ライフサイエンスコーパス: cathelicidin

1 D on related antibacterial proteins such as cathelicidin.

2 nd immature dermal fat that highly expressed cathelicidin.

3 nnate antimicrobial peptide LL-37, the human cathelicidin.

4 e magnitude of inflammation and increases in cathelicidin.

5 but it did not attenuate vitamin D3-induced cathelicidin.

6 FEV1% or in serial concentrations of plasma cathelicidin.

7 VDR and the downstream antimicrobial peptide cathelicidin.

8 , leading to VDR activation and induction of cathelicidin.

9 duction of antimicrobial peptides, including cathelicidin.

10 nst skin infection through the expression of cathelicidin.

11 zes with vitamin D to increase expression of cathelicidin.

12 atis because of a surge in the expression of cathelicidin.

13 icrobial function with antimicrobial peptide cathelicidin.

14 ted with AD and with decreased expression of cathelicidin.

15 function relationship of homologous primate cathelicidins.

16 g small interfering RNA (siRNA) specific for cathelicidin, 1,25D(3)-induced cathelicidin mRNA and pro

17 OCS1-3, TGF-beta1b), antimicrobial peptides (cathelicidin-1 and hepcidin), and the macrophage growth

18 Our results show that chicken cathelicidin-2 kills E. coli by permeabilizing the bacte

19 In this article, we show that chicken cathelicidin-2 kills Escherichia coli in an immunogenica

20 ease activity and differential processing of cathelicidin accompanied increased KLK expression.

21 Endothelial-bound cathelicidin activates formyl-peptide receptor 2 on clas

22 lts demonstrate that doxycycline can prevent cathelicidin activation, and suggest a previously unknow

23 However, little is known about how these cathelicidins affect TLR activation in the context of co

24 hanisms in the lung and the possible role of cathelicidin against different pulmonary pathogens in vi

25 In assay of cell binding to HA, cathelicidins also significantly inhibited this process,

26 the hCLD, LL-37, and the precursor form, pro-cathelicidin (also known as hCAP18), and we found that t

27 nals elicited by serum amyloid protein A and cathelicidins, among others.

28 tamin D3 (1,25D3)-induced gene expression of cathelicidin AMP in keratinocytes, suggesting a negative

29 act as a DAMP in the skin and how the human cathelicidin AMP LL-37 might influence growth factor pro

30 he interaction between tritrpticin (TRP3), a cathelicidin AMP, and micelles of different chemical com

31 glucocorticoids triggered the expression of cathelicidin, an antimicrobial critical for antimycobact

32 Cathelicidin, an antimicrobial host defence peptide, is

33 Antimicrobial peptides, such as cathelicidin and beta defensins, directly kill microbes

34 rate or trichostatin A) and 1,25D3 increased cathelicidin and CD14 expression and enhanced the antimi

35 ced expression of the antimicrobial peptides cathelicidin and DEFB4, being up-regulated by IFN-gamma,

36 Adjusted CVF cathelicidin and HNE concentrations (but not elafin) wer

37 The increased abundance and activity of cathelicidin and kallikrein 5 (KLK5), a predominant tryp

38 37 is generated upon proteolytic cleavage of cathelicidin and limits invading pathogens by directly t

39 concentrations of the antimicrobial peptide cathelicidin and recovery of lung function as assessed b

40 e antimicrobial peptides/proteins elafin and cathelicidin and sPTB.

41 found to be mediated in part by secretion of cathelicidin and was significantly increased by antibiot

42 ads to the vitamin D-dependent production of cathelicidin and, at the same time, an antimicrobial act

43 pregulation of macrophage NO, NADPH oxidase, cathelicidin, and autophagy mechanisms, but whether vita

44 M1 also binds murine cathelicidin, and its virulence contribution in a murine

45 NETs consisted of eDNA, histones, cathelicidin, and neutrophil elastase.

46 Protein concentrations of elafin and cathelicidin, and the enzyme human neutrophil elastase (

47 The cathelicidin antimicrobial peptide (Camp) gene was upreg

48 Cathelicidin antimicrobial peptide (CAMP) is a naturally

49 r Typhi and S. Typhimurium will induce human cathelicidin antimicrobial peptide (CAMP) production, an

50 (S1P), regulates production of a major AMP, cathelicidin antimicrobial peptide (CAMP), in response t

51 The innate immune element, cathelicidin antimicrobial peptide (CAMP), is vital in t

52 of the multifunctional antimicrobial peptide cathelicidin antimicrobial peptide (CAMP).

53 lls to produce an innate immune element, the cathelicidin antimicrobial peptide (CAMP).

54 or (VDR)-dependent mechanisms regulate human cathelicidin antimicrobial peptide (CAMP)/LL-37 in vario

55 )D) enhances innate immunity by inducing the cathelicidin antimicrobial peptide (hCAP).

56 ction was mediated through the production of cathelicidin antimicrobial peptide from adipocytes becau

57 These include the cathelicidin antimicrobial peptide gene and the TLR core

58 ifferentiating into adipocytes and producing cathelicidin antimicrobial peptide in response to Staphy

59 triking bactericidal interactions with human cathelicidin antimicrobial peptide LL-37, a frontline co

60 let-derived antimicrobials in serum, and the cathelicidin antimicrobial peptide LL-37.

61 ly localizes with elevated expression of the cathelicidin antimicrobial peptide LL-37.

62 deI and ompD are important for resistance to cathelicidin antimicrobial peptide, a mouse AMP produced

63 esponding to residues 7-27 of the only human cathelicidin antimicrobial peptide, LL37, is shown to ex

64 Using MCs derived from mice deficient in cathelicidin antimicrobial peptide, we showed that antim

65 Cathelicidin antimicrobial peptides are present at sites

66 These observations provide evidence that cathelicidin antimicrobial peptides mediate an anti-infl

67 mycin, the susceptibility of the bacteria to cathelicidin antimicrobial peptides or serum complement

68 Mast cells (MC) express cathelicidin antimicrobial peptides that act as broad-sp

69 tibility to reactive oxygen species and host cathelicidin antimicrobial peptides, which correlated wi

70 ability of PilB to mediate GBS resistance to cathelicidin antimicrobial peptides.

71 ate immune responses, such as the release of cathelicidin antimicrobial peptides.

72 heterodimer [S100A8/A9]) in the cytosol and cathelicidin antimicrobial protein (CAMP) in endosomes.

73 C/EBP-epsilon protein and lactoferrin (Ltf), cathelicidin antimicrobial protein (Camp), and lipocalin

74 ricidal effects, whereas the human and mouse cathelicidins appeared to mediate protection through inc

75 As many functions of cathelicidin are mediated through formyl peptide recepto

76 Cathelicidins are a family of bacteriocidal polypeptides

77 Cathelicidins are a family of cationic peptides expresse

78 Cathelicidins are a family of endogenous antimicrobial p

79 Cathelicidins are a gene family best known for their ant

80 These data lead us to propose that cathelicidins are a key, nonredundant component of host

81 ides such as human beta-defensins (hBDs) and cathelicidins are critical for protection against infect

82 Cathelicidins are essential in the protection against in

83 Cathelicidins are host defense peptides, expressed in th

84 Although cathelicidins are known to modulate activation by severa

85 peptides (AMPs), such as beta-defensins and cathelicidins, are essential components of innate and ad

86 nd/or IFN-gamma, which promotes induction of cathelicidin, as well as antimycobacterial activity, wer

87 nosine triphosphatases and the antimicrobial cathelicidin, assemble into complex clusters on LDs.

88 cantly associated with greater increments in cathelicidin at days 1 and 3 (p=0.04 and 0.004, respecti

89 olecalciferol induces the secretion of human cathelicidin, at the concentrations produced in vitro, c

90 ct response, whereas local administration of cathelicidin before sensitization inhibited the allergic

91 Host-defense molecules, cathelicidin, beta-defensin, and S100A8/A9, were also up

92 In vitro, cathelicidin bound directly to staphylokinase and augmen

93 r, we provide evidence that the induction of cathelicidin by glucocorticoids is not sufficient for ma

94 n part on the balance between degradation of cathelicidins by amebic released cysteine proteinases an

95 al and nucleic acid-complexing properties of cathelicidins can mediate pDC activation-promoting adapt

96 Antimicrobial peptides such as cathelicidins can modulate inflammation by interfering w

97 Our results show that chicken cathelicidin (CATH)-2 strongly enhances DNA-induced acti

98 , we examined the contribution of the murine cathelicidin, cathelicidin-related antimicrobial peptide

99 murine beta-defensin 3 (mBD3), mBD4, and the cathelicidin cathelin-related antimicrobial peptide (CRA

100 pimecrolimus enhances distinct expression of cathelicidin, CD14, and human beta-defensin-2 and beta-d

101 ailability prevented TGF-beta1 from inducing cathelicidin, CD14, or TLR2 in human keratinocytes, whil

102 quences from native helical families such as cathelicidins, cecropins, and magainins we demonstrate t

103 We show that cathelicidin concentrates in Lamp1 positive compartments

104 urve (AUC) of 0.75 (95% CI 0.68 to 0.81) for cathelicidin concentration at 14 to 15(+6) weeks.

105 lity, serial lung function, or serial plasma cathelicidin concentrations.

106 Cathelicidins constitute potent antimicrobial peptides c

107 f the role of the neutrophil granule protein cathelicidin (CRAMP in mouse, LL37 in human) in atherosc

108 ted with MC derived from either wild-type or cathelicidin-deficient (Camp(-/-)) mice and challenged w

109 Cathelicidin-deficient (Camp(-/-)) mice are less suscept

110 ing Pseudomonas aeruginosa (PA) keratitis in cathelicidin-deficient (KO) mice.

111 Cathelicidin-deficient mice exhibited an increased susce

112 Correspondingly, colonic mucosa of cathelicidin-deficient mice exhibited reduced expression

113 Camp(-/-) mice lacking cathelicidin demonstrated a large increase in ear swelli

114 effect on the antibacterial activity of the cathelicidin-derived antibacterial peptide LL37.

115 addition to its antibacterial activity, the cathelicidin-derived LL-37 peptide induces multiple immu

116 LL-37 is the only cathelicidin-derived polypeptide found in humans.

117 able E. coli In total, this study shows that cathelicidins do not affect immune activation by viable

118 However, mouse cathelicidin does influence recognition of CpG as bone m

119 in, at the concentrations produced in vitro, cathelicidin does not trigger autophagy.

120 ia were more susceptible to human and murine cathelicidins due to increased binding by these peptides

121 and viral infections through the release of cathelicidin during degranulation.

122 othesized that staphylokinase interacts with cathelicidin during the early pathogenesis of S. aureus

123 Cathelicidin (encoded by Camp) is an antimicrobial pepti

124 MP [cathelin-related antimicrobial peptide]) cathelicidins, essential components of the mammalian inn

125 Mice lacking the antimicrobial peptide cathelicidin experienced less severe infection than wild

126 Taken together, these data indicate that cathelicidin expressed from myeloid cells promotes CS-in

127 f this study was to characterize the role of cathelicidin expressed in non-tumorous cells in a precli

128 We also show that the proportion of cathelicidin expressing cells in the myometrium is highe

129 HAT activity was important to keratinocyte cathelicidin expression as the combination of histone de

130 The regulation of cathelicidin expression involves myeloid p65/RelA and so

131 Here we demonstrate that cathelicidin expression is increased at RNA and protein

132 In this study, we hypothesize that cathelicidin expression is induced in MCs by the activat

133 Cathelicidin expression localized to mucosal macrophages

134 due to upregulation of vitamin D3-responsive cathelicidin expression through the TLR2-dependent p38-M

135 ntimicrobial peptide from adipocytes because cathelicidin expression was decreased by inhibition of a

136 gnificantly lower numbers of CD1a+ cells and cathelicidin expression were noted as compared to CS-nai

137 nses such as reactive oxygen species and the cathelicidin family of antimicrobial peptides.

138 -3 (OV-3), an alpha-helical peptide from the cathelicidin family, demonstrating an increased antimicr

139 e LL-37/hCAP18, the only human member of the cathelicidin family, plays important roles in killing va

140 -spectrum human antimicrobial peptide in the cathelicidin family.

141 Cathelicidins form a family of small host defense peptid

142 in mast cells in response to the proteolytic cathelicidin fragment LL37 in a murine rosacea model and

143 The cathelicidin fragments however, did maintain their antim

144 n silico dissection of crotalicidin (Ctn), a cathelicidin from a South American pit viper, yielded fr

145 Expression of cathelicidin from bone marrow-derived immune cells regul

146 Deletion of the murine cathelicidin gene Cnlp enhanced an allergic contact resp

147 with high efficiency an exogenous alligator cathelicidin gene into a targeted non-coding region of c

148 Despite upregulating cathelicidin, glucocorticoids failed to promote macropha

149 These results suggest that cathelicidin has anti-inflammatory activity in skin that

150 Cathelicidin has dual functions in the skin, acting as a

151 ver, to date vitamin D-induced production of cathelicidin has not been shown to have an effect on the

152 Together, these data suggest that cathelicidin has roles in mediating pro-inflammatory res

153 LL-37, the only human cathelicidin, has been implicated in tumorigenesis, but

154 hort cationic antimicrobial peptides, called cathelicidins, have previously been shown to modulate TL

155 to ROS and were unable to process endogenous cathelicidin hCAP-18 into the antibacterial peptide LL-3

156 ions (n = 39, 25.66%) and included vimentin, cathelicidins, histones, S100 and neutrophil granule pro

157 Here, we show that neutrophil-derived cathelicidins (human: LL37, mouse: CRAMP) induce adhesio

158 e protected from spore-induced death by each cathelicidin in a time- and dose-dependent manner.

159 DNA to wild-type mice induced expression of cathelicidin in colons of control mice and mice with DSS

160 We examined whether macrophages express cathelicidin in colons of mice with experimental colitis

161 these results indicate that the functions of cathelicidin in control of TLR9 activation may include b

162 derstood, we investigated the requirement of cathelicidin in controlling transplantable tumors in mic

163 2 increases the production and expression of cathelicidin in mast cells, thereby enhancing their capa

164 Increased expression of cathelicidin in monocytes and experimental models of col

165 can be an indication of the localization of cathelicidin in neutrophils and macrophage granules as a

166 emonstrate a previously unrecognized role of cathelicidin in NK cell antitumor function.

167 nt data have suggested contrasting roles for cathelicidin in tumor development.

168 eine proteinase 1 (EhCP1), induce intestinal cathelicidins in human intestinal epithelial cell lines

169 ese observations underline the importance of cathelicidins in sensing bacterial products and regulati

170 In addition, other cathelicidins, including human, mouse, pig, and dog cath

171 Expression of cathelicidin increased in the inflamed colonic mucosa of

172 ncrements were associated with early greater cathelicidin increases, suggesting a possible mechanism

173 Furthermore, endogenous murine cathelicidin, induced by infection, has a fundamental ro

174 Cathelicidin inhibited HA induced MIP-2 release from mou

175 coupled or EGF-R signaling, both targets of cathelicidin inhibited HA-induced MIP-2 release.

176 o analyses showed that human, mouse, and pig cathelicidins inhibited Bacillus anthracis bacterial gro

177 we demonstrate that MCs are key mediators of cathelicidin-initiated skin inflammation.

178 ry and B cell-stimulating factors, including cathelicidin, interleukin 1 (IL-1), IL-4 and B cell-acti

179 Cathelicidin is a proposed defender against infection of

180 Cathelicidin is possibly involved in the regulation of t

181 These data demonstrate that cathelicidin is required for the 1,25D(3)-triggered anti

182 Degradation of intestinal cathelicidins is a novel function of E. histolytica cyst

183 but was found to be increased in the skin of cathelicidin knockout and ovalbumin-sensitized filaggrin

184 is finding was demonstrated by the fact that cathelicidin knockout mice (Camp(-/-)) permitted faster

185 ineffective in Camp-/- mice, revealing that cathelicidins largely mediate the efficacy of therapeuti

186 infants had higher eosinophil counts, higher cathelicidin levels, and increased proportions of Haemop

187 nd functional characteristics with mammalian cathelicidin-like host defense peptides (HDPs), we propo

188 defense molecule belonging to the family of cathelicidin-like proteins (gb|ADZ24001.1), is in fact a

189 MCs are also one of the primary sources of cathelicidin LL-37 (Cath LL-37), an antimicrobial peptid

190 owth factor (cutoff value, 42.92 pg/mL), and cathelicidin LL-37 (cutoff value, 3221.01 pg/mL) is pres

191 only to protamine but also to alpha-helical cathelicidin LL-37 and beta-sheet defensin human neutrop

192 d to investigate the influence of smoking on cathelicidin LL-37 and human neutrophil peptides 1 throu

193 obial and immunomodulatory polypeptide human cathelicidin LL-37 binds IAPP with nanomolar affinity an

194 We propose that the human cathelicidin LL-37 has the paradoxical effect of stimula

195 The human cathelicidin LL-37 is a multifunctional host defense pep

196 MP, and beta-defensin RBD-1; (iii) the human cathelicidin LL-37 killed KIM6 cells as well as rBALF di

197 significantly increased resistance to human cathelicidin LL-37 killing and daptomycin MIC creep comp

198 this article, we demonstrate that the human cathelicidin LL-37 mediates an antiviral effect on RSV b

199 Cathelicidin LL-37 plays an essential role in innate imm

200 mponent of the innate immunity system, human cathelicidin LL-37 plays an essential role in protecting

201 The human cathelicidin LL-37 serves a critical role in the innate

202 nt, SapA, was somewhat more sensitive to the cathelicidin LL-37 than the parent strain and was partia

203 In fact, the only human cathelicidin LL-37 triggers rapid sensing of nucleic aci

204 arkable increases in hBD-1, hBD-3, and human cathelicidin LL-37 were not observed.

205 tralize the antichlamydial activity of human cathelicidin LL-37, a host antimicrobial peptide secrete

206 ncountered during human infection, including cathelicidin LL-37, alpha-defensins, and beta-defensins.

207 f antimicrobials such as beta-defensins, the cathelicidin LL-37, cytokeratin-derived antimicrobial pe

208 wed that human beta-defensins 2 and 3, human cathelicidin LL-37, human neutrophil protein 1, and meli

209 uman beta-defensin-2, human beta-defensin-3, cathelicidin LL-37, psoriasin) and cytokines (TSLP, IL-2

210 uce peptides, such as beta-defensins and the cathelicidin LL-37, that are both antimicrobial and that

211 ing alpha-defensins, beta-defensins, and the cathelicidin LL-37.

212 ensins, ELR-negative CXC chemokines, and the cathelicidin LL-37.

213 Antimicrobial peptides, such as the cathelicidin LL-37/hCAP-18 and its mouse homolog catheli

214 eg5,7Ac2 or Kdn, conferred resistance to the cathelicidins LL-37 (human) and mouse cathelicidin-relat

215 min D metabolites regulate the expression of cathelicidin (LL-37), which is an endogenous antimicrobi

216 des (human beta-defensin [hBD]-2 and -3, and cathelicidin [LL-37]) are studied in an organotypic dent

217 eptide (CRAMP; an ortholog of the sole human cathelicidin, LL-37), were infected transurethrally with

218 sis where the defensins and the single human cathelicidin, LL-37, may contribute to disease.

219 The cleavage product of cathelicidin, LL-37, was assayed by ELISA.

220 re of the human CLD (hCLD) of the sole human cathelicidin, LL-37.

221 cterized antimicrobial activity is the human cathelicidin, LL-37.

222 as well as through direct pDC activation by cathelicidin (LL37).

223 ies to NETs as well as the ortholog of human cathelicidin/LL37 (CRAMP), a molecule externalized in th

224 ese differences were due to MC expression of cathelicidin, MC-deficient mice were reconstituted with

225 In addition, through their production of cathelicidin, MCs have the capacity to oppose invading p

226 Induction of cathelicidin-mediated antimicrobial pathway against intr

227 These findings suggest that cathelicidins might be utilized to augment the initial i

228 specific for cathelicidin, 1,25D(3)-induced cathelicidin mRNA and protein expressions were efficient

229 Secondary outcomes included leukocyte cathelicidin mRNA expression, plasma cytokine levels (IL

230 The relative expression level for cathelicidin mRNA was elevated in both the involved and

231 ed degranulation, secretion of antimicrobial cathelicidins, neutrophil recruitment, or provision of e

232 ng potent antimicrobial functions of porcine cathelicidins, nothing is known about their ability to p

233 In this study, we explored the effects of cathelicidins on DNA-induced activation of chicken macro

234 Calcitriol-treated patients had higher cathelicidin (P = 0.04) and IL-10 (P = 0.03) mRNA expres

235 study, we demonstrate that the murine mature cathelicidin peptide (CRAMP), encoded by the mouse gene

236 y and antibacterial activities of Hc-cath, a cathelicidin peptide derived from the venom of the sea s

237 The human cathelicidin peptide LL-37 enhances recognition of nucle

238 e conditions inhibited the generation of the cathelicidin peptide LL-37 from its precursor protein hC

239 ry concentrations of the human antimicrobial cathelicidin peptide LL-37 stimulate expression of the G

240 mass spectrometry (SELDI-TOF-MS) analysis of cathelicidin peptide purified from mast cells defined th

241 Human LL-37 is a multifunctional cathelicidin peptide that has shown a wide spectrum of a

242 diated in part by the expression of a unique cathelicidin peptide.

243 In mice, injection of the cathelicidin peptides found in rosacea, addition of SCTE

244 Cathelicidin peptides, which facilitate immune recogniti

245 line through inhibiting generation of active cathelicidin peptides.

246 Among the porcine cathelicidins, phylogenetic analysis of the C-terminal m

247 multifunctional host-defence peptides (HDPs) cathelicidins play crucial roles in inflammation.

248 The highest positively charged cathelicidin, PMAP-36, was found to be the most potent p

249 M1 protein also binds the cathelicidin precursor hCAP-18, preventing its proteolyt

250 ein 7 (KLK7) control enzymatic processing of cathelicidin precursor in the skin and regulate the even

251 to better understand how these may influence cathelicidin processing and function.

252 l that HIF-1alpha regulation of keratinocyte cathelicidin production is critical to their antibacteri

253 l extracellular traps, and kill bacteria via cathelicidin production.

254 In this location cathelicidins promote adhesion of classical monocytes an

255 Cathelicidins promote atherosclerosis by enhancement of

256 vels of thymic stromal lymphopoietin (TSLP), cathelicidin, proteases, that is, the kallikreins (KLK)-

257 Cathelicidin protects against induction of colitis in mi

258 y to release antimicrobial peptides, such as cathelicidin, protects against bacterial infections when

259 milar to the structure of the CLD of the pig cathelicidin, protegrin-3.

260 The primary outcome was plasma cathelicidin protein levels assessed 24 hours after stud

261 ) versus placebo (n = 31) had similar plasma cathelicidin protein levels at 24 hours (P = 0.16).

262 triol administration did not increase plasma cathelicidin protein levels in critically ill patients w

263 Therefore, cathelicidins provide a novel mechanism by which the imm

264 vivo evidence that endogenous expression of cathelicidin provides defense against corneal PA infecti

265 onic antimicrobial peptides (CAMPs), the rat cathelicidin rCRAMP, and beta-defensin RBD-1; (iii) the

266 elicidin LL-37/hCAP-18 and its mouse homolog cathelicidin-related antimicrobial peptide (CRAMP), are

267 the contribution of the murine cathelicidin, cathelicidin-related antimicrobial peptide (CRAMP), to i

268 o the antimicrobial peptides polymyxin B and cathelicidin-related antimicrobial peptide (CRAMP).

269 e probably through induced expression of the cathelicidin-related antimicrobial peptide and inducible

270 oeae concurrently with the downregulation of cathelicidin-related antimicrobial peptide and secretory

271 ociated with reduced local expression of the cathelicidin-related antimicrobial peptide as well as ev

272 was dramatically inhibited, by LL37 or mouse cathelicidin-related antimicrobial peptide in macrophage

273 to the cathelicidins LL-37 (human) and mouse cathelicidin-related antimicrobial peptide in vitro.

274 The expression of cytokines/chemokines and cathelicidin-related antimicrobial peptide was assessed

275 d corneas of adult B6, TLR5(-/-), Camp(-/-) (cathelicidin-related antimicrobial peptide), or PMN-depl

276 l microglia cells, induced the expression of cathelicidin-related antimicrobial peptide, and remarkab

277 nduced protection was partially abrogated in cathelicidin-related antimicrobial peptide-deficient mic

278 enes, most notably the antimicrobial peptide cathelicidin-related antimicrobial peptide.

279 Crotalicidin (Ctn), a cathelicidin-related peptide from the venom of a South A

280 nsin, human beta-defensin-3 (hBD-3), and the cathelicidin-related peptide, LL-37.

281 Consequently, cathelicidins represent an inducible target for preventa

282 Thus, cathelicidin resistance is essential for the pathogenesi

283 Absence of cathelicidin resulted in significantly delayed clearance

284 s the most closely related of the 11 porcine cathelicidins to human LL-37.

285 suggesting a negative regulatory function on cathelicidin transcription.

286 alpha- and -defensin-, magainin-, and cathelicidin-type antimicrobial peptides (AMPs) can kill

287 cytometric analysis showed that only the pig cathelicidin was capable of directly arresting vegetativ

288 use inhibition of sensitization by exogenous cathelicidin was dependent on the presence of functional

289 Protection afforded by the porcine cathelicidin was due to its bactericidal effects, wherea

290 Cathelicidin was initially identified as an antimicrobia

291 Cathelicidin was observed to be abundant in tumor-infilt

292 Colon expression of cathelicidin was significantly reduced in TLR9(-/-) mice

293 of the waaY mutant to other cationic helical cathelicidins was unaffected, indicating that particular

294 MCs deficient in cathelicidin were less efficient in killing vaccinia vir

295 sing dextran sulfate sodium (DSS); levels of cathelicidin were measured in human primary monocytes.

296 Cathelicidins were the most increased family, as confirm

297 t in expression of the antimicrobial peptide cathelicidin, which is required for 1,25D3 antimicrobial

298 [1,25(OH)2D] is important for production of cathelicidins, which in turn, are critical for antibacte

299 cidins, including human, mouse, pig, and dog cathelicidins, which lack antimicrobial activity under c

300 this study, we examined the interactions of cathelicidin with HA.