ライフサイエンスコーパス: cell population

1 ng mutant cells demonstrates no loss of stem cell population.

2 aptive resistance development in an isogenic cell population.

3 and equilibrium convergence of the cultured cell population.

4 ymbionts significantly decreases this T(reg) cell population.

5 all DNA replication initiation events in any cell population.

6 c points during S phase using a synchronized cell population.

7 ntribute to the endocytic heterogeneity of a cell population.

8 nonrecirculating lung-resident gammadelta T cell population.

9 hibitory pathway for this immunoregulatory T cell population.

10 partner in the maintenance of an adult stem cell population.

11 adult stages exclusively in a skeletal stem cell population.

12 expressing myofibroblasts, a key profibrotic cell population.

13 mice resulted in further expansion of the DR cell population.

14 n plasma, and a long-lasting CD11b(+)CD16(+) cell population.

15 he metabolic requirements of the cancer stem cell population.

16 stochastically throughout the epidermal stem cell population.

17 own adipocytes are composed of a homogeneous cell population.

18 o chemotherapy, and restricted the TNBC stem cell population.

19 is, counting however for only 11% of newborn cell population.

20 fects commonly measured cytokines and immune cell populations.

21 recovering novel transcriptionally distinct cell populations.

22 strategy for stimulating antigen-specific T cell populations.

23 lymph nodes associated with differences in T cell populations.

24 lower in mitosis than in G2 in synchronized cell populations.

25 ed gene expression in specific developmental cell populations.

26 ) sequencing reveal lineage connections in T cell populations.

27 3B loss influences specific subsets of these cell populations.

28 rns of differential gene expression in glial cell populations.

29 ne expression, even in otherwise homogeneous cell populations.

30 tified within effector, but not regulatory T-cell populations.

31 dout of activity from genetically identified cell populations.

32 tic alterations in colorectal cancer stromal cell populations.

33 en species, and the human juvenile and adult cell populations.

34 static tumors, generating heterogenous tumor cell populations.

35 e organs, such as tissue samples or isolated cell populations.

36 or by mediating off-target effects on immune cell populations.

37 tumor-on-a-chip platform involving different cell populations.

38 ntamination of transcripts between different cell populations.

39 alient biological features captured by small cell populations.

40 les are ligands for several unconventional T cell populations.

41 between the germline and supporting, somatic cell populations.

42 membrane potential changes measured in bulk cell populations.

43 es, a common model for asexually reproducing cell populations.

44 n and tracking of clonal and subclonal tumor cell populations.

45 ses at single-cell resolution within complex cell populations.

46 election, and reprogramming of heterogeneous cell populations.

47 al approach, over- or underrepresent certain cell populations.

48 study interactions between microbes and tuft cell populations.

49 ance of extraordinarily large CMV-specific T cell populations.

50 ived from tissues possessing motile ciliated cell populations.

51 ances the performance between major and rare cell populations.

52 l characteristics observed in many migratory cell populations.

53 f cellular plasticity in multiple non-acinar cell populations.

54 fy TSPO protein in neuronal and non-neuronal cell populations.

55 markedly decreasing premalignant B lymphoid cell populations.

56 ctuations of local excitatory and inhibitory cell populations.

57 s retention of methylated histone in a sperm cells population.

58 The cell population abundances were quantified using the mic

59 tensive regional specialization of principal cell populations across the length of the epididymis.

60 ylogenetic algorithm to infer how associated cell populations adapt across the metastatic transition

61 Here, we reveal TAD features inaccessible to cell population analysis by using super-resolution micro

62 moke exposure triggers the expansion of this cell population and a concomitant increase in ACE2 expre

63 werful tool to identify both common and rare cell population and can handle large dataset.

64 ssure value above which a sudden decrease in cell population and cell membrane damage have been obser

65 central and terminally differentiated memory cell population and increased ICOS and BCL6 expression w

66 f psoriasis linked to a reduced regulatory T cell population and increased IL-17A expression in gamma

67 ells goes beyond its ability to expand the B cell population and is additional to the BAFF-independen

68 y enhance the chondrogenicity of the overall cell population and offers a platform to further elucida

69 d upstream of PLT1/PLT2 to modulate the stem cell population and primary root growth in Arabidopsis.

70 nstruct a detailed, high-resolution atlas of cell populations and assess variability in cell composit

71 halamus is composed of many neuropeptidergic cell populations and directs multiple survival behaviors

72 et principle applied to the aging of somatic cell populations and discuss the implications for unders

73 Blood cell populations and ex vivo innate whole blood cytokine

74 etains target protein dosages in gene-edited cell populations and expands gene editing to chromosomal

75 of chronic cholestasis reduces DR-cell and B-cell populations and hepatic fibrosis.

76 a unique tool for manipulating input-defined cell populations and mapping their outputs.

77 ts the interactions between tumor and immune cell populations and reveals how variation in patient re

78 omoters shape latent HSV-1-specific CD8(+) T cell populations and should be an important consideratio

79 the genetic programs of distinct lung T(RM) cell populations and show that local environmental cues

80 Evidence in cell populations and single cells indicates that scaling

81 rta with gene expression profiling of sorted cell populations and single cells.

82 l HLA-A*01:01-restricted EBV-LMP2-specific T-cell populations and TCRs, which can potentially be used

83 preferentially predicting homogenous cancer cell populations and those using MuTect tending to predi

84 ional skin has led to knowledge of important cell populations and transcriptional changes contributin

85 ied on a node-centric network model in which cells, populations and regions are linked to one another

86 rogeneities in migratory phenotypes within a cell population, and for the targeted enrichment of the

87 in mean tumor volume, increase in the CD8 T-cell population, and immune activated gene signaling.

88 arkers of atopy, type 2 inflammation, immune cell populations, and cytokines.

89 y of the memory B cell and long-lived plasma cell populations are not fully elucidated.

90 are delineating how protective memory CD8 T cell populations are primed and maintained and how such

91 arge-scale studies of natural and engineered cell populations as they respond to drugs, signals, or p

92 ncers, individual cancer cases and different cell populations, as well as crosstalk between pathways,

93 However, most current assays report cell population averages and are mostly time endpoint me

94 lls align closely with conventional memory T cell populations, bearing little resemblance to recently

95 engager leads to changes in the host myeloid cell population, both of which contribute to treatment i

96 Image analysis of motile cell populations, both primary and cultured, typically r

97 o effectively isolate cells of interest from cell populations but also enable more precise sample sel

98 Stratifying each sinusoidal cell population by activation state, we projected shifts

99 indicate that following MF, a resident stem-cell population can be induced to generate cartilage for

100 p3(+) regulatory T cells (T(regs)) are a key cell population capable of facilitating durable immune t

101 terleukin-18 (IL-18) selectively expands a T-cell population (CD4+CD45RO+PD-1(hi)ICOS+CCR2+CXCR5-) di

102 ncing (scRNA-seq) is invaluable for studying cell populations, cell-surface proteins are often integr

103 animal cell types demonstrate that within a cell population, cellular proliferation is low for small

104 ha-synuclein aggregates appeared in infected cell populations connected to the olfactory bulbs follow

105 We further show that multiple immune cell populations contain lineage-labeled particles, sugg

106 s were quantified using the microenvironment cell population-counter package and compared with immuno

107 A PBG cell population (Cytokeratin19(-) /SOX9(+) ) is involved

108 Specifically, Tbx5 deletion in this cell population decreased cell apoptosis and increased t

109 lls revealed 20 neuronal and 18 non-neuronal cell populations, defined by suites of discriminatory ma

110 pigenetic effects of PADI4 on the bulk tumor cell population did not explain the CSC phenotype.

111 (+)CD206(-)): a transitional CD11c(+)CD16(+) cell population directly associated with IL-6 levels in

112 cosystem.Objectives: We aimed to investigate cell population distributions and transcriptional change

113 In direct contrast, the splenic PtC(+) B-1a cell population does not preserve its IgM germline statu

114 signs of rapid proliferation in the human T cell population during the first 1-3 wk posttransplant a

115 letal trauma, the inflammatory responses and cell population dynamics that regulate subsequent wound

116 ular traits exhibited by genetically diverse cell populations enables in vitro systems genetics appro

117 e fate of the recently described adaptive NK cell population, endowed with increased ability to media

118 anisms including maintaining the cancer stem cell population, enhancing DNA damage repair, facilitati

119 hydrocortisone and cholera toxin shifted the cell population equilibrium toward stem-like or non-stem

120 mulus sensitivity and information encoded in cell populations, even though animals are unaware of sti

121 mentation includes delivery of combinatorial cell populations exerting synergistic effects.

122 werful proxies for difficult to obtain human cell populations, facilitating the illumination of commo

123 Correlation of immune-cell population frequencies with treatment response, pro

124 ely resolve novel transcriptionally coherent cell populations from an intuitive graphical user interf

125 tablishing an efficient method for surveying cell populations from large experiments or clinical samp

126 expression was determined in wild-type lung cell populations from three independent research groups.

127 ation, and modulation of specific effector T cell populations generated in the immediate wake of an a

128 ed, and a specific disease-promoting myeloid cell population has not been identified.

129 xpansion in regenerating haematopoietic stem cell populations has recently been associated with both

130 , the path toward endogenous renewal of beta-cell populations has remained elusive.

131 tion of epitope promoter influences CD8(+) T cell population hierarchies and their function.

132 alpha/beta pathway in different CNS resident cell populations implicate complex cooperative pathways

133 ed alveolar macrophages (Mo-AMs), which is a cell population implicated in murine models of pulmonary

134 cells represent a metabolically active lung cell population important for surfactant biosynthesis an

135 Genetic ablation of POLR1A-high cell population imposes an irreversible growth arrest on

136 gical approaches to identify a CD69(+) CD4 T cell population in both the mouse and human brain, disti

137 he number of T helper 17 cells, a pathogenic cell population in EAE.

138 ereas ILCregs are not a generalizable immune cell population in mice.

139 lta2 cells, the most abundant TCR gammadelta cell population in peripheral blood.

140 ly within the spermatogonial stem/progenitor cell population in postnatal testis.

141 nhibitor effectively to the cancer stem-like cell population in SHH MB.

142 lonal antibodies, we directly identified a T cell population in the alpaca (Vicugna pacos), which res

143 mma9Vdelta2 T cells are a major gammadelta T cell population in the human blood expressing a characte

144 aken together, our studies identified a stem cell population in the JE and have potential clinical im

145 and changes in the composition of the immune cell population in the left ventricle manifested by lowe

146 The expanded DR cell population in Tr(-/-)Mdr2(-/-) mice was due to decr

147 y modulate peripheral immune and endothelial cell populations in a highly context-dependent manner.

148 spreading of a cell swelling effect through cell populations in a lipid peroxide- and iron-dependent

149 lity and provided both enriched and depleted cell populations in a single sort.

150 erroptosis has the ability to spread through cell populations in a wave-like manner, resulting in a d

151 8 T cells form prominent and separate immune cell populations in atherosclerotic aortas.

152 s expressed in multiple stem/progenitor-like cell populations in both the normal prostate epithelium

153 t specific mutations seem to modulate immune cell populations in ccRCC tumours.

154 comprehensive single-cell analysis of immune cell populations in colitis, a common and severe side ef

155 ous promise in reproducibly resolving hidden cell populations in complex datasets.

156 ntify the role of the different neural crest cell populations in distal gut innervation, and conseque

157 t subsets of chemoresistant tumor-initiating cell populations in diverse human malignancies.

158 with cytomegalovirus, which elicits large T cell populations in humans and mice.

159 ifically reducing cytokine-producing myeloid cell populations in Irf5 (-/-) mice but not impacting ty

160 is required for the maintenance of mature B cell populations in mice.

161 fluence of RBPs on the biology of progenitor cell populations in other lineages.

162 First, we tracked congenically marked OT-I cell populations in recipient mice infected with murine

163 sion profiles and anatomical locations of 58 cell populations in the human lung, including 41 out of

164 The existence of "active" and "reserve" stem cell populations in the intestinal epithelium has been d

165 systematically classify molecularly distinct cell populations in the mouse VPH.

166 ll comparators, as well as from gammadelta T cell populations in the mouse.

167 y (CyTOF) to characterize and compare immune cell populations in the mucosa and blood from patients w

168 After gastrulation, when similar muscle cell populations in the post-anal tail are generated fro

169 guished from gastrulating and extraembryonic cell populations in the primate embryo.

170 Conventional CD4(+) T cell populations in thymus, blood, and spleen of MHCIIKR

171 sequencing (scRNA-seq) resolves heterogenous cell populations in tissues and helps to reveal single-c

172 tically, stimulation of specific bone marrow cell populations in vivo using growth factor pharmacothe

173 sible to visualize antigen-specific CD8(+) T-cell populations in vivo, which may serve prognostic and

174 erogeneity of olfactory sensory neuron (OSN) cell populations in wild-type (WT) mice, and revealed th

175 an effectively transduce a variety of immune cell populations including CD4(+) T cells, CD8(+) T cell

176 therapeutic routes for heterogeneous cancer cell populations, including CSCs.

177 e histone methylation signatures in affected cell populations, including repressive H3K9me3 and H3K27

178 e adult schistosome and identify 68 distinct cell populations, including specialized stem cells that

179 iR-155 promotes the activation of effector T cell populations, including T follicular helper cells, a

180 trol individuals, and expressed by several T-cell populations, including T-helper type 2 cells.

181 By day 7, the ocular T cell population increases to 50% of CD45 + cells, leadin

182 id progenitors (AMPs), a leukemia-initiating cell population induced by Cbfb-MYH11 in the bone marrow

183 respond to both rate and timing of Purkinje cell population inputs, whereas GABAergic-like neurons o

184 Transplantation of hPSC-derived cell populations into preclinical models has generated t

185 creased the differentiation of other CD34(+) cell populations into the NK lineage in a non-contact de

186 Thus, CD8(+) T cell-population-intrinsic mechanisms regulate cellular b

187 er small but biologically interesting immune cell populations invisible to analysis of the full data.

188 metastatic tumor cells from a heterogeneous cell population is a daunting challenge.

189 dentifying resident or donor stem/progenitor cell populations is crucial for augmenting the low intri

190 Rapid analysis of single and scant cell populations is essential in modern diagnostics, yet

191 ion and spatial organization of intratumor T-cell populations is prognostic in some cancer types.

192 tion of bulk transcriptomics data from mixed cell populations is vital to identify the cellular mecha

193 We performed RNAseq of cell populations isolated using laser capture microdisse

194 cation of this platform enabled the study of cell-population kinetics of infection and cell death by

195 ncer hubs impinging on MYC detected in large cell populations likely do not exist in single cells.

196 al crest (NC) cells, a highly migratory stem cell population likened to invasive cancer cells, as a m

197 deletion of TRAIL receptor increased the DR cell population, macrophage accumulation, and hepatic fi

198 These recovered cell populations maintained the viral genomes in a quies

199 nterest in understanding how the cancer stem cell population may be maintained in solid tumors.

200 vation suggests that the magnitude of the DR-cell population may be regulated by apoptosis.

201 Through this ongoing process, certain cell populations might have gained growth advantage or m

202 These data provide a new three-cell population model that both orders critical GC funct

203 a Blimp1(hi)Id3(lo) tissue-resident effector cell population most prominent in the early phase of acu

204 an effective method of targeting the immune cell populations most relevant for antitumoral immunity

205 formation on the chromatin organization in a cell population, namely the contact count between any se

206 We show here that expansion of the infected cell population, observed in LECs, but not in blood endo

207 nd to identify molecular alterations in each cell population of human ATAA tissues.

208 ategies that specifically modulate different cell populations of the TME, such as targeting pericytes

209 brosis, and the relative effect of disparate cell populations on cardiac fibrosis, remain unclear.

210 are initiated from a leaf axil meristematic cell population originally detached from the shoot apica

211 local blood supply but can also occur where cell populations outgrow the local vasculature, as obser

212 However, the molecular signatures of immune cell populations over time in an autoimmune process rema

213 However, in sorted tumor cell populations, PADI4 downregulated expression of mast

214 , as the pregnancy progress, in terms of the cell population, phenotype and production of immune fact

215 In plants and animals, self-renewing stem cell populations play fundamental roles in many developm

216 eeking by different MMP subtypes on distinct cell populations poses MMP-2,9 activity as an important

217 sharing of TCR clonotypes between these Treg cell populations, potentially denoting a common progenit

218 pressing bioactive TGFbeta in fibroblasts, a cell population present in the microenvironment of almos

219 has enabled detailed characterization of the cell populations present in small biopsy samples of kidn

220 /-) versus Mdr2(-/-) mice, suggesting the DR cell population promotes macrophage-associated hepatic i

221 While analyses of cell populations provide averaged information about vira

222 Growth laws emerging from studies of cell populations provide essential constraints on the gl

223 er demonstrate that Bax acts via the bipolar cell population, rather than cell-intrinsically, to cont

224 ion; however, genetic alterations in stromal cell populations remain largely unexplored.

225 ut the identity of the equivalent human stem cell population remains unknown owing to a lack of surfa

226 g modules activated by radiation in specific cell populations reshape the immunological tumor microen

227 ly to the latter, we tested whether isogenic cell populations respond in a non-uniform manner by stud

228 Specifically, an early-life precursor cell population, retained in the mouse cortex postnatall

229 oiesis and transcriptome analysis of HSC/GMP cell populations revealed enrichment of neutrophil- and

230 arative evaluation of proximal and distal TE cell population's shows heightened inflammatory signalin

231 l communication modeling suggests that basal cell populations serve as crucial signaling hubs to main

232 The potential of diverse cell populations serving as a reserve source for acini w

233 stream cellular processes, between different cell populations, should be taken into account.

234 Manipulations of different cell populations showed that multiple sets of peptidergi

235 as a tripartite radial stratification, each cell population showing a characteristic molecular profi

236 e were able to identify a CD27- CD94+ CD8+ T cell population significantly associated with latent CMV

237 Within these GSCs, we identify an invasive cell population similar to outer radial glia (oRG), a fe

238 bone-marrow-associated, radiation-sensitive cell population, since long-bone removal or pre-transpla

239 gonists modulates innate and adaptive immune cell populations skewing their polarization toward a mor

240 nity is driven by transcriptionally distinct cell populations specialized in divergent biological fun

241 udy, we found that polyclonal naive murine B cell populations specific for a variety of foreign Ags e

242 single-cell technologies to identify immune cell populations specific to mucosa and blood samples fr

243 perturbation experiment revealed changes in cell population structure and transcriptional states tha

244 Moreover, specific ablation of primary T(RM) cell populations substantially impaired the secondary T

245 onset of periodontal development, progenitor cell populations such as dental follicle cells are chara

246 acellular signals induce distinct ectodermal cell populations, such as the neural crest and the neura

247 modules that are correlated with alternative cell populations, suggesting collaborative interactions

248 mmon core characteristics of all CD21(low) B cell populations suggests either a common ancestry or a

249 MEndoT-derived cells are an endothelial-like cell population that can be regulated to treat cardiac h

250 ntiation of physiological functions across a cell population that confers survival benefits; among un

251 STDC1-expressing T(FH) cells as a distinct T cell population that develops after SOSTDC1(-) T(FH) cel

252 population or are instead a remnant effector cell population that failed to undergo initial contracti

253 developed tumors composed of a heterogenous cell population that resembled that seen in primary NBs

254 with a depleted and exhausted CD4 and CD8 T-cell population that resides within a heavily hyperinfla

255 T cells are a major human blood gammadelta T cell population that respond in a T cell receptor (TCR)-

256 oportions of the circulating GZMK(+)CD8(+) T cell population that shares transcriptional and epigenet

257 c neural crest cells (cNCCs) are a migratory cell population that stem from the cranial portion of th

258 entified a persisting antigen-specific CD8 T cell population that was terminally fated with potent ef

259 plex biology, revealing the behavior of rare cell populations that are masked in bulk population anal

260 Despite this, transcriptional definition of cell populations that comprise both the medial habenular

261 Hydra possesses three distinct stem cell populations that continuously self-renew and preven

262 rdiac cellular landscape uncovering multiple cell populations that contribute to pathological remodel

263 fferentiation events producing heterogeneous cell populations that display mixed pancreatic islet phe

264 onal heterogeneity and shed new light on the cell populations that largely define cytokine and chemok

265 While CDCP1 expression identifies stem cell populations that mediate lung metastasis, mechanism

266 system, and here, mainly towards specific T-cell populations that promote homeostasis.

267 unctionality of these mesenchymal progenitor cell populations that regulate tooth eruption and tooth

268 pletely independent and non-cross-reactive T cell populations that show distinct functional character

269 racterize these abortive cells, we recovered cell populations that survived infection with HSV-1 at h

270 stic way), the interaction between different cell populations, the custom design of the cell cycle an

271 The isolation of a single skeletal stem cell population through cell surface markers and the dev

272 We found HDC-positive cell populations throughout the CNS, including the optic

273 ified and located in situ CD8alphaalpha(+) T cell populations, thymic fibroblast subtypes, and activa

274 nvestigate potential mechanisms linking this cell population to CVD.

275 elucidating the contributions of individual cell populations to embryonic development and tissue reg

276 ogeneity of circadian oscillations in clonal cell populations to investigate the underlying mechanism

277 ld mimics the cartilage niche, allowing both cell populations to maintain their stem cell features an

278 Raman to the detection of the parasite in a cell population using ATR-FTIR for a babesiosis diagnost

279 emerges in the total response of the Kenyon cell population using multiple odor-specific features of

280 CSCs were isolated from pancreatic cancer cell populations using flow cytometry and characterized

281 This NK cell population was also detected in the circulation of

282 DR cell population was greatly expanded in the Tr(-/-)Mdr2(

283 Within the endothelial cell population, we defined subsets with angiogenic capa

284 rmation and ganglionic retention of CD8(+) T cell populations, we developed recombinant HSV-1 with th

285 better characterize these different myeloid cell populations, we used long-term in vivo 2-photon mic

286 effects on the phenotype of the total CD8 T-cell population were apparent only in HLA-B*57-negative

287 Three distinct cell populations were identified: inflammatory, fibrobla

288 Cord blood regulatory T-cell populations were measured at birth.

289 generate and maintain inflationary CD8(+) T cell populations, which are counterintuitively short-liv

290 recruit neurons across multiple hypothalamic cell populations, which cooperatively drive robust defen

291 results in heterogeneity in the female germ cell populations, which limits the studies of meiosis in

292 Asymmetric divisions maintain long-term stem cell populations while producing new cells that prolifer

293 We observe a cell population with a skeletal muscle signature in etv2

294 ct ProSG cell subsets, including a migratory cell population with a transcriptome distinct from the p

295 helial lymphocytes (IELs), a heterogeneous T cell population with cytotoxic and regulatory properties

296 Furthermore, a rare cell population with monocyte-like transcriptional featu

297 support the existence of a platinum-tolerant cell population with partial cancer stem cell features,

298 ation structure of multiple clones (infected cell populations with identical genomic proviral integra

299 ide insights into the interactions of immune cell populations with neighbouring epithelial and endoth

300 the bone marrow-resident, long-lived plasma cell population, yet absence of this kinase led to incre