ライフサイエンスコーパス: cellular immune response

1 ved resistance by developing a more reactive cellular immune response.

2 several years to be important in shaping the cellular immune response.

3 erapy show signs of a particularly efficient cellular immune response.

4 antioxidants and offspring that had reduced cellular immune response.

5 echnique did, however, provoke a significant cellular immune response.

6 -HDM induced an antibody response, besides a cellular immune response.

7 d tumor death induces a long-term anti-tumor cellular immune response.

8 emic infection and that this depended on the cellular immune response.

9 ificant effects of ISG15 modification on the cellular immune response.

10 cium burst is required for activation of the cellular immune response.

11 TBE high responders in terms of humoral and cellular immune response.

12 ule that is used to study both facets of the cellular immune response.

13 1 immune polarization and activation of the cellular immune response.

14 r at distal sites and instead had an altered cellular immune response.

15 l receptor (TCR) is a key determinant of the cellular immune response.

16 primary infection, thereby compromising the cellular immune response.

17 adaptive immune cells, while modulating the cellular immune response.

18 le safety profile and stimulated humoral and cellular immune responses.

19 y of the decidua to mount appropriate innate cellular immune responses.

20 NA vaccination influences the quality of the cellular immune responses.

21 t subset of pDCs specialized in coordinating cellular immune responses.

22 ct type III IFN signaling and virus-specific cellular immune responses.

23 ed and elicited antigen-specific humoral and cellular immune responses.

24 the complexity of the mechanisms regulating cellular immune responses.

25 +) T cells mediate antigen-specific adaptive cellular immune responses.

26 vel type of vaccine elicits both humoral and cellular immune responses.

27 C is critical for the effective induction of cellular immune responses.

28 agglutinin antibody responses, but different cellular immune responses.

29 mmunological synapse formation, and numerous cellular immune responses.

30 a-tumor heterogeneity and dissecting complex cellular immune responses.

31 ion of additional genes that are involved in cellular immune responses.

32 ed the induction of SIV-specific humoral and cellular immune responses.

33 ylceramide adjuvant, though adjuvant reduced cellular immune responses.

34 in the T4 head elicited robust antibody and cellular immune responses.

35 as the detection of Ag-specific humoral and cellular immune responses.

36 ncluding downregulation of cytokine-mediated cellular immune responses.

37 ellular pathogens requires the generation of cellular immune responses.

38 he magnitude and duration of both innate and cellular immune responses.

39 accine candidates targeting both humoral and cellular immune responses.

40 l transmission may require IgA antibodies or cellular immune responses.

41 purified, and used for the human humoral and cellular immune responses.

42 OV insert induce strong, durable humoral and cellular immune responses.

43 essential for the development of humoral and cellular immune responses.

44 is a strong adjuvant capable of stimulating cellular immune responses.

45 ion representing the extremes of humoral and cellular immune responses.

46 HHV-6 and provide a basis for tracking HHV-6 cellular immune responses.

47 re treated with TSLP and antigen to evaluate cellular immune responses.

48 f contaminating linear RNA leading to robust cellular immune responses.

49 mice results in strong antiviral humoral and cellular immune responses.

50 MGN1703 dosing, suggesting an enhancement of cellular immune responses.

51 ut rather is due to compromised local innate cellular immune responses.

52 tes because they can elicit both humoral and cellular immune responses.

53 ogous Ad26,Ad26 regimens induced humoral and cellular immune responses 21 days post-dose 2; responses

54 characterized by an exaggerated humoral and cellular immune response affecting the small airways and

55 blood mononuclear cells mounted a negligible cellular immune response after stimulation with saliva.

56 y profile and elicited sustained humoral and cellular immune responses after a single immunization in

57 has been associated with quicker recovery of cellular immune responses after ART initiation and early

58 pression, and enhanced primary and secondary cellular immune responses after mCMV infection than did

59 particularly gammadelta T cells) in the host cellular immune response against AIM and CAEBV.

60 a1-15 or Abeta1-40/42 peptides, indicating a cellular immune response against DT while avoiding an Ab

61 h p24-SIgA elicits both a strong humoral and cellular immune response against p24 at the systemic and

62 ells that sense DV infection and amplify the cellular immune response against this virus in an IL-18-

63 and FIX concentrate use, without detectable cellular immune responses against capsids.

64 of arthritis were recorded, and humoral and cellular immune responses against CII were analyzed.

65 In addition, humoral and cellular immune responses against EBOV glycoprotein were

66 Here, we investigated whether cellular immune responses against HIV-1 include such T m

67 Mice generated both humoral and cellular immune responses against JCV.

68 Cellular immune responses against NS5 were also elicited

69 Ebola VLP vaccine elicits strong humoral and cellular immune responses against pathogenic Ebola virus

70 ctivate the innate immune system and improve cellular immune responses against rAd5-expressed Ags, in

71 mory T cells in cancer patients for studying cellular immune responses against SARS-CoV-2.

72 accination with ENO1 DNA elicits humoral and cellular immune responses against tumors, delays tumor p

73 of truncated variants in the major target of cellular immune responses all parallel what are seen wit

74 cant enrichment of nervous system signaling, cellular immune response and cytokine signaling pathways

75 proteins responsible for the aforementioned cellular immune response and IFN-gamma production.

76 on of an epithelial tissue, viral infection, cellular immune response and tissue damage, specifically

77 HVEM regulates cellular immune responses and can also increase cell sur

78 ally and systemically via stimulation of CD8 cellular immune responses and highlight a conserved role

79 engineered CHO cells exhibited activation of cellular immune responses and increased resistance to th

80 of HIV-specific T-cell immunity and identify cellular immune responses and individual cytokines as po

81 lly with coated spores developed humoral and cellular immune responses and multifunctional T cells an

82 s have investigated the protective effect of cellular immune responses and neuraminidase-inhibiting a

83 noregulatory capacity through suppression of cellular immune responses and production of anti-inflamm

84 ass of vaccine adjuvants capable of inducing cellular immune responses and protective efficacy agains

85 ty of our candidate dengue vaccine to elicit cellular immune responses and support the further evalua

86 sults from this study reveal the humoral and cellular immune responses and the protective effects con

87 We aimed to define anti-ADH cellular immune responses and their association with act

88 clearance, subsequent emergence of a potent cellular immune response, and the effect of these on liv

89 viral load or in the magnitude of antiviral cellular immune response, and there was no clinical impr

90 Antibody, cellular immune responses, and epitope specificity in se

91 data on strength or duration of humoral and cellular immune responses, and on vaccine efficacy or va

92 per and lower respiratory tract, humoral and cellular immune responses, and pathologic evidence of vi

93 acid sequences that are the major targets of cellular immune responses, and the emergence in vivo of

94 cination induced potent innate, humoral, and cellular immune responses, and the mutant could protect

95 mistry and sexual hormone levels and reduced cellular immune response, antioxidant levels, and carote

96 Innate cellular immune responses are a critical first-line defe

97 racellular pathogens, where both humoral and cellular immune responses are desired.

98 ely aspect of this failure is that antiviral cellular immune responses are either absent or present a

99 We conclude that local cellular immune responses are important for protection a

100 Cellular immune responses are not well characterized dur

101 e, suggesting that the age-associated skewed cellular immune responses are reversible.

102 Humoral and cellular immune responses are seen in both models after

103 Broadly targeted cellular immune responses are thought to be important fo

104 While humoral and cellular immune responses are well described in peripher

105 d insights into the hemocyte development and cellular immune responses at single-cell resolution.

106 We hypothesized that innate cellular immune responses at the site of infection would

107 not appear to be required to counteract the cellular immune response but are needed for the coloniza

108 facilitates lytic infection, modulating the cellular immune response by interacting with viral and c

109 we show that bacterial infection induces the cellular immune response by modulating occluding-junctio

110 the HSV-1 LAT locus interferes with the host cellular immune response by shaping a broader repertoire

111 e Varroa mite, adversely affects humoral and cellular immune responses by interfering with NF-kappaB

112 ggest that IL-33 attenuates the induction of cellular immune responses by nanoparticulate adjuvants a

113 es an ability to potently induce humoral and cellular immune responses by use of highly attenuated an

114 orm new antigens, to which a humoural and/or cellular immune response can develop.

115 tered to adult mice(7); however, humoral and cellular immune responses can be avoided by treating neo

116 potent functional neutralizing antibody and cellular immune responses, characterized by HA-specific

117 cination with VC2-EHV-1-gD stimulated strong cellular immune responses, characterized by the upregula

118 It is unknown to what extent cellular immune responses contribute to liver disease an

119 Thus, insufficient innate cytokine and cellular immune responses contribute to the unique susce

120 s in unvaccinated individuals, when a strong cellular immune response controls early infection.

121 The breadth of cellular immune responses correlated inversely with set

122 ture and, following infection, flies mount a cellular immune response culminating in the cellular enc

123 ssessing the risk of CMV infection, although cellular immune responses driven by CMV-specific CD4 and

124 esenting a unique opportunity to examine the cellular immune responses during acute Ebola virus infec

125 This study demonstrates that cattle mount cellular immune responses during colonization with EHEC

126 To characterize cellular immune responses during recovery, we analyzed t

127 aracterize in greater detail the humoral and cellular immune responses elicited by Ad26.ENVA.01 in hu

128 The humoral and cellular immune responses elicited by the trivalent live

129 Therefore, the cellular immune response evolves during MeV clearance to

130 CD8(+) T cells and are essential for optimal cellular immune responses following immunization with pl

131 studies reporting on measles virus-specific cellular immune responses found that T-cell responses an

132 We now characterize the cellular immune response from 20 donors against 5 major

133 Similarly, cellular immune responses from a subset of subjects and

134 igens are used as a surrogate for endogenous cellular immune responses generated during infection.

135 the success and failure of the HIV-specific cellular immune response has implications that extend no

136 spp., where protection is likely mediated by cellular immune responses, has proven elusive.

137 n and vaccination, efforts to understand the cellular immune response have been severely hampered by

138 l trials have shown that both antibodies and cellular immune responses have been correlated with prot

139 Cellular immune responses have been repeatedly associate

140 10 and their overall influence on innate and cellular immune responses have not been well characteriz

141 Cellular immune responses have the potential to elicit d

142 the MNP boost showed significantly enhanced cellular immune responses, hemagglutination-inhibition (

143 Refractory cellular immune responses, immunosuppression-linked infe

144 gest that this property influences antiviral cellular immune responses.IMPORTANCE Primate lentiviruse

145 The induction of a potent humoral and cellular immune response in mucosal tissue is important

146 apies and vaccines for HIV-1 but also to the cellular immune response in other disease states.

147 We analyzed the cellular immune response in spleens from PIV- and PIIV-v

148 To assess the viral targets of the cellular immune response in STLV-1-infected animals, we

149 No data are available on the cellular immune response in the acute phase of human ZIK

150 Detailed analysis of the cellular immune response in tumours has the potential to

151 type humoral immune responses in 40%-50% and cellular immune responses in 50%-75% of follicular lymph

152 There is little information on cellular immune responses in asymptomatic parasite carri

153 Here we describe cellular immune responses in baboons against a closely r

154 Several studies have investigated cellular immune responses in COVID-19-infected patients

155 via lymph is critical for the generation of cellular immune responses in draining lymph nodes (LNs).

156 crobial pathogens involves the activation of cellular immune responses in eukaryotes, and this cellul

157 monstrate here the induction of SIV-specific cellular immune responses in foreskin by adenovirus sero

158 ygosity and protective antigen (PA)-specific cellular immune responses in healthy subjects following

159 ed breadth and magnitude of MHC-B-restricted cellular immune responses in HIV-infected individuals.

160 the RSV-specific human innate, humoral, and cellular immune responses in humanized mice (mice with a

161 01 elicited a broad diversity of humoral and cellular immune responses in humans.

162 etry enables highly multiplexed profiling of cellular immune responses in limited-volume samples, adv

163 This vaccine stimulated strong humoral and cellular immune responses in mice, suggesting that it co

164 Nonlive vaccine platforms that induce potent cellular immune responses in mucosal tissue would have b

165 All regimens elicited humoral and cellular immune responses in nearly all participants.

166 ay of birth elicited detectable Gag-specific cellular immune responses in rhesus monkeys, but these r

167 ic role of CD39 in the kinetic regulation of cellular immune responses in the evolution of disease.

168 Also, there were enhanced cellular immune responses in the group received adjuvant

169 rowth transforming ability, induces multiple cellular immune responses in the infected host.

170 o generate a safe replicative body to escape cellular immune responses in the insect gut.

171 ystemic and mucosal Env-specific humoral and cellular immune responses in the majority of subjects.

172 study, we compared antiparasite humoral and cellular immune responses in two cohorts of malaria-naiv

173 in the magnitude and breadth of SIV-specific cellular immune responses in virologically suppressed, S

174 y suitable for non-invasive field studies of cellular immune responses in wild large mammals.

175 ncing is enabling deep explorations into the cellular immune response, including the characterization

176 ary coccidioidomycosis demonstrated specific cellular immune responses, including expression of IL-17

177 Vaccinated animals developed humoral and cellular immune responses, including neutralizing antibo

178 bust SARS-CoV-2 antigen-specific humoral and cellular immune responses, including potent neutralizing

179 this study were: 1) to quantify the in vivo cellular immune response induced by AS01 in an outbred o

180 Here, we analyzed human cellular immune responses induced by a single dose of th

181 ME or 12,13-EpOME into larvae suppressed the cellular immune responses induced by bacterial challenge

182 Env-specific cellular immune responses induced by the vaccine include

183 tages in a vaccine setting, eliciting strong cellular immune responses involving both CD8(+) and CD4(

184 It is known that vigorous and multispecific cellular immune responses, involving both helper CD4(+)

185 preservation or restoration of HIV-specific cellular immune response is a major goal of AIDS treatme

186 Although the host cellular immune response is critical to the control of t

187 ppling the immune system before an effective cellular immune response is developed and active.

188 JCV-specific cellular immune response is highly prevalent in all JCV-

189 findings show that the induction of a strong cellular immune response may limit antibody responses in

190 Thus, the factors defining protective cellular immune responses may be more complex than simpl

191 tanding the coordination between humoral and cellular immune responses may be the key to developing p

192 inst SARS-CoV-2 in rhesus macaques, and that cellular immune responses may contribute to protection i

193 Cellular immune responses measured by flow cytometry wer

194 which are not sufficient for augmenting the cellular immune response, notably, HVRs I, II, and V.

195 The cellular immune responses observed in the lower airways

196 ls (Tregs) are an essential component of the cellular immune response, occupying a key role in mainta

197 We then characterized the cellular immune response of 59 cases of POT and 4 cases

198 oost regimen) induced a balanced humoral and cellular immune response of type-1 and type-2 T helper c

199 m future vaccine development, we studied the cellular immune responses of cattle during EHEC O157:H7

200 nefit from the induction of both humoral and cellular immune responses of maximal breadth, potency, a

201 d HIV-1 sequences that are aimed at focusing cellular immune responses on these potentially critical

202 modeling, arrhythmogenicity, activation of a cellular immune response, or off-target organ damage by

203 The cellular immune response plays a critical role in contro

204 We first show that the cellular immune response plays an important role in regu

205 sion of NASH by stimulating both humoral and cellular immune responses, pointing to the possible role

206 by robust induction of adaptive humoral and cellular immune responses postvaccination and postchalle

207 nd examined recipients' CMV antigen-specific cellular immune responses primed directly by donor cells

208 notype, and polyfunctional pathogen-specific cellular immune responses prior to and 4 weeks after ART

209 We propose that cellular immune responses reduce the threshold of nAbs r

210 Mucosal and cellular immune responses remain poorly understood, with

211 egulatory elements, their role in modulating cellular immune responses remains poorly understood.

212 e human subjects, eliciting both humoral and cellular immune responses (S.

213 ocking IgG antibodies and alterations of the cellular immune response so that the patient can tolerat

214 a biochemistry, carotenoid-based coloration, cellular immune response, steroid hormone levels, and re

215 he most likely reasons that the HIV-specific cellular immune response succeeds in a small number of p

216 Surprisingly, other innate cellular immune responses, such as phagocytosis, are dra

217 critical physiological processes, including cellular immune responses, such as survival of Th17 cell

218 ether with the induction of both humoral and cellular immune responses, support large-scale evaluatio

219 l loads and earlier and stronger humoral and cellular immune responses than controls.

220 ion, WT mice mounted more robust humoral and cellular immune responses than HLA-DR4 mice.

221 geneic glioma models involves a multifaceted cellular immune response that can be overcome with cyclo

222 theless, all animals generated a humoral and cellular immune response that conferred partial cross-pr

223 that model further, we uncovered an altered cellular immune response that promotes the recruitment o

224 oach is to design a vaccine that will elicit cellular immune responses that are focused on highly con

225 Further, gL-minus RRV elicits cellular immune responses that are predominantly canonic

226 The somatic co-evolution of tumors and the cellular immune responses that combat them drives the di

227 wever, the role that hBDs have in initiating cellular immune responses that contribute to antigen-spe

228 cal screening are targets of multifunctional cellular immune responses that correlate with protection

229 Cellular immune responses that protect against tumors ty

230 Understanding the cellular immune responses that regulate viral replicatio

231 iators provides a link between metabolic and cellular immune responses that result in the Th1-mediate

232 The HIV SAM vaccine induced potent cellular immune responses that were greater in magnitude

233 ral gene product that is the major target of cellular immune responses, the persistence of viral amin

234 bacteria, and protozoan parasites, suppress cellular immune responses through activation of type I I

235 B cells control cellular immune responses through cell-cell contact, ant

236 We now characterize the cellular immune response to all 7 PIV3-encoded antigens

237 fection in the middle ear (ME), but the host cellular immune response to bacterial infection in this

238 amma (IFNgamma) ELISpot assays to assess the cellular immune response to blood-stage and pre-erythroc

239 deficient mice exhibit an intact humoral and cellular immune response to collagen and yet have a redu

240 The cellular immune response to HIV-1 has now been studied i

241 ls represent a long-lasting component of the cellular immune response to HIV-1 that persists in an an

242 Tissue damage is attributed to the cellular immune response to HTLV-1-infected lymphocytes.

243 sensing of viral DNA is an essential step of cellular immune response to infections with DNA viruses.

244 g IFN-gamma and IL-17A production during the cellular immune response to M. tuberculosis.

245 A-heterozygous individuals generate stronger cellular immune response to other virulence factors (Bac

246 n of Ag-specific memory Tregs that shape the cellular immune response to secondary influenza virus ch

247 Thus, we characterized the cellular immune response to the virus and identified F,

248 cellular immunity, we wanted to compare the cellular immune response to this challenge strain to the

249 Understanding the cellular immune response to this infection is important

250 or hemophilia B (HB) showed that the risk of cellular immune response to vector capsid is clearly dos

251 duce stronger effector memory T cell-biased, cellular immune responses to a coexpressed Ag despite pr

252 was required for early innate and subsequent cellular immune responses to a model IMX vaccine.

253 le of eliciting long-lasting effector-memory cellular immune responses to all nine SIV gene products.

254 Cellular immune responses to all particle-based vaccine

255 The presence of humoral and cellular immune responses to ASP in HIV-1 patients indic

256 and, CD70, has been implicated in regulating cellular immune responses to cancer.

257 o generated robust neutralizing antibody and cellular immune responses to CHIKV in mice after a singl

258 significantly enhances adaptive antibody and cellular immune responses to codelivered antigens.

259 The humoral and cellular immune responses to DBs were compared to the im

260 red IgG binding, neutralizing antibodies and cellular immune responses to Ebolavirus (EBOV) glycoprot

261 Cellular immune responses to gD-2 did not correlate with

262 ting virus, evidence for HIV superinfection, cellular immune responses to HIV, as well as an examinat

263 he rAd5-EAT-2 vaccine can also induce potent cellular immune responses to HIV-1 Ags despite the prese

264 though we now have a detailed picture of the cellular immune responses to HIV-1, important questions

265 Secondary outcomes were humoral and cellular immune responses to immunization, as assessed b

266 Robust cellular immune responses to influenza during pregnancy

267 With the serological and cellular immune responses to influenza vaccination being

268 Assessment of cellular immune responses to known CD8(+) T cell antigen

269 ization of several aspects of the innate and cellular immune responses to Lassa virus.

270 in humans rely on peripheral blood to assess cellular immune responses to malaria.

271 ial cells, and (vi) GT-DB and TFF-DB induced cellular immune responses to multiple HCMV peptides.

272 both ferrets and mice generated humoral and cellular immune responses to MuV-IA infection, no obviou

273 xposed to sand fly bites develop humoral and cellular immune responses to sand fly salivary proteins.

274 immunohistochemical analyses, we delineated cellular immune responses to SARS-CoV-2 infection in mac

275 t is currently known about human humoral and cellular immune responses to severe acute respiratory sy

276 7 in the generation of robust, high-affinity cellular immune responses to subunit immunization.

277 es containing such adaptations may undermine cellular immune responses to the incoming virus in futur

278 All 3 regimens induced systemic cellular immune responses to the modified vaccinia virus

279 lutinin 222G viral mutation, and humoral and cellular immune responses to the virus, assessed in hema

280 ion of 3M-052 enhanced antibody and TH1-type cellular immune responses to vaccine antigens for tuberc

281 atory responses and control the magnitude of cellular immune responses to viral infections.

282 The cellular immune response toward scaffolds was evaluated

283 olymorphisms and adaptations associated with cellular immune responses, underscoring the complex mole

284 roups, a positive correlation of humoral and cellular immune response was seen as high/low TBE titers

285 Past the peak of the cellular immune response, we report a gradient of FOXO1

286 100 genes involved in the cellular immune response were sequenced and a missense m

287 adverse events (AEs) as well as humoral and cellular immune responses were assessed after each injec

288 Similarly, although potent cellular immune responses were detected against determin

289 G3, tier 1A neutralising activity, and broad cellular immune responses were detected in all groups.

290 n strategies eliciting unmatched humoral and cellular immune responses were identified.

291 Cellular immune responses were measured by intracellular

292 roparticles could trigger humoral as well as cellular immune response when administered transdermally

293 k the ability to significantly stimulate the cellular immune response, which is required to prevent t

294 IDS vaccine should elicit strong humoral and cellular immune responses while maintaining low levels o

295 typically elicit a neutralizing antibody and cellular immune response, while establishing a dormant i

296 Humoral immunity is complemented by a cellular immune response with favourable T helper 1 pola

297 IV Vaccine Trials Network 083 tested whether cellular immune responses with these features are induce

298 oincided with an intense innate and adaptive cellular immune response, with infiltrating leukocytes a

299 uced SIV-specific IgA and IgG antibodies and cellular immune responses within weeks of life.

300 generated increases in specific humoral and cellular immune responses without raising significant sa