ライフサイエンスコーパス: cell envelope

1 mps form tripartite assemblies that span the cell envelope.

2 remodeling the architecture of the bacterial cell envelope.

3 acteria and on the assembly of the bacterial cell envelope.

4 aring as distinct foci or patches around the cell envelope.

5 Most bacteria are surrounded by a complex cell envelope.

6 g to and sequestering histones away from the cell envelope.

7 form multi-protein assemblies that span the cell envelope.

8 Escherichia coli are protected by a complex cell envelope.

9 hat the gene products are distributed in the cell envelope.

10 hat mostly target elements in the parasite's cell envelope.

11 lationships of the various components of the cell envelope.

12 urbing the assembly of the Corynebacterineae cell envelope.

13 teins serve essential roles in the bacterial cell envelope.

14 tiple genes with putative association to the cell envelope.

15 otics because of its durable and impermeable cell envelope.

16 c levels by mediating drug efflux across the cell envelope.

17 f functional properties of the Gram-positive cell envelope.

18 he mechanical integrity of the Gram-negative cell envelope.

19 ria to secrete proteins across their complex cell envelope.

20 glycolipids/lipoglycans of the mycobacterial cell envelope.

21 tiation and incorporation into the cornified cell envelope.

22 elope compared to those with a Gram-negative cell envelope.

23 septal peptidoglycan and constriction of the cell envelope.

24 drugs and other harmful compounds across the cell envelope.

25 lasmic membrane and its transport across the cell envelope.

26 sis of major components of the mycobacterial cell envelope.

27 megadalton nanomachine that spans the entire cell envelope.

28 ntified are known or predicted to affect the cell envelope.

29 as well as the architecture of the bacterial cell envelope.

30 extend a thin cylindrical projection of the cell envelope.

31 cts the speciation of U(VI) on the bacterial cell envelope.

32 I) surface complexes formed on the bacterial cell envelope.

33 panning the inner and outer membranes of the cell envelope.

34 nts, intercellular lipids, and the cornified cell envelope.

35 glycolipids/lipoglycans of the mycobacterial cell envelope.

36 nfection, has a dynamic and immunomodulatory cell envelope.

37 the assembly of the other components of the cell envelope.

38 ome, T-hyperstarvation also destabilizes the cell envelope.

39 in the initial interaction of PAF26 with the cell envelope.

40 urs in the outer layers of the mycobacterial cell envelope.

41 that disrupt the integrity of the bacterial cell envelope.

42 t for both growth and virulence across their cell envelope.

43 exert on molecular targets at the bacterial cell envelope.

44 eir genome and proteins across the bacterial cell envelope.

45 teins across their highly hydrophobic diderm cell envelope.

46 donor, allowing for the full recovery of the cell envelope.

47 in the translocation of these enzymes to the cell envelope.

48 teins form a ~2.4 MDa complex that spans the cell envelope.

49 ly that kills pathogens by perforating their cell envelopes.

50 ays to secrete proteins across their complex cell envelopes.

51 cteria is critical for the assembly of their cell envelopes.

52 ful delivery of large molecules across their cell envelopes.

53 the functionality of gram-negative bacterial cell envelopes.

54 ricrin is a major component of the cornified cell envelope, a highly insoluble structure composed of

55 a model of the dynamics of the mycobacterial cell envelope across space and time.

56 Overall diffusion rates across the cell envelope also occur at similar rates but unexpected

57 es (OMVs) and pili, as well as several other cell envelope alterations.

58 ements for PIC targeting are a Gram-negative cell envelope and a unique cell surface antigen; therefo

59 in complexes can form rigid links across the cell envelope and are therefore subject to physical forc

60 acterial responses related to maintenance of cell envelope and control of secretion pathways.

61 s, which we show is associated with both the cell envelope and cytoplasm.

62 ivo, relating to its capacity to remodel the cell envelope and direct rod formation.

63 The T2SS spans the bacterial cell envelope and extrudes substrates through an outer m

64 , transcribes genes required to maintain the cell envelope and is activated by conditions that destab

65 ry mechanisms that control the nature of the cell envelope and its impact on host innate immune funct

66 ese proteins form a complex that bridges the cell envelope and that has been proposed to cause fusion

67 n of its components, its position within the cell envelope and the interactions between its different

68 rgy metabolism genes; and an upregulation of cell envelope and transport and binding genes in the mut

69 and shear mechanical stress in the bacterial cell envelope and use single-molecule tracking to show t

70 ns and different abilities to diffuse across cell envelopes and interact with lipids and intracellula

71 -encoded proteins, have severely compromised cell envelopes and strong growth defects.

72 the degraded compound, (2) properties of the cell envelope, and (3) the localization of the reacting

73 pidated polysaccharides of the mycobacterial cell envelope, and are targets of anti-tuberculosis drug

74 re essential components of the mycobacterial cell envelope, and their biosynthetic pathway is a well

75 re essential components of the mycobacterial cell envelope, and their biosynthetic pathway is one of

76 recognized to conduct electrons across their cell envelope, and yet molecular details of the mechanis

77 he pAtC58 megaplasmid, ABC transporters, and cell envelope architecture.

78 ways that transport PLs across the bacterial cell envelope are fundamental to OM biogenesis and homeo

79 inery needed for NB translocation across the cell envelope are widespread in Gram-negative bacteria,

80 termediary metabolism, and remodeling of the cell envelope as a means of defending spirochetes agains

81 rence for necromass in the form of microbial cell envelopes as well as plankton and algal detritus.

82 ty acid metabolism, thus critical players in cell envelope assembly.

83 cidification capacity, proteolytic activity, cell envelope associated peptidase (CEP) profile and LC-

84 maturation, and Ag presentation through the cell envelope-associated serine hydrolase, Hip1.

85 baumannii are far-reaching - from impacts on cell envelope biogenesis and maintenance, bacterial phys

86 when the disruption is generated by aberrant cell envelope biogenesis.

87 f lipoproteins in Mycobacterium tuberculosis cell envelope biogenesis.

88 transporters and regulation of mycobacterial cell envelope biogenesis.

89 gest a fundamental role for YciB and DcrB in cell envelope biogenesis.

90 to solute-binding proteins, oxidoreductases, cell envelope biosynthesis enzymes, and others.

91 contrast, BsrG strongly interferes with the cell envelope biosynthesis, causes membrane invagination

92 Many of these genes are implicated in cell-envelope biosynthesis and polysaccharide utilizatio

93 serve that LpqN also interacts with secreted cell envelope biosynthetic enzymes such as Ag85A via pul

94 (PAT) not only play a structural role in the cell envelope but also contribute to the ability of M. t

95 he Gram-positive and Gram-negative bacterial cell envelope, but do not rupture or lyse bacteria.

96 of these toxins target the integrity of the cell envelope, but the full range of growth inhibitory m

97 id tube with associated toxins anchored to a cell envelope by a baseplate and membrane complex.

98 ains enhance the structural integrity of the cell envelope by anchoring the beta-barrels within the p

99 he binding capacity of AMPs to the bacterial cell envelope by calorimetry is difficult because of an

100 at ultimately undermine the integrity of the cell envelope by depleting the inner membrane of phospho

101 F-encoded structures in the native bacterial cell envelope by in situ cryoelectron tomography (CryoET

102 aptic cleft, and would depolarize other hair cells enveloped by the same neuritic process increasing

103 ynthesize an appendage-like extension of the cell envelope called the stalk.

104 or upregulation of genes associated with the cell envelope can modulate vesicle production or remodel

105 tty-acid availability limits growth rate and cell envelope capacity, revealing that fatty-acid synthe

106 model in which fatty acid availability sets cell envelope capacity, which in turn dictates cell size

107 nger for microorganisms with a Gram-positive cell envelope compared to those with a Gram-negative cel

108 Often the outermost cell envelope component, S-layers serve diverse function

109 lated cell wall teichoic acid, a minor Ldb17 cell envelope component.

110 ined, whereas genes underlying production of cell envelope components are especially depleted.

111 Although bacterial cell envelope components function as innate immune molec

112 Both LPS and PG are essential cell envelope components that are synthesized independen

113 ction, host immune cells recognize bacterial cell envelope components through cognate receptors.

114 ibition potentially prevents damage of large cell envelope components, but not host digestion.

115 Loss of BamE altered cell envelope composition, leading to slower growth and

116 tensive and tightly integrated modulation of cell envelope constituents, chemotaxis/motility machiner

117 A unique, protective cell envelope contributes to the broad drug resistance o

118 entration of U(VI) adsorbed on the bacterial cell envelope control the kinetics of U(VI) bioreduction

119 localization of Rod complexes based on local cell-envelope curvature.

120 which causes septal defects and catastrophic cell envelope damage.

121 el gut microbiota, and to sensitively detect cell-envelope damage caused by antibiotics or previously

122 sor sodium dodecyl sulfate (SDS), indicating cell envelope defects, as well as to EDTA.

123 The bacterial flagellar motor, a cell-envelope-embedded macromolecular machine that funct

124 Moreover, isolated bacterial cell envelopes, encompassing inner and outer membranes,

125 centration causes a pressure drop across the cell envelope, followed by an active recovery.

126 f Mycobacterium smegmatis is exported to the cell envelope following cleavage of its signal peptide a

127 lipidic elements are transported across the cell envelope for cell-wall biosynthesis is unclear.

128 doglycan and membrane syntheses critical for cell envelope formation during polar growth.

129 K-rich clay occurs within and exterior to cell envelopes, forming where the supply of Fe had been

130 Chp2 is localized to the cell envelope fraction, consistent with its role in DAT

131 Revealing the molecular architecture of the cell envelope frames our understanding of its mechanical

132 nes identified encode proteins implicated in cell envelope function.

133 mongst bacteria and commonly associated with cell envelope function.

134 Within the cell envelope, Galf residues are linked together to affo

135 e the same synthetic interactions with other cell envelope genes.

136 okaryotes, mycobacteria decorate their major cell envelope glycans with minor covalent substituents w

137 Much of what we know about the mycobacterial cell envelope has been gleaned from model actinobacteria

138 complex network connecting in vivo fitness, cell envelope homeostasis and resistance to antibiotics.

139 sence of Mla; providing another link between cell envelope homeostasis and stringent response.

140 (a member of the LiaFSR system that controls cell envelope homeostasis), from daptomycin-resistant En

141 cteria for specific functions in maintaining cell envelope homeostasis.

142 in capsule biosynthesis and maintaining the cell envelope homeostasis.

143 role of the physical state of the bacterial cell envelope (i.e., particulate versus soluble) in host

144 eins from the bacterial cytoplasm across the cell envelope in a single step.

145 e and mechanical properties of the S. aureus cell envelope in both types of clinically relevant strai

146 between the inner and outer membranes of the cell envelope in Gram-negative bacteria, maintains cell

147 f phosphates and carboxylate groups from the cell envelope in the bioassociation of Eu(III).

148 complex called the divisome, which spans the cell envelope in the plane of division.

149 also incorporated into the loricrin knockout cell envelope, in addition to the small proline rich pro

150 le, the outermost layer of the mycobacterial cell envelope, in modulation of the host immune response

151 amnose polysaccharides that are critical for cell envelope integrity and cell shape and also represen

152 rucella virulence that functions to maintain cell envelope integrity and influences cell division.

153 ve PBP1B function in vivo and maintenance of cell envelope integrity during division.

154 an essential synergistic role in maintaining cell envelope integrity of Escherichia coli.

155 antagonistically to IreK and interfere with cell envelope integrity, antimicrobial resistance, and G

156 ies have indicated the importance of ECA for cell envelope integrity, flagellum expression, and resis

157 ensitivity to treatments that compromise the cell envelope integrity.

158 ytoskeleton, and its role beyond maintaining cell envelope integrity.

159 acConkey plates, indicating an alteration in cell envelope integrity.

160 l in human serum, antibiotic resistance, and cell envelope integrity.

161 Cell shape and cell-envelope integrity of bacteria are determined by th

162 ow the molecular components of the bacterial cell envelope interact with each other to mediate cell w

163 Its cell envelope is a common antibiotic target and has a un

164 The Mycobacterium tuberculosis cell envelope is a critical interface between the host a

165 The bacterial cell envelope is a crucial first line of defense for a s

166 Therefore, the planctomycetal cell envelope is considered exceptional and their cell p

167 bacteria, phospholipid transport across the cell envelope is critical to maintain the outer membrane

168 The mycobacterial cell envelope is crucial to host-pathogen interactions a

169 The mycobacterial cell envelope is extremely hydrophobic, which contribute

170 The outermost surface of this cell envelope is formed by capsular polysaccharides that

171 This cell envelope is the basis of many of the pathogenic fea

172 stinctive component of the Corynebacterineae cell envelope is the mycolyl-arabinogalactan (mAG) compl

173 The defining feature of the Gram-negative cell envelope is the presence of two cellular membranes,

174 hich these lipids are transported across the cell envelope is(are) much less known.

175 into Esx-1 export, nonsense suppression, and cell envelope lipid biogenesis.

176 Cell envelope lipid biosynthesis is the target of a numb

177 rane protein large (MmpL) proteins transport cell envelope lipids and siderophores that are important

178 Cell envelope lipids are also mycobacterial virulence fa

179 In addition, cell envelope lipids are mycobacterial virulence factors

180 sporters that export mycolic acid-containing cell envelope lipids.

181 CR signaling is inhibited by M. tuberculosis cell envelope lipoglycans, such as lipoarabinomannan and

182 The LytR-CpsA-Psr proteins are important for cell envelope maintenance in many Gram-positive species.

183 ys a role in genetic information processing, cell envelope maintenance or energy production.

184 llular functions including sterol uptake and cell envelope maintenance.

185 rotein complex, mechanical forces within the cell envelope make the bacteria more susceptible to meta

186 We show that the cell envelope material properties do not change after hy

187 PG), a major component of the B. burgdorferi cell envelope, may contribute to the development and per

188 dulating the function of proteins within the cell envelope, mechanical stress has the potential to re

189 st that CA-MRSA success might be driven by a cell-envelope mediated selective advantage across divers

190 In addition to a distinctive cell envelope mediating critical interactions with the h

191 ns observed in the DeltaMceG mutant, such as cell envelope modifications, suggest a pleiotropic funct

192 esis, surface protein display, and D-alanine cell envelope modifications.

193 The fragmentation of these representative cell envelope molecules provides insight into the biocid

194 It was found that FNA broke down a range of cell envelope molecules.

195 partially achieved with exposure to symbiont cell-envelope molecules.

196 effects, but their impact on bacterial outer cell envelope needs to be studied in detail.

197 (two membranes) and monoderm (one membrane) cell envelopes occurred in Bacteria.

198 e present the first detailed analysis of the cell envelope of an important but neglected member of th

199 The cell envelope of Gram-negative bacteria is a multilayere

200 The double-membrane cell envelope of Gram-negative bacteria is a sophisticat

201 The cell envelope of Gram-negative bacteria is synthesized a

202 Moreover, the cell envelope of Gram-negative bacteria such as E. coli

203 The cell envelope of gram-negative bacteria, a structure com

204 complex, a widely conserved component of the cell envelope of Gram-negative bacteria, is required to

205 nderstood how the MAC perturbs the composite cell envelope of Gram-negative bacteria.

206 y in the outer membrane has long defined the cell envelope of Gram-negative bacteria.

207 The cell envelope of Gram-positive bacteria generally compri

208 ully coordinate constriction of a tripartite cell envelope of inner membrane, peptidoglycan (PG), and

209 predominant stress-bearing structure in the cell envelope of most bacteria, and also a potent stimul

210 The cell envelope of Mycobacterium tuberculosis is notable f

211 d a last-resort antibiotic, by targeting the cell envelope of pathogenic bacteria.

212 ng two different forms of the staphylococcal cell envelope of Staphylococcus aureus RN4220 and USA300

213 been described, each designed to breach the cell envelope of target bacteria.

214 tered the hydrophobicity and rigidity of the cell envelope of the bacilli without significantly alter

215 cell wall is integrated into the protective cell envelope of the bacterium may identify new antibact

216 haride-specific chitoporin, VcChiP, from the cell envelope of the V. cholerae type strain O1.

217 ein (MOSP) is a prominent constituent of the cell envelope of Treponema denticola (TDE) and one of it

218 gy of mycobacteria is dominated by a complex cell envelope of unique composition and structure and of

219 lts suggest a novel function for OmpA in the cell envelope: OmpA competes with the inner membrane pro

220 r stability on many proteins exported to the cell envelope or beyond, including bacterial virulence f

221 by removing barriers to the external world (cell envelopes) or by destroying their genetic identity

222 nt properties on the bacterium in respect of cell envelope organisation and interaction with the envi

223 Cell envelope outer membrane lipids change systematicall

224 , the particulate form of the staphylococcal cell envelope (PCE) induced the production of chemokine

225 NA packaging and implicated in Gram-negative cell envelope penetration.

226 mecA protects the bacteria against increased cell-envelope permeability under subinhibitory cefoxitin

227 singly appreciated for its role in bacterial cell envelope physiology.

228 Molecular components of the Brucella abortus cell envelope play a major role in its ability to infect

229 antibiotics, virulence factors, peptides and cell envelope precursors.

230 hear (but not hydrostatic) stress within the cell envelope promotes disassembly of the tripartite eff

231 Cell envelope properties and the tetrachloroethene reduc

232 Cell envelope properties of the Desulfitobacterium strai

233 ty of SLO, DNase, and Streptococcus pyogenes cell envelope protease in vitro.

234 e Psp system in persister cell formation and cell envelope protection in bacterial pathogens and prov

235 Bacterial cell envelope protein (CEP) complexes mediate a range of

236 echanical forces can inhibit the function of cell envelope protein assemblies in bacteria and suggest

237 mic analysis, to date, of the changes in the cell envelope protein profile of F. succinogenes S85 in

238 the streptococcal CXC protease, S. pyogenes cell envelope proteinase, we developed a combination vac

239 mitigation of stress generated by misfolded cell envelope proteins but promotes expression of genes

240 lfide exchange-mediated folding of bacterial cell envelope proteins during periods of oxidative stres

241 We go on to identify cell envelope proteins that are necessary for the import

242 enzymatic subunits, bind cohesin modules of cell envelope proteins, thereby anchoring the cellulosom

243 coli to alleviate stress caused by misfolded cell envelope proteins.

244 n interesting research material for defining cell-envelope proteins without experimental cell disrupt

245 tic, for the capture of the Escherichia coli cell envelope proteome and its high-resolution fractiona

246 Our results indicate that the cell envelope proteome undergoes extensive rearrangement

247 e assembled F-pilin subunits relative to the cell envelope, providing insights into the F-like type I

248 ng blocks, i.e. PLs, are shuttled across the cell envelope remain elusive.

249 ation and dynamics of glycolipids within the cell envelope remain poorly understood.

250 etry, and SYTOX green assays showed that the cell envelope remained intact to a high degree at the mi

251 rast, compared with PCE, the soluble form of cell envelope (SCE), which was derived from PCE by treat

252 ing reveals a novel role for FtsK in linking cell envelope septation events and yields further eviden

253 If antibiotics cross bacterial cell envelopes slowly to reach their target, there is a

254 sion, adhesion and retraction powered by the cell-envelope spanning type IVa pilus machine (T4aPM).

255 functionality.IMPORTANCECaudovirales encode cell envelope-spanning proteins called spanins, which ar

256 consists of the F pilus attached to a thin, cell envelope-spanning stalk, whereas the F4 structure c

257 her between the OM and PG and is crucial for cell envelope stability(4); however, most other Gram-neg

258 cross-linked proteins, which together confer cell envelope stability.

259 findings to propose a model of Gram-negative cell envelope stabilization that includes cell cycle con

260 is important for survival under a number of cell envelope stress conditions and in gastrointestinal

261 t in addition to anaerobiosis, adaptation to cell envelope stress is a critical requirement for E. co

262 LiaR is a 'master regulator' of the cell envelope stress response in enterococci and many ot

263 factor, sigma(E) , is a key regulator of the cell envelope stress response in Streptomyces coelicolor

264 ological insight into the sigma(E) -mediated cell envelope stress response in the genus Streptomyces.

265 l, these data demonstrate that RpoE is a key cell envelope stress response regulator and, similar to

266 k protein (Psp) system is a highly conserved cell envelope stress response required for virulence in

267 Although several cell envelope stress response systems have been well des

268 an extracellular sentinel that activates the cell envelope stress response.

269 ss, indicating OmpU is not essential for the cell envelope stress responses or RpoE function.

270 ECF factors typically respond to cell wall/cell envelope stress, iron levels, and the oxidation sta

271 The analogue also upregulated cell envelope stress-inducible promoters piniBAC and pcl

272 at Amj is expressed under the control of the cell envelope stress-response transcription factor sigma

273 ignal transduction system that is induced by cell envelope stress.

274 ry decisions, most notably the adaptation to cell envelope stress.

275 The cell envelope structurally and functionally varies acros

276 s enhance our understanding of mycobacterial cell envelope structure and dynamics and have implicatio

277 Together, sigma(M) and sigma(X) regulate cell envelope structure to decrease access of nisin to i

278 With functions that range from cell envelope structure to signal transduction and trans

279 the system indicate adaptation to different cell envelope structures, bacterial lifestyles, and/or b

280 e pharmaceutical antibiotics that act on the cell envelope such as vancomycin and daptomycin.

281 After blocking the bacterial cell envelope sulfhydryl sites using a qBBr treatment, t

282 nd L-glutamate, thereby coupling protein and cell envelope synthesis with the metabolic status of the

283 Gram-negative bacteria have a cell envelope that comprises an outer membrane (OM), a p

284 otected by an unusual and highly impermeable cell envelope that is critically important for the succe

285 lagella are complex machines embedded in the cell envelope that rotate a long extracellular helical f

286 aerobiales are remnants of an ancient diderm cell envelope that was present in the ancestor of the Fi

287 r adaptive success is linked to their unique cell envelopes that are extremely resistant to chemical

288 urface-associated carbohydrates of the Ldb17 cell envelope: the Gro3P decoration of the major surface

289 encoding proteins that are localized to the cell envelope; these include metallopeptidases, multidru

290 A will break bonds in molecules found in the cell envelope, thus causing cell lysis.

291 obust barrier of hydrophobic double membrane cell envelope, thus, leading to drug-resistance in Gram-

292 n of cytoplasmic volume to the growth of the cell envelope to preserve cellular integrity.

293 nslocated across the different layers of the cell envelope to their final extra-cytoplasmic location.

294 ir localization within the loricrin knockout cell envelope via immunoelectron microscopy.

295 recognized the peptide-target complex in the cell envelope, we next analyzed substrate binding by the

296 cnes, and complete breaches in the bacterial cell envelope were observed.

297 lecules representing components found in the cell envelope were treated with FNA at 6.09 mg N/L (NO(2

298 247 may exert some of its effects within the cell envelope whereas other activities occur in the cyto

299 Gram-negative bacteria and their complex cell envelope, which comprises an outer membrane and an

300 The transition between cell envelopes with one membrane (Gram-positive or monod