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1 ed potentials during hair cell deflection in cavefish.
2 ossible regulatory mechanism of Ppargamma in cavefish.
3 hk2 gene of naturally hyperglycemic Mexican cavefish.
4 s phagocytosis, are drastically decreased in cavefish.
5 to odors were different in surface fish and cavefish.
6 the rivers and two independently adapted of cavefish.
7 suppresses growth in surface fish but not in cavefish.
8 e level of right-oriented heart asymmetry in cavefish.
9 ibuted to the evolution of vestigial eyes in cavefish.
10 ssion is absent during somitogenesis of most cavefish.
11 triggering male sex determination in Pachon cavefish.
12 r of dorsal forerunner cells is increased in cavefish.
13 tiable appetite found in some populations of cavefish.
14 the origin of albinism in captive-bred Micos cavefish.
15 wo morphs: a seeing surface fish and a blind cavefish.
16 urred independently several times in Mexican cavefish.
17 c structures may lead to eye degeneration in cavefish.
18 c midline controls eye degeneration in blind cavefish.
19 al adipose tissue are drastically reduced in cavefish.
21 loss such as limbs in reptiles(4) or eyes in cavefish(5) frequently display a binary of presence/abse
23 gical conditions such as metabolic syndrome, cavefish also exhibit features not commonly associated w
27 t suggests that phylogenetically young Micos cavefish and phylogenetically old Pachon cave fish inher
28 layed a role in the evolution of eye loss in cavefish and provide the first evidence for HSP90 as a c
29 ences in the lateral line and vision between cavefish and surface fish and relate these differences t
31 Accordingly, reciprocal hybridization of cavefish and surface fish showed that modifications of h
32 ording in vivo from this neuron in the blind cavefish and two surface tetra (A. mexicanus and Astyana
34 ndscape factors related to the occurrence of cavefishes and cave crayfishes in the Ozark Highlands ec
36 s an additional adaptive feature of Astyanax cavefish, and demonstrates that coordinated changes betw
37 ng the resilience properties of A. mexicanus cavefish, and how they relate to environmental challenge
38 antagonist Dand5 is equalized or reversed in cavefish, and Shh increase in surface fish mimics change
39 between anatomical regions in surface fish, cavefish, and surface x cave F(2) hybrids, whose phenoty
42 the outer segments of the photoreceptors in cavefish are missing from the earliest stages examined.
45 ft in the overall immune cell composition in cavefish as the underlying cellular mechanism, indicatin
46 resolution brain atlas for the blind Mexican cavefish Astyanax mexicanus and coupled the atlas with a
47 ne circadian clock function in Mexican blind cavefish Astyanax mexicanus and its surface counterpart.
49 nction in the skeletal muscle of the Mexican Cavefish Astyanax mexicanus that is associated with redu
57 olfactory processing has rapidly evolved in cavefish at several levels: detection threshold, odor pr
58 ible genes provides a selective advantage to cavefish at the expense of a damped circadian oscillator
60 ce supporting the conclusion that the Pachon cavefish B is a "B-sex" chromosome that contains duplica
61 B-carrying male, we characterized the Pachon cavefish B sequence and found that it contains two dupli
62 We find that, although the metabolome of cavefish bears many similarities with pathological condi
65 es that independently evolved populations of cavefish can evolve the same behavioral traits to adapt
66 The appearance of albinism in captive Micos cavefish, caused by the same loss-of-function allele pre
67 tigates a set of captive, pigmented Astyanax cavefish collected from the Micos cave locality in 1970,
68 novo genome assembly for Astyanax mexicanus cavefish, contrast repeat elements to other teleost geno
73 eyed surface (surface fish) and blind cave (cavefish) dwelling forms in Astyanax also provides an at
78 c system induced social-like interactions in cavefish, even in unfamiliar environments, while reducin
79 te that changes in visceral asymmetry during cavefish evolution are influenced by maternal genetic ef
80 raits may be responsible for eye loss during cavefish evolution via pleiotropic function of the Shh s
82 n about how eyes and pigment are lost during cavefish evolution; namely, they have revealed some of t
83 setting, multiple independent populations of cavefish exhibit an altered feeding posture compared wit
93 spects of vision can be restored by crossing cavefish from different populations, suggesting that cha
94 ole as an MSD gene, we found that the Pachon cavefish gdf6b gene is expressed specifically in differe
96 1-Threonine 19, as a key component enhancing cavefish glycogen metabolism and sustained muscle contra
101 try is conventional in surface fish but some cavefish have evolved reversals in heart, liver, and pan
103 Thus, naturally occurring modifications in cavefish heart asymmetry are controlled by the effects o
104 versity in the cave ecosystem, and show that cavefish immune cells display a more sensitive pro-infla
105 me loss-of-function allele present in Pachon cavefish, implies that geographically and phylogenetical
107 ing acute UV exposure, surface fish, but not cavefish, increased sleep and activated the photoreactiv
108 nalysis of laboratory-reared and wild-caught cavefish indicated that this shift is driven by increase
109 makers for photoreceptors are present in the cavefish inner segments, the outer segments of the photo
115 nd higher expression of lipogenesis genes in cavefish livers when fed the same amount of food as surf
117 e-dwelling (surface fish) and cave-dwelling (cavefish) morphs of Astyanax mexicanus as a model for un
118 symmetry are present in hybrids derived from cavefish mothers but not from surface fish mothers.
119 come with a functional trade-off, decreasing cavefish muscle fiber shortening velocity, time to maxim
123 n a surface fish lens is transplanted into a cavefish optic cup, indicating that cavefish optic tissu
124 d into a cavefish optic cup, indicating that cavefish optic tissues have conserved the ability to res
126 the environmental conditions leading to the cavefish phenotype are known with certainty, and several
128 during restricted rations, only a subset of cavefish populations consume more food than their surfac
129 known with certainty, and several different cavefish populations have evolved constructive and regre
130 discovered that three independently derived cavefish populations have evolved persistent afferent ac
132 n to nutrient limitations.(4-9) We show that cavefish populations store large amounts of fat in diffe
134 de evaluation of deletion variability across cavefish populations to gain insight into this potential
135 ntributes to higher body fat accumulation in cavefish populations, an important adaptation to nutrien
137 river-dwelling surface fish and cave-adapted cavefish populations, to study the genetic adaptation to
141 ncing (ChIP-seq) showed that Ppargamma binds cavefish promoter regions of genes to a higher extent th
142 e sensory basis for behavioral adaptation in cavefish, providing insight into the process of nervous
144 ponse threshold in the lateral line of blind cavefish relative to surface fish leading to increased e
145 ng to note that the deficiencies in Astyanax cavefish resemble retinal diseases, such as retinitis pi
146 at cell proliferation continues in the adult cavefish retina but the newly born cells are removed by
148 into the innate and adaptive immune systems, cavefish shifted immune investment to the adaptive immun
150 th aging in surface fish remain unchanged in cavefish, suggesting altered regulation of aging-related
151 alysis of hybrids between surface and Pachon cavefish suggests that only a small number of loci with
152 tions confirmed diminished DDR and repair in cavefish, supporting an attenuated acute DNA damage resp
153 of negatively correlated activity within the cavefish tectum, suggesting positively correlated neural
154 the hpdb gene harbors a genomic deletion in cavefish that abolishes IRF2 repressor binding and derep
156 s are constitutively upregulated in normoxic cavefish to similar levels as in hypoxic surface fish.
157 face fish, suggesting an improved ability of cavefish to use lipogenesis to convert available energy
158 rm (surface fish) and many blind cave forms (cavefish), to study the evolution of eye degeneration.
161 to an increased cell area of erythrocytes in cavefish, we reason that they contain more hemoglobin pe
163 cides with a more sensitive immune system in cavefish, which is accompanied by a reduction in the imm
164 ith normal left-oriented heart asymmetry and cavefish with high levels of reversed right-oriented hea
165 independently evolved populations of albino cavefish with naturally occurring mutations in oca2.