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2 ils occurred nearly instantly when PTI-00703 cat's claw and Abeta fibrils were mixed together as show
4 s and specific constituents within PTI-00703 cat's claw responsible for both the observed "plaque" an
8 e fecal microbiome of 38 healthy cats and 27 cats with CE (13 cats with IBD and 14 cats with SCL).
10 largest feline autopsy cohort to date of 32 cats ranging from 1.5 to 22.1 years of age, with systema
11 in Cortical Layers IV and VI in 27 of the 32 cats used in the study, with four of these animals showi
13 c cat versus domestic dog (51%, n = 32 of 62 cats; 15%, 11 of 70 dogs were positive for CIN, respecti
14 assessed the bioavailable FR exposures of 78 cats (>=7 y) in New York and Oregon using gas chromatogr
18 broblast cell line, derived from an affected cat from the original colony, was whole genome sequenced
22 to birch as well as grass pollen Phl p 1 and cat Fel d 1 allergen molecules may be related to specifi
23 e family AAA domain containing 2 (ATAD2) and cat eye syndrome chromosome region, candidate 2 (CECR2)
27 compared to those pre-1989 (p < 0.002), and cats preferring to spend time on upholstered furniture i
32 rd injury, mammals, including mice, rats and cats, recover hindlimb locomotion with treadmill trainin
33 orded LGN spike trains from the anesthetized cat to a detailed model of a spiny stellate V1 neuron, w
34 mice do not follow the same organization as cats suggesting that the transthalamic pathways play dis
35 ful experimental infections of pets, such as cats, ferrets and dogs, raises questions about the susce
37 , progressive retinal degeneration in Bengal cats; we identified a c.1000G>A (p.Ala334Thr) KIF3B vari
40 uction complex binds and phosphorylates beta-cat and transfers it to the SCF-TrCP E3-ubiquitin ligase
43 ing of pro vs. anti-oxidant minerals between cats and dogs, further in vivo balance studies are warra
44 , as well as the TL and the DMA laws; bigger cat species showed less variation for the population den
46 sine kinase 2 (TYK2) that is present in both cat and cow, as well as a family of mirtrons with two in
48 population, the diabetic Australian Burmese cat provides a spontaneous genetic model for studying di
53 ver, the colonies were disbanded and the CHS cat model was lost to the research community before the
54 ata from 5038 pedigree-registered Maine Coon cats in a radiographic health screening programme for FH
57 seropositive person reported multiple direct cat exposures without using personal protective equipmen
60 sts we investigated, ACE2 proteins from dog, cat, and cattle were the most permissive to SARS-CoV-2,
61 aspects of non-murine models, including dog, cat, pig, zebrafish, and frog, that could be used to inv
62 anel of animal models, i.e. guinea pig, dog, cat, rat, rabbit, ferret, mouse, hamster and macaque.
63 ng for familial atopic disease, maternal dog/cat sensitization and participant AD, living with dogs w
68 minutum (CMhm) (15.7% guigna; 10.3% domestic cat) and Mycoplasma haemofelis (Mhf) (9.8% guigna, 6.1%
69 o FeLV than domestic cat cells, and domestic cat FeLV restriction was highly related to enFeLV-LTR co
70 cument a strong association between domestic cat cell susceptibility and FeLV long terminal repeat (L
72 elid species other than the endemic domestic cat host, differences in FeLV susceptibility among speci
73 e present the earliest evidence for domestic cat (Felis catus L., 1758) from Kazakhstan, found as a w
74 pulation, CIN was more prevalent in domestic cat versus domestic dog (51%, n = 32 of 62 cats; 15%, 11
78 ts are more permissive to FeLV than domestic cat cells, and domestic cat FeLV restriction was highly
80 e permissive to FeLV infection than domestic cat samples, suggesting that endogenization can play a b
82 f the subgingival microbiota of the domestic cat and reveal both differences and similarities among p
89 , a common endocrinopathy affecting domestic cats, shares many clinical and pathologic features with
90 Our findings indicate that aging domestic cats spontaneously develop both beta-amyloid and tau pat
92 FeLV-infected Florida panthers and domestic cats had similar exFeLV proviral copy numbers, but Flori
93 ne Mycoplasma species in guigna and domestic cats were Candidatus M. haemominutum (CMhm) (15.7% guign
95 possibility of transmission between domestic cats and guignas by comparing spatial and phylogenetic p
96 Neolithic NE cats with the earliest domestic cats known from the territory of Poland, dating to the R
97 d primary fibroblasts isolated from domestic cats (Felis catus) and pumas (Puma concolor) with FeLV a
98 f the youngest feline ERV groups in domestic cats (Felis silvestris catus); some members are replicat
105 so measured in 6 naturally infected domestic cats and 11 naturally infected Florida panthers (P. conc
106 nonprimate lentivirus that infects domestic cats and causes a syndrome that is reminiscent of AIDS i
107 Endogenous retroviruses (ERVs) of domestic cats (ERV-DCs) are one of the youngest feline ERV groups
108 oupled plasma-mass spectrometry) of domestic cats (kidneys, n = 56; urine, n = 21), domestic dogs (ki
109 investigated the susceptibility of domestic cats and dogs to infection and potential for infected ca
113 idence for the migration of the Near Eastern cat (NE cat), the ancestor of domestic cats, into Centra
117 quencing data sets from muscle and skin from cat, from 10 tissues from cow and also from human and mo
120 omical and electrophysiological results from cats and primates, as well as recent work in the rodent,
121 of brain were obtained retrospectively from cats autopsied at the Iowa State College of Veterinary M
122 nsity per catalyst mass loading of 2000 mA g(cat.) (-1) , as well as good stability and durable catal
124 ecules dramatically, achieving 103.21 mmol g(cat) (-1) h(-1) with near-unity selectivity for CO gener
126 ovariohysterectomy of domestic short haired cats (n = 29), with time points corresponding to varying
127 Pregnant women are advised against handling cat litter, as maternal infection with T. gondii can be
128 racterize the fecal microbiome of 38 healthy cats and 27 cats with CE (13 cats with IBD and 14 cats w
133 ns, and the study of a mixed-valence {Zn(II)-cat-SQ-Zn(II)} analog have allowed elucidation of thermo
136 tep VT interconversions of the form {Co(III)-cat-cat-Co(III)} {Co(III)-cat-SQ-Co(II)} {Co(II)-SQ-SQ-C
137 the form {Co(III)-cat-cat-Co(III)} {Co(III)-cat-SQ-Co(II)} {Co(II)-SQ-SQ-Co(II)} (cat(2-) = catechol
140 rowth rules for axonal branching patterns in cat area 17, originating from the lateral geniculate nuc
144 thy (HCM) occurs as a spontaneous disease in cats, and is characterized by myocardial hypertrophy, di
146 cate that prevalent pre-existing immunity in cats is not necessarily inhibitory to AAV and highlight
148 was no difference in renal arsenic levels in cats with or without CIN, renal arsenic accumulation doe
149 eas, resembling the parcellation observed in cats and ferrets, although not all of the auditory areas
150 composite measure of post-operative pain in cats (UNESP-Botucatu MCPS tool) was evident, demonstrati
151 s in urodynamic and anesthetic parameters in cats will facilitate appropriate study-specific anesthet
152 V serotypes (AAV1 to AAV11) are prevalent in cats living in the Northeastern United States, these ant
156 ypic provirus from a naturally FeLV-infected cat, from which the FeLV Env (TG35-2) gene was previousl
161 e acylation rate but a 5-fold increase in k (cat) for ampicillin, suggesting that the K234R enzyme is
163 -links Abeta40 into dimers and oligomers (k (cat)/K(m) = 1.5 x 10(5) m(-1)s(-1)), as well as to fibri
164 ent mutations had differential effects on k (cat) and K (0.5) for catalysis, K (0.5) for substrate bi
165 s were nonviable as CO(2)-fixation rates (k (cat) (c)) were reduced >95% and CO(2)/O(2) specificity i
166 xA was active but exhibited a much slower k (cat) This mutation altered the kinetic mechanism of the
168 orders of magnitude more slowly than the k (cat) The presence of substrate enhanced C4a-hydroperoxyf
169 urred with a rate constant similar to the k (cat) The structure of AsFMO complexed with FAD at 2.08-
171 with fluxomics data, we find that in vivo k (cat)s are robust against genetic perturbations, suggesti
172 The results demonstrate that in vivo k (cat)s can solve the problem of inconsistent and low-cove
173 models, we show that the obtained in vivo k (cat)s predict unseen proteomics data with much higher pr
174 data-driven approach to estimate in vivo k (cat)s using metabolic specialist Escherichia coli strain
175 f 5.4 +/- 0.2, a pK (ES2) of 9.9 +/- 0.1 (k'(cat) = 24 +/- 2 s(-1)), a pK (E1) of 5.4 +/- 0.3, and a
177 tent (~18-fold) versicanase than ADAMTS-4 (k(cat)/K(m) 1.86 x 10(5) M(-1) sec(-1)), whereas ADAMTS-1
178 uency at pH values as low as 1.1 and 0.43 (k(cat) =1501+/-608 s(-1) and 831+/-254 s(-1) , respectivel
180 we engineer HG4, an efficient biocatalyst (k(cat)/K(M) 103,000 M(-1)s(-1)) containing key first and s
181 or and enhanced reactivity of the complex (k(cat)) enables efficient catalysis with broad functional
183 y to BiuH, and has a catalytic efficiency (k(cat/)K(M)) of 6 x 10(5) M(-1)s(-1), a K(M) for triuret o
184 ch displays the same activation energy for k(cat) as WT, as a control, we were able to further refine
186 ity) and (iii) improvements are present in k(cat) rather than just in K(M), suggesting adaptive solut
187 f is more severe (20- to 35-fold increased k(cat)/K(M) in arylesterase with 60-400-fold decreases in
188 ffects of Q215A and Y217F substitutions on k(cat)/K(m) for decarboxylation of OMP are expressed mainl
189 mutagenesis and selection, thereby raising k(cat)/K(m) 270-fold to 5 x 10(5)m(-1)s(-1), which is even
190 to 10 mM increases nucleotide specificity (k(cat)/K(m)) 12-fold largely by increasing the rate of the
192 fic methanol formation rate of 524 g(MeOH)kg(cat)(-1)h(-1) at 220 degrees C, 3.3 times higher than th
194 m as highly divergent (~22.5 Ma) from living cat species, with no detectable signs of gene flow.
198 the ability to undergo in vitro maturation, cat oocytes were vitrified using the Cryotop method in t
200 to 5.50 mug h(-1) cm(-2) (16.67 mug h(-1) mg(cat) (-1) ) and high faradaic efficiency of 26 % under a
201 gh NH(3) formation rate of 24.7 mug h(-1) mg(cat) (-1) and a high FE of 20.0 % are achieved at an ove
203 H(3) yield rate (34.0+/-3.6 mug NH3 h(-1) mg(cat.) (-1) ) and a high Faradaic efficiency (14.6+/-1.6
204 NH(3) yield rate of 69.2+/-2.5 mug h(-1) mg(cat.) (-1) , far outperforming the individual single-ato
205 and a large NH(3) yield of 21.31 ug h(-1) mg(cat.) (-1) at -0.55 V vs reversible hydrogen electrode,
206 ulation-based birth cohort we measured mite, cat, and dog allergen levels in dust samples collected f
211 or the migration of the Near Eastern cat (NE cat), the ancestor of domestic cats, into Central Europe
212 isotopes in six samples of Late Neolithic NE cat bones and further 34 of the associated fauna, includ
215 Our interpretation is that Late Neolithic NE cats were opportunistic synanthropes, most probably free
216 we compared the ecology of Late Neolithic NE cats with the earliest domestic cats known from the terr
217 xplore niche partitioning between studied NE cats and the contemporary native European wildcats.
220 the first to characterize protein content of cat ffEVs and their potential roles in sustaining meioti
227 hat the CTK complex is negative regulator of cat-3 expression by affecting its chromatin structure.
228 parisons to previous connectional studies of cat areas 20a and 20b reveal a common pattern of connect
232 They are the most common enteric pathogen of cats and dogs in developed countries and infect ~1 billi
233 ain, spinal cord and neuromuscular system of cats, rats and zebrafish, that the printed bioelectronic
235 eraction between FLG and Fel d 1 exposure on cat sensitization, with the effect of exposure being sig
241 present a case of early childhood-onset pork-cat syndrome possibly due to sensitization by both cats
245 municatory significance of a widely reported cat behaviour that involves eye narrowing, referred to a
246 DeSantis et al. that claimed that sabertooth cats and dire wolves did not compete for similar prey.
247 A paired comparison of teeth from the same cat with and without signs of resorption identified 1,73
248 le, tunable lasers that create a Schrodinger cat state, where the system is simultaneously in a mixtu
249 tinct classical states-so-called Schrodinger cat states-are a resource for quantum metrology, quantum
250 r logical MBQC and a generalised Schrodinger cat state is used for a continuous-variable (CV) logical
251 Now that the feasibility of Schrodinger cat spectroscopy has been demonstrated, the future is op
252 generation and stabilization of Schrodinger cat states based on the interplay between Kerr nonlinear
253 luding camels, cattle, horses, goats, sheep, cats, rabbits, and pangolins, were able to support cell
255 primary domestic cat host and related small cat species harbor a related endogenous virus in their g
256 of a different chemical class increase SOS1(cat)-mediated nucleotide exchange on RAS and display cel
259 ding antibodies were highly prevalent in SPF cats (83%), but this was primarily due to cross-reactivi
260 0 feral, and 30 specific pathogen-free (SPF) cats for pre-existing AAV-binding antibodies against the
262 sing speed were similar in intact and spinal cats during backward locomotion and strategies were simi
265 perimenter provided the slow blink stimulus, cats had a higher propensity to approach the experimente
267 d in the human infant literature [5,6], that cats display distinct attachment styles toward human car
272 rward, we must proceed by understanding that cats are not exclusively pets or pests, but both a centr
274 allergen Phleum pratense 1 (Phl p 1) and the cat allergen Felis domesticus 1 (Fel d 1) greater than 3
276 Transduction was widely distributed in the cat brain, including in the cerebral cortex, an importan
277 a hu.32 serotype vector was evaluated in the cat homologue of the human lysosomal storage disease alp
279 with previous studies of connectivity in the cat, identified the posteromedial lateral suprasylvian v
280 lates the RNAPII CTD at Ser2 residues in the cat-3 ORF region during transcription elongation and del
287 y BRD inhibitor NVS-CECR2-1 that targets the cat eye syndrome chromosome region, candidate 2 (CECR2).
289 ty of FHD symptoms in descendants, but these cats were also smaller than their ancestors (-33g per ge
295 Fish-flavoured foods are more often fed to cats than dogs, and such foods tend to have higher arsen
297 was a genus of large-bodied scimitar-toothed cats, morphologically distinct from any extant felid spe
300 (FIV), which infects both domestic and wild cats, encodes a non-consensus myristoylation sequence no