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1 cus production, tissue remodeling and immune cell infiltration.
2 tokeratin 19-positive metaplasias and immune cell infiltration.
3 e presence of cGAS, as was skin inflammatory cell infiltration.
4 of Tnfr1(-/-)/Mdr2(-/-) mice indicated TH17 cell infiltration.
5 sinophilic, neutrophilic, and ST2(+)CD4(+) T-cell infiltration.
6 priming step to improve intratumoral immune cell infiltration.
7 microenvironment by inducing intratumoral T cell infiltration.
8 toxicity associated with induction of immune cell infiltration.
9 damage response genes, and decreased immune cell infiltration.
10 ot, with increased IFNgamma content and CD8+ cell infiltration.
11 umor M1 macrophage polarization and CD8(+) T-cell infiltration.
12 scular permeability, edema, and inflammatory cell infiltration.
13 lin, MHC class I, antigen presentation and T-cell infiltration.
14 NA repair status accurately predicted immune cell infiltration.
15 s followed with much delay by reduction in T cell infiltration.
16 ed corneal edema, and decreased inflammatory cell infiltration.
17 nophilia, goblet cell hyperplasia, and T(H)2 cell infiltration.
18 alter viral load, corneal edema, and immune cell infiltration.
19 es in macrophage polarization and enhanced T cell infiltration.
20 indicating ubiquitous variability in immune cell infiltration.
21 interstitial fibrosis, and prevented immune cell infiltration.
22 sitive area, but a marked decrease in CD3(+) cell infiltration.
23 to postmortem measurements of colonic immune cell infiltration.
24 in protein repression along with decreased T-cell infiltration.
25 ion profiles associated with CD4, CD8, and B cell infiltration.
26 ppressor cells and inhibition of cytotoxic T-cell infiltration.
27 othelial cell activation, and intratumoral T-cell infiltration.
28 diffuse alveolar damage with perivascular T-cell infiltration.
29 re associated with robust (10-fold) CD8(+) T cell infiltration.
30 uction in C3b/c and C9 deposition and innate cell infiltration.
31 sence of tumor cells was required for immune cell infiltration.
32 orresponding with patterns of greater immune cell infiltration.
33 ed fibrosis, increased vascularity, and mast cell infiltration.
34 cking of these chemokines inhibited CD8(+) T-cell infiltration.
35 exhibited autoimmune phenotypes, including T cell infiltration.
36 d mice correlated with intratumoral CD8(+) T-cell infiltration.
37 ation with patient survival and tumor immune cell infiltration.
38 ion of tumor-residing cDC1s overcomes poor T-cell infiltration.
39 n the mouse cancer model boosted cytotoxic T cell infiltration.
40 itic cells, inducing immune and inflammatory cell infiltration.
41 anced disease mediated by pulmonary CD8(+) T cell infiltration.
42 val benefit and positively correlated with T cell infiltration.
43 inflammatory cytokine expression and myeloid cell infiltration.
44 as a potential physical barrier to hinder T cell infiltration.
45 ciency in mice leads to reduced lung myeloid cell infiltration, abnormal alternatively activated macr
48 gy scores and alleviated airway inflammatory cell infiltration after adoptive transfer into mice; the
49 N via (1) enhancing renal pathogenic myeloid cell infiltration and (2) direct effects on M/M polariza
50 areas of the pancreas with respect to immune cell infiltration and a changed ratio between the number
51 ilieu with a reduction of pathogenic myeloid cell infiltration and a marked accumulation of eosinophi
53 ells recruited in vivo) induces local immune-cell infiltration and activated dendritic cells, evoking
54 se correlation between Arf1 expression and T-cell infiltration and activation along with patient surv
56 ptional analysis were used to measure immune cell infiltration and activation in the skin of Rubcn(+/
59 reased immune complexity, increased CD8(+) T-cell infiltration and activity, and decreased Treg frequ
60 enhanced disease severity due to increased T cell infiltration and altered polarization and pathogeni
61 f the PD-1/PD-L1 T cell checkpoint induces T cell infiltration and anticancer responses in murine and
63 sion of chemokine transcripts, higher immune cell infiltration and augmented TCR clonal diversity amo
66 mma(High)/RXRalpha(S427F/Y) impairs CD8(+) T-cell infiltration and confers partial resistance to immu
70 and anti PD-1 cooperatively induces CD8(+) T-cell infiltration and decreases levels of proteins that
71 is exacerbates the inflammatory responses, T cell infiltration and demyelination following focal spin
74 38A) rapidly induced skin acanthosis, immune cell infiltration and expression of psoriasis-associated
76 ons of Plin2 are primary mediators of immune cell infiltration and fibrotic injury in livers of obese
77 e and IDO1 inhibitor enhanced intratumoral T cell infiltration and function, but adding anti-PD-L1 an
80 ated the association of stemness with immune cell infiltration and genomic, transcriptomic, and clini
83 ified an association between decreased CD8 T cell infiltration and increased glycolysis in microsatel
85 nalysis revealed that EP favors inflammatory cell infiltration and junctional epithelium, cementum wi
86 ed by airway and adjacent parenchymal immune cell infiltration and mucus production for at least 7 wk
87 ollowing NACT, increased natural killer (NK) cell infiltration and oligoclonal expansion of T cells w
88 suggest conduit biocompatibility and Schwann cell infiltration and organization within the conduit an
89 ge, LivKO mice showed increased inflammatory cell infiltration and proinflammatory gene expression in
90 rapeutic combination partners that augment T-cell infiltration and proliferation in so-called immune
93 may have poor prognosis despite high CD8+ T cell infiltration and provide CD274 as a simple biomarke
96 Enforced expression of CIITA increased T cell infiltration and sensitized tumors to anti-PD-1 the
97 sease burden (percentage of bone marrow mast cell infiltration and serum tryptase levels) with molecu
98 dministration also enhanced tumor-specific T-cell infiltration and spatially redistributed CD8(+) T c
101 panied by significant weight loss and immune cell infiltration and the expression of early inflammato
102 ealed evidence of treatment response, immune cell infiltration and the migratory path of infiltrating
103 inhibits pathways that lead to inflammatory cell infiltration and the production of inflammatory cyt
104 with talimogene laherparepvec on cytotoxic T cell infiltration and therapeutic efficacy of the anti-P
105 T cells displayed reduced cerebral CD4(+) T-cell infiltration and thrombotic activity following expe
106 intervention markedly decreases swelling, T-cell infiltration and tissue fibrosis while significantl
107 umor transcriptomes was used to infer immune cell infiltration and to categorize tumors into immune s
108 mor immune microenvironment including immune cell infiltration and upregulation of PD-L1 expression p
110 on of in vitro cell activities, and enhanced cell infiltration and vascularization upon in vivo impla
111 d active granuloma formation with abundant T cell infiltration and were associated with significantly
112 bited less neutrophils or polymorpho nuclear cells infiltration and had improved efferocytosis compar
113 nflammation as evidenced by increased immune cells infiltration and release of cytokines and chemokin
114 lasia, inflammatory cytokine release, immune cell infiltration, and a subsequent reduction in skin sw
115 zed by increased collagen deposition, immune cell infiltration, and alpha-smooth muscle actin (alpha-
116 ressing livers display necrotic foci, immune cell infiltration, and altered hepatocyte morphology.
117 erythema and induration, CD4(+) and CD8(+) T-cell infiltration, and attenuated global gene activation
119 ssessed by changes in ear thickness, myeloid cell infiltration, and cytokine and chemokine secretion.
121 rentiation, increased myofibroblasts, immune cell infiltration, and increased matrix deposition.
123 eovascularization, re-epithelization, immune cell infiltration, and mRNA levels of angiogenic and pro
124 activation of the complement system, immune cell infiltration, and phagocytosis; pathways that may d
125 on of pulmonary vascular cells, inflammatory cell infiltration, and regresses established pulmonary h
126 on measured via CT, alveolar wall thickness, cell infiltration, and surfactant protein A concentratio
128 is, degrades versican, promotes inflammatory cell infiltration, and thus contributes to sporadic AAD
130 lysis predicts hematopoietic cell number and cell infiltration are modulated by CR1(long), but not CR
132 im to assess the usefulness of measures of T-cell infiltration as prognostic biomarkers in 640 stage
134 veolar bone volume and enhanced inflammatory cell infiltration, as well as an increased number of ost
135 tratumoral MYXV delivery and observed immune cell infiltration associated with tumor necrosis and gro
136 yed increased tissue damage and inflammatory cell infiltration at early time points during injury but
139 xpression of apelin facilitated graft immune cell infiltration, blunted vascular repair, and worsened
141 gnificantly suppressed total leukocyte and T-cell infiltration by 50%-68%; epidermal thickness by 60%
143 e secreted CXCL10, in turn, stimulated the T-cell infiltration by serving as the ligand and chemoattr
145 sful wound healing, aberrant immune-mediated cell infiltration can lead to pathological inflammation
146 , alpha-smooth muscle actin, and mononuclear cell infiltration (CD11b(+) Ly-6c(hi) monocytes and CD11
147 MIP-2, RANTES, and TNF-alpha), inflammatory cell infiltration (CD3 + T cells, macrophages, and neutr
148 uates ISO-mediated increases in inflammatory cell infiltration, collagen deposition and fibrosis.
149 urrence rate and shows more anterior chamber cell infiltration compared with HLA-B27-negative patient
150 These results suggest that increased myeloid cell infiltration contributes to autoreactive CD4 T cell
152 between checkpoint based fitness and tumor T-cell infiltration, cytolytic activity, and abundance (tu
153 expression, chemokine expression, and immune cell infiltration density change during progression to S
155 r, melanocyte proliferation, or inflammatory cell infiltration, did not explain melanoma susceptibili
156 sition through LOXL2 suppression increases T cell infiltration, diminishes exhausted T cells, and abr
157 ed groups showed virtually no sign of immune cell infiltration, except minimal infiltration in white
158 with DNA repair gene variants but without T cell infiltration exhibited upregulation of TGF-beta and
159 41BB agonistic Abs led to increases in CD8 T cell infiltration followed by tumor regression in murine
160 were analyzed for vascularity, inflammatory cell infiltration, growth pattern, and tumor expression
161 uppressive function, (ii) increased CD8(+) T-cell infiltration, (iii) enhanced M1/M2 macrophage ratio
162 Based on the positive prognostic value of T cell infiltration, Immunoscore has been developed and va
164 y somatic mutations and the extent of immune cell infiltration in adenomatous premalignancy and assoc
166 ysical disability and cleared the brain of T-cell infiltration in an EAE mouse model of multiple scle
167 growth regulatory kinase Erk5 can increase T-cell infiltration in an established Pten-deficient mouse
168 gene expression profile and decreased immune cell infiltration in an intradermal model of infection y
173 tment with FOLR1-TCB induced strong CD8(+) T-cell infiltration in HeLa tumors, where (89)Zr-Df-IAB22M
174 ral pathways, IFN signaling, and cytotoxic T cell infiltration in human cancers, while a FBXO44-immun
176 by myeloid cells is key for orchestrating T cell infiltration in immunoreactive and immunoresponsive
177 between disease outcomes and high levels of cell infiltration in lungs including CD11b(+)CD16(hi) ma
180 ha/NFkappaB signaling, which promotes immune cell infiltration in regressing and residual tumors.
184 ion resulted in a reduction of myeloid and T cell infiltration in the central nervous system and a si
185 rrier (BBB) disruption and peripheral immune cell infiltration in the cerebellum following blast expo
186 ssociated with decreased inflammatory immune cell infiltration in the CNS and increased Treg cells in
187 in stem, and on axon degeneration and immune cell infiltration in the distal portion of the facial ne
190 tractant protein 1]), increases inflammatory cell infiltration in the kidney, reduces telomerase expr
191 sed MRL.Fas(lpr) mouse survival, decreased T cell infiltration in the kidneys, and reduced T cell cyt
194 gG4 level, abundance of IgG4 enhanced plasma cell infiltration in the portal region of the liver, and
195 nterface hepatitis with IgG4 positive plasma cell infiltration in the portal region, without evidence
196 is an autoimmune disease characterized by T-cell infiltration in the skin that leads to fibrosis, wh
198 mmatory phenotype, and impairs FOXP3(+)/Treg cell infiltration in the spinal cord of hSOD1(G93A) mice
199 t the SA-IL-4 fusion protein prevents immune-cell infiltration in the spinal cord, decreases integrin
201 ssues showed significantly more inflammatory cell infiltration in the WT ligated but not in the TLR9(
205 ere higher proportions of anti-cancer immune cells infiltration, including activated memory CD4+ T ce
206 h lower levels of Th1 cytokines, decreased T cell infiltration, increased B cell numbers, and decreas
207 h were characterized by increased effector T-cell infiltration, increased effector T-cell function, a
208 rged retroperitoneal lymph nodes, and immune cells infiltration, indicating that blocking VEGF-C sign
209 ckout (I-SGPL(-/-)) augmented massive immune cell infiltration initiating colitis with lesions and ca
210 neous hyperplasia in this model, decreased T cell infiltration, interleukin (IL)-22 transcription, an
214 tumor-associated macrophage (TAM) and CD8 T cell infiltration into subcutaneously implanted murine l
218 ed skin is required to direct effector CD8 T cell infiltration into the challenge site to elicit CHS,
219 In mice, TFH cells accordingly promote B cell infiltration into the CNS and the severity of MS an
224 autoimmune process initiates first with a T cell infiltration into the islets, where they have restr
227 ardiomyopathy, characterized by inflammatory cell infiltration into the myocardium and a high risk of
230 ce with chronic EAE, SA-IL-4 inhibits immune-cell infiltration into the spinal cord and completely ab
231 that NSD1 inactivation results in reduced T cell infiltration into the tumor microenvironment, impli
232 e inflamed tumor environment with enhanced T-cell infiltration into tumors and T-cell-mediated cytoto
233 elevated pulmonary congestion, inflammatory cell infiltration, iron overload, and secretion of IL-6
234 tract integrity is degraded in areas where T-cell infiltration is highest, providing a noninvasive me
236 distribution of desmoplastic elements and T-cell infiltration is necessary to delineate their roles.
238 that Gal1 blockade increases intratumoral T cell infiltration, leading to a better response to anti-
240 and host cells, and baseline intratumoral T cell infiltration may improve response likelihood to ant
241 rs, since the potential adverse effect on NK cell infiltration might limit the antitumor activity of
243 reduced weight loss, pulmonary inflammatory cell infiltration, mucus production, and airway resistan
245 ce burn) and determined the degree of immune cell infiltration, NETosis, and the cytokine levels in t
246 c analysis was used to evaluate inflammatory cell infiltration, numbers of osteoblasts and osteoclast
247 that deletion of TSP-1 reduced inflammatory cell infiltration of muscle fibers, but only early in di
249 vealed significant loss of BMAT with myeloma cell infiltration of the marrow, whereas BMAT was restor
250 However, although there is considerable T cell infiltration of the maternal decidua, the functiona
251 p120-catenin further prevents diffuse glioma cell infiltration of the mouse brain with marginalized m
252 FGR and pre-eclampsia are associated with T-cell infiltration of the placenta and placental patholog
256 re causal, either by interfering with immune cell infiltration or by enhancing melanoma cell growth.
257 ci-cellular infiltration with rare epidermal cell infiltration or necrosis, were accounted for in a p
258 ucicellular infiltration with rare epidermal cell infiltration or necrosis, were accounted for in a p
259 phenotype and promoted intratumoral CD8(+) T-cell infiltration, overcoming the exclusion effect; TGFb
261 NA expression (P = 0.03), and 114% greater T-cell infiltration (P = 0.005) compared to sham-operated
264 mor cytokine/chemokine signature, improved T-cell infiltration, reduced markers of T-cell exhaustion,
266 ting chemokines, resulting in improved CAR-T cell infiltration, remodeling of the tumor microenvironm
268 ue and inversely correlated with cytotoxic T cell infiltration, suggesting that HE4 may cause deregul
269 SCLC human patients showed negligible immune cell infiltration, supporting testing MYXV as an ablativ
270 ysis revealed significantly decreased immune cell infiltration, synthesis of reactive oxygen species,
271 ity of neurons, due to cell death and immune cell infiltration that may account for the observed unde
272 ithelium (RPE) injury associated with immune cell infiltration, the nature of immune cell responses t
273 ene expression pattern that indicated immune cell infiltration; this tumor type was associated with t
274 he T-reg cell population and reducing immune cell infiltration, thus promoting longer-term infection.
275 AHR in asthma are related to a shift in mast cell infiltration to the airway epithelium, and that mas
277 eatment promoted transient polymorphonuclear cell infiltration to the vaginal cavity and protected ag
278 tumor growth in mice, increased tumor immune cell infiltration, upregulated PD-L1 on tumors, and sens
280 Intratumoral basophils enhanced CD8(+) T-cell infiltration via production of chemokines CCL3 and
282 (5.5 +/- 0.1 vs 7.8 +/- 0.2 um; p < 0.0001), cell infiltration was lower (20 +/- 2 vs 32 +/- 2 n/fiel
284 on and pre-eclampsia, whereas CD79alpha(+) B-cell infiltration was only apparent with reduced fetal g
285 , which identifies tumors with a high immune cell infiltration, was shown to enrich for response to a
286 evels, blood-brain barrier leakage, and/or T cell infiltration, well before neurodegeneration occurs.
288 f epidermal hyperplasia and T-cell/dendritic cell infiltration were increased in AD tissues of all pa
289 ond infection, cytokine responses and innate cell infiltration were largely comparable to primary inf
290 neoantigen load) and the degree of CD8(+) T cell infiltration were not associated with clinical resp
292 at VUE is driven predominantly by maternal T cell infiltration, which is significantly different from
293 eratinocytes associated with a marked CD4+ T cell infiltration, which peaked on days 10-11 after trea
294 EP4 cKO colon stroma showed enhanced immune cell infiltration, which was accompanied by increased pr
295 ited dermal disorganization and inflammatory cell infiltration, which were improved in the 3 treated
296 ver, the reason some tumours have high CD8 T cell infiltration while others do not remains unclear.
297 associated with macrophage, CD4, CD8, and B cell infiltration with increased formation of tertiary l
300 ivation impairs tumor progression and immune cell infiltration without affecting cell cycle arrest in