ライフサイエンスコーパス: cataractous

1 inhibition, retain their LFC nuclei, and are cataractous.

2 were determined in young, precataractous and cataractous alphaA knockout lenses.

3 GSH levels decreased with increasing age in cataractous alphaA(-/-) lenses but not in the noncatarac

4 RNAs from 50 pooled cataractous and 25 pooled noncataractous epithelia were

5 Cataractous and aged human lenses were hydrolyzed and fr

6 and insoluble (WIS; P < 0.05) fractions from cataractous and normal lenses.

7 in gene expression were detected between the cataractous and the noncataractous epithelia.

8 WI) lens fractions from young, aged, nuclear cataractous, and brunescent cataractous lenses.

9 Cataractous canine LEC demonstrated significantly (P < 0

10 Normal and cataractous canine LECs were evaluated for expression of

11 choroidal coloboma is associated with early cataractous changes.

12 erminus, observed in the control nuclear and cataractous cortical membranes, was not observed in the

13 were immunoprecipitated from young, old, and cataractous crystallins using affinity-purified CML anti

14 s the baby boomer population moves into the "cataractous decades," the number of patients requiring c

15 omly selected single eye in bilateral cases; cataractous eye in unilateral cases) and to compare the

16 AL of the unilateral cataractous eye was significantly shorter than that of t

17 compare the biometry data of the unilateral cataractous eye with the data of the corresponding nonca

18 kening, and cataract surgery in an initially cataractous eye.

19 was significantly longer (p = 0.013) in the cataractous eyes (mean = 23.38 2.08 mm) of Group A(bilat

20 To report the biometry data of pediatric cataractous eyes (randomly selected single eye in bilate

21 dwork for calculating pediatric IOL power in cataractous eyes by using pediatric ocular measurements.

22 custom intraocular lenses (IOLs) than normal cataractous eyes despite the effect of misalignment on t

23 Cataractous eyes have an abnormal axial length developme

24 The mean AL of cataractous eyes in group B (unilateral cataract) (mean

25 Fifty cataractous eyes scheduled for surgery between July and

26 Cataractous eyes that deviated from the middle quartiles

27 r estrone treatment reduced the incidence of cataractous eyes to 12% or 25%, respectively.

28 Reduced signal strength in cataractous eyes was found in 65% of the 800-nm OCT imag

29 nt correlation between age and AL in case of cataractous eyes.

30 erior visualization of the posterior pole in cataractous eyes.

31 The H-chain identified in cataractous fiber cells (29 kDa) differed from the 21-kD

32 RC causes age-onset cataract in mice and the cataractous human lens has increased expression of osteo

33 Young, old, and cataractous human lens protein fractions were glycated w

34 tein was readily detected in the cortex of a cataractous human lens.

35 llin mutation was detected in an age-matched cataractous human lens.

36 Calcium is elevated in most cataractous human lenses and may contribute to cataracto

37 f a novel process occurring predominately in cataractous human lenses.

38 n of these domains in membranes of clear and cataractous human lenses.

39 se of blindness worldwide, is to extract the cataractous lens and implant an artificial intraocular l

40 ystallin is bound to the membrane of old and cataractous lens cells in vivo.

41 binding, and generation of free radicals by cataractous lens crystallins can be duplicated by ascorb

42 ly correlated (r = +0.58), suggesting that a cataractous lens does not influence the MP measurement t

43 Cell density in cataractous lens epithelia was similar to that in normal

44 owever, no method to halt the formation of a cataractous lens has been shown to be effective.

45 be part of a defense mechanism by which the cataractous lens limits iron-catalyzed oxidative damage.

46 rison of diffraction patterns indicated that cataractous lens membranes contained more pronounced and

47 The cataractous lens opacity decreases as the mice age.

48 y examine the structural organization of the cataractous lens plasma membrane versus control.

49 Enzyme-digested cataractous lens proteins displayed 3OHKYN-derived modif

50 showed consistently stronger reactions with cataractous lens proteins than those from noncataractous

51 Brunescent cataractous lens proteins were digested by enzymes, the

52 acquired in 100-mum steps across normal and cataractous lens sections.

53 d female presented with a partially absorbed cataractous lens that was dislocated into the anterior c

54 shi et al. toward the dream of replacing the cataractous lens with a flexible artificial lens, suppor

55 umulation of light-scattering centers in the cataractous lens.

56 a novel L52F alphaA-crystallin mutation in a cataractous lens.

57 of higher order associates in the aging and cataractous lens.

58 f Na,K-ATPase is markedly upregulated in the cataractous lens.

59 atched, aged (16.1 +/- 8 pmol/mg) or nuclear cataractous lenses (49.0 +/- 26 pmol/mg).

60 A irradiation, pigmented proteins from human cataractous lenses also oxidized ASC.

61 were isolated from both normal (control) and cataractous lenses and assayed for cholesterol and phosp

62 idence that it is severely depleted in human cataractous lenses compared to age-matched controls, we

63 ritin H-chain and its distribution in canine cataractous lenses compared with noncataractous lenses.

64 chain was distributed differently throughout cataractous lenses compared with noncataractous lenses.

65 soluble proteins and was higher in a pool of cataractous lenses compared with normal aged lenses, rea

66 Ferritin from cataractous lenses contained more H-chain and bound 11-f

67 In cataractous lenses from eye bank eyes, cell density in t

68 racting crystalline deposits were present in cataractous lenses from two affected family members but

69 nd increase transparency in dissected rabbit cataractous lenses in vitro and cataract severity in viv

70 e loss of protein observed in human cortical cataractous lenses in vivo.

71 ndergone cataract surgery and epithelia from cataractous lenses of eye bank eyes were compared with e

72 erritin was comparable in noncataractous and cataractous lenses of similarly aged dogs.

73 projections of z-series from aged normal and cataractous lenses suggested that some of the stained li

74 weight complex obtained from young, old, and cataractous lenses suggesting potential interactions bet

75 roximately seven times greater in brunescent cataractous lenses than in aged noncataractous lenses.

76 Cataractous lenses were grouped into four classification

77 and C-terminal cleavage in selenite-induced cataractous lenses were identified.

78 Whole human cataractous lenses were obtained from donors after extra

79 rtical and nuclear regions of aged clear and cataractous lenses were obtained.

80 blocked all patterned visual input until the cataractous lenses were removed and the affected eyes fi

81 ound, the argpyrimidine levels in brunescent cataractous lenses were significantly higher (254.0 +/-

82 e dnajb1a morphants exhibited underdeveloped cataractous lenses with persistent apoptotic nuclei.

83 CML-rich proteins (immunoprecipitated from cataractous lenses) oxidized ascorbate approximately 4 t

84 he disulfide bonded gamma S-crystallins from cataractous lenses, supports this hypothesis.

85 e not continuous with LFC plasma membrane of cataractous lenses.

86 and cellular proliferation and migration in cataractous lenses.

87 t directly contribute to light-scattering in cataractous lenses.

88 ly the only treatment is surgical removal of cataractous lenses.

89 g, aged, nuclear cataractous, and brunescent cataractous lenses.

90 y significant differences between normal and cataractous lenses.

91 vels with no differences between control and cataractous lenses.

92 ly-significant cataract-visual acuity in the cataractous less than 20/40, and refractive error) based

93 ction analyses of the sterol-poor regions of cataractous membranes indicated increased membrane rigid

94 tectable amounts of light-density domains in cataractous membranes suggest either disruption of these

95 rable for sedimenting fractions of clear and cataractous membranes.

96 We identified a dominant cataractous mouse line (L1), caused by a missense alpha8

97 A dominant cataractous mouse line was identified from chemically in

98 -S11R mutant protein, was identified in this cataractous mouse line.

99 slit lamp screening, we identified two mouse cataractous mutant lines.

100 cortical membranes, was not observed in the cataractous nuclear membranes.

101 This size range corresponds well to MLBs in cataractous nuclei (average MLB radius, 1.4 microm) and,

102 close to the observed dimensions of MLBs in cataractous nuclei.

103 of young adult mouse lenses, these areas in cataractous old mouse lenses were found to contain accum

104 tly into the underlying cortex, resulting in cataractous opacities.

105 nescent lens proteins than in either nuclear cataractous or normal lenses.

106 Both normal and cataractous oriented membranes yielded meridional diffra

107 Lens fiber swelling and related cataractous outgrowth positively correlated to the degre

108 ffractive, are highly suited for working-age cataractous patients in terms of visual outcomes, readin

109 A uptake was markedly suppressed in diabetic cataractous rat lenses, which accumulated both the F-DHA

110 expression of the MT IIA gene in age-related cataractous relative to normal human lenses, suggesting

111 displayed lower levels of expression in the cataractous samples compared with that in the noncatarac

112 These were correlated with cataractous stages visually observed by slit lamp biomic

113 ded species are precursors to the aggregated cataractous states responsible for light scattering.

114 d Cu(II) binding was 20% to 30% increased in cataractous versus old and young lenses in WS (P < 0.01)

115 rkedly elevated in WS and WIS fractions from cataractous versus old or young crystallins (20% to seve

116 Control and cataractous whole lens membranes had C/P mole ratios of