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1 ed DNA damage in human cells are affected by cellular context.
2 characterization of proteins in their native cellular context.
3 erstanding of the function of a protein in a cellular context.
4 ocytosis in varying degrees depending on the cellular context.
5 ation is poorly defined, particularly in the cellular context.
6 nd growth, contingent upon the molecular and cellular context.
7 s in tumor progression that are dependent on cellular context.
8 profile numerous RNA species in their native cellular context.
9 to understand gene function in a particular cellular context.
10 ss or promote tumorigenesis depending on the cellular context.
11 his organelle and to probe its behavior in a cellular context.
12 ization and interaction networks in a native cellular context.
13 aling and neuronal glucose metabolism in the cellular context.
14 ponding full-length proteins in their native cellular context.
15 on both the brightness of the focus, and the cellular context.
16 ecome active enhancers given the appropriate cellular context.
17 long non-coding RNAs (lncRNAs) in the native cellular context.
18 ure to optimize metabolic processes within a cellular context.
19 ppressor or tumour promoter depending on the cellular context.
20 e clock fits within and influences a broader cellular context.
21 f what can constitute an active protein in a cellular context.
22 ulatory activity in a co-transcriptional and cellular context.
23 B isoforms and modulation of the target in a cellular context.
24 d what functional roles they play depends on cellular context.
25 ously appreciated and is highly dependent on cellular context.
26 nd anti-tumorigenic signaling depending upon cellular context.
27 nts also shows the same selectivity within a cellular context.
28 ligands that target G-quadruplexes within a cellular context.
29 that Rasip1 interacts with active Rap1 in a cellular context.
30 ng activities are likely to be relevant in a cellular context.
31 s and paths under specific environmental and cellular context.
32 or suppress signaling depending on the local cellular context.
33 f deleterious consequences, depending on the cellular context.
34 target one of the eleven human caspases in a cellular context.
35 d interpretation of nuclear transport in the cellular context.
36 alysis of the viral replication steps in the cellular context.
37 cer is complex and may vary depending on the cellular context.
38 ner strictly dependent by its expression and cellular context.
39 ctional role in macromolecular activity in a cellular context.
40 chaperones by altering the environment in a cellular context.
41 and requires just one receptor regardless of cellular context.
42 ficity of smAKAP for PKA-RIalpha/beta in the cellular context.
43 eins with respect to one another in a native cellular context.
44 impairment of RET activity depending on the cellular context.
45 l death or differentiation, depending on the cellular context.
46 hoid and myeloid progenitors autonomously of cellular context.
47 mechanisms driving membrane deformation in a cellular context.
48 mall ensembles or behave processively in the cellular context.
49 r Cyclin B in regulating replication in this cellular context.
50 bit tumourigenic processes, depending on the cellular context.
51 nd anti-metastatic function depending on the cellular context.
52 or suppressive or oncogenic depending on the cellular context.
53 e or inhibit tumorigenesis, depending on the cellular context.
54 ctions of proteins expressed in their native cellular context.
55 strains of mice to be placed into a coherent cellular context.
56 ts or promotes angiogenesis depending on the cellular context.
57 icity of complex formation in vitro and in a cellular context.
58 ein molecules both in isolation and in their cellular context.
59 posing mechanisms of action depending on the cellular context.
60 uctures of macromolecular complexes in their cellular context.
61 nction of individual enzymes in their native cellular context.
62 M cell line to validate this dependence in a cellular context.
63 hancer to NICD thus differs depending on the cellular context.
64 d by validating our structural findings in a cellular context.
65 mporal control of peptide assemblies, in the cellular context.
66 ial bacterial thymidylate synthase ThyX in a cellular context.
67 experiments are not carried out in a native cellular context.
68 chemical environment of RNA coacervates in a cellular context.
69 ively regulate cystogenesis depending on the cellular context.
70 ble quantification of antibody blockade in a cellular context.
71 cules, but the reconstructions lack detailed cellular context.
72 he heterogeneity of the chaperome in a given cellular context.
73 lization of individual biomolecules within a cellular context.
74 outcomes being dependent on both timing and cellular context.
75 mic infection in a physiologically relevant, cellular context.
76 GRP78 and that both proteins interact in the cellular context.
77 ng of transcription factors (TFs) in a given cellular context.
78 cles act as landmarks and offer clarity in a cellular context.
79 factor receptor-bound protein 2 (Grb2) in a cellular context.
80 entified were also active enhancers in other cellular contexts.
81 ynamically during differentiation and across cellular contexts.
82 e variants in their physiologically relevant cellular contexts.
83 enzyme and a signaling cofactor in different cellular contexts.
84 ic and anti-oncogenic phenotypes in specific cellular contexts.
85 ionarily conserved genetic module in diverse cellular contexts.
86 ts precise gene expression levels in varying cellular contexts.
87 ys to monitor DUB activities in vitro and in cellular contexts.
88 s in cell-to-cell communication in different cellular contexts.
89 ell models, encompassing hepatic and mammary cellular contexts.
90 of protein-specific glycosylation in various cellular contexts.
91 hances the loss of miRNA function in diverse cellular contexts.
92 portant transcriptional regulator in diverse cellular contexts.
93 he engineering of BMCs for new functions and cellular contexts.
94 sensor of mechanical stimulation in diverse cellular contexts.
95 r capable of membrane remodeling in multiple cellular contexts.
96 hinery for contraction that acts in multiple cellular contexts.
97 and and outwit adaptation in a wide range of cellular contexts.
98 utant Puma on cell viability in a variety of cellular contexts.
99 6A enzymatic activity is required in certain cellular contexts.
100 ed within most physiological or pathological cellular contexts.
101 mine GATA1 function in biologically relevant cellular contexts.
102 cting partners of target proteins in diverse cellular contexts.
103 n cycles, pathways, and networks in multiple cellular contexts.
104 gulation of a target transcript in different cellular contexts.
105 ntify energy metabolism in a wide variety of cellular contexts.
106 he function of specific cells within complex cellular contexts.
107 s share signalling pathways across different cellular contexts.
108 of endogenous methyltransferases in diverse cellular contexts.
109 pact on stimulus-secretion coupling in wider cellular contexts.
110 e accurate and restricted to the appropriate cellular contexts.
111 ance of studying miRNA function in different cellular contexts.
112 displaces transcription ECs in a variety of cellular contexts.
113 by analyzing chromatin features in different cellular contexts.
114 such reiteratively used factors in different cellular contexts.
115 and critical component of the PQC in several cellular contexts.
116 ling of a given perturbation across multiple cellular contexts.
117 ectivity of regulatory networks in different cellular contexts.
118 hysiological responses observed in different cellular contexts.
119 iated double-strand breaks (DSBs) in several cellular contexts.
120 bly may regulate the cytoskeleton in dynamic cellular contexts.
121 onal redundancy for PKD1 and PKD2 in various cellular contexts.
122 ogen-derived stimuli in immune and nonimmune cellular contexts.
123 tinct processes in the same and/or different cellular contexts.
124 the direct binding of PPARgamma in different cellular contexts.
125 y the effects of m(6)A can vary in different cellular contexts.
126 affect compound efficacy in biochemical and cellular contexts.
127 ion of chromatin dynamics across 123 diverse cellular contexts.
128 mpounds that increase SMN protein in various cellular contexts.
129 tein recruitment and localization in several cellular contexts.
130 multiple biochemical functions in different cellular contexts.
131 ermines NRF member activation under specific cellular contexts.
132 amine 3D genome organization across multiple cellular contexts.
133 agy presides over life and death in specific cellular contexts.
134 wide chromatin accessibility profiles across cellular contexts.
135 ch TF to control gene expression in specific cellular contexts.
136 network is precisely controlled in different cellular contexts.
137 red following ligand engagement in different cellular contexts.
138 umor suppressive functions acting in diverse cellular contexts.
139 tablishing excitable actin dynamics in other cellular contexts.
140 ould be propagated as hereditary material in cellular contexts.
143 mic elements, these results suggest that the cellular context also determines susceptibility to PyV m
144 tions of complex molecular machines in their cellular context and at atomic resolution is of prime im
148 chain precedes disulfide formation within a cellular context and highlights key differences between
149 ly, we discuss disulfide bond formation in a cellular context and identify important principles that
150 ne networks driving asthma, placing these in cellular context and incorporating insights from cytokin
151 olution, and underline the importance of the cellular context and integrated approaches for understan
152 assumes opposite functions depending on the cellular context and its posttranslational modifications
153 permethylation vary greatly according to the cellular context and may help explain why IDH(mut) is on
154 xical, effects on viability depending on the cellular context and that EphA2 mediates a delicate bala
156 iption in a manner that is dependent on both cellular context and the specific downstream target.
160 ole of space and spatial control in multiple cellular contexts and a basis for engineering spatial co
162 protein PARylation by 3'-azido NAD(+) in the cellular contexts and facilitate direct visualization an
166 dimerization is a critical step in multiple cellular contexts and plays a key role in resistance.
168 on of FGF2 mediated by Tec in vitro and in a cellular context, and (iii) unconventional secretion of
169 G protein signaling of CXCR4 depends on the cellular context, and discrepancies exist depending on t
171 assay was used to validate the results in a cellular context, and peptide insertions were modeled us
172 this bias can vary depending on location and cellular context, and that DSB frequency is not the only
173 ponse threshold is determined by the rGC and cellular context, and that multiple domains contribute t
174 n of reiteratively used factors in different cellular contexts, and an important strategy for doing s
175 t both because it is encountered in concrete cellular contexts, and because it serves as a bridge bet
176 xpressed, autophagy can occur in specialized cellular contexts, and mechanisms underlying cell-type-s
177 unctional adaptability of Smads in different cellular contexts, and their dependence on lineage-deter
178 ansformation in virtually all cell types and cellular contexts, aneuploidy is not a universal promote
179 accessibility and gene expression in diverse cellular contexts are critical to decipher the dynamics
180 eolytic activity; and that, depending on the cellular context, Atg7 represses the apoptotic capabilit
183 somal fusion have not been verified within a cellular context because of difficulties with assessing
185 he Notch pathway on proliferation depends on cellular context, being growth promotion in some, includ
186 led that the dyes are functional in multiple cellular contexts, both on the cell surface and within t
187 mosome movement during anaphase in different cellular contexts, but how these activities are achieved
188 ains of SALS with actin must be tuned in the cellular context by other modules of the protein and/or
190 gested as an eat-me signal in dead and dying cellular contexts, can also promote phagocytic uptake of
192 acterization confirmed high dual efficacy in cellular context combined with low toxicity, and pilot i
194 ly on their local genomic environment and on cellular context, complicating experimental analysis of
196 ns of membrane-permeant small molecules in a cellular context could facilitate development of site-di
198 ted with human cancers and Tp53 deletion has cellular context dependent effects upon lymphocyte trans
201 Galectins are proteins involved in diverse cellular contexts due to their capacity to decipher and
204 inactivation of ARF and reveal an important cellular context for genetic and viral inactivation of T
205 at GR is required to establish the necessary cellular context for maintaining normal uterine biology
206 tted B-progenitor might provide a permissive cellular context for prenatal B-progenitor leukemia init
207 affect gene expression can vary in different cellular contexts, for example between different subtype
208 lipids in single extracts, lose the original cellular context from which these lipids are derived.
210 uncoupling cell size from a developmental or cellular context has proven experimentally challenging.
213 are elicited by Wnt stimulation in different cellular contexts; however, mechanisms that confer conte
216 development-with its resulting diversity of cellular contexts-impacts miRNA regulation is unclear.
218 er, our findings highlight the importance of cellular context in assigning growth properties to growt
219 eurons and that highlights the importance of cellular context in determining the effects of signal pa
222 demonstrate the importance of molecular and cellular context in oncogenic transformation and acquisi
225 uences of their signaling crosstalk in multi-cellular context in vivo remain largely unknown, especia
226 However, they cannot directly inform the cellular context in which disease-associated variants ac
230 ologous genes is primarily determined by the cellular context in which the genes act, explaining why
231 al selectivity of Mur and Fur depends on the cellular context in which they function, not on intrinsi
233 ensitive to functional inhibition by SC66 in cellular contexts in which the PI3K inhibition has littl
234 eolysis in two entirely distinct protein and cellular contexts, in one case participating in bacterio
235 he establishment of cell polarity in various cellular contexts, including axis-pattern formation in t
236 ral to establishing cell polarity in various cellular contexts, including during messenger ribonuclei
237 rotein PAR-1 plays an essential role in many cellular contexts, including embryogenesis, asymmetric c
241 o their contribution to protein binding in a cellular context is applicable to other transcription fa
243 R and FOXA1 binding events in drug-resistant cellular contexts is supported by histological co-expres
245 m this study highlight the importance of the cellular context of different cancer cells for the funct
246 ons suggest that the duration, intensity and cellular context of FGFR signaling during growth plate c
252 sed the impact of epigenetic alterations and cellular context on functional and transcriptional repro
254 hose binding sites that are sensitive to the cellular context or post-translational modifications, an
255 nstrated here may be critical in WNT4-driven cellular contexts or in those that are considered to hav
256 recognition receptor signaling under certain cellular contexts, or in response to some viral and bact
257 observe may be dependent on experimental or cellular context, our results suggest that gene promoter
260 Our results indicate that within the same cellular context, RAS can exert different, even antagoni
261 sults reveal a regulatory principle by which cellular context regulates Akt protein dynamics, which d
263 ing their differential binding sites between cellular contexts requires a rigorous comparison of the
265 veal general principles for the formation of cellular context-specific functions and elucidate potent
266 a damage-gated molecular switch that governs cellular-context-specific cell fate decisions in respons
267 at interpret an enhancer sequence in a given cellular context specified by transcription factor conce
268 ome of enhanced gene disruption depends upon cellular context, stimulating deletion of genomic sequen
269 principle experiments demonstrated that in a cellular context, SUBINs largely prevent heat shock-trig
271 he body; it has different roles in different cellular contexts, such as oncogenic and tumor-suppresso
272 tween 2D and three-dimensional adhesion in a cellular context, supporting the hypothesis of natural k
273 ly modulating p53 activity, Oct-4 provides a cellular context that augments the proapoptotic activity
276 y osteolysis, but regardless of etiology and cellular contexts, the osteoclast is the bone-degrading
277 made in defining the role of APC in a normal cellular context, there are still significant gaps in ou
278 pecific regulatory factors in many different cellular contexts, thereby revealing the fundamental pri
279 ontaining ETS or AP1 motifs depending on the cellular context, thus indicating new approaches for mod
280 lling for a detailed characterization of the cellular context to fully comprehend HIF-1's role in tum
281 ually complementary roles that use LLPS in a cellular context to implement emergent functionalities t
282 the application of stabilizing ligands in a cellular context to target G-quadruplexes and intervene
284 -heterodimer PfCCT protein in a heterologous cellular context using the thermosensitive CCT-mutant CH
286 fficiency to quantify protein copy number in cellular contexts using super-resolution microscopy.
287 ectrode surface, mimicking TLR-4's role in a cellular context, was essential in producing a responsiv
288 3D arrangement of prion assemblies in their cellular context, we examined yeast [PSI(+)] prions in t
289 reactive oxygen species (ROS) in its native cellular context, we now present a new method for monito
293 of genetic regulation of gene expression by cellular context, which relates to cell-type-specific DN
295 lk, our work indicates that consideration of cellular context will likely be crucial for targeting si
296 a stable form that RNAP III can access in a cellular context with, in some cases, near promoter-like
298 nsights into how proteins are organized in a cellular context, with a spatial resolution approaching
299 ferent biological roles depending upon their cellular context, with BD2 particularly associated with
300 oscopic images of specific proteins in their cellular context yield important insights into biologica