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1 Avelumab (anti-PD-L1) induces NK cell-mediated cytotoxicity.
2 e the ability of myeloma cells to trigger NK cell-mediated cytotoxicity.
3 Arl8b), as a critical factor required for NK cell-mediated cytotoxicity.
4 nducing apoptosis through antibody-dependent cell-mediated cytotoxicity.
5 es RAE-1 expression and susceptibility to NK cell-mediated cytotoxicity.
6 ensed NK cells to mediate antibody-dependent cell-mediated cytotoxicity.
7 /HER3 enhanced the NKG2D-MICA/B-dependent NK cell-mediated cytotoxicity.
8 K cell activation through antibody-dependent cell-mediated cytotoxicity.
9 that lacks functionality for complement- and cell-mediated cytotoxicity.
10 ross-linked with antibodies it suppressed NK cell-mediated cytotoxicity.
11 hanced T-cell infiltration into tumors and T-cell-mediated cytotoxicity.
12 -RasV12 increased sensitivity of cells to NK cell-mediated cytotoxicity.
13 sera, reducing to near zero complement- and cell-mediated cytotoxicity.
14 ack NK cells and showed severely impaired NK cell-mediated cytotoxicity.
15 he exocytic events required for effective NK cell-mediated cytotoxicity.
16 attenuated Necl-5 binding and natural killer cell-mediated cytotoxicity.
17 nces rituximab-mediated, antibody-dependent, cell-mediated cytotoxicity.
18 ulation of these secretory events leading to cell-mediated cytotoxicity.
19 cells in vitro and caused their Ab-dependent cell-mediated cytotoxicity.
20 ptors, is implicated in the activation of NK cell-mediated cytotoxicity.
21 a 100-fold improvement in antibody-dependent cell-mediated cytotoxicity.
22 ituximab binding, and rituximab-dependent NK cell-mediated cytotoxicity.
23 d function of T regulatory cells may enhance cell-mediated cytotoxicity.
24 o bind FcgammaRIIIA and trigger Ab-dependent cell-mediated cytotoxicity.
25 nd defects in T-regulatory cells may enhance cell-mediated cytotoxicity.
26 L/TRAIL), three key mediators of immunologic cell-mediated cytotoxicity.
27 s downstream of CRACC/EAT-2 implicated in NK cell-mediated cytotoxicity.
28 -opsonized particles, and antibody-dependent cell-mediated cytotoxicity.
29 d decreases susceptibility to natural killer cell-mediated cytotoxicity.
30 lls with poly(I:C) significantly augments NK cell-mediated cytotoxicity.
31 scFv-Fc did not enhance antibody-dependent cell-mediated cytotoxicity.
32 ling of apoptosis, complement activation and cell-mediated cytotoxicity.
33 e xenograft rejection and antibody-dependent cell-mediated cytotoxicity.
34 mplement-dependent and/or antibody-dependent cell-mediated cytotoxicity.
35 by a reduction in susceptibility to human NK cell-mediated cytotoxicity.
36 tumor cell resistance to natural killer (NK) cell-mediated cytotoxicity.
37 production, phagocytosis, and Ab-dependent, cell-mediated cytotoxicity.
38 t rejection, interferon-gamma production and cell-mediated cytotoxicity.
39 ally modified cells resist Ab-independent NK cell-mediated cytotoxicity.
40 d to play a role in tumor cell resistance to cell-mediated cytotoxicity.
41 susceptibility of porcine cells to human NK cell-mediated cytotoxicity.
42 protect xenogeneic endothelial cells from NK cell-mediated cytotoxicity.
43 re either protected or are susceptible to NK cell-mediated cytotoxicity.
44 lipid rafts and the subsequent generation of cell-mediated cytotoxicity.
45 le of death receptor-induced apoptosis in NK cell-mediated cytotoxicity.
46 ar IFN-gamma synthesis and markedly enhanced cell-mediated cytotoxicity.
47 be a positive regulatory role for 3BP2 in NK cell-mediated cytotoxicity.
48 P-1-mediated gene transcription and enhances cell-mediated cytotoxicity.
49 ators of opsonophagocytosis and Ab-dependent cell-mediated cytotoxicity.
50 ion critically influences the development of cell-mediated cytotoxicity.
51 1 resensitizes the K5-expressing cells to NK cell-mediated cytotoxicity.
52 uence, K5 expression drastically inhibits NK cell-mediated cytotoxicity.
53 They have no effect on NK cell-mediated cytotoxicity.
54 terferon-gamma production and enhancement of cell-mediated cytotoxicity.
55 in vitro and caused their antibody-dependent cell-mediated cytotoxicity.
56 assessed the roles of p38 and JNK MAPK in NK cell-mediated cytotoxicity.
57 complement-mediated, and antibody-dependent cell-mediated cytotoxicity.
58 aptor protein for the regulation of human NK cell-mediated cytotoxicity.
59 omplement as well as to mediate Ab-dependent cell-mediated cytotoxicity.
60 eptibility of CMV-infected fibroblasts to NK cell-mediated cytotoxicity.
61 omplex (MHC) class I peptides and inhibit NK-cell-mediated cytotoxicity.
62 mediated immune tolerance and lower CD8(+) T-cell-mediated cytotoxicity.
63 BB signaling can increase antibody-dependent cell-mediated cytotoxicity.
64 chanisms likely involving antibody-dependent cell-mediated cytotoxicity.
65 ell activation, proliferation, and bystander cell-mediated cytotoxicity.
66 S response also directly suppressed CD8(+) T-cell-mediated cytotoxicity.
67 ucers and did not inhibit antibody-dependent cell-mediated cytotoxicity.
68 LRG1 expression; proliferation; and CD4(+) T cell-mediated cytotoxicity.
69 esumably NK cell-resistant tumor cells to NK cell-mediated cytotoxicity.
70 al forms, potent in vitro antibody-dependent cell-mediated cytotoxicity (0.1-0.3 mug/ml EC50), and hi
71 vitro, XmAb5574 enhanced antibody-dependent cell-mediated cytotoxicity 100-fold to 1,000-fold relati
73 of cellular mechanisms such as Ab-dependent cell-mediated cytotoxicity, Ab-dependent cellular phagoc
74 not males were correlated with Ab-dependent cell-mediated cytotoxicity activity against gp120 target
75 n the cotton rat and that antibody-dependent cell-mediated cytotoxicity activity can significantly en
76 cell assay, and moderate antibody-dependent, cell-mediated cytotoxicity activity was demonstrated.
82 d a means to modulate the antibody-dependent cell-mediated cytotoxicity (ADCC) activity of a humanize
83 g and function, including antibody-dependent cell-mediated cytotoxicity (ADCC) activity, at levels si
84 affinity by BIACORE, for antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-mediate
85 valuated functionally by antibody-dependent, cell-mediated cytotoxicity (ADCC) and for neutralization
86 the relationship between antibody-dependent cell-mediated cytotoxicity (ADCC) and virus neutralizati
87 f virus-infected cells by antibody-dependent cell-mediated cytotoxicity (ADCC) are limited by the num
88 ency virus (HIV)-specific antibody-dependent cell-mediated cytotoxicity (ADCC) are present in the cer
89 ulticolor flow cytometry, antibody-dependent cell-mediated cytotoxicity (ADCC) assay, and immunohisto
90 transfer experiments and antibody-dependent cell-mediated cytotoxicity (ADCC) assays indicate that t
92 umor cell killing such as antibody-dependent cell-mediated cytotoxicity (ADCC) by isolated monocytes,
96 or cell susceptibility to antibody-dependent cell-mediated cytotoxicity (ADCC) by selective desialyla
97 for cancer treatment via antibody-dependent cell-mediated cytotoxicity (ADCC) has been little studie
98 ouse bone marrow produced antibody-dependent cell-mediated cytotoxicity (ADCC) in cell cultures expre
99 immune serum, suggesting antibody-dependent cell-mediated cytotoxicity (ADCC) in F. novicida Deltafo
100 influence the outcome of antibody-dependent cell-mediated cytotoxicity (ADCC) in vitro and in animal
103 ecent studies demonstrate antibody-dependent cell-mediated cytotoxicity (ADCC) is one of the modes of
104 humoral immune response, antibody-dependent cell-mediated cytotoxicity (ADCC) may be a functioning m
105 s (FcgammaRs) and mediate antibody-dependent cell-mediated cytotoxicity (ADCC) may play a dominant ro
106 how they achieve a higher antibody-dependent cell-mediated cytotoxicity (ADCC) potency than native im
107 uated the kinetics of the antibody-dependent cell-mediated cytotoxicity (ADCC) response during acute
108 bola viruses and elicited antibody-dependent cell-mediated cytotoxicity (ADCC) responses against EBOV
110 ER3, and mediate enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) via glycoengineering o
111 complement-mediated killing and Ab-dependent cell-mediated cytotoxicity (ADCC) were compared between
112 ntaneous cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC) when triggered by ritu
113 of HIV-infected cells to antibody-dependent cell-mediated cytotoxicity (ADCC), and conversely that R
114 nctional capability of inducing Ab-dependent cell-mediated cytotoxicity (ADCC), complement deposition
115 ully understood, although antibody-dependent cell-mediated cytotoxicity (ADCC), complement-dependent
116 reased ability to mediate antibody-dependent cell-mediated cytotoxicity (ADCC), during HCV infection
117 of antibodies, including antibody-dependent cell-mediated cytotoxicity (ADCC), in prevention of huma
118 f virus-infected cells by antibody-dependent cell-mediated cytotoxicity (ADCC), we show that substitu
120 ed CML LSPCs by selective antibody-dependent cell-mediated cytotoxicity (ADCC)-facilitated lysis of C
144 as been shown to be sufficient to trigger NK cell-mediated cytotoxicity against Fc receptor-bearing c
145 n-like transcript 1 (LLT1) interaction in NK cell-mediated cytotoxicity against normal human articula
146 rmore, XmAb5574 conferred antibody-dependent cell-mediated cytotoxicity against patient-derived acute
147 ggest methods utilizing HLA-G to overcome NK cell-mediated cytotoxicity against porcine endothelial c
148 CD8+ T cell-mediated and natural killer (NK) cell-mediated cytotoxicity against renal tubular epithel
149 e of GJs in NK cell activation by DCs and NK cell-mediated cytotoxicity against tumor cells remains u
150 in NK cells leads to increased Ab-dependent cell-mediated cytotoxicity and "natural cytotoxicity," t
151 ity to lyse human tumor cells by both direct cell-mediated cytotoxicity and Ab-dependent cellular cyt
152 or functional activities (antibody-dependent cell-mediated cytotoxicity and antibody-dependent cell-m
153 rat Crry expressed on tumor cells has on rat cell-mediated cytotoxicity and antibody-dependent cell-m
154 activation of NK cells, thereby enhancing NK cell-mediated cytotoxicity and antibody-dependent cellul
155 we examined the potential contribution of T-cell-mediated cytotoxicity and apoptosis to mucosal clea
158 ally capable of recruiting host Ab-dependent cell-mediated cytotoxicity and complement-dependent cyto
159 render the Fc unable to direct Ab-dependent cell-mediated cytotoxicity and complement-dependent cyto
160 fector functions, such as antibody-dependent cell-mediated cytotoxicity and complement-dependent cyto
161 in the IgG format induced antibody-dependent cell-mediated cytotoxicity and complement-dependent-cyto
162 NK cells and LLT1 on target cells inhibit NK cell-mediated cytotoxicity and cytokine production and c
163 n, the mechanism by which DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production was e
164 vation of NF-kappaB that lead to impaired NK cell-mediated cytotoxicity and cytokine production.
165 by in vitro assays measuring KIR3DS1-induced cell-mediated cytotoxicity and cytokine production.
166 function, we assessed the role of ICOS in NK cell-mediated cytotoxicity and cytokine production.
167 N-glycans and had better antibody-dependent cell-mediated cytotoxicity and effector cell receptor bi
168 antibodies weakly induced antibody-dependent cell-mediated cytotoxicity and enhanced induction in the
169 es not greatly influence NK-cell or CD8(+) T-cell-mediated cytotoxicity and has minimal impact on cyt
170 ement, Increased IFN-gamma secretion, and NK cell-mediated cytotoxicity and higher percentages of CD8
172 G2D receptors, and decreases NKG2D-dependent cell-mediated cytotoxicity and IFN-gamma production.
173 dase inhibition, in vitro antibody-dependent cell-mediated cytotoxicity and in vivo protection agains
174 on, generalized but reversible defects in NK cell-mediated cytotoxicity and mild CD8(+) T cell defect
176 ctor function of CD8 T cells is mediated via cell-mediated cytotoxicity and production of cytokines l
177 adelta T lymphocytes in the regulation of NK cell-mediated cytotoxicity and provide rationale for the
178 fector cells of the immune system to enhance cell-mediated cytotoxicity and suggest investigation int
179 kinase to DAP10 could not by itself trigger cell-mediated cytotoxicity and that binding of an interm
181 th sequence homology for myosin, elicit both cell-mediated cytotoxicity and tumor necrosis factor-alp
182 suggest the importance of antibody-dependent cell-mediated cytotoxicity and/or apoptosis induction vi
183 ented anti-mouse mixed lymphocyte responses, cell-mediated cytotoxicity, and antibody production.
184 t-dependent cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and antibody-dependent cellu
185 as been shown to downregulate proliferation, cell-mediated cytotoxicity, and IFN-gamma production, as
186 ects in counter-regulatory functions enhance cell-mediated cytotoxicity, and interventions that promi
187 noglobulin G1 binding and antibody-dependent cell-mediated cytotoxicity, and may therefore influence
188 to FcgammaRIIIa, enhanced antibody-dependent cell-mediated cytotoxicity, and more than doubled the me
189 ects in counter-regulatory functions enhance cell-mediated cytotoxicity, and pharmacological interven
190 related to T-cell activation, natural killer cell-mediated cytotoxicity, and programmed cell death.
191 intracellular signaling, antibody-dependent cell-mediated cytotoxicity, and rapid target internaliza
192 N-alpha and -beta) are potent inducers of NK cell-mediated cytotoxicity, and that NK cells are import
193 es in human T cell activation/proliferation, cell-mediated cytotoxicity, and volume regulation and is
194 CD4(+) T-cell-mediated apoptosis or CD8(+) T-cell-mediated cytotoxicity as being critical to the clea
195 endent mechanisms leaves Fas/FasL-dependent, cell-mediated cytotoxicity as the major pathway for CTL-
198 Despite this, reverse antibody-dependent cell-mediated cytotoxicity assays showed potent degranul
199 ural killer (NK) cells by antibody-dependent cell-mediated cytotoxicity, both RIFIN and MHC are recru
200 hways not only are the major mechanisms of T cell-mediated cytotoxicity but also are involved in home
202 0 in lipid rafts, affects antibody-dependent cell-mediated cytotoxicity, but not complement-dependent
203 There was dose-dependent inhibition of LAK cell-mediated cytotoxicity, but this effect was not seen
204 ic unresponsiveness developed as assessed by cell-mediated cytotoxicity by blood mononuclear cells in
205 -22 decreased epithelial susceptibility to T cell-mediated cytotoxicity by inhibiting the IFN-gamma-i
207 negative Rac1 inhibits the development of NK cell-mediated cytotoxicity by two mechanisms: (a) conjug
209 cells that are comparatively resistant to NK cell-mediated cytotoxicity caused by the paucity of othe
210 therapeutic antibodies, complement-dependent cell-mediated cytotoxicity (CDCC) and complement-depende
212 esting IgM functions by complement-dependent cell-mediated cytotoxicity (CDCC), a mechanism thought t
213 ion, resulting in greater antibody-dependent cell-mediated cytotoxicity compared with IL-21 and/or an
214 re for the enhancement of antibody-dependent cell-mediated cytotoxicity, complement-dependent cytotox
215 nulation pathway, but not antibody-dependent cell-mediated cytotoxicity, contribute to the superior c
218 killer and lymphokine-activated killer (LAK) cell-mediated cytotoxicity for G-CSF-mobilized effector
220 t depletes eosinophils by antibody-dependent cell-mediated cytotoxicity, for patients with severe, un
221 ressing cells were resistant to Ab-dependent cell-mediated cytotoxicity, formed no syncytia, and neit
225 to be capable of inducing antibody-dependent cell-mediated cytotoxicity in ABCB5+ MMIC, exerted tumou
226 me B (GzmB) is a serine protease involved in cell-mediated cytotoxicity in conjunction with the pore-
227 ia upregulation of PD-L1, and reduced CD8+ T-cell-mediated cytotoxicity in HMGB1/TBK1/IRF3/NF-kappaB-
228 data demonstrate a dominant role of CD4(+) T cell-mediated cytotoxicity in plasmid DNA vaccine antige
229 variants demonstrated no antibody-dependent cell-mediated cytotoxicity in vitro against Daudi cells
230 lular phagocytosis and/or antibody-dependent cell-mediated cytotoxicity in vitro Our antibodies, spec
236 IFN-gamma-deficient mice, we show that CD4 T cell-mediated cytotoxicity in vivo is not dependent on I
237 is a potent regulator of antibody-dependent cell-mediated cytotoxicity in vivo, modulating the activ
238 ammaRIIB showed much more antibody-dependent cell-mediated cytotoxicity; in contrast, mice deficient
239 cell clearance, NKG2D- or antibody-dependent cell-mediated cytotoxicity-induced tumor cell cytotoxici
241 signaling inhibition with antibody-dependent cell-mediated cytotoxicity induction and results in supe
245 Nanowell Grids to analyze antibody-dependent cell-mediated cytotoxicity kinetics of thousands of indi
246 and that TRAIL deficiency decreases CD8(+) T cell-mediated cytotoxicity, leading to more severe influ
249 of self proteins, GrB-cleaved TAL-specific T cell-mediated cytotoxicity may contribute to the progres
250 ndent mechanisms, such as antibody-dependent cell-mediated cytotoxicity, may be involved in the in vi
251 tralising antibodies, and antibody-dependent cell-mediated cytotoxicity measured 2 weeks after the mo
252 y both complement-dependent and Ab-dependent cell-mediated cytotoxicity mechanisms; the CD8+ cells do
253 ed robust, cross-reactive antibody-dependent cell-mediated cytotoxicity-mediating and neuraminidase-i
256 mplement-dependent cytolysis or Ab-dependent cell-mediated cytotoxicity of immortalized human hepatoc
258 mAb induced phagocytosis and natural killer cell-mediated cytotoxicity of TCL cells that was augment
259 extent, IMC-NC7 initiated antibody-dependent cell-mediated cytotoxicity on FLT3-expressing cells.
260 and therefore does not mediate Ab-dependent cell-mediated cytotoxicity or modulation/loss of CD4 fro
261 neutralization activity, antibody-dependent cell-mediated cytotoxicity, or HIV-1 envelope-specific I
262 a by NK cells in the context of Ab-dependent cell-mediated cytotoxicity (p = 0.039) and increased deg
263 ng genes, including eight involved in the NK cell-mediated cytotoxicity pathway, impairs lymphokine-a
271 d IgG3 subclass mediating antibody-dependent cell-mediated cytotoxicity, seem to play a predominant r
272 e often associated with inherited defects in cell-mediated cytotoxicity, serves as a prototypical CSS
274 iciency disorder characterized by defects in cell-mediated cytotoxicity that results in fever, hepato
275 receptor of the CD2 family that triggers NK cell-mediated cytotoxicity through an undefined signalin
276 ndergoing mAb therapy via antibody-dependent cell-mediated cytotoxicity, thus explaining the potent "
277 were capable of inducing antibody-dependent cell-mediated cytotoxicity to autologous and allogeneic
278 In vitro, AT1413 bTCE efficiently induced T-cell-mediated cytotoxicity toward different AML cell lin
280 hown to elicit a level of antibody-dependent cell-mediated cytotoxicity toward human neuroblastoma ce
281 n vitro analyses confirmed the presence of T cell-mediated cytotoxicity toward the breast cancer cell
282 s of kindlin-3 has a pronounced effect on NK cell-mediated cytotoxicity triggered by single activatin
283 nhibition of signaling pathways, but also by cell-mediated cytotoxicity triggered by the infused TA-t
284 tion of each of these exchange factors to NK cell-mediated cytotoxicity using mice lacking one, two,
289 ther investigate the function of NKLAM in NK cell-mediated cytotoxicity, we generated, by gene target
290 thways, activation of apoptosis and effector-cell-mediated cytotoxicity, we show here that engagement
291 tokine-cytokine receptor interactions and NK cell-mediated cytotoxicity were down-regulated in cKO de
292 and MICB genes related to antibody-dependent cell-mediated cytotoxicity were identified in tumors wit
293 yeloid effector cells for antibody-dependent cell-mediated cytotoxicity, were similar between wild-ty
295 on of IgG via CD16a and execute Ab-dependent cell-mediated cytotoxicity, which is critical for the ef
296 ontrast, Cbl-b deficiency minimally affected cell-mediated cytotoxicity, which requires limited engag
297 nd blocked NMO-IgG-dependent complement- and cell-mediated cytotoxicity with IC(50) down to approxima
298 transplantation vasculopathy is initiated by cell-mediated cytotoxicity with its perpetuation facilit
299 m reduced by >95% CDC and antibody-dependent cell-mediated cytotoxicity, without impairment of NMO-Ig
300 latively competent for ITAM receptor-induced cell-mediated cytotoxicity, yet completely deficient for