaginous epiphyseal growth plate of normal newborn

74 During fetal development, the cartilaginous epiphysis of the distal femur transformed

75 on in MR imaging signal intensity within the cartilaginous epiphysis of the distal femur.

76 The underlying cartilaginous epiphysis was deranged as well and display

77 stem cell differentiation and formation of a cartilaginous extracellular matrix (ECM) using a lentivi

78 The cartilaginous extracellular matrix produced by the cultu

79 Cartilaginous fish (e.g., sharks) are derived from the o

80 Cartilaginous fish (sharks, skates, and rays) are in the

81 d to have recombined with the TRD locus in a cartilaginous fish ancestor >200 million years ago and e

82 the SCPP genes arose after the divergence of cartilaginous fish and bony fish, implying that early ve

83 in this sense, the TCR-beta genes in this cartilaginous fish and humans are more similar than are

84 fide bonds found in new antigen receptors of cartilaginous fish and in camelid heavy-chain variable d

85 hologous to IgW, an Ig isotype found only in cartilaginous fish and lungfish, demonstrating that IgD/

86 Ig genes in cartilaginous fish are encoded by multiple individual lo

87 Cartilaginous fish are the oldest animals that generate

88 The cartilaginous fish are the oldest phylogenetic group in

89 Cartilaginous fish are the phylogenetically oldest livin

90 Sharks and other cartilaginous fish are the phylogenetically oldest livin

91 lements can be identified through the use of cartilaginous fish as a baseline.

92 We have established a cartilaginous fish cell line [Squalus acanthias embryo c

93 prerequisite for their identification, this cartilaginous fish culture system also provides a physio

94 a neural crest origin has been proposed for cartilaginous fish electroreceptors.

95 Minor differences between the bony and cartilaginous fish enhancers account for their restricte

96 hat Spi-D arose before the divergence of the cartilaginous fish from the lineage leading to the mamma

97 The recent cartilaginous fish genome project suggests that most eff

98 ding to the detection of type I IFN genes in cartilaginous fish genomes, the system appeared 500 My a

99 These molecular data suggest that cartilaginous fish have augmented their humoral immune r

100 he Tm and secretory (Sec) mRNAs of the novel cartilaginous fish Ig isotypes, IgW and IgNAR, are prese

101 to account for poor immune responsiveness in cartilaginous fish should be abandoned.

102 roup that includes tetrapods, and more basal cartilaginous fish showed pectoral innervation that was

103 s assessed in the context of up to 117 other cartilaginous fish species, using phylogenetic comparati

104 Eos in Raja eglanteria (clearnose skate), a cartilaginous fish that is representative of an early di

105 ervation of the Ikaros multigene family from cartilaginous fish through mammals, these studies define

106 leotides) are significantly smaller than the cartilaginous fish TRs (478-559 nucleotides) and tetrapo

107 ric TCRs containing amphibian, bony fish, or cartilaginous fish Vbetas can recognize antigens present

108 rectifying Kv channel predicted from skate (cartilaginous fish) ampullary organ electrophysiology.

109 Chondrichthyans (cartilaginous fish) are the most distant group to amniot

110 albumin in a comprehensive range of bony and cartilaginous fish, from the Asia-Pacific region, and co

111 In most jawed vertebrates including cartilaginous fish, membrane-bound IgM is expressed as a

112 he PU.1 family of transcription factors in a cartilaginous fish, Raja eglanteria, are described here.

113 fin development in embryos of the primitive cartilaginous fish, Scyliorhinus canicula (dogfish) usin

114 ere we report the whole-genome analysis of a cartilaginous fish, the elephant shark (Callorhinchus mi

115 s of the Dlx gene family of a representative cartilaginous fish, the leopard shark, Triakis semifasci

116 by cell lineage tracing that the gills of a cartilaginous fish, the little skate (Leucoraja erinacea

117 of trunk neural crest cells in embryos of a cartilaginous fish, the little skate (Leucoraja erinacea

118 the four TCR chains for the first time in a cartilaginous fish, the nurse shark (Ginglymostoma cirra

119 ates; however, its activator is not known in cartilaginous fish, the oldest group of extant jawed ver

120 ationship between somites and vertebrae in a cartilaginous fish, the skate (Leucoraja erinacea).

121 represents the oldest vertebrate class, the cartilaginous fish, with adaptive immunity provided via

122 long-term in vivo fate-mapping study in any cartilaginous fish.

123 ification of TCR-expressing lymphocytes in a cartilaginous fish.

124 n the common ancestor of the mammals and the cartilaginous fish.

125 ajor histocompatibility complex genes from a cartilaginous fish.

126 an and epigonal tissues, which are unique to cartilaginous fish.

127 existed not long before the emergence of the cartilaginous fish.

128 eak" adaptive immune responses documented in cartilaginous fish.

129 iversification and clonal selection exist in cartilaginous fish.

130 and the adult skeleton of modern jawless and cartilaginous fish.

131 all fish analysed, except for gummy shark a cartilaginous fish.

132 complete loss of reactivity was observed for cartilaginous fish.

133 be identified in lineages as far as that of cartilaginous fish.

134 kedly diversified in the lineages leading to cartilaginous fishes (Chondrichthyes) and bony vertebrat

135 w years, the detailed revision of the Eocene cartilaginous fishes (Chondrichthyes) from the Bolca Lag

136 The cartilaginous fishes (Chondrichthyes) have a rich fossil

137 hin the specialized electrosensory organs of cartilaginous fishes (Chondrichthyes).

138 Cartilaginous fishes (e.g., sharks and skates) possess a

139 We studied two cartilaginous fishes and described their brainstem supra

140 s subsequently diverged into two groups, the cartilaginous fishes and the bony vertebrates.

141 teral line placodes form electroreceptors in cartilaginous fishes by undertaking the first long-term

142 The IgM H chain gene organization of cartilaginous fishes consists of 15-200 miniloci, each w

143 secreted calcium-binding phosphoproteins in cartilaginous fishes explains the absence of bone in the

144 Furthermore, the adaptive immune system of cartilaginous fishes is unusual: it lacks the canonical

145 ally as is the case in many chondrichthyans (cartilaginous fishes) and osteichthyans (bony fishes and

146 es, including reptiles, amphibians, bony and cartilaginous fishes, and cyclostomes, features a great

147 ignificantly related to body mass for birds, cartilaginous fishes, and mammals.

148 are present in jawed vertebrates, including cartilaginous fishes, but not in jawless vertebrates or

149 ation occurred in an ancestor in common with cartilaginous fishes, giving rise to a separate p53 gene

150 Cartilaginous fishes, or chondrichthyans, are the oldest

151 asmobranchs, or is the ancestral pattern for cartilaginous fishes, requires examination of a represen

152 In cartilaginous fishes, the immunoglobulin (Ig) light chai

153 Moreover, unlike other cartilaginous fishes, there are no germline-joined VDJ a

154 In cartilaginous fishes, variability in the size of the bra

155 lineages of jawed vertebrates, including the cartilaginous fishes, which represent the most phylogene

156 first to show that the pattern is present in cartilaginous fishes.

157 tion diversity that evolved independently in cartilaginous fishes.

158 elements resembling the multimeric covers of cartilaginous fishes.

159 l motoneurons is the primitive condition for cartilaginous fishes.

160 udes the Wnt9 sequences found in jawless and cartilaginous fishes.

161 sus separate covers for each gill chamber in cartilaginous fishes.

162 rescence has evolved at least three times in cartilaginous fishes.

163 up is represented by the chondrichthyans, or cartilaginous fishes.

164 e of facial prominences and extension of the cartilaginous framework.

165 Cartilaginous growth plate abnormalities persisted in ad

166 owever, it causes structural collapse of the cartilaginous growth plate as a result of impaired proli

167 pressed in proliferating chondrocytes of the cartilaginous growth plate but also in chondrocytes that

168 n, affects many tissues, most strikingly the cartilaginous growth plate in the growing skeleton, lead

169 elete HIF-1alpha in an avascular tissue: the cartilaginous growth plate of developing bone.

170 s coordinately with growth of the underlying cartilaginous growth plate.

171 ing and hypertrophic chondrocytes within the cartilaginous growth plate.

172 mammalian target of rapamycin (mTOR) in the cartilaginous growth plate.

173 and remodeling and in the development of the cartilaginous growth plates of endochondral bone.

174 tants were analyzed for abnormalities in the cartilaginous head skeleton.

175 on is carried out by the earlier developing, cartilaginous incus of the middle ear, abutting the cran

176 Our results link low-grade IL-8-mediated cartilaginous inflammation in OA to altered chondrocyte

177 ed abnormal epiphyseal cartilage thickening, cartilaginous islands within ossified tissue, and less f

178 follistatin a (fsta) and emx2, in regulating cartilaginous joints in the hyoid arch.

179 se in sulfate incorporation into GAGs in the cartilaginous layer as though the tissue measured was fr

180 Because avian sclera has a cartilaginous layer as well as the fibrous layer found i

181 on as does the mammalian sclera, whereas the cartilaginous layer changes in the opposite direction.

182 The responses of the cartilaginous layer may be controlled by the fibrous lay

183 bited by atropine in whole sclera and in its cartilaginous layer.

184 In the cartilaginous layers, the incorporation of label into pr

185 null vascular disease presents as calcifying cartilaginous lesions and mineral deposition along elast

186 The association between cartilaginous lesions and osteoarthritic changes was cal

187 Cartilaginous lesions and osteophytes were easily identi

188 High-grade cartilaginous lesions can be evaluated reliably with low

189 p(-/-) mice dramatically reduced the size of cartilaginous lesions in the aortic media, attenuated ca

190 Subsequently, primary cartilaginous lesions within the epiphyseal cartilage de

191 lity in Mgp(-/-);Tgm2(-/-) mice with reduced cartilaginous lesions.

192 Chondroblastomas are benign cartilaginous lesions; however, intervention is necessar

193 During limb skeletogenesis the cartilaginous long bone anlagen and their growth plates

194 nulomatous lesions and residual degenerating cartilaginous masses are also present in the bones of th

195 d fused with each other into large amorphous cartilaginous masses.

196 surgical excision of the ossicle and/or free cartilaginous material may give good results in skeletal

197 te differentiation affects mineralization of cartilaginous matrix in a non-cell autonomous fashion; m

198 emonstrated a more dense, negatively charged cartilaginous matrix in control cultures.

199 regulated collagen modification renders the cartilaginous matrix more resistant to protease-mediated

200 tilage, fibrocartilage, and a nonmineralized cartilaginous matrix with lacunae containing chondrocyte

201 However, the main constituents of the cartilaginous matrix, aggrecan and type II collagen, are

202 with collagen IX that could destabilize the cartilaginous matrix.

203 and skeletogenesis, is also expressed in pre-cartilaginous mesenchymal condensations in the developin

204 organ anlage that was dependent upon midline cartilaginous/mesenchymal tissues.

205 In 75% of Cthrc1 transgenic mice, cartilaginous metaplasia of medial smooth muscle cells w

206 e cell phenotype and provide an etiology for cartilaginous metaplasia of the arterial wall.

207 d a cellular and matrix-rich neointima, with cartilaginous metaplasia of the vascular media.

208 Between 4 and 8 weeks, the cartilaginous metaplasia resolved and the intimal lesion

209 The synovium was hyperplastic, and cartilaginous metaplasia was observed in the joint space

210 nother case and a focus of mineralised fibro-cartilaginous metaplasia with endochondral ossification

211 liest manifestation, the lesion was entirely cartilaginous (n = 1).

212 interface between the nasal bone process and cartilaginous nasal septum.

213 then Sox9 expression was induced, leading to cartilaginous nodules and particles in the presence of B

214 MPC proliferation, underlying multiplex non-cartilaginous OA conditions including synovial hyperplas

215 her terrestrial vertebrates, is not found in cartilaginous or ray-finned fish.

216 hondrium becomes deranged and interrupted by cartilaginous outgrowths in Hereditary Multiple Exostose

217 e associated with defective formation of the cartilaginous pharyngeal skeleton.

218 beta-NGF injections during the endochondral/cartilaginous phase promoted osteogenic marker expressio

219 re repair, finding that they peak during the cartilaginous phase.

220 Otor and Col2A1 are coexpressed in the cartilaginous plates of the neural and abneural limbs of

221 y a patchy mode of ossification of a massive cartilaginous precursor and that the predigits act funct

222 , sphenoid and ethmoid bones that arise from cartilaginous precursors in the early embryo.

223 ondensation, but alters the formation of the cartilaginous primordia.

224 and KAT, but not collagen type II (ColII), a cartilaginous protein.

225 um likely caused the short bones and ectopic cartilaginous protrusions.

226 region encoded by exon IIIA disappears from cartilaginous regions just after condensation in vivo an

227 Pln mRNA and protein are highly expressed in cartilaginous regions of developing mouse embryos, but n

228 lialized sites as well as in chondrocytes in cartilaginous regions of the embryo.

229 taphysis), signal intensity and thickness of cartilaginous regions seen on MR images were correlated

230 ginous regions and from 200 to 210 mmol/L in cartilaginous regions.

231 he growth plate, and a prolonged presence of cartilaginous remnants in the spongiosa, confirming a de

232 diameter conducting airways are supported by cartilaginous rings and smooth muscle tissue and are lin

233 e in the perichondrium surrounding avascular cartilaginous rudiments; the source of trabecular osteob

234 Coculturing cartilaginous sclera from normal eyes with fibrous scler

235 or was expressed by cells in the fibrous and cartilaginous sclera in equatorial regions of the eye.

236 ecially from recovering eyes, also inhibited cartilaginous sclera.

237 th uncouples the lateral expansion of curved cartilaginous sheets from the control of cartilage thick

238 -deficient mice fail to remodel the primary, cartilaginous skeletal anlagen.

239 ments that enforces a distortion of the soft cartilaginous skeletal elements and bone shapes.

240 inuous Wnt/beta-catenin signaling in nascent cartilaginous skeletal elements blocks chondrocyte hyper

241 Through programmed tissue substitution, the cartilaginous skeletal model is replaced by trabecular b

242 accompanied by a severe dysmorphology of the cartilaginous skeleton and failure of maturation of seve

243 -1 counterpart (hERG3Delta81) throughout the cartilaginous skeleton of transgenic mice, using Col2a1

244 that are expressed during development of the cartilaginous skeleton.

245 imarily through the growth plate, which is a cartilaginous structure at the end of long bones made up

246 essed in and function in the growth plate, a cartilaginous structure that causes bone elongation and

247 The epiphysis of developing bones is a cartilaginous structure that is eventually replaced by b

248 Cartilaginous structures are at the core of embryo growt

249 Certain embryonic bones and cartilaginous structures develop abnormally, with verteb

250 and Col2a1-Cre/R26R lines indicated that non-cartilaginous structures in the knee such as cruciate li

251 which contribute to a subset of the bony and cartilaginous structures of the skull.

252 In particular, fibrocartilaginous and cartilaginous structures on the plantar surface of the a

253 tracheal equivalent composed of cylindrical cartilaginous structures with lumens lined with nasal ep

254 icer results in embryos lacking craniofacial cartilaginous structures, cardiac outflow tract septatio

255 r grafts, tracheal splints, heart tissue and cartilaginous structures.

256 structural and functional changes in the two cartilaginous structures.

257 in all species analyzed within the two major cartilaginous subclasses, Holocephali (chimaeras) and El

258 The tendon sheath, the fibrous capsule, and cartilaginous surfaces were better visualized at MR arth

259 lature intimately associated with the pelvic cartilaginous symphysis-a noncapsulated cartilage with a

260 rsal and caudal fins absent; tail stings and cartilaginous tail rod absent; and teeth of dasyatoid mo

261 It develops as a cartilaginous template that is replaced by bone through

262 ainly by the human cells and formed over the cartilaginous template.

263 y B. burgdorferi components can persist near cartilaginous tissue after treatment for Lyme disease.

264 nd signaling molecules during development of cartilaginous tissue and is essential for proper chondro

265 m cell therapy could enhance regeneration of cartilaginous tissue and serve as a potential therapeuti

266 native ECM, the nanofiber scaffolds enhanced cartilaginous tissue formation, suggesting their potenti

267 Correlations between cartilaginous tissue function and MR imaging parameters

268 ded with cells and so provide a template for cartilaginous tissue growth.

269 s (OA), characterized by degeneration of the cartilaginous tissue in articular joints, severely impai

270 applications in monitoring the integrity of cartilaginous tissue in vivo.

271 dues of nonviable spirochetes can persist in cartilaginous tissue long after treatment and may contri

272 ression was also seen in the skin and in the cartilaginous tissue of developing skeleton.

273 of musculoskeletal degeneration in bony and cartilaginous tissue regions.

274 biomechanical characteristics of this fibro-cartilaginous tissue.

275 ter candidate than PA MSCs for the repair of cartilaginous tissue.

276 tients show diffuse ectopic calcification of cartilaginous tissues and impaired midface development.

277 agen (COL11A1) gene in cartilaginous and non-cartilaginous tissues and in coordination with different

278 nique, rare autoimmune disorder in which the cartilaginous tissues are the primary targets of destruc

279 In addition, overgrowth of the cartilaginous tissues is observed in the rib cartilage,

280 aracterized by recurrent inflammation of the cartilaginous tissues of the ears, nose, peripheral join

281 proliferated and differentiated, but ectopic cartilaginous tissues protruded into the perichondrium.

282 lation of aggrecan, a major ECM component of cartilaginous tissues that confers resistance to compres

283 cartilage (AC) and intervertebral discs are cartilaginous tissues with a similar biochemical composi

284 zed by recurrent episodes of inflammation of cartilaginous tissues, can be life-threatening, debilita

285 te that the novel SLRP CHADL is expressed in cartilaginous tissues, influences collagen fibrillogenes

286 In non-cartilaginous tissues, type I collagen accounts for the

287 mineralized structures but also in soft and cartilaginous tissues.

288 gulatory molecules that have a major role in cartilaginous tissues.

289 mferentially continuous or nearly continuous cartilaginous tracheal rings, variable degrees of trache

290 stenosis because of incomplete formation of cartilaginous tracheal support.

291 he characteristic chemotherapy resistance of cartilaginous tumors (overexpression of P-glycoprotein)

292 Although some cartilaginous tumors are characterized by specific or re

293 ic skeletal disorder characterized by benign cartilaginous tumors called exostoses that form next to

294 ndrome are characterized by multiple central cartilaginous tumors that are accompanied by soft tissue

295 A separate subset of 116 cartilaginous tumors with outcome data was used for vali

296 In the validation arm of 116 cartilaginous tumors, MYC was frequently amplified in G2

297 ers, 31 other CNS-tumors, and 120 IDH-mutant cartilaginous tumors, we identified that the association

298 cation and therapy of this diverse family of cartilaginous tumors.

299 Hypoxia-preconditioned implants remained cartilaginous, whereas normoxia-preconditioned implants

300 ormly distributed throughout the fibrous and cartilaginous zones of the TMJ condyle.