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1 Rejections after conversion were mostly cell-mediated.
2 ations to the myofiber through a muscle stem cell-mediated accumulation of total myonuclei and a conc
8 ced both a complete antitumor response and T cell-mediated allograft rejection requiring reinitiation
9 t the deregulation of pathways involved in T cell-mediated allorecognition is a distinctive feature a
11 determine whether Tregs suppress effector T cell-mediated and inflammatory cytokine-induced CEnC dea
12 acity in protecting CEnCs against effector T cell-mediated and interferon-gamma and tumor necrosis fa
13 rformance of the kSORT assay to detect AR (T cell-mediated and/or antibody-mediated rejection) as com
14 tend to occur later, may be associated with cell-mediated and/or antibody-mediated rejection, and po
17 tly, therapeutic blockade of PD-1 enhances T cell-mediated anti-tumor immunity, but many patients do
20 gs define PTPN2 as a target for bolstering T-cell-mediated anti-tumour immunity and CAR T-cell therap
21 eckpoint blockade synergistically enhanced T cell-mediated anti-tumour immunity and induced ferroptos
22 y we investigated the interplay between MAIT cell-mediated antibacterial effector functions and the h
23 munoparalysis is defined by diminished CD8 T cell-mediated antitumor immunity that can respond to tim
24 " tumors to hot, generates systemic CD8(+) T cell-mediated antitumor immunity, and sensitizes resista
31 reduced neuropathology in the classic CD4+ T cell-mediated autoimmune disease experimental autoimmune
39 r therapeutic activity in a mouse model of T cell-mediated autoimmunity that mimics multiple sclerosi
42 nt bone marrow failure disorders linked to T-cell-mediated autoimmunity; they are associated with an
44 ffusion of the pollutant substrates into the cell, mediated by specialised outer membrane (OM) channe
45 f cases the translocation occurs in mature B cells mediated by activation-induced cytidine deaminase.
47 nslocation is mainly acquired in precursor B cells mediated by recombination-activating genes in both
49 ls and their subsequent delivery into cancer cells, mediated by transferrin receptors, in a complex b
50 eta (TGF-beta) suppresses T helper 2 (T(H)2)-cell-mediated cancer immunity(9), we show that blocking
51 checkpoint P2X7 may be targeted to enhance T-cell-mediated cancer immunotherapy and improve T effecto
54 genesis in a turbidity assay and upregulates cell-mediated collagen compaction and reorganization, wh
55 hich the antigens are intracellular (often T cell-mediated) compared with disorders in which the anti
59 tibility of surviving cancer cells to CD8+ T cell-mediated control through enhanced MHC-I expression.
61 ogramming nanoparticles led to a significant cell-mediated cytotoxic immune response with systemic ef
64 s (FcgammaRs) and mediate antibody-dependent cell-mediated cytotoxicity (ADCC) may play a dominant ro
65 bola viruses and elicited antibody-dependent cell-mediated cytotoxicity (ADCC) responses against EBOV
66 nctional capability of inducing Ab-dependent cell-mediated cytotoxicity (ADCC), complement deposition
67 reased ability to mediate antibody-dependent cell-mediated cytotoxicity (ADCC), during HCV infection
70 or functional activities (antibody-dependent cell-mediated cytotoxicity and antibody-dependent cell-m
71 ement, Increased IFN-gamma secretion, and NK cell-mediated cytotoxicity and higher percentages of CD8
75 and MICB genes related to antibody-dependent cell-mediated cytotoxicity were identified in tumors wit
76 ural killer (NK) cells by antibody-dependent cell-mediated cytotoxicity, both RIFIN and MHC are recru
77 e often associated with inherited defects in cell-mediated cytotoxicity, serves as a prototypical CSS
78 ed robust, cross-reactive antibody-dependent cell-mediated cytotoxicity-mediating and neuraminidase-i
83 gs are resistant to human humoral rejection, cell-mediated damage and pathogenesis associated with dy
85 that promotes fibrin degradation, thwarts T cell-mediated defense against fully virulent Y. pestis I
87 l autoimmune encephalomyelitis is a CD4(+) T cell-mediated demyelinating disease of the CNS that serv
88 D4(+) T cell response and augmented CD8(+) T cell-mediated destruction of the cancer cells in vitro a
89 paracrine-signalling events, such as tumour-cell-mediated differentiation of macrophages and macroph
90 sing rheumatoid arthritis as an example of T cell mediated disease, we demonstrate interactions of ex
91 ounting evidence that IBM is an autoimmune T cell-mediated disease provides hope that future therapie
92 autoimmune myocarditis (TnI-AM), a CD4(+) T-cell-mediated disease, was induced in mice lacking all 3
94 nhibition might have a therapeutic role in T cell-mediated diseases, including atopic dermatitis (AD)
97 ically contributes to the development of Th2 cell-mediated disorders, most likely by influencing IFNg
100 f light chain fibrils, a potential method of cell-mediated dissolution, amyloid-like fibrils were lab
105 nity for NKp30 and significantly improved NK cell-mediated, EGFR-dependent killing of tumor cells com
108 T cells, but not CD4 cells or natural killer cells, mediated elimination of KPC-Par-1(KO) tumor cells
109 h translated into sub-nanomolar gammadelta T-cell-mediated eradication of bladder cancer cells in vit
110 to directly test the survival value of the M cell-mediated escapes and to show that the absence of th
111 ingly unclear: An actual survival value of M cell-mediated escapes has never been supported experimen
112 on in VAT Treg cells, and consequential Treg-cell-mediated generation of 15-keto PGE(2) suppressed co
113 ys was the most prominent, suggesting that T cell-mediated graft rejection could be the cause of the
116 Interestingly, the FcgammaRIIIA(+) CD8 T cells mediated HIV-specific Ab-dependent cellular cytoto
117 novel role of B cells as regulators of CD8 T cell-mediated host resistance and memory CD8 T cell form
118 D-scidIL2Rgamma(null) (NSG) mouse model of T-cell-mediated human islet allograft rejection and develo
119 ed in type IV (also termed delayed-type or T cell-mediated) hypersensitivity reactions in response to
120 rly during development, durably influences T cell mediated immune responses across the lifespan.
121 Glycoprotein E (gE)-specific humoral and cell-mediated immune (CMI) responses and the correlation
125 function in ovariectomized mice and prevent cell-mediated immune rejection in immune competent mice.
126 e we investigate the impact of HOPE on the T cell-mediated immune response following kidney transplan
128 osal antibody profile, and a more consistent cell-mediated immune response profile compared with CTH5
130 ulted in modest, significant boosting of the cell-mediated immune response to Ag85A (p = 0.027; 95% C
134 -CoV-2-S induces robust systemic humoral and cell-mediated immune responses and protects against lung
135 an important endogenous function of MDR1 in cell-mediated immune responses and suggest that ongoing
136 ysical interactions; moreover, they induce T-cell-mediated immune responses critical to psoriasis.
138 ested a protective role for both humoral and cell-mediated immune responses in recovery from COVID-19
142 l responses can drive protective humoral and cell-mediated immune responses(2) and might reduce the p
144 ncer risk was observed for higher FOXP3(+) T-cell-mediated immune tolerance and lower CD8(+) T-cell-m
146 lue of monitoring pretransplant CMV-specific cell-mediated immunity (CMI) using an interferon-gamma r
149 infection, further confirming that CD4(+) T cell-mediated immunity against Brucella is inhibited by
151 tations, identify key molecules required for cell-mediated immunity against EBV, and develop immunoth
152 e essential for cross-presentation and CD8 T cell-mediated immunity against intracellular pathogens a
155 the ability of B cells to suppress CD4(+) T cell-mediated immunity and modulate CD4(+) T cell effect
160 ul experimental approach to directly study T-cell-mediated immunity in vivo In the rhesus macaque AID
166 nfection may modulate the establishment of T cell-mediated immunity, adversely affecting long-term pr
167 immune cross-protection, improve humoral and cell-mediated immunity, and promote antigen dose sparing
168 ta deletion does not impair overall CD8(+) T cell-mediated immunity, including antiviral immunity, im
169 that regulate the quality and magnitude of T cell-mediated immunity, known as tolerance checkpoints.
171 Adult frogs possess efficient conventional T cell-mediated immunity, whereas tadpoles predominantly r
186 s well as for designing vaccines that elicit cell-mediated immunity.IMPORTANCE The high morbidity and
187 SAEs), biochemical/hematological parameters, cell-mediated immunogenicity by enzyme-linked immunospot
188 udies have suggested an important role for T-cell-mediated immunopathology in LF pathogenesis, but th
190 receptor programmed cell death 1 promotes T-cell-mediated immunosurveillance against tumours, and ha
196 3 (and not CXCR3CXCR5) OVA-primed OT-I CD8 T cells mediated in vivo suppression of anti-OVA antibody
199 w, we focus on the characteristics of immune cell-mediated inflammation in islets and the consequence
200 iscovered IgGs heighten pain indirectly by T-cell-mediated inflammation or destruction of targets wit
201 ted bone resorption and attenuates dendritic cell-mediated inflammation through impairing acidificati
204 upporting remyelination by promoting myeloid cell-mediated inflammatory responses via TNF-alpha, whic
206 utes likely tune the extent of neurogliaform cell mediated inhibition thus constituting canonical cir
207 hestrated suppression of natural killer (NK) cell-mediated innate antitumor immunity, leading to incr
209 Here we show that STAT1 enables CD4(+) T-cell-mediated intestinal inflammation by protecting them
212 ntation, and in initiating specific CD8(+) T-cell-mediated killing of antigen-loaded target cells in
215 eatments, possessing the ability to elicit T cell-mediated killing of tumor cells and prevent disease
216 id tumors that are typically resistant to NK cell-mediated killing, demonstrating the feasibility of
217 ckdown sensitizes tumor cells to cytotoxic T cell-mediated killing, improving CAR T cell therapy.
223 rotection, that mainly correlated with low T cell mediated Leishmania-specific IL-4 and IL-10 respons
228 activity, and provision of help for CD8(+) T cell-mediated memory responses, limiting host defense an
230 Glp1r agonism was tested in a nondiabetic, T-cell-mediated murine model of nephrotoxic serum nephriti
231 In agreement with our in vitro data, mast cell-mediated passive cutaneous anaphylaxis and passive
233 which noncoding risk variants influence the cell-mediated pathogenesis of immune-mediated disease (I
234 (acetate, propionate, and butyrate) on mast cell-mediated pathology and human mast cell activation,
236 at each point in space, we find a horizontal-cell-mediated pathway similar to that found in mammals.
237 opulations which may have implications for T cell-mediated processes such as inflammation and immuno-
238 e, we investigated whether B cells inhibit T cell-mediated protection against Brucella Using B and T
241 dy depletion approach, we confirmed CD4(+) T cell-mediated protective immunity and a CD8(+) T cell-de
244 cipients had a relatively low incidence of T cell-mediated rejection (9.2%) and antibody-mediated rej
246 clinical importance of subclinical, early T cell-mediated rejection (Banff TCMR 1A and borderline le
247 ted the effect of clinical and subclinical T cell-mediated rejection (C-TCMR and SC-TCMR) on allograf
249 4 groups: normal "R1(normal) " (N = 129), T cell-mediated rejection (TCMR) "R2(TCMR) " (N = 37), ear
250 arteriolitis/vasculitis in the setting of T cell-mediated rejection (TCMR) and antibody-mediated rej
251 esponses in renal allografts with those in T-cell-mediated rejection (TCMR) and chronic antibody-medi
252 ts to the criteria for chronic active (CA) T cell-mediated rejection (TCMR), borderline, and antibody
256 ecular phenotype of both acute and chronic T cell-mediated rejection and antibody-mediated rejection
260 allograft specimens showed grade 2A acute T cell-mediated rejection, cortical infarction, or acute t
268 ells in regulating the balance between CD8 T cell-mediated resistance against respiratory viral infec
271 gp100 and WT1 tumor antigen induced a CD8+ T-cell-mediated response in tumor-transplanted syngeneic m
274 activation of T cells and no increase in Th2 cell-mediated responses compared with control mice.
275 fy Ptpn2 as a negative regulator of CD8(+) T cell-mediated responses to LCMV Clone 13 viral infection
277 ecular and cellular analyses of cells from T-cell-mediated RJ and nonrejected kidney transplant patie
278 llowing skin transplantation, the donor mast cell-mediated senescence in FRCs was associated with col
279 , as shown in vitro, and suggests that PV(+) cell-mediated short-term synaptic depression influences
280 RNA-seq and follow-up analyses showed cancer cell-mediated SIRT1 loss induced NF-kappaB signaling in
282 utrophils is required for autoreactive CD4 T cell-mediated skin disease pathogenesis and that the NLR
283 MHCII, represents a novel pathway for T(reg) cell-mediated suppression and may be a mechanism by whic
286 onses to interleukin (IL)-2 and regulatory T cell-mediated suppression, the composition of the B-cell
288 to 1) inhibit bone marrow-derived dendritic cell-mediated T cell functions and reduce serum anti-dsD
289 omponent of cytotoxic granules involved in T cell-mediated target cell-killing, and monomeric teal fl
290 Human leukocyte antigen (HLA)-independent, T cell-mediated targeting of cancer cells would allow immu
291 microenvironment stiffness leads to stromal cell-mediated TGF-beta family signaling relying on the i
292 BNZ-2 might be used to prevent cytotoxic T-cell-mediated tissue damage in complex immune disorders
293 that re-creates genetic susceptibility to T-cell-mediated tissue injury as observed in a mouse model
294 lls, ii) microscale materials can facilitate cell-mediated transport and serve as artificial antigen-
295 nd anti-PD-L1 synergistically improves CAR-T cell-mediated tumor control and survival, providing a st
297 tein 176B (TMEM176B) contributes to CD8(+) T cell-mediated tumor growth inhibition by unleashing infl
300 mediated cytotoxicity and antibody-dependent cell-mediated virus inhibition) were observed in serum o