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1 ed potentials during hair cell deflection in cavefish.
2 ossible regulatory mechanism of Ppargamma in cavefish.
3  hk2 gene of naturally hyperglycemic Mexican cavefish.
4 s phagocytosis, are drastically decreased in cavefish.
5  to odors were different in surface fish and cavefish.
6  the rivers and two independently adapted of cavefish.
7 suppresses growth in surface fish but not in cavefish.
8 e level of right-oriented heart asymmetry in cavefish.
9 ibuted to the evolution of vestigial eyes in cavefish.
10 ssion is absent during somitogenesis of most cavefish.
11  triggering male sex determination in Pachon cavefish.
12 r of dorsal forerunner cells is increased in cavefish.
13 tiable appetite found in some populations of cavefish.
14 the origin of albinism in captive-bred Micos cavefish.
15 wo morphs: a seeing surface fish and a blind cavefish.
16 urred independently several times in Mexican cavefish.
17 c structures may lead to eye degeneration in cavefish.
18 c midline controls eye degeneration in blind cavefish.
19 al adipose tissue are drastically reduced in cavefish.
20 fish) and various blind cave-dwelling forms (cavefish) [2-4].
21 loss such as limbs in reptiles(4) or eyes in cavefish(5) frequently display a binary of presence/abse
22 lines, which reflect key metabolic traits of cavefish adaptation.
23 gical conditions such as metabolic syndrome, cavefish also exhibit features not commonly associated w
24 as elevated in the oral-pharyngeal region in cavefish and later was confined to taste buds.
25  for transgenesis applications in zebrafish, cavefish and other models.
26                                           In cavefish and other species, mutations in oculocutaneous
27 t suggests that phylogenetically young Micos cavefish and phylogenetically old Pachon cave fish inher
28 layed a role in the evolution of eye loss in cavefish and provide the first evidence for HSP90 as a c
29 ences in the lateral line and vision between cavefish and surface fish and relate these differences t
30                      Genetic crosses between cavefish and surface fish revealed an inverse relationsh
31     Accordingly, reciprocal hybridization of cavefish and surface fish showed that modifications of h
32 ording in vivo from this neuron in the blind cavefish and two surface tetra (A. mexicanus and Astyana
33                                   We sampled cavefishes and cave crayfishes at 61 sampling units usin
34 ndscape factors related to the occurrence of cavefishes and cave crayfishes in the Ozark Highlands ec
35                                         Both cavefishes and cave crayfishes were more likely to occur
36 s an additional adaptive feature of Astyanax cavefish, and demonstrates that coordinated changes betw
37 ng the resilience properties of A. mexicanus cavefish, and how they relate to environmental challenge
38 antagonist Dand5 is equalized or reversed in cavefish, and Shh increase in surface fish mimics change
39  between anatomical regions in surface fish, cavefish, and surface x cave F(2) hybrids, whose phenoty
40                 From a molecular standpoint, cavefish appear as if they experience 'constant light' r
41                                     However, cavefish appear to avoid pathologies typically associate
42  the outer segments of the photoreceptors in cavefish are missing from the earliest stages examined.
43                          We found that adult cavefish are potent predators that readily attack smalle
44 oach, supported by learning data, uses blind cavefish as an example.
45 ft in the overall immune cell composition in cavefish as the underlying cellular mechanism, indicatin
46 resolution brain atlas for the blind Mexican cavefish Astyanax mexicanus and coupled the atlas with a
47 ne circadian clock function in Mexican blind cavefish Astyanax mexicanus and its surface counterpart.
48                                    The blind cavefish Astyanax mexicanus is known to be asocial.
49 nction in the skeletal muscle of the Mexican Cavefish Astyanax mexicanus that is associated with redu
50                One such example, the Mexican cavefish Astyanax mexicanus, has lost moderate-to-vigoro
51 size variation in surface populations of the cavefish Astyanax mexicanus.
52 te buds) at the expense of eyes in the blind cavefish Astyanax mexicanus.
53 ific pineal gland expression in the eye-less cavefish (Astyanax).
54                                  The Mexican cavefish, Astyanax mexicanus, consists of eyed river-dwe
55                     Here, we use the Mexican cavefish, Astyanax mexicanus, to study the genetic basis
56 pendently derived populations of the Mexican cavefish, Astyanax mexicanus.
57  olfactory processing has rapidly evolved in cavefish at several levels: detection threshold, odor pr
58 ible genes provides a selective advantage to cavefish at the expense of a damped circadian oscillator
59 ncreases oral and taste bud amplification in cavefish at the expense of eyes.
60 ce supporting the conclusion that the Pachon cavefish B is a "B-sex" chromosome that contains duplica
61 B-carrying male, we characterized the Pachon cavefish B sequence and found that it contains two dupli
62     We find that, although the metabolome of cavefish bears many similarities with pathological condi
63 ssion of dkk1b) that may have contributed to cavefish brain evolution.
64                    We also show that Mexican cavefish can be intubated and imaged in the same way, de
65 es that independently evolved populations of cavefish can evolve the same behavioral traits to adapt
66  The appearance of albinism in captive Micos cavefish, caused by the same loss-of-function allele pre
67 tigates a set of captive, pigmented Astyanax cavefish collected from the Micos cave locality in 1970,
68  novo genome assembly for Astyanax mexicanus cavefish, contrast repeat elements to other teleost geno
69                             We conclude that cavefish cope with hypoxia by increasing erythrocyte dev
70                  Here we show that the blind cavefish Cryptotora thamicola walks and climbs waterfall
71 h increase in surface fish mimics changes in cavefish dand5 asymmetry.
72                                Despite this, cavefish displayed a striking degree of muscular enduran
73  eyed surface (surface fish) and blind cave (cavefish) dwelling forms in Astyanax also provides an at
74        Small eye primordia are formed during cavefish embryogenesis, which later arrest in developmen
75                                              Cavefish embryos initially develop eyes, but they subseq
76 ns and laminated retina initially develop in cavefish embryos, but the lens dies by apoptosis.
77                                           In cavefish embryos, eye primordia degenerate under the inf
78 c system induced social-like interactions in cavefish, even in unfamiliar environments, while reducin
79 te that changes in visceral asymmetry during cavefish evolution are influenced by maternal genetic ef
80 raits may be responsible for eye loss during cavefish evolution via pleiotropic function of the Shh s
81 e impacted morphological brain change during cavefish evolution.
82 n about how eyes and pigment are lost during cavefish evolution; namely, they have revealed some of t
83 setting, multiple independent populations of cavefish exhibit an altered feeding posture compared wit
84                                              Cavefish exhibited elevated gammaH2AX in the brain and i
85                         Here, we reveal that cavefish exhibited social-like interactions in familiar
86       Together, these findings indicate that cavefish experience elevated cellular hallmarks of sleep
87 hat Pax6 may be one of the genes controlling cavefish eye degeneration.
88 he role of hh signalling in the evolution of cavefish eye regression.
89 pensate for loss of vision and to help blind cavefish find food in darkness.
90 e-dwelling (surface fish) and cave-dwelling (cavefish) forms of Astyanax.
91 e-dwelling (surface fish) and cave-dwelling (cavefish) forms.
92 ling (surface fish) and blind cave-dwelling (cavefish) forms.
93 spects of vision can be restored by crossing cavefish from different populations, suggesting that cha
94 ole as an MSD gene, we found that the Pachon cavefish gdf6b gene is expressed specifically in differe
95                                We expect the cavefish genome to advance understanding of the evolutio
96 1-Threonine 19, as a key component enhancing cavefish glycogen metabolism and sustained muscle contra
97              We discovered that albino Micos cavefish harbor two copies of a loss-of-function ocular
98       These findings support the notion that cavefish have adapted to hypoxia in caves through modula
99                                              Cavefish have enlarged both hematopoietic domains and de
100           To survive under these conditions, cavefish have evolved a range of adaptations, including
101 try is conventional in surface fish but some cavefish have evolved reversals in heart, liver, and pan
102                                              Cavefishes have long been used as model organisms showca
103   Thus, naturally occurring modifications in cavefish heart asymmetry are controlled by the effects o
104 versity in the cave ecosystem, and show that cavefish immune cells display a more sensitive pro-infla
105 me loss-of-function allele present in Pachon cavefish, implies that geographically and phylogenetical
106 increased levels of light-inducible genes in cavefish, including clock repressor per2.
107 ing acute UV exposure, surface fish, but not cavefish, increased sleep and activated the photoreactiv
108 nalysis of laboratory-reared and wild-caught cavefish indicated that this shift is driven by increase
109 makers for photoreceptors are present in the cavefish inner segments, the outer segments of the photo
110                                              Cavefish is therefore an outstanding model to understand
111                               Although adult cavefish lack functional eyes, small eye primordia are f
112 fty signaling system are also present in the cavefish lateral plate mesoderm (LPM).
113                              Surface fish to cavefish lens transplantation, which restores retinal gr
114 rait loss and enhancement across independent cavefish lineages.
115 nd higher expression of lipogenesis genes in cavefish livers when fed the same amount of food as surf
116 ted at both transcript and protein levels in cavefish livers.
117 e-dwelling (surface fish) and cave-dwelling (cavefish) morphs of Astyanax mexicanus as a model for un
118 symmetry are present in hybrids derived from cavefish mothers but not from surface fish mothers.
119 come with a functional trade-off, decreasing cavefish muscle fiber shortening velocity, time to maxim
120              Neither lens transplantation in cavefish nor lens deletion in surface fish affected reti
121 ere was a weak positive relationship between cavefish occurrence and disturbance.
122 lanting a surface fish embryonic lens into a cavefish optic cup can restore a complete eye.
123 n a surface fish lens is transplanted into a cavefish optic cup, indicating that cavefish optic tissu
124 d into a cavefish optic cup, indicating that cavefish optic tissues have conserved the ability to res
125                  Here, in Astyanax mexicanus cavefish originating from Pachon cave, we show that Bs a
126  the environmental conditions leading to the cavefish phenotype are known with certainty, and several
127 os induces asymmetric changes resembling the cavefish phenotype.
128  during restricted rations, only a subset of cavefish populations consume more food than their surfac
129  known with certainty, and several different cavefish populations have evolved constructive and regre
130  discovered that three independently derived cavefish populations have evolved persistent afferent ac
131                                              Cavefish populations rely almost entirely on sporadic fo
132 n to nutrient limitations.(4-9) We show that cavefish populations store large amounts of fat in diffe
133                                 Although all cavefish populations tested lose weight more slowly than
134 de evaluation of deletion variability across cavefish populations to gain insight into this potential
135 ntributes to higher body fat accumulation in cavefish populations, an important adaptation to nutrien
136                                              Cavefish populations, Astyanax mexicanus (Teleostei: Cha
137 river-dwelling surface fish and cave-adapted cavefish populations, to study the genetic adaptation to
138 ome-wide comparison between surface fish and cavefish populations.
139 responsible for eye degeneration in multiple cavefish populations.
140 erior embryonic midline in several different cavefish populations.
141 ncing (ChIP-seq) showed that Ppargamma binds cavefish promoter regions of genes to a higher extent th
142 e sensory basis for behavioral adaptation in cavefish, providing insight into the process of nervous
143                    VAB was typically seen in cavefish, rarely in surface fish, and was advantageous f
144 ponse threshold in the lateral line of blind cavefish relative to surface fish leading to increased e
145 ng to note that the deficiencies in Astyanax cavefish resemble retinal diseases, such as retinitis pi
146 at cell proliferation continues in the adult cavefish retina but the newly born cells are removed by
147                                          The cavefish retina is subsequently disorganized, apoptotic
148 into the innate and adaptive immune systems, cavefish shifted immune investment to the adaptive immun
149                                  In concert, cavefish show amplified jaw size and taste bud numbers a
150 th aging in surface fish remain unchanged in cavefish, suggesting altered regulation of aging-related
151 alysis of hybrids between surface and Pachon cavefish suggests that only a small number of loci with
152 tions confirmed diminished DDR and repair in cavefish, supporting an attenuated acute DNA damage resp
153 of negatively correlated activity within the cavefish tectum, suggesting positively correlated neural
154  the hpdb gene harbors a genomic deletion in cavefish that abolishes IRF2 repressor binding and derep
155     These fish are born with eyes but in the cavefish, they degenerate during development.
156 s are constitutively upregulated in normoxic cavefish to similar levels as in hypoxic surface fish.
157 face fish, suggesting an improved ability of cavefish to use lipogenesis to convert available energy
158 rm (surface fish) and many blind cave forms (cavefish), to study the evolution of eye degeneration.
159                 It is known that the lens of cavefish undergoes apoptosis and that some cells in the
160                The mutated genes involved in cavefish vestigial eye formation have not been character
161 to an increased cell area of erythrocytes in cavefish, we reason that they contain more hemoglobin pe
162                               Interestingly, cavefish, which exhibit a disrupted central clock, exhib
163 cides with a more sensitive immune system in cavefish, which is accompanied by a reduction in the imm
164 ith normal left-oriented heart asymmetry and cavefish with high levels of reversed right-oriented hea
165  independently evolved populations of albino cavefish with naturally occurring mutations in oca2.

 
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