ライフサイエンスコーパス: cell nucleus

1 cilitate compaction and rearrangement in the cell nucleus.

2 stributed both at nerve terminals and in the cell nucleus.

3 it transports viral nucleic acid to the host cell nucleus.

4 arranged non-randomly in the 3D space of the cell nucleus.

5 of BRAT1 leads to BRAT1 trafficking into the cell nucleus.

6 by STRIDE and precisely localized within the cell nucleus.

7 cytotoxicity and localizes primarily in the cell nucleus.

8 e states of chromatin folding in the diploid cell nucleus.

9 syn also plays a gene-regulatory role in the cell nucleus.

10 n the case of the highly organized mammalian cell nucleus.

11 e the viral genome is maintained in the host cell nucleus.

12 C-terminal fragment that accumulates in the cell nucleus.

13 ation of misfolded proteins in the mammalian cell nucleus.

14 ere shown to strongly co-localize within the cell nucleus.

15 on that organizes functional elements in the cell nucleus.

16 ial for the exit of nascent capsids from the cell nucleus.

17 of current views on the organization of the cell nucleus.

18 ajor architectural elements of the mammalian cell nucleus.

19 form nucleosomes after release into the host cell nucleus.

20 espond to changes in the redox levels of the cell nucleus.

21 VirE2 and host VIP1 proteins--into the host cell nucleus.

22 t cell and are subject to degradation in the cell nucleus.

23 licated in a variety of functions within the cell nucleus.

24 which traffics from the vacuole to the host cell nucleus.

25 sion of the gene and its position within the cell nucleus.

26 the functional chromatin organization of the cell nucleus.

27 pots could be simultaneously located in each cell nucleus.

28 nd posttranscriptional activities within the cell nucleus.

29 toplasm and deposits the viral genome in the cell nucleus.

30 We report here that PKM2 localizes to the cell nucleus.

31 cription and replication of IAV occur in the cell nucleus.

32 ignal that directs macromolecules out of the cell nucleus.

33 nsis have been shown to localize to the host cell nucleus.

34 tioning of specific DNA sequences within the cell nucleus.

35 162 capsomers, and assembled in the infected cell nucleus.

36 ng egress of nucleocapsids from the infected cell nucleus.

37 cells and would traffic to the infected host cell nucleus.

38 cently reported to be translocated into host-cell nucleus.

39 r for delivering therapeutic agents into the cell nucleus.

40 for DNA in releasing activated STAT1 in the cell nucleus.

41 al cells with one to three traversals of the cell nucleus.

42 orce that attracts mRNA molecules within the cell nucleus.

43 gulating protein function, especially in the cell nucleus.

44 ear lamina, a structural scaffolding for the cell nucleus.

45 both modify important components of the host cell nucleus.

46 nd a subgroup of protein-coding mRNAs in the cell nucleus.

47 ed for the maturation of mRNA 3' ends in the cell nucleus.

48 vous system, often involve relocation of the cell nucleus.

49 lamellipodium from the cell periphery to the cell nucleus.

50 ed within the three-dimensional space of the cell nucleus.

51 is to provide structural scaffolding for the cell nucleus.

52 mmetric segregation of Ash1p to the daughter cell nucleus.

53 malian genome is highly organized within the cell nucleus.

54 AP/TAZ and prevent their accumulation in the cell nucleus.

55 of microRNA (miRNA) precursors in the plant cell nucleus.

56 re nonrandomly arranged within the mammalian cell nucleus.

57 tivity by controlling gene expression in the cell nucleus.

58 he non-heterochromatic subcompartment of the cell nucleus.

59 he spatial arrangement of genomes within the cell nucleus.

60 sids are able to deliver DNA to the infected cell nucleus.

61 introduce DSBs in a specified region of the cell nucleus.

62 accumulation of viral nucleocapsids in the T cell nucleus.

63 , c-Jun amino-terminal kinase and p38 in the cell nucleus.

64 r infectious genome and proteins to the host cell nucleus.

65 ibutes to the structural scaffolding for the cell nucleus.

66 ers ejection of the viral genome into a host cell nucleus.

67 led to phosphorylation of p68 at Y593 in the cell nucleus.

68 olar nuclei fuse to form the diploid central cell nucleus.

69 as been presumed to occur exclusively in the cell nucleus.

70 te to viscoelastic properties of the somatic cell nucleus.

71 initiate saltatory forward movements of the cell nucleus.

72 otein transport (T) complexes into the plant cell nucleus.

73 ajor architectural elements of the mammalian cell nucleus.

74 e visualised in cellular vacuoles and in the cell nucleus.

75 splicing, events that are restricted to the cell nucleus.

76 he 3D organization of chromosomes within the cell nucleus.

77 e spatial organisation of chromosomes in the cell nucleus.

78 n the accumulation of nucleocapsids in the T cell nucleus.

79 tly closed circular DNA (cccDNA) in the host cell nucleus.

80 hat occupies a substantial volume within the cell nucleus.

81 ent delivery of the viral genome to the host cell nucleus.

82 s and localize to a site just outside of the cell nucleus.

83 visualize these interactions in situ in the cell nucleus.

84 iated herpesvirus (KSHV) genomes in the host cell nucleus.

85 ent Binding Protein (STKR1) inside the plant cell nucleus.

86 rks mediate environmental information to the cell nucleus.

87 man genome into a roughly 10-micron-diameter cell nucleus.

88 rastic reorganization of domains in the host cell nucleus.

89 re similar in different locations around the cell nucleus.

90 lar deformability, a property limited by the cell nucleus.

91 lly regulated following delivery to the host cell nucleus.

92 after the viral genome has entered the host cell nucleus.

93 replication of the viral genome in the host cell nucleus.

94 cribed for sequencing the transcriptome of a cell nucleus.

95 ivity and increased p65 translocation to the cell nucleus.

96 nt Importins to import the histones into the cell nucleus.

97 s are chromatinized upon entry into the host cell nucleus.

98 ociated with HSV-1 genomes entering the host cell nucleus.

99 protein lost the ability to localize to the cell nucleus accurately.

100 , a class IIa HDAC that is exported from the cell nucleus after TCR engagement.

101 ed recombinant protein was able to enter the cell nucleus and activate HOXB4, a target gene of NF-Ya,

102 s expressing Pmk1 versions excluded from the cell nucleus and anchored to the plasma membrane in diff

103 erpesviral capsids are assembled in the host cell nucleus and are subsequently translocated to the cy

104 it lacking the 627 domain accumulates in the cell nucleus and assembles into a heterotrimeric polymer

105 Subsequently, Nrf2 translocates into the cell nucleus and binds to a cis-acting enhancer called t

106 s and exhibited impaired polarization of the cell nucleus and contractile cytoskeleton when compared

107 Molecular exchange between the cell nucleus and cytoplasm is one of the most fundamenta

108 sphorylation-dependent shuttling between the cell nucleus and cytoplasm, and interacts with gene-regu

109 atio of fluorescence intensities between the cell nucleus and cytoplasm.

110 upy differential radial positions within the cell nucleus and differentially associate with intranucl

111 preferred interactions with other CT in the cell nucleus and form preferred-albeit probabilistic-int

112 from being merely structural elements of the cell nucleus and has implicated them in novel cellular f

113 fering with the mechanical properties of the cell nucleus and how regulated actin polymerization play

114 is organized in three dimensions inside the cell nucleus and how this affects the ways in which cell

115 ong noncoding RNAs (lncRNAs) localize in the cell nucleus and influence gene expression through a var

116 likely occurs in close proximity to the host cell nucleus and involves the viral capsid.

117 ERbeta2 immunoreactivity is localized in the cell nucleus and is expressed with a distribution simila

118 of p115, endogenous CTF translocated to the cell nucleus and its nuclear import was required to enha

119 ignals with transcriptional responses in the cell nucleus and plays a critical role during T cell dev

120 e the mechanism of SKN-1 accumulation in the cell nucleus and provide a new mechanistic framework for

121 It largely localizes in the cell nucleus and regulates CD39 by interacting with nucl

122 ingle-stranded DNA and proteins--to the host cell nucleus and that a karyophilic protein carrier that

123 ule organizing center (MTOC) relative to the cell nucleus and the body axes, as a marker of cell pola

124 de range of biological processes in both the cell nucleus and the cytoplasm.

125 (NPC) is the gate for transport between the cell nucleus and the cytoplasm.

126 expressed and known to function in both the cell nucleus and the cytoplasm.

127 The global architecture of the cell nucleus and the spatial organization of chromatin p

128 NA) segments that are replicated in the host cell nucleus and transported to the plasma membrane for

129 proteins that are actively imported into the cell nucleus and visualization of their nuclear accumula

130 elomerase predominantly), accumulated in the cell nucleus, and caused DNA degradation.

131 tion of E2F3 and E2F4 with Trim28 within the cell nucleus, and co-immunoprecipitation assays demonstr

132 PcG proteins form condensates in the cell nucleus, and these condensates are the physical sit

133 smission then continues down to the level of cell, nucleus, and molecule; moreover, to lesser or grea

134 echanical stability and deformability of the cell nucleus are crucial to many biological processes, i

135 heterochromatin compartmentalization in the cell nucleus are elusive.

136 High levels of oligonucleotide in the cell nucleus are not a requirement for gene silencing, c

137 To test whether mechanical forces on the cell nucleus are relevant to NM ruptures in migrating ne

138 rtments of DNA viruses that replicate in the cell nucleus are so commonly found in association with N

139 dicate that radiation doses delivered to the cell nucleus are sufficient to kill cells of several dif

140 vated after viral genome entry into the host cell nucleus are the E1 and E4 units, which each express

141 e-dimensional organization of genomes in the cell nucleus arises from a wide range of architectural f

142 ellular S values in concentric and eccentric cell-nucleus arrangements and by comparing their dose-po

143 GFP-Wdr68 and RFP-Dyrk1a co-localized to the cell nucleus as expected based on the known sub-cellular

144 Nucleocapsids were located near the cell nucleus at early times postinfection (2 h) but were

145 proportion of cystatin D locates within the cell nucleus at specific transcriptionally active chroma

146 at some of the viral RNAs transcribed in the cell nucleus be exported to the cytoplasm without being

147 he viral RNA-dependent RNA polymerase in the cell nucleus before being exported to the cytoplasm for

148 herpesvirus, the viral DNA is present in the cell nucleus, but it is not extensively replicated or tr

149 n a highly ordered yet dynamic manner in the cell nucleus, but the principles governing this organiza

150 sed the intracellular milieu and entered the cell nucleus by a route that evaded pgp-mediated drug ex

151 teins, and the Gzms accumulate in the target cell nucleus by an unknown mechanism.

152 , Takifugu AID is actively exported from the cell nucleus by CRM1, and the Takifugu NES can substitut

153 Extracellular signals are transduced to the cell nucleus by effectors that bind to enhancer complexe

154 ger-electron-emitting radionuclides into the cell nucleus by means of nuclide-filled liposomes (Nucli

155 ricts unchromatinized DNA when it enters the cell nucleus by promoting the loading of nucleosomes and

156 enic induces the rapid reorganization of the cell nucleus by SUMO modification of nuclear body-associ

157 embrane and specifically target to the tumor cell nucleus by the changed permeability of the tumor ce

158 and mutated HMGN1 and HMGN2 proteins in the cell nucleus by using immunofluorescence studies, live c

159 Despite its size and rigidity, the cell nucleus can be moved or reorganized by cytoskeletal

160 Our findings reveal that the cell nucleus can be viewed as a highly charged polymer g

161 odel illustrates how dTMP synthesized in the cell nucleus can compensate for loss of intramitochondri

162 of transcription factor action in the living cell nucleus can provide important insights into gene re

163 The mechanical properties of the cell nucleus change to allow cells to migrate, but how c

164 The mammalian cell nucleus contains structurally stable functional com

165 We show that the cell nucleus contributes to the strength of the trap, wh

166 t an unanticipated role of cystatin D in the cell nucleus, controlling the transcription of specific

167 ray tomography reconstruction of an infected cell nucleus demonstrated that the peripheral, compacted

168 G, using a public 2D fluorescent dataset for cell nucleus detection and a 3D kidney magnetic resonanc

169 ed with VEGF, SETSIP was translocated to the cell nucleus, directly bound to the VE-cadherin promoter

170 positioning of chromosomes and genes in the cell nucleus, distinct chromatin compartments, and topol

171 st and replicate as episomes inside the host cell nucleus during latent infection.

172 ranscripts that are exported from the mother-cell nucleus during mitotic anaphase, transported to the

173 We report that HDAC7 is exported from the cell nucleus during positive selection in mouse thymocyt

174 ear localization signals (NLSs) to enter the cell nucleus during ribosome assembly.

175 e we report that Rgf1p is relocalized to the cell nucleus during the stalled replication caused by hy

176 trafficking of papillomaviruses to the host cell nucleus during their natural infectious life cycle

177 pel-like factor 6 (KLF6) translocates to the cell nucleus during wound healing, concomitantly with an

178 essential for many crucial functions in the cell nucleus (e.g., DNA replication and mitotic spindle

179 nteracted with histone H3 and IKKbeta in the cell nucleus, enhancing histone H3 phosphorylation throu

180 internalization, though DF did not reach the cell nucleus even after 24 hours.

181 Calcium transients in the cell nucleus evoked by synaptic activity in hippocampal

182 In conclusion, Dm-dNK expression in the cell nucleus expanded the total dNTP pools to levels req

183 herpes simplex virus type 1 (HSV-1)-infected cell nucleus, foci enriched in the Hsp70/Hsp40 chaperone

184 o deliver their RC DNA content into the host cell nucleus for conversion to the covalently closed cir

185 T) has been scored from energy deposits in a cell nucleus; for very low-energy ions, it has been defi

186 of histone demethylation enzymes within the cell nucleus, formaldehyde is produced endogenously, in

187 Inside the cell nucleus, genomes fold into organized structures tha

188 ion with microscopy imaging data for various cell nucleus geometries (lymphoblastoid, skin fibroblast

189 merging role of cytoskeletal proteins in the cell nucleus has become a new frontier in cell biology.

190 the physiological function of CD40 in the B-cell nucleus has not been examined.

191 accumulation of the pristine material in the cell nucleus; however, CePO(4) was found(.) The presence

192 hly enriched in a non-nucleolar locus in the cell nucleus implicated in SL RNP biogenesis.

193 AIF translocates to the host cell nucleus, implying that it has a crucial role in Omp

194 med to assess self- and cross-doses for each cell nucleus in a population of 10(6) cells.

195 is highly conserved enzyme is located in the cell nucleus in all vertebrates investigated to date, bu

196 ted cells, chromosomes are packed inside the cell nucleus in an organised fashion.

197 Herpesvirus nucleocapsids exit the host cell nucleus in an unusual process known as nuclear egre

198 elocation of beta-catenin to the endothelial cell nucleus in CM.

199 Our findings reveal a role of the cell nucleus in harboring RNA molecules that are not imm

200 w that the calcium buffering capacity of the cell nucleus in mouse hippocampal neurons regulates neur

201 vation and limited fragmentation of the host cell nucleus in response to agonists that induce apoptos

202 iquitinated proteins occurs primarily in the cell nucleus in transfected cells and requires intact UI

203 tagged IQD1 proteins to microtubules and the cell nucleus in transiently and stably transformed plant

204 e protein, ASP, of HIV-1 is found within the cell nucleus in unstimulated cells.

205 ent architectural remodeling of the neuronal cell nucleus in vivo contributes to activity-dependent c

206 of discrete compartments within the infected-cell nucleus in which replication proteins are concentra

207 d that the BAFF-R protein was present in the cell nucleus, in addition to its integral presence in th

208 aspase that is present constitutively in the cell nucleus, in addition to other cellular compartments

209 (HSV-1) induces profound modification of the cell nucleus including formation of a viral replication

210 at Rrp6 and Rrp47 are localized to the yeast cell nucleus independently of one another.

211 sults in retention of poly(A)(+) RNAs in the cell nucleus, indicating that NPM1 influences mRNA expor

212 roxyl radical and peroxynitrite close to the cell nucleus, inflicting DNA damage, but the source of r

213 signaling, beta-catenin translocates to the cell nucleus, interacting with Tcf/Lef factors to activa

214 ophilum, which is translocated into the host cell nucleus, interacts with gene regulatory regions of

215 d to the release of ssDNA fragments from the cell nucleus into the cytosol, engaging this innate immu

216 tial for successful reprogramming of somatic cell nucleus into the pluripotent state.

217 Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation

218 The cell nucleus is a compartment in which essential process

219 Gene transcription in the cell nucleus is a complex and highly regulated process.

220 The mammalian cell nucleus is a dynamic and highly organized structure

221 The cell nucleus is a highly organized structure and plays a

222 The cell nucleus is a remarkably well-organized organelle wi

223 The mammalian cell nucleus is compartmentalized into nonmembranous sub

224 In vivo, the cell nucleus is frequently subjected to deformation on a

225 The composition of the cell nucleus is highly heterogeneous, with different con

226 nscriptional gene silencing in the mammalian cell nucleus is less understood.

227 Delivery of the viral DNA into the host cell nucleus is necessary for establishment of infection

228 idence that transcription in the presynaptic cell nucleus is not necessary for this form of plasticit

229 organization of chromatin in the eukaryotic cell nucleus is of vital importance for transcription, D

230 mponent of the T-complex and localize to the cell nucleus is sufficient for transient genetic transfo

231 that with successful targeting to the tumor-cell nucleus it is possible to obtain a therapeutic effe

232 AGT variant that fails to accumulate in the cell nucleus (K125L), suggesting that nuclear DNA damage

233 n asymmetric perinuclear region (outside the cell nucleus) known as the microtubule organizing center

234 (HSV) dramatically reorganizes the infected-cell nucleus, leading to the formation of prereplicative

235 adiation induced early DNA damage on a naked cell nucleus model.

236 The cell nucleus must continually resist and respond to inte

237 Immunoreactive APOBEC2 was localized to the cell nucleus of developing myocardium and skeletal myofi

238 which themselves reside within almost every cell nucleus of eukaryotic organisms.

239 n the cytosol but are also detectable in the cell nucleus of hippocampal neurons, suggesting that nuc

240 babilistic non-random arrangement within the cell nucleus of mammalian cells including radial positio

241 e, we explore the effects of crowding in the cell nucleus on a model of gene transcription as a netwo

242 dynamic organization of chromatin inside the cell nucleus plays a key role in gene regulation and gen

243 e three-dimensional (3D) architecture of the cell nucleus plays an important role in protein dynamics

244 hus indicating its function within the plant cell nucleus, possibly by binding naked T-strands and bl

245 The mammalian cell nucleus provides a landscape where genes are regula

246 rs and/or chromatin-modifying enzymes in the cell nucleus, rather than their role in Golgi fission, w

247 Calcium (Ca(2+)) signaling within the cell nucleus regulates specific cellular events such as

248 to induce damage in a defined region in the cell nucleus, representing an innovative technology to e

249 Up to 40% of spectra from the cell nucleus show Raman bands associated with nanopartic

250 n of spectra, classified as belonging to the cell nucleus, show Raman bands associated with nanoparti

251 ion of chromatin in crucial processes of the cell nucleus such as transcription regulation.

252 he distribution of DNA damage throughout the cell nucleus, suggesting implications for DNA repair fid

253 However, CaBPs are also expressed in the cell nucleus, suggesting that they modulate nuclear calc

254 o self-assembly achieved for the oncotropic, cell nucleus-targeted MVM capsid may facilitate its deve

255 s, we introduce a computational model of the cell nucleus that explicitly includes chromatin fibers,

256 in has a complex spatial organization in the cell nucleus that serves vital functional purposes.

257 These data suggest that in the cell nucleus the presence of negatively charged DNA or R

258 pect to the total number of nucleosomes in a cell nucleus, the accessibility of the transcription fac

259 lating NF-kappaB translocation into the host cell nucleus, the data collectively suggest that a profo

260 However, after entry into the infected cell nucleus, the HSV genome begins to associate with nu

261 In the plant cell nucleus, the RRS1-R/RPS4 complex binds to and signa

262 articles can easily enter cells and even the cell nucleus, these data provide evidence that ultrasmal

263 S can target a heterologous protein into the cell nucleus through interactions with Kap104p.

264 main (CX3CL1-ICD) would translocate into the cell nucleus to alter gene expression due to this back-s

265 predicts the shear-induced deflection of the cell nucleus to be 0.87 +/- 0.03 microm.

266 end causes the first gene to enter the host cell nucleus to be alpha4, a transcription factor requir

267 lease RC DNA (i.e., uncoating) into the host cell nucleus to form the covalently closed circular (CCC

268 is unknown how BRAT1 is trafficked into the cell nucleus to maintain ATM phosphorylation.

269 rnatively, can deliver their DNA to the host cell nucleus to maintain the viral genome as nuclear epi

270 mobilization of activating proteins into the cell nucleus to repair damaged DNA.

271 Export of mRNA from the cell nucleus to the cytoplasm is essential for protein s

272 paBalpha) promotes NF-kappaB export from the cell nucleus to the cytoplasm, but the physiological rol

273 dy linked to various cancers-moving from the cell nucleus to the cytoplasm.

274 plicate the viral RNA genome within the host cell nucleus, to evade host restriction factors and inna

275 s a severe displacement of the photoreceptor cell nucleus toward the synaptic terminus.

276 all three SRC-RIDs, measured throughout the cell nucleus, transitioned from structurally similar, hi

277 l function, more than 98% are encoded in the cell nucleus, translated in the cytoplasm, sorted based

278 It is now evident that the cell nucleus undergoes dramatic shape changes during imp

279 ly endosomes and appears additionally in the cell nucleus upon continuous EGF stimulation.

280 y nanotubes, the oligos can translocate into cell nucleus upon endosomal rupture triggered by NIR las

281 translocates from the plasma membrane to the cell nucleus using a microtubule-dependent shuttle that

282 trix metalloproteases and transferred to the cell nucleus via endosomes and the cytoplasm.

283 tes from protein-DNA interactions within the cell nucleus we have investigated the initial cellular r

284 When foci are reconstructed in the whole cell nucleus, we obtain information on damage characteri

285 acellular parasites and traffics to the host cell nucleus where it inhibits STAT1-dependent proinflam

286 Yet PTEN can also localize to the cell nucleus where its functions remain unclear.

287 ther show that this process is active in the cell nucleus, where another system for aggregate clearan

288 ctor 1 receptor (IGF-1R) translocates to the cell nucleus, where it binds to enhancer-like regions an

289 ded transferred DNA (T-strand) into the host cell nucleus, where it can be converted into double-stra

290 e cytoskeleton, actin is also present in the cell nucleus, where it has been linked to many processes

291 at, upon DNA damage, WWOX accumulates in the cell nucleus, where it interacts with ATM and enhances i

292 nscription (TgIST), translocates to the host cell nucleus, where it recruits Mi-2/NuRD to STAT1-depen

293 ptor (AhR), causing it to translocate to the cell nucleus, where it transactivates target genes.

294 revealed that UNC45A localizes to the cancer cell nucleus, where it up-regulates the transcriptional

295 n without inhibiting forward movement of the cell nucleus, whereas local treatment posterior to the n

296 led to a build-up of HDAC4 and HDAC5 in the cell nucleus, which in the case of PV.NLS-mC can be reve

297 NE defines the shape and size of the cell nucleus, which increases during the cell cycle, acc

298 ), a poorer WWP1 substrate, was found in the cell nucleus, while WWP1 was not.

299 r final destinations by translocation of the cell nucleus within their leading process and immature b

300 s to a dynamical compartmentalization of the cell nucleus, yet the mechanisms by which interphase chr