ライフサイエンスコーパス: cell antigen

1 bacteria is both a virulence factor and a B-cell antigen.

2 g (Jedi) T cells enable visualization of a T-cell antigen.

3 esponse to HtrABb, indicating that it is a B-cell antigen.

4 installation of a TLR2/6 agonist and a MAIT cell antigen.

5 eby activating immune responses against dead-cell antigens.

6 lenging to identify relevant peptide-based T cell antigens.

7 , Th1 reactivity spread from EGFP to other B-cell antigens.

8 nses to EGFP which did not spread to other B-cell antigens.

9 rable splenocyte and serum reactivity to B16 cell antigens.

10 ze endothelial, gastrointestinal, and immune-cell antigens.

11 litis), and autoantibodies specific for beta-cell antigens.

12 omparative gene expression profiling of stem cell antigen 1(-) (Sca1(-)) and Sca1(+) neonatal fibrobl

13 ngII signature proteins (bone marrow stromal cell antigen 1, glutamine synthetase [GLNA], laminin sub

14 on, Stat5 activation, and expression of stem cell antigen 1.

15 l cell population that was positive for stem cell antigen 1.

16 mol/umol of creatinine], bone marrow stromal cell antigen 1: 3.8 versus 3.0, P = 0.03; GLNA: 1.2 vers

17 the role of Toll-like receptor 4 (TLR4)/stem cell antigen-1 (Sca-1) signaling in this process, bacter

18 s in adult mouse myocardium all sharing stem cell antigen-1 (Sca1), based on side population (SP) phe

19 be documented by the down-regulation of stem cell antigen-1 and acquisition of responsiveness to gran

20 ny-forming unit progenitors coexpressed stem cell antigen-1 and CD45 and were adventitially located,

21 distinct from neighboring cells lacking stem cell antigen-1 or CD45 and contained a proliferative (Ki

22 ariable models revealed more blood dendritic cell antigen-1(+) (BDCA-1(+)) myeloid dendritic cells (m

23 expressed either SSEA-1(+) or Sca-1(+) (stem cell antigen-1).

24 ontained abundant stem cells expressing stem cell antigen-1, Wilms' tumor 1 (WT-1), and CD34, suggest

25 LSK (lineage-negative, stem cell antigen-1-positive, c-Kit-positive) cells were quan

26 cell (MSC) markers, including CD105 and stem-cell antigen-1.

27 (SPC)(+) alveolar type 2 cells and in Clara cell antigen 10 (CC10)(+) Clara cells by use of cell-typ

28 Blood dendritic cell antigen 2 (BDCA-2; also designated CLEC4C or CD303)

29 We tested bone marrow stromal cell antigen 2 (BST-2) gene variants rs3217318, a 19-bas

30 sm of the host restriction factor BM stromal cell antigen 2 (BST-2).

31 Bone marrow stromal cell antigen 2 (BST2) is a cellular restriction factor w

32 IFN-I-regulated ligand, bone marrow stromal cell antigen 2 (BST2) plays a key role in controlling th

33 ISGs), such as ISG15 and bone marrow stromal cell antigen 2 (BST2).

34 0-amino-acid autotransporter protein surface cell antigen 2 (Sca2) promotes actin polymerization on t

35 Sca2 (surface cell antigen 2) is the only bacterial protein known to p

36 ficant downregulation of bone marrow stromal cell antigen-2 (BST2), a potential therapeutic target, v

37 ransposon mutagenesis, we identified surface cell antigen 4 (Sca4) as a secreted effector of spread t

38 n (Ig) molecules that efficiently capture ss-cell antigens allows autoreactive B-lymphocytes bypassin

39 of the NAb targets gD and gB and the novel T cell antigen and tegument protein UL40, and we compared

40 f inflammatory T-cell responses to apoptotic cell antigens and failure of long-tolerance induction.

41 These data suggest that stem-cell antigens and PD-L1 may be targeted for immunopreven

42 Our knowledge of T cell antigens and their implications for human health is

43 eated a novel category of tumor-associated T-cell antigens based on their exclusive and frequent repr

44 meric antigen receptor (CAR) targeting the B cell antigen CD19 have yielded remarkable clinical respo

45 meric antigen receptor (CAR) targeting the B-cell antigen CD19.

46 hus, the spreading of autoreactivity among B-cell antigens corresponded with the transition from peri

47 tion of proteins mucin-5AC and prostate stem-cell antigen could identify high-grade dysplasia/cancer

48 unctions empowered by specific delivery of T cell antigens could be harnessed for tolerance induction

49 beta-Cell antigen delivered to DCIR2(+) DCs delayed diabetes

50 we describe the first report of a human mast cell antigen-dependent passive systemic anaphylaxis resp

51 in approaches to address the challenge of T cell antigen discovery.

52 These observations indicate that T cell antigen discrimination likely occurs by sensing the

53 alization-traits associated with increased B cell antigen drive.

54 d that pDCs accumulated at sites of CD8(+) T cell antigen-driven activation in a CCR5-dependent fashi

55 n epitope that is an immunodominant CD8(+) T cell antigen during primary infection of C57BL/6 mice wi

56 expand the number of documented HHV-6B CD4 T-cell antigens from approximately 11 to 60.

57 face receptors (CD19-22) to immunodominant T-cell antigens from EBV proteins, including EBNA1, EBNA3B

58 Knowledge of T-cell antigens has reached the genome-wide level for CMV

59 ient to initiate expression of smooth muscle cell antigens in ASC, only activin A IgG blocked the eff

60 physics, and functional assays to identify T-cell antigens in long-term survivors of pancreatic cance

61 The immunodominant CD4 T-cell antigens included both long proteins abundantly pre

62 The most powerful iNKT cell antigen is alpha-galactosylceramide (alpha-GalCer),

63 identified to be a dominant murine CD4(+) T cell antigen, its level of expression during the bacteri

64 Thus, MAIT cell antigen-mediated immunotherapy for M. tb.

65 Autoimmune responses to meiotic germ cell antigens (MGCA) that are expressed on sperm and tes

66 d with (124)I-labeled A11 anti-prostate stem cell antigen minibody.

67 g the expression of the neuroectodermal stem cell antigen, nestin, and up-regulating the glial matura

68 Intriguingly, CD4 T-cell antigens newly described in this report are among t

69 posing an epitope(s), probably the senescent cell antigen of band 3.

70 ns from 1:100 to 1:102,400 using crude whole-cell antigens of the Karp, Kato, and Gilliam strains of

71 entation of established myeloma-associated T-cell antigens on the HLA ligandome level, we found a sub

72 ET data of mice implanted with prostate stem cell antigen-overexpressing tumors and injected with (12

73 The timing and location of B cell antigen presentation during MS and its animal model

74 emerged as a critical regulator of dendritic cell antigen presentation, but its role in T-cell immuni

75 echanism of protection may involve lack of B cell antigen presentation, which impairs T-cell activati

76 oint of the GC reaction by promoting naive B cell antigen presentation.

77 during infection was necessary to alter host cell antigen presentation.

78 cyte to dendritic cell differentiation and T-cell antigen presentation.

79 A-4) deficiency abrogated EAE dependent on B cell antigen presentation.

80 en shown to induce activation of endothelial cells, antigen-presenting cells, and platelets, resultin

81 In the surviving cells, antigen-processing machinery component gene trans

82 -terminal cysteine of the anti-prostate stem cell antigen (PSCA) cys-diabody A2, and subsequently rad

83 Prostate stem cell antigen (PSCA) is expressed on the cell surface in

84 We report that the radial glial cell antigen RC2 identifies the majority of proliferatin

85 Examination of lymph node cell antigen recall responses identified elevated immune

86 Nfkb1(SSAA) mutation decreased B cell antigen receptor (BCR) activation of NF-kappaB in F

87 RK activity and CLL proliferation required B cell antigen receptor (BCR) activation, as inhibition of

88 B cell antigen receptor (BCR) and CD40 signaling are rewir

89 respond to antigens by engagement of their B-cell antigen receptor (BCR) and of coreceptors through w

90 es encoding the variable (V) region of the B-cell antigen receptor (BCR) are assembled from V, D (div

91 obial molecules, enhance signalling by the B-cell antigen receptor (BCR) by activating the actin-seve

92 Mature B cells coexpress both IgM and IgD B-cell antigen receptor (BCR) classes, which are organized

93 ry on their surface multiple copies of the B cell antigen receptor (BCR) comprising the membrane-boun

94 milar to resting mature B cells, where the B-cell antigen receptor (BCR) controls cellular survival,

95 B-cell antigen receptor (BCR) expression is a key feature

96 Binding of antigen to the B cell antigen receptor (BCR) initiates a multitude of eve

97 Affinity maturation of the B cell antigen receptor (BCR) is a conserved and crucial c

98 cytosolic Ca(2+) following ligation of the B cell antigen receptor (BCR) led to the assumption that t

99 The B cell antigen receptor (BCR) plays a central role in the

100 The establishment of a diverse B cell antigen receptor (BCR) repertoire by V(D)J recombin

101 Kinases downstream of B-cell antigen receptor (BCR) represent attractive targets

102 B cell activation is regulated by B cell antigen receptor (BCR) signaling and antigen intern

103 kinase (Erk) activation mediated by tonic B-cell antigen receptor (BCR) signaling and that this sign

104 Notch2 and B cell antigen receptor (BCR) signaling determine whether

105 ism of Lin28b action nor the importance of B cell antigen receptor (BCR) signaling in this process wa

106 B cell antigen receptor (BCR) signaling is critical for B

107 In B-lymphocytes, the down-regulation of B-cell antigen receptor (BCR) signaling is critical for su

108 egulating tonic, but not antigen-mediated, B-cell antigen receptor (BCR) signaling through modulation

109 are selected for an intermediate level of B-cell antigen receptor (BCR) signalling strength: attenua

110 B cell antigen receptor (BCR) signals induce Syk activatio

111 To explore the role of B cell antigen receptor (BCR) specificity in driving B1 ce

112 In addition, B cell antigen receptor (BCR) stereotypes as defined by IG

113 Nck bound directly to the B cell antigen receptor (BCR) via the non-immunoreceptor t

114 such as the T cell antigen receptor (TCR), B cell antigen receptor (BCR), and Fc receptors uses the s

115 kinase is essential for signaling from the B cell antigen receptor (BCR), and thus for antibody respo

116 IRF8 dampened signaling via the B cell antigen receptor (BCR), facilitated antigen-specifi

117 ell development requires expression of the B cell antigen receptor (BCR), it remains unclear whether

118 into cytoplasmic signaling events through B-cell antigen receptor (BCR)-based signalosomes at the B-

119 Over the past several decades, B cell antigen receptor (BCR)-induced signaling pathways h

120 on compromises the activity of the pivotal B-cell antigen receptor (BCR)-proximal effector spleen tyr

121 ignaling pathways, some emanating from the B-cell antigen receptor (BCR).

122 Furthermore, gammadelta T cell antigen receptor (gammadeltaTCR) signal strength tu

123 In B lymphopoiesis, activation of the pre-B cell antigen receptor (pre-BCR) is associated with both

124 gnaling components of the precursor to the B cell antigen receptor (pre-BCR), including defects in BL

125 rough the pre-B stage triggered by the pre-B-cell antigen receptor (pre-BCR).

126 Signaling via the pre-T cell antigen receptor (pre-TCR) and the receptor Notch1

127 ) following suboptimal stimulation via the T cell antigen receptor (TCR) (induced T(reg) cells (iT(re

128 The locus encoding the T cell antigen receptor (TCR) alpha-chain and delta-chain

129 tions further differed in their use of the T cell antigen receptor (TCR) alpha-chain variable region

130 The interaction between the T cell antigen receptor (TCR) and antigenic peptide in com

131 rom naive precursors when signals from the T cell antigen receptor (TCR) and certain cytokine recepto

132 acted in synergy with stimulation via the T cell antigen receptor (TCR) and coreceptor CD28 to accel

133 T cells lost the signaling activity of the T cell antigen receptor (TCR) and expressed a protein comp

134 olecules associated with activation of the T cell antigen receptor (TCR) and of immunological-checkpo

135 The expression of Myc is regulated by the T cell antigen receptor (TCR) and pro-inflammatory cytokin

136 d directly with the signal strength of the T cell antigen receptor (TCR) and required the coreceptor

137 ganization of CD4, and its relationship to T-cell antigen receptor (TCR) and the active form of Src k

138 h ITAM multiplicity) in the complex of the T cell antigen receptor (TCR) and the invariant signaling

139 We found that clonotypes expressing the T cell antigen receptor (TCR) beta-chain variable region 1

140 osphatase PTPN22 limited signaling via the T cell antigen receptor (TCR) by weak agonists and self an

141 Variable strengths of signaling via the T cell antigen receptor (TCR) can produce divergent outcom

142 The T-cell antigen receptor (TCR) complex contains 10 copies o

143 amily kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex.

144 mplex (MHC) proteins are recognized by the T cell antigen receptor (TCR) dictates the homeostasis of

145 In the thymus, low-affinity T cell antigen receptor (TCR) engagement facilitates posit

146 T cell antigen receptor (TCR) engagement has been shown to

147 The interaction between the T cell antigen receptor (TCR) expressed by natural killer

148 ypes generally show simplified patterns of T cell antigen receptor (TCR) expression, rapid effector r

149 Crystal structures of a T cell antigen receptor (TCR) from a MAIT cell in complex

150 was strongly induced by activation of the T cell antigen receptor (TCR) in a pathway involving calci

151 nterleukin 17 (IL-17), but the role of the T cell antigen receptor (TCR) in this developmental proces

152 The T cell antigen receptor (TCR) is a multisubunit receptor o

153 The T-cell antigen receptor (TCR) is an assembly of eight type

154 Although heightened signaling via the T cell antigen receptor (TCR) is critical for the differen

155 Signaling via the T cell antigen receptor (TCR) is initiated by Src-family k

156 The self-reactivity of their T-cell antigen receptor (TCR) is thought to contribute to

157 The T cell antigen receptor (TCR) is unique in that its affini

158 The kinetic proofreading model can explain T cell antigen receptor (TCR) ligand discrimination; howev

159 requires interleukin 2 (IL-2) and agonist T cell antigen receptor (TCR) ligands and is controlled by

160 The semi-invariant MAIT T-cell antigen receptor (TCR) recognises riboflavin and fo

161 How the T cell antigen receptor (TCR) recognizes these cations bou

162 ocesses, but its role in signaling via the T cell antigen receptor (TCR) remains unknown.

163 Here we show that the T-cell antigen receptor (TCR) repertoire of intestinal TH1

164 RNA-seq for assessing T-cell clonality and T-cell antigen receptor (TCR) repertoire of the neoplastic

165 Herein we examine heterogeneity of the T cell antigen receptor (TCR) repertoire.

166 le-cell RNA sequencing and high-throughput T cell antigen receptor (TCR) sequencing to characterize t

167 Using deep T cell antigen receptor (TCR) sequencing, we found that th

168 tors and cell-intrinsic factors related to T cell antigen receptor (TCR) signal quantity and quality.

169 ng the nature of molecules involved in the T cell antigen receptor (TCR) signal transduction network,

170 ound that calcineurin was recruited to the T cell antigen receptor (TCR) signaling complex, where it

171 T cell antigen receptor (TCR) signaling drives distinct re

172 CD8(+) T cells in the thymus requires that T cell antigen receptor (TCR) signaling end in time for cy

173 immunity and requires a limited degree of T cell antigen receptor (TCR) signaling in response to sel

174 T cell antigen receptor (TCR) signaling in the thymus init

175 T-cell antigen receptor (TCR) signaling is essential for a

176 -reactivity, with a particular emphasis on T cell antigen receptor (TCR) signaling thresholds.

177 catalytic activity of Zap70 is crucial for T cell antigen receptor (TCR) signaling, but the quantitat

178 nd WASP-interacting-protein (WIP) regulate T cell antigen receptor (TCR) signaling, but their role in

179 To investigate how Csk activity regulates T cell antigen receptor (TCR) signaling, we utilized a mou

180 We used Nur77-a marker of T cell antigen receptor (TCR) signaling-to identify antige

181 ctivator of the RAS-MAPK pathway following T cell antigen receptor (TCR) signaling.

182 We found that, upon T cell antigen receptor (TCR) stimulation, T cells upregul

183 Mutations in T-cell antigen receptor (TCR) subunit genes cause rare imm

184 sensor of thresholds for signaling via the T cell antigen receptor (TCR) that was essential for T cel

185 The ability of a single T cell antigen receptor (TCR) to cross-react with multiple

186 ever, the mechanisms that allow the clonal T cell antigen receptor (TCR) to functionally engage multi

187 A and Foxp1D induced by stimulation of the T cell antigen receptor (TCR) to inhibit the generation of

188 nd the tyrosine phosphatase CD45 underpins T cell antigen receptor (TCR) triggering, but how such seg

189 T cell proliferation is initiated by T cell antigen receptor (TCR) triggering, soluble growth f

190 played enhanced proximal signaling via the T cell antigen receptor (TCR) without an effect on the act

191 ransduction by immunoreceptors such as the T cell antigen receptor (TCR), B cell antigen receptor (BC

192 ting THEMIS in signaling downstream of the T cell antigen receptor (TCR), but the mechanistic underpi

193 Upon recognition of antigen by the T cell antigen receptor (TCR), roquin and regnase-1 protei

194 We demonstrate that upon ligation of the T-cell antigen receptor (TCR), the TCR associates with and

195 n T cells in response to engagement of the T cell antigen receptor (TCR), which induced expression of

196 activation of specific T cells through the T cell antigen receptor (TCR)-CD3 complex.

197 Thus, BATF amplifies T cell antigen receptor (TCR)-dependent expression of tran

198 Studies suggest that a T cell antigen receptor (TCR)-dependent mechanism may be r

199 We found that T cell antigen receptor (TCR)-driven signaling initially d

200 anistically, we demonstrate a link between T cell antigen receptor (TCR)-induced asymmetric expressio

201 operated Ca(2+) channel and contributed to T cell antigen receptor (TCR)-induced Ca(2+) influx, TCR s

202 Analysis of 11 crystal structures of MAIT T cell antigen receptor (TCR)-MR1-AML ternary complexes, a

203 The T cell antigen receptor (TCR)-peptide-major histocompatibi

204 T cell effector functions require the T cell antigen receptor (TCR).

205 cell proliferation and stimulation via the T cell antigen receptor (TCR).

206 igen-presenting molecules by the alphabeta T cell antigen receptor (TCR).

207 ative activation pathway downstream of the T cell antigen receptor (TCR).

208 ing aberrant proliferation mediated by the T cell antigen receptor (TCR).

209 We identified Notch, the T cell antigen receptor and c-Myc as key controllers of T

210 Akt is known to be activated by the T-cell antigen receptor and the cytokine IL-2, but its rol

211 is a critical mediator of signaling by the T cell antigen receptor and the principal costimulatory re

212 eta was significantly lower than with anti-T-cell antigen receptor antibodies (Abs).

213 In this Perspective, we use the T cell antigen receptor as an example with which to review

214 s to tyrosine kinases and may regulate the T-cell antigen receptor biological activities for this cel

215 f immature B cells after engagement of the B cell antigen receptor by suppressing the expression of t

216 th human T-lymphotropic virus type 1; (ii) T cell antigen receptor clonotype repertoires; and (iii) m

217 T cell antigen receptor delta (Tcrd) variable region exons

218 findings indicate that the affinity of the T cell antigen receptor for self antigen drives the differ

219 The T-cell antigen receptor is an assembly of eight single-pas

220 n CD4(+) T cells, prior activation via the T cell antigen receptor limits IL-6's control of STAT1 in

221 These results indicate that the mIgE B-cell antigen receptor plays a critical role in establish

222 erase delta (Poldelta) complex, and T- and B-cell antigen receptor repertoire analysis.

223 han did Foxp3(lo) T(reg)P cells, and had a T cell antigen receptor repertoire and transcriptome disti

224 TEC) is essential for generating a diverse T cell antigen receptor repertoire tolerant to self-antige

225 munocompetent T cells with a self-tolerant T cell antigen receptor repertoire.

226 Analyses of T cell antigen receptor repertoires further support the hy

227 We find that components of T cell antigen receptor signal machinery and several key t

228 The initiation of T cell antigen receptor signaling is a key step that can r

229 mocyte positive selection by enhancing the T cell antigen receptor signaling response to low-affinity

230 ical role in the initiation of B1 but not B2 cell antigen receptor signaling.

231 lear receptors that are rapidly induced by B cell antigen receptor stimulation.

232 tional role for mTORC1 was revealed when a B-cell antigen receptor transgene was found to circumvent

233 AT) is a critical signaling hub connecting T cell antigen receptor triggering to downstream T cell re

234 Herein, we report that ablation of B cell antigen receptor ubiquitination in vivo uncouples t

235 ors display altered alpha3135-145-specific T-cell antigen receptor usage, HLA-DR15-alpha3135-145 tetr

236 chanisms in vitro after activation via the T cell antigen receptor, resulting in antigen-independent

237 ESCRTs) at the plasma membrane to generate T-cell antigen receptor-enriched microvesicles.

238 reg cells separable from signaling via the T cell antigen receptor.

239 in signalling complexes downstream of the T-cell antigen receptor.

240 that are activated after engagement of the T cell antigen receptor.

241 led by signaling pathways initiated by the T cell antigen receptor.

242 s from the cancer microenvironment and the B cell antigen receptor.

243 f the ligands recognized by the gammadelta T cell antigen receptor.

244 ting MR1-Ag complexes are recognized by MAIT cell antigen receptors (alphabeta T cell receptors (TCRs

245 s by selection of somatically hypermutated B cell antigen receptors (BCR) on immune complexes (ICs).

246 l survival relies on signals transduced by B-cell antigen receptors (BCRs).

247 e an extraordinarily diverse repertoire of B-cell antigen receptors (BCRs).

248 responses, T cells harboring high-affinity T cell antigen receptors (TCRs) are preferentially expande

249 In mice, iNKT cells express T cell antigen receptors (TCRs) comprising a unique TCRalp

250 d molecules are subsequently recognized by T cell antigen receptors (TCRs) expressed on the surface o

251 Studies of individual T cell antigen receptors (TCRs) have shed some light on st

252 estion is whether an altered repertoire of T cell antigen receptors (TCRs) is associated with such ex

253 The repertoire of alphabeta T cell antigen receptors (TCRs) on mature T cells is selec

254 features, including variable sequences of T cell antigen receptors (TCRs) that confer antigen specif

255 Interactions of T cell antigen receptors (TCRs) with complexes of self pep

256 The interaction of alphabeta T-cell antigen receptors (TCRs) with peptides bound to MHC

257 spond rapidly to stress despite expressing T cell antigen receptors (TCRs), a hallmark of adaptive im

258 elease for Zap70 kinases at phosphorylated T cell antigen receptors (TCRs).

259 ate response is dependent on IL-33 but not T cell antigen receptors (TCRs).

260 scence, and next-generation sequencing for T-cell antigen receptors (TCRs).

261 s is controlled by tonic signaling through T cell antigen receptors and common gamma chain cytokine r

262 lymphocyte-like cells that lack T cell or B cell antigen receptors and mediate protective and repair

263 g the balance of persistent stimulation of T-cell antigen receptors and specific CD2-induced co-stimu

264 or optimal cell surface expression of mIgE B-cell antigen receptors but not for intracellular IgE exp

265 ndividuals, indicating strong selection of B cell antigen receptors even in the absence of microbiota

266 Activation of T cell antigen receptors induced expression of pro-IL-1bet

267 known to provide a confined space in which B-cell antigen receptors undergo selection.

268 olvent-exposed and therefore accessible to T-cell antigen receptors were predicted to be immunogenic.

269 heckpoint inhibition, mAbs, and engineered T-cell antigen receptors, the incidence and pattern of mal

270 and involving synergistic stimulation via B-cell antigen receptors, toll-like receptor 7 (TLR7), and

271 cells, enriched for self antigen-specific T cell antigen receptors, was also present in healthy host

272 l now was thought to be mediated mainly by B cell antigen receptors.

273 beta-Cell antigen recognition by autoreactive T cells is esse

274 x (MHC) restriction is a unique feature of T cell antigen recognition.

275 of the most noted haptens, are gammadelta T cell antigens, recognized directly by specific gammadelt

276 eralizable strategy for identifying the Treg cell antigens relevant to human autoimmunity.

277 Targeting CD22, an alternative B-cell antigen, represents an alternate strategy.

278 n type 1 diabetes, loss of tolerance to beta-cell antigens results in T-cell-dependent autoimmune des

279 Microfold (M) cells, antigen-sampling cells in the intestine, were pre

280 Stem cell antigen Sca-1 is implicated in murine cancer stem c

281 Stem cell antigen (Sca) -1 is a member of the Ly6 gene family

282 2B adenosine receptors on mouse cardiac stem cell antigen (Sca)-1(+)CD31(-) mesenchymal stem-like cel

283 jects reflects the complex requirements of B-cell antigen signaling, activation, survival, migration,

284 T-cell immunity against stem-cell antigen SOX2 and preserved humoral responses at stu

285 ntigen-specific effector CD8(+) and CD4(+) T cells, antigen-specific cytokine release, inhibition of

286 tion of antigen-specific follicular helper T cells, antigen-specific GC B cells, and high-affinity cl

287 e on development and function of human CD4 T cells, antigen-specific human CD8 T cells, and immunoglo

288 ) lymphocyte-activation gene 3 (LAG3)(+) TR1 cells, antigen-specific proliferative responses, and cyt

289 lity of the VDJdb in the task of exploring T-cell antigen specificities.

290 Herein, we discuss different forms of NK cell antigen specificity and how these responses may be

291 ze AMLs, thereby providing insight into MAIT cell antigen specificity and potency.

292 le in animal models of UL40, a novel HSV-2 T cell antigen that has been correlated with asymptomatic

293 Our data describe a novel aspect of memory T cell antigen threshold sensitivity that may critically r

294 DCs present cancer cell antigens to CD4(+) T cells through Jak-STAT signal

295 e virus (RHDV) for presentation of foreign B-cell antigens to the immune system.

296 cellular immune responses to known CD8(+) T cell antigens was comparable between all strains.

297 ive, as expected, while few novel dominant T cell antigens were IgE reactive.

298 cells (EBV(+) in >90% of cells) expressed B-cell antigens, were often CD30 and PD-L1 positive, and s

299 GD3 can serve as a natural killer T (NKT) cell antigen when presented on CD1d molecules expressed

300 an immunofluorescence assay utilizing whole cell antigens, which are both dangerous and laborious to