1 We conclude that in RN46A neuronal
cells, hypoxia activates an autocrine-paracrine antiapop
2 e domain 2 (PHD2) plays an important role in
cell hypoxia adaptation by regulating the stability of H
3 beta-
cell hypoxia and apoptosis were evaluated by immunohisto
4 ing of the blood vasculature, causing cancer
cell hypoxia and death in distant avascular regions.
5 vessel density together with increased tumor
cell hypoxia and death.
6 In NDRG3-deficient
cells, hypoxia-
and lactate-induced inhibition of ER-to-
7 sulted in a dose-dependent reduction of beta-
cell hypoxia,
but beta-cell apoptosis was only reduced b
8 In CB
cells, hypoxia caused inhibition of TASK-like channels,
9 In primary human endothelial
cells, hypoxia,
desferrioxamine, or infection with Ad2/H
10 In pVHL-deficient
cells, hypoxia did not decrease the Na-K-ATPase activity
11 s (DiOC7 staining), and an increase in tumor
cell hypoxia (
EF5 staining).
12 In the remaining
cells, hypoxia either did not elicit any change or produ
13 Here, we show that in HCC
cells, hypoxia elevates expression of Cav1, which then a
14 re that in the human breast carcinoma BT-549
cells hypoxia enhanced expression of the transcription f
15 hat induces secretion of HMGB1 by epithelial
cells, hypoxia establishes a microenvironment that favor
16 In MIA PaCa-2 pancreatic cancer
cells, hypoxia increased p65-NFkappaB DNA binding and NF
17 In this paper, we show that, in cancer
cells, hypoxia increased the levels and activity of the
18 In Muller
cells, hypoxia increased the phosphorylation of cPLA(2)
19 In current-clamped CA1 pyramidal
cells hypoxia induced a rapid, near-complete depolarizat
20 In Hep3B or HepG2
cells hypoxia induces neither expression of PCBP nor for
21 an primary retinal microvascular endothelial
cells, hypoxia induces the expression of ADORA2A by acti
22 , we show that metabolic stress induces beta-
cell hypoxia inducible factor 2alpha (HIF-2alpha), which
23 Loss of smooth muscle
cell hypoxia inducible factor-1alpha underlies increased
24 ficiently to stabilize intestinal epithelial
cell hypoxia-
inducible factor (HIF).
25 Also, in normal fibroblasts and retinal
cells, hypoxia inhibited the mTOR pathway and suppressed
26 In mouse lung and mammary tumor
cells, hypoxia led to increases in cell adhesion, clotti
27 In intervertebral disc
cells, hypoxia promotes expression of Notch signaling pr
28 ted this mechanism in a cultured endothelial
cell hypoxia-
reoxygenation model, in a rat model of hemo
29 yocardial I/R injury and H9c2 cardiomyoblast
cells hypoxia/
reoxygenation (H/R) was used to assess whe
30 In cultured human umbilical vein endothelial
cells, hypoxia/
reoxygenation stimulated apoptosis.
31 In human
cells, hypoxia restores steady-state levels of Fe-S clus
32 Here, we show that in nucleus pulposus
cells, hypoxia robustly induces PHD3 expression and, to
33 In most normal
cells, hypoxia stabilizes hypoxia-inducible transcriptio
34 In colon cancer
cells, hypoxia stimulated multiple K-ras effector pathwa
35 of treatment were needed before severe tumor
cell hypoxia was detected in K1735 tumors.
36 m therapeutic angiogenesis inhibition, tumor
cell hypoxia was evaluated as a marker of ischemia using
37 In primary glioma-derived CD133 negative
cells, hypoxia was able to induce neurospheres and hESC
38 ng the molecular mechanisms induced by tumor
cell hypoxia with a special emphasis on therapeutic resi