ライフサイエンスコーパス: cell volume

1 constraint and ignores potential changes in cell volume.

2 ng approximately 5-fold variation in average cell volume.

3 selection to evolve a 9.3-fold difference in cell volume.

4 increased nutrient supply results in larger cell volume.

5 xceeds that of a smooth sphere enclosing the cell volume.

6 e size is positively correlated with the egg cell volume.

7 n either corrective or pathologic changes in cell volume.

8 s ("popping"), without detectable changes in cell volume.

9 n essential adaptive mechanism for restoring cell volume.

10 rough 140 K, with a 23 % contraction in unit cell volume.

11 ock, and that cell shape recovers along with cell volume.

12 hormogonia might be accelerated by reducing cell volume.

13 ce cellular water and solute homeostasis and cell volume.

14 ta-cell insulin secretion and decreased beta-cell volume.

15 t in response to an osmotic gradient changes cell volume.

16 ins do not uniformly decrease but scale with cell volume.

17 ells were also examined to assess changes in cell volume.

18 raction is captured by rescaling the average cell volume.

19 et size without enlarging cytoplasmic and/or cell volume.

20 ntrol and scaling of centrosomes relative to cell volume.

21 to increase oxygen carrying capacity and red cell volume.

22 namics on the order of one second per single-cell volume.

23 regulate intracellular pH, sodium levels and cell volume.

24 myofibrils comprising the bulk of the muscle cell volume.

25 tes significantly scale sublinearly with the cell volume.

26 PDZ-binding motif) are regulators of single-cell volume.

27 c ( P21/ n), as well as an expansion of unit cell volume.

28 he anterior-posterior variation in notochord cell volume.

29 exhibit a constant ratio between nuclear and cell volume.

30 age-associated decrease in surface area per cell volume.

31 the changed membrane potential is to adjust cell volume.

32 trations as they accumulate in proportion to cell volume.

33 zed by electron microscopy and a decrease in cell volume.

34 egulate intracellular pH, sodium levels, and cell volume.

35 aberrant numbers of centrosomes and altered cell volumes.

36 family, PST-20 and PST-25, with much larger cell volumes (166,988 and 275,178 cubic angstroms, respe

37 ry low symmetry (triclinic) and a large unit cell volume (1874.6 A(3)), containing 16 silicon and 32

38 These two zeolites have much larger unit cell volumes (422,655 A(3) and 614,912 A(3), respectivel

39 lowing acute sterile inflammation, including cell volume (4364.4 +/- 489.6 vs. 1787.6 +/- 111.0 mum(3

40 Vesicle motility recovered long after cell volume, a process that required functional regulato

41 f DNA and the key division protein FtsZ with cell volume, a strong dependency of sensitivity to speci

42 Nevertheless, we know little of how cell volume affects neuronal dynamics.

43 terference RNA abolished the recovery of the cell volume after swelling induced by hypotonic challeng

44 ered shape involves differences in notochord cell volume along the anterior-posterior axis.

45 uced the plasticity of GBM cells in reducing cell volume, an effect that proved crucial in facilitati

46 les constitute approximately 2% of the total cell volume and are evenly spaced along the long cell ax

47 the surface area of the membrane relative to cell volume and can be modulated by changing membrane co

48 ifferentiation leads to a marked increase in cell volume and dilution of corneal crystallins associat

49 tropic growth and tight coordination between cell volume and DNA synthesis.

50 Cell volume and dry mass are typically correlated.

51 rtant cellular osmolyte in autoregulation of cell volume and fluid balance, particularly for mammalia

52 ost reliable for demonstrating increased red cell volume and for monitoring response to therapy; also

53 tion-chloride cotransporters (CCC), regulate cell volume and gamma-aminobutyric acid (GABA)-ergic neu

54 characterized by a simultaneous decrease in cell volume and increase in cell density, which occurs b

55 te cells and is crucial in the regulation of cell volume and intracellular chloride concentration.

56 the negative feedback loop that interrelates cell volume and its content of potassium ions.

57 Cell volume and its regulation are key factors for cellu

58 f superlattice structures both expanded unit-cell volume and large octahedral rotations are experimen

59 Additionally, cell volume and light absorption properties increased in

60 Changes in extracellular osmolarity affect cell volume and may impact various cellular processes su

61 ted sodium channels are temporarily blocked, cell volume and membrane potential normalize, yielding a

62 system for maintaining homeostatic values of cell volume and membrane tension could explain cell tens

63 we find that intraspecific distributions of cell volume and metabolic rates collapse onto a universa

64 int measurements at the single-cell level of cell volume and nitrogen/carbon uptake rates, as proxies

65 to that of DPN, with increased pigmentation, cell volume and nuclear cyclin D1 levels.

66 Once individual measurements of cell volume and nutrient uptake rate within a species ar

67 The desired combination of large unit-cell volume and octahedral rotations is normally contrai

68 impact of structural parameters (i.e., unit-cell volume and octahedral rotations) on ionic conductiv

69 d that such asymmetry in the partitioning of cell volume and of aging-associated damage confers a fit

70 ia control potassium homeostasis to maintain cell volume and osmotic potential.

71 From unit-cell volume and phase equilibrium considerations, we inf

72 g invasion represent the smallest achievable cell volume and require glioma cells to release all free

73 most cell functions including the control of cell volume and resting membrane potential.

74 stress, membrane fracturing, and changes in cell volume and shape leading to an overcrowded cytoplas

75 lly, must coordinate their growth, division, cell volume and shape with the inheritance of the genome

76 ovement and gravity, and to sense changes in cell volume and shape.

77 me and label-free observations of changes in cell volume and shape.

78 , intestine length, intestine weight, packed cell volume and spleen weight.

79 sional mobility is induced by a reduction in cell volume and subsequent increase in molecular crowdin

80 n these drastic shape changes occur rapidly, cell volume and surface area are approximately conserved

81 We propose that reductions in cell volume and the amounts of limiting components, such

82 functionally cooperate and regulate mitotic cell volume and tumor progression.

83 lutes that drive reversible changes in guard cell volume and turgor.

84 more than a century, of how plants regulate cell volume and turgor.

85 tochondria were larger, occupied more of the cell volume and were more densely clustered.

86 Calculations reveal that larger unit-cell volumes and octahedral rotations decrease migration

87 observation that crystals with reduced unit-cell volumes and tighter macromolecular packing often pr

88 esults and a novel stochastic model tracking cell-volume and cell-cycle predicts the experimental res

89 vel, reticulocyte hemoglobin level, and mean cell volume) and parental assessment of neurodevelopment

90 ed by the number of unattached kinetochores, cell volume, and cell fate.

91 is robust to changes of tissue surface area, cell volume, and cell number, which we confirm in vivo.

92 ecreased mean corpuscular hemoglobinand mean cell volume, and had no observable impact on mean corpus

93 ystem that quantifies the oxygen saturation, cell volume, and Hb concentration for individual RBCs in

94 ith experimental data on lactate production, cell volume, and O2 consumption revealed that glycolysis

95 significantly higher, while hematocrit, mean cell volume, and platelet counts were significantly lowe

96 yses showed lower total cell number, smaller cell volume, and reduced level of endoreduplication in t

97 he distribution of nutrient uptake rates and cell volume are found to hold across 3 orders of magnitu

98 a mathematical formulation of foraminiferal cell volume as a predictor of respiration and denitrific

99 parameters reflected a decrease in the unit cell volume as a result of the partial substitution of C

100 space of up to approximately 24% of the unit-cell volume as highly positive-charged organic templates

101 the lattice parameter axial ratios, the unit cell volume, as well as in specific interatomic bond len

102 l Polarity (PCP) pathway-independent sibling cell volume asymmetries that precede notochord cell inte

103 Here, we quantify sibling cell volume asymmetry throughout the developing notochor

104 In response to increases in cell volume, BECs release ATP, which was dependent on in

105 ria remain JAK2 positivity and increased red cell volume, but Cr-51 RCM is mandatory for patients who

106 th of the microalga, up to six-fold, and its cell volume by about three-fold.

107 coordinate electrical signalling and control cell volume by gating in response to membrane depolariza

108 We control cell volume by modulating media osmotic pressure and obs

109 VRACs) play an important role in controlling cell volume by opening upon cell swelling.

110 In eukaryotic cells, small changes in cell volume can serve as important signals for cell prol

111 Furthermore, the distributions of local cell volumes can be collapsed onto a universal curve usi

112 Here, general formulations concerning cell volume change are presented in the context of devel

113 is first-order and is accompanied by a unit cell volume change of about 10%.

114 Cell volume changes are ubiquitous in normal and patholo

115 Further, we find an upper limit of 0.02% for cell volume changes during an action potential.

116 Detailed "sub-models" describe cell volume changes during proliferation and necrosis; w

117 The extent, mechanism, and function of cell volume changes during specific cellular events, suc

118 stems to visualize and quantitatively assess cell volume changes of human glioma cells invading withi

119 (2020) show that cell volume changes upon osmotic stress result in rapid

120 nsition under compression with ca. 22 % unit-cell volume changes, which was found to be coupled with

121 Rapid changes in cell volume characterize macrophage activation, but the

122 in regulating trans-epithelial ion movement, cell volume, chloride homeostasis and neuronal excitabil

123 aration (HOPS) correlates with the degree of cell volume compression, distinct from SG assembly, and

124 rogels, these results reveal cell sensing of cell volume confinement as an adhesion-independent mecha

125 The cell volume continuously changes in response to varying

126 r changes in the AKT pathway, this defective cell volume control is specifically associated with hype

127 cytoskeletal dynamics, mTor regulation, and cell volume control.

128 They have critical roles in regulating cell volume, controlling ion absorption and secretion ac

129 36.2 +/- 2.58 and 31.5 +/- 4.66 mumol L(-1) cell volume (CV) h(-1) in comparison with the +CO2 treat

130 in vivo, manifesting as a loss of regulatory cell volume decrease following osmotic swelling.

131 uces endogenous VRAC currents and regulatory cell volume decrease in various cell types.

132 l response to dehydration measured: the unit cell volumes decrease by 9.8%, 7.7%, and 7.1% for Na-, K

133 enopus laevis embryogenesis both nuclear and cell volumes decrease with the nuclear-to-cytoplasmic (N

134 During spreading, the cell volume decreases by several thousand cubic micromet

135 Although the unit cell volume decreases over 27%, the quality of the singl

136 thway and the BK(Ca)-channel in mediating SC cell volume decreases.

137 els indicates a constant ratio of nucleus-to-cell volume, despite MSCs' lineage plasticity.

138 otic bodies and can be used on samples where cell volume determination alone would be difficult or in

139 romoting MB tumor progression via regulating cell volume dynamics, the perturbation of which activate

140 medulloblastoma (MB) cells to regulate local cell volume dynamics, thereby facilitating cell motility

141 oid appears to influence division both via a cell volume effect and by nucleoid occlusion, even in th

142 the nonmonotonic variation of band gap, unit cell volume, electrical conductivity, and Seebeck coeffi

143 Furthermore, the increase in maximal cell volume elicited by hypoosmotic stimulation was sign

144 instead, extracellular matrix deposition and cell volume enlargement are the key contributors to embr

145 the pressure-dependent decrease of the unit cell volume exhibits a slope change when entering phase

146 In slower relaxing gels, restriction of cell volume expansion by elastic stresses led to increas

147 of CaBaZn(2)Ga(2)O(7) leads to an unexpected cell volume expansion of CaBa(1-x)Pb(x)Zn(2)Ga(2)O(7) (0

148 The unprecedented cell volume expansion of the CaBa(1-x)Pb(x)Zn(2)Ga(2)O(7

149 on accumulates at a rate proportional to the cell volume growth and is modulated by the clock.

150 Measurements of red cell volume, hemoglobin (Hb) concentration and Hb conten

151 ration ([Cl(-)]i) regulation impacts on both cell volume homeostasis and Cl(-)-permeable GABAA recept

152 Cell volume homeostasis is vital for the maintenance of

153 Cell volume homeostasis requires the dynamically regulat

154 reby modulate a range of processes including cell volume homeostasis, blood pressure, hearing, and ki

155 orted morphological observations on the beta-cell volume, implying that [(11)C]5-HTP retention is a u

156 to the difficulty in accurately quantifying cell volume in a high-throughput manner.

157 sion and release in response to increases in cell volume in a protein kinase C-dependent manner.

158 t number per cell varied proportionally with cell volume in all three clones, indicating concentratio

159 he DNA, RNA, and protein levels decline with cell volume in both bacteria and eukaryotes.

160 sults suggest that YAP/TAZ may be modulating cell volume in combination with cytoskeletal tension dur

161 As mitochondria occupy up to 40% of the cell volume in highly metabolically active heart and fli

162 ng," of mRNA and protein quantities with the cell volume in order to maintain biomolecule concentrati

163 glutamate, ion concentrations, and dynamics cell volume in other brain pathologies and normal brain

164 This work demonstrates the role of cell volume in regulating cell fate in 3D culture, and i

165 Maintenance of a constant cell volume in response to extracellular or intracellula

166 , and it plays a central role in maintaining cell volume in response to osmotic challenges.

167 the MCS volume, linked to a reduction of the cell volume in the core of the MCS.

168 rs, and functions as a molecular rheostat of cell volume in the mammalian brain.

169 dose-dependent manner and reduced prostatic cell volume in vitro.

170 arly demyelination with loss of cells and/or cell volumes in cortical and white matter lesions, with

171 We found pyramidal cell volumes in layers III and V in the dorsolateral pre

172 aging of up to 15-mum-thick whole eukaryotic cell volumes in three to five imaging planes.

173 section images, allowing us to acquire whole cell volumes in which to scan for centrosomes.

174 Biphalin also significantly decreased the cell volume increase in primary neuronal cells exposed t

175 sis of pancreas indicated a significant beta-cell volume increase in transplanted rats, compared with

176 and protein biosynthesis in accordance with cell volume increase, which effectively leads to cytopla

177 ition from telophase to cytokinesis, whereas cell volume increased slightly in metaphase and was rela

178 brevetoxin production remained low, average cell volume increased.

179 RPV4 channels as transducers of mouse Muller cell volume increases into physiological responses.

180 uch as electrical plasma membrane potential, cell volume, intracellular [Ca(2+)] and pH, endocytosed

181 solateral domain of epithelia that regulates cell volume, ion transport, and acid-base balance; mice

182 ed paradigm, TRPV4 is activated by increased cell volume irrespective of the molecular mechanism unde

183 The maintenance of precise cell volume is critical for cell survival.

184 Dilution caused by increasing cell volume is included.

185 Regulation of cell volume is of great importance because persistent sw

186 Cell volume is restored rapidly by ion influx but at the

187 ioning of damaged cellular components and of cell volume, is a cell biological phenomenon experienced

188 model whereby TRPV4 differentially regulates cell volume, lipid, and calcium signals in NPE and PE ce

189 Moreover, cell volume lost apically due to constriction largely ba

190 ed resulting in larger band gap, larger unit cell volume, lower trap-state density, and much longer c

191 that cellular uptake is proportional to the cell volume (mass) or surface area and hence follow a cu

192 Cell volume may be altered either by variations in the e

193 This raises the possibility that cell volume may be the reason the SAC is weak, and chrom

194 d using only three red cell parameters: mean cell volume (MCV), red cell distribution width (RDW) and

195 henotypic shift was observed with histology, cell volume measurement, and MTT assay.

196 ed single-molecule mRNA counting with single-cell volume measurements to quantify the statistics of b

197 The cell volume, mechanical properties, and actin cytoskelet

198 undamental physiological parameters, such as cell volume, membrane potential, and intracellular pH.

199 adient plays an important role in regulating cell volume, membrane potential, pH, secretion, and the

200 of cell membrane potential, ion homeostasis, cell volume, mitochondrial ATP production, mitochondrial

201 In normal erythrocytes, it is involved in cell volume modification.

202 Under these conditions, the cell volume must be regulated to maintain optimal neural

203 ated with a reduction in both Hb content and cell volume: normal cells are likely to be removed by th

204 Inaccuracy in the estimation of cell volume (nuo) is the major source of error in the ca

205 volume, starch content, and amount of starch/cell volume obey lognormal distributions.

206 f zeolite ZSM-25, which has the largest unit-cell volume of all known zeolites (91,554 cubic angstrom

207 microfluidic injection system resulting in a cell volume of approximately 50 muL.

208 f GRP antagonist RC-3940-II on viability and cell volume of BPH-1 human prostate epithelial cells and

209 The cell volume of calcein AM-loaded keratocytes and myofibr

210 Furthermore, we observe an increasing mean cell volume of the Peruvian foraminifera, under higher N

211 2), a complex material with a primitive unit cell volume of ~6858 A(3) and ~285 atoms per primitive u

212 remained stably restrained with up to eight cell volumes of liquid passing through the acoustofluidi

213 Adipocyte cell volume on histology was 25-fold higher in 14- to 16

214 d the first detailed study of the effects of cell volume on neuronal dynamics.

215 Necrosis is depicted by a gain in cell volume (oncosis), swelling of organelles, plasma me

216 le- and multicell level, finding that single-cell volumes oscillate with a timescale of 4 h and an am

217 cells genetically manipulated to decrease in cell volume, PCH-2 is no longer required for the spindle

218 The cell volume permissible for a specified degree of loss o

219 He had a normal haemoglobin, mean cell volume, platelet and clotting function.

220 acute and persistent increase in hepatocyte cell volume, proliferation, and transcription of genes t

221 olume-to-surface ratio (r=0.78, P<0.001) and cell volume (r=0.75, P<0.001).

222 f Na(+)/K(+)-ATPase functioning, where below cell volume rapidly increases as a function of the remai

223 of the energy supply exists, below which the cell volume rapidly increases.

224 lls with bilobed nuclei had the same nuclear:cell volume ratio as cells with round nuclei.

225 The calibration accounts for matrix:cell volume ratio, high- and low-affinity binding, activ

226 the result of hemodilution or true red blood cell volume (RBCV) deficit.

227 After the post-ET assessment, red blood cell volume (RBCV) was re-established at the pre-ET leve

228 We show that cell volume reaches the same maximal level irrespective

229 on led to persistent blebbing and attenuated cell volume recovery.

230 on of EAG2 in cells at interphase results in cell volume reduction and mitotic-like morphology.

231 membrane impermeable solute results in total cell volume reduction with no plasmolysis, whereas a sho

232 y a factor of 100, despite a contracted unit cell volume reflecting a positive chemical pressure effe

233 lated anion channels (VRACs) are crucial for cell volume regulation and have many other important rol

234 tation embryos first in a novel mechanism of cell volume regulation and second as a major methyl dono

235 mammalian brain, with implications for both cell volume regulation and/or GABAergic signaling.

236 Collectively, our data identify cell volume regulation as a basic conserved homeostatic

237 udy, we evaluated the effects of normalizing cell volume regulation by adding glycine, an organic osm

238 cell swelling and critically contributes to cell volume regulation in astrocytes.

239 Octanoate significantly attenuated cell volume regulation in hypotonic solutions, consisten

240 Cell volume regulation is a primitive response to altera

241 semble of ion transport proteins involved in cell volume regulation is well established, the molecula

242 Its contribution to cell volume regulation might include interactions with a

243 Cell volume regulation was measured using a video-imagin

244 Impaired cell volume regulation will likely contribute to altered

245 In eukaryotes, they are implicated in cell volume regulation, acidification, and cell cycle.

246 is translocation, which has a direct role in cell volume regulation, occurs within 30 s and is depend

247 across the plasma membrane and are vital for cell volume regulation, salt reabsorption in the kidney,

248 across channels that have a relevant role in cell volume regulation.

249 ions including endocytosis, drug efflux, and cell volume regulation.

250 ulated anion channels (VRACs) are central to cell volume regulation.

251 ell migration in confinement that depends on cell-volume regulation via water permeation.

252 l changes due to cytoskeletal modulation and cell-volume regulation.

253 ked increased biochemical association of the cell volume regulator Src with MLCK and with the endocyt

254 y 10 to 160 pg of brevetoxin per cell, while cell volume remained stable.

255 Volume changes deviating from original cell volume represent a major challenge for cellular hom

256 f each model and the significant decrease in cell volume resulting from administration of the cytotox

257 parameter ratio with minimal change in unit cell volume, reveals the existence of a three-stage cati

258 e relationship between transcript number and cell volume sets the biological stochasticity of living

259 d temperature worsened the ATP depletion and cell volume shrinkage.

260 r related cubic structure of comparable unit cell volume (space group Pa3, a = 22.4310(15) A, V = 112

261 ncentrations with cell phospholipid content, cell volume, sphericity, and other cell phenotypic featu

262 nto the sink provided by the large granulosa cell volume, such that by 20 min the cGMP concentration

263 dr2Delta mutant is more closely specified by cell volume, suggesting that Cdr2 is essential for area

264 entry into S phase at inappropriately small cell volumes, suggesting that JAG can override a cell si

265 sed on an increased ratio of surface area to cell volume synthesis [6, 7].

266 Patients with ATTR had a higher total cell volume than did healthy subjects (mean, 53 mL/m(2)

267 ns in sodium intracellular concentration and cell volume that must be maintained within narrow ranges

268 erned by osmotically driven changes in guard cell volume, the role of membrane water channels (aquapo

269 of pre-existing ribosomes and a reduction in cell volume, thereby maintaining the density of ribosome

270 contractility and (2) through regulation of cell volume through ion transport.

271 transcription rate increases in parallel to cell volume to compensate it by keeping the actual mRNA

272 ty on the reduced volume (i.e., the ratio of cell volume to its maximal possible volume) of RBC disco

273 Here, we use rapid perturbation of cell volume to modulate the concentration of weakly boun

274 etic method, we show that small increases in cell volume to reduce the hemoglobin concentration can r

275 We used rapid imaging of the full cell volume to uncover the dynamic steps that underlie t

276 hanges in ion concentrations, glutamate, and cell volume together with exchange of matter between cel

277 tion of nanomaterial suspensions in a packed cell volume tube, and is validated against gold-standard

278 Mean ASM cell volume (V(C)), the number of ASM cells per length o

279 ation (15.2%, 5.8%, and 19.0% for half-time, cell volume [V(o)], and hydraulic conductivity [L(p)], r

280 larger, due to a significant contribution of cell volume variability.

281 dinal, and parallel increase in histological cell volume, volume-to-surface ratio, and tauic between

282 Cell volume was monitored by electronic cell sorting.

283 1; P = .001), but in patients with AL, total cell volume was normal (mean, 47 mL/m(2) +/- 17 vs 45 mL

284 ive oxygen species generation or a change in cell volume was not necessary for NLRP3 activation.

285 Using an independent measurement of cell volume, we find cell density to be approximately 1.

286 of the regenerated myocyte mass and myocyte cell volume were greater in animals injected with hCSCs

287 ECV and total cell volume were measured in the heart.

288 uniqueness of steady-state solutions of the cell volume were validated, and contributions of individ

289 Histological cardiomyocyte diameters and cell volumes were higher in mice treated with L-NAME com

290 water efflux and a concomitant reduction in cell volume, which is countered by the accumulation of o

291 AL; however, ATTR is associated with higher cell volume, which suggests concomitant cell hypertrophy

292 n state, compressive strain reduces the unit-cell volume while maintaining large octahedral rotations

293 ity, while tensile strain increases the unit-cell volume while quenching octahedral rotations, result

294 ions can be made for the maximum permissible cell volume with a packed column for a given column effi

295 mutant that has undergone a 70% reduction in cell volume with respect to wild type.

296 growth, and decoupling of DNA synthesis from cell volume, with a concomitant increase in cell size he

297 iately rescaled by a function of the average cell volume within each species, we find that intraspeci

298 junctions can amplify spatial variations in cell volume within multicellular spheroids and, further,

299 relationships between Whi5 concentration and cell volume without diminishing size control in the G1 p

300 This allows the recovery of the cell volume without increasing intracellular ionic stren